Alicia A. McDonough, PhD, FAHA

Title(s)Professor of Physiology and Neuroscience
AddressZNI 101, 1501 San Pablo Street
Health Sciences Campus
Los Angeles CA 90089
Phone+1 323 442 1238
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    Collapse Biography 
    Collapse Awards and Honors
    International Union of Physiological Scientists2022Robert Pitt Awardee
    Case Western School of Medicine2019Ulrich Hopfer Lectureship
    American Physiological Society Epithelial Transport Group2018Steve Hebert Lecturer
    University of Southern California2018Phi Kappa Phi Faculty Recognition Award
    American Society of Nephrology2017Robert W. Schrier Endowed Lectureship
    Medical College of Wisconsin2016J.J. Smith Endowed Lecture
    KCVD Young Investigator Symposium2016Keynote Speaker ASN Kidney Week
    Kansas State Univ. Veterinary Medicine2015Clarenberg Distinguished Lecture
    AHA Kidney in Cardiovascular Disease Council2014Donald Seldin Lecture
    SUNY Buffalo2010Suk Ki Hong Memorial Lecturer
    American Physiological Society2009Ernest H. Starling Distinguished Lectureship
    American Heart Association1984  - 1989Established Investigator Award
    Keck School of Medicine2007  - 2018Outstanding Teaching Awards: '07, '12, '17

    Collapse Research 
    Collapse Research Activities and Funding
    Renal sodium handling in hypertension: impact of age, sex, and dietary potassium
    NIH R56DK123780Sep 14, 2020 - Aug 31, 2021
    Role: Principal Investigator
    Development of a new method for estimating potassium fluxes in vivo using stable potassium isotope ratios
    University Kidney Research Organization UKRO - PilotJun 1, 2019 - May 31, 2020
    Role: Co-Investigator
    Role Description: Conduct experiments in rats to assess potassium fluxes.
    The interleukin-1 receptor regulates crosstalk between myeloid and renal tubular cells in hypertension
    NIH R01DK118019Mar 1, 2019 - Feb 28, 2023
    Role: Co-Investigator
    Impact of Diabetes on Renal Transporters in females and males
    NIH - DIACOMP (diabetes complications) U24 DK115255Mar 1, 2019 - Mar 1, 2020
    Role: PI - subcontract from DIACOMP
    Sodium transporter regulation during hypertension
    NIH R01DK083785Apr 1, 2009 - Apr 30, 2015
    Role: Principal Investigator
    Regulation of Na-CI cotransporter (NCC) subcellular distribution in DCT
    NIH R21HL085388Aug 1, 2006 - Jul 31, 2009
    Role: Principal Investigator
    NIH R01DK057678May 1, 2001 - Mar 31, 2005
    Role: Principal Investigator
    Regulation of Sodium Transport in the Kidney
    NIH R01DK034316Jul 1, 1984 - Sep 30, 1987
    Role: Principal Investigator
    NIH R01AM034316Jul 1, 1984 - Jun 30, 1987
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse In The News
    Collapse Featured Presentations
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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Coordinate adaptations of skeletal muscle and kidney to maintain extracellular [K+] during K+-deficient diet. Am J Physiol Cell Physiol. 2020 10 01; 319(4):C757-C770. McFarlin BE, Chen Y, Priver TS, Ralph DL, Mercado A, Gamba G, Madhur MS, McDonough AA. PMID: 32845718.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. Sex differences in solute transport along the nephrons: effects of Na+ transport inhibition. Am J Physiol Renal Physiol. 2020 09 01; 319(3):F487-F505. Hu R, McDonough AA, Layton AT. PMID: 32744084.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    3. a2A-Adrenoceptors Modulate Renal Sympathetic Neurotransmission and Protect against Hypertensive Kidney Disease. J Am Soc Nephrol. 2020 04; 31(4):783-798. Hering L, Rahman M, Hoch H, Markó L, Yang G, Reil A, Yakoub M, Gupta V, Potthoff SA, Vonend O, Ralph DL, Gurley SB, McDonough AA, Rump LC, Stegbauer J. PMID: 32086277.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    4. Report of the National Heart, Lung, and Blood Institute Working Group on Hypertension: Barriers to Translation. Hypertension. 2020 Apr; 75(4):902-917. Sigmund CD, Carey RM, Appel LJ, Arnett DK, Bosworth HB, Cushman WC, Galis ZS, Green Parker M, Hall JE, Harrison DG, McDonough AA, Nicastro HL, Oparil S, Osborn JW, Raizada MK, Wright JD, Oh YS. PMID: 32063061.
      View in: PubMed   Mentions: 1     Fields:    
    5. Electrolyte and transporter responses to angiotensin II induced hypertension in female and male rats and mice. Acta Physiol (Oxf). 2020 05; 229(1):e13448. Veiras LC, McFarlin BE, Ralph DL, Buncha V, Prescott J, Shirvani BS, McDonough JC, Ha D, Giani J, Gurley SB, Mamenko M, McDonough AA. PMID: 31994810.
      View in: PubMed   Mentions: 3     Fields:    
    6. Impact of angiotensin II-mediated stimulation of sodium transporters in the nephron assessed by computational modeling. Am J Physiol Renal Physiol. 2019 12 01; 317(6):F1656-F1668. Edwards A, McDonough AA. PMID: 31657247.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    7. Functional implications of the sex differences in transporter abundance along the rat nephron: modeling and analysis. Am J Physiol Renal Physiol. 2019 12 01; 317(6):F1462-F1474. Hu R, McDonough AA, Layton AT. PMID: 31566436.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    8. The Absence of the ACE N-Domain Decreases Renal Inflammation and Facilitates Sodium Excretion during Diabetic Kidney Disease. J Am Soc Nephrol. 2018 10; 29(10):2546-2561. Eriguchi M, Bernstein EA, Veiras LC, Khan Z, Cao DY, Fuchs S, McDonough AA, Toblli JE, Gonzalez-Villalobos RA, Bernstein KE, Giani JF. PMID: 30185469.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    9. Functional implications of sexual dimorphism of transporter patterns along the rat proximal tubule: modeling and analysis. Am J Physiol Renal Physiol. 2018 09 01; 315(3):F692-F700. Li Q, McDonough AA, Layton HE, Layton AT. PMID: 29846110.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    10. Downregulation of the Cl-/HCO3-Exchanger Pendrin in Kidneys of Mice with Cystic Fibrosis: Role in the Pathogenesis of Metabolic Alkalosis. Cell Physiol Biochem. 2018; 45(4):1551-1565. Varasteh Kia M, Barone S, McDonough AA, Zahedi K, Xu J, Soleimani M. PMID: 29482189.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    11. Blood pressure regulation by the angiotensin type 1 receptor in the proximal tubule. Curr Opin Nephrol Hypertens. 2018 01; 27(1):1-7. van Haaster MC, McDonough AA, Gurley SB. PMID: 29045337.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    12. Collecting Duct Nitric Oxide Synthase 1ß Activation Maintains Sodium Homeostasis During High Sodium Intake Through Suppression of Aldosterone and Renal Angiotensin II Pathways. J Am Heart Assoc. 2017 Oct 24; 6(10). Hyndman KA, Mironova EV, Giani JF, Dugas C, Collins J, McDonough AA, Stockand JD, Pollock JS. PMID: 29066445.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    13. Collecting duct prorenin receptor knockout reduces renal function, increases sodium excretion, and mitigates renal responses in ANG II-induced hypertensive mice. Am J Physiol Renal Physiol. 2017 Dec 01; 313(6):F1243-F1253. Prieto MC, Reverte V, Mamenko M, Kuczeriszka M, Veiras LC, Rosales CB, McLellan M, Gentile O, Jensen VB, Ichihara A, McDonough AA, Pochynyuk OM, Gonzalez AA. PMID: 28814438.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    14. Sexual Dimorphic Pattern of Renal Transporters and Electrolyte Homeostasis. J Am Soc Nephrol. 2017 Dec; 28(12):3504-3517. Veiras LC, Girardi ACC, Curry J, Pei L, Ralph DL, Tran A, Castelo-Branco RC, Pastor-Soler N, Arranz CT, Yu ASL, McDonough AA. PMID: 28774999.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    15. Potassium Homeostasis: The Knowns, the Unknowns, and the Health Benefits. Physiology (Bethesda). 2017 03; 32(2):100-111. McDonough AA, Youn JH. PMID: 28202621.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    16. Cardiovascular benefits associated with higher dietary K+ vs. lower dietary Na+: evidence from population and mechanistic studies. Am J Physiol Endocrinol Metab. 2017 04 01; 312(4):E348-E356. McDonough AA, Veiras LC, Guevara CA, Ralph DL. PMID: 28174181.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    17. Renal Collectrin Protects against Salt-Sensitive Hypertension and Is Downregulated by Angiotensin II. J Am Soc Nephrol. 2017 Jun; 28(6):1826-1837. Chu PL, Gigliotti JC, Cechova S, Bodonyi-Kovacs G, Chan F, Ralph DL, Howell N, Kalantari K, Klibanov AL, Carey RM, McDonough AA, Le TH. PMID: 28062568.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    18. Renal tubular angiotensin converting enzyme is responsible for nitro-L-arginine methyl ester (L-NAME)-induced salt sensitivity. Kidney Int. 2017 04; 91(4):856-867. Giani JF, Eriguchi M, Bernstein EA, Katsumata M, Shen XZ, Li L, McDonough AA, Fuchs S, Bernstein KE, Gonzalez-Villalobos RA. PMID: 27988209.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    19. Potassium Supplementation Prevents Sodium Chloride Cotransporter Stimulation During Angiotensin II Hypertension. Hypertension. 2016 10; 68(4):904-12. Veiras LC, Han J, Ralph DL, McDonough AA. PMID: 27600183.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    20. ISN Forefronts Symposium 2015: Maintaining Balance Under Pressure-Hypertension and the Proximal Tubule. Kidney Int Rep. 2016 Sep; 1(3):166-176. McDonough AA. PMID: 27840855.
      View in: PubMed   Mentions:
    21. Paracellular epithelial sodium transport maximizes energy efficiency in the kidney. J Clin Invest. 2016 07 01; 126(7):2509-18. Pei L, Solis G, Nguyen MT, Kamat N, Magenheimer L, Zhuo M, Li J, Curry J, McDonough AA, Fields TA, Welch WJ, Yu AS. PMID: 27214555.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    22. Interleukin-17A Regulates Renal Sodium Transporters and Renal Injury in Angiotensin II-Induced Hypertension. Hypertension. 2016 07; 68(1):167-74. Norlander AE, Saleh MA, Kamat NV, Ko B, Gnecco J, Zhu L, Dale BL, Iwakura Y, Hoover RS, McDonough AA, Madhur MS. PMID: 27141060.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    23. Interleukin-1 Receptor Activation Potentiates Salt Reabsorption in Angiotensin II-Induced Hypertension via the NKCC2 Co-transporter in the Nephron. Cell Metab. 2016 Feb 09; 23(2):360-8. Zhang J, Rudemiller NP, Patel MB, Karlovich NS, Wu M, McDonough AA, Griffiths R, Sparks MA, Jeffs AD, Crowley SD. PMID: 26712462.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    24. The physiological role of glucagon-like peptide-1 in the regulation of renal function. Am J Physiol Renal Physiol. 2016 Jan 15; 310(2):F123-7. Farah LX, Valentini V, Pessoa TD, Malnic G, McDonough AA, Girardi AC. PMID: 26447224.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    25. Short-term nonpressor angiotensin II infusion stimulates sodium transporters in proximal tubule and distal nephron. Physiol Rep. 2015 Sep; 3(9). Nguyen MT, Han J, Ralph DL, Veiras LC, McDonough AA. PMID: 26347505.
      View in: PubMed   Mentions: 14     Fields:    
    26. Proximal tubule NHE3 activity is inhibited by beta-arrestin-biased angiotensin II type 1 receptor signaling. . 2015 Oct 15; 309(8):C541-50. Carneiro de Morais CP, Polidoro JZ, Ralph DL, Pessoa TD, Oliveira-Souza M, Barauna VG, Rebouças NA, Malnic G, McDonough AA, Girardi AC. PMID: 26246427.
      View in: PubMed   Mentions:
    27. Salt Sensitivity in Response to Renal Injury Requires Renal Angiotensin-Converting Enzyme. Hypertension. 2015 Sep; 66(3):534-42. Giani JF, Bernstein KE, Janjulia T, Han J, Toblli JE, Shen XZ, Rodriguez-Iturbe B, McDonough AA, Gonzalez-Villalobos RA. PMID: 26150439.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    28. Maintaining Balance Under Pressure: Integrated Regulation of Renal Transporters During Hypertension. Hypertension. 2015 Sep; 66(3):450-5. McDonough AA, Nguyen MT. PMID: 26101347.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    29. Renal NCC is unchanged in the midpregnant rat and decreased in the late pregnant rat despite avid renal Na+ retention. Am J Physiol Renal Physiol. 2015 Jul 01; 309(1):F63-70. West CA, McDonough AA, Masilamani SM, Verlander JW, Baylis C. PMID: 25925254.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    30. The intrarenal generation of angiotensin II is required for experimental hypertension. Curr Opin Pharmacol. 2015 Apr; 21:73-81. Giani JF, Shah KH, Khan Z, Bernstein EA, Shen XZ, McDonough AA, Gonzalez-Villalobos RA, Bernstein KE. PMID: 25616034.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    31. Renal transporter activation during angiotensin-II hypertension is blunted in interferon-?-/- and interleukin-17A-/- mice. Hypertension. 2015 Mar; 65(3):569-76. Kamat NV, Thabet SR, Xiao L, Saleh MA, Kirabo A, Madhur MS, Delpire E, Harrison DG, McDonough AA. PMID: 25601932.
      View in: PubMed   Mentions: 66     Fields:    Translation:Animals
    32. Considerations when quantitating protein abundance by immunoblot. . 2015 Mar 15; 308(6):C426-33. McDonough AA, Veiras LC, Minas JN, Ralph DL. PMID: 25540176.
      View in: PubMed   Mentions:
    33. Paradoxical activation of the sodium chloride cotransporter (NCC) without hypertension in kidney deficient in a regulatory subunit of Na,K-ATPase, FXYD2. Physiol Rep. 2014 Dec 01; 2(12). Arystarkhova E, Ralph DL, Liu YB, Bouley R, McDonough AA, Sweadner KJ. PMID: 25472608.
      View in: PubMed   Mentions: 3     Fields:    
    34. Local pH domains regulate NHE3-mediated Na? reabsorption in the renal proximal tubule. Am J Physiol Renal Physiol. 2014 Dec 01; 307(11):F1249-62. Brasen JC, Burford JL, McDonough AA, Holstein-Rathlou NH, Peti-Peterdi J. PMID: 25298526.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    35. Renal generation of angiotensin II and the pathogenesis of hypertension. Curr Hypertens Rep. 2014 Sep; 16(9):477. Giani JF, Janjulia T, Taylor B, Bernstein EA, Shah K, Shen XZ, McDonough AA, Bernstein KE, Gonzalez-Villalobos RA. PMID: 25097114.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    36. Of mice and men: modeling cardiovascular complexity in diabetes. Focus on "Mitochondrial inefficiencies and anoxic ATP hydrolysis capacities in diabetic rat heart". . 2014 Sep 15; 307(6):C497-8. Patel HH, McDonough AA. PMID: 25031018.
      View in: PubMed   Mentions:
    37. Renal angiotensin-converting enzyme is essential for the hypertension induced by nitric oxide synthesis inhibition. J Am Soc Nephrol. 2014 Dec; 25(12):2752-63. Giani JF, Janjulia T, Kamat N, Seth DM, Blackwell WL, Shah KH, Shen XZ, Fuchs S, Delpire E, Toblli JE, Bernstein KE, McDonough AA, Gonzalez-Villalobos RA. PMID: 25012170.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    38. Increasing plasma [K+] by intravenous potassium infusion reduces NCC phosphorylation and drives kaliuresis and natriuresis. Am J Physiol Renal Physiol. 2014 May 01; 306(9):F1059-68. Rengarajan S, Lee DH, Oh YT, Delpire E, Youn JH, McDonough AA. PMID: 24598799.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    39. Compression injury in the mouse spinal cord elicits a specific proliferative response and distinct cell fate acquisition along rostro-caudal and dorso-ventral axes. Neuroscience. 2013 Dec 19; 254:1-17. McDonough A, Hoang AN, Monterrubio AM, Greenhalgh S, Martínez-Cerdeño V. PMID: 24042034.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    40. Differential regulation of Na+ transporters along nephron during ANG II-dependent hypertension: distal stimulation counteracted by proximal inhibition. Am J Physiol Renal Physiol. 2013 Aug 15; 305(4):F510-9. Nguyen MT, Lee DH, Delpire E, McDonough AA. PMID: 23720346.
      View in: PubMed   Mentions: 44     Fields:    Translation:Animals
    41. Need to quickly excrete K(+)? Turn off NCC. Kidney Int. 2013 May; 83(5):779-82. McDonough AA, Youn JH. PMID: 23633048.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    42. The absence of intrarenal ACE protects against hypertension. J Clin Invest. 2013 May; 123(5):2011-23. Gonzalez-Villalobos RA, Janjoulia T, Fletcher NK, Giani JF, Nguyen MT, Riquier-Brison AD, Seth DM, Fuchs S, Eladari D, Picard N, Bachmann S, Delpire E, Peti-Peterdi J, Navar LG, Bernstein KE, McDonough AA. PMID: 23619363.
      View in: PubMed   Mentions: 91     Fields:    Translation:Animals
    43. Proximal tubule specific knockout of the Na?/H? exchanger NHE3: effects on bicarbonate absorption and ammonium excretion. J Mol Med (Berl). 2013 Aug; 91(8):951-63. Li HC, Du Z, Barone S, Rubera I, McDonough AA, Tauc M, Zahedi K, Wang T, Soleimani M. PMID: 23508938.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    44. Effects of ACE inhibition and ANG II stimulation on renal Na-Cl cotransporter distribution, phosphorylation, and membrane complex properties. . 2013 Jan 15; 304(2):C147-63. Lee DH, Maunsbach AB, Riquier-Brison AD, Nguyen MT, Fenton RA, Bachmann S, Yu AS, McDonough AA. PMID: 23114965.
      View in: PubMed   Mentions:
    45. How does potassium supplementation lower blood pressure? Am J Physiol Renal Physiol. 2012 May 01; 302(9):F1224-5. McDonough AA, Nguyen MT. PMID: 22550158.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    46. Effects of K+-deficient diets with and without NaCl supplementation on Na+, K+, and H2O transporters' abundance along the nephron. Am J Physiol Renal Physiol. 2012 Jul 01; 303(1):F92-104. Nguyen MT, Yang LE, Fletcher NK, Lee DH, Kocinsky H, Bachmann S, Delpire E, McDonough AA. PMID: 22496411.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    47. Transport, cilia, and PKD: must we in (cyst) on interrelationships? Focus on "Increased Na+/H+ exchanger activity on the apical surface of a cilium-deficient cortical collecting duct principal cell model of polycystic kidney disease". . 2012 May 15; 302(10):C1434-5. Avner ED, McDonough AA, Sweeney WE. PMID: 22403786.
      View in: PubMed   Mentions:
    48. AT1A angiotensin receptors in the renal proximal tubule regulate blood pressure. Cell Metab. 2011 Apr 06; 13(4):469-475. Gurley SB, Riquier-Brison ADM, Schnermann J, Sparks MA, Allen AM, Haase VH, Snouwaert JN, Le TH, McDonough AA, Koller BH, Coffman TM. PMID: 21459331.
      View in: PubMed   Mentions: 97     Fields:    Translation:AnimalsCells
    49. Mechanisms of proximal tubule sodium transport regulation that link extracellular fluid volume and blood pressure. . 2010 Apr; 298(4):R851-61. McDonough AA. PMID: 20106993.
      View in: PubMed   Mentions:
    50. Angiotensin II stimulates trafficking of NHE3, NaPi2, and associated proteins into the proximal tubule microvilli. Am J Physiol Renal Physiol. 2010 Jan; 298(1):F177-86. Riquier-Brison AD, Leong PK, Pihakaski-Maunsbach K, McDonough AA. PMID: 19864301.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    51. Motoring down the microvilli. Focus on "PTH-induced internalization of apical membrane NaPi2a: role of actin and myosin VI". . 2009 Dec; 297(6):C1331-2. McDonough AA. PMID: 19776391.
      View in: PubMed   Mentions:
    52. Isoform specificity of cardiac glycosides binding to human Na+,K+-ATPase alpha1beta1, alpha2beta1 and alpha3beta1. Eur J Pharmacol. 2009 Nov 10; 622(1-3):7-14. Hauck C, Potter T, Bartz M, Wittwer T, Wahlers T, Mehlhorn U, Scheiner-Bobis G, McDonough AA, Bloch W, Schwinger RH, Müller-Ehmsen J. PMID: 19751721.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    53. Narrative review: evolving concepts in potassium homeostasis and hypokalemia. Ann Intern Med. 2009 May 05; 150(9):619-25. Greenlee M, Wingo CS, McDonough AA, Youn JH, Kone BC. PMID: 19414841.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    54. Renal NHE3 and NaPi2 partition into distinct membrane domains. . 2009 Apr; 296(4):C900-10. Riquier AD, Lee DH, McDonough AA. PMID: 19158399.
      View in: PubMed   Mentions:
    55. Acute hypertension provokes acute trafficking of distal tubule Na-Cl cotransporter (NCC) to subapical cytoplasmic vesicles. Am J Physiol Renal Physiol. 2009 Apr; 296(4):F810-8. Lee DH, Riquier AD, Yang LE, Leong PK, Maunsbach AB, McDonough AA. PMID: 19144688.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    56. Recent advances in understanding integrative control of potassium homeostasis. Annu Rev Physiol. 2009; 71:381-401. Youn JH, McDonough AA. PMID: 18759636.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimals
    57. Rationale and design of CAPITA: a RCT of 13-valent conjugated pneumococcal vaccine efficacy among older adults. Neth J Med. 2008 Oct; 66(9):378-83. Hak E, Grobbee DE, Sanders EA, Verheij TJ, Bolkenbaas M, Huijts SM, Gruber WC, Tansey S, McDonough A, Thoma B, Patterson S, van Alphen AJ, Bonten MJ. PMID: 18990781.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
    58. Effects of dietary salt on renal Na+ transporter subcellular distribution, abundance, and phosphorylation status. Am J Physiol Renal Physiol. 2008 Oct; 295(4):F1003-16. Yang LE, Sandberg MB, Can AD, Pihakaski-Maunsbach K, McDonough AA. PMID: 18653479.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    59. Connexin 30.3 is expressed in the kidney but not regulated by dietary salt or high blood pressure. Cell Commun Adhes. 2008 May; 15(1):219-30. Hanner F, Schnichels M, Zheng-Fischhöfer Q, Yang LE, Toma I, Willecke K, McDonough AA, Peti-Peterdi J. PMID: 18649192.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    60. Slc26a6 (PAT1) deletion downregulates the apical Na+/H+ exchanger in the straight segment of the proximal tubule. Am J Nephrol. 2008; 28(2):330-8. Petrovic S, Barone S, Wang Z, McDonough AA, Amlal H, Soleimani M. PMID: 18046080.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    61. AMPK activation with AICAR provokes an acute fall in plasma [K+]. . 2008 Jan; 294(1):C126-35. Zheng D, Perianayagam A, Lee DH, Brannan MD, Yang LE, Tellalian D, Chen P, Lemieux K, Marette A, Youn JH, McDonough AA. PMID: 18003746.
      View in: PubMed   Mentions:
    62. Reducing blood pressure in SHR with enalapril provokes redistribution of NHE3, NaPi2, and NCC and decreases NaPi2 and ACE abundance. Am J Physiol Renal Physiol. 2007 Oct; 293(4):F1197-208. Yang LE, Leong PK, McDonough AA. PMID: 17652375.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    63. Evidence for gut factor in K+ homeostasis. Am J Physiol Renal Physiol. 2007 Aug; 293(2):F541-7. Lee FN, Oh G, McDonough AA, Youn JH. PMID: 17522262.
      View in: PubMed   Mentions: 26     Fields:    Translation:Animals
    64. ANG II provokes acute trafficking of distal tubule Na+-Cl(-) cotransporter to apical membrane. Am J Physiol Renal Physiol. 2007 Sep; 293(3):F662-9. Sandberg MB, Riquier AD, Pihakaski-Maunsbach K, McDonough AA, Maunsbach AB. PMID: 17507603.
      View in: PubMed   Mentions: 74     Fields:    Translation:Animals
    65. The proximal convoluted tubule is a target for the uroguanylin-regulated natriuretic response. J Pediatr Gastroenterol Nutr. 2006 Jul; 43 Suppl 1:S74-81. Elitsur N, Lorenz JN, Hawkins JA, Rudolph JA, Witte D, Yang LE, McDonough AA, Cohen MB. PMID: 16819406.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    66. Redistribution of distal tubule Na+-Cl- cotransporter (NCC) in response to a high-salt diet. Am J Physiol Renal Physiol. 2006 Aug; 291(2):F503-8. Sandberg MB, Maunsbach AB, McDonough AA. PMID: 16554416.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
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