Christianne Norton Heck, MD, MMM
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Title(s) | Professor of Clinical Neurology |
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School | Keck School of Medicine of Usc |
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Address | HCC 3rd Floor Room 3000 Health Sciences Campus Los Angeles CA 90089-9405
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Phone | +1 323 442 5710 |
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vCard | Download vCard |
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Title(s) | Co-Director, USC Center for Neurorestoration |
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Title(s) | Medical Director, USC Comprehensive Epilepsy Center |
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Title(s) | Director of Keck NeuroConnect, Keck Medical Center of USC |
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Title(s) | Vice Chair, Clinical Affairs |
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Overview
Dr. Heck serves as the Medical Director of the USC Comprehensive Epilepsy Program at the Keck Medical Center in Los Angeles. She served as Chief of Staff at Keck Hospitals of USC from 2015-2017, and serves as Co-Director for the USC Neurorestoration Center. She is board certified in both neurology and epilepsy. She is a member of the professional advisory board of the Epilepsy Foundation and has served on the Board of Directors of the National Association of Epilepsy Centers (NAECs). From 2011-12, she served on the Institute of Medicine's Committee on the Public Health Dimensions of the Epilepsies assisting in the writing of Epilepsy Across the Spectrum: Promoting Health and Understanding. She has been a member of the Association of California Neurologists Board of Directors, where she actively participated in opinions and discussions regarding patient care and access to care within the state of California. She volunteers regularly for Hollywood Health and Society of the USC Annenberg School of Communications Norman Lear Center whose goals are the promotion and evaluation of public health topics in film and television. Her research focuses on innovative approaches to treating epilepsy, including responsive neurostimulation and paradigms for optimizing neuromodulatory therapies, vagus nerve stimulation, epilepsy surgery and Gamma Knife radiosurgery. Her expertise also includes services to minority populations as well as furthering understanding of status epilepticus, neuronal injury, memory dysfunction, brain machine interfaces and the psychosocial impact of epilepsy. She is keenly interested in quality and access to care for epilepsy patients and families across the nation.
Bibliographic
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Beta-band power modulation in the human amygdala differentiates between go/no-go responses in an arm-reaching task. J Neural Eng. 2024 Jul 16; 21(4).
Chung RS, Martin Del Campo Vera R, Sundaram S, Cavaleri J, Gilbert ZD, Leonor A, Shao X, Zhang S, Kammen A, Mason X, Heck C, Liu CY, Kellis SS, Lee B. PMID: 38959877; PMCID: PMC11369913.
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Humans
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Beta-band power classification of go/no-go arm-reaching responses in the human hippocampus. J Neural Eng. 2024 Jul 15; 21(4).
Martin Del Campo Vera R, Sundaram S, Lee R, Lee Y, Leonor A, Chung RS, Shao A, Cavaleri J, Gilbert ZD, Zhang S, Kammen A, Mason X, Heck C, Liu CY, Kellis S, Lee B. PMID: 38914073; PMCID: PMC11247508.
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Understanding the human conflict processing network: A review of the literature on direct neural recordings during performance of a modified stroop task. Neurosci Res. 2024 Apr 04.
Chung RS, Cavaleri J, Sundaram S, Gilbert ZD, Del Campo-Vera RM, Leonor A, Tang AM, Chen KH, Sebastian R, Shao A, Kammen A, Tabarsi E, Gogia AS, Mason X, Heck C, Liu CY, Kellis SS, Lee B. PMID: 38582242.
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Developing a hippocampal neural prosthetic to facilitate human memory encoding and recall of stimulus features and categories. Front Comput Neurosci. 2024; 18:1263311.
Roeder BM, She X, Dakos AS, Moore B, Wicks RT, Witcher MR, Couture DE, Laxton AW, Clary HM, Popli G, Liu C, Lee B, Heck C, Nune G, Gong H, Shaw S, Marmarelis VZ, Berger TW, Deadwyler SA, Song D, Hampson RE. PMID: 38390007; PMCID: PMC10881797.
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A review of neurophysiological effects and efficiency of waveform parameters in deep brain stimulation. Clin Neurophysiol. 2023 08; 152:93-111.
Gilbert Z, Mason X, Sebastian R, Tang AM, Martin Del Campo-Vera R, Chen KH, Leonor A, Shao A, Tabarsi E, Chung R, Sundaram S, Kammen A, Cavaleri J, Gogia AS, Heck C, Nune G, Liu CY, Kellis SS, Lee B. PMID: 37208270.
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1 Fields:
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Corrigendum: Patterned hippocampal stimulation facilitates memory in patients with a history of head impact and/or brain injury. Front Hum Neurosci. 2022; 16:1039221.
Roeder BM, Riley MR, She X, Dakos AS, Robinson BS, Moore BJ, Couture DE, Laxton AW, Popli G, Munger Clary HM, Sam M, Heck C, Nune G, Lee B, Liu C, Shaw S, Gong H, Marmarelis VZ, Berger TW, Deadwyler SA, Song D, Hampson RE. PMID: 36277045; PMCID: PMC9583523.
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Patterned Hippocampal Stimulation Facilitates Memory in Patients With a History of Head Impact and/or Brain Injury. Front Hum Neurosci. 2022; 16:933401.
Roeder BM, Riley MR, She X, Dakos AS, Robinson BS, Moore BJ, Couture DE, Laxton AW, Popli G, Clary HM, Sam M, Heck C, Nune G, Lee B, Liu C, Shaw S, Gong H, Marmarelis VZ, Berger TW, Deadwyler SA, Song D, Hampson RE. PMID: 35959242; PMCID: PMC9358788.
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2
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Baseline hippocampal beta band power is lower in the presence of movement uncertainty. J Neural Eng. 2022 07 22; 19(4).
Gilbert ZD, Martin Del Campo-Vera R, Tang AM, Chen KH, Sebastian R, Shao A, Tabarsi E, Chung RS, Leonor A, Sundaram S, Heck C, Nune G, Liu CY, Kellis S, Lee B. PMID: 35803209; PMCID: PMC9376116.
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Humans
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Altered adult neurogenesis and gliogenesis in patients with mesial temporal lobe epilepsy. Nat Neurosci. 2022 04; 25(4):493-503.
Ammothumkandy A, Ravina K, Wolseley V, Tartt AN, Yu PN, Corona L, Zhang N, Nune G, Kalayjian L, Mann JJ, Rosoklija GB, Arango V, Dwork AJ, Lee B, Smith JAD, Song D, Berger TW, Heck C, Chow RH, Boldrini M, Liu CY, Russin JJ, Bonaguidi MA. PMID: 35383330; PMCID: PMC9097543.
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23 Fields:
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Humans
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Neuroanatomic Markers of Posttraumatic Epilepsy Based on MR Imaging and Machine Learning. AJNR Am J Neuroradiol. 2022 03; 43(3):347-353.
Akrami H, Leahy RM, Irimia A, Kim PE, Heck CN, Joshi AA. PMID: 35210268; PMCID: PMC8910810.
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1 Fields:
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Humans
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A sparse multiscale nonlinear autoregressive model for seizure prediction. J Neural Eng. 2021 02 26; 18(2).
Yu PN, Liu CY, Heck CN, Berger TW, Song D. PMID: 33470981.
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1 Fields:
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HumansAnimals
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Gray Matter Atrophy: The Impacts of Resective Surgery and Vagus Nerve Stimulation in Drug-Resistant Epilepsy. World Neurosurg. 2021 05; 149:e535-e545.
Lam J, Cabeen RP, Tanna R, Navarro L, Heck CN, Liu CY, Lee B, Russin JR, Toga AW, Lee DJ. PMID: 33549931; PMCID: PMC8121141.
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3 Fields:
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Humans
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Nine-year prospective efficacy and safety of brain-responsive neurostimulation for focal epilepsy. Neurology. 2020 09 01; 95(9):e1244-e1256.
Nair DR, Laxer KD, Weber PB, Murro AM, Park YD, Barkley GL, Smith BJ, Gwinn RP, Doherty MJ, Noe KH, Zimmerman RS, Bergey GK, Anderson WS, Heck C, Liu CY, Lee RW, Sadler T, Duckrow RB, Hirsch LJ, Wharen RE, Tatum W, Srinivasan S, McKhann GM, Agostini MA, Alexopoulos AV, Jobst BC, Roberts DW, Salanova V, Witt TC, Cash SS, Cole AJ, Worrell GA, Lundstrom BN, Edwards JC, Halford JJ, Spencer DC, Ernst L, Skidmore CT, Sperling MR, Miller I, Geller EB, Berg MJ, Fessler AJ, Rutecki P, Goldman AM, Mizrahi EM, Gross RE, Shields DC, Schwartz TH, Labar DR, Fountain NB, Elias WJ, Olejniczak PW, Villemarette-Pittman NR, Eisenschenk S, Roper SN, Boggs JG, Courtney TA, Sun FT, Seale CG, Miller KL, Skarpaas TL, Morrell MJ, RNS System LTT Study. PMID: 32690786; PMCID: PMC7538230.
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125 Fields:
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Humans
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Real-world experience with direct brain-responsive neurostimulation for focal onset seizures. Epilepsia. 2020 08; 61(8):1749-1757.
Razavi B, Rao VR, Lin C, Bujarski KA, Patra SE, Burdette DE, Geller EB, Brown MM, Johnson EA, Drees C, Chang EF, Greenwood JE, Heck CN, Jobst BC, Gwinn RP, Warner NM, Halpern CH. PMID: 32658325; PMCID: PMC7496294.
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36 Fields:
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Humans
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Mesial temporal resection following long-term ambulatory intracranial EEG monitoring with a direct brain-responsive neurostimulation system. Epilepsia. 2020 03; 61(3):408-420.
Hirsch LJ, Mirro EA, Salanova V, Witt TC, Drees CN, Brown MG, Lee RW, Sadler TL, Felton EA, Rutecki P, Shin HW, Hadar E, Hegde M, Rao VR, Mnatsakanyan L, Madhavan DS, Zakaria TJ, Liu AA, Heck CN, Greenwood JE, Bigelow JK, Nair DR, Alexopoulos AV, Mackow M, Edwards JC, Sotudeh N, Kuzniecky RI, Gwinn RP, Doherty MJ, Geller EB, Morrell MJ. PMID: 32072621; PMCID: PMC7154711.
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26 Fields:
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Humans
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Dual responsive neurostimulation implants for epilepsy. J Neurosurg. 2020 01 01; 132(1):225-231.
Barbaro MF, Chesney K, Kramer DR, Kellis S, Peng T, Blumenfeld Z, Gogia AS, Lee MB, Greenwood J, Nune G, Kalayjian LA, Heck CN, Liu CY, Lee B. PMID: 30684944.
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1 Fields:
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Engineering Artificial Somatosensation Through Cortical Stimulation in Humans. Front Syst Neurosci. 2018; 12:24.
Lee B, Kramer D, Armenta Salas M, Kellis S, Brown D, Dobreva T, Klaes C, Heck C, Liu C, Andersen RA. PMID: 29915532; PMCID: PMC5994581.
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24
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Epilepsy surgery in the underserved Hispanic population improves depression, anxiety, and quality of life. Epilepsy Behav. 2018 06; 83:1-6.
Smith JAD, Armacost M, Ensign E, Shaw S, Jimenez N, Millett D, Liu C, Heck CN. PMID: 29631155.
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Radiosurgery versus open surgery for mesial temporal lobe epilepsy: The randomized, controlled ROSE trial. Epilepsia. 2018 06; 59(6):1198-1207.
Barbaro NM, Quigg M, Ward MM, Chang EF, Broshek DK, Langfitt JT, Yan G, Laxer KD, Cole AJ, Sneed PK, Hess CP, Yu W, Tripathi M, Heck CN, Miller JW, Garcia PA, McEvoy A, Fountain NB, Salanova V, Knowlton RC, Bagic A, Henry T, Kapoor S, McKhann G, Palade AE, Reuber M, Tecoma E. PMID: 29600809.
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28 Fields:
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Humans
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Preventable complications in epilepsy admissions: The "July effect". Epilepsy Res. 2017 11; 137:101-106.
Pierson NS, Kramer DR, Wen T, Ho L, Patel A, Donoho D, Mehta V, Heck C, Lee B, Mack WJ, Liu CY. PMID: 28985613.
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2 Fields:
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Humans
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The Weekend Effect on Morbidity and Mortality Among Pediatric Epilepsy Admissions. Pediatr Neurol. 2017 Sep; 74:24-31.e1.
Wen T, Kramer DR, Sirot S, Ho L, Moalem AS, Cen SY, Millett D, Heck C, Robison RA, Mack WJ, Liu CY. PMID: 28676248.
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1 Fields:
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Humans
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Potentially preventable complications in epilepsy admissions: The "weekend effect". Epilepsy Behav. 2017 05; 70(Pt A):50-56.
Ho L, Kramer DR, Wen T, Moalem AS, Millett D, Heck CN, Mack WJ, Liu CY. PMID: 28410465.
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Brain-responsive neurostimulation in patients with medically intractable mesial temporal lobe epilepsy. Epilepsia. 2017 06; 58(6):994-1004.
Geller EB, Skarpaas TL, Gross RE, Goodman RR, Barkley GL, Bazil CW, Berg MJ, Bergey GK, Cash SS, Cole AJ, Duckrow RB, Edwards JC, Eisenschenk S, Fessler J, Fountain NB, Goldman AM, Gwinn RP, Heck C, Herekar A, Hirsch LJ, Jobst BC, King-Stephens D, Labar DR, Leiphart JW, Marsh WR, Meador KJ, Mizrahi EM, Murro AM, Nair DR, Noe KH, Park YD, Rutecki PA, Salanova V, Sheth RD, Shields DC, Skidmore C, Smith MC, Spencer DC, Srinivasan S, Tatum W, Van Ness PC, Vossler DG, Wharen RE, Worrell GA, Yoshor D, Zimmerman RS, Cicora K, Sun FT, Morrell MJ. PMID: 28398014.
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109 Fields:
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Humans
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Brain-responsive neurostimulation in patients with medically intractable seizures arising from eloquent and other neocortical areas. Epilepsia. 2017 06; 58(6):1005-1014.
Jobst BC, Kapur R, Barkley GL, Bazil CW, Berg MJ, Bergey GK, Boggs JG, Cash SS, Cole AJ, Duchowny MS, Duckrow RB, Edwards JC, Eisenschenk S, Fessler AJ, Fountain NB, Geller EB, Goldman AM, Goodman RR, Gross RE, Gwinn RP, Heck C, Herekar AA, Hirsch LJ, King-Stephens D, Labar DR, Marsh WR, Meador KJ, Miller I, Mizrahi EM, Murro AM, Nair DR, Noe KH, Olejniczak PW, Park YD, Rutecki P, Salanova V, Sheth RD, Skidmore C, Smith MC, Spencer DC, Srinivasan S, Tatum W, Van Ness P, Vossler DG, Wharen RE, Worrell GA, Yoshor D, Zimmerman RS, Skarpaas TL, Morrell MJ. PMID: 28387951.
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69 Fields:
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Humans
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Dysregulation of PINCH signaling in mesial temporal epilepsy. J Clin Neurosci. 2017 Feb; 36:43-52.
Liu C, Russin J, Heck C, Kawata K, Adiga R, Yen W, Lambert J, Stear B, Law M, Marquez Y, Crino P, Millett D, Langford D. PMID: 27838154; PMCID: PMC6492941.
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7 Fields:
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HumansCells
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A sparse Laguerre-Volterra autoregressive model for seizure prediction in temporal lobe epilepsy. Annu Int Conf IEEE Eng Med Biol Soc. 2016 Aug; 2016:1664-1667.
Naiini SA, Heck CN, Liu CY, Berger TW. PMID: 28324947.
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2 Fields:
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Humans
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Hand Shape Representations in the Human Posterior Parietal Cortex. J Neurosci. 2015 Nov 18; 35(46):15466-76.
Klaes C, Kellis S, Aflalo T, Lee B, Pejsa K, Shanfield K, Hayes-Jackson S, Aisen M, Heck C, Liu C, Andersen RA. PMID: 26586832; PMCID: PMC4649012.
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26 Fields:
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HumansCells
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Neuromodulation in the Treatment of Epilepsy. Curr Treat Options Neurol. 2015 Oct; 17(10):375.
Nune G, DeGiorgio C, Heck C. PMID: 26307329.
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19
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Neurophysiology. Decoding motor imagery from the posterior parietal cortex of a tetraplegic human. Science. 2015 May 22; 348(6237):906-10.
Aflalo T, Kellis S, Klaes C, Lee B, Shi Y, Pejsa K, Shanfield K, Hayes-Jackson S, Aisen M, Heck C, Liu C, Andersen RA. PMID: 25999506; PMCID: PMC4896830.
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192 Fields:
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HumansCells
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Lateralization of mesial temporal lobe epilepsy with chronic ambulatory electrocorticography. Epilepsia. 2015 Jun; 56(6):959-67.
King-Stephens D, Mirro E, Weber PB, Laxer KD, Van Ness PC, Salanova V, Spencer DC, Heck CN, Goldman A, Jobst B, Shields DC, Bergey GK, Eisenschenk S, Worrell GA, Rossi MA, Gross RE, Cole AJ, Sperling MR, Nair DR, Gwinn RP, Park YD, Rutecki PA, Fountain NB, Wharen RE, Hirsch LJ, Miller IO, Barkley GL, Edwards JC, Geller EB, Berg MJ, Sadler TL, Sun FT, Morrell MJ. PMID: 25988840; PMCID: PMC4676303.
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62 Fields:
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Humans
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A Single-Center Experience with the NeuroPace RNS System: A Review of Techniques and Potential Problems. World Neurosurg. 2015 Sep; 84(3):719-26.
Lee B, Zubair MN, Marquez YD, Lee DM, Kalayjian LA, Heck CN, Liu CY. PMID: 25940211.
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19 Fields:
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Humans
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Long-term treatment with responsive brain stimulation in adults with refractory partial seizures. Neurology. 2015 Feb 24; 84(8):810-7.
Bergey GK, Morrell MJ, Mizrahi EM, Goldman A, King-Stephens D, Nair D, Srinivasan S, Jobst B, Gross RE, Shields DC, Barkley G, Salanova V, Olejniczak P, Cole A, Cash SS, Noe K, Wharen R, Worrell G, Murro AM, Edwards J, Duchowny M, Spencer D, Smith M, Geller E, Gwinn R, Skidmore C, Eisenschenk S, Berg M, Heck C, Van Ness P, Fountain N, Rutecki P, Massey A, O'Donovan C, Labar D, Duckrow RB, Hirsch LJ, Courtney T, Sun FT, Seale CG. PMID: 25616485; PMCID: PMC4339127.
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191 Fields:
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Humans
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A prospective long-term study of external trigeminal nerve stimulation for drug-resistant epilepsy. Epilepsy Behav. 2015 Jan; 42:44-7.
Soss J, Heck C, Murray D, Markovic D, Oviedo S, Corrale-Leyva G, Gordon S, Kealey C, DeGiorgio C. PMID: 25499162.
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18 Fields:
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HumansCTClinical Trials
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An in vitro seizure model from human hippocampal slices using multi-electrode arrays. J Neurosci Methods. 2015 Apr 15; 244:154-63.
Hsiao MC, Yu PN, Song D, Liu CY, Heck CN, Millett D, Berger TW. PMID: 25244953.
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11 Fields:
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Two-year seizure reduction in adults with medically intractable partial onset epilepsy treated with responsive neurostimulation: final results of the RNS System Pivotal trial. Epilepsia. 2014 Mar; 55(3):432-41.
Heck CN, King-Stephens D, Massey AD, Nair DR, Jobst BC, Barkley GL, Salanova V, Cole AJ, Smith MC, Gwinn RP, Skidmore C, Van Ness PC, Bergey GK, Park YD, Miller I, Geller E, Rutecki PA, Zimmerman R, Spencer DC, Goldman A, Edwards JC, Leiphart JW, Wharen RE, Fessler J, Fountain NB, Worrell GA, Gross RE, Eisenschenk S, Duckrow RB, Hirsch LJ, Bazil C, O'Donovan CA, Sun FT, Courtney TA, Seale CG, Morrell MJ. PMID: 24621228; PMCID: PMC4233950.
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187 Fields:
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Unstable periodic orbits in human epileptic hippocampal slices. Annu Int Conf IEEE Eng Med Biol Soc. 2014; 2014:5800-3.
Liu CY, Heck CN, Millett D, Berger TW. PMID: 25571314.
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1 Fields:
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A testbed to explore the optimal electrical stimulation parameters for suppressing inter-ictal spikes in human hippocampal slices. Annu Int Conf IEEE Eng Med Biol Soc. 2014; 2014:5792-5.
Liu CY, Heck CN, Millett D, Berger TW. PMID: 25571312.
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Visual field defects after radiosurgery for mesial temporal lobe epilepsy. Epilepsia. 2013 Aug; 54(8):1376-80.
Hensley-Judge H, Quigg M, Barbaro NM, Newman SA, Ward MM, Chang EF, Broshek DK, Lamborn KR, Laxer KD, Garcia P, Heck CN, Kondziolka D, Beach R, Salanova V, Goodman R. PMID: 23663063; PMCID: PMC6036909.
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6 Fields:
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Randomized controlled trial of trigeminal nerve stimulation for drug-resistant epilepsy. Neurology. 2013 Feb 26; 80(9):786-91.
DeGiorgio CM, Soss J, Cook IA, Markovic D, Gornbein J, Murray D, Oviedo S, Gordon S, Corralle-Leyva G, Kealey CP, Heck CN. PMID: 23365066; PMCID: PMC3598453.
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50 Fields:
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HumansCTClinical Trials
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Role of the hippocampus in memory formation: restorative encoding memory integration neural device as a cognitive neural prosthesis. IEEE Pulse. 2012 Sep-Oct; 3(5):17-22.
Berger T, Song D, Chan R, Shin D, Marmarelis V, Hampson R, Sweatt A, Heck C, Liu C, Wills J, Lacoss J, Granacki J, Gerhardt G, Deadwyler S. PMID: 23014702.
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4 Fields:
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HumansAnimals
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Progesterone vs placebo therapy for women with epilepsy: A randomized clinical trial. Neurology. 2012 Jun 12; 78(24):1959-66.
Herzog AG, Fowler KM, Smithson SD, Kalayjian LA, Heck CN, Sperling MR, Liporace JD, Harden CL, Dworetzky BA, Pennell PB, Massaro JM, Progesterone Trial Study Group. PMID: 22649214; PMCID: PMC3369508.
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47 Fields:
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HumansCTClinical Trials
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Spatio-temporal inter-ictal activity recorded from human epileptic hippocampal slices. Annu Int Conf IEEE Eng Med Biol Soc. 2012; 2012:5166-9.
Hsiao MC, Yu PN, Song D, Liu CY, Heck CN, Millett D, Berger TW. PMID: 23367092.
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Variation of seizure frequency with ovulatory status of menstrual cycles. Epilepsia. 2011 Oct; 52(10):1843-8.
Herzog AG, Fowler KM, Sperling MR, Liporace JD, Kalayjian LA, Heck CN, Krauss GL, Dworetzky BA, Pennell PB, Progesterone Trial Study Group. PMID: 21756250; PMCID: PMC4572701.
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15 Fields:
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Premenstrual dysphoric disorder in women with epilepsy: relationships to potential epileptic, antiepileptic drug, and reproductive endocrine factors. Epilepsy Behav. 2011 Aug; 21(4):391-6.
Herzog AG, Smithson SD, Fowler KM, Krishnamurthy KB, Sundstrom D, Kalayjian LA, Heck CN, Oviedo S, Correl-Leyva G, Garcia E, Gleason KA, Dworetzky BA. PMID: 21724471.
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1 Fields:
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Humans
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In vivo labeling and in vitro characterisation of central complex neurons involved in the control of sound production. J Neurosci Methods. 2009 Oct 15; 183(2):202-12.
Heck C, Kunst M, Härtel K, Hülsmann S, Heinrich R. PMID: 19583981.
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5 Fields:
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AnimalsCells
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Vagus nerve stimulation for epilepsy: is output current correlated with acute response? Acta Neurol Scand. 2007 Oct; 116(4):217-20.
Bunch S, DeGiorgio CM, Krahl S, Britton J, Green P, Lancman M, Murphy J, Olejniczak P, Shih J, Heck CN. PMID: 17824897.
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9 Fields:
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Vagus nerve stimulation for epilepsy: randomized comparison of three stimulation paradigms. Neurology. 2005 Jul 26; 65(2):317-9.
DeGiorgio C, Heck C, Bunch S, Britton J, Green P, Lancman M, Murphy J, Olejniczak P, Shih J, Arrambide S, Soss J. PMID: 16043810.
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29 Fields:
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Vagus nerve stimulation therapy, epilepsy, and device parameters: scientific basis and recommendations for use. Neurology. 2002 Sep 24; 59(6 Suppl 4):S31-7.
Heck C, Helmers SL, DeGiorgio CM. PMID: 12270966.
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40 Fields:
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Vagus nerve stimulation: analysis of device parameters in 154 patients during the long-term XE5 study. Epilepsia. 2001 Aug; 42(8):1017-20.
DeGiorgio CM, Thompson J, Lewis P, Arrambide S, Naritoku D, Handforth A, Labar D, Mullin P, Heck C, VNS U.S. Study Group. PMID: 11554887.
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22 Fields:
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HumansCTClinical Trials
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Prospective long-term study of vagus nerve stimulation for the treatment of refractory seizures. Epilepsia. 2000 Sep; 41(9):1195-200.
DeGiorgio CM, Schachter SC, Handforth A, Salinsky M, Thompson J, Uthman B, Reed R, Collins S, Tecoma E, Morris GL, Vaughn B, Naritoku DK, Henry T, Labar D, Gilmartin R, Labiner D, Osorio I, Ristanovic R, Jones J, Murphy J, Ney G, Wheless J, Lewis P, Heck C. PMID: 10999559.
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112 Fields:
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HumansCTClinical Trials
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Experience with vagus nerve stimulation for intractable epilepsy: some questions and answers. Neurol Med Chir (Tokyo). 1999 Jul; 39(7):489-95.
Amar AP, Heck CN, DeGiorgio CM, Apuzzo ML. PMID: 10437376.
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HumansCTClinical Trials
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Serum neuron-specific enolase in the major subtypes of status epilepticus. Neurology. 1999 Mar 10; 52(4):746-9.
DeGiorgio CM, Heck CN, Rabinowicz AL, Gott PS, Smith T, Correale J. PMID: 10078721.
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42 Fields:
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Humans
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An institutional experience with cervical vagus nerve trunk stimulation for medically refractory epilepsy: rationale, technique, and outcome. Neurosurgery. 1998 Dec; 43(6):1265-76; discussion 1276-80.
Amar AP, Heck CN, Levy ML, Smith T, DeGiorgio CM, Oviedo S, Apuzzo ML. PMID: 9848840.
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PubMed Mentions:
28 Fields:
Translation:
HumansAnimalsCTClinical Trials
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Localization of ectopic corticotropin-producing carcinoid tumor with use of indium-111 pentetreotide scintigraphy. Endocr Pract. 1998 Nov-Dec; 4(6):378-81.
Bakalakos EA, Cawley K, O'Dorisio TM, Heck C, Schirmer WJ. PMID: 15251712.
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PubMed Mentions:
1 Fields:
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Status epilepticus increases CSF levels of neuron-specific enolase and alters the blood-brain barrier. Neurology. 1998 May; 50(5):1388-91.
Correale J, Rabinowicz AL, Heck CN, Smith TD, Loskota WJ, DeGiorgio CM. PMID: 9595992.
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PubMed Mentions:
20 Fields:
Translation:
Humans
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Vagus nerve stimulation activates central nervous system structures in epileptic patients during PET H2(15)O blood flow imaging. Neurosurgery. 1996 Aug; 39(2):426-30; discussion 430-1.
Ko D, Heck C, Grafton S, Apuzzo ML, Couldwell WT, Chen T, Day JD, Zelman V, Smith T, DeGiorgio CM. PMID: 8832691.
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PubMed Mentions:
24 Fields:
Translation:
Humans
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Neuron-specific enolase, a marker of acute neuronal injury, is increased in complex partial status epilepticus. Epilepsia. 1996 Jul; 37(7):606-9.
DeGiorgio CM, Gott PS, Rabinowicz AL, Heck CN, Smith TD, Correale JD. PMID: 8681891.
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PubMed Mentions:
23 Fields:
Translation:
Humans
This graph shows the total number of publications by year. To see the data as text,
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This graph shows the total number of publications by year. To return to the graph,
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Year | Publications |
---|
1996 | 2 |
1998 | 3 |
1999 | 2 |
2000 | 1 |
2001 | 1 |
2002 | 1 |
2005 | 1 |
2007 | 1 |
2009 | 1 |
2011 | 2 |
2012 | 3 |
2013 | 2 |
2014 | 5 |
2015 | 6 |
2016 | 2 |
2017 | 5 |
2018 | 3 |
2019 | 1 |
2020 | 3 |
2021 | 2 |
2022 | 5 |
2023 | 1 |
2024 | 4 |
This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text,
click here.
This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text,
click here.
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