Ana Claudia Maretti Garcia, PhD

Title(s)Assistant Professor of Research Medicine
SchoolKeck School of Medicine of Usc
Address1450 Biggy St.
Health Sciences Campus
Los Angeles CA 90033
Phone+1 323 865 1240
ORCID ORCID Icon0000-0002-6252-2811 Additional info
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    Collapse Biography 
    Collapse Education and Training
    Universidade Federal do Rio de Janeiro, BrazilBS2004Biomedical Sciences
    FIOCRUZ, BrazilMS2006Parasitology
    FIOCRUZ, BrazilPhD2011Molecular and Cellular Biology
    University of California, Los Angeles, Los Angeles2013Post-doctoral, Immunology
    Cedars-Sinai, Los Angeles2014Post-doctoral, Molecular Immunology
    University of Southern California, Los Angeles2018Post-doctoral, Liver Biology
    University of Southern California, Los Angeles2021Post-doctoral, Liver Immunology
    Collapse Awards and Honors
    NIH2017  - 2018RCLD Young Investigator Award
    American Association for the Study of Liver Diseases2016Presidential Poster of Distinction
    American Association for the Study of Liver Diseases2016Basic Science Young Investigator Travel Award
    Brazilian Society of Protozoology2007Best Scientific Presentation Award

    Collapse Overview 
    Collapse Overview
    Dr. Maretti-Garcia earned her B.S. degree in biomedical sciences, M.S. in Parasitology, and Ph.D. in Molecular and Cellular Biology in Brazil. After completing her postdoctoral training at the University of California, Los Angeles (UCLA), where she studied the immunopathology of tropical diseases, she joined the University of Southern California (USC) to study liver diseases.

    Recently, Dr. Maretti-Garcia became an Assistant Professor at Keck School of Medicine of USC, and her research interest mainly concentrates on the contribution of the immune response to the progression of chronic liver diseases. She is an expert in cutting-edge technologies used for transcriptomic analyses and for real-time cellular behavior assays.
    Collapse Websites

    Collapse Research 
    Collapse Research Activities and Funding
    Maturation of engrafted bone marrow Sinusoidal endothelial cell PROgenitor Cells (sprocs)
    NIH Jan 1, 2017 - Dec 31, 2018
    Role: Principal Investigator
    Description: Awarded by Research Center for Liver Disease to junior investigators to foster a career development in liver research.

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Chronic HCV infection promotes cytotoxicity in antigen-specific CD8+ T cells regardless of virus specificity. Frontiers in Virology. 2023; 3. Maretti-Mira Ana C., Salomon Matthew P., Hsu Angela M., Matsuba Chikako, Golden-Mason Lucy. View Publication.
    2. Editorial: New strategies for the treatment of diseases caused by trypanosomatid parasites. Front. Cell. Infect. Microbiol. 2023; 13. Cardoso Flávia de Oliveira, Almeida-Souza Fernando, Maretti-Mira Ana Cláudia, Abreu-Silva Ana Lúcia. View Publication.
    3. Etiology of end-stage liver cirrhosis impacts hepatic natural killer cell heterogenicity. Front Immunol. 2023; 14:1137034. Ana C Maretti-Mira, Matthew P Salomon, Angela M Hsu, Lily Dara, Lucy Golden-Mason. View Publication.
    4. Hepatic damage caused by long-term high cholesterol intake induces a dysfunctional restorative macrophage population in experimental NASH. Front Immunol. 2022; 13:968366. Ana C Maretti-Mira, Matthew P Salomon, Angela M Hsu, Gary C Kanel, Lucy Golden-Mason. View Publication.
    5. Single-cell transcriptomic analyses of T cells in chronic HCV-infected patients dominated by DAA-induced interferon signaling changes. PLoS Pathog. 2021 08; 17(8):e1009799. Burchill MA, Salomon MP, Golden-Mason L, Wieland A, Maretti-Mira AC, Gale M, Rosen HR. PMID: 34370798; PMCID: PMC8376199.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    6. Cholesterol-Induced M4-Like Macrophages Recruit Neutrophils and Induce NETosis. Front Immunol. 2021; 12:671073. Maretti-Mira AC, Golden-Mason L, Salomon MP, Kaplan MJ, Rosen HR. PMID: 34012454; PMCID: PMC8126646.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    7. Susceptibility of Rat Steatotic Liver to Ischemia-Reperfusion Is Treatable With Liver-Selective Matrix Metalloproteinase Inhibition. Hepatology. 2020 11; 72(5):1771-1785. Wang X, Walkey CJ, Maretti-Mira AC, Wang L, Johnson DL, DeLeve LD. PMID: 32060938; PMCID: PMC7523533.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    8. Sinusoids as Drivers of Liver Development: More Than Simple Chemistry. Hepatology. 2019 08; 70(2):737-739. Maretti-Mira AC, DeLeve LD. PMID: 30681732.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    9. Incomplete Differentiation of Engrafted Bone Marrow Endothelial Progenitor Cells Initiates Hepatic Fibrosis in the Rat. Hepatology. 2019 03; 69(3):1259-1272. Maretti-Mira AC, Wang X, Wang L, DeLeve LD. PMID: 30141211; PMCID: PMC6387651.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    10. Liver-Selective MMP-9 Inhibition in the Rat Eliminates Ischemia-Reperfusion Injury and Accelerates Liver Regeneration. Hepatology. 2019 01; 69(1):314-328. Wang X, Maretti-Mira AC, Wang L, DeLeve LD. PMID: 30019419; PMCID: PMC6325019.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    11. Liver Sinusoidal Endothelial Cell: An Update. Semin Liver Dis. 2017 11; 37(4):377-387. DeLeve LD, Maretti-Mira AC. PMID: 29272898; PMCID: PMC6005648.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimalsCells
    12. Severity of tegumentary leishmaniasis is not exclusively associated with Leishmania RNA virus 1 infection in Brazil. Mem Inst Oswaldo Cruz. 2013 Aug; 108(5):665-7. Pereira Lde O, Maretti-Mira AC, Rodrigues KM, Lima RB, Oliveira-Neto MP, Cupolillo E, Pirmez C, de Oliveira MP. PMID: 23903986; PMCID: PMC3970596.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    13. Transcriptome patterns from primary cutaneous Leishmania braziliensis infections associate with eventual development of mucosal disease in humans. PLoS Negl Trop Dis. 2012; 6(9):e1816. Maretti-Mira AC, Bittner J, Oliveira-Neto MP, Liu M, Kang D, Li H, Pirmez C, Craft N. PMID: 23029578; PMCID: PMC3441406.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    14. Efficacy of synthetic peptides RP-1 and AA-RP-1 against Leishmania species in vitro and in vivo. Antimicrob Agents Chemother. 2012 Feb; 56(2):658-65. Erfe MC, David CV, Huang C, Lu V, Maretti-Mira AC, Haskell J, Bruhn KW, Yeaman MR, Craft N. PMID: 22123683; PMCID: PMC3264259.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    15. MMP-9 activity is induced by Leishmania braziliensis infection and correlates with mucosal leishmaniasis. Acta Trop. 2011 Aug; 119(2-3):160-4. Maretti-Mira AC, de Pinho Rodrigues KM, de Oliveira-Neto MP, Pirmez C, Craft N. PMID: 21663729.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    16. Influence of the Notch system in the therapeutic response of American tegumentary leishmaniasis. Br J Dermatol. 2011 Jun; 164(6):1228-34. Rodrigues KM, Oliveira MP, Maretti-Mira AC, Oliveira-Neto MP, Mattos MS, Silva L, Soares DA, Dolci EL, Perico RA, Pirmez C. PMID: 21299543.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    17. Therapeutic failure in American cutaneous leishmaniasis is associated with gelatinase activity and cytokine expression. Clin Exp Immunol. 2011 Feb; 163(2):207-14. Maretti-Mira AC, de Oliveira-Neto MP, Da-Cruz AM, de Oliveira MP, Craft N, Pirmez C. PMID: 21091666; PMCID: PMC3043311.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    18. LXR deficiency confers increased protection against visceral Leishmania infection in mice. PLoS Negl Trop Dis. 2010 Nov 16; 4(11):e886. Bruhn KW, Marathe C, Maretti-Mira AC, Nguyen H, Haskell J, Tran TA, Vanchinathan V, Gaur U, Wilson ME, Tontonoz P, Craft N. PMID: 21103366; PMCID: PMC2982826.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
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