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Susanne Hempel

Title(s)Professor of Research Preventive Medicine
Emailsusanneh@usc.edu
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    Collapse Biography 
    Collapse Education and Training
    University of Halle-Wittenberg, Halle, GermanyPhD2000Psychology
    University of Bielefeld, Bielefeld, GermanyMS1995Psychology
    University of Bielefeld, Bielefeld, GermanyBA1993Psychology

    Collapse Overview 
    Collapse Overview
    Susanne Hempel is a professor of research Preventative Medicine and faculty member at the Gehr Center for Health Systems Sciences and Innovation, USC Keck School of Medicine. She directs research at the Southern California Evidence Review Center (sites.usc.edu/socalevidencereview, https://www.rand.org/health-care/centers/epc.html), leading contracts for federal agencies such as the Agency for Healthcare Research and Quality (AHRQ), the Psychological Health Center of Excellence (PHCoE), and the Department of Veterans Affairs (VA), as well as nonprofit organizations such as the Patient-Centered Outcomes Research Institute (PCORI). Dr. Hempel oversees a large portfolio of evidence synthesis projects; including systematic reviews, scoping reviews, and stakeholder panels; and leads large multi-site and multi-discipline projects. Dr. Hempel is an affiliate adjunct senior behavioral scientist at RAND and a professor at the Pardee RAND Graduate School (PRGS) teaching systematic review methodology and applied psychometrics. Prior, she worked at the Center for Reviews and Dissemination (CRD), University of York, UK. Her academic background is personality psychology with a PhD from the University of Halle-Wittenberg, Germany.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Richardson AS, Chen C, Sturm R, Azhar G, Miles J, Larkin J, Motala A, Hempel S. Obesity Prevention Interventions and Implications for Energy Balance in the United States and Mexico: A Systematic Review of the Evidence and Meta-Analysis. Obesity (Silver Spring). 2019 Jul 20. PMID: 31325241.
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    2. Giannitrapani K, Holliday J, Miake-Lye I, Hempel S, Taylor SL. Synthesizing the Strength of the Evidence of Complementary and Integrative Health Therapies for Pain. Pain Med. 2019 May 09. PMID: 31070752.
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    3. Hempel S, Miake-Lye I, Brega AG, Buckhold F, Hassell S, Nowalk MP, Rubenstein L, Schreiber K, Spector WD, Kilbourne AM, Ganz DA. Quality Improvement Toolkits: Recommendations for Development. Am J Med Qual. 2019 Jan 24; 1062860618822102. PMID: 30675797.
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    4. Hilton LG, Marshall NJ, Motala A, Taylor SL, Miake-Lye IM, Baxi S, Shanman RM, Solloway MR, Beroesand JM, Hempel S. Mindfulness meditation for workplace wellness: An evidence map. Work. 2019; 63(2):205-218. PMID: 31156202.
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    5. Ahluwalia SC, Chen C, Raaen L, Motala A, Walling AM, Chamberlin M, O'Hanlon C, Larkin J, Lorenz K, Akinniranye O, Hempel S. A Systematic Review in Support of the National Consensus Project Clinical Practice Guidelines for Quality Palliative Care, Fourth Edition. J Pain Symptom Manage. 2018 Dec; 56(6):831-870. PMID: 30391049.
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    6. Tricco AC, Lillie E, Zarin W, O'Brien KK, Colquhoun H, Levac D, Moher D, Peters MDJ, Horsley T, Weeks L, Hempel S, Akl EA, Chang C, McGowan J, Stewart L, Hartling L, Aldcroft A, Wilson MG, Garritty C, Lewin S, Godfrey CM, Macdonald MT, Langlois EV, Soares-Weiser K, Moriarty J, Clifford T, Tunçalp Ö, Straus SE. PRISMA Extension for Scoping Reviews (PRISMA-ScR): Checklist and Explanation. Ann Intern Med. 2018 Oct 02; 169(7):467-473. PMID: 30178033.
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    7. Apaydin EA, Maher AR, Raaen L, Motala A, Baxi S, Shanman RM, Hempel S. The Use of Technology in the Clinical Care of Depression: An Evidence Map. J Clin Psychiatry. 2018 Aug 21; 79(5). PMID: 30152646.
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    8. Pedersen ER, Rubenstein L, Kandrack R, Danz M, Belsher B, Motala A, Booth M, Larkin J, Hempel S. Elusive search for effective provider interventions: a systematic review of provider interventions to increase adherence to evidence-based treatment for depression. Implement Sci. 2018 07 20; 13(1):99. PMID: 30029676.
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    9. Maglione MA, Raaen L, Chen C, Azhar G, Shahidinia N, Shen M, Maksabedian E, Shanman RM, Newberry S, Hempel S. Effects of medication assisted treatment (MAT) for opioid use disorder on functional outcomes: A systematic review. J Subst Abuse Treat. 2018 Jun; 89:28-51. PMID: 29706172.
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    10. Yepes-Nuñez JJ, Morgan RL, Mbuagbaw L, Carrasco-Labra A, Chang S, Hempel S, Shekelle P, Helfand M, Baldeh T, Schünemann HJ. Two alternatives versus the standard Grading of Recommendations Assessment, Development and Evaluation (GRADE) summary of findings (SoF) tables to improve understanding in the presentation of systematic review results: a three-arm, randomised, controlled, non-inferiority trial. BMJ Open. 2018 01 23; 8(1):e015623. PMID: 29362242.
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    11. MacQueen IT, Maggard-Gibbons M, Capra G, Raaen L, Ulloa JG, Shekelle PG, Miake-Lye I, Beroes JM, Hempel S. Recruiting Rural Healthcare Providers Today: a Systematic Review of Training Program Success and Determinants of Geographic Choices. J Gen Intern Med. 2018 Feb; 33(2):191-199. PMID: 29181791.
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    12. Grant S, Colaiaco B, Motala A, Shanman R, Booth M, Sorbero M, Hempel S. Mindfulness-based Relapse Prevention for Substance Use Disorders: A Systematic Review and Meta-analysis. J Addict Med. 2017 Sep/Oct; 11(5):386-396. PMID: 28727663.
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    13. Butler M, Epstein RA, Totten A, Whitlock EP, Ansari MT, Damschroder LJ, Balk E, Bass EB, Berkman ND, Hempel S, Iyer S, Schoelles K, Guise JM. AHRQ series on complex intervention systematic reviews-paper 3: adapting frameworks to develop protocols. J Clin Epidemiol. 2017 Oct; 90:19-27. PMID: 28720510.
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    14. Hilton L, Hempel S, Ewing BA, Apaydin E, Xenakis L, Newberry S, Colaiaco B, Maher AR, Shanman RM, Sorbero ME, Maglione MA. Mindfulness Meditation for Chronic Pain: Systematic Review and Meta-analysis. Ann Behav Med. 2017 Apr; 51(2):199-213. PMID: 27658913.
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    15. Grant S, Colaiaco B, Motala A, Shanman R, Sorbero M, Hempel S. Acupuncture for the Treatment of Adults with Posttraumatic Stress Disorder: A Systematic Review and Meta-Analysis. J Trauma Dissociation. 2018 Jan-Feb; 19(1):39-58. PMID: 28151093.
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    16. Hartling L, Guise JM, Hempel S, Featherstone R, Mitchell MD, Motu'apuaka ML, Robinson KA, Schoelles K, Totten A, Whitlock E, Wilt TJ, Anderson J, Berliner E, Gozu A, Kato E, Paynter R, Umscheid CA. Fit for purpose: perspectives on rapid reviews from end-user interviews. Syst Rev. 2017 02 17; 6(1):32. PMID: 28212677.
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    17. Hempel S, Graham GD, Fu N, Estrada E, Chen AY, Miake-Lye I, Miles JN, Shanman R, Shekelle PG, Beroes JM, Wallin MT. A systematic review of modifiable risk factors in the progression of multiple sclerosis. Mult Scler. 2017 Apr; 23(4):525-533. PMID: 28151053.
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    18. Hempel S, Graham GD, Fu N, Estrada E, Chen AY, Miake-Lye I, Miles JN, Shanman R, Shekelle PG, Beroes JM, Wallin MT. A systematic review of the effects of modifiable risk factor interventions on the progression of multiple sclerosis. Mult Scler. 2017 Apr; 23(4):513-524. PMID: 28151074.
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    19. Maglione MA, Maher AR, Ewing B, Colaiaco B, Newberry S, Kandrack R, Shanman RM, Sorbero ME, Hempel S. Efficacy of mindfulness meditation for smoking cessation: A systematic review and meta-analysis. Addict Behav. 2017 06; 69:27-34. PMID: 28126511.
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    20. Apaydin EA, Maher AR, Shanman R, Booth MS, Miles JN, Sorbero ME, Hempel S. A systematic review of St. John's wort for major depressive disorder. Syst Rev. 2016 09 02; 5(1):148. PMID: 27589952.
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    21. Hilton L, Maher AR, Colaiaco B, Apaydin E, Sorbero ME, Booth M, Shanman RM, Hempel S. Meditation for posttraumatic stress: Systematic review and meta-analysis. Psychol Trauma. 2017 Jul; 9(4):453-460. PMID: 27537781.
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    22. Solloway MR, Taylor SL, Shekelle PG, Miake-Lye IM, Beroes JM, Shanman RM, Hempel S. An evidence map of the effect of Tai Chi on health outcomes. Syst Rev. 2016 07 27; 5(1):126. PMID: 27460789.
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    23. Maher AR, Hempel S, Apaydin E, Shanman RM, Booth M, Miles JN, Sorbero ME. St. John's Wort for Major Depressive Disorder: A Systematic Review. Rand Health Q. 2016 May 09; 5(4):12. PMID: 28083422.
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    24. Grant S, Kandrack R, Motala A, Shanman R, Booth M, Miles J, Sorbero M, Hempel S. Acupuncture for substance use disorders: A systematic review and meta-analysis. Drug Alcohol Depend. 2016 Jun 01; 163:1-15. PMID: 26968093.
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    25. Miake-Lye IM, Hempel S, Shanman R, Shekelle PG. What is an evidence map? A systematic review of published evidence maps and their definitions, methods, and products. Syst Rev. 2016 Feb 10; 5:28. PMID: 26864942.
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    26. Hempel S, Shekelle PG, Liu JL, Sherwood Danz M, Foy R, Lim YW, Motala A, Rubenstein LV. Development of the Quality Improvement Minimum Quality Criteria Set (QI-MQCS): a tool for critical appraisal of quality improvement intervention publications. BMJ Qual Saf. 2015 Dec; 24(12):796-804. PMID: 26311020.
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    27. Hempel S, Maggard-Gibbons M, Nguyen DK, Dawes AJ, Miake-Lye I, Beroes JM, Booth MJ, Miles JN, Shanman R, Shekelle PG. Wrong-Site Surgery, Retained Surgical Items, and Surgical Fires : A Systematic Review of Surgical Never Events. JAMA Surg. 2015 Aug; 150(8):796-805. PMID: 26061125.
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    28. Lokker C, McKibbon KA, Colquhoun H, Hempel S. A scoping review of classification schemes of interventions to promote and integrate evidence into practice in healthcare. Implement Sci. 2015 Mar 03; 10:27. PMID: 25885047.
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    29. Kittel-Schneider S, Reuß M, Meyer A, Weber H, Gessner A, Leistner C, Kopf J, Schmidt B, Hempel S, Volkert J, Lesch KP, Reif A. Multi-level biomarker analysis of nitric oxide synthase isoforms in bipolar disorder and adult ADHD. J Psychopharmacol. 2015 Jan; 29(1):31-8. PMID: 25320160.
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    30. Maglione MA, Gidengil C, Das L, Raaen L, Smith A, Chari R, Newberry S, Hempel S, Shanman R, Perry T, Goetz MB. Safety of Vaccines Used for Routine Immunization in the United States. Evid Rep Technol Assess (Full Rep). 2014 Jul; (215):1-740. PMID: 30257278.
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    31. Unterecker S, Reif A, Hempel S, Proft F, Riederer P, Deckert J, Pfuhlmann B. Interaction of valproic acid and the antidepressant drugs doxepin and venlafaxine: analysis of therapeutic drug monitoring data under naturalistic conditions. Int Clin Psychopharmacol. 2014 Jul; 29(4):206-11. PMID: 24374906.
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    32. Colquhoun H, Leeman J, Michie S, Lokker C, Bragge P, Hempel S, McKibbon KA, Peters GJ, Stevens KR, Wilson MG, Grimshaw J. Towards a common terminology: a simplified framework of interventions to promote and integrate evidence into health practices, systems, and policies. Implement Sci. 2014 May 01; 9:51. PMID: 24885553.
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    33. Hempel S. Probiotics for diarrhoea. Indian J Med Res. 2014 Mar; 139(3):339-41. PMID: 24820827.
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    34. Kittel-Schneider S, Weigl J, Volkert J, Geßner A, Schmidt B, Hempel S, Kiel T, Olmes DG, Bartl J, Weber H, Kopf J, Reif A. Further evidence for plasma progranulin as a biomarker in bipolar disorder. J Affect Disord. 2014 Mar; 157:87-91. PMID: 24581833.
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    35. Ovretveit J, Hempel S, Magnabosco JL, Mittman BS, Rubenstein LV, Ganz DA. Guidance for research-practice partnerships (R-PPs) and collaborative research. J Health Organ Manag. 2014; 28(1):115-26. PMID: 24783669.
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    36. Rubenstein L, Khodyakov D, Hempel S, Danz M, Salem-Schatz S, Foy R, O'Neill S, Dalal S, Shekelle P. How can we recognize continuous quality improvement? Int J Qual Health Care. 2014 Feb; 26(1):6-15. PMID: 24311732.
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    37. Weber H, Scholz CJ, Jacob CP, Heupel J, Kittel-Schneider S, Erhardt A, Hempel S, Schmidt B, Kiel T, Gessner A, Lesch KP, Reif A. SPOCK3, a risk gene for adult ADHD and personality disorders. Eur Arch Psychiatry Clin Neurosci. 2014 Aug; 264(5):409-21. PMID: 24292267.
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    38. Hempel S, Miles JN, Booth MJ, Wang Z, Morton SC, Shekelle PG. Risk of bias: a simulation study of power to detect study-level moderator effects in meta-analysis. Syst Rev. 2013 Nov 28; 2:107. PMID: 24286208.
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    39. Ahmadzai N, Newberry SJ, Maglione MA, Tsertsvadze A, Ansari MT, Hempel S, Motala A, Tsouros S, Schneider Chafen JJ, Shanman R, Moher D, Shekelle PG. A surveillance system to assess the need for updating systematic reviews. Syst Rev. 2013 Nov 14; 2:104. PMID: 24225065.
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    40. Danz MS, Hempel S, Lim YW, Shanman R, Motala A, Stockdale S, Shekelle P, Rubenstein L. Incorporating evidence review into quality improvement: meeting the needs of innovators. BMJ Qual Saf. 2013 Nov; 22(11):931-9. PMID: 23832925.
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    41. Hempel S, Newberry S, Wang Z, Booth M, Shanman R, Johnsen B, Shier V, Saliba D, Spector WD, Ganz DA. Hospital fall prevention: a systematic review of implementation, components, adherence, and effectiveness. J Am Geriatr Soc. 2013 Apr; 61(4):483-94. PMID: 23527904.
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    42. Miake-Lye IM, Hempel S, Ganz DA, Shekelle PG. Inpatient fall prevention programs as a patient safety strategy: a systematic review. Ann Intern Med. 2013 Mar 05; 158(5 Pt 2):390-6. PMID: 23460095.
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    43. Hartling L, Hamm MP, Milne A, Vandermeer B, Santaguida PL, Ansari M, Tsertsvadze A, Hempel S, Shekelle P, Dryden DM. Testing the risk of bias tool showed low reliability between individual reviewers and across consensus assessments of reviewer pairs. J Clin Epidemiol. 2013 Sep; 66(9):973-81. PMID: 22981249.
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    44. Dalal SR, Shekelle PG, Hempel S, Newberry SJ, Motala A, Shetty KD. A pilot study using machine learning and domain knowledge to facilitate comparative effectiveness review updating. Med Decis Making. 2013 04; 33(3):343-55. PMID: 22961102.
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    45. Hempel S, Newberry SJ, Maher AR, Wang Z, Miles JN, Shanman R, Johnsen B, Shekelle PG. Probiotics for the prevention and treatment of antibiotic-associated diarrhea: a systematic review and meta-analysis. JAMA. 2012 May 09; 307(18):1959-69. PMID: 22570464.
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    46. Engelhorn T, Michelson G, Waerntges S, Hempel S, El-Rafei A, Struffert T, Doerfler A. A new approach to assess intracranial white matter abnormalities in glaucoma patients: changes of fractional anisotropy detected by 3T diffusion tensor imaging. Acad Radiol. 2012 Apr; 19(4):485-8. PMID: 22277635.
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    47. Khodyakov D, Hempel S, Rubenstein L, Shekelle P, Foy R, Salem-Schatz S, O'Neill S, Danz M, Dalal S. Conducting online expert panels: a feasibility and experimental replicability study. BMC Med Res Methodol. 2011 Dec 23; 11:174. PMID: 22196011; PMCID: PMC3313865.
    48. Hempel S, Rubenstein LV, Shanman RM, Foy R, Golder S, Danz M, Shekelle PG. Identifying quality improvement intervention publications--a comparison of electronic search strategies. Implement Sci. 2011 Aug 01; 6:85. PMID: 21806808.
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    49. O'Neill SM, Hempel S, Lim YW, Danz MS, Foy R, Suttorp MJ, Shekelle PG, Rubenstein LV. Identifying continuous quality improvement publications: what makes an improvement intervention 'CQI'? BMJ Qual Saf. 2011 Dec; 20(12):1011-9. PMID: 21727199.
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    50. Soban LM, Hempel S, Munjas BA, Miles J, Rubenstein LV. Preventing pressure ulcers in hospitals: A systematic review of nurse-focused quality improvement interventions. Jt Comm J Qual Patient Saf. 2011 Jun; 37(6):245-52. PMID: 21706984.
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    51. Taylor SL, Dy S, Foy R, Hempel S, McDonald KM, Ovretveit J, Pronovost PJ, Rubenstein LV, Wachter RM, Shekelle PG. What context features might be important determinants of the effectiveness of patient safety practice interventions? BMJ Qual Saf. 2011 Jul; 20(7):611-7. PMID: 21617166.
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    52. Dy SM, Taylor SL, Carr LH, Foy R, Pronovost PJ, Ovretveit J, Wachter RM, Rubenstein LV, Hempel S, McDonald KM, Shekelle PG. A framework for classifying patient safety practices: results from an expert consensus process. BMJ Qual Saf. 2011 Jul; 20(7):618-24. PMID: 21610267.
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    53. Shekelle PG, Pronovost PJ, Wachter RM, Taylor SL, Dy SM, Foy R, Hempel S, McDonald KM, Ovretveit J, Rubenstein LV, Adams AS, Angood PB, Bates DW, Bickman L, Carayon P, Donaldson L, Duan N, Farley DO, Greenhalgh T, Haughom J, Lake ET, Lilford R, Lohr KN, Meyer GS, Miller MR, Neuhauser DV, Ryan G, Saint S, Shojania KG, Shortell SM, Stevens DP, Walshe K. Advancing the science of patient safety. Ann Intern Med. 2011 May 17; 154(10):693-6. PMID: 21576538.
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    54. Ovretveit JC, Shekelle PG, Dy SM, McDonald KM, Hempel S, Pronovost P, Rubenstein L, Taylor SL, Foy R, Wachter RM. How does context affect interventions to improve patient safety? An assessment of evidence from studies of five patient safety practices and proposals for research. BMJ Qual Saf. 2011 Jul; 20(7):604-10. PMID: 21493589.
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    55. Hempel S, Newberry S, Ruelaz A, Wang Z, Miles JN, Suttorp MJ, Johnsen B, Shanman R, Slusser W, Fu N, Smith A, Roth B, Polak J, Motala A, Perry T, Shekelle PG. Safety of probiotics used to reduce risk and prevent or treat disease. Evid Rep Technol Assess (Full Rep). 2011 Apr; (200):1-645. PMID: 23126627; PMCID: PMC4780970.
    56. Foy R, Ovretveit J, Shekelle PG, Pronovost PJ, Taylor SL, Dy S, Hempel S, McDonald KM, Rubenstein LV, Wachter RM. The role of theory in research to develop and evaluate the implementation of patient safety practices. BMJ Qual Saf. 2011 May; 20(5):453-9. PMID: 21317181.
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    57. Shane AL, Cabana MD, Vidry S, Merenstein D, Hummelen R, Ellis CL, Heimbach JT, Hempel S, Lynch SV, Sanders ME, Tancredi DJ. Guide to designing, conducting, publishing and communicating results of clinical studies involving probiotic applications in human participants. Gut Microbes. 2010 Jul; 1(4):243-253. PMID: 21327031.
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    58. Foy R, Hempel S, Rubenstein L, Suttorp M, Seelig M, Shanman R, Shekelle PG. Meta-analysis: effect of interactive communication between collaborating primary care physicians and specialists. Ann Intern Med. 2010 Feb 16; 152(4):247-58. PMID: 20157139.
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    59. Hempel S, Norman G, Golder S, Aguiar-Ibáñez R, Eastwood A. Psychosocial interventions for non-professional carers of people with Parkinson's disease: a systematic scoping review. J Adv Nurs. 2008 Nov; 64(3):214-28. PMID: 18785883.
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    60. Chambers D, Bagnall AM, Hempel S, Forbes C. Interventions for the treatment, management and rehabilitation of patients with chronic fatigue syndrome/myalgic encephalomyelitis: an updated systematic review. J R Soc Med. 2006 Oct; 99(10):506-20. PMID: 17021301.
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    61. Rodgers MA, Hempel S, Aho T, Kelly JD, Kleijnen J, Westwood M. Diagnostic tests used in the investigation of adult haematuria: A systematic review. BJU Int. 2006 Dec; 98(6):1154-60. PMID: 16879444.
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    62. Eichler K, Hempel S, Wilby J, Myers L, Bachmann LM, Kleijnen J. Diagnostic value of systematic biopsy methods in the investigation of prostate cancer: a systematic review. J Urol. 2006 May; 175(5):1605-12. PMID: 16600713.
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    63. Carlsson LE, Hempel S, Greinacher A. Iron deficiency anaemia in young women. Eur J Haematol. 2002 Jun; 68(6):341-4. PMID: 12225391.
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    64. Hempel SL, Buettner GR, O'Malley YQ, Wessels DA, Flaherty DM. Dihydrofluorescein diacetate is superior for detecting intracellular oxidants: comparison with 2',7'-dichlorodihydrofluorescein diacetate, 5(and 6)-carboxy-2',7'-dichlorodihydrofluorescein diacetate, and dihydrorhodamine 123. Free Radic Biol Med. 1999 Jul; 27(1-2):146-59. PMID: 10443931.
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    65. Wessels DA, Hempel SL. Ibuprofen protects human endothelial cell prostaglandin H synthase from hydrogen peroxide. Am J Physiol. 1996 Dec; 271(6 Pt 1):C1879-86. PMID: 8997188.
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    66. Hempel SL, Elliott DE. Chest pain in an aspirin-sensitive asthmatic patient. Eosinophilic esophagitis causing esophageal dysmotility. Chest. 1996 Oct; 110(4):1117-20. PMID: 8874281.
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    67. Hempel SL, Buettner GR, Wessels DA, Galvan GM, O'Malley YQ. Extracellular iron (II) can protect cells from hydrogen peroxide. Arch Biochem Biophys. 1996 Jun 15; 330(2):401-8. PMID: 8660671.
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