Hossein Ameri, MD, PhD

Title(s)Associate Professor of Clinical Ophthalmology
SchoolKeck School of Medicine of Usc
AddressHC4 4900 1450 San Pablo Street
Health Sciences Campus
Los Angeles CA 90033-6103
Phone+1 323 865 6825
ORCID ORCID Icon0000-0002-5270-2800 Additional info
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    Other Positions
    Title(s)Director of USC Retinal Degeneration Center

    Collapse Biography 
    Collapse Education and Training
    Tehran University of Medical ScienceMD1993
    Royal College of SurgeonsFRCSI2000
    Royal College of OphthalmologistsMRCOphth2000
    University of Texas Medical BranchOphthalmology Residency2012
    University of Texas Medical BranchPhD2013
    USC Roski Eye InstituteVitreoretinal Surgery Fellowship2015
    Collapse Awards and Honors
    Department of Ophthalmology, University of Southern California2007Basic Science Award
    Association for Research in Vision and Ophthalmology2007International Travel Grant Award
    Department of Ophthalmology and Visual Sciences, University of Texas Medical Branch2010Residency Academic Achievement Award
    Department of Ophthalmology and Visual Sciences, University of Texas Medical Branch2011Academic Achievement Award
    Heed Ophthalmic Foundation2011Heed Residents Retreat
    Department of Ophthalmology and Visual Sciences, University of Texas Medical Branch2012Senior Resident Teaching Award: Outstanding Commitment to Educating Junior Colleagues with Clinical
    Department of Ophthalmology and Visual Sciences, University of Texas Medical Branch2012Leadership Award in Recognition of Exemplary Performance as a Resident Leader
    Department of Ophthalmology and Visual Sciences, University of Texas Medical Branch2012Academic Achievement Award in Recognition of Exceptional Academic Performance

    Collapse Overview 
    Collapse Overview
    Dr. Hossein Ameri graduated from Tehran University of Medical Sciences and then served as a physician and managing director of Nahavand Health Network in Iran. He received his ophthalmology and vitreoretinal surgery training in Ireland, where he was also an official lecturer at University College Cork and was a founding member of the Irish Retinal Prosthesis Group. Dr. Ameri then moved to Los Angeles for a research fellowship and became an Assistant Professor of Research Ophthalmology at the Doheny Eye Institute of the University of Southern California. He was involved in preclinical studies of Argus II and the development of wide-field retinal prostheses. In addition, he produced quality research on retinal vascular disease, retinal angiogenesis, and ocular ultrasound.

    Dr. Ameri completed his internship in general surgery at Cedars-Sinai Medical Center in Los Angeles and moved to Texas for his ophthalmology residency, during which he simultaneously earned a Ph.D. in neuroscience at the Graduate School of Biomedical Engineering of the University of Texas Medical Branch. Dr. Ameri obtained additional fellowship training in vitreoretinal surgery at USC Roski Eye Institute. An accomplished researcher and scholar, he has numerous peer-reviewed publications, holds a number of U.S. patents, and serves on the editorial board of journals. Currently, his lab is focused on developing gene therapy for acquired and inherited retinal diseases such as age-related macular degeneration, diabetic retinopathy, retinal vein occlusion, and retinitis pigmentosa.
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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Mycobacterium dormancy and antibiotic tolerance within the retinal pigment epithelium of ocular tuberculosis. bioRxiv. 2024 Mar 19. Liu R, Dang JN, Lee R, Lee JJ, Kesavamoorthy N, Ameri H, Rao N, Eoh H. PMID: 38562751; PMCID: PMC10983995.
      View in: PubMed   Mentions:
    2. Retinal Cell Biology in Health and Disease. Cells. 2024 Feb 06; 13(4). Ameri H. PMID: 38391910; PMCID: PMC10887162.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    3. Comparison of Retinal Metabolic Activity and Structural Development between rd10 Mice and Normal Mice Using Multiphoton Fluorescence Lifetime Imaging Microscopy. Curr Issues Mol Biol. 2024 Jan 06; 46(1):612-620. Su E, Kesavamoorthy N, Junge JA, Zheng M, Craft CM, Ameri H. PMID: 38248341; PMCID: PMC10813981.
      View in: PubMed   Mentions:    Fields:    
    4. Frequency and Pattern of Worldwide Ocular Gene Therapy Clinical Trials up to 2022. Biomedicines. 2023 Nov 23; 11(12). Ameri H, Kesavamoorthy N, Bruce DN. PMID: 38137345; PMCID: PMC10740821.
      View in: PubMed   Mentions:
    5. Effects of Smoothing and Adaptive Filtering in Multifocal Electroretinography (mfERG). J Clin Med. 2023 Aug 14; 12(16). Long CP, Ameri H. PMID: 37629328; PMCID: PMC10455984.
      View in: PubMed   Mentions:
    6. Hypertension: A Cause of Bilateral Proliferative Retinopathy. J Curr Ophthalmol. 2022 Oct-Dec; 34(4):478-482. Jung EE, Ameri H. PMID: 37180527; PMCID: PMC10170981.
      View in: PubMed   Mentions:
    7. Optical coherence tomography in healthy human subjects in the setting of prolonged dark adaptation. Sci Rep. 2023 03 06; 13(1):3725. Su EH, Kesavamoorthy N, Ameri H. PMID: 36879027; PMCID: PMC9988879.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    8. Sight restoration reverses blindness-induced cross-modal functional connectivity changes between the visual and somatosensory cortex at rest. Front Neurosci. 2022; 16:902866. Nadvar N, Stiles N, Choupan J, Patel V, Ameri H, Shi Y, Liu Z, Jonides J, Weiland J. PMID: 36213743; PMCID: PMC9539921.
      View in: PubMed   Mentions:
    9. Insights into Metabolic Activity and Structure of the Retina through Multiphoton Fluorescence Lifetime Imaging Microscopy in Mice. Cells. 2022 07 22; 11(15). Kesavamoorthy N, Junge JA, Fraser SE, Ameri H. PMID: 35892562; PMCID: PMC9331481.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    10. Capillary density and caliber as assessed by optical coherence tomography angiography may be significant predictors of diabetic retinopathy severity. PLoS One. 2022; 17(1):e0262996. Kushner-Lenhoff S, Kogachi K, Mert M, Chu Z, Shahidzadeh A, Palejwala NV, Wolfe J, Itty S, Drenser KA, Capone A, Dugel PU, Moshfeghi AA, Ameri H, Daskivich LP, Wang RK, Kashani AH. PMID: 35081154; PMCID: PMC8791516.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    11. Ischemic index and distribution of retinal capillary non-perfusion in neovascular glaucoma. Front Biosci (Landmark Ed). 2022 01 17; 27(1):24. DeBoer C, Wong B, Ameri H. PMID: 35090329.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    12. Acquired Vitelliform Macular Degeneration: Characteristics and Challenges of Managing Subretinal Fluid. J Ophthalmic Vis Res. 2021 Oct-Dec; 16(4):582-591. Juliano J, Patel S, Ameri H. PMID: 34840681; PMCID: PMC8593535.
      View in: PubMed   Mentions: 2  
    13. Visual Outcomes in Eyes With Neovascular Glaucoma and Anterior Segment Neovascularization Without Glaucoma. Am J Ophthalmol. 2022 04; 236:1-11. Sastry A, Ryu C, Jiang X, Ameri H. PMID: 34562418.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    14. Patterns of Autofluorescence in Common Genotypes of Retinitis Pigmentosa. Ophthalmic Surg Lasers Imaging Retina. 2021 08; 52(8):426-431. Dowd-Schoeman TJ, Rosenbloom J, Ameri H. PMID: 34410191.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    15. Fundus Autofluorescence and Clinical Applications. J Ophthalmic Vis Res. 2021 Jul-Sep; 16(3):432-461. Pole C, Ameri H. PMID: 34394872; PMCID: PMC8358768.
      View in: PubMed   Mentions: 12  
    16. Relating Retinal Vascular Oxygen Saturation and Microvasculature Morphology at Progressive Stages of Diabetic Retinopathy. Transl Vis Sci Technol. 2021 05 03; 10(6):4. Auvazian SL, Cano J, Leahy S, Karamian P, Kashani A, Moshfeghi A, Ameri H, Blair NP, Shahidi M. PMID: 34111249; PMCID: PMC8107511.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    17. Association of the Pattern of Retinal Capillary Non-Perfusion and Vascular Leakage with Retinal Neovascularization in Proliferative Diabetic Retinopathy. J Curr Ophthalmol. 2021 Jan-Mar; 33(1):56-61. Jung EE, Lin M, Ryu C, Moysidis SN, Burkemper B, Murgai R, Arbabi A, Ameri H. PMID: 34084958; PMCID: PMC8102955.
      View in: PubMed   Mentions: 6  
    18. Electroretinogram and Visual Field Correlation in Birdshot Chorioretinopathy. Asia Pac J Ophthalmol (Phila). 2021 Feb 03; 10(2):208-211. Ameri H, Naser M, Choudhury F, Rao NA. PMID: 33793442.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    19. Autofluorescence of choroidal vessels in Bietti's crystalline dystrophy. BMJ Open Ophthalmol. 2020; 5(1):e000592. Ameri H, Su E, Dowd-Schoeman TJ. PMID: 33178891; PMCID: PMC7594368.
      View in: PubMed   Mentions: 3     Fields:    
    20. Classification of advanced and early stages of diabetic retinopathy from non-diabetic subjects by an ordinary least squares modeling method applied to OCTA images. Biomed Opt Express. 2020 Aug 01; 11(8):4666-4678. Cano J, O'neill WD, Penn RD, Blair NP, Kashani AH, Ameri H, Kaloostian CL, Shahidi M. PMID: 32923070; PMCID: PMC7449717.
      View in: PubMed   Mentions: 3  
    21. Reduced Expression of VEGF-A in Human Retinal Pigment Epithelial Cells and Human Muller Cells Following CRISPR-Cas9 Ribonucleoprotein-Mediated Gene Disruption. Transl Vis Sci Technol. 2020 07; 9(8):23. Ameri H, Murat C, Arbabi A, Jiang W, Janga SR, Qin PZ, Hamm-Alvarez SF. PMID: 32855870; PMCID: PMC7422915.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    22. Enhanced Depth Navigation Through Augmented Reality Depth Mapping in Patients with Low Vision. Sci Rep. 2019 08 02; 9(1):11230. Angelopoulos AN, Ameri H, Mitra D, Humayun M. PMID: 31375713; PMCID: PMC6677879.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    23. Retinal Gene Distribution and Functionality Implicated in Inherited Retinal Degenerations Can Reveal Disease-Relevant Pathways for Pharmacologic Intervention. Pharmaceuticals (Basel). 2019 May 17; 12(2). Mustafi D, Arbabi A, Ameri H, Palczewski K. PMID: 31108889; PMCID: PMC6631933.
      View in: PubMed   Mentions: 4  
    24. Optical coherence tomography imaging of presumed Cryptococcus neoformans infection localized to the retina. J Curr Ophthalmol. 2019 Sep; 31(3):353-356. Wong BJ, Rao NA, Ameri H. PMID: 31528776; PMCID: PMC6742626.
      View in: PubMed   Mentions:
    25. Argus II Retinal Prosthesis Implantation in a Patient With a History Of Strabismus Surgery:A Surgical Technique. Ophthalmic Surg Lasers Imaging Retina. 2019 02 01; 50(2):116-119. Narala R, Humayun MS, Ameri H. PMID: 30768220.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    26. Gene Therapy for Inherited Retinal Degeneration. J Ocul Pharmacol Ther. 2019 03; 35(2):79-97. Arbabi A, Liu A, Ameri H. PMID: 30688548.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    27. VISUAL AND ANATOMICAL OUTCOMES AFTER DIABETIC TRACTION AND TRACTION-RHEGMATOGENOUS RETINAL DETACHMENT REPAIR. Retina. 2018 Oct; 38(10):1913-1919. Storey PP, Ter-Zakarian A, Philander SA, Olmos de Koo L, George M, Humayun MS, Rodger DC, Ameri H. PMID: 28796149.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    30. Retinal Anatomy and Electrode Array Position in Retinitis Pigmentosa Patients After Argus II Implantation: An International Study. Am J Ophthalmol. 2018 09; 193:87-99. Gregori NZ, Callaway NF, Hoeppner C, Yuan A, Rachitskaya A, Feuer W, Ameri H, Arevalo JF, Augustin AJ, Birch DG, Dagnelie G, Grisanti S, Davis JL, Hahn P, Handa JT, Ho AC, Huang SS, Humayun MS, Iezzi R, Jayasundera KT, Kokame GT, Lam BL, Lim JI, Mandava N, Montezuma SR, Olmos de Koo L, Szurman P, Vajzovic L, Wiedemann P, Weiland J, Yan J, Zacks DN. PMID: 29940167; PMCID: PMC6535141.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    31. Rapid Diagnostic for Point-of-Care Malaria Screening. ACS Sens. 2018 07 27; 3(7):1264-1270. McBirney SE, Chen D, Scholtz A, Ameri H, Armani AM. PMID: 29781606.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    32. Eplerenone as a novel treatment for persistent subretinal fluid following retinal detachment surgery. Am J Ophthalmol Case Rep. 2018 Jun; 10:261-263. Haghighi A, Do J, Ameri H. PMID: 29780947; PMCID: PMC5956724.
      View in: PubMed   Mentions: 3  
    33. Prospect of retinal gene therapy following commercialization of voretigene neparvovec-rzyl for retinal dystrophy mediated by RPE65 mutation. J Curr Ophthalmol. 2018 Mar; 30(1):1-2. Ameri H. PMID: 29564403; PMCID: PMC5859497.
      View in: PubMed   Mentions: 26  
    34. Implantation of multiple suprachoroidal electrode arrays in rabbits. J Curr Ophthalmol. 2018 Mar; 30(1):68-73. Abdallah W, Li W, Weiland J, Humayun M, Ameri H. PMID: 29564412; PMCID: PMC5859463.
      View in: PubMed   Mentions: 1  
    35. Acute hypotony maculopathy following the initiation of a topical aqueous suppressant in a patient with a history of panuveitis without prior filtering surgery. Am J Ophthalmol Case Rep. 2017 Sep; 7:95-98. Zhu D, Ameri H, Reznik A, Rao NA. PMID: 29260088; PMCID: PMC5722180.
      View in: PubMed   Mentions:
    36. Quantitative microvascular analysis of retinal venous occlusions by spectral domain optical coherence tomography angiography. PLoS One. 2017; 12(4):e0176404. Koulisis N, Kim AY, Chu Z, Shahidzadeh A, Burkemper B, Olmos de Koo LC, Moshfeghi AA, Ameri H, Puliafito CA, Isozaki VL, Wang RK, Kashani AH. PMID: 28437483; PMCID: PMC5402954.
      View in: PubMed   Mentions: 48     Fields:    Translation:Humans
    37. Atypical chronic central serous chorioretinopathy with cystoid macular edema: Therapeutic response to medical and laser therapy. J Curr Ophthalmol. 2017 Jun; 29(2):133-135. Do JL, Olmos de Koo LC, Ameri H. PMID: 28626824; PMCID: PMC5463008.
      View in: PubMed   Mentions: 3  
    38. Widefield OCT Findings of a Patient With Stellate Nonhereditary Idiopathic Foveomacular Retinoschisis. Ophthalmic Surg Lasers Imaging Retina. 2016 08 01; 47(8):774-7. Mandell JB, Kim AY, Shahidzadeh A, Ameri H, Puliafito CA, Moshfeghi AA. PMID: 27548456.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    39. Optical Coherence Tomography Angiography of Diabetic Retinopathy in Human Subjects. Ophthalmic Surg Lasers Imaging Retina. 2015 Sep; 46(8):796-805. Matsunaga DR, Yi JJ, De Koo LO, Ameri H, Puliafito CA, Kashani AH. PMID: 26431294.
      View in: PubMed   Mentions: 83     Fields:    Translation:Humans
    40. Type 3 neovascularization: evolution, association with pigment epithelial detachment, and treatment response as revealed by spectral domain optical coherence tomography. Retina. 2015 Apr; 35(4):638-47. Nagiel A, Sarraf D, Sadda SR, Spaide RF, Jung JJ, Bhavsar KV, Ameri H, Querques G, Freund KB. PMID: 25650713.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    41. MULTIMODAL IMAGING OF GEOGRAPHIC AREAS OF RETINAL DARKENING. Retin Cases Brief Rep. 2015; 9(4):347-51. Moysidis SN, Koulisis N, Ameri H, Matsunaga D, Yi J, Isozaki VL, Kashani AH, Olmos de Koo LC. PMID: 26421892.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    42. Retinal prosthesis, potential future approaches. Clin Exp Ophthalmol. 2014 Sep-Oct; 42(7):599-600. Ameri H. PMID: 25307555.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    43. TWEAK/Fn14 pathway is a novel mediator of retinal neovascularization. Invest Ophthalmol Vis Sci. 2014 Feb 10; 55(2):801-13. Ameri H, Liu H, Liu R, Ha Y, Paulucci-Holthauzen AA, Hu S, Motamedi M, Godley BF, Tilton RG, Zhang W. PMID: 24408972; PMCID: PMC3920863.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    44. Leuprolide monotherapy for choroidal metastasis from prostate adenocarcinoma. Arch Ophthalmol. 2012 Sep; 130(9):1225-6. Ameri H, Araujo JC, Gombos DS. PMID: 22965610.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    45. Neuroretinitis with retrobulbar involvement. J Neuroophthalmol. 2011 Mar; 31(1):12-5. Vaphiades MS, Wigton EH, Ameri H, Lee AG. PMID: 20613630.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    46. Vitreal oxygenation in retinal ischemia reperfusion. Invest Ophthalmol Vis Sci. 2011 Feb; 52(2):1035-42. Abdallah W, Ameri H, Barron E, Chader GJ, Greenbaum E, Hinton DR, Humayun MS. PMID: 21051734; PMCID: PMC3053094.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    47. Ultrasonic Doppler measurements of blood flow velocity of rabbit retinal vessels using a 45-MHz needle transducer. Graefes Arch Clin Exp Ophthalmol. 2010 May; 248(5):675-80. Matsuoka N, Paeng DG, Chen R, Ameri H, Abdallah W, Zhou Q, Fawzi A, Shung KK, Humayun M. PMID: 20162299; PMCID: PMC2847001.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    48. Toward a wide-field retinal prosthesis. J Neural Eng. 2009 Jun; 6(3):035002. Ameri H, Ratanapakorn T, Ufer S, Eckhardt H, Humayun MS, Weiland JD. PMID: 19458405; PMCID: PMC2861858.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    49. Natural course of experimental retinal vein occlusion in rabbit; arterial occlusion following venous photothrombosis. Graefes Arch Clin Exp Ophthalmol. 2008 Oct; 246(10):1429-39. Ameri H, Ratanapakorn T, Rao NA, Chader GJ, Humayun MS. PMID: 18642023.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    50. Intravitreal and subretinal injection of tissue plasminogen activator (tPA) in the treatment of experimentally created retinal vein occlusion in rabbits. Retina. 2008 Feb; 28(2):350-5. Ameri H, Kim JG, Ratanapakorn T, Chader GJ, Humayun MS. PMID: 18301042.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    51. The effects of intravitreous bevacizumab on retinal neovascular membrane and normal capillaries in rabbits. Invest Ophthalmol Vis Sci. 2007 Dec; 48(12):5708-15. Ameri H, Chader GJ, Kim JG, Sadda SR, Rao NA, Humayun MS. PMID: 18055823.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    52. Determining the acoustic properties of the lens using a high-frequency ultrasonic needle transducer. Ultrasound Med Biol. 2007 Dec; 33(12):1971-7. Huang CC, Zhou Q, Ameri H, Wu DW, Sun L, Wang SH, Humayun MS, Shung KK. PMID: 17673358.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    53. Evaluation of lens hardness in cataract surgery using high-frequency ultrasonic parameters in vitro. Ultrasound Med Biol. 2007 Oct; 33(10):1609-16. Huang CC, Ameri H, Deboer C, Rowley AP, Xu X, Sun L, Wang SH, Humayun MS, Shung KK. PMID: 17618041.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    54. PMN-PT single crystal, high-frequency ultrasonic needle transducers for pulsed-wave Doppler application. IEEE Trans Ultrason Ferroelectr Freq Control. 2007 Mar; 54(3):668-75. Zhou Q, Xu X, Gottlieb EJ, Sun L, Cannata JM, Ameri H, Humayun MS, Han P, Shung KK. PMID: 17375836.
      View in: PubMed   Mentions: 52     Fields:    
    55. Enucleated eye model for intraocular retinal prosthesis implantation. Ophthalmic Surg Lasers Imaging. 2006 Jul-Aug; 37(4):341-3. Ratanapakorn T, Ameri H, Humayun MS, Weiland JD. PMID: 16898401.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    56. Comparison of unilateral and simultaneous bilateral measurement of the globe position, using the Hertel exophthalmometer. Ophthalmic Plast Reconstr Surg. 2004 Nov; 20(6):448-51. Ameri H, Fenton S. PMID: 15599245.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    57. Permanent visual loss following traumatic cortical contusion. Eye (Lond). 2004 Oct; 18(10):1015-6. Ameri H, Murray A, Cleary PE, Spence LD. PMID: 15060558.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
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