Lucy Mary Golden, PhD

Title(s)Professor of Clinical Medicine
SchoolKeck School of Medicine of Usc
AddressNOR 4501
Health Sciences Campus
Los Angeles CA 90033
Phone+1 323 442 1319
ORCID ORCID Icon0000-0002-2087-4405 Additional info
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    Mechanisms of Advanced NAFLD Disparities in Hispanics: A Multi-level Analysis
    NIH/NIMHD R01MD015971Jan 1, 2021 - Nov 30, 2025
    Role: Co-I
    Description: Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in modern society. NAFLD is predicted to become the leading indication for liver transplantation and is a risk factor for the development of hepatocellular carcinoma that can develop even without cirrhosis. In a large Hispanic and non- Hispanic White population with unequivocally staged levels of fibrosis, we will combine state-of-the-art approaches (e.g., lifestyle and environmental factors, unbiased genetic variation analyses, single-cell transcriptomic analyses of peripheral innate immune cells resulting in identification of diagnostic protein biomarkers, and structural integrated analyses) to gain novel mechanistic insights into NAFLD disparities in Hispanics and disease progression to fibrosis which is the single most important predictor of outcome.
    Innate Immunity, Cholesterol, and NASH Pathogenesis
    NIH/NIDDK R01DK117004Jan 20, 2020 - Dec 31, 2023
    Role: PI
    Description: Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in modern society. NAFLD is predicted to become the leading indication for liver transplantation and is a risk factor for the development of hepatocellular carcinoma that can develop even without cirrhosis. The lack of evidence-based, FDA-approved treatment options for NASH underscores the need for further research into understanding disease pathogenesis and identifying potential targets. Here, based on compelling preliminary and recently published data from our group, we propose to comprehensively study how the innate immune response mediates inflammation and fibrosis in mice and humans with NAFLD, providing novel insights into potential therapeutic targets.
    Global liver specific gene expression changes induced by PFAS and risk of liver cancer
    Southern California Environmental Health Sciences Center SCEHSC Pilot
    Role: C0-PI
    Description: We will combine two state-of-the art technologies (3D liver culture and scRNA- Sequencing) to establish a robust physiologically relevant model to test not only the effects of PFAS chemicals on human liver, but this model will also prove useful to screen other damaging agents as well as potential therapeutics. We will generate a high-resolution data set on human liver responses to important legacy and replacement PFAS chemicals. The pilot project will provide us with insights and preliminary data into the relationship between biological pathways in the liver and environmental pollutants and will form the basis for an R01 application. In the R01 submission, we plan to expand the analysis of human study to include NAFLD and cirrhosis cases in the MEC and samples from other cohorts.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Autophagy impairment in liver CD11c+ cells promotes non-alcoholic fatty liver disease through production of IL-23. Nat Commun. 2022 03 17; 13(1):1440. Galle-Treger L, Helou DG, Quach C, Howard E, Hurrell BP, Muench GRA, Shafiei-Jahani P, Painter JD, Iorga A, Dara L, Emamaullee J, Golden-Mason L, Rosen HR, Soroosh P, Akbari O. PMID: 35301333; PMCID: PMC8931085.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    2. In Utero Exposure to Mercury Is Associated With Increased Susceptibility to Liver Injury and Inflammation in Childhood. Hepatology. 2021 09; 74(3):1546-1559. Stratakis N, Golden-Mason L, Margetaki K, Zhao Y, Valvi D, Garcia E, Maitre L, Andrusaityte S, Basagana X, Borràs E, Bustamante M, Casas M, Fossati S, Grazuleviciene R, Haug LS, Heude B, McEachan RRC, Meltzer HM, Papadopoulou E, Roumeliotaki T, Robinson O, Sabidó E, Urquiza J, Vafeiadi M, Varo N, Wright J, Vos MB, Hu H, Vrijheid M, Berhane KT, Conti DV, McConnell R, Rosen HR, Chatzi L. PMID: 33730435; PMCID: PMC8446089.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansPHPublic Health
    3. Single-cell transcriptomic analyses of T cells in chronic HCV-infected patients dominated by DAA-induced interferon signaling changes. PLoS Pathog. 2021 08; 17(8):e1009799. Burchill MA, Salomon MP, Golden-Mason L, Wieland A, Maretti-Mira AC, Gale M, Rosen HR. PMID: 34370798; PMCID: PMC8376199.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    4. Cholesterol-Induced M4-Like Macrophages Recruit Neutrophils and Induce NETosis. Front Immunol. 2021; 12:671073. Maretti-Mira AC, Golden-Mason L, Salomon MP, Kaplan MJ, Rosen HR. PMID: 34012454; PMCID: PMC8126646.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    5. Cholesterol-binding translocator protein TSPO regulates steatosis and bile acid synthesis in nonalcoholic fatty liver disease. iScience. 2021 May 21; 24(5):102457. Li Y, Chen L, Li L, Sottas C, Petrillo SK, Lazaris A, Metrakos P, Wu H, Ishida Y, Saito T, Golden-Mason L, Rosen HR, Wolff JJ, Silvescu CI, Garza S, Cheung G, Huang T, Fan J, Culty M, Stiles B, Asahina K, Papadopoulos V. PMID: 34013171; PMCID: PMC8113880.
      View in: PubMed   Mentions: 12  
    6. Control of HCV Infection by Natural Killer Cells and Macrophages. Cold Spring Harb Perspect Med. 2020 09 01; 10(9). Rosen HR, Golden-Mason L. PMID: 31871225; PMCID: PMC7447067.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    7. Increased hepatic and circulating chemokine and osteopontin expression occurs early in human NAFLD development. PLoS One. 2020; 15(7):e0236353. Kriss M, Golden-Mason L, Kaplan J, Mirshahi F, Setiawan VW, Sanyal AJ, Rosen HR. PMID: 32730345; PMCID: PMC7392333.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    8. Dietary Lipids Differentially Shape Nonalcoholic Steatohepatitis Progression and the Transcriptome of Kupffer Cells and Infiltrating Macrophages. Hepatology. 2019 07; 70(1):67-83. McGettigan B, McMahan R, Orlicky D, Burchill M, Danhorn T, Francis P, Cheng LL, Golden-Mason L, Jakubzick CV, Rosen HR. PMID: 30516830; PMCID: PMC6923128.
      View in: PubMed   Mentions: 56     Fields:    Translation:AnimalsCells
    9. HCMV jogs the 'memory' of NK cells in HBV. J Hepatol. 2019 03; 70(3):343-345. Gill US, Golden-Mason L. PMID: 30551931; PMCID: PMC6923127.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    10. Revisiting the Paradox of Interferon-Stimulated Gene Expression as a Predictor of Hepatitis C Virus Treatment Response, a Decade Later. Hepatology. 2018 12; 68(6):2053-2055. Golden-Mason L, Rosen HR. PMID: 30055107; PMCID: PMC6923130.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    11. Early and late changes in natural killer cells in response to ledipasvir/sofosbuvir treatment. Hepatol Commun. 2018 04; 2(4):364-375. Golden-Mason L, McMahan RH, Kriss MS, Kilgore AL, Cheng L, Dran RJ, Wieland A, Rosen HR. PMID: 29619416; PMCID: PMC5880201.
      View in: PubMed   Mentions: 17     Fields:    
    12. Hepatocyte-derived exosomes promote T follicular regulatory cell expansion during hepatitis C virus infection. Hepatology. 2018 01; 67(1):71-85. Cobb DA, Kim OK, Golden-Mason L, Rosen HR, Hahn YS. PMID: 28749570; PMCID: PMC5739980.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    13. Galectin-9: Diverse roles in hepatic immune homeostasis and inflammation. Hepatology. 2017 07; 66(1):271-279. Golden-Mason L, Rosen HR. PMID: 28195343; PMCID: PMC5521806.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimals
    14. Neutrophil-to-lymphocyte ratio correlates with proinflammatory neutrophils and predicts death in low model for end-stage liver disease patients with cirrhosis. Liver Transpl. 2017 02; 23(2):155-165. Kalra A, Wedd JP, Bambha KM, Gralla J, Golden-Mason L, Collins C, Rosen HR, Biggins SW. PMID: 28006875; PMCID: PMC5529041.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    15. Correction: Hepatitis C Virus Sensing by Human Trophoblasts Induces Innate Immune Responses and Recruitment of Maternal NK Cells: Potential Implications for Limiting Vertical Transmission. J Immunol. 2017 01 15; 198(2):972. Giugliano S, Petroff MG, Warren BD, Jasti S, Linscheid C, Ward A, Kramer A, Dobrinskikh E, Sheiko MA, Gale M, Golden-Mason L, Winn VD, Rosen HR. PMID: 28069758.
      View in: PubMed   Mentions:    Fields:    
    16. NK cells regulate CXCR2+ neutrophil recruitment during acute lung injury. J Leukoc Biol. 2017 02; 101(2):471-480. Hoegl S, Ehrentraut H, Brodsky KS, Victorino F, Golden-Mason L, Eltzschig HK, McNamee EN. PMID: 27601626; PMCID: PMC5235908.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    17. Hepatitis C Virus-Induced Myeloid-Derived Suppressor Cells Suppress NK Cell IFN-γ Production by Altering Cellular Metabolism via Arginase-1. J Immunol. 2016 Mar 01; 196(5):2283-92. Goh CC, Roggerson KM, Lee HC, Golden-Mason L, Rosen HR, Hahn YS. PMID: 26826241; PMCID: PMC4761460.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansCells
    18. CD4+ and CD8+ T Cell Activation in Children with Hepatitis C. J Pediatr. 2016 Mar; 170:142-8.e1. Sheiko MA, Golden-Mason L, Giugliano S, Hurtado CW, Mack CL, Narkewicz MR, Rosen HR. PMID: 26743497; PMCID: PMC4833455.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    19. Variants in the LGALS9 Gene Are Associated With Development of Liver Disease in Heavy Consumers of Alcohol. Clin Gastroenterol Hepatol. 2016 May; 14(5):762-8.e1. Rosen HR, Golden-Mason L, Daly AK, Yang I, Day CP. PMID: 26598225.
      View in: PubMed   Mentions: 5     Fields:    
    20. HCV-infected cells and differentiation increase monocyte immunoregulatory galectin-9 production. J Leukoc Biol. 2016 Mar; 99(3):495-503. Harwood NM, Golden-Mason L, Cheng L, Rosen HR, Mengshol JA. PMID: 26475932; PMCID: PMC6608045.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    21. Hepatitis C Virus Sensing by Human Trophoblasts Induces Innate Immune Responses and Recruitment of Maternal NK Cells: Potential Implications for Limiting Vertical Transmission. J Immunol. 2015 10 15; 195(8):3737-47. Giugliano S, Petroff MG, Warren BD, Jasti S, Linscheid C, Ward A, Kramer A, Dobrinskikh E, Sheiko MA, Gale M, Golden-Mason L, Winn VD, Rosen HR. PMID: 26342030; PMCID: PMC4592818.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    22. Hepatitis C viral infection is associated with activated cytolytic natural killer cells expressing high levels of T cell immunoglobulin- and mucin-domain-containing molecule-3. Clin Immunol. 2015 May; 158(1):114-25. Golden-Mason L, Waasdorp Hurtado CE, Cheng L, Rosen HR. PMID: 25797693.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    23. Transmitted/founder hepatitis C viruses induce cell-type- and genotype-specific differences in innate signaling within the liver. mBio. 2015 Feb 24; 6(2):e02510. Mitchell AM, Stone AE, Cheng L, Ballinger K, Edwards MG, Stoddard M, Li H, Golden-Mason L, Shaw GM, Khetani S, Rosen HR. PMID: 25714713; PMCID: PMC4357998.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    24. Hepatitis C virus infection induces autocrine interferon signaling by human liver endothelial cells and release of exosomes, which inhibits viral replication. Gastroenterology. 2015 Feb; 148(2):392-402.e13. Giugliano S, Kriss M, Golden-Mason L, Dobrinskikh E, Stone AE, Soto-Gutierrez A, Mitchell A, Khetani SR, Yamane D, Stoddard M, Li H, Shaw GM, Edwards MG, Lemon SM, Gale M, Shah VH, Rosen HR. PMID: 25447848; PMCID: PMC4765499.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCells
    25. Extracellular HCV-core protein induces an immature regulatory phenotype in NK cells: implications for outcome of acute infection. PLoS One. 2014; 9(7):e103219. Golden-Mason L, Hahn YS, Strong M, Cheng L, Rosen HR. PMID: 25076408; PMCID: PMC4116173.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    26. Hepatitis C virus core protein inhibits interferon production by a human plasmacytoid dendritic cell line and dysregulates interferon regulatory factor-7 and signal transducer and activator of transcription (STAT) 1 protein expression. PLoS One. 2014; 9(5):e95627. Stone AE, Mitchell A, Brownell J, Miklin DJ, Golden-Mason L, Polyak SJ, Gale MJ, Rosen HR. PMID: 24788809; PMCID: PMC4006833.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    27. Transmigrating neutrophils shape the mucosal microenvironment through localized oxygen depletion to influence resolution of inflammation. Immunity. 2014 Jan 16; 40(1):66-77. Campbell EL, Bruyninckx WJ, Kelly CJ, Glover LE, McNamee EN, Bowers BE, Bayless AJ, Scully M, Saeedi BJ, Golden-Mason L, Ehrentraut SF, Curtis VF, Burgess A, Garvey JF, Sorensen A, Nemenoff R, Jedlicka P, Taylor CT, Kominsky DJ, Colgan SP. PMID: 24412613; PMCID: PMC3951457.
      View in: PubMed   Mentions: 249     Fields:    Translation:AnimalsCells
    28. Class I HDACs regulate angiotensin II-dependent cardiac fibrosis via fibroblasts and circulating fibrocytes. J Mol Cell Cardiol. 2014 Feb; 67:112-25. Williams SM, Golden-Mason L, Ferguson BS, Schuetze KB, Cavasin MA, Demos-Davies K, Yeager ME, Stenmark KR, McKinsey TA. PMID: 24374140; PMCID: PMC4120952.
      View in: PubMed   Mentions: 78     Fields:    Translation:HumansAnimalsCells
    29. Natural killer cells: multifaceted players with key roles in hepatitis C immunity. Immunol Rev. 2013 Sep; 255(1):68-81. Golden-Mason L, Rosen HR. PMID: 23947348; PMCID: PMC3765000.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    30. Hepatitis C virus pathogen associated molecular pattern (PAMP) triggers production of lambda-interferons by human plasmacytoid dendritic cells. PLoS Pathog. 2013; 9(4):e1003316. Stone AE, Giugliano S, Schnell G, Cheng L, Leahy KF, Golden-Mason L, Gale M, Rosen HR. PMID: 23637605; PMCID: PMC3630164.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    31. Bile acid receptor activation modulates hepatic monocyte activity and improves nonalcoholic fatty liver disease. J Biol Chem. 2013 Apr 26; 288(17):11761-70. McMahan RH, Wang XX, Cheng LL, Krisko T, Smith M, El Kasmi K, Pruzanski M, Adorini L, Golden-Mason L, Levi M, Rosen HR. PMID: 23460643; PMCID: PMC3636865.
      View in: PubMed   Mentions: 103     Fields:    Translation:HumansAnimalsCells
    32. Galectin-9 functionally impairs natural killer cells in humans and mice. J Virol. 2013 May; 87(9):4835-45. Golden-Mason L, McMahan RH, Strong M, Reisdorph R, Mahaffey S, Palmer BE, Cheng L, Kulesza C, Hirashima M, Niki T, Rosen HR. PMID: 23408620; PMCID: PMC3624298.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimalsCells
    33. Race- and gender-related variation in natural killer p46 expression associated with differential anti-hepatitis C virus immunity. Hepatology. 2012 Oct; 56(4):1214-22. Golden-Mason L, Stone AE, Bambha KM, Cheng L, Rosen HR. PMID: 22505144; PMCID: PMC3458134.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    34. A summary of the 18th International Symposium on Hepatitis C Virus and Related Viruses. Gastroenterology. 2012 Jan; 142(1):e1-5. Polyak SJ, Morishima C, Scott JD, Gastaminza P, Cox A, de Araújo ES, Higgs MR, Loo YM, Golden-Mason L, Lindenbach BD, Baumert TF, Randall G, Gale M. PMID: 22185796.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    35. Interleukin (IL)-17/IL-22-producing T cells enriched within the liver of patients with chronic hepatitis C viral (HCV) infection. Dig Dis Sci. 2012 Feb; 57(2):381-9. Foster RG, Golden-Mason L, Rutebemberwa A, Rosen HR. PMID: 22183819.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    36. Differential expression of NK receptors CD94 and NKG2A by T cells in rheumatoid arthritis patients in remission compared to active disease. PLoS One. 2011; 6(11):e27182. Walsh CE, Ryan EJ, O'Farrelly C, Golden-Mason L, FitzGerald O, Veale DJ, Bresnihan B, Fearon U. PMID: 22102879; PMCID: PMC3216944.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    37. Natural killer inhibitory receptor expression associated with treatment failure and interleukin-28B genotype in patients with chronic hepatitis C. Hepatology. 2011 Nov; 54(5):1559-69. Golden-Mason L, Bambha KM, Cheng L, Howell CD, Taylor MW, Clark PJ, Afdhal N, Rosen HR, Virahep-C Study Group. PMID: 21983945; PMCID: PMC3206734.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    38. Hepatitis C virus targets the T cell secretory machinery as a mechanism of immune evasion. Hepatology. 2011 Jun; 53(6):1846-53. Petrovic D, Stamataki Z, Dempsey E, Golden-Mason L, Freeley M, Doherty D, Prichard D, Keogh C, Conroy J, Mitchell S, Volkov Y, McKeating JA, O'Farrelly C, Kelleher D, Long A. PMID: 21452285.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    39. Defective leukocyte GM-CSF receptor (CD116) expression and function in inflammatory bowel disease. Gastroenterology. 2011 Jul; 141(1):208-16. Goldstein JI, Kominsky DJ, Jacobson N, Bowers B, Regalia K, Austin GL, Yousefi M, Falta MT, Fontenot AP, Gerich ME, Golden-Mason L, Colgan SP. PMID: 21557945; PMCID: PMC3362207.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    40. Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity. J Clin Invest. 2010 Dec; 120(12):4546-57. McMahan RH, Golden-Mason L, Nishimura MI, McMahon BJ, Kemper M, Allen TM, Gretch DR, Rosen HR. PMID: 21084749; PMCID: PMC2994339.
      View in: PubMed   Mentions: 170     Fields:    Translation:HumansCells
    41. Increased natural killer cell cytotoxicity and NKp30 expression protects against hepatitis C virus infection in high-risk individuals and inhibits replication in vitro. Hepatology. 2010 Nov; 52(5):1581-9. Golden-Mason L, Cox AL, Randall JA, Cheng L, Rosen HR. PMID: 20812318; PMCID: PMC2967665.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
    42. Innate immune function in placenta and cord blood of hepatitis C--seropositive mother-infant dyads. PLoS One. 2010 Aug 30; 5(8):e12232. Hurtado CW, Golden-Mason L, Brocato M, Krull M, Narkewicz MR, Rosen HR. PMID: 20814429; PMCID: PMC2923602.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    43. Transduction of human T cells with a novel T-cell receptor confers anti-HCV reactivity. PLoS Pathog. 2010 Jul 29; 6(7):e1001018. Zhang Y, Liu Y, Moxley KM, Golden-Mason L, Hughes MG, Liu T, Heemskerk MH, Rosen HR, Nishimura MI. PMID: 20686664; PMCID: PMC2912399.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    44. Regulation of virus-specific CD4+ T cell function by multiple costimulatory receptors during chronic HIV infection. J Immunol. 2010 Sep 01; 185(5):3007-18. Kassu A, Marcus RA, D'Souza MB, Kelly-McKnight EA, Golden-Mason L, Akkina R, Fontenot AP, Wilson CC, Palmer BE. PMID: 20656923; PMCID: PMC3985382.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansCells
    45. A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in hepatitis C infection. PLoS One. 2010 Mar 04; 5(3):e9504. Mengshol JA, Golden-Mason L, Arikawa T, Smith M, Niki T, McWilliams R, Randall JA, McMahan R, Zimmerman MA, Rangachari M, Dobrinskikh E, Busson P, Polyak SJ, Hirashima M, Rosen HR. PMID: 20209097; PMCID: PMC2831996.
      View in: PubMed   Mentions: 111     Fields:    Translation:HumansCells
    46. Comprehensive assessment of chemokine expression profiles by flow cytometry. J Clin Invest. 2010 Mar; 120(3):907-23. Eberlein J, Nguyen TT, Victorino F, Golden-Mason L, Rosen HR, Homann D. PMID: 20197626; PMCID: PMC2827956.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    47. Negative immune regulator Tim-3 is overexpressed on T cells in hepatitis C virus infection and its blockade rescues dysfunctional CD4+ and CD8+ T cells. J Virol. 2009 Sep; 83(18):9122-30. Golden-Mason L, Palmer BE, Kassam N, Townshend-Bulson L, Livingston S, McMahon BJ, Castelblanco N, Kuchroo V, Gretch DR, Rosen HR. PMID: 19587053; PMCID: PMC2738247.
      View in: PubMed   Mentions: 254     Fields:    Translation:HumansCells
    48. Natural killer cells play divergent roles in shaping the outcome of hepatitis C virus recurrence following liver transplantation. Liver Transpl. 2009 Apr; 15(4):357-9. Golden-Mason L. PMID: 19326413.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    49. Changes in endometrial natural killer cell expression of CD94, CD158a and CD158b are associated with infertility. Am J Reprod Immunol. 2009 Apr; 61(4):265-76. McGrath E, Ryan EJ, Lynch L, Golden-Mason L, Mooney E, Eogan M, O'Herlihy C, O'Farrelly C. PMID: 19260857.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    50. Prospective analysis of effector and regulatory CD4+ T cells in chronic HCV patients undergoing combination antiviral therapy. J Hepatol. 2008 Sep; 49(3):329-38. Burton JR, Klarquist J, Im K, Smyk-Pearson S, Golden-Mason L, Castelblanco N, Terrault N, Rosen HR, Virahep-C Study Group. PMID: 18644644.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCellsCTClinical Trials
    51. Cutting edge: programmed death-1 expression is increased on immunocytes in chronic hepatitis C virus and predicts failure of response to antiviral therapy: race-dependent differences. J Immunol. 2008 Mar 15; 180(6):3637-41. Golden-Mason L, Klarquist J, Wahed AS, Rosen HR. PMID: 18322167.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansCells
    52. Functional suppression by FoxP3+CD4+CD25(high) regulatory T cells during acute hepatitis C virus infection. J Infect Dis. 2008 Jan 01; 197(1):46-57. Smyk-Pearson S, Golden-Mason L, Klarquist J, Burton JR, Tester IA, Wang CC, Culbertson N, Vandenbark AA, Rosen HR. PMID: 18171284.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    53. Pretransplantation CD56(+) innate lymphocyte populations associated with severity of hepatitis C virus recurrence. Liver Transpl. 2008 Jan; 14(1):31-40. Rosen HR, Doherty DG, Madrigal-Estebas L, O'Farrelly C, Golden-Mason L. PMID: 18161829.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    54. Spontaneous recovery in acute human hepatitis C virus infection: functional T-cell thresholds and relative importance of CD4 help. J Virol. 2008 Feb; 82(4):1827-37. Smyk-Pearson S, Tester IA, Klarquist J, Palmer BE, Pawlotsky JM, Golden-Mason L, Rosen HR. PMID: 18045940; PMCID: PMC2258714.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    55. Mechanisms of Disease: HCV-induced liver injury. Nat Clin Pract Gastroenterol Hepatol. 2007 Nov; 4(11):622-34. Mengshol JA, Golden-Mason L, Rosen HR. PMID: 17978819.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    56. Upregulation of PD-1 expression on circulating and intrahepatic hepatitis C virus-specific CD8+ T cells associated with reversible immune dysfunction. J Virol. 2007 Sep; 81(17):9249-58. Golden-Mason L, Palmer B, Klarquist J, Mengshol JA, Castelblanco N, Rosen HR. PMID: 17567698; PMCID: PMC1951397.
      View in: PubMed   Mentions: 202     Fields:    Translation:HumansCells
    57. Phenotypic and functional changes of cytotoxic CD56pos natural T cells determine outcome of acute hepatitis C virus infection. J Virol. 2007 Sep; 81(17):9292-8. Golden-Mason L, Castelblanco N, O'Farrelly C, Rosen HR. PMID: 17553896; PMCID: PMC1951454.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    58. Loss of IL-7 receptor alpha-chain (CD127) expression in acute HCV infection associated with viral persistence. Hepatology. 2006 Nov; 44(5):1098-109. Golden-Mason L, Burton JR, Castelblanco N, Klarquist J, Benlloch S, Wang C, Rosen HR. PMID: 17058243.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansCells
    59. Changes in hepatic immunoregulatory cytokines in patients with metastatic colorectal carcinoma: implications for hepatic anti-tumour immunity. Cytokine. 2006 Aug; 35(3-4):171-9. Kelly AM, Golden-Mason L, Traynor O, Geoghegan J, McEntee G, Hegarty JE, O'Farrelly C. PMID: 16971136.
      View in: PubMed   Mentions: 13  Translation:Humans
    60. Detection and characterization of hemopoietic stem cells in the adult human small intestine. J Immunol. 2006 May 01; 176(9):5199-204. Lynch L, O'Donoghue D, Dean J, O'Sullivan J, O'Farrelly C, Golden-Mason L. PMID: 16621984.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    61. Resolution of endothelial activation and down-regulation of Tie2 receptor in psoriatic skin after infliximab therapy. J Am Acad Dermatol. 2006 Jun; 54(6):1003-12. Markham T, Mullan R, Golden-Mason L, Rogers S, Bresnihan B, Fitzgerald O, Fearon U, Veale DJ. PMID: 16713454.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    62. Natural killer cells: primary target for hepatitis C virus immune evasion strategies? Liver Transpl. 2006 Mar; 12(3):363-72. Golden-Mason L, Rosen HR. PMID: 16498647.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    63. The hepatitis C envelope 2 protein inhibits LFA-1-transduced protein kinase C signaling for T-lymphocyte migration. Gastroenterology. 2006 Feb; 130(2):482-92. Volkov Y, Long A, Freeley M, Golden-Mason L, O'Farrelly C, Murphy A, Kelleher D. PMID: 16472601.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    64. Acute-phase serum amyloid A stimulation of angiogenesis, leukocyte recruitment, and matrix degradation in rheumatoid arthritis through an NF-kappaB-dependent signal transduction pathway. Arthritis Rheum. 2006 Jan; 54(1):105-14. Mullan RH, Bresnihan B, Golden-Mason L, Markham T, O'Hara R, FitzGerald O, Veale DJ, Fearon U. PMID: 16385502.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    65. Trephine biopsies are enriched for activated T/NK cells and cytotoxic T cells. Immunol Lett. 2005 Jun 15; 99(1):94-102. Dean J, McCarthy D, Golden-Mason L, O'farrelly C. PMID: 15894117.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    66. Distinct subpopulations of gamma delta T cells are present in normal and tumor-bearing human liver. Clin Immunol. 2004 Oct; 113(1):56-63. Kenna T, Golden-Mason L, Norris S, Hegarty JE, O'Farrelly C, Doherty DG. PMID: 15380530.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
    67. Nitric oxide in early ischaemia reperfusion injury during human orthotopic liver transplantation. Transplantation. 2004 Jul 27; 78(2):250-6. Varadarajan R, Golden-Mason L, Young L, McLoughlin P, Nolan N, McEntee G, Traynor O, Geoghegan J, Hegarty JE, O'Farrelly C. PMID: 15280686.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    68. Adult human liver contains CD8pos T cells with naive phenotype, but is not a site for conventional alpha beta T cell development. J Immunol. 2004 May 15; 172(10):5980-5. Golden-Mason L, Douek DC, Koup RA, Kelly J, Hegarty JE, O'Farrelly C. PMID: 15128780.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    69. Cortisol does not mediate the suppressive effects of psychiatric morbidity on natural killer cell activity: a cross-sectional study of patients with early breast cancer. Psychol Med. 2004 Apr; 34(3):481-90. Garland MR, Lavelle E, Doherty D, Golden-Mason L, Fitzpatrick P, Hill A, Walsh N, O'Farrelly C. PMID: 15259833.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    70. Interleukin 12 (IL-12) is increased in tumour bearing human liver and expands CD8(+) and CD56(+) T cells in vitro but not in vivo. Cytokine. 2004 Mar 21; 25(6):273-82. Kelly AM, Golden-Mason L, McEntee G, Traynor O, Doherty DG, Hegarty JE, O'Farrelly C. PMID: 15036243.
      View in: PubMed   Mentions: 3  Translation:HumansCells
    71. Localization of T and B lymphocytes in histologically normal adult human donor liver. Hepatogastroenterology. 2003 Sep-Oct; 50(53):1311-5. Smith F, Golden-Mason L, Deignan T, Norris S, Nolan N, Traynor O, McEntee G, Hegarty J, O'Farrelly C. PMID: 14571725.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    72. NKT cells from normal and tumor-bearing human livers are phenotypically and functionally distinct from murine NKT cells. J Immunol. 2003 Aug 15; 171(4):1775-9. Kenna T, Golden-Mason L, Porcelli SA, Koezuka Y, Hegarty JE, O'Farrelly C, Doherty DG, Mason LG. PMID: 12902477.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansAnimalsCells
    73. Stress-related hormonal suppression of natural killer activity does not show menstrual cycle variations: implications for timing of surgery for breast cancer. Anticancer Res. 2003 May-Jun; 23(3B):2531-5. Garland M, Doherty D, Golden-Mason L, Fitzpatrick P, Walsh N, O'Farrelly C. PMID: 12894537.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    74. Expansion of innate CD5pos B cells expressing high levels of CD81 in hepatitis C virus infected liver. J Hepatol. 2003 May; 38(5):642-50. Curry MP, Golden-Mason L, Doherty DG, Deignan T, Norris S, Duffy M, Nolan N, Hall W, Hegarty JE, O'Farrelly C. PMID: 12713876.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    75. Decrease in hepatic CD56(+) T cells and V alpha 24(+) natural killer T cells in chronic hepatitis C viral infection. J Hepatol. 2002 Jul; 37(1):101-8. Deignan T, Curry MP, Doherty DG, Golden-Mason L, Volkov Y, Norris S, Nolan N, Traynor O, McEntee G, Hegarty JE, O'Farrelly C. PMID: 12076868.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    76. Having it all? Stem cells, haematopoiesis and lymphopoiesis in adult human liver. Immunol Cell Biol. 2002 Feb; 80(1):45-51. Golden-Mason L, O'Farrelly C. PMID: 11869362.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
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