Ann F Mohrbacher, MD

Title(s)Associate Professor of Clinical Medicine
SchoolKeck School of Medicine of Usc
Phone+1 323 865 3950
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    Other Positions
    Title(s)Medical Director, Autologous Bone Marrow Transplant

    Title(s)Chair of the Biomedical Institutional Review Board 2


    Collapse Biography 
    Collapse Awards and Honors
    Harvard University 1983A.B. Magna Cum Laude
    Harvard University1983Scholarship
    American Society of Clinical Oncology1995Career Development Award

    Collapse Overview 
    Collapse Overview
    Dr. Mohrbacher, a graduate of Harvard Medical School, is a devoted educator, researcher and medical practitioner. She has several hematology related research interests and activities, including bone marrow transplantation, and has received thousands of dollars in research grants. She has been published in a number of medical journals and has been invited to lecture on topics including Radioimmunotherapy of non-Hodgkin’s lymphoma and B-cell targeted therapy of rheumatoid arthritis. Dr. Mohrbacher is a member of the Southern California Lymphoma Group and currently belongs to a number of university related committees, such as the Post-Graduate Education Committee and the Clinical Investigations Committee.

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Comprehensive Single-Cell Immune Profiling Defines the Patient Multiple Myeloma Microenvironment Following Oncolytic Virus Therapy in a Phase Ib Trial. Clin Cancer Res. 2023 12 15; 29(24):5087-5103. Nawrocki ST, Olea J, Villa Celi C, Dadrastoussi H, Wu K, Tsao-Wei D, Colombo A, Coffey M, Fernandez Hernandez E, Chen X, Nuovo GJ, Carew JS, Mohrbacher AF, Fields P, Kuhn P, Siddiqi I, Merchant A, Kelly KR. PMID: 37812476; PMCID: PMC10722139.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    2. Pembrolizumab plus dinaciclib in patients with hematologic malignancies: the phase 1b KEYNOTE-155 study. Blood Adv. 2022 02 22; 6(4):1232-1242. Gregory GP, Kumar S, Wang D, Mahadevan D, Walker P, Wagner-Johnston N, Escobar C, Bannerji R, Bhutani D, Chang J, Hernandez-Ilizaliturri FJ, Klein A, Pagel JM, Rybka W, Yee AJ, Mohrbacher A, Huang M, Farooqui M, Marinello P, Quach H. PMID: 34972202; PMCID: PMC8864641.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCTClinical Trials
    3. Secondary haematologic malignancies in women with ovarian cancer receiving poly-ADP ribose polymerase inhibitor therapy. Eur J Cancer. 2021 11; 157:59-62. Matsuo K, Klar M, Mohrbacher AF, Roman LD, Wright JD. PMID: 34487985.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    4. Variability in Cytogenetic Testing for Multiple Myeloma: A Comprehensive Analysis From Across the United States. JCO Oncol Pract. 2020 10; 16(10):e1169-e1180. Yu Y, Brown Wade N, Hwang AE, Nooka AK, Fiala MA, Mohrbacher A, Peters ES, Pawlish K, Bock C, Van Den Berg DJ, Rand KA, Stram D, Conti DV, Auclair D, Colditz GA, Mehta J, Haiman CA, Terebelo H, Janakiraman N, Singhal S, Chiu B, Vij R, Bernal-Mizrachi L, Zonder JA, Huff CA, Lonial S, Orlowski RZ, Cozen W, Ailawadhi S. PMID: 32469686; PMCID: PMC7564132.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    5. The Emergence of Epstein-Barr Virus-Related Diffuse Large B-Cell Lymphoma With Mogamulizumab. World J Oncol. 2020 Feb; 11(1):41-43. Wang L, Bargout M, Hon JD, Yaghmour B, Mohrbacher A, Yaghmour G. PMID: 32095189; PMCID: PMC7011905.
      View in: PubMed   Mentions: 1  
    6. A meta-analysis of genome-wide association studies of multiple myeloma among men and women of African ancestry. Blood Adv. 2020 01 14; 4(1):181-190. Du Z, Weinhold N, Song GC, Rand KA, Van Den Berg DJ, Hwang AE, Sheng X, Hom V, Ailawadhi S, Nooka AK, Singhal S, Pawlish K, Peters ES, Bock C, Mohrbacher A, Stram A, Berndt SI, Blot WJ, Casey G, Stevens VL, Kittles R, Goodman PJ, Diver WR, Hennis A, Nemesure B, Klein EA, Rybicki BA, Stanford JL, Witte JS, Signorello L, John EM, Bernstein L, Stroup AM, Stephens OW, Zangari M, Van Rhee F, Olshan A, Zheng W, Hu JJ, Ziegler R, Nyante SJ, Ingles SA, Press MF, Carpten JD, Chanock SJ, Mehta J, Colditz GA, Wolf J, Martin TG, Tomasson M, Fiala MA, Terebelo H, Janakiraman N, Kolonel L, Anderson KC, Le Marchand L, Auclair D, Chiu BC, Ziv E, Stram D, Vij R, Bernal-Mizrachi L, Morgan GJ, Zonder JA, Huff CA, Lonial S, Orlowski RZ, Conti DV, Haiman CA, Cozen W. PMID: 31935283; PMCID: PMC6960456.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    7. Unrelated HLA mismatched microtransplantation in a patient with refractory secondary acute myeloid leukemia. Leuk Res Rep. 2018; 9:18-20. Punwani N, Merin N, Mohrbacher A, Yaghmour G, Sano A, Ramezani L, Chaudhary PM, Ramsingh G. PMID: 29556468; PMCID: PMC5856665.
      View in: PubMed   Mentions: 3  
    8. HLA-Mismatched Microtransplant in Older Patients Newly Diagnosed With Acute Myeloid Leukemia: Results From the Microtransplantation Interest Group. JAMA Oncol. 2018 Jan 01; 4(1):54-62. Guo M, Chao NJ, Li JY, Rizzieri DA, Sun QY, Mohrbacher A, Krakow EF, Sun WJ, Shen XL, Zhan XR, Wu DP, Liu L, Wang J, Zhou M, Yang LH, Bao YY, Dong Z, Cai B, Hu KX, Yu CL, Qiao JH, Zuo HL, Huang YJ, Sung AD, Qiao JX, Liu ZQ, Liu TQ, Yao B, Zhao HX, Qian SX, Liu WW, Forés R, Duarte RF, Ai HS, Microtransplantation Interest Group. PMID: 28910431; PMCID: PMC5833633.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCTClinical Trials
    9. Asian-variant intravascular large B-cell lymphoma. Proc (Bayl Univ Med Cent). 2017 Apr; 30(2):186-189. Su DW, Pasch W, Costales C, Siddiqi I, Mohrbacher A. PMID: 28405077; PMCID: PMC5349823.
      View in: PubMed   Mentions: 3  
    10. A Meta-analysis of Multiple Myeloma Risk Regions in African and European Ancestry Populations Identifies Putatively Functional Loci. Cancer Epidemiol Biomarkers Prev. 2016 12; 25(12):1609-1618. Rand KA, Song C, Dean E, Serie DJ, Curtin K, Sheng X, Hu D, Huff CA, Bernal-Mizrachi L, Tomasson MH, Ailawadhi S, Singhal S, Pawlish K, Peters ES, Bock CH, Stram A, Van Den Berg DJ, Edlund CK, Conti DV, Zimmerman T, Hwang AE, Huntsman S, Graff J, Nooka A, Kong Y, Pregja SL, Berndt SI, Blot WJ, Carpten J, Casey G, Chu L, Diver WR, Stevens VL, Lieber MR, Goodman PJ, Hennis AJ, Hsing AW, Mehta J, Kittles RA, Kolb S, Klein EA, Leske C, Murphy AB, Nemesure B, Neslund-Dudas C, Strom SS, Vij R, Rybicki BA, Stanford JL, Signorello LB, Witte JS, Ambrosone CB, Bhatti P, John EM, Bernstein L, Zheng W, Olshan AF, Hu JJ, Ziegler RG, Nyante SJ, Bandera EV, Birmann BM, Ingles SA, Press MF, Atanackovic D, Glenn MJ, Cannon-Albright LA, Jones B, Tricot G, Martin TG, Kumar SK, Wolf JL, Deming Halverson SL, Rothman N, Brooks-Wilson AR, Rajkumar SV, Kolonel LN, Chanock SJ, Slager SL, Severson RK, Janakiraman N, Terebelo HR, Brown EE, De Roos AJ, Mohrbacher AF, Colditz GA, Giles GG, Spinelli JJ, Chiu BC, Munshi NC, Anderson KC, Levy J, Zonder JA, Orlowski RZ, Lonial S, Camp NJ, Vachon CM, Ziv E, Stram DO, Hazelett DJ, Haiman CA, Cozen W. PMID: 27587788; PMCID: PMC5524541.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    11. Randomized phase 2 study: elotuzumab plus bortezomib/dexamethasone vs bortezomib/dexamethasone for relapsed/refractory MM. Blood. 2016 06 09; 127(23):2833-40. Jakubowiak A, Offidani M, Pégourie B, De La Rubia J, Garderet L, Laribi K, Bosi A, Marasca R, Laubach J, Mohrbacher A, Carella AM, Singhal AK, Tsao LC, Lynch M, Bleickardt E, Jou YM, Robbins M, Palumbo A. PMID: 27091875; PMCID: PMC4900953.
      View in: PubMed   Mentions: 101     Fields:    Translation:HumansCTClinical Trials
    12. Toxicity profile of repeated doses of PEG-asparaginase incorporated into a pediatric-type regimen for adult acute lymphoblastic leukemia. Eur J Haematol. 2016 Apr; 96(4):375-80. Aldoss I, Douer D, Behrendt CE, Chaudhary P, Mohrbacher A, Vrona J, Pullarkat V. PMID: 26095294; PMCID: PMC9496150.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    13. An effective reinduction regimen for first relapse of adult acute lymphoblastic leukemia. Med Oncol. 2013 Dec; 30(4):744. Aldoss I, Pullarkat V, Patel R, Watkins K, Mohrbacher A, Levine AM, Douer D. PMID: 24135867.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    14. Phase I trial of anti-CS1 monoclonal antibody elotuzumab in combination with bortezomib in the treatment of relapsed/refractory multiple myeloma. J Clin Oncol. 2012 Jun 01; 30(16):1960-5. Jakubowiak AJ, Benson DM, Bensinger W, Siegel DS, Zimmerman TM, Mohrbacher A, Richardson PG, Afar DE, Singhal AK, Anderson KC. PMID: 22291084; PMCID: PMC4874204.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCTClinical Trials
    15. A phase 1, multicenter, open-label, dose escalation study of elotuzumab in patients with advanced multiple myeloma. Blood. 2012 Jul 19; 120(3):552-9. Zonder JA, Mohrbacher AF, Singhal S, van Rhee F, Bensinger WI, Ding H, Fry J, Afar DE, Singhal AK. PMID: 22184404; PMCID: PMC4467882.
      View in: PubMed   Mentions: 138     Fields:    Translation:HumansCTClinical Trials
    16. Phase II randomized trial of bevacizumab versus bevacizumab and thalidomide for relapsed/refractory multiple myeloma: a California Cancer Consortium trial. Br J Haematol. 2011 Aug; 154(4):533-5. Somlo G, Lashkari A, Bellamy W, Zimmerman TM, Tuscano JM, O'Donnell MR, Mohrbacher AF, Forman SJ, Frankel P, Chen HX, Doroshow JH, Gandara DR. PMID: 21517811; PMCID: PMC3272081.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCTClinical Trials
    17. A phase I biological study of azacitidine (Vidaza™) to determine the optimal dose to inhibit DNA methylation. Epigenetics. 2010 Nov-Dec; 5(8):750-7. Bernstein I, Byun HM, Mohrbacher A, Douer D, Gorospe G, Hergesheimer J, Groshen S, O'Connell C, Yang AS. PMID: 20861661.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    18. Pharmacokinetic and pharmacodynamic study of two doses of bortezomib in patients with relapsed multiple myeloma. Cancer Chemother Pharmacol. 2011 Jan; 67(1):57-67. Reece DE, Sullivan D, Lonial S, Mohrbacher AF, Chatta G, Shustik C, Burris H, Venkatakrishnan K, Neuwirth R, Riordan WJ, Karol M, von Moltke LL, Acharya M, Zannikos P, Keith Stewart A. PMID: 20306195; PMCID: PMC3951913.
      View in: PubMed   Mentions: 55     Fields:    Translation:Humans
    19. Therapy-related, mixed-lineage leukaemia translocation-positive, monoblastic myeloid sarcoma of the uterus. J Clin Pathol. 2007 May; 60(5):562-4. Pullarkat V, Veliz L, Chang K, Mohrbacher A, Teotico AL, Forman SJ, Slovak ML. PMID: 17513515; PMCID: PMC1994540.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. Pegylated liposomal doxorubicin, vincristine, and dexamethasone provide significant reduction in toxicity compared with doxorubicin, vincristine, and dexamethasone in patients with newly diagnosed multiple myeloma: a Phase III multicenter randomized trial. Cancer. 2006 Feb 15; 106(4):848-58. Rifkin RM, Gregory SA, Mohrbacher A, Hussein MA. PMID: 16404741.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCTClinical Trials
    21. B cell non-Hodgkin's lymphoma: rituximab safety experience. Arthritis Res Ther. 2005; 7 Suppl 3:S19-25. Mohrbacher A. PMID: 15960818; PMCID: PMC2833973.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    22. TRALI due to granulocyte-agglutinating human neutrophil antigen-3a (5b) alloantibodies in donor plasma: a report of 2 fatalities. Transfusion. 2003 May; 43(5):641-5. Davoren A, Curtis BR, Shulman IA, Mohrbacher AF, Bux J, Kwiatkowska BJ, McFarland JG, Aster RH. PMID: 12702187.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    23. Liposomal daunorubicin (DaunoXome) plus dexamethasone for patients with multiple myeloma. A phase II International Oncology Study Group study. Cancer. 2002 May 15; 94(10):2645-52. Mohrbacher AF, Gregory SA, Gabriel DA, Rusk JM, Giles FJ. PMID: 12173332.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    24. Quantitative measure of c-abl and p15 methylation in chronic myelogenous leukemia: biological implications. Blood. 2000 May 01; 95(9):2990-2. Nguyen TT, Mohrbacher AF, Tsai YC, Groffen J, Heisterkamp N, Nichols PW, Yu MC, Lübbert M, Jones PA. PMID: 10779450.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    25. Single-agent monoclonal antibody efficacy in bulky non-Hodgkin's lymphoma: results of a phase II trial of rituximab. J Clin Oncol. 1999 Jun; 17(6):1851-7. Davis TA, White CA, Grillo-López AJ, Velásquez WS, Link B, Maloney DG, Dillman RO, Williams ME, Mohrbacher A, Weaver R, Dowden S, Levy R. PMID: 10561225.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCTClinical Trials
    26. The influence of patient-related factors on ex vivo retroviral-mediated gene transfer into mobilized peripheral blood myeloid progenitors. Hum Gene Ther. 1998 May 01; 9(7):1061-8. Douer D, Ramezani L, Mohrbacher AF, Khan A, Groshen S, Levine AM, Anderson WF. PMID: 9607417.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    27. High-dose chemotherapy and autologous bone marrow plus peripheral blood stem cell transplantation for patients with lymphoma or metastatic breast cancer: use of marker genes to investigate hematopoietic reconstitution in adults. Hum Gene Ther. 1996 Mar 20; 7(5):669-84. Douer D, Levine A, Anderson WF, Gordon M, Groshen S, Khan A, Mohrbacher A, Muggia F, Shibata D. PMID: 8845392.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    28. Adhesion of human myeloma-derived cell lines to bone marrow stromal cells stimulates interleukin-6 secretion. Blood. 1993 Dec 15; 82(12):3712-20. Uchiyama H, Barut BA, Mohrbacher AF, Chauhan D, Anderson KC. PMID: 8260708.
      View in: PubMed   Mentions: 108     Fields:    Translation:HumansCells
    29. Regulation of c-jun gene expression in human T lymphocytes. Blood. 1993 Mar 15; 81(6):1540-8. Chauhan D, Kharbanda SM, Rubin E, Barut BA, Mohrbacher A, Kufe DW, Anderson KC. PMID: 8453101.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    30. Role of interleukin 6 in the growth of myeloma-derived cell lines. Leuk Res. 1992 Oct; 16(10):951-9. Barut BA, Zon LI, Cochran MK, Paul SR, Chauhan D, Mohrbacher A, Fingeroth J, Anderson KC. PMID: 1405708.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
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