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Arun P. Amar, MD

TitleAssociate Professor of Clinical Neurological Surgery
InstitutionUniversity of Southern California
DepartmentNeurological Surgery
AddressGNH 3300
Off Campus
Los Angeles CA 90089-9314
Phone+1 323 226 7421
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    Other Positions
    TitleDirector of Endovascular Services, Keck Hospital of Usc


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    Arun Amar, MD, is an associate professor and the Director of Endovascular Neurosurgery at the University of Southern California. He also serves as Stroke Director and Associate Chief of Neurosurgery at the LAC+USC Medical Center. He is one of the few board-certified neurosurgeons who have completed fellowship training in interventional neuroradiology as well.

    Dr. Amar graduated summa cum laude with distinction in philosophy from Yale University, where he was elected to the phi beta kappa society. He then graduated at the top of his class from the University of California San Francisco, where he earned the MD with Thesis degree based on original research he performed at their renowned Brain Tumor Research Center. Dr. Amar completed neurosurgery residency and fellowship training at USC. Concurrently, he enrolled in the PhD program in Physiology and Biophysics and was awarded a pre-doctoral fellowship from the Howard Hughes Medical Institute.

    After his training, Dr. Amar was recruited back to Yale as Director of Endovascular Neurosurgery. He subsequently worked as a faculty member at Stanford University before returning to the USC School of Medicine.

    He has been selected for inclusion in the “Best Doctors in America” database, “America’s Top Surgeons” by the Consumers Research Council of America, Marquis “Who’s Who”, Academic Keys’ “Who's Who in Medicine Higher Education”, Castle Connolly’s “America’s Top Doctors”, Pasadena magazine’s “Top Doctors”, Hollywood Reporter’s “Top Doctors” and US news and World Report “Best Doctors in America” (top 1% of neurosurgeons). He is also a Distinguished Consultant to the National Institute of Medicine and recipient of the Award of Honor of the National Institute of Medicine in the Specialty Field of Neurosurgery.

    Dr. Amar’s research and clinical interests include brain and spinal cord injury, aneurysms and vascular malformations, stroke and cerebrovascular disorders, blood-brain-barrier, brain tumors, vagus nerve stimulation, interventional neuroradiology, vertebroplasty, kyphoplasty, stem cell therapy, and gene therapy. In these and other topics, Dr. Amar has authored more than 100 publications in the neurosurgical literature. He has also edited books on spinal cord injury and interventional neuroradiology.

    Dr. Amar has led the safety committees of dozens of multicenter randomized clinical trials of cerebrovascular disorders and served on the editorial staff of numerous journals. He has also held numerous leadership positions within organized neurosurgery. He is internationally recognized for his contributions to patient care, research, and education.


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Babadjouni R, Wen T, Donoho DA, Buchanan IA, Cen SY, Friedman RA, Amar A, Russin JJ, Giannotta SL, Mack WJ, Attenello FJ. Increased Hospital Surgical Volume Reduces Rate of 30- and 90-Day Readmission After Acoustic Neuroma Surgery. Neurosurgery. 2018 Jun 08. PMID: 29889284.
      View in: PubMed
    2. Strickland BA, Rennert RC, Bakhsheshian J, Bulic S, Correa AJ, Amar A, Carey J, Russin JJ. Botulinum toxin to improve vessel graft patency in cerebral revascularization surgery: report of 3 cases. J Neurosurg. 2018 Mar 02; 1-7. PMID: 29498577.
      View in: PubMed
    3. Buchanan IA, Lee B, Amar A, Giannotta SL. In situ administration of abciximab for thrombus resolution during intracranial bypass surgery: case report. J Neurosurg. 2018 Jan 19; 1-5. PMID: 29350605.
      View in: PubMed
    4. Amar A, Sagare AP, Zhao Z, Wang Y, Nelson AR, Griffin JH, Zlokovic BV. Can adjunctive therapies augment the efficacy of endovascular thrombolysis? A potential role for activated protein C. Neuropharmacology. 2017 Sep 18. PMID: 28923278.
      View in: PubMed
    5. Dabus G, Brinjikji W, Amar A, Delgado Almandoz JE, Diaz OM, Jabbour P, Hanel R, Hui F, Kelly M, Layton KF, Miller JW, Levy EI, Moran CJ, Suh DC, Woo H, Sellar R, Hoh B, Evans A, Kallmes DF. Angiographic and clinical outcomes of balloon remodeling versus unassisted coil embolization in the ruptured aneurysm cohort of the GEL THE NEC study. J Neurointerv Surg. 2018 May; 10(5):446-450. PMID: 28821627.
      View in: PubMed
    6. Vecchiarelli K, Amar A, Emanuele D. Increasing awareness with recognition of pulsatile tinnitus for nurse practitioners in the primary care setting: A case study. J Am Assoc Nurse Pract. 2017 Sep; 29(9):506-513. PMID: 28703487.
      View in: PubMed
    7. Fredrickson VL, Russin JJ, Strickland BA, Bakhsheshian J, Amar A. Intraoperative Imaging for Vascular Lesions. Neurosurg Clin N Am. 2017 Oct; 28(4):603-613. PMID: 28917288.
      View in: PubMed
    8. Babadjouni RM, Walcott BP, Liu Q, Tenser MS, Amar A, Mack WJ. Neuroprotective delivery platforms as an adjunct to mechanical thrombectomy. Neurosurg Focus. 2017 Apr; 42(4):E4. PMID: 28366053.
      View in: PubMed
    9. Wen T, Attenello FJ, Cen SY, Khalessi AA, Kim-Tenser M, Sanossian N, Giannotta SL, Amar A, Mack WJ. Impact of the 2003 ACGME Resident Duty Hour Reform on Hospital-Acquired Conditions: A National Retrospective Analysis. J Grad Med Educ. 2017 Apr; 9(2):215-221. PMID: 28439356.
      View in: PubMed
    10. Brinjikji W, Amar A, Delgado Almandoz JE, Diaz O, Jabbour P, Hanel R, Hui F, Kelly M, Layton KD, Miller JW, Levy E, Moran C, Suh DC, Woo H, Sellar R, Ho B, Evans A, Kallmes DF. GEL THE NEC: a prospective registry evaluating the safety, ease of use, and efficacy of the HydroSoft coil as a finishing device. J Neurointerv Surg. 2018 Jan; 10(1):83-87. PMID: 28138062.
      View in: PubMed
    11. Poblete R, Zheng L, Raghavan R, Cen S, Amar A, Sanossian N, Mack W, Kim-Tenser M. Trends in Ventriculostomy-Associated Infections and Mortality in Aneurysmal Subarachnoid Hemorrhage: Data From the Nationwide Inpatient Sample. World Neurosurg. 2017 Mar; 99:599-604. PMID: 28034809.
      View in: PubMed
    12. Attenello F, Amar A, Liu C, Apuzzo ML. Theoretical Basis of Vagus Nerve Stimulation. Prog Neurol Surg. 2015; 29:20-8. PMID: 26393349.
      View in: PubMed
    13. Amar A, Griffin JH, Zlokovic BV. Combined neurothrombectomy or thrombolysis with adjunctive delivery of 3K3A-activated protein C in acute ischemic stroke. Front Cell Neurosci. 2015; 9:344. PMID: 26388732; PMCID: PMC4556986.
    14. Russin JJ, Kramer DR, Thomas D, Hasson D, Liu CY, Amar A, Mack WJ, Giannotta SL. The importance of preoperative diagnosis of blister aneurysms. J Clin Neurosci. 2015 Sep; 22(9):1408-12. PMID: 25960141.
      View in: PubMed
    15. Attenello FJ, Wen T, Cen SY, Ng A, Kim-Tenser M, Sanossian N, Amar A, Mack WJ. Incidence of "never events" among weekend admissions versus weekday admissions to US hospitals: national analysis. BMJ. 2015 Apr 15; 350:h1460. PMID: 25876878; PMCID: PMC4398994.
    16. Attenello FJ, Ng A, Wen T, Cen SY, Sanossian N, Amar A, Zada G, Krieger MD, McComb JG, Mack WJ. Racial and socioeconomic disparities in outcomes following pediatric cerebrospinal fluid shunt procedures. J Neurosurg Pediatr. 2015 Jun; 15(6):560-6. PMID: 25791773.
      View in: PubMed
    17. Pouw AE, Rabin RL, Karanjia R, Bababeygy SR, Amar A, Sadun AA. Angioarchitectural evolution of clival dural arteriovenous fistulas in two patients. Case Rep Ophthalmol. 2015 Jan-Apr; 6(1):93-100. PMID: 25873894; PMCID: PMC4386113.
    18. Attenello FJ, Reid P, Wen T, Cen S, Kim-Tenser M, Sanossian N, Russin J, Amar A, Giannotta S, Mack WJ, Tenser M. Evaluation of time to aneurysm treatment following subarachnoid hemorrhage: comparison of patients treated with clipping versus coiling. J Neurointerv Surg. 2016 Apr; 8(4):373-7. PMID: 25765950.
      View in: PubMed
    19. Torbey MT, Bösel J, Rhoney DH, Rincon F, Staykov D, Amar A, Varelas PN, Jüttler E, Olson D, Huttner HB, Zweckberger K, Sheth KN, Dohmen C, Brambrink AM, Mayer SA, Zaidat OO, Hacke W, Schwab S. Evidence-based guidelines for the management of large hemispheric infarction : a statement for health care professionals from the Neurocritical Care Society and the German Society for Neuro-intensive Care and Emergency Medicine. Neurocrit Care. 2015 Feb; 22(1):146-64. PMID: 25605626.
      View in: PubMed
    20. Attenello FJ, Wang K, Wen T, Cen SY, Kim-Tenser M, Amar A, Sanossian N, Giannotta SL, Mack WJ. Health disparities in time to aneurysm clipping/coiling among aneurysmal subarachnoid hemorrhage patients: a national study. World Neurosurg. 2014 Dec; 82(6):1071-6. PMID: 25175276.
      View in: PubMed
    21. Lee B, Mehta VA, Mack WJ, Tenser MS, Amar A. Balloon-assisted transarterial embolization of type 1 spinal dural arteriovenous fistula. Neurosurg Focus. 2014 Jul; 37(1 Suppl):1. PMID: 24983724.
      View in: PubMed
    22. Wen T, Attenello FJ, He S, Cen Y, Kim-Tenser MA, Sanossian N, Amar A, Mack WJ. Racial and socioeconomic disparities in incidence of hospital-acquired complications following cerebrovascular procedures. Neurosurgery. 2014 Jul; 75(1):43-50. PMID: 24662507.
      View in: PubMed
    23. Lee B, Mehta VA, Amar A, Tenser MS, Mack WJ. Transarterial embolization of an anterior fossa cranial base dural arteriovenous fistula. Neurosurg Focus. 2014 Jul; 37(1 Suppl):1. PMID: 24983725.
      View in: PubMed
    24. Wen T, He S, Attenello F, Cen SY, Kim-Tenser M, Adamczyk P, Amar A, Sanossian N, Mack WJ. The impact of patient age and comorbidities on the occurrence of "never events" in cerebrovascular surgery: an analysis of the Nationwide Inpatient Sample. J Neurosurg. 2014 Sep; 121(3):580-6. PMID: 24972123.
      View in: PubMed
    25. Ferreira R, Santos T, Amar A, Gong A, Chen TC, Tahara SM, Giannotta SL, Hofman FM. Argonaute-2 promotes miR-18a entry in human brain endothelial cells. J Am Heart Assoc. 2014 May 16; 3(3):e000968. PMID: 24837588; PMCID: PMC4309089.
    26. Ferreira R, Santos T, Amar A, Tahara SM, Chen TC, Giannotta SL, Hofman FM. MicroRNA-18a improves human cerebral arteriovenous malformation endothelial cell function. Stroke. 2014 Jan; 45(1):293-7. PMID: 24203843.
      View in: PubMed
    27. He S, Russin JJ, Adamczyk P, Giannotta SL, Amar A, Mack WJ. A persistent primitive hypoglossal artery arising from the external carotid artery associated with subarachnoid hemorrhage. World Neurosurg. 2014 Jul-Aug; 82(1-2):239.e1-3. PMID: 23851212.
      View in: PubMed
    28. Kramer DR, Winer JL, Pease BA, Amar A, Mack WJ. Cerebral vasospasm in traumatic brain injury. Neurol Res Int. 2013; 2013:415813. PMID: 23862062; PMCID: PMC3703898.
    29. Attenello FJ, Adamczyk P, Wen G, He S, Zhang K, Russin JJ, Sanossian N, Amar A, Mack WJ. Racial and socioeconomic disparities in access to mechanical revascularization procedures for acute ischemic stroke. J Stroke Cerebrovasc Dis. 2014 Feb; 23(2):327-34. PMID: 23680690; PMCID: PMC4467551.
    30. Adamczyk P, He S, Amar A, Mack WJ. Medical Management of Cerebral Vasospasm following Aneurysmal Subarachnoid Hemorrhage: A Review of Current and Emerging Therapeutic Interventions. Neurol Res Int. 2013; 2013:462491. PMID: 23691312; PMCID: PMC3649802.
    31. Tuchman A, Khalessi AA, Attenello FJ, Amar A, Zada G. Delayed cavernous carotid artery pseudoaneurysm caused by absorbable plate following transsphenoidal surgery: case report and review of the literature. J Neurol Surg Rep. 2013 Jun; 74(1):10-6. PMID: 23943714; PMCID: PMC3713556.
    32. Mehta V, Russin J, Spirtos A, He S, Adamczyk P, Amar A, Mack WJ. Matrix Metalloproteinases in Cerebral Vasospasm following Aneurysmal Subarachnoid Hemorrhage. Neurol Res Int. 2013; 2013:943761. PMID: 23691315; PMCID: PMC3649803.
    33. Amar A. Neurosurgery in India: past as prologue. World Neurosurg. 2013 May-Jun; 79(5-6):613-4. PMID: 23507299.
      View in: PubMed
    34. Mills JN, Mehta V, Russin J, Amar A, Rajamohan A, Mack WJ. Advanced imaging modalities in the detection of cerebral vasospasm. Neurol Res Int. 2013; 2013:415960. PMID: 23476766; PMCID: PMC3580927.
    35. Russin JJ, Attenello FJ, Amar A, Liu CY, Apuzzo ML, Hsieh PC. Computed tomography for clearance of cervical spine injury in the unevaluable patient. World Neurosurg. 2013 Sep-Oct; 80(3-4):405-13. PMID: 23321374.
      View in: PubMed
    36. Adamczyk P, Attenello F, Wen G, He S, Russin J, Sanossian N, Amar A, Mack WJ. Mechanical thrombectomy in acute stroke: utilization variances and impact of procedural volume on inpatient mortality. J Stroke Cerebrovasc Dis. 2013 Nov; 22(8):1263-9. PMID: 23017430; PMCID: PMC4085991.
    37. Adamczyk P, Amar A, Mack WJ, Larsen DW. Recurrence of "cured" dural arteriovenous fistulas after Onyx embolization. Neurosurg Focus. 2012 May; 32(5):E12. PMID: 22537121; PMCID: PMC4085989.
    38. Amar A, Newell DW. Vascular fistulas of the brain and spinal cord. Neurosurg Focus. 2012 May; 32(5):Introduction. PMID: 22537136.
      View in: PubMed
    39. Amar A. Controversies in the neurosurgical management of cerebellar hemorrhage and infarction. Neurosurg Focus. 2012 Apr; 32(4):E1. PMID: 22463111.
      View in: PubMed
    40. Tenser MS, Amar A, Mack WJ. Mechanical thrombectomy for acute ischemic stroke using the MERCI retriever and penumbra aspiration systems. World Neurosurg. 2011 Dec; 76(6 Suppl):S16-23. PMID: 22182267.
      View in: PubMed
    41. Amar A. Brain and vascular imaging of acute stroke. World Neurosurg. 2011 Dec; 76(6 Suppl):S3-8. PMID: 22182269.
      View in: PubMed
    42. Yashar P, Amar A, Giannotta SL, Yu C, Pagnini PG, Liu CY, Apuzzo ML. Cerebral arteriovenous malformations: issues of the interplay between stereotactic radiosurgery and endovascular surgical therapy. World Neurosurg. 2011 May-Jun; 75(5-6):638-47. PMID: 21704930.
      View in: PubMed
    43. Levy ML, Levy KM, Hoff D, Amar A, Park MS, Conklin JM, Baird L, Apuzzo ML. Vagus nerve stimulation therapy in patients with autism spectrum disorder and intractable epilepsy: results from the vagus nerve stimulation therapy patient outcome registry. J Neurosurg Pediatr. 2010 Jun; 5(6):595-602. PMID: 20515333.
      View in: PubMed
    44. Hoh DJ, Hoh BL, Amar A, Wang MY. Shape memory alloys: metallurgy, biocompatibility, and biomechanics for neurosurgical applications. Neurosurgery. 2009 May; 64(5 Suppl 2):199-214; discussion 214-5. PMID: 19404101.
      View in: PubMed
    45. Heller AC, Amar A, Liu CY, Apuzzo ML. Surgery of the mind and mood: a mosaic of issues in time and evolution. Neurosurgery. 2008 Jun; 62(6 Suppl 3):921-40. PMID: 18695579.
      View in: PubMed
    46. Amar A, Apuzzo ML, Liu CY. Vagus nerve stimulation therapy after failed cranial surgery for intractable epilepsy: results from the vagus nerve stimulation therapy patient outcome registry. Neurosurgery. 2008 Feb; 62 Suppl 2:506-13. PMID: 18596453.
      View in: PubMed
    47. Amar A. Vagus nerve stimulation for the treatment of intractable epilepsy. Expert Rev Neurother. 2007 Dec; 7(12):1763-73. PMID: 18052768.
      View in: PubMed
    48. Amar A, Teitelbaum GP, Larsen DW. A novel technique and new grading scale for the embolization of cerebral vascular malformations. Neurosurgery. 2006 Nov; 59(5 Suppl 3):S158-62; discussion S3-13. PMID: 17053599.
      View in: PubMed
    49. Heller AC, Amar A, Liu CY, Apuzzo ML. Surgery of the mind and mood: a mosaic of issues in time and evolution. Neurosurgery. 2006 Oct; 59(4):720-33; discussion 733-9. PMID: 17038938.
      View in: PubMed
    50. Ozturk AK, Nahed BV, Bydon M, Bilguvar K, Goksu E, Bademci G, Guclu B, Johnson MH, Amar A, Lifton RP, Gunel M. Molecular genetic analysis of two large kindreds with intracranial aneurysms demonstrates linkage to 11q24-25 and 14q23-31. Stroke. 2006 Apr; 37(4):1021-7. PMID: 16497978.
      View in: PubMed
    51. Nicholls TP, Shoemaker WC, Wo CC, Gruen JP, Amar A, Dang AB. Survival, hemodynamics, and tissue oxygenation after head trauma. J Am Coll Surg. 2006 Jan; 202(1):120-30. PMID: 16377505.
      View in: PubMed
    52. Nahed BV, DiLuna ML, Morgan T, Ocal E, Hawkins AA, Ozduman K, Kahle KT, Chamberlain A, Amar A, Gunel M. Hypertension, age, and location predict rupture of small intracranial aneurysms. Neurosurgery. 2005 Oct; 57(4):676-83; discussion 676-83. PMID: 16239879.
      View in: PubMed
    53. Aryan HE, Amar A, Ozgur BM, Levy ML. Gunshot wounds to the spine in adolescents. Neurosurgery. 2005 Oct; 57(4):748-52; discussion 748-52. PMID: 16239887.
      View in: PubMed
    54. Amar A, Larsen DW, Teitelbaum GP. Percutaneous spinal interventions. Neurosurg Clin N Am. 2005 Jul; 16(3):561-8, vii. PMID: 15990045.
      View in: PubMed
    55. Chakrabarti I, Amar A, Couldwell W, Weiss MH. Long-term neurological, visual, and endocrine outcomes following transnasal resection of craniopharyngioma. J Neurosurg. 2005 Apr; 102(4):650-7. PMID: 15871507.
      View in: PubMed
    56. Amar A, Apuzzo ML, Liu CY. Vagus nerve stimulation therapy after failed cranial surgery for intractable epilepsy: results from the vagus nerve stimulation therapy patient outcome registry. Neurosurgery. 2004 Nov; 55(5):1086-93. PMID: 15509315.
      View in: PubMed
    57. Levy ML, Meltzer HS, Hughes S, Aryan HE, Yoo K, Amar A. Hydrocephalus in children with middle fossa arachnoid cysts. J Neurosurg. 2004 Aug; 101(1 Suppl):25-31. PMID: 16206968.
      View in: PubMed
    58. Amar A, Larsen DW, Teitelbaum GP. Use of a screw-syringe injector for cement delivery during kyphoplasty: technical report. Neurosurgery. 2003 Aug; 53(2):380-2; discussion 383. PMID: 12925255.
      View in: PubMed
    59. Amar A, Aryan HE, Meltzer HS, Levy ML. Neonatal subgaleal hematoma causing brain compression: report of two cases and review of the literature. Neurosurgery. 2003 Jun; 52(6):1470-4; discussion 1474. PMID: 12762894.
      View in: PubMed
    60. Amar A, Zlokovic BV, Apuzzo ML. Endovascular restorative neurosurgery: a novel concept for molecular and cellular therapy of the nervous system. Neurosurgery. 2003 Feb; 52(2):402-12; discussion 412-3. PMID: 12535371.
      View in: PubMed
    61. Amar A, Weiss MH. Pituitary anatomy and physiology. Neurosurg Clin N Am. 2003 Jan; 14(1):11-23, v. PMID: 12690976.
      View in: PubMed
    62. Amar A, Apuzzo ML. Vagus nerve stimulation therapy for patients with persistent seizures after epilepsy surgery. Stereotact Funct Neurosurg. 2003; 80(1-4):9-13. PMID: 14745201.
      View in: PubMed
    63. Amar A, Couldwell WT, Chen JC, Weiss MH. Predictive value of serum prolactin levels measured immediately after transsphenoidal surgery. J Neurosurg. 2002 Aug; 97(2):307-14. PMID: 12186458.
      View in: PubMed
    64. Amar A, Teitelbaum GP, Giannotta SL, Larsen DW. Covered stent-graft repair of the brachiocephalic arteries: technical note. Neurosurgery. 2002 Jul; 51(1):247-52; discussion 252-3. PMID: 12182427.
      View in: PubMed
    65. Apuzzo ML, Liker MA, Amar A. Honored guest presentation: neurorestoration and the emergence of molecular and cellular neurosurgery. Clin Neurosurg. 2002; 49:274-315. PMID: 12506560.
      View in: PubMed