Alicia A. McDonough, PhD, FAHA

Title(s)Professor of Physiology and Neuroscience
SchoolKeck School of Medicine of Usc
AddressZNI 101, 1501 San Pablo Street
Health Sciences Campus
Los Angeles CA 90089
Phone+1 323 442 1238
vCardDownload vCard

    Collapse Biography 
    Collapse Awards and Honors
    American Heart Association Hypertension Council2022 Irvine Page & Alba Bradley Lifetime Achievement Award
    International Union of Physiological Scientists2022Robert Pitts Awardee
    Case Western School of Medicine2019Ulrich Hopfer Lectureship
    American Physiological Society Epithelial Transport Group2018Steve Hebert Lecturer
    University of Southern California2018Phi Kappa Phi Faculty Recognition Award
    American Society of Nephrology2017Robert W. Schrier Endowed Lectureship
    Medical College of Wisconsin2016J.J. Smith Endowed Lecture
    American Heart Association KCVD Young Investigator Symposium2016Keynote Speaker ASN Kidney Week
    Kansas State Univ. Veterinary Medicine2015Clarenberg Distinguished Lecture
    American Heart Association Kidney in Cardiovascular Disease Council2014Donald Seldin Lecture
    SUNY Buffalo2010Suk Ki Hong Memorial Lecturer
    American Physiological Society2009Ernest H. Starling Distinguished Lectureship
    Keck School of Medicine2007  - 2018Outstanding Teaching Awards: '07, '12, '17
    American Heart Association1984  - 1989Established Investigator Award

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Renal electrolyte handling in females vs. males over life cycle
    NIH 2R01DK083785-10A1Aug 29, 2022 - May 31, 2027
    Role: PI
    Description: The blood pressure set point is determined by the kidney, and disruption of kidney function can provoke hypertension, the leading cause of premature death in the developed world. This MPI project aims to advance our understanding of how nephrons adjust operation over life cycle as a function of sex and age (in order to maintain homeostasis and blood pressure), and how kidney function adapts in response to challenges including lactation, menopause, loss/donation of one kidney, and dietary salt. We propose to combine experimental measurements in rats with computational modeling to determine how age- and sex- based differences in kidney fluid and electrolyte handling impact blood pressure regulation (which can guide the appropriate choice of anti-hypertensive therapeutic targets) as a function of sex and stage in life cycle.
    Renal sodium handling in hypertension: impact of age, sex, and dietary potassium
    NIH R56DK123780Sep 14, 2020 - Aug 31, 2021
    Role: Principal Investigator
    Development of a new method for estimating potassium fluxes in vivo using stable potassium isotope ratios
    University Kidney Research Organization UKRO - PilotJun 1, 2019 - May 31, 2020
    Role: Co-Investigator
    Description: Conduct experiments in rats to assess potassium fluxes.
    The interleukin-1 receptor regulates crosstalk between myeloid and renal tubular cells in hypertension
    NIH R01DK118019Mar 1, 2019 - Feb 28, 2023
    Role: Co-Investigator
    Impact of Diabetes on Renal Transporters in females and males
    NIH - DIACOMP (diabetes complications) U24 DK115255Mar 1, 2019 - Mar 1, 2020
    Role: PI - subcontract from DIACOMP
    Sodium transporter regulation during hypertension
    NIH R01DK083785Apr 1, 2009 - Mar 31, 2021
    Role: Principal Investigator
    Regulation of Na-CI cotransporter (NCC) subcellular distribution in DCT
    NIH R21HL085388Aug 1, 2006 - Jul 31, 2009
    Role: Principal Investigator
    EXTRA-RENAL REGULATION OF POTASSIUM HOMEOSTASIS
    NIH R01DK057678May 1, 2001 - Feb 28, 2006
    Role: Principal Investigator
    Regulation of Sodium Transport in the Kidney
    NIH R01DK034316Jul 1, 1984 - Mar 31, 2010
    Role: Principal Investigator
    REGULATION OF SODIUM PUMPS IN THE KIDNEY
    NIH R01AM034316Jul 1, 1984 - Jun 30, 1987
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Faculty Mentoring

    Collapse Featured Content 
    Collapse Featured Videos

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Kinetic Modeling of In Vivo K+ Distribution and Fluxes with Stable K+ Isotopes: Effects of Dietary K+ Restriction. Int J Mol Sci. 2024 Sep 06; 25(17). Youn JH, Gili S, Oh Y, McDonough AA, Higgins J. PMID: 39273611; PMCID: PMC11395305.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    2. Optimizing renal transporter immunodetection: consequences of freeze-thaw during sample preparation. Am J Physiol Renal Physiol. 2024 Oct 01; 327(4):F655-F666. Hartman-Houstman HL, Ralph DL, Nelson JW, Palmer LG, Faulkner JE, Sullivan JC, Moronge DM, McDonough AA. PMID: 39205660; PMCID: PMC11483075.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    3. Potassium-Alkali-Enriched Diet, Hypertension, and Proteinuria following Uninephrectomy. J Am Soc Nephrol. 2024 Oct 01; 35(10):1330-1350. Ralph DL, Ha D, Lei H, Priver TS, Smith SD, McFarlin BE, Schwindt S, Pandya D, Koepsell H, Pastor-Soler NM, Edwards A, McDonough AA. PMID: 38913441; PMCID: PMC11452139.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    4. Angiotensin II Directly Increases Endothelial Calcium and Nitric Oxide in Kidney and Brain Microvessels In Vivo With Reduced Efficacy in Hypertension. J Am Heart Assoc. 2024 May 21; 13(10):e033998. Becerra Calderon A, Shroff UN, Deepak S, Izuhara A, Trogen G, McDonough AA, Gurley SB, Nelson JW, Peti-Peterdi J, Gyarmati G. PMID: 38726925; PMCID: PMC11179802.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    5. Our Editorial Fellowship Program: Building Synergism. J Am Soc Nephrol. 2023 12 01; 34(12):1940-1943. Gyarmati G, McDonough AA. PMID: 37902620; PMCID: PMC10703069.
      View in: PubMed   Mentions: 1     Fields:    
    6. Angiotensin II hypertension along the female rat tubule: predicted impact on coupled transport of Na+ and K. Am J Physiol Renal Physiol. 2023 12 01; 325(6):F733-F749. Edwards A, Ralph DL, Mercado A, McDonough AA. PMID: 37823196; PMCID: PMC10878725.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    7. Sex differences in renal transporters: assessment and functional consequences. Nat Rev Nephrol. 2024 01; 20(1):21-36. McDonough AA, Harris AN, Xiong LI, Layton AT. PMID: 37684523; PMCID: PMC11090267.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    8. Sex differences in renal electrolyte transport. Curr Opin Nephrol Hypertens. 2023 09 01; 32(5):467-475. McDonough AA, Layton AT. PMID: 37382185; PMCID: PMC10526720.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    9. Stable potassium isotopes (41K/39K) track transcellular and paracellular potassium transport in biological systems. Front Physiol. 2022; 13:1016242. Higgins JA, Ramos DS, Gili S, Spetea C, Kanoski S, Ha D, McDonough AA, Youn JH. PMID: 36388124; PMCID: PMC9644202.
      View in: PubMed   Mentions: 2  
    10. Cell-Specific Actions of the Prostaglandin E-Prostanoid Receptor 4 Attenuating Hypertension: A Dominant Role for Kidney Epithelial Cells Compared With Macrophages. J Am Heart Assoc. 2022 10 04; 11(19):e026581. Yang T, Song C, Ralph DL, Andrews P, Sparks MA, Koller BH, McDonough AA, Coffman TM. PMID: 36172956; PMCID: PMC9673718.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    11. The Highs and Lows of Potassium Intake in CKD-Does One Size Fit All? J Am Soc Nephrol. 2022 09; 33(9):1638-1640. Terker AS, Saritas T, McDonough AA. PMID: 36630492; PMCID: PMC9529180.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    12. Potassium homeostasis: sensors, mediators, and targets. Pflugers Arch. 2022 08; 474(8):853-867. McDonough AA, Fenton RA. PMID: 35727363; PMCID: PMC10163916.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    13. Estimating in vivo potassium distribution and fluxes with stable potassium isotopes. Am J Physiol Cell Physiol. 2022 03 01; 322(3):C410-C420. Youn JH, Oh YT, Gili S, McDonough AA, Higgins J. PMID: 35080924; PMCID: PMC8917925.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    14. Sex-specific adaptations to high-salt diet preserve electrolyte homeostasis with distinct sodium transporter profiles. Am J Physiol Cell Physiol. 2021 11 01; 321(5):C897-C909. Torres-Pinzon DL, Ralph DL, Veiras LC, McDonough AA. PMID: 34613843; PMCID: PMC8616593.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    15. Local and downstream actions of proximal tubule angiotensin II signaling on Na+ transporters in the mouse nephron. Am J Physiol Renal Physiol. 2021 07 01; 321(1):F69-F81. Nelson JW, McDonough AA, Xiang Z, Ralph DL, Robertson JA, Giani JF, Bernstein KE, Gurley SB. PMID: 34056928; PMCID: PMC8321806.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    16. Sex differences in solute and water handling in the human kidney: Modeling and functional implications. iScience. 2021 Jun 25; 24(6):102667. Hu R, McDonough AA, Layton AT. PMID: 34169242; PMCID: PMC8209279.
      View in: PubMed   Mentions: 18  
    17. Vascular control of kidney epithelial transporters. Am J Physiol Renal Physiol. 2021 06 01; 320(6):F1080-F1092. Sparks MA, Dilmen E, Ralph DL, Rianto F, Hoang TA, Hollis A, Diaz EJ, Adhikari R, Chew G, Petretto EG, Gurley SB, McDonough AA, Coffman TM. PMID: 33969697; PMCID: PMC8285646.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    18. Impact of casein- versus grain-based diets on rat renal sodium transporters' abundance and regulation. Kidney360. 2021 03; 2(3):519-523. McDonough AA, Veiras LC, McFarlin BE, Ralph DL. PMID: 34095853; PMCID: PMC8174819.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    19. Coordinate adaptations of skeletal muscle and kidney to maintain extracellular [K+] during K+-deficient diet. Am J Physiol Cell Physiol. 2020 10 01; 319(4):C757-C770. McFarlin BE, Chen Y, Priver TS, Ralph DL, Mercado A, Gamba G, Madhur MS, McDonough AA. PMID: 32845718; PMCID: PMC7654654.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    20. Sex differences in solute transport along the nephrons: effects of Na+ transport inhibition. Am J Physiol Renal Physiol. 2020 09 01; 319(3):F487-F505. Hu R, McDonough AA, Layton AT. PMID: 32744084; PMCID: PMC7509281.
      View in: PubMed   Mentions: 26     Fields:    Translation:Animals
    21. α2A-Adrenoceptors Modulate Renal Sympathetic Neurotransmission and Protect against Hypertensive Kidney Disease. J Am Soc Nephrol. 2020 04; 31(4):783-798. Hering L, Rahman M, Hoch H, Markó L, Yang G, Reil A, Yakoub M, Gupta V, Potthoff SA, Vonend O, Ralph DL, Gurley SB, McDonough AA, Rump LC, Stegbauer J. PMID: 32086277; PMCID: PMC7191918.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    22. Report of the National Heart, Lung, and Blood Institute Working Group on Hypertension: Barriers to Translation. Hypertension. 2020 04; 75(4):902-917. Sigmund CD, Carey RM, Appel LJ, Arnett DK, Bosworth HB, Cushman WC, Galis ZS, Green Parker M, Hall JE, Harrison DG, McDonough AA, Nicastro HL, Oparil S, Osborn JW, Raizada MK, Wright JD, Oh YS. PMID: 32063061; PMCID: PMC7067675.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimals
    23. Electrolyte and transporter responses to angiotensin II induced hypertension in female and male rats and mice. Acta Physiol (Oxf). 2020 05; 229(1):e13448. Veiras LC, McFarlin BE, Ralph DL, Buncha V, Prescott J, Shirvani BS, McDonough JC, Ha D, Giani J, Gurley SB, Mamenko M, McDonough AA. PMID: 31994810; PMCID: PMC7156336.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    24. Moving the Needle on Hypertension: What Knowledge Is Needed? Nutr Today. 2019 Nov-Dec; 54(6):248-256. Frame AA, Farquhar WB, Latulippe ME, McDonough AA, Wainford RD, Wynne BM. PMID: 34092814; PMCID: PMC8174552.
      View in: PubMed   Mentions: 2  
    25. Impact of angiotensin II-mediated stimulation of sodium transporters in the nephron assessed by computational modeling. Am J Physiol Renal Physiol. 2019 12 01; 317(6):F1656-F1668. Edwards A, McDonough AA. PMID: 31657247; PMCID: PMC6962509.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    26. Functional implications of the sex differences in transporter abundance along the rat nephron: modeling and analysis. Am J Physiol Renal Physiol. 2019 12 01; 317(6):F1462-F1474. Hu R, McDonough AA, Layton AT. PMID: 31566436; PMCID: PMC7132321.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    27. The Absence of the ACE N-Domain Decreases Renal Inflammation and Facilitates Sodium Excretion during Diabetic Kidney Disease. J Am Soc Nephrol. 2018 10; 29(10):2546-2561. Eriguchi M, Bernstein EA, Veiras LC, Khan Z, Cao DY, Fuchs S, McDonough AA, Toblli JE, Gonzalez-Villalobos RA, Bernstein KE, Giani JF. PMID: 30185469; PMCID: PMC6171283.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    28. Functional implications of sexual dimorphism of transporter patterns along the rat proximal tubule: modeling and analysis. Am J Physiol Renal Physiol. 2018 09 01; 315(3):F692-F700. Li Q, McDonough AA, Layton HE, Layton AT. PMID: 29846110; PMCID: PMC6172582.
      View in: PubMed   Mentions: 35     Fields:    Translation:Animals
    29. Downregulation of the Cl-/HCO3-Exchanger Pendrin in Kidneys of Mice with Cystic Fibrosis: Role in the Pathogenesis of Metabolic Alkalosis. Cell Physiol Biochem. 2018; 45(4):1551-1565. Varasteh Kia M, Barone S, McDonough AA, Zahedi K, Xu J, Soleimani M. PMID: 29482189.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    30. Blood pressure regulation by the angiotensin type 1 receptor in the proximal tubule. Curr Opin Nephrol Hypertens. 2018 01; 27(1):1-7. van Haaster MC, McDonough AA, Gurley SB. PMID: 29045337; PMCID: PMC5818672.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    31. Collecting Duct Nitric Oxide Synthase 1ß Activation Maintains Sodium Homeostasis During High Sodium Intake Through Suppression of Aldosterone and Renal Angiotensin II Pathways. J Am Heart Assoc. 2017 Oct 24; 6(10). Hyndman KA, Mironova EV, Giani JF, Dugas C, Collins J, McDonough AA, Stockand JD, Pollock JS. PMID: 29066445; PMCID: PMC5721879.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    32. Collecting duct prorenin receptor knockout reduces renal function, increases sodium excretion, and mitigates renal responses in ANG II-induced hypertensive mice. Am J Physiol Renal Physiol. 2017 Dec 01; 313(6):F1243-F1253. Prieto MC, Reverte V, Mamenko M, Kuczeriszka M, Veiras LC, Rosales CB, McLellan M, Gentile O, Jensen VB, Ichihara A, McDonough AA, Pochynyuk OM, Gonzalez AA. PMID: 28814438; PMCID: PMC5814641.
      View in: PubMed   Mentions: 38     Fields:    Translation:Animals
    33. Sexual Dimorphic Pattern of Renal Transporters and Electrolyte Homeostasis. J Am Soc Nephrol. 2017 Dec; 28(12):3504-3517. Veiras LC, Girardi ACC, Curry J, Pei L, Ralph DL, Tran A, Castelo-Branco RC, Pastor-Soler N, Arranz CT, Yu ASL, McDonough AA. PMID: 28774999; PMCID: PMC5698077.
      View in: PubMed   Mentions: 131     Fields:    Translation:AnimalsCells
    34. Potassium Homeostasis: The Knowns, the Unknowns, and the Health Benefits. Physiology (Bethesda). 2017 03; 32(2):100-111. McDonough AA, Youn JH. PMID: 28202621; PMCID: PMC5337831.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimals
    35. Cardiovascular benefits associated with higher dietary K+ vs. lower dietary Na+: evidence from population and mechanistic studies. Am J Physiol Endocrinol Metab. 2017 04 01; 312(4):E348-E356. McDonough AA, Veiras LC, Guevara CA, Ralph DL. PMID: 28174181; PMCID: PMC5406991.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimals
    36. Renal Collectrin Protects against Salt-Sensitive Hypertension and Is Downregulated by Angiotensin II. J Am Soc Nephrol. 2017 Jun; 28(6):1826-1837. Chu PL, Gigliotti JC, Cechova S, Bodonyi-Kovacs G, Chan F, Ralph DL, Howell N, Kalantari K, Klibanov AL, Carey RM, McDonough AA, Le TH. PMID: 28062568; PMCID: PMC5461790.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    37. Renal tubular angiotensin converting enzyme is responsible for nitro-L-arginine methyl ester (L-NAME)-induced salt sensitivity. Kidney Int. 2017 04; 91(4):856-867. Giani JF, Eriguchi M, Bernstein EA, Katsumata M, Shen XZ, Li L, McDonough AA, Fuchs S, Bernstein KE, Gonzalez-Villalobos RA. PMID: 27988209; PMCID: PMC5657384.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    38. Potassium Supplementation Prevents Sodium Chloride Cotransporter Stimulation During Angiotensin II Hypertension. Hypertension. 2016 10; 68(4):904-12. Veiras LC, Han J, Ralph DL, McDonough AA. PMID: 27600183; PMCID: PMC5016236.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    39. ISN Forefronts Symposium 2015: Maintaining Balance Under Pressure-Hypertension and the Proximal Tubule. Kidney Int Rep. 2016 Sep; 1(3):166-176. McDonough AA. PMID: 27840855; PMCID: PMC5102061.
      View in: PubMed   Mentions: 5  
    40. Paracellular epithelial sodium transport maximizes energy efficiency in the kidney. J Clin Invest. 2016 07 01; 126(7):2509-18. Pei L, Solis G, Nguyen MT, Kamat N, Magenheimer L, Zhuo M, Li J, Curry J, McDonough AA, Fields TA, Welch WJ, Yu AS. PMID: 27214555; PMCID: PMC4922683.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    41. Interleukin-17A Regulates Renal Sodium Transporters and Renal Injury in Angiotensin II-Induced Hypertension. Hypertension. 2016 07; 68(1):167-74. Norlander AE, Saleh MA, Kamat NV, Ko B, Gnecco J, Zhu L, Dale BL, Iwakura Y, Hoover RS, McDonough AA, Madhur MS. PMID: 27141060; PMCID: PMC4900947.
      View in: PubMed   Mentions: 105     Fields:    Translation:AnimalsCells
    42. Interleukin-1 Receptor Activation Potentiates Salt Reabsorption in Angiotensin II-Induced Hypertension via the NKCC2 Co-transporter in the Nephron. Cell Metab. 2016 Feb 09; 23(2):360-8. Zhang J, Rudemiller NP, Patel MB, Karlovich NS, Wu M, McDonough AA, Griffiths R, Sparks MA, Jeffs AD, Crowley SD. PMID: 26712462; PMCID: PMC4749461.
      View in: PubMed   Mentions: 77     Fields:    Translation:AnimalsCells
    43. The physiological role of glucagon-like peptide-1 in the regulation of renal function. Am J Physiol Renal Physiol. 2016 Jan 15; 310(2):F123-7. Farah LX, Valentini V, Pessoa TD, Malnic G, McDonough AA, Girardi AC. PMID: 26447224; PMCID: PMC5504384.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    44. Short-term nonpressor angiotensin II infusion stimulates sodium transporters in proximal tubule and distal nephron. Physiol Rep. 2015 Sep; 3(9). Nguyen MT, Han J, Ralph DL, Veiras LC, McDonough AA. PMID: 26347505; PMCID: PMC4600373.
      View in: PubMed   Mentions: 30     Fields:    
    45. Proximal tubule NHE3 activity is inhibited by beta-arrestin-biased angiotensin II type 1 receptor signaling. Am J Physiol Cell Physiol. 2015 Oct 15; 309(8):C541-50. Carneiro de Morais CP, Polidoro JZ, Ralph DL, Pessoa TD, Oliveira-Souza M, Barauna VG, Rebouças NA, Malnic G, McDonough AA, Girardi AC. PMID: 26246427; PMCID: PMC9560057.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    46. Salt Sensitivity in Response to Renal Injury Requires Renal Angiotensin-Converting Enzyme. Hypertension. 2015 Sep; 66(3):534-42. Giani JF, Bernstein KE, Janjulia T, Han J, Toblli JE, Shen XZ, Rodriguez-Iturbe B, McDonough AA, Gonzalez-Villalobos RA. PMID: 26150439; PMCID: PMC4825680.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    47. Maintaining Balance Under Pressure: Integrated Regulation of Renal Transporters During Hypertension. Hypertension. 2015 Sep; 66(3):450-5. McDonough AA, Nguyen MT. PMID: 26101347; PMCID: PMC4943879.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimals
    48. Renal NCC is unchanged in the midpregnant rat and decreased in the late pregnant rat despite avid renal Na+ retention. Am J Physiol Renal Physiol. 2015 Jul 01; 309(1):F63-70. West CA, McDonough AA, Masilamani SM, Verlander JW, Baylis C. PMID: 25925254; PMCID: PMC4490381.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    49. The intrarenal generation of angiotensin II is required for experimental hypertension. Curr Opin Pharmacol. 2015 Apr; 21:73-81. Giani JF, Shah KH, Khan Z, Bernstein EA, Shen XZ, McDonough AA, Gonzalez-Villalobos RA, Bernstein KE. PMID: 25616034; PMCID: PMC4380835.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    50. Renal transporter activation during angiotensin-II hypertension is blunted in interferon-γ-/- and interleukin-17A-/- mice. Hypertension. 2015 Mar; 65(3):569-76. Kamat NV, Thabet SR, Xiao L, Saleh MA, Kirabo A, Madhur MS, Delpire E, Harrison DG, McDonough AA. PMID: 25601932; PMCID: PMC4326622.
      View in: PubMed   Mentions: 119     Fields:    Translation:Animals
    51. Considerations when quantitating protein abundance by immunoblot. Am J Physiol Cell Physiol. 2015 Mar 15; 308(6):C426-33. McDonough AA, Veiras LC, Minas JN, Ralph DL. PMID: 25540176; PMCID: PMC4360027.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimals
    52. Paradoxical activation of the sodium chloride cotransporter (NCC) without hypertension in kidney deficient in a regulatory subunit of Na,K-ATPase, FXYD2. Physiol Rep. 2014 Dec 01; 2(12). Arystarkhova E, Ralph DL, Liu YB, Bouley R, McDonough AA, Sweadner KJ. PMID: 25472608; PMCID: PMC4332208.
      View in: PubMed   Mentions: 6     Fields:    
    53. Local pH domains regulate NHE3-mediated Na⁺ reabsorption in the renal proximal tubule. Am J Physiol Renal Physiol. 2014 Dec 01; 307(11):F1249-62. Brasen JC, Burford JL, McDonough AA, Holstein-Rathlou NH, Peti-Peterdi J. PMID: 25298526; PMCID: PMC4254968.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    54. Renal generation of angiotensin II and the pathogenesis of hypertension. Curr Hypertens Rep. 2014 Sep; 16(9):477. Giani JF, Janjulia T, Taylor B, Bernstein EA, Shah K, Shen XZ, McDonough AA, Bernstein KE, Gonzalez-Villalobos RA. PMID: 25097114; PMCID: PMC4277187.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    55. Of mice and men: modeling cardiovascular complexity in diabetes. Focus on "Mitochondrial inefficiencies and anoxic ATP hydrolysis capacities in diabetic rat heart". Am J Physiol Cell Physiol. 2014 Sep 15; 307(6):C497-8. Patel HH, McDonough AA. PMID: 25031018; PMCID: PMC4166741.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    56. Renal angiotensin-converting enzyme is essential for the hypertension induced by nitric oxide synthesis inhibition. J Am Soc Nephrol. 2014 Dec; 25(12):2752-63. Giani JF, Janjulia T, Kamat N, Seth DM, Blackwell WL, Shah KH, Shen XZ, Fuchs S, Delpire E, Toblli JE, Bernstein KE, McDonough AA, Gonzalez-Villalobos RA. PMID: 25012170; PMCID: PMC4243348.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    57. Increasing plasma [K+] by intravenous potassium infusion reduces NCC phosphorylation and drives kaliuresis and natriuresis. Am J Physiol Renal Physiol. 2014 May 01; 306(9):F1059-68. Rengarajan S, Lee DH, Oh YT, Delpire E, Youn JH, McDonough AA. PMID: 24598799; PMCID: PMC4010681.
      View in: PubMed   Mentions: 82     Fields:    Translation:AnimalsCells
    58. Compression injury in the mouse spinal cord elicits a specific proliferative response and distinct cell fate acquisition along rostro-caudal and dorso-ventral axes. Neuroscience. 2013 Dec 19; 254:1-17. McDonough A, Hoang AN, Monterrubio AM, Greenhalgh S, Martínez-Cerdeño V. PMID: 24042034.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    59. Differential regulation of Na+ transporters along nephron during ANG II-dependent hypertension: distal stimulation counteracted by proximal inhibition. Am J Physiol Renal Physiol. 2013 Aug 15; 305(4):F510-9. Nguyen MT, Lee DH, Delpire E, McDonough AA. PMID: 23720346; PMCID: PMC3891260.
      View in: PubMed   Mentions: 75     Fields:    Translation:Animals
    60. Need to quickly excrete K(+)? Turn off NCC. Kidney Int. 2013 May; 83(5):779-82. McDonough AA, Youn JH. PMID: 23633048; PMCID: PMC3644996.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    61. The absence of intrarenal ACE protects against hypertension. J Clin Invest. 2013 May; 123(5):2011-23. Gonzalez-Villalobos RA, Janjoulia T, Fletcher NK, Giani JF, Nguyen MT, Riquier-Brison AD, Seth DM, Fuchs S, Eladari D, Picard N, Bachmann S, Delpire E, Peti-Peterdi J, Navar LG, Bernstein KE, McDonough AA. PMID: 23619363; PMCID: PMC3638907.
      View in: PubMed   Mentions: 115     Fields:    Translation:Animals
    62. Proximal tubule specific knockout of the Na⁺/H⁺ exchanger NHE3: effects on bicarbonate absorption and ammonium excretion. J Mol Med (Berl). 2013 Aug; 91(8):951-63. Li HC, Du Z, Barone S, Rubera I, McDonough AA, Tauc M, Zahedi K, Wang T, Soleimani M. PMID: 23508938; PMCID: PMC3730089.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    63. Effects of ACE inhibition and ANG II stimulation on renal Na-Cl cotransporter distribution, phosphorylation, and membrane complex properties. Am J Physiol Cell Physiol. 2013 Jan 15; 304(2):C147-63. Lee DH, Maunsbach AB, Riquier-Brison AD, Nguyen MT, Fenton RA, Bachmann S, Yu AS, McDonough AA. PMID: 23114965; PMCID: PMC3587378.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    64. How does potassium supplementation lower blood pressure? Am J Physiol Renal Physiol. 2012 May 01; 302(9):F1224-5. McDonough AA, Nguyen MT. PMID: 22550158; PMCID: PMC3362178.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    65. Effects of K+-deficient diets with and without NaCl supplementation on Na+, K+, and H2O transporters' abundance along the nephron. Am J Physiol Renal Physiol. 2012 Jul 01; 303(1):F92-104. Nguyen MT, Yang LE, Fletcher NK, Lee DH, Kocinsky H, Bachmann S, Delpire E, McDonough AA. PMID: 22496411; PMCID: PMC3431149.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    66. Transport, cilia, and PKD: must we in (cyst) on interrelationships? Focus on "Increased Na+/H+ exchanger activity on the apical surface of a cilium-deficient cortical collecting duct principal cell model of polycystic kidney disease". Am J Physiol Cell Physiol. 2012 May 15; 302(10):C1434-5. Avner ED, McDonough AA, Sweeney WE. PMID: 22403786; PMCID: PMC3362002.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    67. AT1A angiotensin receptors in the renal proximal tubule regulate blood pressure. Cell Metab. 2011 Apr 06; 13(4):469-475. Gurley SB, Riquier-Brison ADM, Schnermann J, Sparks MA, Allen AM, Haase VH, Snouwaert JN, Le TH, McDonough AA, Koller BH, Coffman TM. PMID: 21459331; PMCID: PMC3070917.
      View in: PubMed   Mentions: 141     Fields:    Translation:AnimalsCells
    68. Mechanisms of proximal tubule sodium transport regulation that link extracellular fluid volume and blood pressure. Am J Physiol Regul Integr Comp Physiol. 2010 Apr; 298(4):R851-61. McDonough AA. PMID: 20106993; PMCID: PMC2853398.
      View in: PubMed   Mentions: 95     Fields:    Translation:HumansCells
    69. Angiotensin II stimulates trafficking of NHE3, NaPi2, and associated proteins into the proximal tubule microvilli. Am J Physiol Renal Physiol. 2010 Jan; 298(1):F177-86. Riquier-Brison AD, Leong PK, Pihakaski-Maunsbach K, McDonough AA. PMID: 19864301; PMCID: PMC2806122.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    70. Motoring down the microvilli. Focus on "PTH-induced internalization of apical membrane NaPi2a: role of actin and myosin VI". Am J Physiol Cell Physiol. 2009 Dec; 297(6):C1331-2. McDonough AA. PMID: 19776391; PMCID: PMC2793055.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    71. Isoform specificity of cardiac glycosides binding to human Na+,K+-ATPase alpha1beta1, alpha2beta1 and alpha3beta1. Eur J Pharmacol. 2009 Nov 10; 622(1-3):7-14. Hauck C, Potter T, Bartz M, Wittwer T, Wahlers T, Mehlhorn U, Scheiner-Bobis G, McDonough AA, Bloch W, Schwinger RH, Müller-Ehmsen J. PMID: 19751721; PMCID: PMC4948948.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    72. Narrative review: evolving concepts in potassium homeostasis and hypokalemia. Ann Intern Med. 2009 May 05; 150(9):619-25. Greenlee M, Wingo CS, McDonough AA, Youn JH, Kone BC. PMID: 19414841; PMCID: PMC4944758.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimals
    73. Renal NHE3 and NaPi2 partition into distinct membrane domains. Am J Physiol Cell Physiol. 2009 Apr; 296(4):C900-10. Riquier AD, Lee DH, McDonough AA. PMID: 19158399; PMCID: PMC2670655.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    74. Acute hypertension provokes acute trafficking of distal tubule Na-Cl cotransporter (NCC) to subapical cytoplasmic vesicles. Am J Physiol Renal Physiol. 2009 Apr; 296(4):F810-8. Lee DH, Riquier AD, Yang LE, Leong PK, Maunsbach AB, McDonough AA. PMID: 19144688; PMCID: PMC2670641.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    75. Recent advances in understanding integrative control of potassium homeostasis. Annu Rev Physiol. 2009; 71:381-401. Youn JH, McDonough AA. PMID: 18759636; PMCID: PMC4946439.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimals
    76. Rationale and design of CAPITA: a RCT of 13-valent conjugated pneumococcal vaccine efficacy among older adults. Neth J Med. 2008 Oct; 66(9):378-83. Hak E, Grobbee DE, Sanders EA, Verheij TJ, Bolkenbaas M, Huijts SM, Gruber WC, Tansey S, McDonough A, Thoma B, Patterson S, van Alphen AJ, Bonten MJ. PMID: 18990781.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    77. Effects of dietary salt on renal Na+ transporter subcellular distribution, abundance, and phosphorylation status. Am J Physiol Renal Physiol. 2008 Oct; 295(4):F1003-16. Yang LE, Sandberg MB, Can AD, Pihakaski-Maunsbach K, McDonough AA. PMID: 18653479; PMCID: PMC2576159.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    78. Connexin 30.3 is expressed in the kidney but not regulated by dietary salt or high blood pressure. Cell Commun Adhes. 2008 May; 15(1):219-30. Hanner F, Schnichels M, Zheng-Fischhöfer Q, Yang LE, Toma I, Willecke K, McDonough AA, Peti-Peterdi J. PMID: 18649192.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    79. Slc26a6 (PAT1) deletion downregulates the apical Na+/H+ exchanger in the straight segment of the proximal tubule. Am J Nephrol. 2008; 28(2):330-8. Petrovic S, Barone S, Wang Z, McDonough AA, Amlal H, Soleimani M. PMID: 18046080; PMCID: PMC2785905.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    80. AMPK activation with AICAR provokes an acute fall in plasma [K+]. Am J Physiol Cell Physiol. 2008 Jan; 294(1):C126-35. Zheng D, Perianayagam A, Lee DH, Brannan MD, Yang LE, Tellalian D, Chen P, Lemieux K, Marette A, Youn JH, McDonough AA. PMID: 18003746.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    81. Reducing blood pressure in SHR with enalapril provokes redistribution of NHE3, NaPi2, and NCC and decreases NaPi2 and ACE abundance. Am J Physiol Renal Physiol. 2007 Oct; 293(4):F1197-208. Yang LE, Leong PK, McDonough AA. PMID: 17652375.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    82. Evidence for gut factor in K+ homeostasis. Am J Physiol Renal Physiol. 2007 Aug; 293(2):F541-7. Lee FN, Oh G, McDonough AA, Youn JH. PMID: 17522262.
      View in: PubMed   Mentions: 34     Fields:    Translation:Animals
    83. ANG II provokes acute trafficking of distal tubule Na+-Cl(-) cotransporter to apical membrane. Am J Physiol Renal Physiol. 2007 Sep; 293(3):F662-9. Sandberg MB, Riquier AD, Pihakaski-Maunsbach K, McDonough AA, Maunsbach AB. PMID: 17507603.
      View in: PubMed   Mentions: 87     Fields:    Translation:Animals
    84. The proximal convoluted tubule is a target for the uroguanylin-regulated natriuretic response. J Pediatr Gastroenterol Nutr. 2006 Jul; 43 Suppl 1:S74-81. Elitsur N, Lorenz JN, Hawkins JA, Rudolph JA, Witte D, Yang LE, McDonough AA, Cohen MB. PMID: 16819406.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    85. Redistribution of distal tubule Na+-Cl- cotransporter (NCC) in response to a high-salt diet. Am J Physiol Renal Physiol. 2006 Aug; 291(2):F503-8. Sandberg MB, Maunsbach AB, McDonough AA. PMID: 16554416.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    86. Phenol injury-induced hypertension stimulates proximal tubule Na+/H+ exchanger activity. Am J Physiol Renal Physiol. 2006 Jun; 290(6):F1543-50. Leong PK, Yang LE, Landon CS, McDonough AA, Yip KP. PMID: 16390865.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    87. Modest dietary K+ restriction provokes insulin resistance of cellular K+ uptake and phosphorylation of renal outer medulla K+ channel without fall in plasma K+ concentration. Am J Physiol Cell Physiol. 2006 May; 290(5):C1355-63. Chen P, Guzman JP, Leong PK, Yang LE, Perianayagam A, Babilonia E, Ho JS, Youn JH, Wang WH, McDonough AA. PMID: 16354756.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    88. Effects of ACE inhibition on proximal tubule sodium transport. Am J Physiol Renal Physiol. 2006 Apr; 290(4):F854-63. Leong PK, Devillez A, Sandberg MB, Yang LE, Yip DK, Klein JB, McDonough AA. PMID: 16263808.
      View in: PubMed   Mentions: 31     Fields:    Translation:Animals
    89. Role of muscle in regulating extracellular [K+]. Semin Nephrol. 2005 Sep; 25(5):335-42. McDonough AA, Youn JH. PMID: 16139689.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    90. Redistribution of myosin VI from top to base of proximal tubule microvilli during acute hypertension. J Am Soc Nephrol. 2005 Oct; 16(10):2890-6. Yang LE, Maunsbach AB, Leong PK, McDonough AA. PMID: 16107581.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    91. Differential traffic of proximal tubule Na+ transporters during hypertension or PTH: NHE3 to base of microvilli vs. NaPi2 to endosomes. Am J Physiol Renal Physiol. 2004 Nov; 287(5):F896-906. Yang LE, Maunsbach AB, Leong PK, McDonough AA. PMID: 15265767.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    92. Dexamethasone treatment causes resistance to insulin-stimulated cellular potassium uptake in the rat. Am J Physiol Cell Physiol. 2004 Nov; 287(5):C1229-37. Rhee MS, Perianayagam A, Chen P, Youn JH, McDonough AA. PMID: 15213056.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    93. Acute hypotension induced by aortic clamp vs. PTH provokes distinct proximal tubule Na+ transporter redistribution patterns. Am J Physiol Regul Integr Comp Physiol. 2004 Oct; 287(4):R878-85. Leong PK, Yang LE, Lin HW, Holstein-Rathlou NH, McDonough AA. PMID: 15205183.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    94. Does membrane trafficking play a role in regulating the sodium/hydrogen exchanger isoform 3 in the proximal tubule? Curr Opin Nephrol Hypertens. 2003 Sep; 12(5):533-41. McDonough AA, Biemesderfer D. PMID: 12920402.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    95. Modest K+ restriction provokes insulin resistance of cellular K+ uptake without decrease in plasma K. Ann N Y Acad Sci. 2003 Apr; 986:625-7. Yang LE, Leong PK, Guzman JP, Rhee MS, McDonough AA. PMID: 12763903.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    96. Mechanisms of pressure natriuresis: how blood pressure regulates renal sodium transport. Ann N Y Acad Sci. 2003 Apr; 986:669-77. McDonough AA, Leong PK, Yang LE. PMID: 12763917.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    97. Chronic renal injury-induced hypertension alters renal NHE3 distribution and abundance. Am J Physiol Renal Physiol. 2003 May; 284(5):F1056-65. Yang LE, Zhong H, Leong PK, Perianayagam A, Campese VM, McDonough AA. PMID: 12554635.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    98. Angiotensin II clamp prevents the second step in renal apical NHE3 internalization during acute hypertension. Am J Physiol Renal Physiol. 2002 Nov; 283(5):F1142-50. Leong PK, Yang LE, Holstein-Rathlou NH, McDonough AA. PMID: 12372791.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    99. Diuretic response to acute hypertension is blunted during angiotensin II clamp. Am J Physiol Regul Integr Comp Physiol. 2002 Oct; 283(4):R837-42. Leong PK, Zhang Y, Yang LE, Holstein-Rathlou NH, McDonough AA. PMID: 12228052.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    100. Responses of proximal tubule sodium transporters to acute injury-induced hypertension. Am J Physiol Renal Physiol. 2003 Feb; 284(2):F313-22. Yang LE, Leong PK, Ye S, Campese VM, McDonough AA. PMID: 12388425.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    101. Skeletal muscle regulates extracellular potassium. Am J Physiol Renal Physiol. 2002 Jun; 282(6):F967-74. McDonough AA, Thompson CB, Youn JH. PMID: 11997312.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    102. Independent regulation of in vivo insulin action on glucose versus K(+) uptake by dietary fat and K(+) content. Diabetes. 2002 Apr; 51(4):915-20. Choi CS, Lee FN, McDonough AA, Youn JH. PMID: 11916907.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    103. Acute hypertension provokes internalization of proximal tubule NHE3 without inhibition of transport activity. Am J Physiol Renal Physiol. 2002 Apr; 282(4):F730-40. Yang L, Leong PK, Chen JO, Patel N, Hamm-Alvarez SF, McDonough AA. PMID: 11880335.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    104. The cardiac sodium pump: structure and function. Basic Res Cardiol. 2002; 97 Suppl 1:I19-24. McDonough AA, Velotta JB, Schwinger RH, Philipson KD, Farley RA. PMID: 12479229.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    105. Sodium pump isoform expression in heart failure: implication for treatment. Basic Res Cardiol. 2002; 97 Suppl 1:I25-30. Müller-Ehmsen J, McDonough AA, Farley RA, Schwinger RH. PMID: 12479230.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    106. Downstream shift in sodium pump activity along the nephron during acute hypertension. J Am Soc Nephrol. 2001 Nov; 12(11):2231-2240. Magyar CE, Zhang Y, Holstein-Rathlou NH, McDonough AA. PMID: 11675399.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    107. Ouabain and substrate affinities of human Na(+)-K(+)-ATPase alpha(1)beta(1), alpha(2)beta(1), and alpha(3)beta(1) when expressed separately in yeast cells. Am J Physiol Cell Physiol. 2001 Oct; 281(4):C1355-64. Müller-Ehmsen J, Juvvadi P, Thompson CB, Tumyan L, Croyle M, Lingrel JB, Schwinger RH, McDonough AA, Farley RA. PMID: 11546674.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    108. All human Na(+)-K(+)-ATPase alpha-subunit isoforms have a similar affinity for cardiac glycosides. Am J Physiol Cell Physiol. 2001 Oct; 281(4):C1336-43. Wang J, Velotta JB, McDonough AA, Farley RA. PMID: 11546672.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    109. UT-A urea transporter protein in heart: increased abundance during uremia, hypertension, and heart failure. Circ Res. 2001 Jul 20; 89(2):139-45. Duchesne R, Klein JD, Velotta JB, Doran JJ, Rouillard P, Roberts BR, McDonough AA, Sands JM. PMID: 11463720.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    110. Region specific regulation of sodium pump isoform and Na,Ca-exchanger expression in the failing human heart--right atrium vs left ventricle. Cell Mol Biol (Noisy-le-grand). 2001 Mar; 47(2):373-81. Müller-Ehmsen J, Wang J, Schwinger RH, McDonough AA. PMID: 11357898.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    111. Glucocorticoids increase sodium pump alpha(2)- and beta(1)-subunit abundance and mRNA in rat skeletal muscle. Am J Physiol Cell Physiol. 2001 Mar; 280(3):C509-16. Thompson CB, Dorup I, Ahn J, Leong PK, McDonough AA. PMID: 11171570.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    112. Short-term K(+) deprivation provokes insulin resistance of cellular K(+) uptake revealed with the K(+) clamp. Am J Physiol Renal Physiol. 2001 Jan; 280(1):F95-F102. Choi CS, Thompson CB, Leong PK, McDonough AA, Youn JH. PMID: 11133519.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    113. Proximal tubule Na transporter responses are the same during acute and chronic hypertension. Am J Physiol Renal Physiol. 2000 Aug; 279(2):F358-69. Magyar CE, Zhang Y, Holstein-Rathlou NH, McDonough AA. PMID: 10919857.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    114. Developmental change in Na,K-ATPase alpha1 and beta1 expression in normal and hypothyroid rat renal cortex. Am J Nephrol. 2000 May-Jun; 20(3):225-31. Nakhoul F, Thompson CB, McDonough AA. PMID: 10878407.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    115. Molecular mechanisms of sodium transport inhibition in proximal tubule during acute hypertension. Curr Opin Nephrol Hypertens. 2000 Mar; 9(2):149-56. Magyar CE, McDonough AA. PMID: 10757220.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    116. Temporal responses of oxidative vs. glycolytic skeletal muscles to K+ deprivation: Na+ pumps and cell cations. Am J Physiol. 1999 06; 276(6):C1411-9. Thompson CB, Choi C, Youn JH, McDonough AA. PMID: 10362605.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    117. In vivo PTH provokes apical NHE3 and NaPi2 redistribution and Na-K-ATPase inhibition. Am J Physiol. 1999 05; 276(5):F711-9. Zhang Y, Norian JM, Magyar CE, Holstein-Rathlou NH, Mircheff AK, McDonough AA. PMID: 10330053.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    118. Reduced sodium pump alpha1, alpha3, and beta1-isoform protein levels and Na+,K+-ATPase activity but unchanged Na+-Ca2+ exchanger protein levels in human heart failure. Circulation. 1999 Apr 27; 99(16):2105-12. Schwinger RH, Wang J, Frank K, Müller-Ehmsen J, Brixius K, McDonough AA, Erdmann E. PMID: 10217649.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    119. Can ENaC regulate ICF as well as ECF volume? Focus on "osmotic pressure regulates alpha beta gamma-rENaC expressed in Xenopus oocytes". Am J Physiol. 1998 11; 275(5):C1179-81. McDonough AA. PMID: 9814963.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    120. Redistribution of Na+/H+ exchanger isoform NHE3 in proximal tubules induced by acute and chronic hypertension. Am J Physiol. 1998 10; 275(4):F565-75. Yip KP, Tse CM, McDonough AA, Marsh DJ. PMID: 9755128.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    121. Reversible effects of acute hypertension on proximal tubule sodium transporters. Am J Physiol. 1998 04; 274(4):C1090-100. Zhang Y, Magyar CE, Norian JM, Holstein-Rathlou NH, Mircheff AK, McDonough AA. PMID: 9575807.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    122. The cytochrome P-450 inhibitor cobalt chloride prevents inhibition of renal Na,K-ATPase and redistribution of apical NHE-3 during acute hypertension. J Am Soc Nephrol. 1998 Apr; 9(4):531-7. Zhang YB, Magyar CE, Holstein-Rathlou NH, McDonough AA. PMID: 9555654.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    123. Posttranscriptional upregulation of Na(+)-K(+)-ATPase activity in newborn guinea pig renal cortex. Am J Physiol. 1997 Aug; 273(2 Pt 2):F254-63. Guillery EN, Huss DJ, McDonough AA, Klein LC. PMID: 9277586.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    124. Skeletal muscle Na,K-ATPase alpha and beta subunit protein levels respond to hypokalemic challenge with isoform and muscle type specificity. J Biol Chem. 1996 Dec 20; 271(51):32653-8. Thompson CB, McDonough AA. PMID: 8955095.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    125. Regional expression of sodium pump subunits isoforms and Na+-Ca++ exchanger in the human heart. J Clin Invest. 1996 Oct 01; 98(7):1650-8. Wang J, Schwinger RH, Frank K, Müller-Ehmsen J, Martin-Vasallo P, Pressley TA, Xiang A, Erdmann E, McDonough AA. PMID: 8833915; PMCID: PMC507599.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    126. Rapid redistribution and inhibition of renal sodium transporters during acute pressure natriuresis. Am J Physiol. 1996 Jun; 270(6 Pt 2):F1004-14. Zhang Y, Mircheff AK, Hensley CB, Magyar CE, Warnock DG, Chambrey R, Yip KP, Marsh DJ, Holstein-Rathlou NH, McDonough AA. PMID: 8764320.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    127. Subcellular distribution of sodium pump isoform subunits in mammalian cardiac myocytes. Am J Physiol. 1996 Apr; 270(4 Pt 1):C1221-7. McDonough AA, Zhang Y, Shin V, Frank JS. PMID: 8928749.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    128. Role of skeletal muscle sodium pumps in the adaptation to potassium deprivation. Acta Physiol Scand. 1996 Mar; 156(3):295-304. McDonough AA, Thompson CB. PMID: 8729690.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    129. Renal Na+/H+ exchanger isoforms and their regulation by thyroid hormone. Am J Physiol. 1996 Feb; 270(2 Pt 1):C585-92. Azuma KK, Balkovetz DF, Magyar CE, Lescale-Matys L, Zhang Y, Chambrey R, Warnock DG, McDonough AA. PMID: 8779923.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    130. Reciprocal regulation of cardiac Na-K-ATPase and Na/Ca exchanger: hypertension, thyroid hormone, development. Am J Physiol. 1995 Sep; 269(3 Pt 1):C675-82. Magyar CE, Wang J, Azuma KK, McDonough AA. PMID: 7573397.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    131. Significance of sodium pump isoforms in digitalis therapy. J Mol Cell Cardiol. 1995 Apr; 27(4):1001-9. McDonough AA, Wang J, Farley RA. PMID: 7563097.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    132. Expression of Na(+)-K(+)-ATPase alpha- and beta-subunits along rat nephron: isoform specificity and response to hypokalemia. Am J Physiol. 1994 Oct; 267(4 Pt 1):C901-8. McDonough AA, Magyar CE, Komatsu Y. PMID: 7943283.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    133. Amiodarone decreases Na,K-ATPase alpha 2 and beta 2 expression specifically in cardiac ventricle. J Mol Cell Cardiol. 1994 Apr; 26(4):417-24. Hensley CB, Bersohn MM, Sarma JS, Singh BN, McDonough AA. PMID: 8071999.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    134. Nicotine downregulates alpha 2 isoform of Na,K-ATPase at the blood-brain barrier and brain in rats. Biochem Biophys Res Commun. 1994 Mar 30; 199(3):1422-7. Wang L, McComb JG, Weiss MH, McDonough AA, Zlokovic BV. PMID: 8147886.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    135. Surplus Na+ pumps: how low-K(+)-incubated LLC-PK1 cells respond to K+ restoration. Am J Physiol. 1993 Oct; 265(4 Pt 1):C887-92. Lescale-Matys L, Putnam DS, McDonough AA. PMID: 8238313.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    136. Surface and intracellular pools of Na,K-ATPase catalytic and immuno-activities in rat exorbital lacrimal gland. Exp Eye Res. 1993 Oct; 57(4):403-13. Bradley ME, Azuma KK, McDonough AA, Mircheff AK, Wood RL. PMID: 8282026.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    137. Thyroid hormone specifically regulates skeletal muscle Na(+)-K(+)-ATPase alpha 2- and beta 2-isoforms. Am J Physiol. 1993 Sep; 265(3 Pt 1):C680-7. Azuma KK, Hensley CB, Tang MJ, McDonough AA. PMID: 8214025.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    138. Regulation of Na,K-ATPase activity. Curr Opin Nephrol Hypertens. 1993 Sep; 2(5):725-34. McDonough AA, Farley RA. PMID: 7922215.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    139. Differential expression of Na,K-ATPase alpha and beta subunit isoforms at the blood-brain barrier and the choroid plexus. J Biol Chem. 1993 Apr 15; 268(11):8019-25. Zlokovic BV, Mackic JB, Wang L, McComb JG, McDonough A. PMID: 8385133.
      View in: PubMed   Mentions: 35     Fields:    Translation:Animals
    140. Na(+)-K(+)-ATPase alpha 1- and beta 1-subunit degradation: evidence for multiple subunit specific rates. Am J Physiol. 1993 Mar; 264(3 Pt 1):C583-90. Lescale-Matys L, Putnam DS, McDonough AA. PMID: 8384785.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    141. Expression of Na,K-ATPase at the blood-brain interface. Adv Exp Med Biol. 1993; 331:55-60. Zlokovic BV, Wang L, Mackic JB, Saraj AJ, McComb JG, McDonough A. PMID: 8392783.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    142. Physiologic rationale for multiple sodium pump isoforms. Differential regulation of alpha 1 vs alpha 2 by ionic stimuli. Ann N Y Acad Sci. 1992 Nov 30; 671:156-68; discussion 168-9. McDonough AA, Azuma KK, Lescale-Matys L, Tang MJ, Nakhoul F, Hensley CB, Komatsu Y. PMID: 1337670.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    143. Low K+ increases Na(+)-K(+)-ATPase alpha- and beta-subunit mRNA and protein abundance in cultured renal proximal tubule cells. Am J Physiol. 1992 Aug; 263(2 Pt 1):C436-42. Tang MJ, McDonough AA. PMID: 1381148.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    144. Synthesis and translocation of Na(+)-K(+)-ATPase alpha- and beta-subunits to plasma membrane in MDCK cells. Am J Physiol. 1992 Feb; 262(2 Pt 1):C470-83. Mircheff AK, Bowen JW, Yiu SC, McDonough AA. PMID: 1311503.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    145. Thyroid hormone induction of rat myocardial Na(+)-K(+)-ATPase: alpha 1-, alpha 2-, and beta 1-mRNA and -protein levels at steady state. Am J Physiol. 1992 Feb; 262(2 Pt 1):C484-92. Hensley CB, Azuma KK, Tang MJ, McDonough AA. PMID: 1311504.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    146. Differential regulation of sodium pump isoforms in heart. Semin Nephrol. 1992 Jan; 12(1):49-55. McDonough AA, Hensley CB, Azuma KK. PMID: 1312744.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    147. Rapid hypertensinogenic effect of lead: studies in the spontaneously hypertensive rat. Toxicol Ind Health. 1992 Jan-Apr; 8(1-2):89-102. Nakhoul F, Kayne LH, Brautbar N, Hu MS, McDonough A, Eggena P, Golub MS, Berger M, Chang CT, Jamgotchian N, et al. PMID: 1542888.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsPHPublic Health
    148. Hypokalemia decreases Na(+)-K(+)-ATPase alpha 2- but not alpha 1-isoform abundance in heart, muscle, and brain. Am J Physiol. 1991 May; 260(5 Pt 1):C958-64. Azuma KK, Hensley CB, Putnam DS, McDonough AA. PMID: 1852110.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    149. Regulation of testicular P-450 cholesterol side-chain cleavage and P-450 C17-20 lyase/C17 hydroxylase enzymes in the neonatal and adult rat. Acta Endocrinol (Copenh). 1991 Apr; 124(4):449-54. Lu Y, McDonough A, Farley RA, Warren DW. PMID: 2031442.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    150. Low K+ increases Na,K-ATPase abundance in LLC-PK1/Cl4 cells by differentially increasing beta, and not alpha, subunit mRNA. J Biol Chem. 1990 Oct 15; 265(29):17935-40. Lescale-Matys L, Hensley CB, Crnkovic-Markovic R, Putnam DS, McDonough AA. PMID: 2170401.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    151. Differential regulation of Na,K-ATPase alpha 1, alpha 2, and beta subunit mRNA and protein levels by thyroid hormone. J Biol Chem. 1990 Aug 25; 265(24):14308-14. Horowitz B, Hensley CB, Quintero M, Azuma KK, Putnam D, McDonough AA. PMID: 2167313.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    152. Ionic regulation of the biosynthesis of NaK-ATPase subunits. Semin Nephrol. 1990 Jul; 10(4):400-9. McDonough AA, Tang MJ, Lescale-Matys L. PMID: 2166328.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    153. The sodium pump needs its beta subunit. FASEB J. 1990 Apr 01; 4(6):1598-605. McDonough AA, Geering K, Farley RA. PMID: 2156741.
      View in: PubMed   Mentions: 74     Fields:    Translation:AnimalsCells
    154. alar4, a constitutive mutant of the A system for amino acid transport, has increased abundance of the Na+,K+-ATPase and mRNA for alpha 1 subunit of this enzyme. Proc Natl Acad Sci U S A. 1989 Oct; 86(20):7984-8. Qian NX, Jones M, McDonough A, Englesberg E. PMID: 2554299; PMCID: PMC298197.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    155. Thyroid hormone regulates alpha and alpha + isoforms of Na,K-ATPase during development in neonatal rat brain. J Biol Chem. 1988 Nov 25; 263(33):17643-9. Schmitt CA, McDonough AA. PMID: 2846574.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    156. Patterns of mRNA expression during early cell growth differ in kidney epithelial cells destined to undergo compensatory hypertrophy versus regenerative hyperplasia. Proc Natl Acad Sci U S A. 1988 Sep; 85(18):6768-72. Norman JT, Bohman RE, Fischmann G, Bowen JW, McDonough A, Slamon D, Fine LG. PMID: 3413124; PMCID: PMC282059.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    157. Thyroid hormone coordinately regulates Na+-K+-ATPase alpha- and beta-subunit mRNA levels in kidney. Am J Physiol. 1988 Feb; 254(2 Pt 1):C323-9. McDonough AA, Brown TA, Horowitz B, Chiu R, Schlotterbeck J, Bowen J, Schmitt CA. PMID: 2831727.
      View in: PubMed   Mentions: 24     Fields:    Translation:Animals
    158. Isozymes of dog heart Na+-K+-ATPase are immunologically similar to isozymes in brain. Am J Physiol. 1987 Dec; 253(6 Pt 1):C862-5. McDonough AA, Schmitt CA. PMID: 2827499.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    159. Enrichment of Na+-Ca2+ exchange in cardiac sarcolemmal vesicles by alkaline extraction. Biochim Biophys Acta. 1987 May 12; 899(1):59-66. Philipson KD, McDonough AA, Frank JS, Ward R. PMID: 3567192.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    160. Molecular cloning and sequence analysis of the (Na+ + K+)-ATPase beta subunit from dog kidney. Biochim Biophys Acta. 1987 Apr 08; 912(2):244-53. Brown TA, Horowitz B, Miller RP, McDonough AA, Farley RA. PMID: 3030434.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    161. Pretranslational regulation of Na-K-ATPase in cultured canine kidney cells by low K+. Am J Physiol. 1987 Feb; 252(2 Pt 1):C179-89. Bowen JW, McDonough A. PMID: 3030119.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    162. Developmental and thyroid hormone regulation of two molecular forms of Na+-K+-ATPase in brain. J Biol Chem. 1986 Aug 05; 261(22):10439-44. Schmitt CA, McDonough AA. PMID: 3015931.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    163. Isolation of partial cDNAs for rat liver and muscle glycogen phosphorylase isozymes. FEBS Lett. 1986 Jul 07; 202(2):282-8. Osawa S, Chiu RH, McDonough A, Miller TB, Johnson GL. PMID: 2424788.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    164. Mapping subcellular distribution of Na+-K+-ATPase in rat parotid gland. Am J Physiol. 1986 Mar; 250(3 Pt 1):C430-41. Conteas CN, McDonough AA, Kozlowski TR, Hensley CB, Wood RL, Mircheff AK. PMID: 3006505.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    165. Immunodetection of Na,K-ATPase in guinea-pig retinal layers, cornea and lens. Exp Eye Res. 1985 May; 40(5):667-74. McDonough A. PMID: 2988990.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    166. Comparison of subunits of cardiac, brain, and kidney Na+-K+-ATPase. Am J Physiol. 1985 Mar; 248(3 Pt 1):C247-51. McDonough A, Schmitt C. PMID: 2983564.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    167. Assembly of the (Na+ + K+)-adenosine triphosphatase. Post-translational membrane integration of the alpha subunit. J Biol Chem. 1984 Feb 25; 259(4):2629-35. Hiatt A, McDonough AA, Edelman IS. PMID: 6199349.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    168. Characteristics of antibodies to guinea pig (Na+ + K+)-adenosine triphosphatase and their use in cell-free synthesis studies. J Membr Biol. 1982; 69(1):13-22. McDonough AA, Hiatt A, Edelman IS. PMID: 6288956.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    169. Hana kai ii: a 17-day dry saturation dive at 18.6 ATA. III. Body fluid balance. Undersea Biomed Res. 1977 Sep; 4(3):247-65. Hong SK, Claybaugh JR, Frattali V, Johnson R, Kurata F, Matsuda M, McDonough AA, Paganelli CV, Smith RM, Webb P. PMID: 910316.
      View in: PubMed   Mentions: 3     Fields:    
    Alicia's Networks
    Concepts (524)
    Derived automatically from this person's publications.
    Explore
    _
    Co-Authors (11)
    People in Profiles who have published with this person.
    Explore
    _
    Similar People (60)
    People who share similar concepts with this person.
    Explore
    _
    Same Department
    Search Department
    _

    NIH Funding Acknowledgment: Important - All publications resulting from the utilization of SC CTSI resources are required to credit the SC CTSI grant by including the NIH funding acknowledgment and must comply with the NIH Public Access Policy.

    This site is running Profiles RNS version UCSF-v3.1.0-6-g69de2244 on PROFILES-PWEB03. We use cookies to operate our website. We also use cookies to analyze our site’s performance and improve your experience on our site. For more information about how we use cookies, please see our Website Terms of Use.