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Qifa Zhou, PhD

Title(s)Approval Routing - Faculty Manager
AddressMMR 312 1333 San Pablo Street
University Park Campus
Los Angeles CA 90033-6103
Phone+1 213 740 9475
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    Dr. Zhou’s research focuses on the design and fabrication of high frequency ultrasonic transducers using new piezoelectric single crystal and thin film technologies for medical imaging applications. He has integrated ultrasonic technology with advanced optical technology for intravascular imaging application. His current work is to develop miniaturized photoacoustic imaging (PA) probes using high frequency ultrasound transducers for endoscopic application. The primary motivations are to overcome the depth limitation of existing endoscopic imaging technologies and to provide functional information for disease states via photoacoustic imaging.

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    Non-invasive Ultrasound Stimulated Retinal Prosthesis
    NIH/NEI R01EY030126Apr 1, 2019 - Mar 31, 2023
    Role: Principal Investigator
    High-resolution Elastographic Assessment of the Optic Nerve Head
    NIH/NEI R01EY028662Apr 1, 2018 - Mar 31, 2022
    Role: Principal Investigator
    Large aperture and wideband modular ultrasound arrays for the diagnosis of liver cancer
    NIH/NCI R01CA211602Mar 8, 2017 - Feb 28, 2022
    Role: Co-Principal Investigator
    High Resolution Elastograpy of Retina Under Prosthetic Electrical Stimulation
    NIH/NEI R01EY026091Dec 1, 2015 - Nov 30, 2019
    Role: Principal Investigator
    Combined OCT/US/PAT system for intravascular Imaging
    NIH/NHLBI R01HL127271Apr 1, 2015 - Mar 31, 2019
    Role: Co-Principal Investigator
    Phase resolved ARF optical coherence elastography for intravascular imaging
    NIH/NHLBI R01HL125084Aug 15, 2014 - Apr 30, 2018
    Role: Co-Principal Investigator
    Elastographic Imaging of the Retina/Choroid in Age-Related Macular Degeneration
    NIH/NEI R01EY021529Feb 1, 2012 - Jan 31, 2016
    Role: Co-Principal Investigator
    Photoacoustic endoscopy of Barretts esophagus
    NIH/NCI R01CA157277Sep 1, 2010 - Jun 30, 2015
    Role: Co-Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A combined ultrasonic B-mode and color Doppler system for the classification of breast masses using neural network. Eur Radiol. 2020 May; 30(5):3023-3033. Qian X, Zhang B, Liu S, Wang Y, Chen X, Liu J, Yang Y, Chen X, Wei Y, Xiao Q, Ma J, Shung KK, Zhou Q, Liu L, Chen Z. PMID: 32006174.
      View in: PubMed   Mentions:    Fields:    
    2. In vivo evaluation of posterior eye elasticity using shaker-based optical coherence elastography. Exp Biol Med (Maywood). 2020 Feb; 245(4):282-288. Qian X, Li R, Li Y, Lu G, He Y, Humayun MS, Chen Z, Zhou Q. PMID: 31910651.
      View in: PubMed   Mentions:    Fields:    
    3. Editorial for the Special Issue on MEMS Technology for Biomedical Imaging Applications. Micromachines (Basel). 2019 Sep 16; 10(9). Zhou Q, Zhang Y. PMID: 31527420.
      View in: PubMed   Mentions:
    4. Electrically assisted 3D printing of nacre-inspired structures with self-sensing capability. Sci Adv. 2019 Apr; 5(4):eaau9490. Yang Y, Li X, Chu M, Sun H, Jin J, Yu K, Wang Q, Zhou Q, Chen Y. PMID: 30972361.
      View in: PubMed   Mentions:    Fields:    
    5. Three-Dimensional Printed Piezoelectric Array for Improving Acoustic Field and Spatial Resolution in Medical Ultrasonic Imaging. Micromachines (Basel). 2019 Feb 28; 10(3). Chen Z, Qian X, Song X, Jiang Q, Huang R, Yang Y, Li R, Shung K, Chen Y, Zhou Q. PMID: 30823480.
      View in: PubMed   Mentions:
    6. Flexible piezoelectric ultrasonic energy harvester array for bio-implantable wireless generator. Nano Energy. 2019 Feb; 56:216-224. Jiang L, Yang Y, Chen R, Lu G, Li R, Li D, Humayun MS, Shung KK, Zhu J, Chen Y, Zhou Q. PMID: 31475091.
      View in: PubMed   Mentions:
    7. High-Speed Integrated Endoscopic Photoacoustic and Ultrasound Imaging System. IEEE J Sel Top Quantum Electron. 2019 Jan-Feb; 25(1). Li Y, Zhu Z, Jing JC, Chen JJ, Heidari E, He Y, Zhu J, Ma T, Yu M, Zhou Q, Chen Z. PMID: 31447542.
      View in: PubMed   Mentions:
    8. Novel Configurations of Ultrahigh Frequency (=600 MHz) Analog Frontend for High Resolution Ultrasound Measurement. Sensors (Basel). 2018 Aug 08; 18(8). Kim MG, Park J, Zhou Q, Shung KK. PMID: 30096810.
      View in: PubMed   Mentions:    Fields:    
    9. Recent Progress in Biomimetic Additive Manufacturing Technology: From Materials to Functional Structures. Adv Mater. 2018 Jun 19; e1706539. Yang Y, Song X, Li X, Chen Z, Zhou C, Zhou Q, Chen Y. PMID: 29920790.
      View in: PubMed   Mentions: 2     Fields:    
    10. 3D-Printed Biomimetic Super-Hydrophobic Structure for Microdroplet Manipulation and Oil/Water Separation. Adv Mater. 2018 Mar; 30(9). Yang Y, Li X, Zheng X, Chen Z, Zhou Q, Chen Y. PMID: 29280219.
      View in: PubMed   Mentions: 3     Fields:    
    11. Functional Assay of Cancer Cell Invasion Potential Based on Mechanotransduction of Focused Ultrasound. Front Oncol. 2017; 7:161. Weitz AC, Lee NS, Yoon CW, Bonyad A, Goo KS, Kim S, Moon S, Jung H, Zhou Q, Chow RH, Shung KK. PMID: 28824873.
      View in: PubMed   Mentions:
    12. Multi-functional Ultrasonic Micro-elastography Imaging System. Sci Rep. 2017 04 27; 7(1):1230. Qian X, Ma T, Yu M, Chen X, Shung KK, Zhou Q. PMID: 28450709.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    13. High-Frequency Ultrasonic Imaging with Lead-free (Na,K)(Nb,Ta)O3 Single Crystal. Ultrason Imaging. 2017 11; 39(6):348-356. Chen Z, Zheng L, Cao W, Chen X, Chen R, Li R, Shung K, Zhou Q. PMID: 28395599.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    14. Biomimetic Anisotropic Reinforcement Architectures by Electrically Assisted Nanocomposite 3D Printing. Adv Mater. 2017 Mar; 29(11). Yang Y, Chen Z, Song X, Zhang Z, Zhang J, Shung KK, Zhou Q, Chen Y. PMID: 28185341.
      View in: PubMed   Mentions: 4     Fields:    
    15. High-resolution harmonic motion imaging (HR-HMI) for tissue biomechanical property characterization. Quant Imaging Med Surg. 2015 Feb; 5(1):108-17. Ma T, Qian X, Chiu CT, Yu M, Jung H, Tung YS, Shung KK, Zhou Q. PMID: 25694960.
      View in: PubMed   Mentions:
    16. A feasibility study of in vivo applications of single beam acoustic tweezers. Appl Phys Lett. 2014 Oct 27; 105(17):173701. Li Y, Lee C, Chen R, Zhou Q, Shung KK. PMID: 25422525.
      View in: PubMed   Mentions:
    17. Piezoelectric single crystals for ultrasonic transducers in biomedical applications. Prog Mater Sci. 2014 Oct 01; 66:87-111. Zhou Q, Lam KH, Zheng H, Qiu W, Shung KK. PMID: 25386032.
      View in: PubMed   Mentions:
    18. Integrated IVUS-OCT Imaging for Atherosclerotic Plaque Characterization. IEEE J Sel Top Quantum Electron. 2014 Mar; 20(2):7100108. Li X, Li J, Jing J, Ma T, Liang S, Zhang J, Mohar D, Raney A, Mahon S, Brenner M, Patel P, Shung KK, Zhou Q, Chen Z. PMID: 24771992.
      View in: PubMed   Mentions:
    19. Systematic study of high-frequency ultrasonic transducer design for laser-scanning photoacoustic ophthalmoscopy. J Biomed Opt. 2014 Jan; 19(1):16015. Ma T, Zhang X, Chiu CT, Chen R, Kirk Shung K, Zhou Q, Jiao S. PMID: 24441942.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    20. High frequency photoacoustic imaging for in vivo visualizing blood flow of zebrafish heart. Opt Express. 2013 Jun 17; 21(12):14636-42. Park J, Cummins TM, Harrison M, Lee J, Zhou Q, Lien CL, Shung KK. PMID: 23787651.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    21. Silver Doped 0.9PMN-PT-0.1PZT Composite Films for very High Frequency Ultrasonic Transducer Applications. Appl Phys A Mater Sci Process. 2013 May 01; 111(2):459-463. Hsu HS, Benjauthrit V, Wei Q, Huang Y, Zhou Q, Shung KK. PMID: 23814408.
      View in: PubMed   Mentions:
    22. Investigating contactless high frequency ultrasound microbeam stimulation for determination of invasion potential of breast cancer cells. Biotechnol Bioeng. 2013 Oct; 110(10):2697-705. Hwang JY, Lee NS, Lee C, Lam KH, Kim HH, Woo J, Lin MY, Kisler K, Choi H, Zhou Q, Chow RH, Shung KK. PMID: 23568761.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    23. Development of lead-free single-element ultrahigh frequency (170-320MHz) ultrasonic transducers. Ultrasonics. 2013 Jul; 53(5):1033-8. Lam KH, Ji HF, Zheng F, Ren W, Zhou Q, Shung KK. PMID: 23485349.
      View in: PubMed   Mentions: 2     Fields:    
    24. In vivo Sonothrombolysis of Ear Marginal Vein of Rabbits Monitored with High-frequency Ultrasound Needle Transducer. J Med Biol Eng. 2013; 33(1):103-110. Chen R, Paeng DG, Lam KH, Zhou Q, Shung KK, Matsuoka N, Humayun MS. PMID: 25356073.
      View in: PubMed   Mentions:
    25. Elevated electrochemical impedance in the endoluminal regions with high shear stress: implication for assessing lipid-rich atherosclerotic lesions. Biosens Bioelectron. 2013 May 15; 43:237-44. Yu F, Lee J, Jen N, Li X, Zhang Q, Tang R, Zhou Q, Kim ES, Hsiai TK. PMID: 23318546.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    26. Thermal-independent properties of PIN-PMN-PT single-crystal linear-array ultrasonic transducers. IEEE Trans Ultrason Ferroelectr Freq Control. 2012 Dec; 59(12):2777-84. Chen R, Wu J, Ho Lam K, Yao L, Zhou Q, Tian J, Han P, Shung KK. PMID: 23221227.
      View in: PubMed   Mentions: 5     Fields:    
    27. Ultrahigh frequency lensless ultrasonic transducers for acoustic tweezers application. Biotechnol Bioeng. 2013 Mar; 110(3):881-6. Lam KH, Hsu HS, Li Y, Lee C, Lin A, Zhou Q, Kim ES, Shung KK. PMID: 23042219.
      View in: PubMed   Mentions: 22     Fields:    
    28. 20 MHz forward-imaging single-element beam steering with an internal rotating variable-angle reflecting surface: Wire phantom and ex vivo pilot study. Ultrasonics. 2013 Feb; 53(2):561-9. Raphael DT, Li X, Park J, Chen R, Chabok H, Barukh A, Zhou Q, Elgazery M, Shung KK. PMID: 23122968.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    29. Intravascular photoacoustic imaging at 35 and 80 MHz. J Biomed Opt. 2012 Oct; 17(10):106005. Li X, Wei W, Zhou Q, Shung KK, Chen Z. PMID: 23224004.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    30. Pulse inversion chirp coded tissue harmonic imaging (PI-CTHI) of Zebrafish heart using high frame rate ultrasound biomicroscopy. Ann Biomed Eng. 2013 Jan; 41(1):41-52. Park J, Huang Y, Chen R, Lee J, Cummins TM, Zhou Q, Lien CL, Shung KK. PMID: 22930467.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    31. Combined chirp coded tissue harmonic and fundamental ultrasound imaging for intravascular ultrasound: 20-60 MHz phantom and ex vivo results. Ultrasonics. 2013 Feb; 53(2):369-76. Park J, Li X, Zhou Q, Shung KK. PMID: 22871273.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    32. PMN-PT-PZT composite films for high frequency ultrasonic transducer applications. Sens Actuators A Phys. 2012 Jun; 179:121-124. Hsu HS, Benjauthrit V, Zheng F, Chen R, Huang Y, Zhou Q, Shung KK. PMID: 23750072.
      View in: PubMed   Mentions:
    33. Development of integrated preamplifier for high-frequency ultrasonic transducers and low-power handheld receiver. IEEE Trans Ultrason Ferroelectr Freq Control. 2011 Dec; 58(12):2646-58. Choi H, Li X, Lau ST, Hu C, Zhou Q, Shung KK. PMID: 23443700.
      View in: PubMed   Mentions: 7     Fields:    
    34. 80-MHz intravascular ultrasound transducer using PMN-PT free-standing film. IEEE Trans Ultrason Ferroelectr Freq Control. 2011 Nov; 58(11):2281-8. Li X, Wu W, Chung Y, Shih WY, Shih WH, Zhou Q, Shung KK. PMID: 22083761.
      View in: PubMed   Mentions: 16     Fields:    
    35. Structure and electrical properties of (111)-oriented Pb(Mg1/3Nb2/3)O3-PbZrO3-PbTiO3 thin film for ultra-high-frequency transducer applications. IEEE Trans Ultrason Ferroelectr Freq Control. 2011 Sep; 58(9):1962-7. Zhu BP, Guo WK, Shen GZ, Zhou Q, Shung KK. PMID: 21937332.
      View in: PubMed   Mentions: 1     Fields:    
    36. Piezoelectric films for high frequency ultrasonic transducers in biomedical applications. Prog Mater Sci. 2011 Feb; 56(2):139-174. Zhou Q, Lau S, Wu D, Shung KK. PMID: 21720451.
      View in: PubMed   Mentions:
    37. Thickness Dependent Characteristics of High Permittivity PMN-0.32PT Single Crystal for High Frequency Medical Imaging Applications. Ferroelectrics. 2011; 422(1):70-76. Chabok HR, Zhou Q, Alagha S, Tian J, Han P, Shung KK. PMID: 22162876.
      View in: PubMed   Mentions:
    38. Micro-machined high-frequency (80 MHz) PZT thick film linear arrays. IEEE Trans Ultrason Ferroelectr Freq Control. 2010 Oct; 57(10):2213-20. Zhou Q, Wu D, Liu C, Zhu B, Djuth F, Shung K. PMID: 20889407.
      View in: PubMed   Mentions: 5     Fields:    
    39. Photoacoustic ophthalmoscopy for in vivo retinal imaging. Opt Express. 2010 Feb 15; 18(4):3967-72. Jiao S, Jiang M, Hu J, Fawzi A, Zhou Q, Shung KK, Puliafito CA, Zhang HF. PMID: 20389409.
      View in: PubMed   Mentions: 73     Fields:    Translation:Humans
    40. Very high frequency (beyond 100 MHz) PZT kerfless linear arrays. IEEE Trans Ultrason Ferroelectr Freq Control. 2009 Oct; 56(10):2304-10. Wu DW, Zhou Q, Geng X, Liu CG, Djuth F, Shung KK. PMID: 19942516.
      View in: PubMed   Mentions: 6     Fields:    
    41. Dielectric and Piezoelectric Properties of PZT Composite Thick Films with Variable Solution to Powder Ratios. J Am Ceram Soc. 2009 May 08; 92(6):1276-1279. Wu D, Zhou Q, Shung KK, Bharadwaja SN, Zhang D, Zheng H. PMID: 20376196.
      View in: PubMed   Mentions:
    42. Micro-electrocardiograms to study post-ventricular amputation of zebrafish heart. Ann Biomed Eng. 2009 May; 37(5):890-901. Sun P, Zhang Y, Yu F, Parks E, Lyman A, Wu Q, Ai L, Hu CH, Zhou Q, Shung K, Lien CL, Hsiai TK. PMID: 19280341.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    43. Alumina/epoxy nanocomposite matching layers for high-frequency ultrasound transducer application. IEEE Trans Ultrason Ferroelectr Freq Control. 2009 Jan; 56(1):213-9. Zhou Q, Cha JH, Huang Y, Zhang R, Cao W, Shung KK. PMID: 19213648.
      View in: PubMed   Mentions: 3     Fields:    
    44. Determining the acoustic properties of the lens using a high-frequency ultrasonic needle transducer. Ultrasound Med Biol. 2007 Dec; 33(12):1971-7. Huang CC, Zhou Q, Ameri H, Wu DW, Sun L, Wang SH, Humayun MS, Shung KK. PMID: 17673358.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    45. PMN-PT single crystal, high-frequency ultrasonic needle transducers for pulsed-wave Doppler application. IEEE Trans Ultrason Ferroelectr Freq Control. 2007 Mar; 54(3):668-75. Zhou Q, Xu X, Gottlieb EJ, Sun L, Cannata JM, Ameri H, Humayun MS, Han P, Shung KK. PMID: 17375836.
      View in: PubMed   Mentions: 44     Fields:    
    46. Coded excitation using biphase-coded pulse with mismatched filters for high-frequency ultrasound imaging. Ultrasonics. 2006 Jul; 44(3):330-6. Hu CH, Liu R, Zhou Q, Yen J, Kirk Shung K. PMID: 16714042.
      View in: PubMed   Mentions: 5     Fields:    
    47. Development of a 35-MHz piezo-composite ultrasound array for medical imaging. IEEE Trans Ultrason Ferroelectr Freq Control. 2006 Jan; 53(1):224-36. Cannata JM, Williams JA, Zhou Q, Ritter TA, Shung KK. PMID: 16471449.
      View in: PubMed   Mentions: 44     Fields:    
    48. Design and fabrication of broadband graded ultrasonic transducers with rectangular kerfs. IEEE Trans Ultrason Ferroelectr Freq Control. 2005 Nov; 52(11):2096-102. Guo H, Cannata JM, Zhou Q, Shung KK. PMID: 16422423.
      View in: PubMed   Mentions: 1     Fields:    
    49. Fabrication and characterization of micromachined high-frequency tonpilz transducers derived by PZT thick films. IEEE Trans Ultrason Ferroelectr Freq Control. 2005 Mar; 52(3):350-7. Zhou Q, Cannata JM, Meyer RJ, van Tol DJ, Tadigadapa S, Hughes WJ, Shung KK, Trolier-McKinstry S. PMID: 15857042.
      View in: PubMed   Mentions: 4     Fields:    
    50. An analytical model of multilayer ultrasonic transducers with an inversion layer. IEEE Trans Ultrason Ferroelectr Freq Control. 2005 Mar; 52(3):469-79. Huang C, Marmarelis VZ, Zhou Q, Shung KK. PMID: 15857055.
      View in: PubMed   Mentions:    Fields:    
    51. Half-thickness inversion layer high-frequency ultrasonic transducers using LiNbO3 single crystal. IEEE Trans Ultrason Ferroelectr Freq Control. 2005 Jan; 52(1):127-33. Zhou Q, Cannata JM, Guo H, Huang C, Marmarelis VZ, Shung KK. PMID: 15742569.
      View in: PubMed   Mentions: 3     Fields:    
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