Max Andrew Thorwald

Title(s)Research Associate
SchoolSchool of Gerontology
AddressGER 313D
University Park Campus
Los Angeles CA 90089
Phone+1 213 740 0809
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Beyond genes and environment: mapping biological stochasticity in aging. Geroscience. 2025 Apr 29. Hruby AJ, Garcia G, Thorwald MA, Finch CE, Johnson J, Higuchi-Sanabria R. PMID: 40301228.
      View in: PubMed   Mentions:    Fields:    
    2. Down syndrome with Alzheimer's disease brains have increased iron and associated lipid peroxidation consistent with ferroptosis. bioRxiv. 2025 Feb 06. Thorwald MA, Godoy-Lugo JA, Kerstiens E, Garcia G, Kim M, Shemtov SJ, Silva J, Durra S, O'Day PA, Mack WJ, Hiniker A, Vermulst M, Benayoun BA, Higuchi-Sanabria R, Forman HJ, Head E, Finch CE. PMID: 39975068; PMCID: PMC11839036.
      View in: PubMed   Mentions:
    3. Iron chelation by oral deferoxamine treatment decreased brain iron and iron signaling proteins. J Alzheimers Dis. 2025 Feb; 103(4):1180-1190. Thorwald MA, Sta Maria NS, Chakhoyan A, O'Day PA, Jacobs RE, Zlokovic B, Finch CE. PMID: 39894909.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    4. Iron-associated lipid peroxidation in Alzheimer's disease is increased in lipid rafts with decreased ferroptosis suppressors, tested by chelation in mice. Alzheimers Dement. 2025 Jan; 21(1):e14541. Thorwald MA, Godoy-Lugo JA, Garcia G, Silva J, Kim M, Christensen A, Mack WJ, Head E, O'Day PA, Benayoun BA, Morgan TE, Pike CJ, Higuchi-Sanabria R, Forman HJ, Finch CE. PMID: 39876821; PMCID: PMC11775463.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    5. Transcript errors generate amyloid-like proteins in huwman cells. Nat Commun. 2024 10 07; 15(1):8676. Chung CS, Kou Y, Shemtov SJ, Verheijen BM, Flores I, Love K, Del Dosso A, Thorwald MA, Liu Y, Hicks D, Sun Y, Toney RG, Carrillo L, Nguyen MM, Biao H, Jin Y, Jauregui AM, Quiroz JD, Head E, Moore DL, Simpson S, Thomas KW, Coba MP, Li Z, Benayoun BA, Rosenthal JJC, Kennedy SR, Quadrato G, Gout JF, Chen L, Vermulst M. PMID: 39375347; PMCID: PMC11458900.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    6. Activation of the muscle-to-brain axis ameliorates neurocognitive deficits in an Alzheimer's disease mouse model via enhancing neurotrophic and synaptic signaling. Geroscience. 2025 Apr; 47(2):1593-1613. Taha HB, Birnbaum A, Matthews I, Aceituno K, Leon J, Thorwald M, Godoy-Lugo J, Cortes CJ. PMID: 39269584; PMCID: PMC11978596.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    7. Iron chelation by oral deferoxamine treatment decreased brain iron and iron signaling proteins. bioRxiv. 2024 Aug 17. Thorwald MA, Godoy-Lugo JA, Santa Maria N, Chakhoyan A, O'Day P, Jacobs R, Zlokovic B, Finch C. PMID: 39211245; PMCID: PMC11361199.
      View in: PubMed   Mentions:
    8. Air pollution amyloidogenesis is attenuated by the gamma-secretase modulator GSM-15606. Alzheimers Dement. 2024 Sep; 20(9):6107-6114. Godoy-Lugo JA, Thorwald MA, Cacciottolo M, D'Agostino C, Chakhoyan A, Sioutas C, Tanzi RE, Rynearson KD, Finch CE. PMID: 39132765; PMCID: PMC11497728.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsPHPublic Health
    9. Inhaled Pollutants of the Gero-Exposome and Later-Life Health. J Gerontol A Biol Sci Med Sci. 2024 Jul 01; 79(7). Finch CE, Thorwald MA. PMID: 38644649; PMCID: PMC11170295.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    10. Iron associated lipid peroxidation in Alzheimers disease is increased in lipid rafts with decreased ferroptosis suppressors, tested by chelation in mice. bioRxiv. 2024 Jun 13. Thorwald M, Godoy-Lugo JA, Garcia G, Silva J, Kim M, Christensen A, Mack WJ, Head E, O'Day PA, Benayoun BA, Morgan TE, Pike CJ, Higuchi-Sanabria R, Forman HJ, Finch CE. PMID: 37034750; PMCID: PMC10081222.
      View in: PubMed   Mentions:
    11. Investigating impacts of the mycothiazole chemotype as a chemical probe for the study of mitochondrial function and aging. Geroscience. 2024 Dec; 46(6):6009-6028. Dutta N, Gerke JA, Odron SF, Morris JD, Hruby A, Kim J, Torres TC, Shemtov SJ, Clarke JG, Chang MC, Shaghasi H, Ray MN, Averbukh M, Hoang S, Oorloff M, Alcala A, Vega M, Mehta HH, Thorwald MA, Crews P, Vermulst M, Garcia G, Johnson TA, Higuchi-Sanabria R. PMID: 38570396; PMCID: PMC11493899.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    12. Protection against APOE4 -associated aging phenotypes with the longevity-promoting intervention 17α-estradiol in male mice. bioRxiv. 2024 Mar 14. McGill CJ, Christensen A, Qian W, Thorwald MA, Lugo JG, Namvari S, White OS, Finch CE, Benayoun BA, Pike CJ. PMID: 38559059; PMCID: PMC10980056.
      View in: PubMed   Mentions:
    13. Microglial TLR4 Mediates White Matter Injury in a Combined Model of Diesel Exhaust Exposure and Cerebral Hypoperfusion. Stroke. 2024 Apr; 55(4):1090-1093. Shkirkova K, Demetriou AN, Sizdahkhani S, Lamorie-Foote K, Zhang H, Morales M, Chen S, Zhao L, Diaz A, Godoy-Lugo JA, Zhou B, Zhang N, Li A, Mack WJ, Sioutas C, Thorwald MA, Finch CE, Pike C, Mack WJ. PMID: 38299349; PMCID: PMC10978264.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    14. Investigating impacts of marine sponge derived mycothiazole and its acetylated derivative on mitochondrial function and aging. bioRxiv. 2023 Nov 27. Dutta N, Gerke JA, Odron SF, Morris JD, Hruby A, Castro Torres T, Shemtov SJ, Clarke JG, Chang MC, Shaghasi H, Ray MN, Averbukh M, Hoang S, Oorloff M, Alcala A, Vega M, Mehta HH, Thorwald MA, Crews P, Vermulst M, Garcia G, Johnson TA, Higuchi-Sanabria R. PMID: 38077060; PMCID: PMC10705228.
      View in: PubMed   Mentions:
    15. Air pollution nanoparticle and alpha-synuclein fibrils synergistically decrease glutamate receptor A1, depending upon nPM batch activity. Heliyon. 2023 Apr; 9(4):e15622. Zhang H, D'Agostino C, Tulisiak C, Thorwald MA, Bergkvist L, Lindquist A, Meyerdirk L, Schulz E, Becker K, Steiner JA, Cacciottolo M, Kwatra M, Rey NL, Escobar Galvis ML, Ma J, Sioutas C, Morgan TE, Finch CE, Brundin P. PMID: 37128335; PMCID: PMC10148131.
      View in: PubMed   Mentions: 4  
    16. A tale of two pathways: Regulation of proteostasis by UPRmt and MDPs. Curr Opin Neurobiol. 2023 02; 78:102673. Johns A, Higuchi-Sanabria R, Thorwald MA, Vilchez D. PMID: 36621224; PMCID: PMC9845188.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    17. Amyloid futures in the expanding pathology of brain aging and dementia. Alzheimers Dement. 2023 06; 19(6):2605-2617. Thorwald MA, Silva J, Head E, Finch CE. PMID: 36536382; PMCID: PMC10271937.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    18. Angiotensin receptor blockade with olmesartan alleviates brain pathology in obese OLETF rats. Clin Exp Pharmacol Physiol. 2023 03; 50(3):228-237. Rodriguez-Ortiz CJ, Thorwald MA, Rodriguez R, Mejias-Ortega M, Kieu Z, Maitra N, Hawkins C, Valenzuela J, Peng M, Nishiyama A, Ortiz RM, Kitazawa M. PMID: 36398458; PMCID: PMC9898104.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    19. Large-scale genetic screens identify BET-1 as a cytoskeleton regulator promoting actin function and life span. Aging Cell. 2023 01; 22(1):e13742. Garcia G, Bar-Ziv R, Averbukh M, Dasgupta N, Dutta N, Zhang H, Fan W, Moaddeli D, Tsui CK, Castro Torres T, Alcala A, Moehle EA, Hoang S, Shalem O, Adams PD, Thorwald MA, Higuchi-Sanabria R. PMID: 36404134; PMCID: PMC9835578.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    20. Glucose Increases Hepatic Mitochondrial Antioxidant Enzyme Activities in Insulin Resistant Rats Following Chronic Angiotensin Receptor Blockade. Int J Mol Sci. 2022 Sep 17; 23(18). Godoy-Lugo JA, Thorwald MA, Mendez DA, Rodriguez R, Nakano D, Nishiyama A, Ortiz RM. PMID: 36142809; PMCID: PMC9505141.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    21. Cardiac NF-κB Acetylation Increases While Nrf2-Related Gene Expression and Mitochondrial Activity Are Impaired during the Progression of Diabetes in UCD-T2DM Rats. Antioxidants (Basel). 2022 May 09; 11(5). Thorwald MA, Godoy-Lugo JA, Rodriguez R, Stanhope KL, Graham JL, Havel PJ, Forman HJ, Ortiz RM. PMID: 35624791; PMCID: PMC9137621.
      View in: PubMed   Mentions: 5  
    22. Neurotoxicity of Diesel Exhaust Particles. J Alzheimers Dis. 2022; 89(4):1263-1278. Shkirkova K, Lamorie-Foote K, Zhang N, Li A, Diaz A, Liu Q, Thorwald MA, Godoy-Lugo JA, Ge B, D'Agostino C, Zhang Z, Mack WJ, Sioutas C, Finch CE, Mack WJ, Zhang H. PMID: 36031897.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    23. Chronic angiotensin receptor activation promotes hepatic triacylglycerol accumulation during an acute glucose challenge in obese-insulin-resistant OLETF rats. Endocrine. 2022 Jan; 75(1):92-107. Godoy-Lugo JA, Thorwald MA, Hui DY, Nishiyama A, Nakano D, Soñanez-Organis JG, Ortiz RM. PMID: 34327606; PMCID: PMC8763929.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    24. Urban Air Pollution Nanoparticles from Los Angeles: Recently Decreased Neurotoxicity. J Alzheimers Dis. 2021; 82(1):307-316. Zhang H, D'Agostino C, Forman HJ, Cacciottolo M, Thorwald M, Mack WJ, Liu Q, Shkirkova K, Lamorie-Foote K, Sioutas C, Pirhadi M, Mack WJ, Morgan TE, Finch CE. PMID: 33967042.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    25. The APOE gene cluster responds to air pollution factors in mice with coordinated expression of genes that differs by age in humans. Alzheimers Dement. 2021 02; 17(2):175-190. Haghani A, Thorwald M, Morgan TE, Finch CE. PMID: 33215813; PMCID: PMC7914175.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsPHPublic Health
    26. Mouse brain transcriptome responses to inhaled nanoparticulate matter differed by sex and APOE in Nrf2-Nfkb interactions. Elife. 2020 06 24; 9. Haghani A, Cacciottolo M, Doty KR, D'Agostino C, Thorwald M, Safi N, Levine ME, Sioutas C, Town TC, Forman HJ, Zhang H, Morgan TE, Finch CE. PMID: 32579111; PMCID: PMC7314548.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    27. Comparison of hand-held acoustic Doppler with point-of-care portable color Doppler ultrasound in the assessment of venous reflux disease. J Vasc Surg Venous Lymphat Disord. 2020 09; 8(5):831-839.e2. Dhillon J, Thorwald M, Chung S, Maloney G, Srivatsa S. PMID: 32184080.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    28. Toxicity of urban air pollution particulate matter in developing and adult mouse brain: Comparison of total and filter-eluted nanoparticles. Environ Int. 2020 03; 136:105510. Haghani A, Johnson R, Safi N, Zhang H, Thorwald M, Mousavi A, Woodward NC, Shirmohammadi F, Coussa V, Wise JP, Forman HJ, Sioutas C, Allayee H, Morgan TE, Finch CE. PMID: 32004873; PMCID: PMC7063839.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsPHPublic Health
    29. Simultaneous angiotensin receptor blockade and glucagon-like peptide-1 receptor activation ameliorate albuminuria in obese insulin-resistant rats. Clin Exp Pharmacol Physiol. 2020 03; 47(3):422-431. Rodriguez R, Escobedo B, Lee AY, Thorwald M, Godoy-Lugo JA, Nakano D, Nishiyama A, Parkes DG, Ortiz RM. PMID: 31675433.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    30. Nrf2-related gene expression is impaired during a glucose challenge in type II diabetic rat hearts. Free Radic Biol Med. 2019 01; 130:306-317. Thorwald MA, Godoy-Lugo JA, Rodriguez GJ, Rodriguez MA, Jamal M, Kinoshita H, Nakano D, Nishiyama A, Forman HJ, Ortiz RM. PMID: 30316779.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    31. Glucoregulatory and Cardiometabolic Profiles of Almond vs. Cracker Snacking for 8 Weeks in Young Adults: A Randomized Controlled Trial. Nutrients. 2018 Jul 25; 10(8). Dhillon J, Thorwald M, De La Cruz N, Vu E, Asghar SA, Kuse Q, Diaz Rios LK, Ortiz RM. PMID: 30044438; PMCID: PMC6115851.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    32. Angiotensin receptor and tumor necrosis factor-α activation contributes to glucose intolerance independent of systolic blood pressure in obese rats. Am J Physiol Renal Physiol. 2018 10 01; 315(4):F1081-F1090. Rodriguez R, Lee A, Mathis KW, Broome HJ, Thorwald M, Martinez B, Nakano D, Nishiyama A, Ryan MJ, Ortiz RM. PMID: 29993275; PMCID: PMC6230730.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    33. Angiotensin receptor blockade improves cardiac mitochondrial activity in response to an acute glucose load in obese insulin resistant rats. Redox Biol. 2018 04; 14:371-378. Thorwald M, Rodriguez R, Lee A, Martinez B, Peti-Peterdi J, Nakano D, Nishiyama A, Ortiz RM. PMID: 29049981; PMCID: PMC5647524.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    34. Angiotensin and mineralocorticoid receptor antagonism attenuates cardiac oxidative stress in angiotensin II-infused rats. Clin Exp Pharmacol Physiol. 2015 Nov; 42(11):1178-88. Minas JN, Thorwald MA, Conte D, Vázquez-Medina JP, Nishiyama A, Ortiz RM. PMID: 26234762; PMCID: PMC4596772.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    35. Angiotensin receptor-mediated oxidative stress is associated with impaired cardiac redox signaling and mitochondrial function in insulin-resistant rats. Am J Physiol Heart Circ Physiol. 2013 Aug 15; 305(4):H599-607. Vázquez-Medina JP, Popovich I, Thorwald MA, Viscarra JA, Rodriguez R, Sonanez-Organis JG, Lam L, Peti-Peterdi J, Nakano D, Nishiyama A, Ortiz RM. PMID: 23771688; PMCID: PMC3891241.
      View in: PubMed   Mentions: 30     Fields:    
    36. Angiotensin receptor blockade recovers hepatic UCP2 expression and aconitase and SDH activities and ameliorates hepatic oxidative damage in insulin resistant rats. Endocrinology. 2012 Dec; 153(12):5746-59. Montez P, Vázquez-Medina JP, Rodríguez R, Thorwald MA, Viscarra JA, Lam L, Peti-Peterdi J, Nakano D, Nishiyama A, Ortiz RM. PMID: 23087176; PMCID: PMC3512060.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
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