Benjamin Yixing Xu

Title(s)Assistant Professor Of Clinical Ophthalmology
AddressHC4 3610 1450 San Pablo Street
Health Sciences Campus
Los Angeles CA 90033-6103
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    Other Positions
    Title(s)Director of Inpatient Ophthalmology Service

    Collapse Biography 
    Collapse Education and Training
    Columbia UniversityMD/PhD2012
    USC Roski Eye InstituteOphthalmology Residency2016
    University of California, San Diego, Shiley Eye Institute and Hamilton Glaucoma CenterGlaucoma Fellowship2017
    Collapse Awards and Honors
    2004  - 2008NIH Medical Scientist Training Program Training Grant
    2008MD/PhD Student Research Symposium Award
    2008  - 2009Columbia University Vision Sciences NEI Training Grant
    2009MD/PhD Student Research Symposium Award
    2011Dr. Alfred P. Steiner Dean's Day Research Award
    2015Medical Knowledge Award
    University of Southern California2016Resident Teaching Award

    Collapse Overview 
    Collapse Overview
    Dr. Xu attended Yale University where he graduated cum laude with a bachelor of science in biomedical engineering. He received his MD and PhD degrees from Columbia University where he was part of the NIH-sponsored Medical Scientist Training Program. He completed a well-received thesis studying how the brain uses eye position signals to coordinate accurate eye movements. Dr. Xu completed his residency in ophthalmology at the LAC+USC Medical Center and USC Roski Eye Institute, where he served as Chief Resident and was recognized for his academic and teaching achievements. He completed his glaucoma fellowship with Dr. Robert Weinreb at the UCSD Shiley Eye Institute and Hamilton Glaucoma Center.

    Dr. Xu’s primary research interest is preventing vision loss and blindness in patients at risk for angle closure glaucoma (ACG), a common type of glaucoma. His research focuses on studying the pathophysiology of ACG and improving the care of angle closure patients. Dr. Xu collaborates with Dr. Rohit Varma on his population-based eye studies such as the Chinese American Eye Study to identify risk factors for ACG and other ocular diseases. Dr. Xu also uses advanced anterior segment imaging modalities including anterior segment optical coherence tomography (AS-OCT) and ultrasound biomicroscopy (UBM) to study the physiological and biomechanical properties of intraocular structures and aqueous outflow pathways. Finally, Dr. Xu works on designing biomedical devices to assess the function of anterior segment structures, such as the iris and trabecular meshwork.

    Collapse Research 
    Collapse Research Activities and Funding
    Development and Validation of Quantitative Anterior Segment OCT-based Methods to Evaluate Patients with Primary Angle Closure Disease
    NIH K23EY029763Feb 1, 2019 - Jan 31, 2024
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Incidence of Proliferative Diabetic Retinopathy and Other Neovascular Sequelae at 5 Years Following Diagnosis of Type 2 Diabetes. Diabetes Care. 2021 Sep 02. Gange WS, Lopez J, Xu BY, Lung K, Seabury SA, Toy BC. PMID: 34475031.
      View in: PubMed   Mentions:    Fields:    
    2. Relationship Between Macular Vessel Density and Total Retinal Blood Flow in Primary Open-angle Glaucoma. J Glaucoma. 2021 Aug 01; 30(8):666-671. Cano J, Rahimi M, Xu BY, Richter GM, Tan O, Huang D, Shahidi M. PMID: 33979111.
      View in: PubMed   Mentions:    Fields:    
    3. Hemiretinal Asymmetry in Peripapillary Vessel Density in Healthy, Glaucoma Suspect, and Glaucoma Eyes. Am J Ophthalmol. 2021 Jun 05; 230:156-165. Hong KL, Burkemper B, Urrea AL, Chang BR, Lee JC, LeTran VH, Chu Z, Zhou X, Xu BY, Wong BJ, Song BJ, Jiang X, Wang RK, Varma R, Richter GM. PMID: 34102157.
      View in: PubMed   Mentions:    Fields:    
    4. Steps to Measurement Floor of an Optical Microangiography Device in Glaucoma. Am J Ophthalmol. 2021 May 26; 231:58-69. Phillips MJ, Dinh-Dang D, Bolo K, Burkemper B, Lee JC, LeTran VH, Chang BR, Grisafe DJ, Chu Z, Zhou X, Song BJ, Xu BY, Wong B, Wang RK, Richter GM. PMID: 34051173.
      View in: PubMed   Mentions:    Fields:    
    5. Assessing accommodative presbyopic biometric changes of the entire anterior segment using single swept-source OCT image acquisitions. Eye (Lond). 2021 Feb 25. Xie X, Sultan W, Corradetti G, Lee JY, Song A, Pardeshi A, Yu F, Chopra V, Sadda SR, Xu BY, Huang AS. PMID: 33633350.
      View in: PubMed   Mentions:    Fields:    
    6. Glaucoma Expert-Level Detection of Angle Closure in Goniophotographs With Convolutional Neural Networks: The Chinese American Eye Study. Am J Ophthalmol. 2021 06; 226:100-107. Chiang M, Guth D, Pardeshi AA, Randhawa J, Shen A, Shan M, Dredge J, Nguyen A, Gokoffski K, Wong BJ, Song B, Lin S, Varma R, Xu BY. PMID: 33577791.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Impact of Visual Field Loss on Vision-Specific Quality of Life in African Americans: The African American Eye Disease Study. Am J Ophthalmol. 2021 Feb 08; 229:52-62. Grisafe DJ, Varma R, Burkemper BS, Xu BY, Torres M, Fairbrother-Crisp A, Patino CM, McKean-Cowdin R, African American Eye Disease Study Group . PMID: 33571475.
      View in: PubMed   Mentions:    Fields:    
    8. Anatomic Changes and Predictors of Angle Widening after Laser Peripheral Iridotomy: The Zhongshan Angle Closure Prevention Trial. Ophthalmology. 2021 Aug; 128(8):1161-1168. Xu BY, Friedman DS, Foster PJ, Jiang Y, Pardeshi AA, Jiang Y, Munoz B, Aung T, He M. PMID: 33497730.
      View in: PubMed   Mentions:    Fields:    
    9. Age- and refraction-related changes in anterior segment anatomical structures measured by swept-source anterior segment OCT. PLoS One. 2020; 15(10):e0240110. Xie X, Corradetti G, Song A, Pardeshi A, Sultan W, Lee JY, Yu F, Zhang L, Chen S, Chopra V, Sadda SR, Xu B, Huang AS. PMID: 33095821.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    10. Differences in Ocular Biometric Measurements among Subtypes of Primary Angle Closure Disease: The Chinese American Eye Study. Ophthalmol Glaucoma. 2021 Mar-Apr; 4(2):224-231. Xu BY, Liang S, Pardeshi AA, Lifton J, Moghimi S, Lewinger JP, Varma R. PMID: 32942063.
      View in: PubMed   Mentions:
    11. Intrasession repeatability and intersession reproducibility of peripapillary OCTA vessel parameters in non-glaucomatous and glaucomatous eyes. Br J Ophthalmol. 2020 Sep 11. Lee JC, Grisafe DJ, Burkemper B, Chang BR, Zhou X, Chu Z, Fard A, Durbin M, Wong BJ, Song BJ, Xu BY, Wang R, Richter GM. PMID: 32917629.
      View in: PubMed   Mentions:    Fields:    
    12. Clinical Utility of Triplicate En Face Image Averaging for Optical Coherence Tomography Angiography in Glaucoma and Glaucoma Suspects. J Glaucoma. 2020 09; 29(9):823-830. Nelson AJ, Chu Z, Burkemper B, Chang BR, Xu B, Wang RK, Richter GM. PMID: 32496464.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Intradevice Repeatability and Interdevice Agreement of Ocular Biometric Measurements: A Comparison of Two Swept-Source Anterior Segment OCT Devices. Transl Vis Sci Technol. 2020 08; 9(9):14. Pardeshi AA, Song AE, Lazkani N, Xie X, Huang A, Xu BY. PMID: 32879770.
      View in: PubMed   Mentions:
    14. Ocular Biometric Determinants of Anterior Chamber Angle Width in Chinese Americans: The Chinese American Eye Study. Am J Ophthalmol. 2020 12; 220:19-26. Xu BY, Lifton J, Burkemper B, Jiang X, Pardeshi AA, Moghimi S, Richter GM, McKean-Cowdin R, Varma R. PMID: 32730913.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    15. Rates of Eye Care and Diabetic Eye Disease among Insured Patients with Newly Diagnosed Type 2 Diabetes. Ophthalmol Retina. 2021 02; 5(2):160-168. Gange WS, Xu BY, Lung K, Toy BC, Seabury SA. PMID: 32653554.
      View in: PubMed   Mentions:    Fields:    
    16. A Randomized Controlled Trial Comparing Subconjunctival Injection to Direct Scleral Application of Mitomycin C in Trabeculectomy. Am J Ophthalmol. 2020 12; 220:45-52. Do JL, Xu BY, Wong B, Camp A, Ngai P, Long C, Proudfoot J, Moghimi S, Yan D, Welsbie DS, Weinreb RN. PMID: 32645310.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    17. Deep Neural Network for Scleral Spur Detection in Anterior Segment OCT Images: The Chinese American Eye Study. Transl Vis Sci Technol. 2020 03; 9(2):18. Xu BY, Chiang M, Pardeshi AA, Moghimi S, Varma R. PMID: 32818079.
      View in: PubMed   Mentions:
    18. Effect of Angle Narrowing on Sectoral Variation of Anterior Chamber Angle Width: The Chinese American Eye Study. Ophthalmol Glaucoma. 2020 Mar-Apr; 3(2):130-138. Xu BY, Pardeshi AA, Shan J, DeBoer C, Moghimi S, Richter G, McKean-Cowdin R, Varma R. PMID: 32632408.
      View in: PubMed   Mentions:
    19. Vessel density and retinal nerve fibre layer thickness following acute primary angle closure. Br J Ophthalmol. 2020 08; 104(8):1103-1108. Moghimi S, SafiZadeh M, Xu BY, Fard MA, Khatibi N, Rao HL, Weinreb RN. PMID: 31676595.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    20. Surgical Management of Primary Angle-Closure Disease-Why Less Is More. JAMA Ophthalmol. 2019 Oct 01; 137(10):1113-1114. Xu BY, Varma R. PMID: 31294767.
      View in: PubMed   Mentions:    Fields:    
    21. Deep Learning Classifiers for Automated Detection of Gonioscopic Angle Closure Based on Anterior Segment OCT Images. Am J Ophthalmol. 2019 12; 208:273-280. Xu BY, Chiang M, Chaudhary S, Kulkarni S, Pardeshi AA, Varma R. PMID: 31445003.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    22. Ocular Determinants of Peripapillary Vessel Density in Healthy African Americans: The African American Eye Disease Study. Invest Ophthalmol Vis Sci. 2019 08 01; 60(10):3368-3373. Nelson AJ, Chang R, LeTran V, Vu B, Burkemper B, Chu Z, Fard A, Kashani A, Xu B, Wang R, Varma R, Richter GM, African American Eye Disease Study Group . PMID: 31917454.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    23. Systemic Determinants of Peripapillary Vessel Density in Healthy African Americans: The African American Eye Disease Study. Am J Ophthalmol. 2019 11; 207:240-247. Chang R, Nelson AJ, LeTran V, Vu B, Burkemper B, Chu Z, Fard A, Kashani AH, Xu BY, Wang RK, Varma R, Richter GM, African American Eye Disease Study Group . PMID: 31229463.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    24. Effect of Scan Size on Glaucoma Diagnostic Performance Using OCT Angiography En Face Images of the Radial Peripapillary Capillaries. J Glaucoma. 2019 05; 28(5):465-472. Chang R, Chu Z, Burkemper B, Lee GC, Fard A, Durbin MK, Reznik A, Xu BY, Kashani A, Varma R, Wang RK, Richter GM. PMID: 30789527.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    25. Anterior Segment Optical Coherence Tomography: Applications for Clinical Care and Scientific Research. Asia Pac J Ophthalmol (Phila). 2019 Apr 25. Shan J, DeBoer C, Xu BY. PMID: 31020820.
      View in: PubMed   Mentions: 7     Fields:    
    26. Differences in Anterior Chamber Angle Assessments Between Gonioscopy, EyeCam, and Anterior Segment OCT: The Chinese American Eye Study. Transl Vis Sci Technol. 2019 Mar; 8(2):5. Xu BY, Pardeshi AA, Burkemper B, Richter GM, Lin SC, McKean-Cowdin R, Varma R. PMID: 30941263.
      View in: PubMed   Mentions:
    27. Quantitative Evaluation of Gonioscopic and EyeCam Assessments of Angle Dimensions Using Anterior Segment Optical Coherence Tomography. Transl Vis Sci Technol. 2018 Nov; 7(6):33. Xu BY, Pardeshi AA, Burkemper B, Richter GM, Lin SC, McKean-Cowdin R, Varma R. PMID: 30619653.
      View in: PubMed   Mentions:
    28. Correlation between Intraocular Pressure and Angle Configuration Measured by OCT: The Chinese American Eye Study. Ophthalmol Glaucoma. 2018 Nov-Dec; 1(3):158-166. Xu BY, Burkemper B, Lewinger JP, Jiang X, Pardeshi AA, Richter G, Torres M, McKean-Cowdin R, Varma R. PMID: 31025032.
      View in: PubMed   Mentions:
    29. Diurnal Variation of Optical Coherence Tomography Measurements of Static and Dynamic Anterior Segment Parameters. J Glaucoma. 2018 01; 27(1):16-21. Xu BY, Penteado RC, Weinreb RN. PMID: 29194197.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    30. Reproducibility and Agreement of Anterior Segment Parameter Measurements Obtained Using the CASIA2 and Spectralis OCT2 Optical Coherence Tomography Devices. J Glaucoma. 2017 Nov; 26(11):974-979. Xu BY, Mai DD, Penteado RC, Saunders L, Weinreb RN. PMID: 28930883.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    31. Aqueous Angiography: Aqueous Humor Outflow Imaging in Live Human Subjects. Ophthalmology. 2017 08; 124(8):1249-1251. Huang AS, Camp A, Xu BY, Penteado RC, Weinreb RN. PMID: 28461013.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    32. Benefit of Measuring Anterior Segment Structures Using an Increased Number of Optical Coherence Tomography Images: The Chinese American Eye Study. Invest Ophthalmol Vis Sci. 2016 11 01; 57(14):6313-6319. Xu BY, Israelsen P, Pan BX, Wang D, Jiang X, Varma R. PMID: 27893097.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    33. The postsaccadic unreliability of gain fields renders it unlikely that the motor system can use them to calculate target position in space. Neuron. 2012 Dec 20; 76(6):1201-9. Xu BY, Karachi C, Goldberg ME. PMID: 23259954.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
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