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Patrick Hsieh, MD

TitleProfessor of Clinical Neurological Surgery
InstitutionUniversity of Southern California
DepartmentNeurological Surgery
AddressDEI 5501
Off Campus
Los Angeles CA 90089-9314
Phone+1 323 226 7421
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    Other Positions
    TitleQuality Director, USC Spine Center


    Collapse Biography 
    Collapse Awards and Honors
    Pasadena Magazine2011Top Doctor
    2007Congress of Neurological Surgeons Depuy Spine Fellowship Award

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    Dr. Hsieh was a distinguished scholar at the Howard Hughes Medical Institute in 1998 where he performed research in the field of neuro-genetics at the National Institutes of Health. He completed a surgical internship and neurosurgery residency at Northwestern University McGaw Medical Center where he also received specialized training in spinal deformity surgery and advanced minimally invasive spine surgery. Additionally, Dr. Hsieh has specialized training in spinal oncology and complex spinal reconstructive surgery at Johns Hopkins University. Dr. Hsieh’s research interests include prospective outcome studies on spinal oncology surgery, spinal deformity surgery and minimally invasive spine procedures. He is particularly interested in clinical trials on the management of Chordomas and other primary spinal tumors. Dr. Hsieh also studies spinal biomechanics and the application of osteobiologics and nanoparticles for spine reconstructions. Additionally, his expertise and interests includes chordoma and sacral tumors and scoliosis. Dr. Hsieh has participated in five major research studies throughout his training, as well as over a dozen major presentations at national conferences. He has also co-authored over 15 peer-reviewed journal articles in scientific publications.


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Barkoh K, Lucas JW, Lee L, Hsieh P, Wang JC, Rolfe K. Paraplegic patients: how to measure balance and what is normal or functional? Eur Spine J. 2018 02; 27(Suppl 1):109-114. PMID: 29423886.
      View in: PubMed
    2. Tamai K, Buser Z, Paholpak P, Sessumpun K, Hsieh P, Nakamura H, Wang JC. MRI kinematic analysis of T1 sagittal motion between cervical flexion and extension positions in 145 patients. Eur Spine J. 2018 May; 27(5):1034-1041. PMID: 29128915.
      View in: PubMed
    3. Tamai K, Buser Z, Wang C, Paholpak P, Nakamura H, Wang JC, Hsieh P. The primary diagnosis and the coexisting anxiety disorders have no impact on the additional surgical procedure after spinal cord stimulators implantation: An analysis of 11,029 patients. J Clin Neurosci. 2018 Jan; 47:208-213. PMID: 29037934.
      View in: PubMed
    4. Pham MH, Tuchman A, Chen TC, Acosta FL, Hsieh P, Liu JC. Transpedicular Corpectomy and Cage Placement in the Treatment of Traumatic Lumbar Burst Fractures. Clin Spine Surg. 2017 Oct; 30(8):360-366. PMID: 28937458.
      View in: PubMed
    5. Layer RT, Ulich TR, Coric D, Arnold PM, Guest JD, Heary RH, Hsieh P, Jenkins AL, Kim KD, Lee KS, Masuoka LK, Neff KM, Ray WZ, Theodore N, Fehlings MG. New Clinical-Pathological Classification of Intraspinal Injury Following Traumatic Acute Complete Thoracic Spinal Cord Injury: Postdurotomy/Myelotomy Observations From the INSPIRE Trial. Neurosurgery. 2017 Sep 01; 64(CN_suppl_1):105-109. PMID: 28899037.
      View in: PubMed
    6. Acosta FL, Mehta VA, Arakelyan A, Drazin D, Cortland C, Hsieh P, Liu JC, Pham MH. A Novel Lumbar Motion Segment Classification to Predict Changes in Segmental Sagittal Alignment After Lateral Interbody Fixation. Global Spine J. 2017 Oct; 7(7):642-647. PMID: 28989843.
      View in: PubMed
    7. Dedeogullari E, Paholpak P, Barkoh K, Lucas J, Lee L, Wang C, Hsieh P, Wang JC, Buser Z. Effect of mental health on post-operative infection rates following cervical spine fusion procedures. J Orthop. 2017 Dec; 14(4):501-506. PMID: 28855766.
      View in: PubMed
    8. Jakoi AM, Pannu G, D'Oro A, Buser Z, Pham MH, Patel NN, Hsieh P, Liu JC, Acosta FL, Hah R, Wang JC. The Clinical Correlations between Diabetes, Cigarette Smoking and Obesity on Intervertebral Degenerative Disc Disease of the Lumbar Spine. Asian Spine J. 2017 Jun; 11(3):337-347. PMID: 28670401.
      View in: PubMed
    9. Stone MA, Jakoi AM, Iorio JA, Pham MH, Patel NN, Hsieh P, Liu JC, Acosta FL, Hah R, Wang JC. Bisphosphonate's and Intermittent Parathyroid Hormone's Effect on Human Spinal Fusion: A Systematic Review of the Literature. Asian Spine J. 2017 Jun; 11(3):484-493. PMID: 28670418.
      View in: PubMed
    10. Paholpak P, Nazareth A, Hsieh P, Buser Z, Wang JC. Kinematic evaluation of cervical sagittal balance and thoracic inlet alignment in degenerative cervical spondylolisthesis using kinematic magnetic resonance imaging. Spine J. 2017 09; 17(9):1272-1284. PMID: 28456677.
      View in: PubMed
    11. Heindel P, Tuchman A, Hsieh P, Pham MH, D'Oro A, Patel NN, Jakoi AM, Hah R, Liu JC, Buser Z, Wang JC. Reoperation Rates After Single-level Lumbar Discectomy. Spine (Phila Pa 1976). 2017 Apr 15; 42(8):E496-E501. PMID: 27548580.
      View in: PubMed
    12. Bakhsheshian J, Strickland BA, Patel NN, Jakoi AM, Minneti M, Zada G, Acosta FL, Hsieh P, Wang JC, Liu JC, Pham MH. The use of a novel perfusion-based cadaveric simulation model with cerebrospinal fluid reconstitution comparing dural repair techniques: a pilot study. Spine J. 2017 09; 17(9):1335-1341. PMID: 28412565.
      View in: PubMed
    13. Sayari AJ, Tuchman A, Cohen JR, Hsieh P, Buser Z, Wang JC. Risk and Cost of Reoperation After Single-Level Posterior Cervical Foraminotomy: A Large Database Study. Global Spine J. 2017 Apr; 7(2):116-122. PMID: 28507880.
      View in: PubMed
    14. Pham MH, Ohiorhenuan IE, Patel NN, Jakoi AM, Hsieh P, Acosta FL, Wang JC, Liu JC. A Portable Shoulder-Mounted Camera System for Surgical Education in Spine Surgery. Surg Technol Int. 2017 Feb 07; 30:462-467. PMID: 28182824.
      View in: PubMed
    15. Schoell K, Buser Z, Jakoi A, Pham M, Patel NN, Hsieh P, Liu JC, Wang JC. A response to a commentary by Dr. Daniel J. Cher. Spine J. 2017 01; 17(1):159. PMID: 27986244.
      View in: PubMed
    16. Chang KE, Pham MH, Hsieh P. Adjacent segment disease requiring reoperation in cervical total disc arthroplasty: A literature review and update. J Clin Neurosci. 2017 Mar; 37:20-24. PMID: 27865820.
      View in: PubMed
    17. Pham MH, Tuchman A, Chen TC, Acosta FL, Hsieh P, Liu JC. Transpedicular Corpectomy and Cage Placement in the Treatment of Traumatic Lumbar Burst Fractures. Clin Spine Surg. 2016 Jul 14. PMID: 26301730.
      View in: PubMed
    18. Pham MH, Jakoi AM, Hsieh P. S-1 and S-2-alar-iliac screw fixation via intraoperative navigation. Neurosurg Focus. 2016 Jul; 41 Video Suppl 1:1. PMID: 27364427.
      View in: PubMed
    19. Pham MH, Jakoi AM, Hsieh P. Minimally invasive L5-S1 oblique lumbar interbody fusion with anterior plate. Neurosurg Focus. 2016 Jul; 41 Video Suppl 1:1. PMID: 27364428.
      View in: PubMed
    20. Hsieh P, Mummaneni PV. Introduction to Lumbosacral and Sacropelvic Fixation Strategies. Neurosurg Focus. 2016 Jul; 41 Video Suppl 1:1. PMID: 27364425.
      View in: PubMed
    21. Schoell K, Buser Z, Jakoi A, Pham M, Patel NN, Hsieh P, Liu JC, Wang JC. Postoperative complications in patients undergoing minimally invasive sacroiliac fusion. Spine J. 2016 11; 16(11):1324-1332. PMID: 27349627.
      View in: PubMed
    22. Fehlings MG, Tetreault L, Hsieh P, Traynelis V, Wang MY. Introduction: Degenerative cervical myelopathy: diagnostic, assessment, and management strategies, surgical complications, and outcome prediction. Neurosurg Focus. 2016 Jun; 40(6):E1. PMID: 27246479.
      View in: PubMed
    23. Weng C, Wang J, Tuchman A, Wang J, Fu C, Hsieh P, Buser Z, Wang JC. Influence of T1 Slope on the Cervical Sagittal Balance in Degenerative Cervical Spine: An Analysis Using Kinematic MRI. Spine (Phila Pa 1976). 2016 Feb; 41(3):185-90. PMID: 26650871.
      View in: PubMed
    24. Pham MH, Mehta VA, Patel NN, Jakoi AM, Hsieh P, Liu JC, Wang JC, Acosta FL. Complications associated with the Dynesys dynamic stabilization system: a comprehensive review of the literature. Neurosurg Focus. 2016 Jan; 40(1):E2. PMID: 26721576.
      View in: PubMed
    25. Wu JC, Hsieh P, Mummaneni PV, Wang MY. Spinal Motion Preservation Surgery. Biomed Res Int. 2015; 2015:372502. PMID: 26881197; PMCID: PMC4736217.
    26. D'Oro A, Spoonamore MJ, Cohen JR, Acosta FL, Hsieh P, Liu JC, Chen TC, Buser Z, Wang JC. Effects of fusion and conservative treatment on disc degeneration and rates of subsequent surgery after thoracolumbar fracture. J Neurosurg Spine. 2016 Mar; 24(3):476-82. PMID: 26637065.
      View in: PubMed
    27. Pham MH, Mehta VA, Tuchman A, Hsieh P. Material Science in Cervical Total Disc Replacement. Biomed Res Int. 2015; 2015:719123. PMID: 26523281; PMCID: PMC4615218.
    28. Pham MH, Tuchman A, Platt A, Hsieh P. Intracranial complications associated with spinal surgery. Eur Spine J. 2016 Mar; 25(3):888-94. PMID: 26377547.
      View in: PubMed
    29. Smith JA, Tuchman A, Huoh M, Kaiser AM, Schooler WG, Hsieh P. Locomotor biomechanics after total sacrectomy: a case report. Spine (Phila Pa 1976). 2014 Nov 15; 39(24):E1481-7. PMID: 25202931.
      View in: PubMed
    30. Tuchman A, Pham M, Hsieh P. The indications and timing for operative management of spinal epidural abscess: literature review and treatment algorithm. Neurosurg Focus. 2014 Aug; 37(2):E8. PMID: 25081968.
      View in: PubMed
    31. Hsieh P, Liu JC, Wang MY. Introduction: vertebral osteomyelitis and spinal epidural abscess. Neurosurg Focus. 2014 Aug; 37(2):1 p preceding E1. PMID: 25081970.
      View in: PubMed
    32. Molina CA, Ames CP, Chou D, Rhines LD, Hsieh P, Zadnik PL, Wolinsky JP, Gokaslan ZL, Sciubba DM. Outcomes following attempted en bloc resection of cervical chordomas in the C-1 and C-2 region versus the subaxial region: a multiinstitutional experience. J Neurosurg Spine. 2014 Sep; 21(3):348-56. PMID: 24926926.
      View in: PubMed
    33. Acosta FL, Ames C, Hsieh P, McCarthy IM. Introduction: Costs and benefits of modern-day spine care. Neurosurg Focus. 2014 Jun; 36(6):Introduction. PMID: 24881639.
      View in: PubMed
    34. Tuchman A, Hsieh P. Editorial: Comparing minimally invasive, hybrid, and open surgical techniques for adult spinal deformity. Neurosurg Focus. 2014 May; 36(5):E16. PMID: 24785481.
      View in: PubMed
    35. Tsai MT, Wu HY, Roan JN, Tsai YS, Hsieh P, Yang YJ, Luo CY. Effect of false lumen partial thrombosis on repaired acute type A aortic dissection. J Thorac Cardiovasc Surg. 2014 Nov; 148(5):2140-2146.e3. PMID: 24656670.
      View in: PubMed
    36. Gonzalez AA, Shilian P, Hsieh P. Spinal cord mapping. J Clin Neurophysiol. 2013 Dec; 30(6):604-12. PMID: 24300985.
      View in: PubMed
    37. Russin JJ, Attenello FJ, Amar AP, Liu CY, Apuzzo ML, Hsieh P. Computed tomography for clearance of cervical spine injury in the unevaluable patient. World Neurosurg. 2013 Sep-Oct; 80(3-4):405-13. PMID: 23321374.
      View in: PubMed
    38. Hsieh P. Considering the cost of spine surgeries: is it necessary? World Neurosurg. 2013 Jul-Aug; 80(1-2):71-3. PMID: 23111216.
      View in: PubMed
    39. Clarke MJ, Dasenbrock H, Bydon A, Sciubba DM, McGirt MJ, Hsieh P, Yassari R, Gokaslan ZL, Wolinsky JP. Posterior-only approach for en bloc sacrectomy: clinical outcomes in 36 consecutive patients. Neurosurgery. 2012 Aug; 71(2):357-64; discussion 364. PMID: 22569060.
      View in: PubMed
    40. Lee B, Hsieh P. Minimally invasive lumbar intradural extramedullary tumor resection. Neurosurg Focus. 2012 Jul; 33(Suppl 1):1. PMID: 26016399.
      View in: PubMed
    41. Hsieh P. Efficacy of surgical treatment for lumbar stenosis with the X-STOP: an issue in need of closer inspection. World Neurosurg. 2013 Jul-Aug; 80(1-2):74-7. PMID: 22634461.
      View in: PubMed
    42. Taghva A, Attenello FJ, Zada G, Khalessi AA, Hsieh P. Minimally invasive posterior atlantoaxial fusion: a cadaveric and clinical feasibility study. World Neurosurg. 2013 Sep-Oct; 80(3-4):414-21. PMID: 22381857.
      View in: PubMed
    43. Hsieh P, Gallia GL, Sciubba DM, Bydon A, Marco RA, Rhines L, Wolinsky JP, Gokaslan ZL. En bloc excisions of chordomas in the cervical spine: review of five consecutive cases with more than 4-year follow-up. Spine (Phila Pa 1976). 2011 Nov 15; 36(24):E1581-7. PMID: 22048652.
      View in: PubMed
    44. Hsieh P, Gokaslan ZL. Complications of spine surgery. Neurosurg Focus. 2011 Oct; 31(4):1 p preceding E1. PMID: 21961873.
      View in: PubMed
    45. Terterov S, Taghva A, Khalessi AA, Hsieh P. Symptomatic vertebral artery compression by the rod of a C1-C2 posterior fusion construct: case report and review of the literature. Spine (Phila Pa 1976). 2011 May 01; 36(10):E678-81. PMID: 21270689.
      View in: PubMed
    46. Hsieh P. Thoracic discectomy and plating. Neurosurg Focus. 2011 Apr; 30(4):E16. PMID: 21456927.
      View in: PubMed
    47. Hsieh P, Wang MY. Introduction. Ossification of the posterior longitudinal ligament. Neurosurg Focus. 2011 Mar; 30(3):1 p preceding E1. PMID: 21434825.
      View in: PubMed
    48. Jones J, Lerner A, Kim PE, Law M, Hsieh P. Diffusion tensor imaging in the assessment of ossification of the posterior longitudinal ligament: a report on preliminary results in 3 cases and review of the literature. Neurosurg Focus. 2011 Mar; 30(3):E14. PMID: 21361752.
      View in: PubMed
    49. Pham MH, Attenello FJ, Lucas J, He S, Stapleton CJ, Hsieh P. Conservative management of ossification of the posterior longitudinal ligament. A review. Neurosurg Focus. 2011 Mar; 30(3):E2. PMID: 21434818.
      View in: PubMed
    50. Stapleton CJ, Pham MH, Attenello FJ, Hsieh P. Ossification of the posterior longitudinal ligament: genetics and pathophysiology. Neurosurg Focus. 2011 Mar; 30(3):E6. PMID: 21434822.
      View in: PubMed
    51. Hsieh P, Stapleton CJ, Moldavskiy P, Koski TR, Ondra SL, Gokaslan ZL, Kuntz C. Posterior vertebral column subtraction osteotomy for the treatment of tethered cord syndrome: review of the literature and clinical outcomes of all cases reported to date. Neurosurg Focus. 2010 Jul; 29(1):E6. PMID: 20594004.
      View in: PubMed
    52. Taghva A, Li KW, Liu JC, Gokaslan ZL, Hsieh P. Minimally invasive circumferential spinal decompression and stabilization for symptomatic metastatic spine tumor: technical case report. Neurosurgery. 2010 Mar; 66(3):E620-2. PMID: 20173535.
      View in: PubMed
    53. O'shaughnessy BA, Kuklo TR, Hsieh P, Yang BP, Koski TR, Ondra SL. Thoracic pedicle subtraction osteotomy for fixed sagittal spinal deformity. Spine (Phila Pa 1976). 2009 Dec 15; 34(26):2893-9. PMID: 20010396.
      View in: PubMed
    54. Hsieh P, Li KW, Sciubba DM, Suk I, Wolinsky JP, Gokaslan ZL. Posterior-only approach for total en bloc spondylectomy for malignant primary spinal neoplasms: anatomic considerations and operative nuances. Neurosurgery. 2009 Dec; 65(6 Suppl):173-81; discussion 181. PMID: 19934992.
      View in: PubMed
    55. Sciubba DM, Petteys RJ, Shakur SF, Gokaslan ZL, McCarthy EF, Collins MT, McGirt MJ, Hsieh P, Nelson CS, Wolinsky JP. En bloc spondylectomy for treatment of tumor-induced osteomalacia. J Neurosurg Spine. 2009 Nov; 11(5):600-4. PMID: 19929364.
      View in: PubMed
    56. Gonzalez AA, Jeyanandarajan D, Hansen C, Zada G, Hsieh P. Intraoperative neurophysiological monitoring during spine surgery: a review. Neurosurg Focus. 2009 Oct; 27(4):E6. PMID: 19795955.
      View in: PubMed
    57. Hsieh P, Xu R, Sciubba DM, McGirt MJ, Nelson C, Witham TF, Wolinksy JP, Gokaslan ZL. Long-term clinical outcomes following en bloc resections for sacral chordomas and chondrosarcomas: a series of twenty consecutive patients. Spine (Phila Pa 1976). 2009 Sep 15; 34(20):2233-9. PMID: 19752710.
      View in: PubMed
    58. Hsieh P, Ondra SL, Grande AW, O'Shaughnessy BA, Bierbrauer K, Crone KR, Halpin RJ, Suk I, Koski TR, Gokaslan ZL, Kuntz C. Posterior vertebral column subtraction osteotomy: a novel surgical approach for the treatment of multiple recurrences of tethered cord syndrome. J Neurosurg Spine. 2009 Apr; 10(4):278-86. PMID: 19441983.
      View in: PubMed
    59. Sugrue PA, Hsieh P, Getch CC, Batjer HH. Acute symptomatic cerebellar tonsillar herniation following intraoperative lumbar drainage. J Neurosurg. 2009 Apr; 110(4):800-3. PMID: 18847338.
      View in: PubMed
    60. Hsieh P, Awad IA, Getch CC, Bendok BR, Rosenblatt SS, Batjer HH. Current updates in perioperative management of intracerebral hemorrhage. Neurosurg Clin N Am. 2008 Jul; 19(3):401-14, v. PMID: 18790376.
      View in: PubMed
    61. O'Shaughnessy BA, Liu JC, Hsieh P, Koski TR, Ganju A, Ondra SL. Surgical treatment of fixed cervical kyphosis with myelopathy. Spine (Phila Pa 1976). 2008 Apr 01; 33(7):771-8. PMID: 18379404.
      View in: PubMed
    62. Sciubba DM, Nelson C, Hsieh P, Gokaslan ZL, Ondra S, Bydon A. Perioperative challenges in the surgical management of ankylosing spondylitis. Neurosurg Focus. 2008; 24(1):E10. PMID: 18290736.
      View in: PubMed
    63. Sciubba DM, Hsieh P, McLoughlin GS, Jallo GI. Pediatric tumors involving the spinal column. Neurosurg Clin N Am. 2008 Jan; 19(1):81-92. PMID: 18156051.
      View in: PubMed
    64. Chi JH, Bydon A, Hsieh P, Witham T, Wolinsky JP, Gokaslan ZL. Epidemiology and demographics for primary vertebral tumors. Neurosurg Clin N Am. 2008 Jan; 19(1):1-4. PMID: 18156042.
      View in: PubMed
    65. Hsieh P, Koski TR, Sciubba DM, Moller DJ, O'Shaughnessy BA, Li KW, Gokaslan ZL, Ondra SL, Fessler RG, Liu JC. Maximizing the potential of minimally invasive spine surgery in complex spinal disorders. Neurosurg Focus. 2008; 25(2):E19. PMID: 18673048.
      View in: PubMed
    66. Hsieh P, Koski TR, O'Shaughnessy BA, Sugrue P, Salehi S, Ondra S, Liu JC. Anterior lumbar interbody fusion in comparison with transforaminal lumbar interbody fusion: implications for the restoration of foraminal height, local disc angle, lumbar lordosis, and sagittal balance. J Neurosurg Spine. 2007 Oct; 7(4):379-86. PMID: 17933310.
      View in: PubMed
    67. Hsieh P, Ondra SL, Wienecke RJ, O'Shaughnessy BA, Koski TR. A novel approach to sagittal balance restoration following iatrogenic sacral fracture and resulting sacral kyphotic deformity. Technical note. J Neurosurg Spine. 2007 Apr; 6(4):368-72. PMID: 17436929.
      View in: PubMed
    68. Hsieh P, Awad IA, Getch CC, Bendok BR, Rosenblatt SS, Batjer HH. Current updates in perioperative management of intracerebral hemorrhage. Neurol Clin. 2006 Nov; 24(4):745-64. PMID: 16935200.
      View in: PubMed
    69. Hsieh P, Chandler JP, Bhangoo S, Panagiotopoulos K, Kalapurakal JA, Marymont MH, Cozzens JW, Levy RM, Salehi S. Adjuvant gamma knife stereotactic radiosurgery at the time of tumor progression potentially improves survival for patients with glioblastoma multiforme. Neurosurgery. 2005 Oct; 57(4):684-92; discussion 684-92. PMID: 16239880.
      View in: PubMed
    70. Hsieh P, Wienecke RJ, O'Shaughnessy BA, Koski TR, Ondra SL. Surgical strategies for vertebral osteomyelitis and epidural abscess. Neurosurg Focus. 2004 Dec 15; 17(6):E4. PMID: 15636574.
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