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Combination Therapy With Asciminib and Ponatinib as a Bridge to Brexucabtagene Autoleucel and Maintenance in a Patient With Relapsed Refractory Philadelphia Positive B-Cell Acute Lymphoblastic Leukemia. J Med Cases. 2024 Oct; 15(10):261-266.
Amin Muhammad A, Mir Ghazi E, Ali A, Tam E, Woan K, Chaudhary P, Yaghmour G, Ladha A. PMID: 39328803; PMCID: PMC11424108.
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Philadelphia-like B-cell acute lymphoblastic Leukaemia: Disease features and outcomes in the era of immunotherapy. Br J Haematol. 2024 Sep 18.
Ashouri K, Hom B, Ginosyan AA, Rahimi Y, Resnick K, Nittur V, Hwang J, Ireland R, Ann B, Adnani B, Bragasin EI, Chaudhary P, Ali A, Woan K, Tam EL, Siddiqi I, Ladha A, Yaghmour G. PMID: 39295195.
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PubMed Mentions: Fields:
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Graft Versus Host Disease Prophylaxis in Matched Donor Stem Cell Transplantation: Post-transplantation Cyclophosphamide Combinations Versus Methotrexate/Tacrolimus. Transplant Proc. 2024 Sep; 56(7):1671-1677.
Ashouri K, Fernandez E, Ginosyan A, Feliciano CM, Hom B, Rodman J, Ali A, Ladha A, Woan K, Tam E, Chaudhary P, Yaghmour G. PMID: 39174390.
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PubMed Mentions: Fields:
Translation:
Humans
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Donor matters: Donor selection impact on hematopoietic stem cell transplantation outcomes in Hispanic patients with B-cell acute lymphocytic leukemia: Insights from a myeloablative HSCT study. Leuk Res. 2024 Jun; 141:107501.
Ashouri K, Ginosyan AA, Chu M, Hom B, Hwang J, Resnick K, Rahimi Y, Chaudhary P, Woan K, Siddiqi I, Ladha A, Ali A, Tam EL, Yaghmour G. PMID: 38631149.
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PubMed Mentions: Fields:
Translation:
Humans
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Post-stem cell transplant maintenance in FLT3mut acute myeloid leukemia - A retrospective analysis: Outcomes are improved with midostaurin but not with gilteritinib. EJHaem. 2024 Apr; 5(2):423-427.
Ashouri K, Chennapan K, Martynova A, Nazaretyan S, Ali A, Ginosyan AA, Tam E, Ladha A, Woan K, Chaudhary P, Siddiqi I, Yaghmour G. PMID: 38633126; PMCID: PMC11020142.
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PubMed Mentions:
1
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Case report: Pulse cyclophosphamide for treatment of multi-agent-refractory hepatic graft-versus-host disease. Front Oncol. 2024; 14:1329893.
Cai Y, Ali A, Filler E, Bayati R, Toma T, Zaki O, Yaghmour G, Ladha A, Woan K, Tam E, Chaudhary PM. PMID: 38410106; PMCID: PMC10894980.
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PubMed Mentions:
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Concordance of Next-Generation Sequencing and Multiparametric Flow Cytometry Methods for Detecting Measurable Residual Disease in Adult Acute Lymphoblastic Leukemia: Optimizing Prediction of Clinical Outcomes From a Single-Center Study. Clin Lymphoma Myeloma Leuk. 2024 03; 24(3):e59-e66.e2.
Ashouri K, Nittur V, Ginosyan AA, Hwang J, Adnani B, Chen D, Savitala-Damerla L, Schiff K, Chaudhary P, Kovach AE, Ladha A, Siddiqi I, Ali A, Woan K, Tam E, Yaghmour G. PMID: 38061959.
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PubMed Mentions: Fields:
Translation:
Humans
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Unique challenges to diagnosing sweet syndrome following induction chemotherapy for relapsed Acute Myeloid Leukemia (AML): A case and brief-review. Respir Med Case Rep. 2023; 46:101922.
Nazaretyan S, Ali A, Yaghmour G, Tong A, Castillo V, Rodrigues S, Ladha A, Woan K, Tam E, Shi SY, Bateshansky D, Chaudhary PM. PMID: 37841284; PMCID: PMC10570145.
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PubMed Mentions:
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Expert consensus on microtransplant for acute myeloid leukemia in elderly patients -report from the international microtransplant interest group. Heliyon. 2023 Apr; 9(4):e14924.
Ai H, Chao NJ, Rizzieri DA, Huang X, Spitzer TR, Wang J, Guo M, Keating A, Krakow EF, Blaise D, Ma J, Wu D, Reagan J, Gergis U, Duarte RF, Chaudhary PM, Hu K, Yu C, Sun Q, Fuchs E, Cai B, Huang Y, Qiao J, Gottlieb D, Schultz KR, Liu M, Chen X, Chen W, Wang J, Zhang X, Li J, Huang H, Sun Z, Li F, Yang L, Zhang L, Li L, Liu K, Jin J, Liu Q, Liu D, Gao C, Fan C, Wei L, Zhang X, Hu L, Zhang W, Tian Y, Han W, Zhu J, Xiao Z, Zhou D, Zhang B, Jia Y, Zhang Y, Wu X, Shen X, Lu X, Zhan X, Sun X, Xiao Y, Wang J, Shi X, Zheng B, Chen J, Ding B, Wang Z, Zhou F, Zhang M, Zhang Y, Sun J, Xia B, Chen B, Ma L. PMID: 37089296; PMCID: PMC10119710.
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PubMed Mentions:
1
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Real world experience: Examining outcomes using letermovir for CMV prophylaxis in high-risk allogeneic hematopoietic stem cell patients in the setting of using T-cell depletion as GVHD prophylaxis. Transpl Immunol. 2023 02; 76:101769.
Dwabe S, Hsiao M, Ali A, Rodman J, Savitala-Damerla L, Nazaretyan S, Kimberly Schiff NP, Tam E, Ladha A, Woan K, Chaudhary P, Yaghmour G. PMID: 36464218.
View in:
PubMed Mentions: Fields:
Translation:
HumansCells
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Unique Challenges to Diagnosing Human Herpesvirus-6 (HHV-6) Encephalitis Following Post-Hematopoietic Stem Cell Transplant: A Case and Brief Review. Cell Transplant. 2022 Jan-Dec; 31:9636897221119734.
Zhu H, Ali A, Woan KV, Tam E, Yaghmour G, Flores A, Chaudhary P. PMID: 36927092; PMCID: PMC9478732.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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A novel thermostable beetle luciferase based cytotoxicity assay. Sci Rep. 2021 05 11; 11(1):10002.
Choi S, Matta H, Gopalakrishnan R, Natarajan V, Gong S, Jeronimo A, Kuo WY, Bravo B, Chaudhary PM. PMID: 33976304; PMCID: PMC8113442.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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The time to offer treatments for COVID-19. Expert Opin Investig Drugs. 2021 May; 30(5):505-518.
Ngo BT, Marik P, Kory P, Shapiro L, Thomadsen R, Iglesias J, Ditmore S, Rendell M, Varon J, Dubé M, Nanda N, In G, Arkfeld D, Chaudhary P, Campese VM, Hanna DL, Sawcer DE, Ehresmann G, Peng D, Smogorewski M, Armstrong A, Dasgupta R, Sattler F, Brennan-Rieder D, Mussini C, Mitja O, Soriano V, Peschanski N, Hayem G, Confalonieri M, Piccirillo MC, Lobo-Ferreira A, Bello Rivero I, Turkia M, Vinjevoll EH, Griffin D, Hung IF. PMID: 33721548; PMCID: PMC8074648.
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PubMed Mentions:
19 Fields:
Translation:
Humans
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Narciclasine, an isocarbostyril alkaloid, has preferential activity against primary effusion lymphoma. Sci Rep. 2020 03 31; 10(1):5712.
Gopalakrishnan R, Matta H, Choi S, Chaudhary PM. PMID: 32235878; PMCID: PMC7109099.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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A Fast and Sensitive Luciferase-based Assay for Antibody Engineering and Design of Chimeric Antigen Receptors. Sci Rep. 2020 02 11; 10(1):2318.
Natarajan V, Gopalakrishnan R, Matta H, Choi S, Gong S, Jeronimo A, Keerthipati PS, Morales A, Venkatesh H, Chaudhary PM. PMID: 32047180; PMCID: PMC7012821.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
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A novel luciferase-based assay for the detection of Chimeric Antigen Receptors. Sci Rep. 2019 02 13; 9(1):1957.
Gopalakrishnan R, Matta H, Choi S, Natarajan V, Prins R, Gong S, Zenunovic A, Narasappa N, Patel F, Prakash R, Chaudhary V, Sikri V, Chitnis SD, Kochegarov A, Wang D, Falat M, Kahn M, Keerthipati PS, Sharma N, Lenka J, Stieben TM, Braun J, Batra A, Purvis K, Ito K, Lee JH, Jeronimo A, Zamora HM, Membreno A, Qiu Q, Peshin S, Namburu L, Chaudhary PM. PMID: 30760795; PMCID: PMC6374361.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Unrelated HLA mismatched microtransplantation in a patient with refractory secondary acute myeloid leukemia. Leuk Res Rep. 2018; 9:18-20.
Punwani N, Merin N, Mohrbacher A, Yaghmour G, Sano A, Ramezani L, Chaudhary PM, Ramsingh G. PMID: 29556468; PMCID: PMC5856665.
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PubMed Mentions:
3
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Development and characterization of a novel luciferase based cytotoxicity assay. Sci Rep. 2018 01 09; 8(1):199.
Matta H, Gopalakrishnan R, Choi S, Prakash R, Natarajan V, Prins R, Gong S, Chitnis SD, Kahn M, Han X, Chaudhary V, Soni A, Sernas J, Khan P, Wang D, Chaudhary PM. PMID: 29317736; PMCID: PMC5760659.
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PubMed Mentions:
28 Fields:
Translation:
HumansCells
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Immunomodulatory drugs target IKZF1-IRF4-MYC axis in primary effusion lymphoma in a cereblon-dependent manner and display synergistic cytotoxicity with BRD4 inhibitors. Oncogene. 2016 Apr 07; 35(14):1797-810.
Gopalakrishnan R, Matta H, Tolani B, Triche T, Chaudhary PM. PMID: 26119939; PMCID: PMC4486341.
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PubMed Mentions:
73 Fields:
Translation:
HumansAnimalsCells
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Toxicity profile of repeated doses of PEG-asparaginase incorporated into a pediatric-type regimen for adult acute lymphoblastic leukemia. Eur J Haematol. 2016 Apr; 96(4):375-80.
Aldoss I, Douer D, Behrendt CE, Chaudhary P, Mohrbacher A, Vrona J, Pullarkat V. PMID: 26095294; PMCID: PMC9496150.
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PubMed Mentions:
26 Fields:
Translation:
Humans
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DiseaseConnect: a comprehensive web server for mechanism-based disease-disease connections. Nucleic Acids Res. 2014 Jul; 42(Web Server issue):W137-46.
Liu CC, Tseng YT, Li W, Wu CY, Mayzus I, Rzhetsky A, Sun F, Waterman M, Chen JJ, Chaudhary PM, Loscalzo J, Crandall E, Zhou XJ. PMID: 24895436; PMCID: PMC4086092.
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PubMed Mentions:
55 Fields:
Translation:
Humans
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NEMO is essential for Kaposi's sarcoma-associated herpesvirus-encoded vFLIP K13-induced gene expression and protection against death receptor-induced cell death, and its N-terminal 251 residues are sufficient for this process. J Virol. 2014 Jun; 88(11):6345-54.
Tolani B, Matta H, Gopalakrishnan R, Punj V, Chaudhary PM. PMID: 24672029; PMCID: PMC4093867.
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PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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A purine scaffold HSP90 inhibitor BIIB021 has selective activity against KSHV-associated primary effusion lymphoma and blocks vFLIP K13-induced NF-κB. Clin Cancer Res. 2013 Sep 15; 19(18):5016-26.
Gopalakrishnan R, Matta H, Chaudhary PM. PMID: 23881928; PMCID: PMC3804723.
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PubMed Mentions:
30 Fields:
Translation:
HumansAnimalsCells
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Targeting Myc in KSHV-associated primary effusion lymphoma with BET bromodomain inhibitors. Oncogene. 2014 May 29; 33(22):2928-37.
Tolani B, Gopalakrishnan R, Punj V, Matta H, Chaudhary PM. PMID: 23792448; PMCID: PMC4892892.
View in:
PubMed Mentions:
62 Fields:
Translation:
HumansAnimalsCells
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Major non-ABO incompatibility caused by anti-Jk(a) in a patient before allogeneic hematopoietic stem cell transplantation. Immunohematology. 2013; 29(1):11-4.
Kim MY, Chaudhary P, Shulman IA, Pullarkat V. PMID: 24046917.
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PubMed Mentions:
1 Fields:
Translation:
Humans
-
Kaposi's sarcoma-associated herpesvirus oncoprotein K13 protects against B cell receptor-induced growth arrest and apoptosis through NF-κB activation. J Virol. 2013 Feb; 87(4):2242-52.
Graham C, Matta H, Yang Y, Yi H, Suo Y, Tolani B, Chaudhary PM. PMID: 23236068; PMCID: PMC3571451.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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A computational profiling of changes in gene expression and transcription factors induced by vFLIP K13 in primary effusion lymphoma. PLoS One. 2012; 7(5):e37498.
Punj V, Matta H, Chaudhary PM. PMID: 22624040; PMCID: PMC3356309.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Kaposi's sarcoma associated herpesvirus encoded viral FLICE inhibitory protein K13 activates NF-κB pathway independent of TRAF6, TAK1 and LUBAC. PLoS One. 2012; 7(5):e36601.
Matta H, Gopalakrishnan R, Graham C, Tolani B, Khanna A, Yi H, Suo Y, Chaudhary PM. PMID: 22590573; PMCID: PMC3348130.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
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Constitutive NF-kappaB activation confers interleukin 6 (IL6) independence and resistance to dexamethasone and Janus kinase inhibitor INCB018424 in murine plasmacytoma cells. J Biol Chem. 2011 Aug 12; 286(32):27988-97.
Yang Y, Groshong JS, Matta H, Gopalakrishnan R, Yi H, Chaudhary PM. PMID: 21705340; PMCID: PMC3151044.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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A20 is induced by Kaposi sarcoma-associated herpesvirus-encoded viral FLICE inhibitory protein (vFLIP) K13 and blocks K13-induced nuclear factor-kappaB in a negative feedback manner. J Biol Chem. 2011 Jun 17; 286(24):21555-64.
Matta H, Gopalakrishnan R, Punj V, Yi H, Suo Y, Chaudhary PM. PMID: 21531730; PMCID: PMC3122214.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Kaposi sarcoma-associated herpesvirus-encoded viral FLICE inhibitory protein (vFLIP) K13 cooperates with Myc to promote lymphoma in mice. Cancer Biol Ther. 2010 Nov 15; 10(10):1033-40.
Ahmad A, Groshong JS, Matta H, Schamus S, Punj V, Robinson LJ, Gill PS, Chaudhary PM. PMID: 20818173; PMCID: PMC3047095.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Immune evasion by Kaposi's sarcoma-associated herpesvirus. Future Microbiol. 2010 Sep; 5(9):1349-65.
Lee HR, Lee S, Chaudhary PM, Gill P, Jung JU. PMID: 20860481; PMCID: PMC3076960.
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PubMed Mentions:
43 Fields:
Translation:
HumansAnimalsCells
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Lack of evidence for direct involvement of Merkel cell polyomavirus (MCV) in chronic lymphocytic leukemia (CLL). Blood. 2010 Jun 10; 115(23):4973-4.
Tolstov YL, Arora R, Scudiere SC, Busam K, Chaudhary PM, Chang Y, Moore PS. PMID: 20538816; PMCID: PMC2890166.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Induction, regulation, and biologic function of Axl receptor tyrosine kinase in Kaposi sarcoma. Blood. 2010 Jul 15; 116(2):297-305.
Liu R, Gong M, Li X, Zhou Y, Gao W, Tulpule A, Chaudhary PM, Jung J, Gill PS. PMID: 20442363; PMCID: PMC2910613.
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PubMed Mentions:
43 Fields:
Translation:
HumansAnimalsCells
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X-linked ectodermal dysplasia receptor is downregulated in breast cancer via promoter methylation. Clin Cancer Res. 2010 Feb 15; 16(4):1140-8.
Punj V, Matta H, Chaudhary PM. PMID: 20145163; PMCID: PMC2822888.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Kaposi's sarcoma-associated herpesvirus-encoded viral FLICE inhibitory protein (vFLIP) K13 suppresses CXCR4 expression by upregulating miR-146a. Oncogene. 2010 Mar 25; 29(12):1835-44.
Punj V, Matta H, Schamus S, Tamewitz A, Anyang B, Chaudhary PM. PMID: 20023696; PMCID: PMC2845732.
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PubMed Mentions:
34 Fields:
Translation:
HumansCells
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KSHV-induced notch components render endothelial and mural cell characteristics and cell survival. Blood. 2010 Jan 28; 115(4):887-95.
Liu R, Li X, Tulpule A, Zhou Y, Scehnet JS, Zhang S, Lee JS, Chaudhary PM, Jung J, Gill PS. PMID: 19965636; PMCID: PMC2815507.
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PubMed Mentions:
41 Fields:
Translation:
HumansAnimalsCells
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Human Merkel cell polyomavirus infection I. MCV T antigen expression in Merkel cell carcinoma, lymphoid tissues and lymphoid tumors. Int J Cancer. 2009 Sep 15; 125(6):1243-9.
Shuda M, Arora R, Kwun HJ, Feng H, Sarid R, Fernández-Figueras MT, Tolstov Y, Gjoerup O, Mansukhani MM, Swerdlow SH, Chaudhary PM, Kirkwood JM, Nalesnik MA, Kant JA, Weiss LM, Moore PS, Chang Y. PMID: 19499546; PMCID: PMC6388400.
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PubMed Mentions:
153 Fields:
Translation:
HumansCells
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Integrated microarray and multiplex cytokine analyses of Kaposi's Sarcoma Associated Herpesvirus viral FLICE Inhibitory Protein K13 affected genes and cytokines in human blood vascular endothelial cells. BMC Med Genomics. 2009 Aug 06; 2:50.
Punj V, Matta H, Schamus S, Chaudhary PM. PMID: 19660139; PMCID: PMC2732924.
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PubMed Mentions:
18 Fields:
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Induction of CCL20 production by Kaposi sarcoma-associated herpesvirus: role of viral FLICE inhibitory protein K13-induced NF-kappaB activation. Blood. 2009 May 28; 113(22):5660-8.
Punj V, Matta H, Schamus S, Yang T, Chang Y, Chaudhary PM. PMID: 19324905; PMCID: PMC2689059.
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PubMed Mentions:
15 Fields:
Translation:
HumansCells
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Resolving "kinks" of chemotherapy in melanoma. J Natl Cancer Inst. 2008 Jun 18; 100(12):833-5.
Moschos SJ, Chaudhary PM, Kirkwood JM. PMID: 18544737.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
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A nuclear role for Kaposi's sarcoma-associated herpesvirus-encoded K13 protein in gene regulation. Oncogene. 2008 Sep 04; 27(39):5243-53.
Matta H, Punj V, Schamus S, Mazzacurati L, Chen AM, Song R, Yang T, Chaudhary PM. PMID: 18469854.
View in:
PubMed Mentions:
12 Fields:
Translation:
Cells
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Proteasome inhibitor Bortezomib induces cell cycle arrest and apoptosis in cell lines derived from Ewing's sarcoma family of tumors and synergizes with TRAIL. Cancer Biol Ther. 2008 Apr; 7(4):603-8.
Lu G, Punj V, Chaudhary PM. PMID: 18223318.
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PubMed Mentions:
23 Fields:
Translation:
HumansCells
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Adenoviral-mediated gene transfer of ectodysplasin-A2 results in induction of apoptosis and cell-cycle arrest in osteosarcoma cell lines. Cancer Gene Ther. 2007 Nov; 14(11):927-33.
Chang B, Punj V, Shindo M, Chaudhary PM. PMID: 17693991.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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In primary effusion lymphoma cells, MYB transcriptional repression is associated with v-FLIP expression during latent KSHV infection while both v-FLIP and v-GPCR become involved during the lytic cycle. Br J Haematol. 2007 Aug; 138(4):487-501.
Lacoste V, Nicot C, Gessain A, Valensi F, Gabarre J, Matta H, Chaudhary PM, Mahieux R. PMID: 17659053.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Kaposi's sarcoma-associated herpesvirus (KSHV) oncoprotein K13 bypasses TRAFs and directly interacts with the IkappaB kinase complex to selectively activate NF-kappaB without JNK activation. J Biol Chem. 2007 Aug 24; 282(34):24858-65.
Matta H, Mazzacurati L, Schamus S, Yang T, Sun Q, Chaudhary PM. PMID: 17597077.
View in:
PubMed Mentions:
36 Fields:
Translation:
HumansCells
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Induction of spindle cell morphology in human vascular endothelial cells by human herpesvirus 8-encoded viral FLICE inhibitory protein K13. Oncogene. 2007 Mar 08; 26(11):1656-60.
Matta H, Surabhi RM, Zhao J, Punj V, Sun Q, Schamus S, Mazzacurati L, Chaudhary PM. PMID: 16936773.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansCells
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Induction of IL-8 expression by human herpesvirus 8 encoded vFLIP K13 via NF-kappaB activation. Oncogene. 2006 May 04; 25(19):2717-26.
Sun Q, Matta H, Lu G, Chaudhary PM. PMID: 16418726.
View in:
PubMed Mentions:
55 Fields:
Translation:
HumansCells
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Constitutive NF-kappaB activation, normal Fas-induced apoptosis, and increased incidence of lymphoma in human herpes virus 8 K13 transgenic mice. Proc Natl Acad Sci U S A. 2005 Sep 06; 102(36):12885-90.
Chugh P, Matta H, Schamus S, Zachariah S, Kumar A, Richardson JA, Smith AL, Chaudhary PM. PMID: 16120683; PMCID: PMC1200255.
View in:
PubMed Mentions:
63 Fields:
Translation:
AnimalsCells
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Kaposi's sarcoma associated herpes virus-encoded viral FLICE inhibitory protein activates transcription from HIV-1 Long Terminal Repeat via the classical NF-kappaB pathway and functionally cooperates with Tat. Retrovirology. 2005 Feb 15; 2:9.
Sun Q, Matta H, Chaudhary PM. PMID: 15713234; PMCID: PMC554086.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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The proteasome inhibitor bortezomib (PS-341) inhibits growth and induces apoptosis in primary effusion lymphoma cells. Cancer Biol Ther. 2005 Jan; 4(1):77-82.
Matta H, Chaudhary PM. PMID: 15662128.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansCells
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An evolutionary conserved pathway of nuclear factor-kappaB activation involving caspase-mediated cleavage and N-end rule pathway-mediated degradation of IkappaBalpha. J Biol Chem. 2004 Sep 17; 279(38):39358-65.
Rathore N, Matta H, Chaudhary PM. PMID: 15252032.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Activation of alternative NF-kappa B pathway by human herpes virus 8-encoded Fas-associated death domain-like IL-1 beta-converting enzyme inhibitory protein (vFLIP). Proc Natl Acad Sci U S A. 2004 Jun 22; 101(25):9399-404.
Matta H, Chaudhary PM. PMID: 15190178; PMCID: PMC438988.
View in:
PubMed Mentions:
97 Fields:
Translation:
HumansCells
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Aberrant methylation of trail decoy receptor genes is frequent in multiple tumor types. Int J Cancer. 2004 May 01; 109(5):786-92.
Shivapurkar N, Toyooka S, Toyooka KO, Reddy J, Miyajima K, Suzuki M, Shigematsu H, Takahashi T, Parikh G, Pass HI, Chaudhary PM, Gazdar AF. PMID: 14999791.
View in:
PubMed Mentions:
51 Fields:
Translation:
HumansAnimalsCells
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The ectodermal dysplasia receptor represses the Lef-1/beta-catenin-dependent transcription independent of NF-kappaB activation. Biochem Biophys Res Commun. 2004 Feb 27; 315(1):73-8.
Shindo M, Chaudhary PM. PMID: 15013427.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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The human herpes virus 8-encoded viral FLICE-inhibitory protein induces cellular transformation via NF-kappaB activation. J Biol Chem. 2003 Dec 26; 278(52):52437-45.
Sun Q, Zachariah S, Chaudhary PM. PMID: 14563855.
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PubMed Mentions:
60 Fields:
Translation:
HumansAnimalsCells
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Molecular genetic analysis of human herpes virus 8-encoded viral FLICE inhibitory protein-induced NF-kappaB activation. J Biol Chem. 2003 Dec 26; 278(52):52406-11.
Matta H, Sun Q, Moses G, Chaudhary PM. PMID: 14561765.
View in:
PubMed Mentions:
31 Fields:
Translation:
HumansAnimalsCells
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Use of adeno-associated viral vector for delivery of small interfering RNA. Oncogene. 2003 Aug 28; 22(36):5712-5.
Tomar RS, Matta H, Chaudhary PM. PMID: 12944921.
View in:
PubMed Mentions:
50 Fields:
Translation:
Cells
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Eiger and its receptor, Wengen, comprise a TNF-like system in Drosophila. Oncogene. 2003 Jul 31; 22(31):4860-7.
Kauppila S, Maaty WS, Chen P, Tomar RS, Eby MT, Chapo J, Chew S, Rathore N, Zachariah S, Sinha SK, Abrams JM, Chaudhary PM. PMID: 12894227.
View in:
PubMed Mentions:
65 Fields:
Translation:
AnimalsCells
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Use of lentiviral vectors for delivery of small interfering RNA. Cancer Biol Ther. 2003 Mar-Apr; 2(2):206-10.
Matta H, Hozayev B, Tomar R, Chugh P, Chaudhary PM. PMID: 12750565.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Loss of expression of death-inducing signaling complex (DISC) components in lung cancer cell lines and the influence of MYC amplification. Oncogene. 2002 Dec 05; 21(55):8510-4.
Shivapurkar N, Reddy J, Matta H, Sathyanarayana UG, Huang CX, Toyooka S, Minna JD, Chaudhary PM, Gazdar AF. PMID: 12466971.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansCells
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Role of MRIT/cFLIP in protection against chemotherapy-induced apoptosis. Cancer Biol Ther. 2002 Nov-Dec; 1(6):652-60.
Matta H, Eby MT, Gazdar AF, Chaudhary PM. PMID: 12642689.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCells
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The human herpes virus 8-encoded viral FLICE inhibitory protein protects against growth factor withdrawal-induced apoptosis via NF-kappa B activation. Blood. 2003 Mar 01; 101(5):1956-61.
Sun Q, Matta H, Chaudhary PM. PMID: 12406869.
View in:
PubMed Mentions:
46 Fields:
Translation:
HumansCells
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Deregulation of caspase 8 and 10 expression in pediatric tumors and cell lines. Cancer Res. 2002 Oct 15; 62(20):5897-901.
Harada K, Toyooka S, Shivapurkar N, Maitra A, Reddy JL, Matta H, Miyajima K, Timmons CF, Tomlinson GE, Mastrangelo D, Hay RJ, Chaudhary PM, Gazdar AF. PMID: 12384554.
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64 Fields:
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HumansCells
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Role of TRAF3 and -6 in the activation of the NF-kappa B and JNK pathways by X-linked ectodermal dysplasia receptor. J Biol Chem. 2002 Nov 22; 277(47):44953-61.
Sinha SK, Zachariah S, Quiñones HI, Shindo M, Chaudhary PM. PMID: 12270937.
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28 Fields:
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HumansAnimalsCells
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The human herpes virus 8-encoded viral FLICE inhibitory protein physically associates with and persistently activates the Ikappa B kinase complex. J Biol Chem. 2002 Apr 19; 277(16):13745-51.
Liu L, Eby MT, Rathore N, Sinha SK, Kumar A, Chaudhary PM. PMID: 11830587.
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114 Fields:
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HumansCells
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Cytotoxicity of Tumor necrosis factor related apoptosis-inducing ligand towards Ewing's sarcoma cell lines. Oncogene. 2001 Feb 22; 20(8):1010-4.
Kumar A, Jasmin A, Eby MT, Chaudhary PM. PMID: 11314037.
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PubMed Mentions:
7 Fields:
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Cells
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Activation of the NF-kappaB pathway by caspase 8 and its homologs. Oncogene. 2000 Sep 14; 19(39):4451-60.
Chaudhary PM, Eby MT, Jasmin A, Kumar A, Liu L, Hood L. PMID: 11002417.
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93 Fields:
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HumansCells
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TAJ, a novel member of the tumor necrosis factor receptor family, activates the c-Jun N-terminal kinase pathway and mediates caspase-independent cell death. J Biol Chem. 2000 May 19; 275(20):15336-42.
Eby MT, Jasmin A, Kumar A, Sharma K, Chaudhary PM. PMID: 10809768.
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31 Fields:
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HumansAnimalsCells
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Modulation of the NF-kappa B pathway by virally encoded death effector domains-containing proteins. Oncogene. 1999 Oct 14; 18(42):5738-46.
Chaudhary PM, Jasmin A, Eby MT, Hood L. PMID: 10523854.
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140 Fields:
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HumansAnimalsCells
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Cloning and characterization of two Toll/Interleukin-1 receptor-like genes TIL3 and TIL4: evidence for a multi-gene receptor family in humans. Blood. 1998 Jun 01; 91(11):4020-7.
Chaudhary PM, Ferguson C, Nguyen V, Nguyen O, Massa HF, Eby M, Jasmin A, Trask BJ, Hood L, Nelson PS. PMID: 9596645.
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PubMed Mentions:
42 Fields:
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HumansAnimalsCells
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Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway. Immunity. 1997 Dec; 7(6):821-30.
Chaudhary PM, Eby M, Jasmin A, Bookwalter A, Murray J, Hood L. PMID: 9430227.
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190 Fields:
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HumansAnimalsCells
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MRIT, a novel death-effector domain-containing protein, interacts with caspases and BclXL and initiates cell death. Proc Natl Acad Sci U S A. 1997 Oct 14; 94(21):11333-8.
Han DK, Chaudhary PM, Wright ME, Friedman C, Trask BJ, Riedel RT, Baskin DG, Schwartz SM, Hood L. PMID: 9326610; PMCID: PMC23459.
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PubMed Mentions:
48 Fields:
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HumansAnimalsCells
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Expression and activity of the multidrug resistance P-glycoprotein in human peripheral blood lymphocytes. Blood. 1992 Dec 01; 80(11):2735-9.
Chaudhary PM, Mechetner EB, Roninson IB. PMID: 1360267.
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78 Fields:
Translation:
HumansCells