Preet M Chaudhary, MD, PhD

Title(s)Professor of Medicine
SchoolKeck School of Medicine of Usc
Address1441 Eastlake Ave.
Health Sciences Campus
Los Angeles CA 90033
Phone+1 323 865 3950
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    Other Positions
    Title(s)Bloom Family Chair in Lymphoma Research

    Title(s)Chief, Nohl Division of Hematology and Center for Blood Diseases in the Department of Medicine

    Title(s)Director for Bone Marrow Transplant


    Collapse Biography 
    Collapse Awards and Honors
    Leukemia Lymphoma Society2005  - 2008Translational Research Award
    Leukemia Lymphoma Society2008  - 2011Translational Research Award
    Multiple Myeloma Research Foundation2005  - 2006Senior Research Award
    2004American Society for Clinical Investigations
    Leukemia Research Foundation1999  - 2000New Investigator Award
    Howard Hughes Institutes1998  - 2001New Faculty Start-Up Award
    Damon Runyon-Walter Winchell Foundation1995  - 1998Postdoctoral Fellowship
    March of Dimes Birth Defects Foundation1990  - 1992Pre-doctoral Fellowship
    1986Second Prize in Ophthalmology
    1986Gold Medal in Surgery
    1985Second Prize in Pathology
    1984  - 1985Distinctions in Anatomy, Physiology Biochemistry and Pharmacology
    1984Honors in First Professional M.B.B.S
    1981Pre-Medical University Merit Certificate (First Rank in the College)
    1981  - 1986National Talent Search Scholarship

    Collapse Overview 
    Collapse Overview
    Preet M. Chaudhary, M.D., Ph.D. is chief of the Jane Anne Nohl Division of Hematology and Center for the study of Blood Diseases in the Department of Medicine, and coleader of the Molecular Genetics Program at the USC Norris Comprehensive Cancer Center. He is also Professor of Medicine, Ronald H. Bloom Family Chair in Lymphoma Research, and Program Director of the USC/Norris Blood and Marrow Transplant Program.

    As a physician-scientist dedicated to hematologic oncology, Dr. Chaudhary has research interests in several areas of cancer, including AIDS-associated cancers, cancer drug resistance, biology of normal and leukemic hematopoietic stem cells, programmed cell death and cellular signaling. He is also interested in molecularly targeted and cellular therapies for leukemias, lymphomas, multiple myeloma and solid tumors. Current work in Dr. Chaudhary's laboratory is focused on developing novel strategies to improve the outcome of stem cell transplantation and the use of chimeric antigen receptor modified T cells for the treatment of cancer.

    Dr. Chaudhary holds six U.S. patents and has published in some of the top scientific journals, including Cell, Immunity, JNCI, PNAS and Blood. He has served as a peer-reviewer for several national and international cancer research funding agencies and has been elected to the prestigious American Society for Clinical Investigations, an honor society of the top physician-scientists in the country.

    Collapse Research 
    Collapse Research Activities and Funding
    Role of IKK epsilon in KSHV/HHV8 associated malignancies
    NIH R01DE025804Mar 4, 2016 - Feb 28, 2021
    Role: Principal Investigator
    A High Throughput Protein Complementation Assay for Inhibitors of NEMO-K13 Intera
    NIH R01CA139119Jul 1, 2010 - Jun 30, 2014
    Role: Principal Investigator
    Cell Penetrating Helical Peptide Inhibitors of vFLIP K13
    NIH R01DE019811Jun 1, 2010 - Mar 31, 2016
    Role: Principal Investigator
    Small Molecule Inhibitors of K13-Induced NF-kB Activation
    NIH R21NS063905Jun 15, 2008 - May 31, 2010
    Role: Principal Investigator
    Role of vFLIP K13 in Bone Marrow Failure Syndrome Associated with Infection by Hu
    NIH R21HL085189May 10, 2007 - Oct 30, 2009
    Role: Principal Investigator
    Role of Arsenic Trioxide in Primary Effusion Lymphoma
    NIH R01CA124621Dec 1, 2006 - Nov 30, 2012
    Role: Principal Investigator
    Genes in X-linked Ectodermal Dysplasia Receptor
    NIH R01DE015189Apr 1, 2003 - Mar 31, 2008
    Role: Principal Investigator
    Role of orf-K13, an HHV8 Encoded vFLIP, in the Pathogenesis of AIDS-related Malig
    NIH R01CA085177Jun 1, 2000 - May 31, 2012
    Role: Principal Investigator
    CASPASE 8 AND ITS HOMOLOGS IN NF-KB AND JNK ACTIVATION
    NIH R01AI047230Apr 1, 2000 - Mar 31, 2006
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Combination Therapy With Asciminib and Ponatinib as a Bridge to Brexucabtagene Autoleucel and Maintenance in a Patient With Relapsed Refractory Philadelphia Positive B-Cell Acute Lymphoblastic Leukemia. J Med Cases. 2024 Oct; 15(10):261-266. Amin Muhammad A, Mir Ghazi E, Ali A, Tam E, Woan K, Chaudhary P, Yaghmour G, Ladha A. PMID: 39328803; PMCID: PMC11424108.
      View in: PubMed   Mentions:
    2. Philadelphia-like B-cell acute lymphoblastic Leukaemia: Disease features and outcomes in the era of immunotherapy. Br J Haematol. 2024 Sep 18. Ashouri K, Hom B, Ginosyan AA, Rahimi Y, Resnick K, Nittur V, Hwang J, Ireland R, Ann B, Adnani B, Bragasin EI, Chaudhary P, Ali A, Woan K, Tam EL, Siddiqi I, Ladha A, Yaghmour G. PMID: 39295195.
      View in: PubMed   Mentions:    Fields:    
    3. Graft Versus Host Disease Prophylaxis in Matched Donor Stem Cell Transplantation: Post-transplantation Cyclophosphamide Combinations Versus Methotrexate/Tacrolimus. Transplant Proc. 2024 Aug 21. Ashouri K, Fernandez E, Ginosyan A, Feliciano CM, Hom B, Rodman J, Ali A, Ladha A, Woan K, Tam E, Chaudhary P, Yaghmour G. PMID: 39174390.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Donor matters: Donor selection impact on hematopoietic stem cell transplantation outcomes in Hispanic patients with B-cell acute lymphocytic leukemia: Insights from a myeloablative HSCT study. Leuk Res. 2024 Jun; 141:107501. Ashouri K, Ginosyan AA, Chu M, Hom B, Hwang J, Resnick K, Rahimi Y, Chaudhary P, Woan K, Siddiqi I, Ladha A, Ali A, Tam EL, Yaghmour G. PMID: 38631149.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Post-stem cell transplant maintenance in FLT3mut acute myeloid leukemia - A retrospective analysis: Outcomes are improved with midostaurin but not with gilteritinib. EJHaem. 2024 Apr; 5(2):423-427. Ashouri K, Chennapan K, Martynova A, Nazaretyan S, Ali A, Ginosyan AA, Tam E, Ladha A, Woan K, Chaudhary P, Siddiqi I, Yaghmour G. PMID: 38633126; PMCID: PMC11020142.
      View in: PubMed   Mentions: 1  
    6. Case report: Pulse cyclophosphamide for treatment of multi-agent-refractory hepatic graft-versus-host disease. Front Oncol. 2024; 14:1329893. Cai Y, Ali A, Filler E, Bayati R, Toma T, Zaki O, Yaghmour G, Ladha A, Woan K, Tam E, Chaudhary PM. PMID: 38410106; PMCID: PMC10894980.
      View in: PubMed   Mentions:
    7. Concordance of Next-Generation Sequencing and Multiparametric Flow Cytometry Methods for Detecting Measurable Residual Disease in Adult Acute Lymphoblastic Leukemia: Optimizing Prediction of Clinical Outcomes From a Single-Center Study. Clin Lymphoma Myeloma Leuk. 2024 03; 24(3):e59-e66.e2. Ashouri K, Nittur V, Ginosyan AA, Hwang J, Adnani B, Chen D, Savitala-Damerla L, Schiff K, Chaudhary P, Kovach AE, Ladha A, Siddiqi I, Ali A, Woan K, Tam E, Yaghmour G. PMID: 38061959.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Unique challenges to diagnosing sweet syndrome following induction chemotherapy for relapsed Acute Myeloid Leukemia (AML): A case and brief-review. Respir Med Case Rep. 2023; 46:101922. Nazaretyan S, Ali A, Yaghmour G, Tong A, Castillo V, Rodrigues S, Ladha A, Woan K, Tam E, Shi SY, Bateshansky D, Chaudhary PM. PMID: 37841284; PMCID: PMC10570145.
      View in: PubMed   Mentions:
    9. Expert consensus on microtransplant for acute myeloid leukemia in elderly patients -report from the international microtransplant interest group. Heliyon. 2023 Apr; 9(4):e14924. Ai H, Chao NJ, Rizzieri DA, Huang X, Spitzer TR, Wang J, Guo M, Keating A, Krakow EF, Blaise D, Ma J, Wu D, Reagan J, Gergis U, Duarte RF, Chaudhary PM, Hu K, Yu C, Sun Q, Fuchs E, Cai B, Huang Y, Qiao J, Gottlieb D, Schultz KR, Liu M, Chen X, Chen W, Wang J, Zhang X, Li J, Huang H, Sun Z, Li F, Yang L, Zhang L, Li L, Liu K, Jin J, Liu Q, Liu D, Gao C, Fan C, Wei L, Zhang X, Hu L, Zhang W, Tian Y, Han W, Zhu J, Xiao Z, Zhou D, Zhang B, Jia Y, Zhang Y, Wu X, Shen X, Lu X, Zhan X, Sun X, Xiao Y, Wang J, Shi X, Zheng B, Chen J, Ding B, Wang Z, Zhou F, Zhang M, Zhang Y, Sun J, Xia B, Chen B, Ma L. PMID: 37089296; PMCID: PMC10119710.
      View in: PubMed   Mentions: 1  
    10. Real world experience: Examining outcomes using letermovir for CMV prophylaxis in high-risk allogeneic hematopoietic stem cell patients in the setting of using T-cell depletion as GVHD prophylaxis. Transpl Immunol. 2023 02; 76:101769. Dwabe S, Hsiao M, Ali A, Rodman J, Savitala-Damerla L, Nazaretyan S, Kimberly Schiff NP, Tam E, Ladha A, Woan K, Chaudhary P, Yaghmour G. PMID: 36464218.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    11. Unique Challenges to Diagnosing Human Herpesvirus-6 (HHV-6) Encephalitis Following Post-Hematopoietic Stem Cell Transplant: A Case and Brief Review. Cell Transplant. 2022 Jan-Dec; 31:9636897221119734. Zhu H, Ali A, Woan KV, Tam E, Yaghmour G, Flores A, Chaudhary P. PMID: 36927092; PMCID: PMC9478732.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    12. A novel thermostable beetle luciferase based cytotoxicity assay. Sci Rep. 2021 05 11; 11(1):10002. Choi S, Matta H, Gopalakrishnan R, Natarajan V, Gong S, Jeronimo A, Kuo WY, Bravo B, Chaudhary PM. PMID: 33976304; PMCID: PMC8113442.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    13. The time to offer treatments for COVID-19. Expert Opin Investig Drugs. 2021 May; 30(5):505-518. Ngo BT, Marik P, Kory P, Shapiro L, Thomadsen R, Iglesias J, Ditmore S, Rendell M, Varon J, Dubé M, Nanda N, In G, Arkfeld D, Chaudhary P, Campese VM, Hanna DL, Sawcer DE, Ehresmann G, Peng D, Smogorewski M, Armstrong A, Dasgupta R, Sattler F, Brennan-Rieder D, Mussini C, Mitja O, Soriano V, Peschanski N, Hayem G, Confalonieri M, Piccirillo MC, Lobo-Ferreira A, Bello Rivero I, Turkia M, Vinjevoll EH, Griffin D, Hung IF. PMID: 33721548; PMCID: PMC8074648.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    14. Narciclasine, an isocarbostyril alkaloid, has preferential activity against primary effusion lymphoma. Sci Rep. 2020 03 31; 10(1):5712. Gopalakrishnan R, Matta H, Choi S, Chaudhary PM. PMID: 32235878; PMCID: PMC7109099.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    15. A Fast and Sensitive Luciferase-based Assay for Antibody Engineering and Design of Chimeric Antigen Receptors. Sci Rep. 2020 02 11; 10(1):2318. Natarajan V, Gopalakrishnan R, Matta H, Choi S, Gong S, Jeronimo A, Keerthipati PS, Morales A, Venkatesh H, Chaudhary PM. PMID: 32047180; PMCID: PMC7012821.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    16. A novel luciferase-based assay for the detection of Chimeric Antigen Receptors. Sci Rep. 2019 02 13; 9(1):1957. Gopalakrishnan R, Matta H, Choi S, Natarajan V, Prins R, Gong S, Zenunovic A, Narasappa N, Patel F, Prakash R, Chaudhary V, Sikri V, Chitnis SD, Kochegarov A, Wang D, Falat M, Kahn M, Keerthipati PS, Sharma N, Lenka J, Stieben TM, Braun J, Batra A, Purvis K, Ito K, Lee JH, Jeronimo A, Zamora HM, Membreno A, Qiu Q, Peshin S, Namburu L, Chaudhary PM. PMID: 30760795; PMCID: PMC6374361.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    17. Unrelated HLA mismatched microtransplantation in a patient with refractory secondary acute myeloid leukemia. Leuk Res Rep. 2018; 9:18-20. Punwani N, Merin N, Mohrbacher A, Yaghmour G, Sano A, Ramezani L, Chaudhary PM, Ramsingh G. PMID: 29556468; PMCID: PMC5856665.
      View in: PubMed   Mentions: 3  
    18. Development and characterization of a novel luciferase based cytotoxicity assay. Sci Rep. 2018 01 09; 8(1):199. Matta H, Gopalakrishnan R, Choi S, Prakash R, Natarajan V, Prins R, Gong S, Chitnis SD, Kahn M, Han X, Chaudhary V, Soni A, Sernas J, Khan P, Wang D, Chaudhary PM. PMID: 29317736; PMCID: PMC5760659.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    19. Immunomodulatory drugs target IKZF1-IRF4-MYC axis in primary effusion lymphoma in a cereblon-dependent manner and display synergistic cytotoxicity with BRD4 inhibitors. Oncogene. 2016 Apr 07; 35(14):1797-810. Gopalakrishnan R, Matta H, Tolani B, Triche T, Chaudhary PM. PMID: 26119939; PMCID: PMC4486341.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansAnimalsCells
    20. Toxicity profile of repeated doses of PEG-asparaginase incorporated into a pediatric-type regimen for adult acute lymphoblastic leukemia. Eur J Haematol. 2016 Apr; 96(4):375-80. Aldoss I, Douer D, Behrendt CE, Chaudhary P, Mohrbacher A, Vrona J, Pullarkat V. PMID: 26095294; PMCID: PMC9496150.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    21. DiseaseConnect: a comprehensive web server for mechanism-based disease-disease connections. Nucleic Acids Res. 2014 Jul; 42(Web Server issue):W137-46. Liu CC, Tseng YT, Li W, Wu CY, Mayzus I, Rzhetsky A, Sun F, Waterman M, Chen JJ, Chaudhary PM, Loscalzo J, Crandall E, Zhou XJ. PMID: 24895436; PMCID: PMC4086092.
      View in: PubMed   Mentions: 55     Fields:    Translation:Humans
    22. NEMO is essential for Kaposi's sarcoma-associated herpesvirus-encoded vFLIP K13-induced gene expression and protection against death receptor-induced cell death, and its N-terminal 251 residues are sufficient for this process. J Virol. 2014 Jun; 88(11):6345-54. Tolani B, Matta H, Gopalakrishnan R, Punj V, Chaudhary PM. PMID: 24672029; PMCID: PMC4093867.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    23. A purine scaffold HSP90 inhibitor BIIB021 has selective activity against KSHV-associated primary effusion lymphoma and blocks vFLIP K13-induced NF-κB. Clin Cancer Res. 2013 Sep 15; 19(18):5016-26. Gopalakrishnan R, Matta H, Chaudhary PM. PMID: 23881928; PMCID: PMC3804723.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    24. Targeting Myc in KSHV-associated primary effusion lymphoma with BET bromodomain inhibitors. Oncogene. 2014 May 29; 33(22):2928-37. Tolani B, Gopalakrishnan R, Punj V, Matta H, Chaudhary PM. PMID: 23792448; PMCID: PMC4892892.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    25. Major non-ABO incompatibility caused by anti-Jk(a) in a patient before allogeneic hematopoietic stem cell transplantation. Immunohematology. 2013; 29(1):11-4. Kim MY, Chaudhary P, Shulman IA, Pullarkat V. PMID: 24046917.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    26. Kaposi's sarcoma-associated herpesvirus oncoprotein K13 protects against B cell receptor-induced growth arrest and apoptosis through NF-κB activation. J Virol. 2013 Feb; 87(4):2242-52. Graham C, Matta H, Yang Y, Yi H, Suo Y, Tolani B, Chaudhary PM. PMID: 23236068; PMCID: PMC3571451.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    27. A computational profiling of changes in gene expression and transcription factors induced by vFLIP K13 in primary effusion lymphoma. PLoS One. 2012; 7(5):e37498. Punj V, Matta H, Chaudhary PM. PMID: 22624040; PMCID: PMC3356309.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    28. Kaposi's sarcoma associated herpesvirus encoded viral FLICE inhibitory protein K13 activates NF-κB pathway independent of TRAF6, TAK1 and LUBAC. PLoS One. 2012; 7(5):e36601. Matta H, Gopalakrishnan R, Graham C, Tolani B, Khanna A, Yi H, Suo Y, Chaudhary PM. PMID: 22590573; PMCID: PMC3348130.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    29. Constitutive NF-kappaB activation confers interleukin 6 (IL6) independence and resistance to dexamethasone and Janus kinase inhibitor INCB018424 in murine plasmacytoma cells. J Biol Chem. 2011 Aug 12; 286(32):27988-97. Yang Y, Groshong JS, Matta H, Gopalakrishnan R, Yi H, Chaudhary PM. PMID: 21705340; PMCID: PMC3151044.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    30. A20 is induced by Kaposi sarcoma-associated herpesvirus-encoded viral FLICE inhibitory protein (vFLIP) K13 and blocks K13-induced nuclear factor-kappaB in a negative feedback manner. J Biol Chem. 2011 Jun 17; 286(24):21555-64. Matta H, Gopalakrishnan R, Punj V, Yi H, Suo Y, Chaudhary PM. PMID: 21531730; PMCID: PMC3122214.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    31. Kaposi sarcoma-associated herpesvirus-encoded viral FLICE inhibitory protein (vFLIP) K13 cooperates with Myc to promote lymphoma in mice. Cancer Biol Ther. 2010 Nov 15; 10(10):1033-40. Ahmad A, Groshong JS, Matta H, Schamus S, Punj V, Robinson LJ, Gill PS, Chaudhary PM. PMID: 20818173; PMCID: PMC3047095.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    32. Immune evasion by Kaposi's sarcoma-associated herpesvirus. Future Microbiol. 2010 Sep; 5(9):1349-65. Lee HR, Lee S, Chaudhary PM, Gill P, Jung JU. PMID: 20860481; PMCID: PMC3076960.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    33. Lack of evidence for direct involvement of Merkel cell polyomavirus (MCV) in chronic lymphocytic leukemia (CLL). Blood. 2010 Jun 10; 115(23):4973-4. Tolstov YL, Arora R, Scudiere SC, Busam K, Chaudhary PM, Chang Y, Moore PS. PMID: 20538816; PMCID: PMC2890166.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    34. Induction, regulation, and biologic function of Axl receptor tyrosine kinase in Kaposi sarcoma. Blood. 2010 Jul 15; 116(2):297-305. Liu R, Gong M, Li X, Zhou Y, Gao W, Tulpule A, Chaudhary PM, Jung J, Gill PS. PMID: 20442363; PMCID: PMC2910613.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    35. X-linked ectodermal dysplasia receptor is downregulated in breast cancer via promoter methylation. Clin Cancer Res. 2010 Feb 15; 16(4):1140-8. Punj V, Matta H, Chaudhary PM. PMID: 20145163; PMCID: PMC2822888.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    36. Kaposi's sarcoma-associated herpesvirus-encoded viral FLICE inhibitory protein (vFLIP) K13 suppresses CXCR4 expression by upregulating miR-146a. Oncogene. 2010 Mar 25; 29(12):1835-44. Punj V, Matta H, Schamus S, Tamewitz A, Anyang B, Chaudhary PM. PMID: 20023696; PMCID: PMC2845732.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    37. KSHV-induced notch components render endothelial and mural cell characteristics and cell survival. Blood. 2010 Jan 28; 115(4):887-95. Liu R, Li X, Tulpule A, Zhou Y, Scehnet JS, Zhang S, Lee JS, Chaudhary PM, Jung J, Gill PS. PMID: 19965636; PMCID: PMC2815507.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    38. Human Merkel cell polyomavirus infection I. MCV T antigen expression in Merkel cell carcinoma, lymphoid tissues and lymphoid tumors. Int J Cancer. 2009 Sep 15; 125(6):1243-9. Shuda M, Arora R, Kwun HJ, Feng H, Sarid R, Fernández-Figueras MT, Tolstov Y, Gjoerup O, Mansukhani MM, Swerdlow SH, Chaudhary PM, Kirkwood JM, Nalesnik MA, Kant JA, Weiss LM, Moore PS, Chang Y. PMID: 19499546; PMCID: PMC6388400.
      View in: PubMed   Mentions: 152     Fields:    Translation:HumansCells
    39. Integrated microarray and multiplex cytokine analyses of Kaposi's Sarcoma Associated Herpesvirus viral FLICE Inhibitory Protein K13 affected genes and cytokines in human blood vascular endothelial cells. BMC Med Genomics. 2009 Aug 06; 2:50. Punj V, Matta H, Schamus S, Chaudhary PM. PMID: 19660139; PMCID: PMC2732924.
      View in: PubMed   Mentions: 18     Fields:    
    40. Induction of CCL20 production by Kaposi sarcoma-associated herpesvirus: role of viral FLICE inhibitory protein K13-induced NF-kappaB activation. Blood. 2009 May 28; 113(22):5660-8. Punj V, Matta H, Schamus S, Yang T, Chang Y, Chaudhary PM. PMID: 19324905; PMCID: PMC2689059.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    41. Resolving "kinks" of chemotherapy in melanoma. J Natl Cancer Inst. 2008 Jun 18; 100(12):833-5. Moschos SJ, Chaudhary PM, Kirkwood JM. PMID: 18544737.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    42. A nuclear role for Kaposi's sarcoma-associated herpesvirus-encoded K13 protein in gene regulation. Oncogene. 2008 Sep 04; 27(39):5243-53. Matta H, Punj V, Schamus S, Mazzacurati L, Chen AM, Song R, Yang T, Chaudhary PM. PMID: 18469854.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    43. Proteasome inhibitor Bortezomib induces cell cycle arrest and apoptosis in cell lines derived from Ewing's sarcoma family of tumors and synergizes with TRAIL. Cancer Biol Ther. 2008 Apr; 7(4):603-8. Lu G, Punj V, Chaudhary PM. PMID: 18223318.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    44. Adenoviral-mediated gene transfer of ectodysplasin-A2 results in induction of apoptosis and cell-cycle arrest in osteosarcoma cell lines. Cancer Gene Ther. 2007 Nov; 14(11):927-33. Chang B, Punj V, Shindo M, Chaudhary PM. PMID: 17693991.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    45. In primary effusion lymphoma cells, MYB transcriptional repression is associated with v-FLIP expression during latent KSHV infection while both v-FLIP and v-GPCR become involved during the lytic cycle. Br J Haematol. 2007 Aug; 138(4):487-501. Lacoste V, Nicot C, Gessain A, Valensi F, Gabarre J, Matta H, Chaudhary PM, Mahieux R. PMID: 17659053.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    46. Kaposi's sarcoma-associated herpesvirus (KSHV) oncoprotein K13 bypasses TRAFs and directly interacts with the IkappaB kinase complex to selectively activate NF-kappaB without JNK activation. J Biol Chem. 2007 Aug 24; 282(34):24858-65. Matta H, Mazzacurati L, Schamus S, Yang T, Sun Q, Chaudhary PM. PMID: 17597077.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    47. Induction of spindle cell morphology in human vascular endothelial cells by human herpesvirus 8-encoded viral FLICE inhibitory protein K13. Oncogene. 2007 Mar 08; 26(11):1656-60. Matta H, Surabhi RM, Zhao J, Punj V, Sun Q, Schamus S, Mazzacurati L, Chaudhary PM. PMID: 16936773.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    48. Induction of IL-8 expression by human herpesvirus 8 encoded vFLIP K13 via NF-kappaB activation. Oncogene. 2006 May 04; 25(19):2717-26. Sun Q, Matta H, Lu G, Chaudhary PM. PMID: 16418726.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    49. Constitutive NF-kappaB activation, normal Fas-induced apoptosis, and increased incidence of lymphoma in human herpes virus 8 K13 transgenic mice. Proc Natl Acad Sci U S A. 2005 Sep 06; 102(36):12885-90. Chugh P, Matta H, Schamus S, Zachariah S, Kumar A, Richardson JA, Smith AL, Chaudhary PM. PMID: 16120683; PMCID: PMC1200255.
      View in: PubMed   Mentions: 63     Fields:    Translation:AnimalsCells
    50. Kaposi's sarcoma associated herpes virus-encoded viral FLICE inhibitory protein activates transcription from HIV-1 Long Terminal Repeat via the classical NF-kappaB pathway and functionally cooperates with Tat. Retrovirology. 2005 Feb 15; 2:9. Sun Q, Matta H, Chaudhary PM. PMID: 15713234; PMCID: PMC554086.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    51. The proteasome inhibitor bortezomib (PS-341) inhibits growth and induces apoptosis in primary effusion lymphoma cells. Cancer Biol Ther. 2005 Jan; 4(1):77-82. Matta H, Chaudhary PM. PMID: 15662128.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    52. An evolutionary conserved pathway of nuclear factor-kappaB activation involving caspase-mediated cleavage and N-end rule pathway-mediated degradation of IkappaBalpha. J Biol Chem. 2004 Sep 17; 279(38):39358-65. Rathore N, Matta H, Chaudhary PM. PMID: 15252032.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    53. Activation of alternative NF-kappa B pathway by human herpes virus 8-encoded Fas-associated death domain-like IL-1 beta-converting enzyme inhibitory protein (vFLIP). Proc Natl Acad Sci U S A. 2004 Jun 22; 101(25):9399-404. Matta H, Chaudhary PM. PMID: 15190178; PMCID: PMC438988.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansCells
    54. Aberrant methylation of trail decoy receptor genes is frequent in multiple tumor types. Int J Cancer. 2004 May 01; 109(5):786-92. Shivapurkar N, Toyooka S, Toyooka KO, Reddy J, Miyajima K, Suzuki M, Shigematsu H, Takahashi T, Parikh G, Pass HI, Chaudhary PM, Gazdar AF. PMID: 14999791.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    55. The ectodermal dysplasia receptor represses the Lef-1/beta-catenin-dependent transcription independent of NF-kappaB activation. Biochem Biophys Res Commun. 2004 Feb 27; 315(1):73-8. Shindo M, Chaudhary PM. PMID: 15013427.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    56. The human herpes virus 8-encoded viral FLICE-inhibitory protein induces cellular transformation via NF-kappaB activation. J Biol Chem. 2003 Dec 26; 278(52):52437-45. Sun Q, Zachariah S, Chaudhary PM. PMID: 14563855.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    57. Molecular genetic analysis of human herpes virus 8-encoded viral FLICE inhibitory protein-induced NF-kappaB activation. J Biol Chem. 2003 Dec 26; 278(52):52406-11. Matta H, Sun Q, Moses G, Chaudhary PM. PMID: 14561765.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    58. Use of adeno-associated viral vector for delivery of small interfering RNA. Oncogene. 2003 Aug 28; 22(36):5712-5. Tomar RS, Matta H, Chaudhary PM. PMID: 12944921.
      View in: PubMed   Mentions: 49     Fields:    Translation:Cells
    59. Eiger and its receptor, Wengen, comprise a TNF-like system in Drosophila. Oncogene. 2003 Jul 31; 22(31):4860-7. Kauppila S, Maaty WS, Chen P, Tomar RS, Eby MT, Chapo J, Chew S, Rathore N, Zachariah S, Sinha SK, Abrams JM, Chaudhary PM. PMID: 12894227.
      View in: PubMed   Mentions: 65     Fields:    Translation:AnimalsCells
    60. Use of lentiviral vectors for delivery of small interfering RNA. Cancer Biol Ther. 2003 Mar-Apr; 2(2):206-10. Matta H, Hozayev B, Tomar R, Chugh P, Chaudhary PM. PMID: 12750565.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    61. Loss of expression of death-inducing signaling complex (DISC) components in lung cancer cell lines and the influence of MYC amplification. Oncogene. 2002 Dec 05; 21(55):8510-4. Shivapurkar N, Reddy J, Matta H, Sathyanarayana UG, Huang CX, Toyooka S, Minna JD, Chaudhary PM, Gazdar AF. PMID: 12466971.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    62. Role of MRIT/cFLIP in protection against chemotherapy-induced apoptosis. Cancer Biol Ther. 2002 Nov-Dec; 1(6):652-60. Matta H, Eby MT, Gazdar AF, Chaudhary PM. PMID: 12642689.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    63. The human herpes virus 8-encoded viral FLICE inhibitory protein protects against growth factor withdrawal-induced apoptosis via NF-kappa B activation. Blood. 2003 Mar 01; 101(5):1956-61. Sun Q, Matta H, Chaudhary PM. PMID: 12406869.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    64. Deregulation of caspase 8 and 10 expression in pediatric tumors and cell lines. Cancer Res. 2002 Oct 15; 62(20):5897-901. Harada K, Toyooka S, Shivapurkar N, Maitra A, Reddy JL, Matta H, Miyajima K, Timmons CF, Tomlinson GE, Mastrangelo D, Hay RJ, Chaudhary PM, Gazdar AF. PMID: 12384554.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansCells
    65. Role of TRAF3 and -6 in the activation of the NF-kappa B and JNK pathways by X-linked ectodermal dysplasia receptor. J Biol Chem. 2002 Nov 22; 277(47):44953-61. Sinha SK, Zachariah S, Quiñones HI, Shindo M, Chaudhary PM. PMID: 12270937.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    66. The human herpes virus 8-encoded viral FLICE inhibitory protein physically associates with and persistently activates the Ikappa B kinase complex. J Biol Chem. 2002 Apr 19; 277(16):13745-51. Liu L, Eby MT, Rathore N, Sinha SK, Kumar A, Chaudhary PM. PMID: 11830587.
      View in: PubMed   Mentions: 114     Fields:    Translation:HumansCells
    67. Cytotoxicity of Tumor necrosis factor related apoptosis-inducing ligand towards Ewing's sarcoma cell lines. Oncogene. 2001 Feb 22; 20(8):1010-4. Kumar A, Jasmin A, Eby MT, Chaudhary PM. PMID: 11314037.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    68. Activation of the NF-kappaB pathway by caspase 8 and its homologs. Oncogene. 2000 Sep 14; 19(39):4451-60. Chaudhary PM, Eby MT, Jasmin A, Kumar A, Liu L, Hood L. PMID: 11002417.
      View in: PubMed   Mentions: 92     Fields:    Translation:HumansCells
    69. TAJ, a novel member of the tumor necrosis factor receptor family, activates the c-Jun N-terminal kinase pathway and mediates caspase-independent cell death. J Biol Chem. 2000 May 19; 275(20):15336-42. Eby MT, Jasmin A, Kumar A, Sharma K, Chaudhary PM. PMID: 10809768.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    70. Modulation of the NF-kappa B pathway by virally encoded death effector domains-containing proteins. Oncogene. 1999 Oct 14; 18(42):5738-46. Chaudhary PM, Jasmin A, Eby MT, Hood L. PMID: 10523854.
      View in: PubMed   Mentions: 139     Fields:    Translation:HumansAnimalsCells
    71. Cloning and characterization of two Toll/Interleukin-1 receptor-like genes TIL3 and TIL4: evidence for a multi-gene receptor family in humans. Blood. 1998 Jun 01; 91(11):4020-7. Chaudhary PM, Ferguson C, Nguyen V, Nguyen O, Massa HF, Eby M, Jasmin A, Trask BJ, Hood L, Nelson PS. PMID: 9596645.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    72. Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway. Immunity. 1997 Dec; 7(6):821-30. Chaudhary PM, Eby M, Jasmin A, Bookwalter A, Murray J, Hood L. PMID: 9430227.
      View in: PubMed   Mentions: 184     Fields:    Translation:HumansAnimalsCells
    73. MRIT, a novel death-effector domain-containing protein, interacts with caspases and BclXL and initiates cell death. Proc Natl Acad Sci U S A. 1997 Oct 14; 94(21):11333-8. Han DK, Chaudhary PM, Wright ME, Friedman C, Trask BJ, Riedel RT, Baskin DG, Schwartz SM, Hood L. PMID: 9326610; PMCID: PMC23459.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    74. Expression and activity of the multidrug resistance P-glycoprotein in human peripheral blood lymphocytes. Blood. 1992 Dec 01; 80(11):2735-9. Chaudhary PM, Mechetner EB, Roninson IB. PMID: 1360267.
      View in: PubMed   Mentions: 78     Fields:    Translation:HumansCells
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