Marcella Birtele

Title(s)Postdoctoral Scholar - Research Associate
SchoolKeck School of Medicine of Usc
Address1425 San Pablo St.
Health Sciences Campus
Los Angeles CA 90033
Phone+1 323 442 0415
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Modelling human brain development and disease with organoids. Nat Rev Mol Cell Biol. 2025 May; 26(5):389-412. Birtele M, Lancaster M, Quadrato G. PMID: 39668188.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    2. Generation and long-term culture of human cerebellar organoids from pluripotent stem cells. Nat Protoc. 2024 Dec 02. Atamian A, Birtele M, Hosseini N, Quadrato G. PMID: 39623220.
      View in: PubMed   Mentions:    Fields:    
    3. Pathway to independence: perspectives on the future. Development. 2024 Oct 01; 151(19). Birtele M, Cerise M, Djenoune L, Kale G, Maniou E, Prahl LS, Schuster K, Villeneuve C. PMID: 39369305.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    4. Human cerebellar organoids with functional Purkinje cells. Cell Stem Cell. 2024 01 04; 31(1):39-51.e6. Atamian A, Birtele M, Hosseini N, Nguyen T, Seth A, Del Dosso A, Paul S, Tedeschi N, Taylor R, Coba MP, Samarasinghe R, Lois C, Quadrato G. PMID: 38181749; PMCID: PMC11417151.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    5. Non-synaptic function of the autism spectrum disorder-associated gene SYNGAP1 in cortical neurogenesis. Nat Neurosci. 2023 Dec; 26(12):2090-2103. Birtele M, Del Dosso A, Xu T, Nguyen T, Wilkinson B, Hosseini N, Nguyen S, Urenda JP, Knight G, Rojas C, Flores I, Atamian A, Moore R, Sharma R, Pirrotte P, Ashton RS, Huang EJ, Rumbaugh G, Coba MP, Quadrato G. PMID: 37946050; PMCID: PMC11349286.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    6. Present and Future Modeling of Human Psychiatric Connectopathies With Brain Organoids. Biol Psychiatry. 2023 04 01; 93(7):606-615. Urenda JP, Del Dosso A, Birtele M, Quadrato G. PMID: 36759258; PMCID: PMC11229385.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    7. Single-cell transcriptional and functional analysis of dopaminergic neurons in organoid-like cultures derived from human fetal midbrain. Development. 2022 12 01; 149(23). Birtele M, Storm P, Sharma Y, Kajtez J, Wahlestedt JN, Sozzi E, Nilsson F, Stott S, He XL, Mattsson B, Ottosson DR, Barker RA, Fiorenzano A, Parmar M. PMID: 36305490; PMCID: PMC10114107.
      View in: PubMed   Mentions: 11     Fields:    
    8. Silk scaffolding drives self-assembly of functional and mature human brain organoids. Front Cell Dev Biol. 2022; 10:1023279. Sozzi E, Kajtez J, Bruzelius A, Wesseler MF, Nilsson F, Birtele M, Larsen NB, Ottosson DR, Storm P, Parmar M, Fiorenzano A. PMID: 36313550; PMCID: PMC9614032.
      View in: PubMed   Mentions: 10  
    9. Age-related pathological impairments in directly reprogrammed dopaminergic neurons derived from patients with idiopathic Parkinson's disease. Stem Cell Reports. 2022 10 11; 17(10):2203-2219. Drouin-Ouellet J, Legault EM, Nilsson F, Pircs K, Bouquety J, Petit F, Shrigley S, Birtele M, Pereira M, Storm P, Sharma Y, Bruzelius A, Vuono R, Kele M, Stoker TB, Ottosson DR, Falk A, Jakobsson J, Barker RA, Parmar M. PMID: 36150382; PMCID: PMC9561608.
      View in: PubMed   Mentions: 14     Fields:    
    10. Embedded 3D Printing in Self-Healing Annealable Composites for Precise Patterning of Functionally Mature Human Neural Constructs. Adv Sci (Weinh). 2022 09; 9(25):e2201392. Kajtez J, Wesseler MF, Birtele M, Khorasgani FR, Rylander Ottosson D, Heiskanen A, Kamperman T, Leijten J, Martínez-Serrano A, Larsen NB, Angelini TE, Parmar M, Lind JU, Emnéus J. PMID: 35712780; PMCID: PMC9443452.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    11. Author Correction: Single-cell transcriptomics captures features of human midbrain development and dopamine neuron diversity in brain organoids. Nat Commun. 2022 Jun 08; 13(1):3312. Fiorenzano A, Sozzi E, Birtele M, Kajtez J, Giacomoni J, Nilsson F, Bruzelius A, Sharma Y, Zhang Y, Mattsson B, Emnéus J, Ottosson DR, Storm P, Parmar M. PMID: 35676291; PMCID: PMC9177537.
      View in: PubMed   Mentions: 1     Fields:    
    12. Not all cortical organoids are created equal. Nat Cell Biol. 2022 06; 24(6):805-806. Atamian A, Birtele M, Quadrato G. PMID: 35697780; PMCID: PMC11216691.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    13. Single-cell transcriptomics captures features of human midbrain development and dopamine neuron diversity in brain organoids. Nat Commun. 2021 12 15; 12(1):7302. Fiorenzano A, Sozzi E, Birtele M, Kajtez J, Giacomoni J, Nilsson F, Bruzelius A, Sharma Y, Zhang Y, Mattsson B, Emnéus J, Ottosson DR, Storm P, Parmar M. PMID: 34911939; PMCID: PMC8674361.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    14. 3D-Printed Soft Lithography for Complex Compartmentalized Microfluidic Neural Devices. Adv Sci (Weinh). 2021 Jun; 8(12):e2101787. Kajtez J, Buchmann S, Vasudevan S, Birtele M, Rocchetti S, Pless CJ, Heiskanen A, Barker RA, Martínez-Serrano A, Parmar M, Lind JU, Emnéus J. PMID: 34165904; PMCID: PMC8224456.
      View in: PubMed   Mentions: 2     Fields:    
    15. Evaluation of TH-Cre knock-in cell lines for detection and specific targeting of stem cell-derived dopaminergic neurons. Heliyon. 2021 Jan; 7(1):e06006. Fiorenzano A, Birtele M, Wahlestedt JN, Parmar M. PMID: 33532642; PMCID: PMC7821040.
      View in: PubMed   Mentions: 4  
    16. Single-Cell Profiling of Coding and Noncoding Genes in Human Dopamine Neuron Differentiation. Cells. 2021 01 12; 10(1). Nilsson F, Storm P, Sozzi E, Hidalgo Gil D, Birtele M, Sharma Y, Parmar M, Fiorenzano A. PMID: 33445654; PMCID: PMC7827700.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    17. Direct Reprogramming of Human Fetal- and Stem Cell-Derived Glial Progenitor Cells into Midbrain Dopaminergic Neurons. Stem Cell Reports. 2020 10 13; 15(4):869-882. Nolbrant S, Giacomoni J, Hoban DB, Bruzelius A, Birtele M, Chandler-Militello D, Pereira M, Ottosson DR, Goldman SA, Parmar M. PMID: 32976765; PMCID: PMC7562948.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    18. Author Correction: Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson's disease. Nat Commun. 2020 07 15; 11(1):3630. Tiklová K, Nolbrant S, Fiorenzano A, Björklund ÅK, Sharma Y, Heuer A, Gillberg L, Hoban DB, Cardoso T, Adler AF, Birtele M, Lundén-Miguel H, Volakakis N, Kirkeby A, Perlmann T, Parmar M. PMID: 32669619; PMCID: PMC7363905.
      View in: PubMed   Mentions: 4     Fields:    
    19. 3D-Printed Soft Lithography for Complex Compartmentalized Microfluidic Neural Devices. Adv Sci (Weinh). 2020 Aug; 7(16):2001150. Kajtez J, Buchmann S, Vasudevan S, Birtele M, Rocchetti S, Pless CJ, Heiskanen A, Barker RA, Martínez-Serrano A, Parmar M, Lind JU, Emnéus J. PMID: 32832365; PMCID: PMC7435242.
      View in: PubMed   Mentions: 22     Fields:    
    20. Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson's disease. Nat Commun. 2020 05 15; 11(1):2434. Tiklová K, Nolbrant S, Fiorenzano A, Björklund ÅK, Sharma Y, Heuer A, Gillberg L, Hoban DB, Cardoso T, Adler AF, Birtele M, Lundén-Miguel H, Volakakis N, Kirkeby A, Perlmann T, Parmar M. PMID: 32415072; PMCID: PMC7229159.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimalsCells
    21. Dual modulation of neuron-specific microRNAs and the REST complex promotes functional maturation of human adult induced neurons. FEBS Lett. 2019 12; 593(23):3370-3380. Birtele M, Sharma Y, Kidnapillai S, Lau S, Stoker TB, Barker RA, Rylander Ottosson D, Drouin-Ouellet J, Parmar M. PMID: 31535361.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    22. Direct reprogramming into interneurons: potential for brain repair. Cell Mol Life Sci. 2019 Oct; 76(20):3953-3967. Pereira M, Birtele M, Rylander Ottosson D. PMID: 31250034; PMCID: PMC6785593.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    23. In Vivo Direct Reprogramming of Resident Glial Cells into Interneurons by Intracerebral Injection of Viral Vectors. J Vis Exp. 2019 06 17; (148). Pereira M, Birtele M, Rylander Ottosson D. PMID: 31259901.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    24. Direct Reprogramming of Resident NG2 Glia into Neurons with Properties of Fast-Spiking Parvalbumin-Containing Interneurons. Stem Cell Reports. 2017 09 12; 9(3):742-751. Pereira M, Birtele M, Shrigley S, Benitez JA, Hedlund E, Parmar M, Ottosson DR. PMID: 28844658; PMCID: PMC5599255.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
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    NIH Funding Acknowledgment: Important - All publications resulting from the utilization of SC CTSI resources are required to credit the SC CTSI grant by including the NIH funding acknowledgment and must comply with the NIH Public Access Policy.

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