Dat Phuc Ha

Title(s)Postdoctoral Scholar - Research Associate
SchoolKeck School of Medicine of Usc
AddressNOR 5307
Health Sciences Campus
Los Angeles CA 90089-9176
Phone+1 323 865 0506
EmailDATHA@USC.EDU
ORCID ORCID Icon0000-0002-2592-1223 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of California Irvine, Irvine, CABachelor of Science08/2010Biochemistry and Molecular Biology
    University of California Irvine, Irvine, CAMaster of Science06/2012Biological Sciences
    University of Southern California, Los Angeles, CADoctor of Philosophy08/2021Cancer Biology and Genomics

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Targeting stress induction of GRP78 by cardiac glycoside oleandrin dually suppresses cancer and COVID-19. Cell Biosci. 2024 Sep 06; 14(1):115. Ha DP, Shin WJ, Liu Z, Doche ME, Lau R, Leli NM, Conn CS, Russo M, Lorenzato A, Koumenis C, Yu M, Mumenthaler SM, Lee AS. PMID: 39238058; PMCID: PMC11378597.
      View in: PubMed   Mentions:
    2. GRP78 inhibitor YUM70 upregulates 4E-BP1 and suppresses c-MYC expression and viability of oncogenic c-MYC tumors. Neoplasia. 2024 09; 55:101020. Yamamoto V, Ha DP, Liu Z, Huang M, Samanta S, Neamati N, Lee AS. PMID: 38991376; PMCID: PMC11294750.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    3. ER chaperone GRP78/BiP translocates to the nucleus under stress and acts as a transcriptional regulator. Proc Natl Acad Sci U S A. 2023 08; 120(31):e2303448120. Liu Z, Liu G, Ha DP, Wang J, Xiong M, Lee AS. PMID: 37487081; PMCID: PMC10400976.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    4. GRP78 Inhibitor YUM70 Suppresses SARS-CoV-2 Viral Entry, Spike Protein Production and Ameliorates Lung Damage. Viruses. 2023 05 06; 15(5). Ha DP, Shin WJ, Hernandez JC, Neamati N, Dubeau L, Machida K, Lee AS. PMID: 37243204; PMCID: PMC10220750.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    5. The stress-inducible ER chaperone GRP78/BiP is upregulated during SARS-CoV-2 infection and acts as a pro-viral protein. Nat Commun. 2022 11 14; 13(1):6551. Shin WJ, Ha DP, Machida K, Lee AS. PMID: 36376289; PMCID: PMC9663498.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    6. Targeting GRP78 suppresses oncogenic KRAS protein expression and reduces viability of cancer cells bearing various KRAS mutations. Neoplasia. 2022 11; 33:100837. Ha DP, Huang B, Wang H, Rangel DF, Van Krieken R, Liu Z, Samanta S, Neamati N, Lee AS. PMID: 36162331; PMCID: PMC9516447.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    7. Suppression of ER-stress induction of GRP78 as an anti-neoplastic mechanism of the cardiac glycoside Lanatoside C in pancreatic cancer: Lanatoside C suppresses GRP78 stress induction. Neoplasia. 2021 12; 23(12):1213-1226. Ha DP, Tsai YL, Lee AS. PMID: 34768108; PMCID: PMC8591401.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    8. ER residential chaperone GRP78 unconventionally relocalizes to the cell surface via endosomal transport. Cell Mol Life Sci. 2021 Jun; 78(12):5179-5195. Van Krieken R, Tsai YL, Carlos AJ, Ha DP, Lee AS. PMID: 33974094; PMCID: PMC8254793.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    9. The chaperone GRP78 is a host auxiliary factor for SARS-CoV-2 and GRP78 depleting antibody blocks viral entry and infection. J Biol Chem. 2021 Jan-Jun; 296:100759. Carlos AJ, Ha DP, Yeh DW, Van Krieken R, Tseng CC, Zhang P, Gill P, Machida K, Lee AS. PMID: 33965375; PMCID: PMC8102082.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansAnimalsCells
    10. Endoplasmic reticulum chaperone GRP78/BiP is critical for mutant Kras-driven lung tumorigenesis. Oncogene. 2021 05; 40(20):3624-3632. Rangel DF, Dubeau L, Park R, Chan P, Ha DP, Pulido MA, Mullen DJ, Vorobyova I, Zhou B, Borok Z, Offringa IA, Lee AS. PMID: 33931739; PMCID: PMC8179725.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    11. Insulin-like growth factor 1-receptor signaling stimulates GRP78 expression through the PI3K/AKT/mTOR/ATF4 axis. Cell Signal. 2020 11; 75:109736. Ha DP, Lee AS. PMID: 32805346; PMCID: PMC7530066.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    12. The stress-inducible molecular chaperone GRP78 as potential therapeutic target for coronavirus infection. J Infect. 2020 09; 81(3):452-482. Ha DP, Van Krieken R, Carlos AJ, Lee AS. PMID: 32535155; PMCID: PMC7289740.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    13. Suppression of stress induction of the 78-kilodalton glucose regulated protein (GRP78) in cancer by IT-139, an anti-tumor ruthenium small molecule inhibitor. Oncotarget. 2018 Jul 03; 9(51):29698-29714. Bakewell SJ, Rangel DF, Ha DP, Sethuraman J, Crouse R, Hadley E, Costich TL, Zhou X, Nichols P, Lee AS. PMID: 30038714; PMCID: PMC6049868.
      View in: PubMed   Mentions: 21     Fields:    
    14. Endoplasmic reticulum stress activates SRC, relocating chaperones to the cell surface where GRP78/CD109 blocks TGF-β signaling. Proc Natl Acad Sci U S A. 2018 05 01; 115(18):E4245-E4254. Tsai YL, Ha DP, Zhao H, Carlos AJ, Wei S, Pun TK, Wu K, Zandi E, Kelly K, Lee AS. PMID: 29654145; PMCID: PMC5939063.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansCells
    15. New role of endoplasmic reticulum chaperones in regulating metaplasia during tumorigenesis. Mol Cell Oncol. 2017; 4(6):e1345350. Shen J, Rangel DF, Ha D, Lee AS. PMID: 29209644; PMCID: PMC5706948.
      View in: PubMed   Mentions: 1  
    16. GRP78 haploinsufficiency suppresses acinar-to-ductal metaplasia, signaling, and mutant Kras-driven pancreatic tumorigenesis in mice. Proc Natl Acad Sci U S A. 2017 05 16; 114(20):E4020-E4029. Shen J, Ha DP, Zhu G, Rangel DF, Kobielak A, Gill PS, Groshen S, Dubeau L, Lee AS. PMID: 28461470; PMCID: PMC5441757.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    17. Human and murine APOBEC3s restrict replication of koala retrovirus by different mechanisms. Retrovirology. 2015 Aug 08; 12:68. Nitta T, Ha D, Galvez F, Miyazawa T, Fan H. PMID: 26253512; PMCID: PMC4528783.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    18. Targeted deletion of ER chaperone GRP94 in the liver results in injury, repopulation of GRP94-positive hepatocytes, and spontaneous hepatocellular carcinoma development in aged mice. Neoplasia. 2014 Aug; 16(8):617-26. Chen WT, Ha D, Kanel G, Lee AS. PMID: 25220589; PMCID: PMC4235012.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    19. Murine leukemia virus glycosylated Gag blocks apolipoprotein B editing complex 3 and cytosolic sensor access to the reverse transcription complex. Proc Natl Acad Sci U S A. 2013 May 28; 110(22):9078-83. Stavrou S, Nitta T, Kotla S, Ha D, Nagashima K, Rein AR, Fan H, Ross SR. PMID: 23671100; PMCID: PMC3670389.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    20. Moloney murine leukemia virus glyco-gag facilitates xenotropic murine leukemia virus-related virus replication through human APOBEC3-independent mechanisms. Retrovirology. 2012 Jul 24; 9:58. Nitta T, Lee S, Ha D, Arias M, Kozak CA, Fan H. PMID: 22828015; PMCID: PMC3423011.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
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