Benjamin Yixing Xu

Title(s)Assistant Professor Of Clinical Ophthalmology
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    Other Positions
    Title(s)Director of Inpatient Ophthalmology Service

    Collapse Biography 
    Collapse Education and Training
    Columbia UniversityMD/PhD2012
    USC Roski Eye InstituteOphthalmology Residency2016
    University of California, San Diego, Shiley Eye Institute and Hamilton Glaucoma CenterGlaucoma Fellowship2017
    Collapse Awards and Honors
    2004  - 2008NIH Medical Scientist Training Program Training Grant
    2008MD/PhD Student Research Symposium Award
    2008  - 2009Columbia University Vision Sciences NEI Training Grant
    2009MD/PhD Student Research Symposium Award
    2011Dr. Alfred P. Steiner Dean's Day Research Award
    2015Medical Knowledge Award
    University of Southern California2016Resident Teaching Award

    Collapse Overview 
    Collapse Overview
    Dr. Xu attended Yale University where he graduated cum laude with a bachelor of science in biomedical engineering. He received his MD and PhD degrees from Columbia University where he was part of the NIH-sponsored Medical Scientist Training Program. He completed a well-received thesis studying how the brain uses eye position signals to coordinate accurate eye movements. Dr. Xu completed his residency in ophthalmology at the LAC+USC Medical Center and USC Roski Eye Institute, where he served as Chief Resident and was recognized for his academic and teaching achievements. He completed his glaucoma fellowship with Dr. Robert Weinreb at the UCSD Shiley Eye Institute and Hamilton Glaucoma Center.

    Dr. Xu’s primary research interest is preventing vision loss and blindness in patients at risk for angle closure glaucoma (ACG), a common type of glaucoma. His research focuses on studying the pathophysiology of ACG and improving the care of angle closure patients. Dr. Xu collaborates with Dr. Rohit Varma on his population-based eye studies such as the Chinese American Eye Study to identify risk factors for ACG and other ocular diseases. Dr. Xu also uses advanced anterior segment imaging modalities including anterior segment optical coherence tomography (AS-OCT) and ultrasound biomicroscopy (UBM) to study the physiological and biomechanical properties of intraocular structures and aqueous outflow pathways. Finally, Dr. Xu works on designing biomedical devices to assess the function of anterior segment structures, such as the iris and trabecular meshwork.

    Collapse Research 
    Collapse Research Activities and Funding
    Development and Validation of Quantitative Anterior Segment OCT-based Methods to Evaluate Patients with Primary Angle Closure Disease
    NIH/NEI K23EY029763Feb 1, 2019 - Jan 31, 2024
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Moghimi S, SafiZadeh M, Xu BY, Fard MA, Khatibi N, Rao HL, Weinreb RN. Vessel density and retinal nerve fibre layer thickness following acute primary angle closure. Br J Ophthalmol. 2019 Nov 01. PMID: 31676595.
      View in: PubMed
    2. Xu BY, Chiang M, Chaudhary S, Kulkarni S, Pardeshi AA, Varma R. Deep Learning Classifiers for Automated Detection of Gonioscopic Angle Closure Based on Anterior Segment OCT Images. Am J Ophthalmol. 2019 Dec; 208:273-280. PMID: 31445003.
      View in: PubMed
    3. Nelson AJ, Chang R, LeTran V, Vu B, Burkemper B, Chu Z, Fard A, Kashani A, Xu B, Wang R, Varma R, Richter GM. Ocular Determinants of Peripapillary Vessel Density in Healthy African Americans: The African American Eye Disease Study. Invest Ophthalmol Vis Sci. 2019 08 01; 60(10):3368-3373. PMID: 31917454.
      View in: PubMed
    4. Xu BY, Varma R. Surgical Management of Primary Angle-Closure Disease-Why Less Is More. JAMA Ophthalmol. 2019 Jul 11. PMID: 31294767.
      View in: PubMed
    5. Chang R, Nelson AJ, LeTran V, Vu B, Burkemper B, Chu Z, Fard A, Kashani AH, Xu BY, Wang RK, Varma R, Richter GM. Systemic Determinants of Peripapillary Vessel Density in Healthy African Americans: The African American Eye Disease Study. Am J Ophthalmol. 2019 Nov; 207:240-247. PMID: 31229463.
      View in: PubMed
    6. Chang R, Chu Z, Burkemper B, Lee GC, Fard A, Durbin MK, Reznik A, Xu BY, Kashani A, Varma R, Wang RK, Richter GM. Effect of Scan Size on Glaucoma Diagnostic Performance Using OCT Angiography En Face Images of the Radial Peripapillary Capillaries. J Glaucoma. 2019 May; 28(5):465-472. PMID: 30789527.
      View in: PubMed
    7. Shan J, DeBoer C, Xu BY. Anterior Segment Optical Coherence Tomography: Applications for Clinical Care and Scientific Research. Asia Pac J Ophthalmol (Phila). 2019 Apr 25. PMID: 31020820.
      View in: PubMed
    8. Xu BY, Pardeshi AA, Burkemper B, Richter GM, Lin SC, McKean-Cowdin R, Varma R. Differences in Anterior Chamber Angle Assessments Between Gonioscopy, EyeCam, and Anterior Segment OCT: The Chinese American Eye Study. Transl Vis Sci Technol. 2019 Mar; 8(2):5. PMID: 30941263.
      View in: PubMed
    9. Xu BY, Pardeshi AA, Burkemper B, Richter GM, Lin SC, McKean-Cowdin R, Varma R. Quantitative Evaluation of Gonioscopic and EyeCam Assessments of Angle Dimensions Using Anterior Segment Optical Coherence Tomography. Transl Vis Sci Technol. 2018 Nov; 7(6):33. PMID: 30619653.
      View in: PubMed
    10. Xu BY, Burkemper B, Lewinger JP, Jiang X, Pardeshi AA, Richter G, Torres M, McKean-Cowdin R, Varma R. Correlation between Intraocular Pressure and Angle Configuration Measured by OCT: The Chinese American Eye Study. Ophthalmol Glaucoma. 2018 Nov-Dec; 1(3):158-166. PMID: 31025032.
      View in: PubMed
    11. Xu BY, Penteado RC, Weinreb RN. Diurnal Variation of Optical Coherence Tomography Measurements of Static and Dynamic Anterior Segment Parameters. J Glaucoma. 2018 01; 27(1):16-21. PMID: 29194197.
      View in: PubMed
    12. Xu BY, Mai DD, Penteado RC, Saunders L, Weinreb RN. Reproducibility and Agreement of Anterior Segment Parameter Measurements Obtained Using the CASIA2 and Spectralis OCT2 Optical Coherence Tomography Devices. J Glaucoma. 2017 Nov; 26(11):974-979. PMID: 28930883.
      View in: PubMed
    13. Huang AS, Camp A, Xu BY, Penteado RC, Weinreb RN. Aqueous Angiography: Aqueous Humor Outflow Imaging in Live Human Subjects. Ophthalmology. 2017 08; 124(8):1249-1251. PMID: 28461013.
      View in: PubMed
    14. Xu BY, Israelsen P, Pan BX, Wang D, Jiang X, Varma R. Benefit of Measuring Anterior Segment Structures Using an Increased Number of Optical Coherence Tomography Images: The Chinese American Eye Study. Invest Ophthalmol Vis Sci. 2016 11 01; 57(14):6313-6319. PMID: 27893097.
      View in: PubMed
    15. Xu BY, Karachi C, Goldberg ME. The postsaccadic unreliability of gain fields renders it unlikely that the motor system can use them to calculate target position in space. Neuron. 2012 Dec 20; 76(6):1201-9. PMID: 23259954.
      View in: PubMed