Ken Bernstein

Title(s)Adjunct Instructor
SchoolUSC Sol Price School of Public Policy
Address650 Childs Way
University Park Campus
Los Angeles CA 90089
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Stereotactic Radiosurgery Versus Observation in Small- and Medium-Sized Vestibular Schwannoma Patients With Normal Hearing: A Retrospective International Multicenter Study. Neurosurgery. 2025 Sep 16. Hajikarimloo B, Bin-Alamer O, Tos SM, Mantziaris G, Ishaque M, Abou-Al-Shaar H, Peker S, Samanci Y, Pelcher I, Begley S, Goenka A, Schulder M, Tourigny JN, Mathieu D, Hamel A, Briggs RG, Yu C, Zada G, Giannotta SL, Speckter H, Palque S, Tripathi M, Kumar S, Kaur R, Kumar N, Rogowski B, Shepard MJ, Johnson BA, Trifiletti DM, Warnick RE, Mashiach E, De Nigris Vasconcellos F, Bernstein K, Schnurman Z, Alzate J, Kondziolka D, Sheehan JP. PMID: 40956102.
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    2. Multicenter Retrospective Study of Stereotactic Radiosurgery for Gynecological Cancer Brain Metastases. Neurosurgery. 2025 Jul 07. Billau M, Hamel A, Tourigny JN, Iorio-Morin C, Liscak R, May J, Niranjan A, Wei Z, Lunsford LD, Luy DD, Jose S, Scanlon S, Silverman J, Mullen R, Bernstein K, Kondziolka D, Peker S, Samanci Y, Braunstein S, Phuong C, Sheehan J, Pikis S, Kosyakovsky J, Prasad RN, Palmer JD, Bailey D, Zacharia BE, Cifarelli CP, Icaza DA, Cifarelli DT, Wegner RE, Shepard MJ, Bowden GN, Wandrey N, Rusthoven CG, Hintz EB, Schulder M, Goenka A, Peterson JL, Mathieu D. PMID: 40622139.
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    3. Clinical outcomes following stereotactic radiosurgery for brain metastases from sarcoma primaries: An international multicenter analysis. Cancer. 2025 Jul 01; 131(13):e35931. Singh R, Roubil JG, Bowden G, Mathieu D, Carrier L, Shepard M, Kite T, Wegner RE, Picozzi P, Franzini A, Yang HC, Lee CC, Wei Z, Hoang A, Hess J, Fathima B, Chiang V, Peker S, Samanci Y, Liscak R, Simonova G, Paro M, Kamen S, McInerney J, Zacharia BE, Sumi T, Kano H, Bueno A, Dono A, Blanco AI, Esquenazi Y, Alzate JD, Briggs RG, Yu C, Zada G, Cifarelli CP, Cifarelli DT, Almeida T, Benjamin C, Costa R, Speckter H, Gonzalez I, Marinho Andrade de Moura AC, Kondziolka D, Bernstein K, Shaaban A, Lunsford LD, Niranjan A, Konieczkowski DJ, Palmer JD, Sheehan JP. PMID: 40543045.
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    4. Adverse functions of neutrophils are regulated by neutrophilic angiotensin-converting enzyme in immune complex-mediated crescentic glomerulonephritis. Am J Physiol Renal Physiol. 2025 Jul 01; 329(1):F190-F201. Saito S, Kumakura S, Khan Z, Bernstein EA, Karumanchi SA, Bernstein KE, Yamashita M. PMID: 40526025.
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    5. Boosting angiotensin-converting enzyme (ACE) in microglia protects against Alzheimer's disease in 5xFAD mice. Nat Aging. 2025 Jul; 5(7):1280-1294. Gomez AR, Byun HR, Wu S, Muhammad AKMG, Ikbariyeh J, Chen J, Muro A, Li L, Bernstein KE, Ainsworth R, Tourtellotte WG. PMID: 40490625.
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    6. Outcomes of stereotactic radiosurgery for pituitary metastases: an international multi-institutional study. Pituitary. 2025 May 29; 28(3):69. Abou-Al-Shaar H, Albalkhi I, Shariff RK, Mallela AN, Fazeli PK, Tos SM, Mantziaris G, Meng Y, Bernstein K, Kaisman-Elbaz T, Abofani H, Lin YY, Lee CC, Tripathi M, Upadhyay R, Palmer JD, Nabeel AM, Reda WA, Tawadros SR, Abdelkarim K, El-Shehaby AMN, Emad RM, Peker S, Samanci Y, Wegner RE, Shepard MJ, Liscak R, Simonova G, Almeida T, Benjamin C, Kondziolka D, Sheehan JP, Niranjan A, Hadjipanayis CG, Lunsford LD. PMID: 40442537.
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    7. Peroxisome proliferator-activated receptor alpha is an essential factor in enhanced macrophage immune function induced by angiotensin-converting enzyme. Cell Mol Immunol. 2025 Mar; 22(3):243-259. Saito S, Cao DY, Bernstein EA, Shibata T, Jones AE, Rios A, Hoshi AO, Stotland AB, Nishi EE, Van Eyk JE, Divakaruni A, Khan Z, Bernstein KE. PMID: 39910334; PMCID: PMC11868401.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    8. Inhibition of the angiotensin-converting enzyme N-terminal catalytic domain prevents endogenous opioid degradation in brain tissue. bioRxiv. 2025 Jan 21. Hanak F, Swanson JL, Felczak K, Bernstein KE, More SS, Rothwell PE. PMID: 39896517; PMCID: PMC11785082.
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    9. Risk of new tumor, carotid stenosis, and stroke after stereotactic radiosurgery for pituitary tumor: A multicenter study of 2254 patients with imaging follow-up. Neuro Oncol. 2024 Dec 05; 26(12):2328-2338. Dumot C, Mantziaris G, Dayawansa S, Brantley C, Lee CC, Yang HC, Peker S, Samanci Y, Mathieu D, Tourigny JN, Martinez Moreno N, Martinez Alvarez R, Chytka T, Liscak R, Speckter H, Lazo E, Brito A, Picozzi P, Franzini A, Alzate J, Mashiach E, Bernstein K, Kondziolka D, Tripathi M, Bowden GN, Warnick RE, Sheehan D, Sheehan K, Fuentes A, Jane JA, Vance ML, Sheehan JP. PMID: 39028740; PMCID: PMC11630564.
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    10. Outcomes Associated With Stereotactic Radiosurgery After Multiple Resections of Nonfunctioning Pituitary Macroadenomas: An International, Multicenter Case Series. Neurosurgery. 2024 Nov 07; 97(1):182-190. Grogan D, Dumot C, Mantziaris G, Tos SM, Tewari A, Dayawansa S, Sheehan K, Sheehan D, Peker S, Samanci Y, Nabeel AM, Reda WA, Tawadros SR, AbdelKarim K, El-Shehaby AMN, Emad RM, Abdelsalam AR, Liscak R, May J, Mashiach E, Vasconcellos FN, Bernstein K, Kondziolka D, Speckter H, Mota R, Brito A, Bindal SK, Niranjan A, Lunsford LD, Benjamin CG, Almeida TAL, Mathieu D, Tourigny JN, Tripathi M, Palmer JD, Mao J, Matsui J, Crooks J, Wegner RE, Shepard MJ, Sheehan J. PMID: 39508579.
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    11. Vestibular Schwannoma Koos Grade I International Study of Active Surveillance Versus Stereotactic Radiosurgery: The VISAS-K1 Study. Neurosurgery. 2025 Jan 01; 96(1):41-49. Bin-Alamer O, Abou-Al-Shaar H, Peker S, Samanci Y, Pelcher I, Begley S, Goenka A, Schulder M, Tourigny JN, Mathieu D, Hamel A, Briggs RG, Yu C, Zada G, Giannotta SL, Speckter H, Palque S, Tripathi M, Kumar S, Kaur R, Kumar N, Rogowski B, Shepard MJ, Johnson BA, Trifiletti DM, Warnick RE, Dayawansa S, Mashiach E, Vasconcellos FN, Bernstein K, Schnurman Z, Alzate J, Kondziolka D, Sheehan JP. PMID: 39503441.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Vestibular Schwannoma Koos Grade II International Study of Active Surveillance Versus Stereotactic Radiosurgery: The VISAS-K2 Study. Neurosurgery. 2025 Jan 01; 96(1):50-58. Bin-Alamer O, Abou-Al-Shaar H, Peker S, Samanci Y, Pelcher I, Begley S, Goenka A, Schulder M, Tourigny JN, Mathieu D, Hamel A, Briggs RG, Yu C, Zada G, Giannotta SL, Speckter H, Palque S, Tripathi M, Kumar S, Kaur R, Kumar N, Rogowski B, Shepard MJ, Johnson BA, Trifiletti DM, Warnick RE, Dayawansa S, Mashiach E, Vasconcellos FN, Bernstein K, Schnurman Z, Alzate J, Kondziolka D, Sheehan JP. PMID: 39503444.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Tumor derived cell-free nucleic acid upregulates programmed death-ligand 1 expression in neutrophil via intracellular Toll-like receptor signaling. Cancer Commun (Lond). 2025 Jan; 45(1):4-8. Saito S, Cao DY, Shibata T, Liu Y, Otagiri-Hoshi A, Cui X, Bernstein KE. PMID: 39474920; PMCID: PMC11758147.
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    14. Efficacy and safety of a third stereotactic radiosurgery for recurrent trigeminal neuralgia: an international, multicenter study. Acta Neurochir (Wien). 2024 10 23; 166(1):422. De Nigris Vasconcellos F, Alzate JD, Mashiach E, Meng Y, Santhumayor B, Bernstein K, Pichardo-Rojas P, Dono A, Damron EP, Blanco AI, Esquenazi Y, Urgosik D, May J, Lee CC, Yang HC, Kawalec P, Kaufmann AM, Mathieu D, Iorio-Morin C, Picozzi P, Franzini A, Tripathi M, Peker S, Samanci Y, Almeida T, Benjamin C, Kondziolka D, Sheehan J. PMID: 39441236.
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    15. Longitudinal deep neural networks for assessing metastatic brain cancer on a large open benchmark. Nat Commun. 2024 09 17; 15(1):8170. Link KE, Schnurman Z, Liu C, Kwon YJF, Jiang LY, Nasir-Moin M, Neifert S, Alzate JD, Bernstein K, Qu T, Chen V, Yang E, Golfinos JG, Orringer D, Kondziolka D, Oermann EK. PMID: 39289405; PMCID: PMC11408643.
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    16. Proteomic Analysis of Human Macrophages Overexpressing Angiotensin-Converting Enzyme. Int J Mol Sci. 2024 Jun 27; 25(13). Oosthuizen D, Ganief TA, Bernstein KE, Sturrock ED. PMID: 39000163; PMCID: PMC11240931.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    17. Angiotensin Converting Enzyme (ACE) expression in microglia reduces amyloid β deposition and neurodegeneration by increasing SYK signaling and endolysosomal trafficking. bioRxiv. 2024 May 21. Gomez AR, Byun HR, Wu S, Muhammad AG, Ikbariyeh J, Chen J, Muro A, Li L, Bernstein KE, Ainsworth R, Tourtellotte WG. PMID: 38712251; PMCID: PMC11071489.
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    18. Classical and nonclassical effects of angiotensin-converting enzyme: How increased ACE enhances myeloid immune function. J Biol Chem. 2024 06; 300(6):107388. Bernstein KE, Cao D, Shibata T, Saito S, Bernstein EA, Nishi E, Yamashita M, Tourtellotte WG, Zhao TV, Khan Z. PMID: 38763333; PMCID: PMC11208953.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    19. Peroxisome proliferator-activated receptor alpha is essential factor in enhanced macrophage immune function induced by angiotensin converting enzyme. Res Sq. 2024 Apr 22. Saito S, Cao D, Bernstein EA, Jones AE, Rios A, Hoshi AO, Stotland AB, Nishi EE, Shibata T, Ahmed F, Van Eyk JE, Divakaruni A, Khan Z, Bernstein KE. PMID: 38746124; PMCID: PMC11092867.
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    20. Vestibular Schwannoma International Study of Active Surveillance Versus Stereotactic Radiosurgery: The VISAS Study. Int J Radiat Oncol Biol Phys. 2024 Oct 01; 120(2):454-464. Bin-Alamer O, Abou-Al-Shaar H, Peker S, Samanci Y, Pelcher I, Begley S, Goenka A, Schulder M, Tourigny JN, Mathieu D, Hamel A, Briggs RG, Yu C, Zada G, Giannotta SL, Speckter H, Palque S, Tripathi M, Kumar S, Kaur R, Kumar N, Rogowski B, Shepard MJ, Johnson BA, Trifiletti DM, Warnick RE, Dayawansa S, Mashiach E, Vasconcellos FN, Bernstein K, Schnurman Z, Alzate J, Kondziolka D, Sheehan JP. PMID: 38588868.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    21. Stereotactic radiosurgery for nonfunctioning pituitary tumor: A multicenter study of new pituitary hormone deficiency. Neuro Oncol. 2024 04 05; 26(4):715-723. Dumot C, Mantziaris G, Dayawansa S, Peker S, Samanci Y, Nabeel AM, Reda WA, Tawadros SR, Abdelkarim K, El-Shehaby AMN, Emad RM, Abdelsalam AR, Liscak R, May J, Mashiach E, De Nigris Vasconcellos F, Bernstein K, Kondziolka D, Speckter H, Mota R, Brito A, Bindal SK, Niranjan A, Lunsford DL, Benjamin CG, Abrantes de Lacerda Almeida T, Mao J, Mathieu D, Tourigny JN, Tripathi M, Palmer JD, Matsui J, Crooks J, Wegner RE, Shepard MJ, Vance ML, Sheehan JP. PMID: 38095431; PMCID: PMC10995514.
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    22. Long-term radiographic and endocrinological outcomes of stereotactic radiosurgery for recurrent or residual nonfunctioning pituitary adenomas. J Neurosurg. 2024 Sep 01; 141(3):773-780. Shaaban A, Dumot C, Mantziaris G, Dayawansa S, Peker S, Samanci Y, Nabeel AM, Reda WA, Tawadros SR, Abdel Karim K, El-Shehaby AMN, Emad Eldin RM, Ragab Abdelsalam A, Liscak R, May J, Mashiach E, De Nigris Vasconcellos F, Bernstein K, Kondziolka D, Speckter H, Mota R, Brito A, Bindal SK, Niranjan A, Lunsford LD, Benjamin CG, Almeida T, Mao JZ, Mathieu D, Tourigny JN, Tripathi M, Palmer JD, Matsui J, Crooks J, Wegner RE, Shepard MJ, Sheehan JP. PMID: 38518285.
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    23. The relevance of biologically effective dose for pain relief and sensory dysfunction after Gamma Knife radiosurgery for trigeminal neuralgia: an 871-patient multicenter study. J Neurosurg. 2024 Aug 01; 141(2):461-473. Warnick RE, Paddick I, Mathieu D, Adam E, Iorio-Morin C, Leduc W, Hamel A, Johnson SE, Bydon M, Niranjan A, Lunsford LD, Wei Z, Waite K, Jose S, Peker S, Samanci MY, Tek E, Mantziaris G, Pikis S, Sheehan JP, Tripathi M, Kumar N, Alzate JD, Bernstein K, Ahorukomeye P, Kshettry VR, Speckter H, Hernandez W, Urgošík D, Lišcák R, Yang AI, Lee JYK, Patel S, Kusyk DM, Shepard MJ, Kondziolka D. PMID: 38364220.
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    24. Impact of Multiple Sclerosis Subtypes on Pain Management in Patients With Trigeminal Neuralgia After Stereotactic Radiosurgery: An International Multicenter Analysis. Neurosurgery. 2024 Apr 01; 94(4):838-846. De Nigris Vasconcellos F, Mashiach E, Alzate JD, Bernstein K, Rotman L, Levy S, Qu T, Wegner RE, Shepard MJ, Patel S, Warnick RE, Moreno NM, Martínez Álvarez R, Picozzi P, Franzini A, Peker S, Samanci Y, Elguindy AN, Palmer JD, Lunsford LD, Jose SG, Wei Z, Niranjan A, Blagui S, Iorio-Morin C, Mathieu D, Briggs RG, Yu C, Zada G, Dayawansa S, Sheehan J, Schulder M, Goenka A, Begley S, Khilji H, Urgošík D, Lišcák R, Kondziolka D. PMID: 38051068.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    25. Testicular ACE regulates sperm metabolism and fertilization through the transcription factor PPARγ. J Biol Chem. 2024 01; 300(1):105486. Shibata T, Bhat SA, Cao D, Saito S, Bernstein EA, Nishi E, Medenilla JD, Wang ET, Chan JL, Pisarska MD, Tourtellotte WG, Giani JF, Bernstein KE, Khan Z. PMID: 37992807; PMCID: PMC10788540.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    26. Diverse biological functions of the renin-angiotensin system. Med Res Rev. 2024 03; 44(2):587-605. Rao A, Bhat SA, Shibata T, Giani JF, Rader F, Bernstein KE, Khan Z. PMID: 37947345.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    27. Immune checkpoint inhibition and single fraction stereotactic radiosurgery in brain metastases from non-small cell lung cancer: an international multicenter study of 395 patients. J Neurooncol. 2023 Oct; 165(1):63-77. Lehrer EJ, Khosla AA, Ozair A, Gurewitz J, Bernstein K, Kondziolka D, Niranjan A, Wei Z, Lunsford LD, Mathieu D, Trudel C, Deibert CP, Malouff TD, Ruiz-Garcia H, Peterson JL, Patel S, Bonney P, Hwang L, Yu C, Zada G, Picozzi P, Franzini A, Attuati L, Prasad RN, Raval RR, Palmer JD, Lee CC, Yang HC, Fakhoury KR, Rusthoven CG, Dickstein DR, Sheehan JP, Trifiletti DM, Ahluwalia MS. PMID: 37889444.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    28. Myeloid cell ACE shapes cellular metabolism and function in PCSK-9 induced atherosclerosis. Front Immunol. 2023; 14:1278383. Cao D, Saito S, Xu L, Fan W, Li X, Ahmed F, Jovanovic P, Shibata T, Che M, Bernstein EA, Gianni J, Divakaruni AS, Okwan-Duodu D, Khan Z, Riera CE, Chen F, Bernstein KE. PMID: 37928535; PMCID: PMC10623052.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    29. Selected-Lesion Stereotactic Radiosurgery (SL-SRS) as a Novel Strategy in the Treatment of Patients With Multiple Brain Metastases. Cureus. 2023 Sep; 15(9):e45457. Theriault BC, Singh C, Yu J, Knisely J, Shepard M, Wegner RE, Warnick RE, Peker S, Samanci Y, Trifiletti DM, Lee CC, Yang HC, Bernstein K, Kondziolka D, Tripathi M, Mathieu D, Mantziaris G, Pikis S, Sheehan J, Chiang VL. PMID: 37859877; PMCID: PMC10583225.
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    30. Macrophage angiotensin-converting enzyme reduces atherosclerosis by increasing peroxisome proliferator-activated receptor α and fundamentally changing lipid metabolism. Cardiovasc Res. 2023 08 07; 119(9):1825-1841. Cao D, Khan Z, Li X, Saito S, Bernstein EA, Victor AR, Ahmed F, Hoshi AO, Veiras LC, Shibata T, Che M, Cai L, Temel RE, Giani JF, Luthringer DJ, Divakaruni AS, Okwan-Duodu D, Bernstein KE. PMID: 37225143; PMCID: PMC10681664.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    31. The effects of enhancing angiotensin converting enzyme in myelomonocytes on ameliorating Alzheimer's-related disease and preserving cognition. Front Physiol. 2023; 14:1179315. Danziger R, Fuchs DT, Koronyo Y, Rentsendorj A, Sheyn J, Hayden EY, Teplow DB, Black KL, Fuchs S, Bernstein KE, Koronyo-Hamaoui M. PMID: 37427403; PMCID: PMC10326285.
      View in: PubMed   Mentions: 4  
    32. Stereotactic Radiosurgery for Meningiomas in Children and Adolescents: An International Multi-Institutional Study. Neurosurgery. 2023 11 01; 93(5):1066-1074. Samanci Y, Askeroglu MO, Nabeel AM, Reda WA, Tawadros SR, Abdelkarim K, El-Shehaby AMN, Emad RM, Legarreta A, Fernandes Cabral D, Anand S, Niranjan A, Lunsford LD, Tripathi M, Kumar N, Lišcák R, May J, Lee CC, Yang HC, Martínez Moreno N, Martínez Álvarez R, Douri K, Mathieu D, Pikis S, Mantziaris G, Sheehan JP, Bernstein K, Kondziolka D, Peker S. PMID: 37235980.
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    33. Adjuvant Stereotactic Radiosurgery With or Without Postresection Fractionated Radiation Therapy for the Management of Clival Chordomas in Adults: An International Multicenter Case Series. Neurosurgery. 2023 10 01; 93(4):892-900. Bin-Alamer O, Pikis S, Mantziaris G, Abdulbaki A, Mallela AN, Lu VM, Peker S, Samanci Y, Nabeel AM, Reda WA, Tawadros SR, El-Shehaby AMN, Abdelkarim K, Emad Eldin RM, Sheehan D, Sheehan K, Liscak R, Chytka T, Tripathi M, Madan R, Speckter H, Hernández W, Barnett GH, Hori YS, Dabhi N, Aldakhil S, Mathieu D, Kondziolka D, Bernstein K, Wei Z, Niranjan A, Kersh CR, Lunsford LD, Sheehan JP, Abou-Al-Shaar H. PMID: 37052386.
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    34. Concurrent Administration of Immune Checkpoint Inhibitors and Single Fraction Stereotactic Radiosurgery in Patients With Non-Small Cell Lung Cancer, Melanoma, and Renal Cell Carcinoma Brain Metastases. Int J Radiat Oncol Biol Phys. 2023 Jul 15; 116(4):858-868. Lehrer EJ, Kowalchuk RO, Gurewitz J, Bernstein K, Kondziolka D, Niranjan A, Wei Z, Lunsford LD, Fakhoury KR, Rusthoven CG, Mathieu D, Trudel C, Malouff TD, Ruiz-Garcia H, Bonney P, Hwang L, Yu C, Zada G, Patel S, Deibert CP, Picozzi P, Franzini A, Attuati L, Prasad RN, Raval RR, Palmer JD, Lee CC, Yang HC, Harmsen WS, Jones BM, Sharma S, Ahluwalia MS, Sheehan JP, Trifiletti DM. PMID: 36690161.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    35. Effects of Neuroanatomic Structural Distances on Pituitary Function After Stereotactic Radiosurgery: A Multicenter Study. Neurosurgery. 2023 05 01; 92(5):1035-1042. Ironside N, Chen CJ, Xu Z, Schlesinger D, Lee Vance M, Hong GK, Jane JA, Patel S, Bindal SK, Niranjan A, Lunsford LD, Liscak R, Chytka T, Jezkova J, Saifi O, Trifiletti DM, Berger A, Alzate J, Bernstein K, Kondziolka D, Speckter H, Hernandez W, Lazo E, Peker S, Samanci Y, Zacharia BE, Mau C, Wegner RE, Shepard MJ, Mathieu D, Maillet M, Sheehan JP. PMID: 36700741.
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    36. Single-cell profiling identifies ACE+ granuloma macrophages as a nonpermissive niche for intracellular bacteria during persistent Salmonella infection. Sci Adv. 2023 01 06; 9(1):eadd4333. Pham THM, Xue Y, Brewer SM, Bernstein KE, Quake SR, Monack DM. PMID: 36608122; PMCID: PMC9821941.
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    37. Stereotactic Radiosurgery for Intraventricular Metastases: A Multicenter Study. Neurosurgery. 2023 03 01; 92(3):565-573. Mantziaris G, Pikis S, Xu Z, Mullen R, Alzate J, Bernstein K, Kondziolka D, Wei Z, Niranjan A, Lunsford LD, Liscak R, May J, Lee CC, Yang HC, Coupé FL, Mathieu D, Sheehan K, Sheehan D, Palmer JD, Perlow HK, Peker S, Samanci Y, Peterson J, Trifiletti DM, Shepard MJ, Elhamdani S, Wegner RE, Speckter H, Hernandez W, Warnick RE, Sheehan J. PMID: 36512817.
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    38. Knockout of ACE-N facilitates improved cardiac function after myocardial infarction. J Mol Cell Cardiol Plus. 2023 Mar; 3. Suhail H, Peng H, Xu J, Sabbah HN, Matrougui K, Liao TD, Ortiz PA, Bernstein KE, Rhaleb NE. PMID: 36778784; PMCID: PMC9910327.
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    39. miR766-3p and miR124-3p Dictate Drug Resistance and Clinical Outcome in HNSCC. Cancers (Basel). 2022 Oct 27; 14(21). Shibata T, Cao DY, Dar TB, Ahmed F, Bhat SA, Veiras LC, Bernstein EA, Khan AA, Chaum M, Shiao SL, Tourtellotte WG, Giani JF, Bernstein KE, Cui X, Vail E, Khan Z. PMID: 36358691; PMCID: PMC9655574.
      View in: PubMed   Mentions: 4  
    40. Concurrent Administration of Immune Checkpoint Inhibitors and Stereotactic Radiosurgery Is Well-Tolerated in Patients With Melanoma Brain Metastases: An International Multicenter Study of 203 Patients. Neurosurgery. 2022 12 01; 91(6):872-882. Lehrer EJ, Gurewitz J, Bernstein K, Kondziolka D, Fakhoury KR, Rusthoven CG, Niranjan A, Wei Z, Lunsford LD, Malouff TD, Ruiz-Garcia H, Peterson JL, Bonney P, Hwang L, Yu C, Zada G, Deibert CP, Prasad RN, Raval RR, Palmer JD, Patel S, Picozzi P, Franzini A, Attuati L, Mathieu D, Trudel C, Lee CC, Yang HC, Jones BM, Green S, Ahluwalia MS, Sheehan JP, Trifiletti DM. PMID: 36255215.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansPHPublic Health
    41. Imaging-defined necrosis after treatment with single-fraction stereotactic radiosurgery and immune checkpoint inhibitors and its potential association with improved outcomes in patients with brain metastases: an international multicenter study of 697 patients. J Neurosurg. 2023 05 01; 138(5):1178-1187. Lehrer EJ, Ahluwalia MS, Gurewitz J, Bernstein K, Kondziolka D, Niranjan A, Wei Z, Lunsford LD, Fakhoury KR, Rusthoven CG, Mathieu D, Trudel C, Malouff TD, Ruiz-Garcia H, Bonney P, Hwang L, Yu C, Zada G, Patel S, Deibert CP, Picozzi P, Franzini A, Attuati L, Prasad RN, Raval RR, Palmer JD, Lee CC, Yang HC, Jones BM, Green S, Sheehan JP, Trifiletti DM. PMID: 36115055.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    42. Overexpressed angiotensin-converting enzyme in neutrophils suppresses glomerular damage in crescentic glomerulonephritis. Am J Physiol Renal Physiol. 2022 10 01; 323(4):F411-F424. Saito S, Tatsumoto N, Cao DY, Nosaka N, Nishi H, Leal DN, Bernstein E, Shimada K, Arditi M, Bernstein KE, Yamashita M. PMID: 35979968; PMCID: PMC9484997.
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    43. Tubular IL-1β Induces Salt Sensitivity in Diabetes by Activating Renal Macrophages. Circ Res. 2022 06 24; 131(1):59-73. Veiras LC, Bernstein EA, Cao D, Okwan-Duodu D, Khan Z, Gibb DR, Roach A, Skelton R, Williams RM, Bernstein KE, Giani JF. PMID: 35574842; PMCID: PMC9233055.
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    44. Stereotactic radiosurgery for the treatment of hypoglossal schwannoma: a multi-institutional retrospective study. Acta Neurochir (Wien). 2022 09; 164(9):2473-2481. Dabhi N, Pikis S, Mantziaris G, Tripathi M, Warnick R, Peker S, Samanci Y, Berger A, Bernstein K, Kondziolka D, Niranjan A, Lunsford LD, Sheehan JP. PMID: 35347448.
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    45. Stereotactic Radiosurgery Compared With Active Surveillance for Asymptomatic, Parafalcine, and Parasagittal Meningiomas: A Matched Cohort Analysis From the IMPASSE Study. Neurosurgery. 2022 06 01; 90(6):750-757. Pikis S, Mantziaris G, Bunevicius A, Islim AI, Peker S, Samanci Y, Nabeel AM, Reda WA, Tawadros SR, El-Shehaby AMN, Abdelkarim K, Emad RM, Delabar V, Mathieu D, Lee CC, Yang HC, Liscak R, May J, Alvarez RM, Patel DN, Kondziolka D, Bernstein K, Moreno NM, Tripathi M, Speckter H, Albert C, Bowden GN, Benveniste RJ, Lunsford LD, Jenkinson MD, Sheehan J. PMID: 35319529.
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    46. The non-cardiovascular actions of ACE. Peptides. 2022 06; 152:170769. Cao D, Veiras L, Ahmed F, Shibata T, Bernstein EA, Okwan-Duodu D, Giani JF, Khan Z, Bernstein KE. PMID: 35182689; PMCID: PMC10405936.
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    47. Stereotactic radiosurgery for Rathke's cleft cysts: an international multicenter study. J Neurosurg. 2022 Oct 01; 137(4):1041-1046. Kondziolka D, Bernstein K, Lee CC, Yang HC, Liscak R, May J, Martínez-Álvarez R, Martínez-Moreno N, Bunevicius A, Sheehan JP. PMID: 35148508.
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    48. Stereotactic radiosurgery for intracranial chordomas: an international multiinstitutional study. J Neurosurg. 2022 Oct 01; 137(4):977-984. Pikis S, Mantziaris G, Peker S, Samanci Y, Nabeel AM, Reda WA, Tawadros SR, El-Shehaby AMN, Abdelkarim K, Eldin RME, Sheehan D, Sheehan K, Liscak R, Chytka T, Tripathi M, Madan R, Speckter H, Hernández W, Barnett GH, Hori YS, Dabhi N, Aldakhil S, Mathieu D, Kondziolka D, Bernstein K, Wei Z, Niranjan A, Kersh CR, Lunsford LD, Sheehan JP. PMID: 35120328.
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    49. Radiation necrosis in renal cell carcinoma brain metastases treated with checkpoint inhibitors and radiosurgery: An international multicenter study. Cancer. 2022 04 01; 128(7):1429-1438. Lehrer EJ, Gurewitz J, Bernstein K, Patel D, Kondziolka D, Niranjan A, Wei Z, Lunsford LD, Malouff TD, Ruiz-Garcia H, Patel S, Bonney PA, Hwang L, Yu C, Zada G, Mathieu D, Trudel C, Prasad RN, Palmer JD, Jones BM, Sharma S, Fakhoury KR, Rusthoven CG, Deibert CP, Picozzi P, Franzini A, Attuati L, Lee CC, Yang HC, Ahluwalia MS, Sheehan JP, Trifiletti DM. PMID: 35077586.
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    50. Stereotactic radiosurgery versus active surveillance for asymptomatic, skull-based meningiomas: an international, multicenter matched cohort study. J Neurooncol. 2022 Feb; 156(3):509-518. Mantziaris G, Pikis S, Samanci Y, Peker S, Nabeel AM, Reda WA, Tawadros SR, El-Shehaby AMN, Abdelkarim K, Emad RM, Delabar V, Mathieu D, Lee CC, Yang HC, Liscak R, Hanuska J, Alvarez RM, Moreno NM, Tripathi M, Speckter H, Albert C, Benveniste RJ, Bowden GN, Patel DN, Kondziolka D, Bernstein K, Lunsford LD, Jenkinson MD, Islim AI, Sheehan J. PMID: 35067846.
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    51. Stereotactic radiosurgery for IDH wild type glioblastoma: an international, multicenter study. J Neurooncol. 2021 Dec; 155(3):343-351. Bunevicius A, Pikis S, Kondziolka D, Patel DN, Bernstein K, Sulman EP, Lee CC, Yang HC, Delabar V, Mathieu D, Cifarelli CP, Arsanious DE, Dahshan BA, Weir JS, Speckter H, Mota A, Tripathi M, Kumar N, Warnick RE, Peker S, Samanci Y, Barnett G, Hefnawi FE, Al Sideiri G, Sheehan J. PMID: 34797526.
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    52. Stereotactic radiosurgery for asymptomatic petroclival region meningiomas: a focused analysis from the IMPASSE study. Acta Neurochir (Wien). 2022 01; 164(1):273-279. Mantziaris G, Pikis S, Bunevicius A, Peker S, Samanci Y, Nabeel AM, Reda WA, Tawadros SR, El-Shehaby AMN, Abdelkarim K, Emad RM, Delabar V, Mathieu D, Lee CC, Yang HC, Liscak R, Hanuska J, Alvarez RM, Moreno NM, Tripathi M, Speckter H, Albert C, Bowden GN, Benveniste RJ, Patel DN, Kondziolka D, Bernstein K, Lunsford LD, Sheehan J. PMID: 34767093.
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    53. Stereotactic radiosurgery for glioblastoma considering tumor genetic profiles: an international multicenter study. J Neurosurg. 2022 Jul 01; 137(1):42-50. Bunevicius A, Pikis S, Kondziolka D, Patel DN, Bernstein K, Sulman EP, Lee CC, Yang HC, Delabar V, Mathieu D, Cifarelli CP, Arsanious DE, Dahshan BA, Weir JS, Speckter H, Mota A, Tripathi M, Kumar N, Warnick RE, Sheehan JP. PMID: 34740186.
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    54. Stereotactic radiosurgery for prostate cancer cerebral metastases: an international multicenter study. J Neurosurg. 2022 May 01; 136(5):1307-1313. Pikis S, Bunevicius A, Lee CC, Yang HC, Zacharia BE, Lišcák R, Simonova G, Tripathi M, Kumar N, Mathieu D, Perron R, Peker S, Samanci Y, Gurewitz J, Bernstein K, Kondziolka D, Niranjan A, Lunsford LD, Mantziaris N, Sheehan JP. PMID: 34598139.
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    55. Dose to neuroanatomical structures surrounding pituitary adenomas and the effect of stereotactic radiosurgery on neuroendocrine function: an international multicenter study. J Neurosurg. 2022 Mar 01; 136(3):813-821. Pomeraniec IJ, Xu Z, Lee CC, Yang HC, Chytka T, Liscak R, Martinez-Alvarez R, Martinez-Moreno N, Attuati L, Picozzi P, Kondziolka D, Mureb M, Bernstein K, Mathieu D, Maillet M, Ogino A, Long H, Kano H, Lunsford LD, Zacharia BE, Mau C, Tuanquin LC, Cifarelli C, Arsanious D, Hack J, Warnick RE, Strickland BA, Zada G, Chang EL, Speckter H, Patel S, Ding D, Sheehan D, Sheehan K, Kvint S, Buch LY, Haber AR, Shteinhart J, Vance ML, Sheehan JP. PMID: 34560630.
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    56. An ACE inhibitor reduces bactericidal activity of human neutrophils in vitro and impairs mouse neutrophil activity in vivo. Sci Transl Med. 2021 07 28; 13(604). Cao DY, Giani JF, Veiras LC, Bernstein EA, Okwan-Duodu D, Ahmed F, Bresee C, Tourtellotte WG, Karumanchi SA, Bernstein KE, Khan Z. PMID: 34321319; PMCID: PMC10370421.
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    57. Local and downstream actions of proximal tubule angiotensin II signaling on Na+ transporters in the mouse nephron. Am J Physiol Renal Physiol. 2021 07 01; 321(1):F69-F81. Nelson JW, McDonough AA, Xiang Z, Ralph DL, Robertson JA, Giani JF, Bernstein KE, Gurley SB. PMID: 34056928; PMCID: PMC8321806.
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    58. Stereotactic Radiosurgery for Differentiated Thyroid Cancer Brain Metastases: An International, Multicenter Study. Thyroid. 2021 08; 31(8):1244-1252. Bunevicius A, Fribance S, Pikis S, Lee JYK, Buch LY, Moran M, Yang AI, Bernstein K, Mathieu D, Perron R, Liscak R, Simonova G, Patel S, Trifiletti DM, Martínez Álvarez R, Martínez Moreno N, Lee CC, Yang HC, Strickland BA, Zada G, Chang EL, Kondziolka D, Sheehan J. PMID: 33978475.
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    59. Stereotactic Radiosurgery for Atypical (World Health Organization II) and Anaplastic (World Health Organization III) Meningiomas: Results From a Multicenter, International Cohort Study. Neurosurgery. 2021 04 15; 88(5):980-988. Shepard MJ, Xu Z, Kearns K, Li C, Chatrath A, Sheehan K, Sheehan D, Faramand A, Niranjan A, Kano H, Gurewitz J, Bernstein K, Liscak R, Guseynova K, Grills IS, Parzen JS, Cifarelli CP, Rehman AA, Atik A, Bakhsheshian J, Zada G, Chang E, Giannotta S, Speckter H, Wu HM, Kondziolka D, Golfinos JG, Mathieu D, Lee CC, Warnick RE, Lunsford LD, Sheehan JP. PMID: 33469655.
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    60. Novel roles of the renal angiotensin-converting enzyme. Mol Cell Endocrinol. 2021 06 01; 529:111257. Giani JF, Veiras LC, Shen JZY, Bernstein EA, Cao D, Okwan-Duodu D, Khan Z, Gonzalez-Villalobos RA, Bernstein KE. PMID: 33781839; PMCID: PMC8127398.
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    61. Renal Inflammation Induces Salt Sensitivity in Male db/db Mice through Dysregulation of ENaC. J Am Soc Nephrol. 2021 05 03; 32(5):1131-1149. Veiras LC, Shen JZY, Bernstein EA, Regis GC, Cao D, Okwan-Duodu D, Khan Z, Gibb DR, Dominici FP, Bernstein KE, Giani JF. PMID: 33731332; PMCID: PMC8259671.
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    62. Treatment of WHO Grade 2 Meningiomas With Stereotactic Radiosurgery: Identification of an Optimal Group for SRS Using RPA. Int J Radiat Oncol Biol Phys. 2021 Jul 01; 110(3):804-814. Kowalchuk RO, Shepard MJ, Sheehan K, Sheehan D, Faramand A, Niranjan A, Kano H, Gurewitz J, Bernstein K, Liscak R, Guseynova K, Grills IS, Parzen JS, Cifarelli CP, Rehman AA, Atik A, Bakhsheshian J, Zada G, Chang E, Giannotta S, Speckter H, Wu HM, Kondziolka D, Mathieu D, Lee CC, Warnick RE, Lunsford LD, Trifiletti DM, Sheehan JP. PMID: 33548341.
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    63. Tumors exploit CXCR4hiCD62Llo aged neutrophils to facilitate metastatic spread. Oncoimmunology. 2021 01 20; 10(1):1870811. Peng Z, Liu C, Victor AR, Cao DY, Veiras LC, Bernstein EA, Khan Z, Giani JF, Cui X, Bernstein KE, Okwan-Duodu D. PMID: 33537175; PMCID: PMC7833766.
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    64. Effect of Anatomic Segment Involvement on Stereotactic Radiosurgery for Facial Nerve Schwannomas: An International Multicenter Cohort Study. Neurosurgery. 2020 12 15; 88(1):E91-E98. Mehta GU, Lekovic GP, Slattery WH, Brackmann DE, Long H, Kano H, Kondziolka D, Mureb M, Bernstein K, Langlois AM, Mathieu D, Nabeel AM, Reda WA, Tawadros SR, Abdelkarim K, El-Shehaby AMN, Emad RM, Mohammed N, Urgosik D, Liscak R, Lee CC, Yang HC, Montazeripouragha A, Kaufmann AM, Joshi KC, Barnett GH, Trifiletti DM, Lunsford LD, Sheehan JP. PMID: 32687577.
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    65. Vascular contributions to cognitive impairment and dementia (VCID): A report from the 2018 National Heart, Lung, and Blood Institute and National Institute of Neurological Disorders and Stroke Workshop. Alzheimers Dement. 2020 12; 16(12):1714-1733. Zlokovic BV, Gottesman RF, Bernstein KE, Seshadri S, McKee A, Snyder H, Greenberg SM, Yaffe K, Schaffer CB, Yuan C, Hughes TM, Daemen MJ, Williamson JD, González HM, Schneider J, Wellington CL, Katusic ZS, Stoeckel L, Koenig JI, Corriveau RA, Fine L, Galis ZS, Reis J, Wright JD, Chen J. PMID: 33030307.
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    66. Activation of AT2 receptors prevents diabetic complications in female db/db mice by NO-mediated mechanisms. Br J Pharmacol. 2020 10; 177(20):4766-4781. Dominici FP, Veiras LC, Shen JZY, Bernstein EA, Quiroga DT, Steckelings UM, Bernstein KE, Giani JF. PMID: 32851652; PMCID: PMC7520448.
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    67. Role of angiotensin-converting enzyme in myeloid cell immune responses. Cell Mol Biol Lett. 2020; 25:31. Cao DY, Saito S, Veiras LC, Okwan-Duodu D, Bernstein EA, Giani JF, Bernstein KE, Khan Z. PMID: 32508938; PMCID: PMC7249647.
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    68. Overexpression of ACE in Myeloid Cells Increases Immune Effectiveness and Leads to a New Way of Considering Inflammation in Acute and Chronic Diseases. Curr Hypertens Rep. 2020 01 08; 22(1):4. Veiras LC, Cao D, Saito S, Peng Z, Bernstein EA, Shen JZY, Koronyo-Hamaoui M, Okwan-Duodu D, Giani JF, Khan Z, Bernstein KE. PMID: 31916032; PMCID: PMC7213017.
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    69. Peripherally derived angiotensin converting enzyme-enhanced macrophages alleviate Alzheimer-related disease. Brain. 2020 01 01; 143(1):336-358. Koronyo-Hamaoui M, Sheyn J, Hayden EY, Li S, Fuchs DT, Regis GC, Lopes DHJ, Black KL, Bernstein KE, Teplow DB, Fuchs S, Koronyo Y, Rentsendorj A. PMID: 31794021; PMCID: PMC6935752.
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    70. ACE overexpression in myeloid cells increases oxidative metabolism and cellular ATP. J Biol Chem. 2020 01 31; 295(5):1369-1384. Cao DY, Spivia WR, Veiras LC, Khan Z, Peng Z, Jones AE, Bernstein EA, Saito S, Okwan-Duodu D, Parker SJ, Giani JF, Divakaruni AS, Van Eyk JE, Bernstein KE. PMID: 31871049; PMCID: PMC6996878.
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    71. Overexpression of myeloid angiotensin-converting enzyme (ACE) reduces atherosclerosis. Biochem Biophys Res Commun. 2019 12 10; 520(3):573-579. Okwan-Duodu D, Weiss D, Peng Z, Veiras LC, Cao DY, Saito S, Khan Z, Bernstein EA, Giani JF, Taylor WR, Bernstein KE. PMID: 31615657; PMCID: PMC6916669.
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    72. ATP release drives heightened immune responses associated with hypertension. Sci Immunol. 2019 06 28; 4(36). Zhao TV, Li Y, Liu X, Xia S, Shi P, Li L, Chen Z, Yin C, Eriguchi M, Chen Y, Bernstein EA, Giani JF, Bernstein KE, Shen XZ. PMID: 31253642; PMCID: PMC6699629.
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    73. The Plethora of Angiotensin-Converting Enzyme-Processed Peptides in Mouse Plasma. Anal Chem. 2019 05 21; 91(10):6440-6453. Semis M, Gugiu GB, Bernstein EA, Bernstein KE, Kalkum M. PMID: 31021607; PMCID: PMC6693507.
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    74. Overexpression of the C-domain of angiotensin-converting enzyme reduces melanoma growth by stimulating M1 macrophage polarization. J Biol Chem. 2019 03 22; 294(12):4368-4380. Khan Z, Cao DY, Giani JF, Bernstein EA, Veiras LC, Fuchs S, Wang Y, Peng Z, Kalkum M, Liu GY, Bernstein KE. PMID: 30670595; PMCID: PMC6433053.
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    75. Angiotensin-converting enzyme inhibitor works as a scar formation inhibitor by down-regulating Smad and TGF-β-activated kinase 1 (TAK1) pathways in mice. Br J Pharmacol. 2018 11; 175(22):4239-4252. Tan WQ, Fang QQ, Shen XZ, Giani JF, Zhao TV, Shi P, Zhang LY, Khan Z, Li Y, Li L, Xu JH, Bernstein EA, Bernstein KE. PMID: 30153328; PMCID: PMC6193878.
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    76. The Absence of the ACE N-Domain Decreases Renal Inflammation and Facilitates Sodium Excretion during Diabetic Kidney Disease. J Am Soc Nephrol. 2018 10; 29(10):2546-2561. Eriguchi M, Bernstein EA, Veiras LC, Khan Z, Cao DY, Fuchs S, McDonough AA, Toblli JE, Gonzalez-Villalobos RA, Bernstein KE, Giani JF. PMID: 30185469; PMCID: PMC6171283.
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    77. Angiotensin-converting enzyme in innate and adaptive immunity. Nat Rev Nephrol. 2018 05; 14(5):325-336. Bernstein KE, Khan Z, Giani JF, Cao DY, Bernstein EA, Shen XZ. PMID: 29578208; PMCID: PMC6192041.
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    78. Renal tubular ACE-mediated tubular injury is the major contributor to microalbuminuria in early diabetic nephropathy. Am J Physiol Renal Physiol. 2018 04 01; 314(4):F531-F542. Eriguchi M, Lin M, Yamashita M, Zhao TV, Khan Z, Bernstein EA, Gurley SB, Gonzalez-Villalobos RA, Bernstein KE, Giani JF. PMID: 29187372; PMCID: PMC5966765.
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    79. Angiotensin-converting enzyme defines matrikine-regulated inflammation and fibrosis. JCI Insight. 2017 11 16; 2(22). O'Reilly PJ, Ding Q, Akthar S, Cai G, Genschmer KR, Patel DF, Jackson PL, Viera L, Roda M, Locy ML, Bernstein EA, Lloyd CM, Bernstein KE, Snelgrove RJ, Blalock JE. PMID: 29202450; PMCID: PMC5752376.
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    80. Brain Transforming Growth Factor-β Resists Hypertension Via Regulating Microglial Activation. Stroke. 2017 09; 48(9):2557-2564. Li Y, Shen XZ, Li L, Zhao TV, Bernstein KE, Johnson AK, Lyden P, Fang J, Shi P. PMID: 28698257; PMCID: PMC5575981.
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    81. Angiotensin-converting enzyme enhances the oxidative response and bactericidal activity of neutrophils. Blood. 2017 07 20; 130(3):328-339. Khan Z, Shen XZ, Bernstein EA, Giani JF, Eriguchi M, Zhao TV, Gonzalez-Villalobos RA, Fuchs S, Liu GY, Bernstein KE. PMID: 28515091; PMCID: PMC5520468.
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    82. Angiotensin-converting enzyme affects the presentation of MHC class II antigens. Lab Invest. 2017 07; 97(7):764-771. Zhao T, Bernstein KE, Fang J, Shen XZ. PMID: 28394320; PMCID: PMC5493495.
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    83. Renal tubular angiotensin converting enzyme is responsible for nitro-L-arginine methyl ester (L-NAME)-induced salt sensitivity. Kidney Int. 2017 04; 91(4):856-867. Giani JF, Eriguchi M, Bernstein EA, Katsumata M, Shen XZ, Li L, McDonough AA, Fuchs S, Bernstein KE, Gonzalez-Villalobos RA. PMID: 27988209; PMCID: PMC5657384.
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    84. Overexpression of angiotensin-converting enzyme in myelomonocytic cells enhances the immune response. F1000Res. 2016; 5. Bernstein KE, Khan Z, Giani JF, Zhao T, Eriguchi M, Bernstein EA, Gonzalez-Villalobos RA, Shen XZ. PMID: 27018193; PMCID: PMC4806706.
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    85. CD70 Exacerbates Blood Pressure Elevation and Renal Damage in Response to Repeated Hypertensive Stimuli. Circ Res. 2016 Apr 15; 118(8):1233-43. Itani HA, Xiao L, Saleh MA, Wu J, Pilkinton MA, Dale BL, Barbaro NR, Foss JD, Kirabo A, Montaniel KR, Norlander AE, Chen W, Sato R, Navar LG, Mallal SA, Madhur MS, Bernstein KE, Harrison DG. PMID: 26988069; PMCID: PMC4833561.
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    86. Myeloid Suppressor Cells Accumulate and Regulate Blood Pressure in Hypertension. Circ Res. 2015 Oct 23; 117(10):858-69. Shah KH, Shi P, Giani JF, Janjulia T, Bernstein EA, Li Y, Zhao T, Harrison DG, Bernstein KE, Shen XZ. PMID: 26294657; PMCID: PMC4619122.
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    87. Salt Sensitivity in Response to Renal Injury Requires Renal Angiotensin-Converting Enzyme. Hypertension. 2015 Sep; 66(3):534-42. Giani JF, Bernstein KE, Janjulia T, Han J, Toblli JE, Shen XZ, Rodriguez-Iturbe B, McDonough AA, Gonzalez-Villalobos RA. PMID: 26150439; PMCID: PMC4825680.
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    88. Microglia participate in neurogenic regulation of hypertension. Hypertension. 2015 Aug; 66(2):309-16. Shen XZ, Li Y, Li L, Shah KH, Bernstein KE, Lyden P, Shi P. PMID: 26056339; PMCID: PMC4498964.
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    89. Angiotensin II receptor blockade or deletion of vascular endothelial ACE does not prevent vascular dysfunction and remodeling in 20-HETE-dependent hypertension. Am J Physiol Regul Integr Comp Physiol. 2015 Jul 01; 309(1):R71-8. Garcia V, Joseph G, Shkolnik B, Ding Y, Zhang FF, Gotlinger K, Falck JR, Dakarapu R, Capdevila JH, Bernstein KE, Schwartzman ML. PMID: 25924878; PMCID: PMC4491537.
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    90. The intrarenal generation of angiotensin II is required for experimental hypertension. Curr Opin Pharmacol. 2015 Apr; 21:73-81. Giani JF, Shah KH, Khan Z, Bernstein EA, Shen XZ, McDonough AA, Gonzalez-Villalobos RA, Bernstein KE. PMID: 25616034; PMCID: PMC4380835.
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    91. Angiotensin-converting enzyme overexpression in myelocytes enhances the immune response. Biol Chem. 2014 Oct; 395(10):1173-8. Bernstein KE, Gonzalez-Villalobos RA, Giani JF, Shah K, Bernstein E, Janjulia T, Koronyo Y, Shi PD, Koronyo-Hamaoui M, Fuchs S, Shen XZ. PMID: 24633750; PMCID: PMC4312006.
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    92. DC isoketal-modified proteins activate T cells and promote hypertension. J Clin Invest. 2014 Oct; 124(10):4642-56. Kirabo A, Fontana V, de Faria AP, Loperena R, Galindo CL, Wu J, Bikineyeva AT, Dikalov S, Xiao L, Chen W, Saleh MA, Trott DW, Itani HA, Vinh A, Amarnath V, Amarnath K, Guzik TJ, Bernstein KE, Shen XZ, Shyr Y, Chen SC, Mernaugh RL, Laffer CL, Elijovich F, Davies SS, Moreno H, Madhur MS, Roberts J, Harrison DG. PMID: 25244096; PMCID: PMC4220659.
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    93. Renal generation of angiotensin II and the pathogenesis of hypertension. Curr Hypertens Rep. 2014 Sep; 16(9):477. Giani JF, Janjulia T, Taylor B, Bernstein EA, Shah K, Shen XZ, McDonough AA, Bernstein KE, Gonzalez-Villalobos RA. PMID: 25097114; PMCID: PMC4277187.
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    94. Renal angiotensin-converting enzyme is essential for the hypertension induced by nitric oxide synthesis inhibition. J Am Soc Nephrol. 2014 Dec; 25(12):2752-63. Giani JF, Janjulia T, Kamat N, Seth DM, Blackwell WL, Shah KH, Shen XZ, Fuchs S, Delpire E, Toblli JE, Bernstein KE, McDonough AA, Gonzalez-Villalobos RA. PMID: 25012170; PMCID: PMC4243348.
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    95. ACE overexpression in myelomonocytic cells: effect on a mouse model of Alzheimer's disease. Curr Hypertens Rep. 2014 Jul; 16(7):444. Koronyo-Hamaoui M, Shah K, Koronyo Y, Bernstein E, Giani JF, Janjulia T, Black KL, Shi PD, Gonzalez-Villalobos RA, Fuchs S, Shen XZ, Bernstein KE. PMID: 24792094; PMCID: PMC4051235.
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    96. Myeloid expression of angiotensin-converting enzyme facilitates myeloid maturation and inhibits the development of myeloid-derived suppressor cells. Lab Invest. 2014 May; 94(5):536-44. Shen XZ, Okwan-Duodu D, Blackwell WL, Ong FS, Janjulia T, Bernstein EA, Fuchs S, Alkan S, Bernstein KE. PMID: 24614194; PMCID: PMC4221240.
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    97. Renal angiotensin-converting enzyme and blood pressure control. Curr Opin Nephrol Hypertens. 2014 Mar; 23(2):106-12. Bernstein KE, Giani JF, Shen XZ, Gonzalez-Villalobos RA. PMID: 24378774; PMCID: PMC4028050.
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    98. Angiotensin-converting enzyme overexpression in myelomonocytes prevents Alzheimer's-like cognitive decline. J Clin Invest. 2014 Mar; 124(3):1000-12. Bernstein KE, Koronyo Y, Salumbides BC, Sheyn J, Pelissier L, Lopes DH, Shah KH, Bernstein EA, Fuchs DT, Yu JJ, Pham M, Black KL, Shen XZ, Fuchs S, Koronyo-Hamaoui M. PMID: 24487585; PMCID: PMC3934162.
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    99. Rediscovering ACE: novel insights into the many roles of the angiotensin-converting enzyme. J Mol Med (Berl). 2013 Oct; 91(10):1143-54. Gonzalez-Villalobos RA, Shen XZ, Bernstein EA, Janjulia T, Taylor B, Giani JF, Blackwell WL, Shah KH, Shi PD, Fuchs S, Bernstein KE. PMID: 23686164; PMCID: PMC3779503.
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    100. The absence of intrarenal ACE protects against hypertension. J Clin Invest. 2013 May; 123(5):2011-23. Gonzalez-Villalobos RA, Janjoulia T, Fletcher NK, Giani JF, Nguyen MT, Riquier-Brison AD, Seth DM, Fuchs S, Eladari D, Picard N, Bachmann S, Delpire E, Peti-Peterdi J, Navar LG, Bernstein KE, McDonough AA. PMID: 23619363; PMCID: PMC3638907.
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    101. Identification of prolyl carboxypeptidase as an alternative enzyme for processing of renal angiotensin II using mass spectrometry. Am J Physiol Cell Physiol. 2013 May 15; 304(10):C945-53. Grobe N, Weir NM, Leiva O, Ong FS, Bernstein KE, Schmaier AH, Morris M, Elased KM. PMID: 23392115; PMCID: PMC3651643.
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    102. A modern understanding of the traditional and nontraditional biological functions of angiotensin-converting enzyme. Pharmacol Rev. 2013 Jan; 65(1):1-46. Bernstein KE, Ong FS, Blackwell WL, Shah KH, Giani JF, Gonzalez-Villalobos RA, Shen XZ, Fuchs S, Touyz RM. PMID: 23257181; PMCID: PMC3565918.
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    103. The M694V mutation in Armenian-Americans: a 10-year retrospective study of MEFV mutation testing for familial Mediterranean fever at UCLA. Clin Genet. 2013 Jul; 84(1):55-9. Ong FS, Vakil H, Xue Y, Kuo JZ, Shah KH, Lee RB, Bernstein KE, Rimoin DL, Getzug T, Das K, Deignan JL, Rotter JI, Grody WW. PMID: 23038988; PMCID: PMC3570680.
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    104. Personalized medicine and pharmacogenetic biomarkers: progress in molecular oncology testing. Expert Rev Mol Diagn. 2012 Jul; 12(6):593-602. Ong FS, Das K, Wang J, Vakil H, Kuo JZ, Blackwell WL, Lim SW, Goodarzi MO, Bernstein KE, Rotter JI, Grody WW. PMID: 22845480; PMCID: PMC3495985.
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    105. Clinical utility of pharmacogenetic biomarkers in cardiovascular therapeutics: a challenge for clinical implementation. Pharmacogenomics. 2012 Mar; 13(4):465-75. Ong FS, Deignan JL, Kuo JZ, Bernstein KE, Rotter JI, Grody WW, Das K. PMID: 22380001; PMCID: PMC3306231.
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    106. Nontraditional roles of angiotensin-converting enzyme. Hypertension. 2012 Apr; 59(4):763-8. Shen XZ, Ong FS, Bernstein EA, Janjulia T, Blackwell WL, Shah KH, Taylor BL, Gonzalez-Villalobos RA, Fuchs S, Bernstein KE. PMID: 22353608; PMCID: PMC3306543.
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    107. Increased angiotensin II-induced hypertension and inflammatory cytokines in mice lacking angiotensin-converting enzyme N domain activity. Hypertension. 2012 Feb; 59(2):283-90. Ong FS, Lin CX, Campbell DJ, Okwan-Duodu D, Chen X, Blackwell WL, Shah KH, Gonzalez-Villalobos RA, Shen XZ, Fuchs S, Bernstein KE. PMID: 22203735; PMCID: PMC3266456.
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    108. Inhibition of c-Src tyrosine kinase prevents angiotensin II-mediated connexin-43 remodeling and sudden cardiac death. J Am Coll Cardiol. 2011 Nov 22; 58(22):2332-9. Sovari AA, Iravanian S, Dolmatova E, Jiao Z, Liu H, Zandieh S, Kumar V, Wang K, Bernstein KE, Bonini MG, Duffy HS, Dudley SC. PMID: 22093512; PMCID: PMC3226807.
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    109. The carboxypeptidase ACE shapes the MHC class I peptide repertoire. Nat Immunol. 2011 Oct 02; 12(11):1078-85. Shen XZ, Billet S, Lin C, Okwan-Duodu D, Chen X, Lukacher AE, Bernstein KE. PMID: 21964607; PMCID: PMC3197883.
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    110. Inhibition of renin-angiotensin system (RAS) reduces ventricular tachycardia risk by altering connexin43. J Mol Med (Berl). 2011 Jul; 89(7):677-87. Iravanian S, Sovari AA, Lardin HA, Liu H, Xiao HD, Dolmatova E, Jiao Z, Harris BS, Witham EA, Gourdie RG, Duffy HS, Bernstein KE, Dudley SC. PMID: 21553032; PMCID: PMC3156477.
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    111. The peptide network regulated by angiotensin converting enzyme (ACE) in hematopoiesis. Cell Cycle. 2011 May 01; 10(9):1363-9. Shen XZ, Bernstein KE. PMID: 21441775; PMCID: PMC3117040.
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    112. Angiotensin-converting enzyme is required for normal myelopoiesis. FASEB J. 2011 Apr; 25(4):1145-55. Lin C, Datta V, Okwan-Duodu D, Chen X, Fuchs S, Alsabeh R, Billet S, Bernstein KE, Shen XZ. PMID: 21148418; PMCID: PMC3058713.
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    113. Different in vivo functions of the two catalytic domains of angiotensin-converting enzyme (ACE). Curr Opin Pharmacol. 2011 Apr; 11(2):105-11. Bernstein KE, Shen XZ, Gonzalez-Villalobos RA, Billet S, Okwan-Duodu D, Ong FS, Fuchs S. PMID: 21130035; PMCID: PMC3075415.
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    114. Intrarenal angiotensin-converting enzyme induces hypertension in response to angiotensin I infusion. J Am Soc Nephrol. 2011 Mar; 22(3):449-59. Gonzalez-Villalobos RA, Billet S, Kim C, Satou R, Fuchs S, Bernstein KE, Navar LG. PMID: 21115616; PMCID: PMC3060439.
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    115. Angiotensin-converting enzyme overexpression in mouse myelomonocytic cells augments resistance to Listeria and methicillin-resistant Staphylococcus aureus. J Biol Chem. 2010 Dec 10; 285(50):39051-60. Okwan-Duodu D, Datta V, Shen XZ, Goodridge HS, Bernstein EA, Fuchs S, Liu GY, Bernstein KE. PMID: 20937811; PMCID: PMC2998083.
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    116. Angiotensin-converting enzyme N-terminal inactivation alleviates bleomycin-induced lung injury. Am J Pathol. 2010 Sep; 177(3):1113-21. Li P, Xiao HD, Xu J, Ong FS, Kwon M, Roman J, Gal A, Bernstein KE, Fuchs S. PMID: 20651228; PMCID: PMC2928946.
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    117. Uncoupled cardiac nitric oxide synthase mediates diastolic dysfunction. Circulation. 2010 Feb 02; 121(4):519-28. Silberman GA, Fan TH, Liu H, Jiao Z, Xiao HD, Lovelock JD, Boulden BM, Widder J, Fredd S, Bernstein KE, Wolska BM, Dikalov S, Harrison DG, Dudley SC. PMID: 20083682; PMCID: PMC2819317.
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    118. New insights into the role of angiotensin-converting enzyme obtained from the analysis of genetically modified mice. J Mol Med (Berl). 2008 Jun; 86(6):679-84. Shen XZ, Xiao HD, Li P, Lin CX, Billet S, Okwan-Duodu D, Adams JW, Bernstein EA, Xu Y, Fuchs S, Bernstein KE. PMID: 18443752; PMCID: PMC6167991.
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    119. Expression of angiotensin-converting enzyme changes major histocompatibility complex class I peptide presentation by modifying C termini of peptide precursors. J Biol Chem. 2008 Apr 11; 283(15):9957-65. Shen XZ, Lukacher AE, Billet S, Williams IR, Bernstein KE. PMID: 18252713; PMCID: PMC2442301.
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    120. Tissue specific expression of angiotensin converting enzyme: a new way to study an old friend. Int Immunopharmacol. 2008 Feb; 8(2):171-6. Shen XZ, Xiao HD, Li P, Billet S, Lin CX, Fuchs S, Bernstein KE. PMID: 18182222; PMCID: PMC2247367.
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    121. Angiotensin-converting enzyme C-terminal catalytic domain is the main site of angiotensin I cleavage in vivo. Hypertension. 2008 Feb; 51(2):267-74. Fuchs S, Xiao HD, Hubert C, Michaud A, Campbell DJ, Adams JW, Capecchi MR, Corvol P, Bernstein KE. PMID: 18158355.
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    122. Mice expressing ACE only in the heart show that increased cardiac angiotensin II is not associated with cardiac hypertrophy. Am J Physiol Heart Circ Physiol. 2008 Feb; 294(2):H659-67. Xiao HD, Fuchs S, Bernstein EA, Li P, Campbell DJ, Bernstein KE. PMID: 18032521.
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    123. Gain-of-function mutant of angiotensin II receptor, type 1A, causes hypertension and cardiovascular fibrosis in mice. J Clin Invest. 2007 Jul; 117(7):1914-25. Billet S, Bardin S, Verp S, Baudrie V, Michaud A, Conchon S, Muffat-Joly M, Escoubet B, Souil E, Hamard G, Bernstein KE, Gasc JM, Elghozi JL, Corvol P, Clauser E. PMID: 17607364; PMCID: PMC1890996.
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    124. Mice with enhanced macrophage angiotensin-converting enzyme are resistant to melanoma. Am J Pathol. 2007 Jun; 170(6):2122-34. Shen XZ, Li P, Weiss D, Fuchs S, Xiao HD, Adams JA, Williams IR, Capecchi MR, Taylor WR, Bernstein KE. PMID: 17525278; PMCID: PMC1899454.
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    125. Is angiotensin II a direct mediator of left ventricular hypertrophy? Time for another look. Hypertension. 2007 Jun; 49(6):1196-201. Reudelhuber TL, Bernstein KE, Delafontaine P. PMID: 17452509; PMCID: PMC3227117.
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    126. Cardiac-restricted angiotensin-converting enzyme overexpression causes conduction defects and connexin dysregulation. Am J Physiol Heart Circ Physiol. 2007 Jul; 293(1):H182-92. Kasi VS, Xiao HD, Shang LL, Iravanian S, Langberg J, Witham EA, Jiao Z, Gallego CJ, Bernstein KE, Dudley SC. PMID: 17337599; PMCID: PMC3160110.
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    127. Regulation of steady-state beta-amyloid levels in the brain by neprilysin and endothelin-converting enzyme but not angiotensin-converting enzyme. J Biol Chem. 2006 Oct 13; 281(41):30471-8. Eckman EA, Adams SK, Troendle FJ, Stodola BA, Kahn MA, Fauq AH, Xiao HD, Bernstein KE, Eckman CB. PMID: 16912050.
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    128. ACE and ACE2 activity in diabetic mice. Diabetes. 2006 Jul; 55(7):2132-9. Wysocki J, Ye M, Soler MJ, Gurley SB, Xiao HD, Bernstein KE, Coffman TM, Chen S, Batlle D. PMID: 16804085.
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    129. Views of the renin-angiotensin system: brilling, mimsy, and slithy tove. Hypertension. 2006 Mar; 47(3):509-14. Bernstein KE. PMID: 16365193.
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    130. Six truisms concerning ACE and the renin-angiotensin system educed from the genetic analysis of mice. Circ Res. 2005 Jun 10; 96(11):1135-44. Bernstein KE, Xiao HD, Frenzel K, Li P, Shen XZ, Adams JW, Fuchs S. PMID: 15947253.
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    131. Angiotensin II-induced hypertension in mice caused an increase in insulin secretion. Vascul Pharmacol. 2005 Feb; 42(3):83-92. Gletsu N, Doan TN, Cole J, Sutliff RL, Bernstein KE. PMID: 15792925.
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    132. Establishing the role of angiotensin-converting enzyme in renal function and blood pressure control through the analysis of genetically modified mice. J Am Soc Nephrol. 2005 Mar; 16(3):583-91. Bernstein KE, Xiao HD, Adams JW, Frenzel K, Li P, Shen XZ, Cole JM, Fuchs S. PMID: 15659560.
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    133. Micropuncture determination of nephron function in mice without tissue angiotensin-converting enzyme. Am J Physiol Renal Physiol. 2005 Mar; 288(3):F445-52. Hashimoto S, Adams JW, Bernstein KE, Schnermann J. PMID: 15494545.
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    134. Mice with cardiac-restricted angiotensin-converting enzyme (ACE) have atrial enlargement, cardiac arrhythmia, and sudden death. Am J Pathol. 2004 Sep; 165(3):1019-32. Xiao HD, Fuchs S, Campbell DJ, Lewis W, Dudley SC, Kasi VS, Hoit BD, Keshelava G, Zhao H, Capecchi MR, Bernstein KE. PMID: 15331425; PMCID: PMC1618615.
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    135. The use of knockout mouse technology to achieve tissue selective expression of angiotensin converting enzyme. J Mol Cell Cardiol. 2004 Jun; 36(6):781-9. Xiao HD, Fuchs S, Frenzel K, Teng L, Li P, Shen XZ, Adams J, Zhao H, Keshelava GT, Bernstein KE, Cole JM. PMID: 15158118.
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    136. Newly recognized physiologic and pathophysiologic actions of the angiotensin-converting enzyme. Curr Hypertens Rep. 2004 Apr; 6(2):124-8. Fuchs S, Frenzel K, Xiao HD, Adams JW, Zhao H, Keshelava G, Teng L, Bernstein KE. PMID: 15010016.
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    137. Depletion of tissue angiotensin-converting enzyme differentially influences the intrarenal and urinary expression of angiotensin peptides. Hypertension. 2004 Apr; 43(4):849-53. Modrall JG, Sadjadi J, Brosnihan KB, Gallagher PE, Yu CH, Kramer GL, Bernstein KE, Chappell MC. PMID: 14981053.
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    138. Effect of reduced angiotensin-converting enzyme gene expression and angiotensin-converting enzyme inhibition on angiotensin and bradykinin peptide levels in mice. Hypertension. 2004 Apr; 43(4):854-9. Campbell DJ, Alexiou T, Xiao HD, Fuchs S, McKinley MJ, Corvol P, Bernstein KE. PMID: 14769811.
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    139. Role of the N-terminal catalytic domain of angiotensin-converting enzyme investigated by targeted inactivation in mice. J Biol Chem. 2004 Apr 16; 279(16):15946-53. Fuchs S, Xiao HD, Cole JM, Adams JW, Frenzel K, Michaud A, Zhao H, Keshelava G, Capecchi MR, Corvol P, Bernstein KE. PMID: 14757757.
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    140. Circulating versus local angiotensin II in blood pressure control: lessons from tissue-specific expression of angiotensin-converting enzyme (ACE). Crit Rev Eukaryot Gene Expr. 2004; 14(1-2):137-45. Xiao HD, Fuchs S, Frenzel K, Teng L, Bernstein KE. PMID: 15104531.
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    141. Newer approaches to genetic modeling in mice: tissue-specific protein expression as studied using angiotensin-converting enzyme (ACE). Am J Pathol. 2003 Sep; 163(3):807-17. Xiao HD, Fuchs S, Frenzel K, Cole JM, Bernstein KE. PMID: 12937122; PMCID: PMC1868276.
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    142. New approaches to genetic manipulation of mice: tissue-specific expression of ACE. Am J Physiol Renal Physiol. 2003 Apr; 284(4):F599-607. Cole JM, Xiao H, Adams JW, Disher KM, Zhao H, Bernstein KE. PMID: 12620918.
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    143. Role of bradykinin in angiotensin-converting enzyme knockout mice. Am J Physiol Heart Circ Physiol. 2003 Jun; 284(6):H1969-77. Xiao HD, Fuchs S, Cole JM, Disher KM, Sutliff RL, Bernstein KE. PMID: 12637363.
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    144. Mice lacking endothelial ACE: normal blood pressure with elevated angiotensin II. Hypertension. 2003 Feb; 41(2):313-21. Cole JM, Khokhlova N, Sutliff RL, Adams JW, Disher KM, Zhao H, Capecchi MR, Corvol P, Bernstein KE. PMID: 12574101.
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    145. Impaired urine concentration and absence of tissue ACE: involvement of medullary transport proteins. Am J Physiol Renal Physiol. 2002 Sep; 283(3):F517-24. Klein JD, Le Quach D, Cole JM, Disher K, Mongiu AK, Wang X, Bernstein KE, Sands JM. PMID: 12167603.
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    146. Two ACEs and a heart. Nature. 2002 Jun 20; 417(6891):799-802. Bernstein KE. PMID: 12075331.
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    147. Mice lacking endothelial angiotensin-converting enzyme have a normal blood pressure. Circ Res. 2002 Jan 11; 90(1):87-92. Cole J, Quach DL, Sundaram K, Corvol P, Capecchi MR, Bernstein KE. PMID: 11786523.
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    148. Lack of angiotensin II-facilitated erythropoiesis causes anemia in angiotensin-converting enzyme-deficient mice. J Clin Invest. 2000 Dec; 106(11):1391-8. Cole J, Ertoy D, Lin H, Sutliff RL, Ezan E, Guyene TT, Capecchi M, Corvol P, Bernstein KE. PMID: 11104792; PMCID: PMC381466.
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    149. ACE knockout mice--lessons for adult nephrology. Nephrol Dial Transplant. 1998 Dec; 13(12):2991-4. Bernstein KE. PMID: 9870448.
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    150. The role of tissue angiotensin-converting enzyme (ACE): studies of ACE mutant mice. Am J Cardiol. 1998 Nov 19; 82(10A):5S-7S. Bernstein KE. PMID: 9860346.
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    151. Coil embolization of a trigeminal-cavernous fistula. AJNR Am J Neuroradiol. 1998 Nov-Dec; 19(10):1953-4. Bernstein K, Teitelbaum GP, Herman B, Giannotta SL. PMID: 9874555; PMCID: PMC8337731.
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    152. Endovascular coil occlusion of a traumatic basilar-cavernous fistula: technical report. Neurosurgery. 1998 Jun; 42(6):1394-7; discussion 1397-8. Teitelbaum GP, Bernstein K, Choi S, Giannotta SL. PMID: 9632204.
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    153. The functional role of angiotensin-converting enzyme as explored by using knockout mice. Adv Nephrol Necker Hosp. 1998; 28:213-23. Bernstein KE, Esther CR. PMID: 9889992.
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    154. Expression of testis angiotensin-converting enzyme is mediated by a cyclic AMP responsive element. Lab Invest. 1997 Nov; 77(5):483-8. Esther CR, Semeniuk D, Marino EM, Zhou Y, Overbeek PA, Bernstein KE. PMID: 9389791.
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    155. The role of Angiotensin-converting enzyme in blood pressure control, renal function, and male fertility. Trends Endocrinol Metab. 1997 Jul; 8(5):181-6. Esther CR, Marino EM, Bernstein KE. PMID: 18406804.
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    156. The critical role of tissue angiotensin-converting enzyme as revealed by gene targeting in mice. J Clin Invest. 1997 May 15; 99(10):2375-85. Esther CR, Marino EM, Howard TE, Machaud A, Corvol P, Capecchi MR, Bernstein KE. PMID: 9153279; PMCID: PMC508076.
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    157. Lessons from angiotensin-converting enzyme-deficient mice. Curr Opin Nephrol Hypertens. 1996 Nov; 5(6):463-7. Esther CR, Howard TE, Zhou Y, Capecchi MR, Marrero MB, Bernstein KE. PMID: 8978990.
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    158. cAMP-response element modulator tau is a positive regulator of testis angiotensin converting enzyme transcription. Proc Natl Acad Sci U S A. 1996 Oct 29; 93(22):12262-6. Zhou Y, Sun Z, Means AR, Sassone-Corsi P, Bernstein KE. PMID: 8901568; PMCID: PMC37978.
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    159. Tissue specific expression of testis angiotensin converting enzyme is not determined by the -32 nonconsensus TATA motif. Biochem Biophys Res Commun. 1996 Jun 05; 223(1):48-53. Zhou Y, Overbeek PA, Bernstein KE. PMID: 8660377.
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    160. Mice lacking angiotensin-converting enzyme have low blood pressure, renal pathology, and reduced male fertility. Lab Invest. 1996 May; 74(5):953-65. Esther CR, Howard TE, Marino EM, Goddard JM, Capecchi MR, Bernstein KE. PMID: 8642790.
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    161. Importance of tyrosine phosphorylation in angiotensin II type 1 receptor signaling. Hypertension. 1996 Mar; 27(3 Pt 2):476-80. Schieffer B, Paxton WG, Marrero MB, Bernstein KE. PMID: 8613189.
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    162. Angiotensin II-induced tyrosine phosphorylation in mesangial and vascular smooth muscle cells. Clin Exp Pharmacol Physiol. 1996 Jan; 23(1):83-8. Marrero MB, Schieffer B, Bernstein KE, Ling BN. PMID: 8713501.
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    163. Glucocorticoids induce angiotensin-converting enzyme expression in vascular smooth muscle. Hypertension. 1995 Mar; 25(3):343-9. Fishel RS, Eisenberg S, Shai SY, Redden RA, Bernstein KE, Berk BC. PMID: 7875759.
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    164. Identification of two positive transcriptional elements within the 91-base pair promoter for mouse testis angiotensin converting enzyme (testis ACE). Dev Genet. 1995; 16(2):201-9. Zhou Y, Delafontaine P, Martin BM, Bernstein KE. PMID: 7736668.
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    165. Fibroblast growth factor stimulates angiotensin converting enzyme expression in vascular smooth muscle cells. Possible mediator of the response to vascular injury. J Clin Invest. 1995 Jan; 95(1):377-87. Fishel RS, Thourani V, Eisenberg SJ, Shai SY, Corson MA, Nabel EG, Bernstein KE, Berk BC. PMID: 7814638; PMCID: PMC295441.
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    166. Chicken lacks the testis specific isozyme of angiotensin converting enzyme found in mammals. Biochem Biophys Res Commun. 1994 Dec 30; 205(3):1916-21. Esther CR, Thomas KE, Bernstein KE. PMID: 7811282.
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    167. Regulated expression of testis angiotensin-converting enzyme during spermatogenesis in mice. Biol Reprod. 1993 Jun; 48(6):1210-8. Langford KG, Zhou Y, Russell LD, Wilcox JN, Bernstein KE. PMID: 8391328.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    168. Structure and regulated expression of angiotensin-converting enzyme and the receptor for angiotensin II. Am J Kidney Dis. 1993 Apr; 21(4 Suppl 1):53-7. Bernstein KE, Shai SY, Howard T, Balogh R, Frenzel K, Langford K. PMID: 8385419.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    169. Sperm-specific expression of angiotensin-converting enzyme (ACE) is mediated by a 91-base-pair promoter containing a CRE-like element. Mol Cell Biol. 1993 Jan; 13(1):18-27. Howard T, Balogh R, Overbeek P, Bernstein KE. PMID: 8380220; PMCID: PMC358880.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    170. Bovine angiotensin converting enzyme cDNA cloning and regulation. Increased expression during endothelial cell growth arrest. Circ Res. 1992 Jun; 70(6):1274-81. Shai SY, Fishel RS, Martin BM, Berk BC, Bernstein KE. PMID: 1315639.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    171. Tissue specific expression of angiotensin converting enzyme. Agents Actions Suppl. 1992; 38 ( Pt 1):376-83. Bernstein KE, Howard TE, Shai SY, Langford KG, Balogh R. PMID: 1334622.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    172. Transgenic mice demonstrate a testis-specific promoter for angiotensin-converting enzyme. J Biol Chem. 1991 Aug 25; 266(24):15559-62. Langford KG, Shai SY, Howard TE, Kovac MJ, Overbeek PA, Bernstein KE. PMID: 1651914.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    173. Insulin-like growth factor I gene expression in vascular cells. Hypertension. 1991 May; 17(5):693-9. Delafontaine P, Bernstein KE, Alexander RW. PMID: 1708744.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    174. Transcription of testicular angiotensin-converting enzyme (ACE) is initiated within the 12th intron of the somatic ACE gene. Mol Cell Biol. 1990 Aug; 10(8):4294-302. Howard TE, Shai SY, Langford KG, Martin BM, Bernstein KE. PMID: 2164636; PMCID: PMC360974.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    175. Genomic DNA 5' to the mouse and human angiotensin-converting enzyme genes contains two distinct regions of conserved sequence. Biochem Biophys Res Commun. 1990 Mar 30; 167(3):1128-33. Shai SY, Langford KG, Martin BM, Bernstein KE. PMID: 2157425.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    176. A deeply recessed active site in angiotensin-converting enzyme is indicated from the binding characteristics of biotin-spacer-inhibitor reagents. Biochem Biophys Res Commun. 1990 Feb 28; 167(1):310-6. Bernstein KE, Welsh SL, Inman JK. PMID: 2155615.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    177. Mouse angiotensin-converting enzyme is a protein composed of two homologous domains. J Biol Chem. 1989 Jul 15; 264(20):11945-51. Bernstein KE, Martin BM, Edwards AS, Bernstein EA. PMID: 2545691.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    178. The isolation of angiotensin-converting enzyme cDNA. J Biol Chem. 1988 Aug 15; 263(23):11021-4. Bernstein KE, Martin BM, Bernstein EA, Linton J, Striker L, Striker G. PMID: 2841312.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    179. Partial protein sequence of mouse and bovine kidney angiotensin converting enzyme. Kidney Int. 1988 Mar; 33(3):652-5. Bernstein KE, Martin BM, Striker L, Striker G. PMID: 2835538.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    180. [Description of neurocutaneous melanoblastosis]. Psychiatr Neurol Med Psychol (Leipz). 1986 Oct; 38(10):597-605. Bernstein K, Möller P, Schneider J, Schreiber D, Tennstedt A, Winkler G. PMID: 3809302.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    181. [Metastases of the central nervous system: a prospective study. 3rd Communication: metastases in the pituitary gland, pineal gland, and choroid plexus (author's transl)]. Zentralbl Allg Pathol. 1982; 126(1-2):64-73. Schreiber D, Bernstein K, Schneider J. PMID: 7090603.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    182. [Metastases of the central nervous system: A prospective study. 2nd Communication: site and distribution patterns of brain metastases]. Zentralbl Allg Pathol. 1982; 126(1-2):53-63. Bernstein K, Schreiber D, Schneider J. PMID: 7090602.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
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