Priya Jayachandran

Title(s)Assistant Professor of Clinical Medicine
SchoolKeck School of Medicine of Usc
Address1520 San Pablo St.
Health Sciences Campus
Los Angeles CA 90033
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    Title(s)Director of LAC Breast Medical Oncology and Genomics


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    Dr. Jayachandran specializes in Breast Medical Oncology. She is an Assistant Professor of Clinical Medicine at Keck and also serves as the Director of Breast Medical Oncology and Genomics at the LAC+USC Medical Center. She graduated from Stanford University and the University of Michigan Medical School before completing her residency in Internal Medicine at UCSF Fresno and fellowship in Hematology/Oncology at USC. She is active in research with a focus on clinical trials, translational studies, biomarkers, and improving access to care. She enjoys teaching fellows, residents, and medical students.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Differential responses to immune checkpoint inhibitors are governed by diverse mismatch repair gene alterations. Clin Cancer Res. 2024 Feb 13. Khushman MM, Toboni MD, Xiu J, Manne U, Farrell A, Lou E, Shields AF, Philip PA, Salem ME, Abraham J, Spetzler D, Marshall J, Jayachandran P, Hall MJ, Lenz HJ, Sahin IH, Seeber A, Powell MA. PMID: 38350001.
      View in: PubMed   Mentions:    Fields:    
    2. Predictive value of CDC37 gene expression for targeted therapy in metastatic colorectal cancer. Eur J Cancer. 2024 Apr; 201:113914. Arai H, Yang Y, Baca Y, Millstein J, Denda T, Ou FS, Innocenti F, Takeda H, Kubota Y, Doi A, Horie Y, Umemoto K, Izawa N, Wang J, Battaglin F, Jayachandran P, Algaze S, Soni S, Zhang W, Goldberg RM, Hall MJ, Scott AJ, Hwang JJ, Lou E, Weinberg BA, Marshall J, Goel S, Xiu J, Michael Korn W, Venook AP, Sunakawa Y, Lenz HJ. PMID: 38359495.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. CCR5 and CCL5 gene expression in colorectal cancer: comprehensive profiling and clinical value. J Immunother Cancer. 2024 01 11; 12(1). Battaglin F, Baca Y, Millstein J, Yang Y, Xiu J, Arai H, Wang J, Ou FS, Innocenti F, Mumenthaler SM, Jayachandran P, Kawanishi N, Lenz A, Soni S, Algaze S, Zhang W, Khoukaz T, Roussos Torres E, Seeber A, Abraham JP, Lou E, Philip PA, Weinberg BA, Shields AF, Goldberg RM, Marshall JL, Venook AP, Korn WM, Lenz HJ. PMID: 38212126; PMCID: PMC10806545.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. BRAF V600E/RAS Mutations and Lynch Syndrome in Patients With MSI-H/dMMR Metastatic Colorectal Cancer Treated With Immune Checkpoint Inhibitors. Oncologist. 2023 09 07; 28(9):771-779. Colle R, Lonardi S, Cachanado M, Overman MJ, Elez E, Fakih M, Corti F, Jayachandran P, Svrcek M, Dardenne A, Cervantes B, Duval A, Cohen R, Pietrantonio F, André T. PMID: 37023721; PMCID: PMC10485382.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    5. Invasive squamous cell carcinoma of the breast associated with breast augmentation implant capsule. J Surg Oncol. 2023 Sep; 128(4):495-501. Rosenberg K, McGillen P, Zanfagnin V, Lee S, Janaki N, Raicu A, Jayachandran P, Bian S, Yenikomshian H, Sener SF. PMID: 37260104.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. Axillary lymph node recurrence following wire-directed sentinel lymph node dissection for breast cancer patients with biopsy-proven axillary metastases prior to neoadjuvant chemotherapy at a safety net medical center. J Surg Oncol. 2023 Jul; 128(1):9-15. Sargent RE, Siegel E, Ito F, Kramme K, Kraft E, Hendrix V, Carr AA, Nelson ME, Bian SX, Jayachandran P, Sener SF. PMID: 36933187.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    7. Breast cancer and neurotransmitters: emerging insights on mechanisms and therapeutic directions. Oncogene. 2023 02; 42(9):627-637. Jayachandran P, Battaglin F, Strelez C, Lenz A, Algaze S, Soni S, Lo JH, Yang Y, Millstein J, Zhang W, Shih JC, Lu J, Mumenthaler SM, Spicer D, Neman J, Roussos Torres ET, Lenz HJ. PMID: 36650218; PMCID: PMC9957733.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    8. Association of immune-related adverse events with the outcomes of immune checkpoint inhibitors in patients with dMMR/MSI-H metastatic colorectal cancer. J Immunother Cancer. 2023 01; 11(1). Nasca V, Barretta F, Corti F, Lonardi S, Niger M, Elez ME, Fakih M, Jayachandran P, Shah AT, Salati M, Fenocchio E, Salvatore L, Cremolini C, Ros J, Ambrosini M, Mazzoli G, Intini R, Overman MJ, Miceli R, Pietrantonio F. PMID: 36593068; PMCID: PMC9809233.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    9. Neurotransmitter signaling: a new frontier in colorectal cancer biology and treatment. Oncogene. 2022 10; 41(43):4769-4778. Battaglin F, Jayachandran P, Strelez C, Lenz A, Algaze S, Soni S, Lo JH, Yang Y, Millstein J, Zhang W, Roussos Torres ET, Shih JC, Mumenthaler SM, Neman J, Lenz HJ. PMID: 36182970; PMCID: PMC10591256.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    10. Modeling the Probability of HIV Infection over Time in High-Risk Seronegative Participants Receiving Placebo in Five Randomized Double-Blind Placebo-Controlled HIV Pre-Exposure Prophylaxis Trials: A Patient-Level Pooled Analysis. Pharmaceutics. 2022 Aug 27; 14(9). Garcia-Cremades M, Hendrix CW, Jayachandran P, Strydom N, Jarlsberg L, Grant R, Celum CL, Martin M, Baeten JM, Marrazzo J, Anderson P, Choopanya K, Vanichseni S, Glidden DV, Savic RM. PMID: 36145549; PMCID: PMC9504389.
      View in: PubMed   Mentions: 1  
    11. Prognostic impact of performance status on the outcomes of immune checkpoint inhibition strategies in patients with dMMR/MSI-H metastatic colorectal cancer. Eur J Cancer. 2022 09; 172:171-181. Mazzoli G, Cohen R, Lonardi S, Corti F, Elez E, Fakih M, Jayachandran P, Colle R, Shah AT, Salati M, Fenocchio E, Salvatore L, Ambrosini M, Ros J, Intini R, Cremolini C, Overman MJ, André T, Pietrantonio F. PMID: 35777274.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    12. Genetic variants involved in the cGAS-STING pathway predict outcome in patients with metastatic colorectal cancer: Data from FIRE-3 and TRIBE trials. Eur J Cancer. 2022 09; 172:22-30. Wang J, Xiao Y, Loupakis F, Stintzing S, Yang Y, Arai H, Battaglin F, Kawanishi N, Jayachandran P, Soni S, Zhang W, Mancao C, Cremolini C, Liu T, Heinemann V, Falcone A, Shen L, Millstein J, Lenz HJ. PMID: 35749909.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. fdrci: FDR confidence interval selection and adjustment for large-scale hypothesis testing. Bioinform Adv. 2022; 2(1):vbac047. Millstein J, Battaglin F, Arai H, Zhang W, Jayachandran P, Soni S, Parikh AR, Mancao C, Lenz HJ. PMID: 35747247; PMCID: PMC9210923.
      View in: PubMed   Mentions: 4  
    14. Germline Polymorphisms in Genes Involved in the Antioxidant System Predict the Efficacy of Cetuximab in Metastatic Colorectal Cancer Patients Enrolled in FIRE-3 Trial. Clin Colorectal Cancer. 2022 09; 21(3):259-266. Arai H, Millstein J, Yang Y, Stintzing S, Wang J, Battaglin F, Kawanishi N, Jayachandran P, Soni S, Zhang W, Heinemann V, Lenz HJ. PMID: 35710481.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsCTClinical Trials
    15. Disease characterization in liquid biopsy from HER2-mutated, non-amplified metastatic breast cancer patients treated with neratinib. NPJ Breast Cancer. 2022 Feb 18; 8(1):22. Shishido SN, Masson R, Xu L, Welter L, Prabakar RK, D' Souza A, Spicer D, Kang I, Jayachandran P, Hicks J, Lu J, Kuhn P. PMID: 35181666; PMCID: PMC8857263.
      View in: PubMed   Mentions: 6  
    16. Ascites and resistance to immune checkpoint inhibition in dMMR/MSI-H metastatic colorectal and gastric cancers. J Immunother Cancer. 2022 02; 10(2). Fucà G, Cohen R, Lonardi S, Shitara K, Elez ME, Fakih M, Chao J, Klempner SJ, Emmett M, Jayachandran P, Bergamo F, García MD, Mazzoli G, Provenzano L, Colle R, Svrcek M, Ambrosini M, Randon G, Shah AT, Salati M, Fenocchio E, Salvatore L, Chida K, Kawazoe A, Conca V, Curigliano G, Corti F, Cremolini C, Overman M, Andre T, Pietrantonio F. PMID: 35110358; PMCID: PMC8811606.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    17. Molecular characteristics and clinical outcomes of patients with Neurofibromin 1-altered metastatic colorectal cancer. Oncogene. 2022 01; 41(2):260-267. Arai H, Elliott A, Millstein J, Xiu J, Ou FS, Innocenti F, Wang J, Battaglin F, Jayachandran P, Kawanishi N, Soni S, Zhang W, Sohal D, Goldberg RM, Hall MJ, Scott AJ, Khushman M, Hwang JJ, Lou E, Weinberg BA, Lockhart AC, Shields AF, Abraham JP, Magee D, Stafford P, Zhang J, Venook AP, Korn WM, Lenz HJ. PMID: 34728807; PMCID: PMC8738154.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    18. Germline polymorphisms in genes maintaining the replication fork predict the efficacy of oxaliplatin and irinotecan in patients with metastatic colorectal cancer. Br J Cancer. 2022 01; 126(1):72-78. Arai H, Xiao Y, Millstein J, Wang J, Battaglin F, Kawanishi N, Jayachandran P, Soni S, Zhang W, Mancao C, Salhia B, Mumenthaler SM, Parikh AR, Lenz HJ. PMID: 34689170; PMCID: PMC8727586.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsCTClinical Trials
    19. Clinical Significance of Circulating Tumor Cell Induced Epithelial-Mesenchymal Transition in Patients with Metastatic Colorectal Cancer by Single-Cell RNA-Sequencing. Cancers (Basel). 2021 Sep 28; 13(19). Kozuka M, Battaglin F, Jayachandran P, Wang J, Arai H, Soni S, Zhang W, Hirai M, Matsusaka S, Lenz HJ. PMID: 34638346; PMCID: PMC8507666.
      View in: PubMed   Mentions: 5  
    20. Nomogram to predict the outcomes of patients with microsatellite instability-high metastatic colorectal cancer receiving immune checkpoint inhibitors. J Immunother Cancer. 2021 08; 9(8). Pietrantonio F, Lonardi S, Corti F, Infante G, Elez ME, Fakih M, Jayachandran P, Shah AT, Salati M, Fenocchio E, Salvatore L, Curigliano G, Cremolini C, Ambrosini M, Ros J, Intini R, Nappo F, Damian S, Morano F, Fucà G, Overman M, Miceli R. PMID: 34429334; PMCID: PMC8386222.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    21. Germ line polymorphisms of genes involved in pluripotency transcription factors predict efficacy of cetuximab in metastatic colorectal cancer. Eur J Cancer. 2021 06; 150:133-142. Arai H, Millstein J, Loupakis F, Stintzing S, Wang J, Battaglin F, Kawanishi N, Jayachandran P, Soni S, Zhang W, Mumenthaler SM, Cremolini C, Heinemann V, Falcone A, Lenz HJ. PMID: 33901792.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    22. Clinical Pharmacokinetics of Oral Sodium Selenite and Dosing Implications in the Treatment of Patients with Metastatic Cancer. Drugs R D. 2021 Jun; 21(2):169-178. Jayachandran P, Knox SJ, Garcia-Cremades M, Savic RM. PMID: 33866531; PMCID: PMC8206290.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    23. A Mechanistic In Vivo/Ex Vivo Pharmacokinetic-Pharmacodynamic Model of Tenofovir for HIV Prevention. CPT Pharmacometrics Syst Pharmacol. 2021 03; 10(3):179-187. Jayachandran P, Garcia-Cremades M, Vucicevic K, Bumpus NN, Anton P, Hendrix C, Savic R. PMID: 33547874; PMCID: PMC7965838.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    24. Multidisciplinary sarcoma tumor board: adolescent and young adult soft tissue sarcoma-myxoid liposarcoma and alveolar soft part sarcoma. Chin Clin Oncol. 2020 Oct; 9(5):67. Jayachandran P, Patel D, Hu J, Ragab O, Ho J, Lara K, Ching A, Wayman C, Tseng WW. PMID: 33161723.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    25. Results from a Phase 1 Study of Sodium Selenite in Combination with Palliative Radiation Therapy in Patients with Metastatic Cancer. Transl Oncol. 2019 Nov; 12(11):1525-1531. Knox SJ, Jayachandran P, Keeling CA, Stevens KJ, Sandhu N, Stamps-DeAnda SL, Savic R, Shura L, Buyyounouski MK, Grimes K. PMID: 31454725; PMCID: PMC6717060.
      View in: PubMed   Mentions: 4  
    26. SATB2 and CDX2 are prognostic biomarkers in DNA mismatch repair protein deficient colon cancer. Mod Pathol. 2019 07; 32(8):1217-1231. Ma C, Olevian D, Miller C, Herbst C, Jayachandran P, Kozak MM, Chang DT, Pai RK. PMID: 30962505.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    27. Loss of SATB2 Expression in Colorectal Carcinoma Is Associated With DNA Mismatch Repair Protein Deficiency and BRAF Mutation. Am J Surg Pathol. 2018 10; 42(10):1409-1417. Ma C, Olevian DC, Lowenthal BM, Jayachandran P, Kozak MM, Chang DT, Pai RK. PMID: 30001238.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    28. Immune Reconstitution Inflammatory Syndrome in Patients with AIDS and Disseminated Coccidioidomycosis: A Case Series and Review of the Literature. J Int Assoc Provid AIDS Care. 2017 Nov/Dec; 16(6):540-545. Mu A, Shein TT, Jayachandran P, Paul S. PMID: 28911256.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    29. Repeat Courses of Stereotactic Radiosurgery (SRS), Deferring Whole-Brain Irradiation, for New Brain Metastases After Initial SRS. Int J Radiat Oncol Biol Phys. 2015 Aug 01; 92(5):993-999. Shultz DB, Modlin LA, Jayachandran P, Von Eyben R, Gibbs IC, Choi CYH, Chang SD, Harsh GR, Li G, Adler JR, Hancock SL, Soltys SG. PMID: 26194677.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    30. Smad4 inactivation predicts for worse prognosis and response to fluorouracil-based treatment in colorectal cancer. J Clin Pathol. 2015 May; 68(5):341-5. Kozak MM, von Eyben R, Pai J, Vossler SR, Limaye M, Jayachandran P, Anderson EM, Shaffer JL, Longacre T, Pai RK, Koong AC, Chang DT. PMID: 25681512.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    31. LEF-1 is frequently expressed in colorectal carcinoma and not in other gastrointestinal tract adenocarcinomas: an immunohistochemical survey of 602 gastrointestinal tract neoplasms. Appl Immunohistochem Mol Morphol. 2014 Nov-Dec; 22(10):728-34. Kermanshahi TR, Jayachandran P, Chang DT, Pai R. PMID: 25394300.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    32. BRAF-mutated, microsatellite-stable adenocarcinoma of the proximal colon: an aggressive adenocarcinoma with poor survival, mucinous differentiation, and adverse morphologic features. Am J Surg Pathol. 2012 May; 36(5):744-52. Pai RK, Jayachandran P, Koong AC, Chang DT, Kwok S, Ma L, Arber DA, Balise RR, Tubbs RR, Shadrach B, Pai RK. PMID: 22314188; PMCID: PMC6362986.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansCells
    33. Clinicopathologic and molecular features of sporadic early-onset colorectal adenocarcinoma: an adenocarcinoma with frequent signet ring cell differentiation, rectal and sigmoid involvement, and adverse morphologic features. Mod Pathol. 2012 Aug; 25(8):1128-39. Chang DT, Pai RK, Rybicki LA, Dimaio MA, Limaye M, Jayachandran P, Koong AC, Kunz PA, Fisher GA, Ford JM, Welton M, Shelton A, Ma L, Arber DA, Pai RK. PMID: 22481281.
      View in: PubMed   Mentions: 124     Fields:    Translation:HumansCells
    34. Sex disparities in postoperative outcomes after neurosurgical intervention: findings from the UMEND project. Neurosurgery. 2012 Apr; 70(4):959-64; discussion 964. Davis MC, El-Sayed AM, Ziewacz JE, Jayachandran P, Geisert WC, Zamora-Berridi GJ, Sullivan SE. PMID: 22037314.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    35. Postchemoradiotherapy positron emission tomography predicts pathologic response and survival in patients with esophageal cancer. Int J Radiat Oncol Biol Phys. 2012 Oct 01; 84(2):471-7. Jayachandran P, Pai RK, Quon A, Graves E, Krakow TE, La T, Loo BW, Koong AC, Chang DT. PMID: 22381904.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    36. Postoperative outcomes following closed head injury and craniotomy for evacuation of hematoma in patients older than 80 years. J Neurosurg. 2012 Jan; 116(1):234-45. Lau D, El-Sayed AM, Ziewacz JE, Jayachandran P, Huq FS, Zamora-Berridi GJ, Davis MC, Sullivan SE. PMID: 21888477.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    37. Interfractional uncertainty in the treatment of pancreatic cancer with radiation. Int J Radiat Oncol Biol Phys. 2010 Feb 01; 76(2):603-7. Jayachandran P, Minn AY, Van Dam J, Norton JA, Koong AC, Chang DT. PMID: 19879062.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
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    NIH Funding Acknowledgment: Important - All publications resulting from the utilization of SC CTSI resources are required to credit the SC CTSI grant by including the NIH funding acknowledgment and must comply with the NIH Public Access Policy.

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