Arnold Sipos, MD, PhD

Title(s)Research Assistant Professor of Pathology (Part-Time)
SchoolKeck School of Medicine of Usc
AddressHMR 711
Health Sciences Campus
Los Angeles CA 90089-9099
Phone+1 323 442 2050
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    Collapse Biography 
    Collapse Awards and Honors
    Semmelweis University2001Scientific Award for Medical Students
    Semmelweis University2002Scientific Award for Medical Students
    Hungary2003National Scientific Award for Medical Students
    Semmelweis University Research Council2003Research Grant
    Semmelweis University2003Scientific Award for Medical Students
    European Physiological Societies 2003Travel Grant
    Semmelweis University Research Council2004Scientific Merit
    2007Experimental Biology Travel Grant
    American Heart Association2007  - 2009Postdoctoral Fellowship
    Amgen2008Postdoctoral Excellence in Renal Research Award

    Collapse Overview 
    Collapse Overview
    Dr. Sipos earned his medical degree from Semmelweis University School of Medicine. He then completed his PhD in Pathophysiology. Prior to joining the Division of Pulmonary, Critical Care and Sleep Medicine as an Assistant Professor, Dr. Sipos served as a Postdoctoral Research Associate for the Department of Medicine.

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Real-Time Autophagic Flux Measurements in Live Cells Using a Novel Fluorescent Marker DAPRed. Bio Protoc. 2024 Mar 05; 14(5):e4949. Sipos A, Kim KJ, Alvarez JR, Crandall ED. PMID: 38464942; PMCID: PMC10917693.
      View in: PubMed   Mentions:
    2. Kinetics of autophagic activity in nanoparticle-exposed lung adenocarcinoma (A549) cells. Autophagy Rep. 2023; 2(1). Sipos A, Kim KJ, Sioutas C, Crandall ED. PMID: 37520337; PMCID: PMC10373127.
      View in: PubMed   Mentions: 1  
    3. Biokinetic modeling of nanoparticle interactions with lung alveolar epithelial cells: uptake, intracellular processing, and egress. Am J Physiol Regul Integr Comp Physiol. 2021 01 01; 320(1):R36-R43. Chen W, D'Argenio DZ, Sipos A, Kim KJ, Crandall ED. PMID: 33085912; PMCID: PMC7847057.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    4. Evidence for Nanoparticle-Induced Lysosomal Dysfunction in Lung Adenocarcinoma (A549) Cells. Int J Mol Sci. 2019 Oct 23; 20(21). Sipos A, Kim KJ, Sioutas C, Crandall ED. PMID: 31652767; PMCID: PMC6861930.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    5. Alveolar epithelial cell processing of nanoparticles activates autophagy and lysosomal exocytosis. Am J Physiol Lung Cell Mol Physiol. 2018 08 01; 315(2):L286-L300. Sipos A, Kim KJ, Chow RH, Flodby P, Borok Z, Crandall ED. PMID: 29722567; PMCID: PMC6139662.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    6. The macula densa prorenin receptor is essential in renin release and blood pressure control. Am J Physiol Renal Physiol. 2018 09 01; 315(3):F521-F534. Riquier-Brison ADM, Sipos A, Prókai Á, Vargas SL, Toma L, Meer EJ, Villanueva KG, Chen JCM, Gyarmati G, Yih C, Tang E, Nadim B, Pendekanti S, Garrelds IM, Nguyen G, Danser AHJ, Peti-Peterdi J. PMID: 29667908; PMCID: PMC6172576.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    7. Knockout mice reveal key roles for claudin 18 in alveolar barrier properties and fluid homeostasis. Am J Respir Cell Mol Biol. 2014 Aug; 51(2):210-22. Li G, Flodby P, Luo J, Kage H, Sipos A, Gao D, Ji Y, Beard LL, Marconett CN, DeMaio L, Kim YH, Kim KJ, Laird-Offringa IA, Minoo P, Liebler JM, Zhou B, Crandall ED, Borok Z. PMID: 24588076; PMCID: PMC4148039.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    8. Nanoparticle translocation across mouse alveolar epithelial cell monolayers: species-specific mechanisms. Nanomedicine. 2013 Aug; 9(6):786-94. Fazlollahi F, Kim YH, Sipos A, Hamm-Alvarez SF, Borok Z, Kim KJ, Crandall ED. PMID: 23454523; PMCID: PMC3702651.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    9. Olfactory receptor responding to gut microbiota-derived signals plays a role in renin secretion and blood pressure regulation. Proc Natl Acad Sci U S A. 2013 Mar 12; 110(11):4410-5. Pluznick JL, Protzko RJ, Gevorgyan H, Peterlin Z, Sipos A, Han J, Brunet I, Wan LX, Rey F, Wang T, Firestein SJ, Yanagisawa M, Gordon JI, Eichmann A, Peti-Peterdi J, Caplan MJ. PMID: 23401498; PMCID: PMC3600440.
      View in: PubMed   Mentions: 531     Fields:    Translation:AnimalsCells
    10. A novel dual-color reporter for identifying insulin-producing beta-cells and classifying heterogeneity of insulinoma cell lines. PLoS One. 2012; 7(4):e35521. Lee NS, Rohan JG, Zitting M, Kamath S, Weitz A, Sipos A, Salvaterra PM, Hasegawa K, Pera M, Chow RH. PMID: 22530041; PMCID: PMC3329476.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    11. Translocation of PEGylated quantum dots across rat alveolar epithelial cell monolayers. Int J Nanomedicine. 2011; 6:2849-57. Fazlollahi F, Sipos A, Kim YH, Hamm-Alvarez SF, Borok Z, Kim KJ, Crandall ED. PMID: 22131830; PMCID: PMC3224711.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    12. Nanomaterial interactions with and trafficking across the lung alveolar epithelial barrier: implications for health effects of air-pollution particles. Air Qual Atmos Health. 2011 Mar 01; 4(1):65-78. Yacobi NR, Fazllolahi F, Kim YH, Sipos A, Borok Z, Kim KJ, Crandall ED. PMID: 25568662; PMCID: PMC4283834.
      View in: PubMed   Mentions: 7  
    13. Direct demonstration of tubular fluid flow sensing by macula densa cells. Am J Physiol Renal Physiol. 2010 Nov; 299(5):F1087-93. Sipos A, Vargas S, Peti-Peterdi J. PMID: 20719981; PMCID: PMC2980403.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    14. A high-powered view of the filtration barrier. J Am Soc Nephrol. 2010 Nov; 21(11):1835-41. Peti-Peterdi J, Sipos A. PMID: 20576805; PMCID: PMC4581726.
      View in: PubMed   Mentions: 81     Fields:    Translation:AnimalsCells
    15. Loss of renal microvascular integrity in postnatal Crim1 hypomorphic transgenic mice. Kidney Int. 2009 Dec; 76(11):1161-71. Wilkinson L, Gilbert T, Sipos A, Toma I, Pennisi DJ, Peti-Peterdi J, Little MH. PMID: 19776720.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    16. Connexin 30 deficiency impairs renal tubular ATP release and pressure natriuresis. J Am Soc Nephrol. 2009 Aug; 20(8):1724-32. Sipos A, Vargas SL, Toma I, Hanner F, Willecke K, Peti-Peterdi J. PMID: 19478095; PMCID: PMC2723976.
      View in: PubMed   Mentions: 68     Fields:    Translation:Animals
    17. Multiphoton imaging of renal regulatory mechanisms. Physiology (Bethesda). 2009 Apr; 24:88-96. Peti-Peterdi J, Toma I, Sipos A, Vargas SL. PMID: 19364911; PMCID: PMC4580236.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimals
    18. Succinate receptor GPR91 provides a direct link between high glucose levels and renin release in murine and rabbit kidney. J Clin Invest. 2008 Jul; 118(7):2526-34. Toma I, Kang JJ, Sipos A, Vargas S, Bansal E, Hanner F, Meer E, Peti-Peterdi J. PMID: 18535668; PMCID: PMC2413183.
      View in: PubMed   Mentions: 140     Fields:    Translation:AnimalsCells
    19. Connexin45 is expressed in the juxtaglomerular apparatus and is involved in the regulation of renin secretion and blood pressure. Am J Physiol Regul Integr Comp Physiol. 2008 Aug; 295(2):R371-80. Hanner F, von Maltzahn J, Maxeiner S, Toma I, Sipos A, Krüger O, Willecke K, Peti-Peterdi J. PMID: 18579650; PMCID: PMC2519930.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    20. The collecting duct is the major source of prorenin in diabetes. Hypertension. 2008 Jun; 51(6):1597-604. Kang JJ, Toma I, Sipos A, Meer EJ, Vargas SL, Peti-Peterdi J. PMID: 18413493; PMCID: PMC2398652.
      View in: PubMed   Mentions: 86     Fields:    Translation:AnimalsCells
    21. From in vitro to in vivo: imaging from the single cell to the whole organism. Curr Protoc Cytom. 2008 Apr; Chapter 12:Unit 12.12. Kang JJ, Toma I, Sipos A, Peti-Peterdi J. PMID: 18770644.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    22. Evidence for restriction of fluid and solute movement across the glomerular capillary wall by the subpodocyte space. Am J Physiol Renal Physiol. 2007 Dec; 293(6):F1777-86. Salmon AH, Toma I, Sipos A, Muston PR, Harper SJ, Bates DO, Neal CR, Peti-Peterdi J. PMID: 17804486.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    23. Advances in renal (patho)physiology using multiphoton microscopy. Kidney Int. 2007 Nov; 72(10):1188-91. Sipos A, Toma I, Kang JJ, Rosivall L, Peti-Peterdi J. PMID: 17667980; PMCID: PMC2424113.
      View in: PubMed   Mentions: 28     Fields:    Translation:Animals
    24. Imaging the renin-angiotensin system: an important target of anti-hypertensive therapy. Adv Drug Deliv Rev. 2006 Sep 15; 58(7):824-33. Kang JJ, Toma I, Sipos A, McCulloch F, Peti-Peterdi J. PMID: 16979787.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    25. Fluid flow in the juxtaglomerular interstitium visualized in vivo. Am J Physiol Renal Physiol. 2006 Dec; 291(6):F1241-7. Rosivall L, Mirzahosseini S, Toma I, Sipos A, Peti-Peterdi J. PMID: 16868308.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    26. Quantitative imaging of basic functions in renal (patho)physiology. Am J Physiol Renal Physiol. 2006 Aug; 291(2):F495-502. Kang JJ, Toma I, Sipos A, McCulloch F, Peti-Peterdi J. PMID: 16609147.
      View in: PubMed   Mentions: 87     Fields:    Translation:Animals
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    NIH Funding Acknowledgment: Important - All publications resulting from the utilization of SC CTSI resources are required to credit the SC CTSI grant by including the NIH funding acknowledgment and must comply with the NIH Public Access Policy.

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