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Contributions of each of the BAFF receptors to the lymphocyte profiles in C57BL/6 mice. Immunology. 2024 Aug 31.
Stohl W, Wu Y, Stohl M. PMID: 39215598.
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PubMed Mentions:
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T cell Dissimilarities in B Cell Activating Factor-Deficient Versus B Cell Activating Factor Receptor 3-Deficient Systemic Lupus Erythematosus-Prone NZM 2328 Mice as Contributors to Their Divergent Clinical Outcomes. ACR Open Rheumatol. 2024 Aug 14.
Stohl W, Wu Y, Stohl M. PMID: 39143363.
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PubMed Mentions:
-
Innate and adaptive immune cell interaction drives inflammasome activation and hepatocyte apoptosis in murine liver injury from immune checkpoint inhibitors. Cell Death Dis. 2024 Feb 14; 15(2):140.
Shojaie L, Bogdanov JM, Alavifard H, Mohamed MG, Baktash A, Ali M, Mahov S, Murray S, Kanel GC, Liu ZX, Ito F, In GK, Merchant A, Stohl W, Dara L. PMID: 38355725; PMCID: PMC10866933.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
-
Industry Payments to United States Rheumatologist-Authors of Publications in High-Impact Rheumatology Journals. ACR Open Rheumatol. 2023 Nov; 5(11):609-618.
Stohl W, Parikh K. PMID: 37675758; PMCID: PMC10642244.
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PubMed Mentions:
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Impaired dynamic X-chromosome inactivation maintenance in T cells is a feature of spontaneous murine SLE that is exacerbated in female-biased models. J Autoimmun. 2023 09; 139:103084.
Jiwrajka N, Toothacre NE, Beethem ZT, Sting S, Forsyth KS, Dubin AH, Driscoll A, Stohl W, Anguera MC. PMID: 37399593; PMCID: PMC11140471.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
-
Isoform-specific knockdown of long and intermediate prolactin receptors interferes with evolution of B-cell neoplasms. Commun Biol. 2023 03 20; 6(1):295.
Taghi Khani A, Kumar A, Sanchez Ortiz A, Radecki KC, Aramburo S, Lee SJ, Hu Z, Damirchi B, Lorenson MY, Wu X, Gu Z, Stohl W, Sanz I, Meffre E, Müschen M, Forman SJ, Koff JL, Walker AM, Swaminathan S. PMID: 36941341; PMCID: PMC10027679.
View in:
PubMed Mentions:
1 Translation:
HumansAnimals
-
Belimumab for the treatment of pediatric patients with lupus nephritis. Expert Opin Biol Ther. 2023 03; 23(3):243-251.
Stohl W, Kwok A. PMID: 36750049.
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PubMed Mentions:
5 Fields:
Translation:
Humans
-
Maternal and cord blood BAFF and APRIL levels during pregnancy. Am J Reprod Immunol. 2023 03; 89(3):e13654.
Stohl HE, Stohl W. PMID: 36398594.
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PubMed Mentions:
2 Fields:
Translation:
Humans
-
B Cell and T Cell Dissimilarities in BAFF-Deficient versus BR3-Deficient C57BL/6 Mice. J Immunol. 2022 12 01; 209(11):2133-2140.
Stohl W, Yu N, Wu Y. PMID: 36426969.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
-
Impact of Belimumab on Organ Damage in Systemic Lupus Erythematosus. Arthritis Care Res (Hoboken). 2022 11; 74(11):1822-1828.
Urowitz MB, Aranow C, Asukai Y, Bass DL, Bruce IN, Chauhan D, Dall'Era M, Furie R, Fox NL, Gilbride JA, Hammer A, Ginzler EM, Gonzalez-Rivera T, Levy RA, Merrill JT, Quasny H, Roth DA, Stohl W, van Vollenhoven R, Wallace DJ, Petri M. PMID: 35439360; PMCID: PMC9805003.
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PubMed Mentions:
6 Fields:
Translation:
Humans
-
Preferential Expansion of Foxp3+ T Regulatory Cells in CTLA-4-Deficient and CTLA-4-Haploinsufficient C57BL/6 Mice. Immunohorizons. 2022 07 25; 6(7):507-514.
Stohl W, Yu N, Wu Y. PMID: 35878937.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
-
Reductions in circulating B cell subsets and immunoglobulin G levels with long-term belimumab treatment in patients with SLE. Lupus Sci Med. 2022 02; 9(1).
Struemper H, Kurtinecz M, Edwards L, Freimuth WW, Roth DA, Stohl W. PMID: 35131846; PMCID: PMC8823257.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
-
First-trimester serum BAFF:sFlt-1 ratio as a candidate early biomarker of spontaneous abortion. Am J Reprod Immunol. 2021 10; 86(4):e13428.
Stohl HE, Yu N, Stohl W. PMID: 33837577.
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PubMed Mentions:
2 Fields:
Translation:
Humans
-
Novel signatures associated with systemic lupus erythematosus clinical response to IFN-α/-ω inhibition. Lupus. 2021 Apr; 30(5):795-806.
Seridi L, Cesaroni M, Orillion A, Schreiter J, Chevrier M, Marciniak S, Migone TS, Stohl W, Chatham WW, Furie RA, Benson J, Jordan J. PMID: 33626969.
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PubMed Mentions: Fields:
Translation:
HumansCellsCTClinical Trials
-
Filgotinib in combination with methotrexate or as monotherapy versus methotrexate monotherapy in patients with active rheumatoid arthritis and limited or no prior exposure to methotrexate: the phase 3, randomised controlled FINCH 3 trial. Ann Rheum Dis. 2021 06; 80(6):727-738.
Westhovens R, Rigby WFC, van der Heijde D, Ching DWT, Stohl W, Kay J, Chopra A, Bartok B, Matzkies F, Yin Z, Guo Y, Tasset C, Sundy JS, Jahreis A, Mozaffarian N, Messina OD, Landewé RB, Atsumi T, Burmester GR. PMID: 33452004; PMCID: PMC8142453.
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PubMed Mentions:
43 Fields:
Translation:
HumansAnimalsCTClinical Trials
-
Inhibition of B cell activation following in vivo co-engagement of B cell antigen receptor and Fcγ receptor IIb in non-autoimmune-prone and SLE-prone mice. J Transl Autoimmun. 2021; 4:100075.
Chu SY, Pong E, Bonzon C, Yu N, Jacob CO, Chalmers SA, Putterman C, Szymkowski DE, Stohl W. PMID: 33409482; PMCID: PMC7773957.
View in:
PubMed Mentions:
4
-
Mortality and adverse events of special interest with intravenous belimumab for adults with active, autoantibody-positive systemic lupus erythematosus (BASE): a multicentre, double-blind, randomised, placebo-controlled, phase 4 trial. Lancet Rheumatol. 2021 Feb; 3(2):e122-e130.
Sheikh SZ, Scheinberg MA, Wei JC, Tegzova D, Stohl W, de Toledo RA, Mucenic T, Banfi MRA, Maksimowicz-McKinnon K, Abud-Mendoza C, Navarra S, Garcia M, Garcia-De La Torre I, Ros JO, Levy RA, Bass DL, Terrés JR, Punwaney R, Harris J, Nami A, Pierce A, Thorneloe KS, Ji B, Roth DA. PMID: 38279368.
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PubMed Mentions:
4 Fields:
-
Systemic lupus erythematosus (SLE): emerging therapeutic targets. Expert Opin Ther Targets. 2020 12; 24(12):1283-1302.
Mathias LM, Stohl W. PMID: 33034541.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimals
-
First-in-Human study of JNJ-55920839 in healthy volunteers and patients with systemic lupus erythematosus: a randomised placebo-controlled phase 1 trial. Lancet Rheumatol. 2020 Oct; 2(10):e613-e622.
Jordan J, Benson J, Chatham WW, Furie RA, Stohl W, Wei JC, Marciniak S, Yao Z, Srivastava B, Schreiter J, Cesaroni M, Orillion A, Seridi L, Chevrier M. PMID: 38273624.
View in:
PubMed Mentions:
3 Fields:
-
Belimumab and Rituximab in Systemic Lupus Erythematosus: A Tale of Two B Cell-Targeting Agents. Front Med (Lausanne). 2020; 7:303.
Wise LM, Stohl W. PMID: 32695790; PMCID: PMC7338653.
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PubMed Mentions:
32
-
Circulating TNF-like protein 1A (TL1A) is elevated early in rheumatoid arthritis and depends on TNF. Arthritis Res Ther. 2020 05 07; 22(1):106.
Song YJ, Choi IA, Meylan F, Demoruelle MK, Farley T, Richard AC, Hawley E, Botson J, Hong YJ, Lee EY, Mian SR, Hamilton BC, Thiele GM, Mikuls TR, Gara N, Ward CD, Lamberth S, Deane KD, Heller T, Ward MM, Lee DM, Migone TS, Stohl W, O'Dell JR, Norris JM, Holers VM, Gregersen P, Song YW, Siegel RM. PMID: 32381123; PMCID: PMC7204024.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
-
Promotion of T Regulatory Cells in Mice by B Cells and BAFF. J Immunol. 2020 05 01; 204(9):2416-2428.
Stohl W, Yu N. PMID: 32213563.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
-
Development of Murine Systemic Lupus Erythematosus in the Absence of BAFF. Arthritis Rheumatol. 2020 02; 72(2):292-302.
Stohl W, Yu N, Chalmers S, Putterman C, Jacob CO. PMID: 31493335; PMCID: PMC6994329.
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PubMed Mentions:
3 Fields:
Translation:
Animals
-
The safety of belimumab for the treatment of systemic lupus erythematosus. Expert Opin Drug Saf. 2019 Dec; 18(12):1133-1144.
Wise LM, Stohl W. PMID: 31657965.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimals
-
Safety and Efficacy of Belimumab Plus Standard Therapy for Up to Thirteen Years in Patients With Systemic Lupus Erythematosus. Arthritis Rheumatol. 2019 07; 71(7):1125-1134.
Wallace DJ, Ginzler EM, Merrill JT, Furie RA, Stohl W, Chatham WW, Weinstein A, McKay JD, McCune WJ, Petri M, Fettiplace J, Roth DA, Ji B, Heath A. PMID: 30771238; PMCID: PMC6617785.
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PubMed Mentions:
38 Fields:
Translation:
Humans
-
IgM Plasma Cells Reside in Healthy Skin and Accumulate with Chronic Inflammation. J Invest Dermatol. 2019 12; 139(12):2477-2487.
Wilson RP, McGettigan SE, Dang VD, Kumar A, Cancro MP, Nikbakht N, Stohl W, Debes GF. PMID: 31152755; PMCID: PMC6874734.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
-
Elevated serum globulin gap as a highly reliable marker of elevated erythrocyte sedimentation rate in patients with systemic rheumatic diseases. Semin Arthritis Rheum. 2019 12; 49(3):485-492.
Stohl W, Kenol B, Kelly AJ, Ananth Correa A, Panush RS. PMID: 31153707.
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PubMed Mentions:
10 Fields:
Translation:
Humans
-
Constitutive reduction in the checkpoint inhibitor, CTLA-4, does not accelerate SLE in NZM 2328 mice. Lupus Sci Med. 2019; 6(1):e000313.
Stohl W, Yu N, Chalmers SA, Putterman C, Jacob CO. PMID: 31168399; PMCID: PMC6519407.
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PubMed Mentions:
2 Fields:
-
Clinical response beyond the Systemic Lupus Erythematosus Responder Index: post-hoc analysis of the BLISS-SC study. Lupus Sci Med. 2018; 5(1):e000288.
van Vollenhoven RF, Stohl W, Furie RA, Fox NL, Groark JG, Bass D, Kurtinecz M, Pobiner BF, Eastman WJ, Gonzalez-Rivera T, Gordon D. PMID: 30588323; PMCID: PMC6280901.
View in:
PubMed Mentions:
3 Fields:
-
Increased Cathepsin S activity associated with decreased protease inhibitory capacity contributes to altered tear proteins in Sjögren's Syndrome patients. Sci Rep. 2018 07 23; 8(1):11044.
Edman MC, Janga SR, Meng Z, Bechtold M, Chen AF, Kim C, Naman L, Sarma A, Teekappanavar N, Kim AY, Madrigal S, Singh S, Ortiz E, Christianakis S, Arkfeld DG, Mack WJ, Heur M, Stohl W, Hamm-Alvarez SF. PMID: 30038391; PMCID: PMC6056496.
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PubMed Mentions:
28 Fields:
Translation:
HumansAnimals
-
Efficacy and Safety of Subcutaneous Belimumab in Anti-Double-Stranded DNA-Positive, Hypocomplementemic Patients With Systemic Lupus Erythematosus. Arthritis Rheumatol. 2018 08; 70(8):1256-1264.
Doria A, Stohl W, Schwarting A, Okada M, Scheinberg M, van Vollenhoven R, Hammer AE, Groark J, Bass D, Fox NL, Roth D, Gordon D. PMID: 29671280; PMCID: PMC6099508.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansCTClinical Trials
-
A 6-month open-label extension study of the safety and efficacy of subcutaneous belimumab in patients with systemic lupus erythematosus. Lupus. 2018 Aug; 27(9):1489-1498.
Doria A, Bass D, Schwarting A, Hammer A, Gordon D, Scheinberg M, Fox NL, Groark J, Stohl W, Kleoudis C, Roth D. PMID: 29807477; PMCID: PMC6066857.
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PubMed Mentions:
13 Fields:
Translation:
HumansCTClinical Trials
-
Maternal Serum B-Cell Activating Factor Levels: Candidate Early Biomarker for Hypertensive Disorders of Pregnancy. Hypertension. 2017 11; 70(5):1007-1013.
Stohl HE, Lee RH, Manetta J, Kikly K, Korst LM, Stohl W. PMID: 28923901.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
-
Systemic lupus erythematosus: BAFF emerges from the genetic shadows. Nat Rev Rheumatol. 2017 08; 13(8):456-457.
Stohl W. PMID: 28615729.
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PubMed Mentions:
1 Fields:
Translation:
Humans
-
Efficacy and Safety of Subcutaneous Belimumab in Systemic Lupus Erythematosus: A Fifty-Two-Week Randomized, Double-Blind, Placebo-Controlled Study. Arthritis Rheumatol. 2017 05; 69(5):1016-1027.
Stohl W, Schwarting A, Okada M, Scheinberg M, Doria A, Hammer AE, Kleoudis C, Groark J, Bass D, Fox NL, Roth D, Gordon D. PMID: 28118533; PMCID: PMC5434872.
View in:
PubMed Mentions:
144 Fields:
Translation:
Humans
-
A TLR9-dependent checkpoint governs B cell responses to DNA-containing antigens. J Clin Invest. 2017 May 01; 127(5):1651-1663.
Sindhava VJ, Oropallo MA, Moody K, Naradikian M, Higdon LE, Zhou L, Myles A, Green N, Nündel K, Stohl W, Schmidt AM, Cao W, Dorta-Estremera S, Kambayashi T, Marshak-Rothstein A, Cancro MP. PMID: 28346226; PMCID: PMC5409796.
View in:
PubMed Mentions:
48 Fields:
Translation:
AnimalsCells
-
Inhibition of B cell activating factor (BAFF) in the management of systemic lupus erythematosus (SLE). Expert Rev Clin Immunol. 2017 06; 13(6):623-633.
Stohl W. PMID: 28164726.
View in:
PubMed Mentions:
23 Fields:
Translation:
Humans
-
Serum progranulin levels in Hispanic rheumatoid arthritis patients treated with TNF antagonists: a prospective, observational study. Clin Rheumatol. 2017 Mar; 36(3):507-516.
Johnson J, Yeter K, Rajbhandary R, Neal R, Tian Q, Jian J, Fadle N, Thurner L, Liu C, Stohl W. PMID: 27830341.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
B cell-independent contribution of BAFF to murine autoimmune disease. Clin Immunol. 2016 Nov; 172:111-116.
Stohl W, Banfalvi A. PMID: 27430521.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
-
Differential Development of Systemic Lupus Erythematosus in NZM 2328 Mice Deficient in Discrete Pairs of BAFF Receptors. Arthritis Rheumatol. 2015 Sep; 67(9):2523-35.
Jacob CO, Yu N, Sindhava V, Cancro MP, Pawar RD, Putterman C, Stohl W. PMID: 25989238.
View in:
PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
-
Treatment of systemic lupus erythematosus patients with the BAFF antagonist "peptibody" blisibimod (AMG 623/A-623): results from randomized, double-blind phase 1a and phase 1b trials. Arthritis Res Ther. 2015 Aug 20; 17:215.
Stohl W, Merrill JT, Looney RJ, Buyon J, Wallace DJ, Weisman MH, Ginzler EM, Cooke B, Holloway D, Kaliyaperumal A, Kuchimanchi KR, Cheah TC, Rasmussen E, Ferbas J, Belouski SS, Tsuji W, Zack DJ. PMID: 26290435; PMCID: PMC4545922.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansCellsCTClinical Trials
-
Efficacy and safety of subcutaneous tabalumab, a monoclonal antibody to B-cell activating factor, in patients with systemic lupus erythematosus: results from ILLUMINATE-2, a 52-week, phase III, multicentre, randomised, double-blind, placebo-controlled study. Ann Rheum Dis. 2016 Feb; 75(2):332-40.
Merrill JT, van Vollenhoven RF, Buyon JP, Furie RA, Stohl W, Morgan-Cox M, Dickson C, Anderson PW, Lee C, Berclaz PY, Dörner T. PMID: 26293163.
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PubMed Mentions:
79 Fields:
Translation:
HumansCellsCTClinical Trials
-
A dendritic-cell-stromal axis maintains immune responses in lymph nodes. Immunity. 2015 Apr 21; 42(4):719-30.
Kumar V, Dasoveanu DC, Chyou S, Tzeng TC, Rozo C, Liang Y, Stohl W, Fu YX, Ruddle NH, Lu TT. PMID: 25902483; PMCID: PMC4591553.
View in:
PubMed Mentions:
46 Fields:
Translation:
AnimalsCells
-
Editorial: the BAFFling immunology of systemic lupus erythematosus: beyond B cells. Arthritis Rheumatol. 2015 Mar; 67(3):612-5.
Stohl W. PMID: 25385361.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
-
Tear cathepsin S as a candidate biomarker for Sjögren's syndrome. Arthritis Rheumatol. 2014 Jul; 66(7):1872-81.
Hamm-Alvarez SF, Janga SR, Edman MC, Madrigal S, Shah M, Frousiakis SE, Renduchintala K, Zhu J, Bricel S, Silka K, Bach D, Heur M, Christianakis S, Arkfeld DG, Irvine J, Mack WJ, Stohl W. PMID: 24644101; PMCID: PMC4077975.
View in:
PubMed Mentions:
60 Fields:
Translation:
HumansAnimals
-
Suppression of rheumatoid arthritis B cells by XmAb5871, an anti-CD19 antibody that coengages B cell antigen receptor complex and Fcγ receptor IIb inhibitory receptor. Arthritis Rheumatol. 2014 May; 66(5):1153-64.
Chu SY, Yeter K, Kotha R, Pong E, Miranda Y, Phung S, Chen H, Lee SH, Leung I, Bonzon C, Desjarlais JR, Stohl W, Szymkowski DE. PMID: 24782179.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansAnimalsCells
-
Therapeutic targeting of the BAFF/APRIL axis in systemic lupus erythematosus. Expert Opin Ther Targets. 2014 Apr; 18(4):473-89.
Stohl W. PMID: 24521424.
View in:
PubMed Mentions:
29 Fields:
Translation:
HumansAnimals
-
APRIL mediates peritoneal B-1 cell homeostasis. Immunol Lett. 2014 Aug; 160(2):120-7.
Sindhava VJ, Scholz JL, Stohl W, Cancro MP. PMID: 24512739; PMCID: PMC4058418.
View in:
PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
-
Lloyd Mayer, MD, 1952-2013, In Memoriam. Clin Immunol. 2014 Feb; 150(2):A1-A2.
Fu SM, Cunningham-Rundles C, Diamond B, Rotrosen D, Stohl W, Terhorst C. PMID: 32942520.
View in:
PubMed Mentions: Fields:
-
Local BLyS production by T follicular cells mediates retention of high affinity B cells during affinity maturation. J Exp Med. 2014 Jan 13; 211(1):45-56.
Goenka R, Matthews AH, Zhang B, O'Neill PJ, Scholz JL, Migone TS, Leonard WJ, Stohl W, Hershberg U, Cancro MP. PMID: 24367004; PMCID: PMC3892970.
View in:
PubMed Mentions:
63 Fields:
Translation:
AnimalsCells
-
Disease control and safety of belimumab plus standard therapy over 7 years in patients with systemic lupus erythematosus. J Rheumatol. 2014 Feb; 41(2):300-9.
Ginzler EM, Wallace DJ, Merrill JT, Furie RA, Stohl W, Chatham WW, Weinstein A, McKay JD, McCune WJ, Zhong ZJ, Freimuth WW, Petri MA, LBSL02/99 Study Group. PMID: 24187095.
View in:
PubMed Mentions:
52 Fields:
Translation:
HumansCTClinical Trials
-
Future prospects in biologic therapy for systemic lupus erythematosus. Nat Rev Rheumatol. 2013 Dec; 9(12):705-20.
Stohl W. PMID: 24018550.
View in:
PubMed Mentions:
27 Fields:
Translation:
Humans
-
BAFF- and APRIL-dependent maintenance of antibody titers after immunization with T-dependent antigen and CD1d-binding ligand. J Immunol. 2013 Aug 01; 191(3):1154-63.
Shah HB, Joshi SK, Rampuria P, Devera TS, Lang GA, Stohl W, Lang ML. PMID: 23797666; PMCID: PMC3720783.
View in:
PubMed Mentions:
18 Fields:
Translation:
AnimalsCellsPHPublic Health
-
Development of systemic lupus erythematosus in NZM 2328 mice in the absence of any single BAFF receptor. Arthritis Rheum. 2013 Apr; 65(4):1043-54.
Jacob CO, Yu N, Guo S, Jacob N, Quinn WJ, Sindhava V, Cancro MP, Goilav B, Putterman C, Migone TS, Stohl W. PMID: 23334904; PMCID: PMC3618582.
View in:
PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
-
Efficacy and safety of belimumab in patients with rheumatoid arthritis: a phase II, randomized, double-blind, placebo-controlled, dose-ranging Study. J Rheumatol. 2013 May; 40(5):579-89.
Stohl W, Merrill JT, McKay JD, Lisse JR, Zhong ZJ, Freimuth WW, Genovese MC. PMID: 23547209.
View in:
PubMed Mentions:
42 Fields:
Translation:
HumansCTClinical Trials
-
Racial/ethnic differences in the use of biologic disease-modifying antirheumatic drugs among California Medicaid rheumatoid arthritis patients. Arthritis Care Res (Hoboken). 2013 Feb; 65(2):299-303.
Chu LH, Portugal C, Kawatkar AA, Stohl W, Nichol MB. PMID: 22807272.
View in:
PubMed Mentions:
20 Fields:
Translation:
Humans
-
Biologic differences between various inhibitors of the BLyS/BAFF pathway: should we expect differences between belimumab and other inhibitors in development? Curr Rheumatol Rep. 2012 Aug; 14(4):303-9.
Stohl W. PMID: 22547203.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansAnimals
-
Induced T regulatory cells suppress osteoclastogenesis and bone erosion in collagen-induced arthritis better than natural T regulatory cells. Ann Rheum Dis. 2012 Sep; 71(9):1567-1572.
Kong N, Lan Q, Su W, Chen M, Wang J, Yang Z, Park R, Dagliyan G, Conti PS, Brand D, Liu Z, Stohl W, Zou H, Zheng SG. PMID: 22764040; PMCID: PMC4038329.
View in:
PubMed Mentions:
56 Fields:
Translation:
AnimalsCells
-
Belimumab reduces autoantibodies, normalizes low complement levels, and reduces select B cell populations in patients with systemic lupus erythematosus. Arthritis Rheum. 2012 Jul; 64(7):2328-37.
Stohl W, Hiepe F, Latinis KM, Thomas M, Scheinberg MA, Clarke A, Aranow C, Wellborne FR, Abud-Mendoza C, Hough DR, Pineda L, Migone TS, Zhong ZJ, Freimuth WW, Chatham WW, BLISS-52 Study Group, BLISS-76 Study Group. PMID: 22275291; PMCID: PMC3350827.
View in:
PubMed Mentions:
152 Fields:
Translation:
HumansCells
-
Incremental expenditure of biologic disease modifying antirheumatic treatment using instrumental variables in panel data. Health Econ. 2013 Jul; 22(7):807-23.
Kawatkar AA, Hay JW, Stohl W, Nichol MB. PMID: 22718267.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Effect of belimumab on vaccine antigen antibodies to influenza, pneumococcal, and tetanus vaccines in patients with systemic lupus erythematosus in the BLISS-76 trial. J Rheumatol. 2012 Aug; 39(8):1632-40.
Chatham WW, Wallace DJ, Stohl W, Latinis KM, Manzi S, McCune WJ, Tegzová D, McKay JD, Avila-Armengol HE, Utset TO, Zhong ZJ, Hough DR, Freimuth WW, Migone TS, BLISS-76 Study Group. PMID: 22707609.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansCTClinical Trials
-
Dispensability of APRIL to the development of systemic lupus erythematosus in NZM 2328 mice. Arthritis Rheum. 2012 May; 64(5):1610-9.
Jacob CO, Guo S, Jacob N, Pawar RD, Putterman C, Quinn WJ, Cancro MP, Migone TS, Stohl W. PMID: 22127792; PMCID: PMC3292707.
View in:
PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
-
Safety and efficacy of ocrelizumab in combination with methotrexate in MTX-naive subjects with rheumatoid arthritis: the phase III FILM trial. Ann Rheum Dis. 2012 Aug; 71(8):1289-96.
Stohl W, Gomez-Reino J, Olech E, Dudler J, Fleischmann RM, Zerbini CA, Ashrafzadeh A, Grzeschik S, Bieraugel R, Green J, Francom S, Dummer W. PMID: 22307942; PMCID: PMC3396459.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansCTClinical Trials
-
The discovery and development of belimumab: the anti-BLyS-lupus connection. Nat Biotechnol. 2012 Jan 09; 30(1):69-77.
Stohl W, Hilbert DM. PMID: 22231104; PMCID: PMC3264947.
View in:
PubMed Mentions:
61 Fields:
Translation:
HumansAnimalsCells
-
A phase III, randomized, placebo-controlled study of belimumab, a monoclonal antibody that inhibits B lymphocyte stimulator, in patients with systemic lupus erythematosus. Arthritis Rheum. 2011 Dec; 63(12):3918-30.
Furie R, Petri M, Zamani O, Cervera R, Wallace DJ, Tegzová D, Sanchez-Guerrero J, Schwarting A, Merrill JT, Chatham WW, Stohl W, Ginzler EM, Hough DR, Zhong ZJ, Freimuth W, van Vollenhoven RF, BLISS-76 Study Group. PMID: 22127708; PMCID: PMC5007058.
View in:
PubMed Mentions:
543 Fields:
Translation:
HumansCTClinical Trials
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Sustained inhibition of progressive joint damage with rituximab plus methotrexate in early active rheumatoid arthritis: 2-year results from the randomised controlled trial IMAGE. Ann Rheum Dis. 2012 Mar; 71(3):351-7.
Tak PP, Rigby W, Rubbert-Roth A, Peterfy C, van Vollenhoven RF, Stohl W, Healy E, Hessey E, Reynard M, Shaw T. PMID: 22012969; PMCID: PMC3277723.
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PubMed Mentions:
43 Fields:
Translation:
Humans
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BAFF promotes Th17 cells and aggravates experimental autoimmune encephalomyelitis. PLoS One. 2011; 6(8):e23629.
Zhou X, Xia Z, Lan Q, Wang J, Su W, Han YP, Fan H, Liu Z, Stohl W, Zheng SG. PMID: 21897850; PMCID: PMC3163640.
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PubMed Mentions:
33 Fields:
Translation:
HumansAnimalsCells
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Cytokine disturbances in systemic lupus erythematosus. Arthritis Res Ther. 2011 Jul 06; 13(4):228.
Jacob N, Stohl W. PMID: 21745419; PMCID: PMC3239336.
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PubMed Mentions:
63 Fields:
Translation:
HumansAnimals
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Targeting BLyS in rheumatic disease: the sometimes-bumpy road from bench to bedside. Curr Opin Rheumatol. 2011 May; 23(3):305-10.
Stohl W, Scholz JL, Cancro MP. PMID: 21330926; PMCID: PMC3154025.
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PubMed Mentions:
26 Translation:
HumansAnimalsCells
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B Cell and BAFF dependence of IFN-α-exaggerated disease in systemic lupus erythematosus-prone NZM 2328 mice. J Immunol. 2011 Apr 15; 186(8):4984-93.
Jacob N, Guo S, Mathian A, Koss MN, Gindea S, Putterman C, Jacob CO, Stohl W. PMID: 21383240; PMCID: PMC3074466.
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PubMed Mentions:
40 Fields:
Translation:
AnimalsCells
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Antibody-mediated coengagement of FcγRIIb and B cell receptor complex suppresses humoral immunity in systemic lupus erythematosus. J Immunol. 2011 Apr 01; 186(7):4223-33.
Horton HM, Chu SY, Ortiz EC, Pong E, Cemerski S, Leung IW, Jacob N, Zalevsky J, Desjarlais JR, Stohl W, Szymkowski DE. PMID: 21357255.
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PubMed Mentions:
57 Fields:
Translation:
HumansAnimalsCells
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Inhibition of joint damage and improved clinical outcomes with rituximab plus methotrexate in early active rheumatoid arthritis: the IMAGE trial. Ann Rheum Dis. 2011 Jan; 70(1):39-46.
Tak PP, Rigby WF, Rubbert-Roth A, Peterfy CG, van Vollenhoven RF, Stohl W, Hessey E, Chen A, Tyrrell H, Shaw TM, IMAGE Investigators. PMID: 20937671.
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PubMed Mentions:
97 Fields:
Translation:
HumansCTClinical Trials
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Constitutive overexpression of BAFF in autoimmune-resistant mice drives only some aspects of systemic lupus erythematosus-like autoimmunity. Arthritis Rheum. 2010 Aug; 62(8):2432-42.
Stohl W, Jacob N, Guo S, Morel L. PMID: 20506216; PMCID: PMC2921019.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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Systemic lupus erythematosus and its ABCs (APRIL/BLyS complexes). Arthritis Res Ther. 2010; 12(2):111.
Stohl W. PMID: 20441604; PMCID: PMC2888214.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Association of the response to tumor necrosis factor antagonists with plasma type I interferon activity and interferon-beta/alpha ratios in rheumatoid arthritis patients: a post hoc analysis of a predominantly Hispanic cohort. Arthritis Rheum. 2010 Feb; 62(2):392-401.
Mavragani CP, La DT, Stohl W, Crow MK. PMID: 20112385; PMCID: PMC2821991.
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PubMed Mentions:
33 Fields:
Translation:
HumansCTClinical Trials
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Autoantibody-dependent and autoantibody-independent roles for B cells in systemic lupus erythematosus: past, present, and future. Autoimmunity. 2010 Feb; 43(1):84-97.
Jacob N, Stohl W. PMID: 20014977; PMCID: PMC2809122.
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PubMed Mentions:
30 Fields:
Translation:
HumansAnimalsCells
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B lymphocyte stimulator expression in pediatric systemic lupus erythematosus and juvenile idiopathic arthritis patients. Arthritis Rheum. 2009 Nov; 60(11):3400-9.
Hong SD, Reiff A, Yang HT, Migone TS, Ward CD, Marzan K, Shaham B, Phei WC, Garza J, Bernstein B, Stohl W. PMID: 19877053.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Deficiency of type I IFN receptor in lupus-prone New Zealand mixed 2328 mice decreases dendritic cell numbers and activation and protects from disease. J Immunol. 2009 Nov 01; 183(9):6021-9.
Agrawal H, Jacob N, Carreras E, Bajana S, Putterman C, Turner S, Neas B, Mathian A, Koss MN, Stohl W, Kovats S, Jacob CO. PMID: 19812195; PMCID: PMC2766036.
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PubMed Mentions:
81 Fields:
Translation:
HumansAnimalsCells
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Urinary TWEAK as a biomarker of lupus nephritis: a multicenter cohort study. Arthritis Res Ther. 2009; 11(5):R143.
Schwartz N, Rubinstein T, Burkly LC, Collins CE, Blanco I, Su L, Hojaili B, Mackay M, Aranow C, Stohl W, Rovin BH, Michaelson JS, Putterman C. PMID: 19785730; PMCID: PMC2787265.
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PubMed Mentions:
86 Fields:
Translation:
Humans
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A phase II, randomized, double-blind, placebo-controlled, dose-ranging study of belimumab in patients with active systemic lupus erythematosus. Arthritis Rheum. 2009 Sep 15; 61(9):1168-78.
Wallace DJ, Stohl W, Furie RA, Lisse JR, McKay JD, Merrill JT, Petri MA, Ginzler EM, Chatham WW, McCune WJ, Fernandez V, Chevrier MR, Zhong ZJ, Freimuth WW. PMID: 19714604; PMCID: PMC2758229.
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PubMed Mentions:
193 Fields:
Translation:
HumansCTClinical Trials
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Novel evidence-based systemic lupus erythematosus responder index. Arthritis Rheum. 2009 Sep 15; 61(9):1143-51.
Furie RA, Petri MA, Wallace DJ, Ginzler EM, Merrill JT, Stohl W, Chatham WW, Strand V, Weinstein A, Chevrier MR, Zhong ZJ, Freimuth WW. PMID: 19714615; PMCID: PMC2748175.
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PubMed Mentions:
145 Fields:
Translation:
Humans
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Accelerated pathological and clinical nephritis in systemic lupus erythematosus-prone New Zealand Mixed 2328 mice doubly deficient in TNF receptor 1 and TNF receptor 2 via a Th17-associated pathway. J Immunol. 2009 Feb 15; 182(4):2532-41.
Jacob N, Yang H, Pricop L, Liu Y, Gao X, Zheng SG, Wang J, Gao HX, Putterman C, Koss MN, Stohl W, Jacob CO. PMID: 19201910; PMCID: PMC2790862.
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PubMed Mentions:
54 Fields:
Translation:
AnimalsCells
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Elevated synovial expression of triggering receptor expressed on myeloid cells 1 in patients with septic arthritis or rheumatoid arthritis. Ann Rheum Dis. 2009 Nov; 68(11):1768-74.
Collins CE, La DT, Yang HT, Massin F, Gibot S, Faure G, Stohl W. PMID: 19054829.
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PubMed Mentions:
44 Fields:
Translation:
HumansCells
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Biologic activity and safety of belimumab, a neutralizing anti-B-lymphocyte stimulator (BLyS) monoclonal antibody: a phase I trial in patients with systemic lupus erythematosus. Arthritis Res Ther. 2008; 10(5):R109.
Furie R, Stohl W, Ginzler EM, Becker M, Mishra N, Chatham W, Merrill JT, Weinstein A, McCune WJ, Zhong J, Cai W, Freimuth W, Belimumab Study Group. PMID: 18786258; PMCID: PMC2592791.
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PubMed Mentions:
83 Fields:
Translation:
HumansCellsCTClinical Trials
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Association of plasma B lymphocyte stimulator levels and disease activity in systemic lupus erythematosus. Arthritis Rheum. 2008 Aug; 58(8):2453-9.
Petri M, Stohl W, Chatham W, McCune WJ, Chevrier M, Ryel J, Recta V, Zhong J, Freimuth W. PMID: 18668552.
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PubMed Mentions:
143 Fields:
Translation:
Humans
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Global T cell dysregulation in non-autoimmune-prone mice promotes rapid development of BAFF-independent, systemic lupus erythematosus-like autoimmunity. J Immunol. 2008 Jul 01; 181(1):833-41.
Stohl W, Jacob N, Quinn WJ, Cancro MP, Gao H, Putterman C, Gao X, Pricop L, Koss MN. PMID: 18566449; PMCID: PMC2587218.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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B lymphocyte stimulator expression in patients with rheumatoid arthritis treated with tumour necrosis factor alpha antagonists: differential effects between good and poor clinical responders. Ann Rheum Dis. 2008 Aug; 67(8):1132-8.
La DT, Collins CE, Yang HT, Migone TS, Stohl W. PMID: 17967830.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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B cell depletion therapy in systemic lupus erythematosus: relationships among serum B lymphocyte stimulator levels, autoantibody profile and clinical response. Ann Rheum Dis. 2008 Jul; 67(7):1011-6.
Cambridge G, Isenberg DA, Edwards JC, Leandro MJ, Migone TS, Teodorescu M, Stohl W. PMID: 17962238.
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PubMed Mentions:
68 Fields:
Translation:
HumansCellsCTClinical Trials
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New and promising treatments for rheumatoid arthritis. Am J Orthop (Belle Mead NJ). 2007 Jul; 36(7 Suppl):18-23.
Looney RJ, Stohl W. PMID: 17694190.
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PubMed Mentions: Fields:
Translation:
Humans
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Therapeutic targeting of B lymphocyte stimulator (BLyS) in the rheumatic diseases. Endocr Metab Immune Disord Drug Targets. 2006 Dec; 6(4):351-8.
Stohl W. PMID: 17214581.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
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Patients with inflammatory arthritic diseases harbor elevated serum and synovial fluid levels of free and immune-complexed glucose-6-phosphate isomerase (G6PI). Biochem Biophys Res Commun. 2006 Oct 20; 349(2):838-45.
Schaller M, Stohl W, Benoit V, Tan SM, Johansen L, Ditzel HJ. PMID: 16949042.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Paucity of clinical disease despite serological autoimmunity and kidney pathology in lupus-prone New Zealand mixed 2328 mice deficient in BAFF. J Immunol. 2006 Aug 15; 177(4):2671-80.
Jacob CO, Pricop L, Putterman C, Koss MN, Liu Y, Kollaros M, Bixler SA, Ambrose CM, Scott ML, Stohl W. PMID: 16888029; PMCID: PMC2896675.
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PubMed Mentions:
54 Fields:
Translation:
Animals
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B cell depletion therapy in systemic rheumatic diseases: different strokes for different folks? Clin Immunol. 2006 Oct; 121(1):1-12.
Stohl W, Looney RJ. PMID: 16697258.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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TGF-beta requires CTLA-4 early after T cell activation to induce FoxP3 and generate adaptive CD4+CD25+ regulatory cells. J Immunol. 2006 Mar 15; 176(6):3321-9.
Zheng SG, Wang JH, Stohl W, Kim KS, Gray JD, Horwitz DA. PMID: 16517699.
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PubMed Mentions:
116 Fields:
Translation:
AnimalsCells
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Circulating levels of B lymphocyte stimulator in patients with rheumatoid arthritis following rituximab treatment: relationships with B cell depletion, circulating antibodies, and clinical relapse. Arthritis Rheum. 2006 Mar; 54(3):723-32.
Cambridge G, Stohl W, Leandro MJ, Migone TS, Hilbert DM, Edwards JC. PMID: 16508933.
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PubMed Mentions:
100 Fields:
Translation:
HumansCells
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B lymphocyte stimulator (BLyS) isoforms in systemic lupus erythematosus: disease activity correlates better with blood leukocyte BLyS mRNA levels than with plasma BLyS protein levels. Arthritis Res Ther. 2006; 8(1):R6.
Collins CE, Gavin AL, Migone TS, Hilbert DM, Nemazee D, Stohl W. PMID: 16356193; PMCID: PMC1526545.
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PubMed Mentions:
49 Fields:
Translation:
Humans
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Humoral autoimmunity in mice overexpressing B cell surface CD19: vital role for MHC class II. Clin Immunol. 2005 Sep; 116(3):257-64.
Stohl W, Xu D, Kim KS, Tedder TF, Sato S. PMID: 15963762.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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BAFF overexpression and accelerated glomerular disease in mice with an incomplete genetic predisposition to systemic lupus erythematosus. Arthritis Rheum. 2005 Jul; 52(7):2080-91.
Stohl W, Xu D, Kim KS, Koss MN, Jorgensen TN, Deocharan B, Metzger TE, Bixler SA, Hong YS, Ambrose CM, Mackay F, Morel L, Putterman C, Kotzin BL, Kalled SL. PMID: 15986357.
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PubMed Mentions:
47 Fields:
Translation:
AnimalsCells
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BlySfulness does not equal blissfulness in systemic lupus erythematosus: a therapeutic role for BLyS antagonists. Curr Dir Autoimmun. 2005; 8:289-304.
Stohl W. PMID: 15564726.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimals
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Increased CXCL8 (IL-8) expression in Multiple Sclerosis. J Neuroimmunol. 2004 Oct; 155(1-2):161-71.
Lund BT, Ashikian N, Ta HQ, Chakryan Y, Manoukian K, Groshen S, Gilmore W, Cheema GS, Stohl W, Burnett ME, Ko D, Kachuck NJ, Weiner LP. PMID: 15342208.
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PubMed Mentions:
47 Fields:
Translation:
HumansCells
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Raised levels of anti-glucose-6-phosphate isomerase IgG in serum and synovial fluid from patients with inflammatory arthritis. Ann Rheum Dis. 2005 May; 64(5):743-9.
Schaller M, Stohl W, Tan SM, Benoit VM, Hilbert DM, Ditzel HJ. PMID: 15458959; PMCID: PMC1755497.
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PubMed Mentions:
14 Fields:
Translation:
Humans
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Inverse association between circulating APRIL levels and serological and clinical disease activity in patients with systemic lupus erythematosus. Ann Rheum Dis. 2004 Sep; 63(9):1096-103.
Stohl W, Metyas S, Tan SM, Cheema GS, Oamar B, Roschke V, Wu Y, Baker KP, Hilbert DM. PMID: 15308519; PMCID: PMC1755113.
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PubMed Mentions:
27 Fields:
Translation:
Humans
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Dichotomous effects of complete versus partial class II major histocompatibility complex deficiency on circulating autoantibody levels in autoimmune-prone mice. Arthritis Rheum. 2004 Jul; 50(7):2227-39.
Stohl W, Xu D, Metzger TE, Kim KS, Morel L, Kotzin BL. PMID: 15248222.
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PubMed Mentions:
5 Fields:
Translation:
Animals
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Targeting B lymphocyte stimulator in systemic lupus erythematosus and other autoimmune rheumatic disorders. Expert Opin Ther Targets. 2004 Jun; 8(3):177-89.
Stohl W. PMID: 15161425.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
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MHC class II-independent and -dependent T cell expansion and B cell hyperactivity in vivo in mice deficient in CD152 (CTLA-4). Int Immunol. 2004 Jul; 16(7):895-904.
Stohl W, Xu D, Kim KS, David CS, Allison JP. PMID: 15136557.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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A therapeutic role for BLyS antagonists. Lupus. 2004; 13(5):317-22.
Stohl W. PMID: 15230285.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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B lymphocyte stimulator overexpression in patients with systemic lupus erythematosus: longitudinal observations. Arthritis Rheum. 2003 Dec; 48(12):3475-86.
Stohl W, Metyas S, Tan SM, Cheema GS, Oamar B, Xu D, Roschke V, Wu Y, Baker KP, Hilbert DM. PMID: 14673998.
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PubMed Mentions:
163 Fields:
Translation:
HumansCells
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In vitro and in vivo T cell oligoclonality following chronic stimulation with staphylococcal superantigens. Clin Immunol. 2003 Sep; 108(3):182-9.
Kim KS, Jacob N, Stohl W. PMID: 14499241.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Local production of B lymphocyte stimulator protein and APRIL in arthritic joints of patients with inflammatory arthritis. Arthritis Rheum. 2003 Apr; 48(4):982-92.
Tan SM, Xu D, Roschke V, Perry JW, Arkfeld DG, Ehresmann GR, Migone TS, Hilbert DM, Stohl W. PMID: 12687540.
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PubMed Mentions:
54 Fields:
Translation:
HumansCells
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SLE--systemic lupus erythematosus: a BLySful, yet BAFFling, disorder. Arthritis Res Ther. 2003; 5(3):136-8.
Stohl W. PMID: 12723979; PMCID: PMC165050.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimals
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BLyS and APRIL form biologically active heterotrimers that are expressed in patients with systemic immune-based rheumatic diseases. J Immunol. 2002 Oct 15; 169(8):4314-21.
Roschke V, Sosnovtseva S, Ward CD, Hong JS, Smith R, Albert V, Stohl W, Baker KP, Ullrich S, Nardelli B, Hilbert DM, Migone TS. PMID: 12370363.
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PubMed Mentions:
73 Fields:
Translation:
HumansAnimalsCells
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Systemic lupus erythematosus: a blissless disease of too much BLyS (B lymphocyte stimulator) protein. Curr Opin Rheumatol. 2002 Sep; 14(5):522-8.
Stohl W. PMID: 12192248.
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PubMed Mentions:
2 Translation:
HumansAnimalsCells
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B lymphocyte stimulator protein-associated increase in circulating autoantibody levels may require CD4+ T cells: lessons from HIV-infected patients. Clin Immunol. 2002 Aug; 104(2):115-22.
Stohl W, Cheema GS, Briggs WS, Xu D, Sosnovtseva S, Roschke V, Ferrara DE, Labat K, Sattler FR, Pierangeli SS, Hilbert DM. PMID: 12165272.
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PubMed Mentions:
18 Fields:
Translation:
HumansCells
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B lymphocyte stimulator protein levels in systemic lupus erythematosus and other diseases. Curr Rheumatol Rep. 2002 Aug; 4(4):345-50.
Stohl W. PMID: 12126587.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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In vivo staphylococcal superantigen-driven polyclonal Ig responses in mice: dependence upon CD4(+) cells and human MHC class II. Int Immunol. 2001 Oct; 13(10):1291-300.
Stohl W, Xu D, Zang S, Kim KS, Li L, Hanson JA, Stohlman SA, David CS, Jacob CO. PMID: 11581174.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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Cell cycle phase-specific survival of CD95 ligand-challenged Jurkat cells: upregulation of heat-shock response. Cell Immunol. 2001 Jul 10; 211(1):21-9.
Parr TB, Hofman FM, Kiener PA, Stohl W. PMID: 11585384.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases. Arthritis Rheum. 2001 Jun; 44(6):1313-9.
Cheema GS, Roschke V, Hilbert DM, Stohl W. PMID: 11407690.
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PubMed Mentions:
239 Fields:
Translation:
HumansAnimals
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Promotion of activated human B cell apoptosis and inhibition of Ig production by soluble CD95 ligand: CD95-based downregulation of Ig production need not culminate in activated B cell death. Cell Immunol. 2000 Jul 10; 203(1):1-11.
Stohl W, Xu D, Starling GC, Casali P, Kiener PA. PMID: 10915556.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Impaired cytotoxic T lymphocyte activity in systemic lupus erythematosus following in vitro polyclonal T cell stimulation: a contributory role for non-T cells. Lupus. 1999; 8(4):293-9.
Stohl W, Hamilton AS, Deapen DM, Mack TM, Horwitz DA. PMID: 10413208.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Superantigen-driven, CD8+ T cell-mediated down-regulation: CD95 (Fas)-dependent down-regulation of human Ig responses despite CD95-independent killing of activated B cells. J Immunol. 1998 Oct 01; 161(7):3292-8.
Stohl W, Lynch DH, Starling GC, Kiener PA. PMID: 9759844.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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CD95 (Fas)-based, superantigen-dependent, CD4+ T cell-mediated down-regulation of human in vitro immunoglobulin responses. J Immunol. 1998 Jun 01; 160(11):5231-8.
Stohl W, Elliott JE, Lynch DH, Kiener PA. PMID: 9605118.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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TCR AV24 gene expression in double negative T cells in systemic lupus erythematosus. Lupus. 1998; 7(8):565-8.
Sumida T, Maeda T, Taniguchi M, Nishioka K, Stohl W. PMID: 9863902.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Impaired nonrestricted cytolytic activity in systemic lupus erythematosus: involvement of a pathway independent of Fas, tumor necrosis factor, and extracellular ATP that is associated with little detectable perforin. Arthritis Rheum. 1997 Jun; 40(6):1130-7.
Stohl W, Elliott JE, Li L, Podack ER, Lynch DH, Jacob CO. PMID: 9182924.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Impaired recovery and cytolytic function of CD56+ T and non-T cells in systemic lupus erythematosus following in vitro polyclonal T cell stimulation. Studies in unselected patients and monozygotic disease-discordant twins. Arthritis Rheum. 1996 Nov; 39(11):1840-51.
Stohl W, Elliott JE, Hamilton AS, Deapen DM, Mack TM, Horwitz DA. PMID: 8912506.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Treatment of rheumatoid arthritis. N Engl J Med. 1996 Sep 12; 335(11):821-2; author reply 822-3.
Stohl W, Arkfeld DG. PMID: 8778593.
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Translation:
Humans
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In vitro inhibition by intravenous immunoglobulin of human T cell-dependent B cell differentiation induced by staphylococcal superantigens. Clin Immunol Immunopathol. 1996 May; 79(2):122-33.
Stohl W, Elliot JE. PMID: 8620618.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Differential human T cell-dependent B cell differentiation induced by staphylococcal superantigens (SAg). Regulatory role for SAg-dependent B cell cytolysis. J Immunol. 1995 Aug 15; 155(4):1838-50.
Stohl W, Elliott JE. PMID: 7636237.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Impaired polyclonal T cell cytolytic activity. A possible risk factor for systemic lupus erythematosus. Arthritis Rheum. 1995 Apr; 38(4):506-16.
Stohl W. PMID: 7718004.
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PubMed Mentions:
20 Fields:
Translation:
HumansCells
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Enhancing effects of interleukin 2-treated peripheral blood mononuclear cells on subsequent B cell differentiation. Cell Immunol. 1994 Sep; 157(2):381-92.
Stohl W, Elliott JE, Wang H, Lin YG, Horwitz DA. PMID: 8069923.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Polyclonal in vitro T cell proliferation and T cell-dependent B cell differentiation supported by activated autologous B cells. Clin Immunol Immunopathol. 1994 Jul; 72(1):44-52.
Stohl W, Elliott JE, Linsley PS. PMID: 7517348.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Human T cell-dependent B cell differentiation induced by staphylococcal superantigens. J Immunol. 1994 Jul 01; 153(1):117-27.
Stohl W, Elliott JE, Linsley PS. PMID: 7515921.
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PubMed Mentions:
18 Fields:
Translation:
HumansCells
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Stimulation of human peripheral blood mononuclear cells with anti-CD3 monoclonal antibody vs IL2: disparate effects on T cell-dependent B cell differentiation despite similar effects on generation of unrestricted cytolytic activity. Clin Immunol Immunopathol. 1992 Oct; 65(1):30-8.
Stohl W, Elliott JE. PMID: 1395122.
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Translation:
HumansCells
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Impaired generation of polyclonal T cell-mediated cytolytic activity despite normal polyclonal T cell proliferation in systemic lupus erythematosus. Clin Immunol Immunopathol. 1992 May; 63(2):163-72.
Stohl W. PMID: 1611718.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Induction of human T cell proliferation by a monoclonal antibody to CD5. J Immunol. 1991 Jan 01; 146(1):47-52.
Spertini F, Stohl W, Ramesh N, Moody C, Geha RS. PMID: 1701800.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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Inhibition by anti-CD2 monoclonal antibodies of anti-CD3-induced T cell-dependent B cell activation. Cell Immunol. 1990 Oct 15; 130(2):257-70.
Stohl W, Crow MK. PMID: 1976440.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Differential CD3/T cell antigen receptor-mediated IL-2 production in jurkat T cells. Dissociation of IL-2 response from total inositol phosphate and calcium responses. J Immunol. 1990 Aug 15; 145(4):1078-87.
Stohl W, Hofman FM, Gray JD. PMID: 2143206.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Generation of cytolytic activity with anti-CD3 monoclonal antibodies involves both IL-2-independent and -dependent components. J Immunol. 1990 May 15; 144(10):3718-25.
Stohl W, Tovar Z, Talal N. PMID: 2139672.
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HumansCells
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A novel role for accessory cells in T cell-dependent B cell differentiation. Cell Immunol. 1990 May; 127(2):458-69.
Shiba K, Stohl W, Gray JD, Horwitz DA. PMID: 2328534.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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A functionally unique anti-CD3 monoclonal antibody cross-reactive with basal keratinocytes. Cell Immunol. 1989 Jul; 121(2):247-60.
Stohl W, Gottlieb AB, Reeves WH. PMID: 2472221.
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HumansAnimalsCells
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Human peripheral blood T helper cell-induced B cell activation results in B cell surface expression of the CD23 (BLAST-2) antigen. Cell Immunol. 1989 Jun; 121(1):99-112.
Crow MK, Kushner B, Jover JA, Friedman SM, Mechanic SE, Stohl W. PMID: 2524281.
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6 Fields:
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HumansCells
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Inhibitory effects of anti-CD2 monoclonal antibodies on interleukin 2 production and interleukin 2 receptor expression in anti-CD3-induced T cell activation. Cell Immunol. 1989 May; 120(2):351-65.
Stohl W, Linker-Israeli M. PMID: 2566387.
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1 Fields:
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HumansCells
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Characterization of lymphokines mediating B cell growth and differentiation from monoclonal anti-CD3 antibody-stimulated T cells. J Immunol. 1989 Apr 01; 142(7):2343-51.
Sherris D, Stohl W, Mayer L. PMID: 2538506.
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2 Fields:
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HumansCells
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Feedback inhibition of B cell differentiation by monomeric immunoglobulin. Int Rev Immunol. 1989; 5(2):189-95.
Mayer L, Stohl W, Cunningham-Rundles C. PMID: 8691052.
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3 Fields:
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HumansCells
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In vitro induction of T cell-dependent B cell differentiation in patients with common varied immunodeficiency. Clin Immunol Immunopathol. 1988 Nov; 49(2):273-82.
Stohl W, Cunningham-Rundles C, Mayer L. PMID: 3262471.
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4 Fields:
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HumansCells
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Differential immunomodulation by anti-CD2 monoclonal antibodies of anti-CD3-induced T cell activation: dependence upon the individual anti-CD3 monoclonal antibody used for activation. Cell Immunol. 1988 Oct 01; 116(1):73-85.
Stohl W, Posnett DN, Chiorazzi N. PMID: 2458845.
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1 Fields:
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HumansCells
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Correlation between systemic lupus erythematosus and T4 epitope phenotype. Arthritis Rheum. 1987 Dec; 30(12):1412-5.
Stohl W, Singer JZ. PMID: 2449224.
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HumansCells
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Inhibition of T cell-dependent human B cell proliferation and B cell differentiation by polyspecific monomeric IgG. Clin Exp Immunol. 1987 Dec; 70(3):649-57.
Stohl W, Mayer L. PMID: 3501745; PMCID: PMC1542192.
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1 Fields:
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HumansCells
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Induction of T cell-dependent B cell differentiation by anti-CD3 monoclonal antibodies. J Immunol. 1987 Mar 15; 138(6):1667-73.
Stohl W, Posnett DN, Chiorazzi N. PMID: 2950165.
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9 Fields:
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HumansCells
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Modulation of the immune response by immunoglobulin for intravenous use. II. Inhibitory effects of sera from treated patients. Clin Immunol Immunopathol. 1986 Nov; 41(2):273-80.
Stohl W, Cunningham-Rundles C, Thompson C, Mayer L. PMID: 2429797.
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3 Fields:
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HumansCells
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Cellular mechanisms in the in vitro inhibition of pokeweed mitogen-induced B cell differentiation by immunoglobulin for intravenous use. J Immunol. 1986 Jun 15; 136(12):4407-13.
Stohl W. PMID: 2940294.
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17 Fields:
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HumansCells
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Modulation of the immune response by immunoglobulin for intravenous use. I. Inhibition of pokeweed mitogen-induced B cell differentiation. Clin Exp Immunol. 1985 Oct; 62(1):200-7.
Stohl W. PMID: 3933869; PMCID: PMC1577410.
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6 Fields:
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HumansCells
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Systemic lupus erythematosus with deficiency of the T4 epitope on T helper/inducer cells. N Engl J Med. 1985 Jun 27; 312(26):1671-8.
Stohl W, Crow MK, Kunkel HG. PMID: 2582253.
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4 Fields:
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HumansCells
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Heterogeneity in expression of the T4 epitope in black individuals. Scand J Immunol. 1984 Sep; 20(3):273-8.
Stohl W, Kunkel HG. PMID: 6208600.
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6 Fields:
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Humans
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Deficient OKT4 epitope on helper T cells in a patient with SLE: confusion with AIDS. N Engl J Med. 1984 06 07; 310(23):1531.
Stohl W. PMID: 6232461.
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4 Fields:
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HumansCells
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Detection of the precursor and effector cells of experimental allergic encephalomyelitis in the thoracic duct of the rat. Cell Immunol. 1980 Sep 01; 54(2):471-7.
Stohl W, Gonatas NK. PMID: 6968247.
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AnimalsCells
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Saturday classes and rounds. N Engl J Med. 1979 May 17; 300(20):1165.
Stohl W. PMID: 431645.
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A quantitative assay for experimental allergic encephalomyelitis in the rat based on permeability of spinal cords to 125I-human gamma-globulin. J Immunol. 1979 Mar; 122(3):920-5.
Stohl W, Kaplan MS, Gonatas NK. PMID: 87421.
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6 Fields:
Translation:
HumansAnimalsPHPublic Health
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Chronic permeability of the central nervous system to mononuclear cells in experimental allergic encephalomyelitis in the Lewis rat. J Immunol. 1978 Sep; 121(3):844-50.
Stohl W, Gonatas NK. PMID: 308523.
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6 Fields:
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AnimalsCells
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Religious objections to autopsy. N Engl J Med. 1977 Oct 27; 297(17):953.
Stohl W. PMID: 904683.
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Humans
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Distribution of the thy-1 antigen in cellular and subcellular fractions of adult mouse brain. J Immunol. 1977 Aug; 119(2):422-7.
Stohl W, Gonatas NK. PMID: 69659.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells