Takeshi Saito, MD, PhD
|Title||Assistant Professor of Medicine|
|School||Keck School of Medicine of USC|
Health Sciences Campus
Los Angeles California 90033
|Phone||+1 323 442 2260|
My research interest has been centered on hepatitis C virus (HCV) virology, pathogenesis, and virus-host interaction including immune response. For the past 10 years during my PhD and Post-Doctoral training, I have investigated viral-host interactions that regulate HCV viral replication through the activation of intracellular innate immune response. In recent years, I have focused on understanding how host cell innate immune pathways sense HCV infection and initiate the host response which involves type I interferon and proinflammatory cytokine production to regulate hepatic immunity. After recent transition to an independent junior faculty position at the University of Southern California (USC), Keck School of Medicine, my laboratory continues to investigate virus-host interactions that regulates disease outcome and pathogenesis of HCV infection. I have extensive expertise and skills in virology, cell signaling, cytokine biology, and cell biology.
My role as a physician specializing in the care of viral hepatitis at an academic medical center offers the unique integration of basic science and clinical/translational science into the laboratory research program, allowing us to set our aim as "research for the better healthcare". My chief goal is to become an established physician scientist with the skills and knowledge necessary to pursue a lasting career dedicated to translating discoveries in molecular virology into clinical practice or development of novel therapies. USC is supported by two major centers for the study of liver diseases: 1) USC Research Center for Liver Diseases, and 2) Southern California Research Center for ALPD and Cirrhosis. These center directors serve as consultants for the research program and career development. In summary, I have substantial expertise and a track record in the field of innate immunology against viral infection and am efficiently establishing an independent research program in an environment well suited for the study of liver diseases.
|ISICR||2008||International Society for Interferon & Cytokine Research Milstein Young Investigator Award|
|Viral Hepatitis Research Foundation of Japan ||2009||Viral Hepatitis Research Foundation of Japan Research Fellowship|
|AASLD and American Liver Foundation||2010
||2012||Liver Scholar Award |
|Japan Society of Hepatology||2010||2010 Hepatology Research High Citation Award|
|Baxter Foundation ||2011||Donald E. and Delia B. Baxter Foundation Faculty Fellow Award|
|International Meeting on Hepatitis C Virus & Related Viruses||2011||Travel Scholarship for 18th International Meeting on Hepatitis C Virus & Related Viruses|
|ISHSR||2013||Young Investigator Award International Symposium on Cells of the Hepatic Sinusoid |
|American Federation For Medical Research||2016||Western Region American Federation For Medical Research (WAFMR) Outstanding Investigator Award|
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