Loading...

Giorgia Quadrato

Title(s)Assistant Professor of Stem Cell Biology and Regenerative Medicine
Address1425 San Pablo Street
Health Sciences Campus
Los Angeles CA 90033
vCardDownload vCard

    Collapse Overview 
    Collapse Overview
    Dr. Quadrato's laboratory focuses on understanding the cellular and molecular basis of human brain development and disease. By combining the use of emerging models of the human brain with single cell omics approaches, the laboratory is aiming to identify cell type specific disease mechanisms, and above all, new treatments for human neurodevelopmental disorders.

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Taming human brain organoids one cell at a time. Semin Cell Dev Biol. 2020 Jul 24. Atamian A, Cordón-Barris L, Quadrato G. PMID: 32718852.
      View in: PubMed   Mentions:    Fields:    
    2. Guiding human development in a dish. Nat Methods. 2019 07; 16(7):585-586. Morsut L, Quadrato G. PMID: 31249404.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. Individual brain organoids reproducibly form cell diversity of the human cerebral cortex. Nature. 2019 06; 570(7762):523-527. Velasco S, Kedaigle AJ, Simmons SK, Nash A, Rocha M, Quadrato G, Paulsen B, Nguyen L, Adiconis X, Regev A, Levin JZ, Arlotta P. PMID: 31168097.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    4. Studying the Brain in a Dish: 3D Cell Culture Models of Human Brain Development and Disease. Curr Top Dev Biol. 2018; 129:99-122. Brown J, Quadrato G, Arlotta P. PMID: 29801532.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    5. Present and future of modeling human brain development in 3D organoids. Curr Opin Cell Biol. 2017 12; 49:47-52. Quadrato G, Arlotta P. PMID: 29227864.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    6. Cell diversity and network dynamics in photosensitive human brain organoids. Nature. 2017 05 04; 545(7652):48-53. Quadrato G, Nguyen T, Macosko EZ, Sherwood JL, Min Yang S, Berger DR, Maria N, Scholvin J, Goldman M, Kinney JP, Boyden ES, Lichtman JW, Williams ZM, McCarroll SA, Arlotta P. PMID: 28445462.
      View in: PubMed   Mentions: 108     Fields:    Translation:HumansCells
    7. The promises and challenges of human brain organoids as models of neuropsychiatric disease. Nat Med. 2016 11; 22(11):1220-1228. Quadrato G, Brown J, Arlotta P. PMID: 27783065.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    8. Stressed out? Healing Tips for Newly Reprogrammed Neurons. Cell Stem Cell. 2016 Mar 03; 18(3):297-9. Quadrato G, Zhang AC, Arlotta P. PMID: 26942845.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    9. The MDM4/MDM2-p53-IGF1 axis controls axonal regeneration, sprouting and functional recovery after CNS injury. Brain. 2015 Jul; 138(Pt 7):1843-62. Joshi Y, Sória MG, Quadrato G, Inak G, Zhou L, Hervera A, Rathore KI, Elnaggar M, Cucchiarini M, Magali C, Marine JC, Puttagunta R, Di Giovanni S. PMID: 25981963.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    10. Direct cell-cell contact with the vascular niche maintains quiescent neural stem cells. Nat Cell Biol. 2014 Nov; 16(11):1045-56. Ottone C, Krusche B, Whitby A, Clements M, Quadrato G, Pitulescu ME, Adams RH, Parrinello S. PMID: 25283993.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansAnimalsCells
    11. Modulation of GABAA receptor signaling increases neurogenesis and suppresses anxiety through NFATc4. J Neurosci. 2014 Jun 18; 34(25):8630-45. Quadrato G, Elnaggar MY, Duman C, Sabino A, Forsberg K, Di Giovanni S. PMID: 24948817.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    12. Adult neurogenesis in brain repair: cellular plasticity vs. cellular replacement. Front Neurosci. 2014; 8:17. Quadrato G, Elnaggar MY, Di Giovanni S. PMID: 24574955.
      View in: PubMed   Mentions:
    13. The tumor suppressor p53 fine-tunes reactive oxygen species levels and neurogenesis via PI3 kinase signaling. J Neurosci. 2013 Sep 04; 33(36):14318-30. Forsberg K, Wuttke A, Quadrato G, Chumakov PM, Wizenmann A, Di Giovanni S. PMID: 24005285.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    14. p53 Regulates the neuronal intrinsic and extrinsic responses affecting the recovery of motor function following spinal cord injury. J Neurosci. 2012 Oct 03; 32(40):13956-70. Floriddia EM, Rathore KI, Tedeschi A, Quadrato G, Wuttke A, Lueckmann JM, Kigerl KA, Popovich PG, Di Giovanni S. PMID: 23035104.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    15. Waking up the sleepers: shared transcriptional pathways in axonal regeneration and neurogenesis. Cell Mol Life Sci. 2013 Mar; 70(6):993-1007. Quadrato G, Di Giovanni S. PMID: 22899311.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    16. Neural regeneration: lessons from regenerating and non-regenerating systems. Mol Neurobiol. 2012 Oct; 46(2):227-41. Ferreira LM, Floriddia EM, Quadrato G, Di Giovanni S. PMID: 22717989.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    17. Nuclear factor of activated T cells (NFATc4) is required for BDNF-dependent survival of adult-born neurons and spatial memory formation in the hippocampus. Proc Natl Acad Sci U S A. 2012 Jun 05; 109(23):E1499-508. Quadrato G, Benevento M, Alber S, Jacob C, Floriddia EM, Nguyen T, Elnaggar MY, Pedroarena CM, Molkentin JD, Di Giovanni S. PMID: 22586092.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    18. Gatekeeper between quiescence and differentiation: p53 in axonal outgrowth and neurogenesis. Int Rev Neurobiol. 2012; 105:71-89. Quadrato G, Di Giovanni S. PMID: 23206596.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    19. Constitutive activity of cannabinoid-2 (CB2) receptors plays an essential role in the protean agonism of (+)AM1241 and L768242. Br J Pharmacol. 2009 Sep; 158(1):382-91. Mancini I, Brusa R, Quadrato G, Foglia C, Scandroglio P, Silverman LS, Tulshian D, Reggiani A, Beltramo M. PMID: 19552692.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    20. Impaired adult neurogenesis associated with short-term memory defects in NF-kappaB p50-deficient mice. J Neurosci. 2008 Apr 09; 28(15):3911-9. Denis-Donini S, Dellarole A, Crociara P, Francese MT, Bortolotto V, Quadrato G, Canonico PL, Orsetti M, Ghi P, Memo M, Bonini SA, Ferrari-Toninelli G, Grilli M. PMID: 18400889.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    Giorgia's Networks
    Concepts (140)
    Derived automatically from this person's publications.
    _
    Co-Authors (3)
    People in Profiles who have published with this person.
    _
    Similar People (60)
    People who share similar concepts with this person.
    _
    Same Department
    Search Department
    _