Pin Wang, PhD

Title(s)Professor
SchoolViterbi School of Engineering, Bme
AddressRTH 506
University Park Campus
Los Angeles CA 90089-1211
Phone+1 213 740 0780
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    Collapse Overview
    The Wang laboratory focuses on an emerging field of “immunobioengineering” with the aim of employing engineering tools and principles to quantitatively understand the immune system in health and disease and to develop novel molecular and cellular immunotherapies by precisely modulating disease-specific immune responses. The ongoing research research projects include: 1) exploring various strategies to engineer virus-derived vector systems for dendritic cell-targeted vaccine delivery and oncolytic virus-based immunotherapy; 2) designing and optimizing cellular immunotherapy that is based on molecular engineering of chimeric antigen receptors (CARs); 3) exploring immune cells as drug carriers for targeted delivery of immunomodulatory drugs to enhance cancer immunotherapy; 4) exploring systems biology tools for modeling and understanding details of signaling pathways mediated by designer molecules such as chimeric antigen receptors to activate T cells; 5) developing engineering methods to improve adeno-associated virus (AAV)-based gene delivery. In this research laboratory, bioengineers collaborate with chemists, immunologists, computer scientists, and system biologists to directly address problems in translational immunology and develop and optimize innovative approaches to improve lives of patients suffering from cancer and infectious diseases.

    Collapse Research 
    Collapse Research Activities and Funding
    In situ Redirection of T cell Specificity and Imaging of Targeted CAR Expression.
    NIH R01EB017206Sep 1, 2013 - Aug 31, 2020
    Role: Co-Principal Investigator
    SUPR Peptides to Inhibit Undruggable Cancer Target (PQ18)
    NIH R01CA170820Sep 17, 2012 - Jun 30, 2017
    Role: Co-Principal Investigator
    Targeting lentiviruses to infect chosen cells
    NIH R01AI068978Feb 1, 2006 - Jan 31, 2012
    Role: Principal Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Peripheral eosinophil counts predict efficacy of anti-CD19 CAR-T cell therapy against B-lineage non-Hodgkin lymphoma. Theranostics. 2021; 11(10):4699-4709. Jia Q, Qin D, He F, Xie Q, Ying Z, Zhang Y, Song Y, Cheng JN, Zuo X, Xu L, Fang H, Hu C, Peng L, Jin T, Shi Z, Alexander PB, Wang Y, Liu Y, Han W, Zhu J, Wang P, Li QJ, Zhu B. PMID: 33754022; PMCID: PMC7978305.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    2. ERK Activation in CAR T Cells Is Amplified by CD28-Mediated Increase in CD3ζ Phosphorylation. iScience. 2020 Apr 24; 23(4):101023. Rohrs JA, Siegler EL, Wang P, Finley SD. PMID: 32325413; PMCID: PMC7178546.
      View in: PubMed   Mentions: 6  
    3. Donor-Derived CD123-Targeted CAR T Cell Serves as a RIC Regimen for Haploidentical Transplantation in a Patient With FUS-ERG+ AML. Front Oncol. 2019; 9:1358. Yao S, Jianlin C, Yarong L, Botao L, Qinghan W, Hongliang F, Lu Z, Hongmei N, Pin W, Hu C, Liangding H, Bin Z. PMID: 31850234; PMCID: PMC6901822.
      View in: PubMed   Mentions: 7  
    4. Quantitative Proteomics and Metabolomics Reveal Biomarkers of Disease as Potential Immunotherapy Targets and Indicators of Therapeutic Efficacy. Theranostics. 2019; 9(25):7872-7888. MacMullan MA, Dunn ZS, Graham N, Yang L, Wang P. PMID: 31695805; PMCID: PMC6831481.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    5. T cell immunotherapy enhanced by designer biomaterials. Biomaterials. 2019 10; 217:119265. Dunn ZS, Mac J, Wang P. PMID: 31271861; PMCID: PMC6689323.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    6. Inhibition of nucleotide synthesis promotes replicative senescence of human mammary epithelial cells. J Biol Chem. 2019 07 05; 294(27):10564-10578. Delfarah A, Parrish S, Junge JA, Yang J, Seo F, Li S, Mac J, Wang P, Fraser SE, Graham NA. PMID: 31138644; PMCID: PMC6615688.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    7. Evaluating CAR-T Cell Therapy in a Hypoxic 3D Tumor Model. Adv Healthc Mater. 2019 03; 8(5):e1900001. Ando Y, Siegler EL, Ta HP, Cinay GE, Zhou H, Gorrell KA, Au H, Jarvis BM, Wang P, Shen K. PMID: 30734529; PMCID: PMC6448565.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    8. Understanding the Dynamics of T-Cell Activation in Health and Disease Through the Lens of Computational Modeling. JCO Clin Cancer Inform. 2019 01; 3:1-8. Rohrs JA, Wang P, Finley SD. PMID: 30689404; PMCID: PMC6593125.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    9. Computational Model of Chimeric Antigen Receptors Explains Site-Specific Phosphorylation Kinetics. Biophys J. 2018 09 18; 115(6):1116-1129. Rohrs JA, Zheng D, Graham NA, Wang P, Finley SD. PMID: 30197180; PMCID: PMC6139883.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    10. Off-the-Shelf CAR-NK Cells for Cancer Immunotherapy. Cell Stem Cell. 2018 08 02; 23(2):160-161. Siegler EL, Zhu Y, Wang P, Yang L. PMID: 30075127.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    11. TAK1 mediates microenvironment-triggered autocrine signals and promotes triple-negative breast cancer lung metastasis. Nat Commun. 2018 05 18; 9(1):1994. Iriondo O, Liu Y, Lee G, Elhodaky M, Jimenez C, Li L, Lang J, Wang P, Yu M. PMID: 29777109; PMCID: PMC5959931.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    12. CAR-T Cells Surface-Engineered with Drug-Encapsulated Nanoparticles Can Ameliorate Intratumoral T-cell Hypofunction. Cancer Immunol Res. 2018 07; 6(7):812-824. Siriwon N, Kim YJ, Siegler E, Chen X, Rohrs JA, Liu Y, Wang P. PMID: 29720380.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    13. Preclinical Models in Chimeric Antigen Receptor-Engineered T-Cell Therapy. Hum Gene Ther. 2018 05; 29(5):534-546. Siegler EL, Wang P. PMID: 29390873.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    14. In Vivo Expansion and Antitumor Activity of Coinfused CD28- and 4-1BB-Engineered CAR-T Cells in Patients with B Cell Leukemia. Mol Ther. 2018 04 04; 26(4):976-985. Cheng Z, Wei R, Ma Q, Shi L, He F, Shi Z, Jin T, Xie R, Wei B, Chen J, Fang H, Han X, Rohrs JA, Bryson P, Liu Y, Li QJ, Zhu B, Wang P. PMID: 29503204; PMCID: PMC6079368.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    15. Enhanced Cancer Immunotherapy by Chimeric Antigen Receptor-Modified T Cells Engineered to Secrete Checkpoint Inhibitors. Clin Cancer Res. 2017 Nov 15; 23(22):6982-6992. Li S, Siriwon N, Zhang X, Yang S, Jin T, He F, Kim YJ, Mac J, Lu Z, Wang S, Han X, Wang P. PMID: 28912137.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansAnimalsCells
    16. Breast cancer vaccines delivered by dendritic cell-targeted lentivectors induce potent antitumor immune responses and protect mice from mammary tumor growth. Vaccine. 2017 10 13; 35(43):5842-5849. Bryson PD, Han X, Truong N, Wang P. PMID: 28916248; PMCID: PMC5624555.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    17. Combination Cancer Therapy Using Chimeric Antigen Receptor-Engineered Natural Killer Cells as Drug Carriers. Mol Ther. 2017 Dec 06; 25(12):2607-2619. Siegler EL, Kim YJ, Chen X, Siriwon N, Mac J, Rohrs JA, Bryson PD, Wang P. PMID: 28919377; PMCID: PMC5768663.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    18. Dendritic cell-targeted lentiviral vector immunization uses pseudotransduction and DNA-mediated STING and cGAS activation. Sci Immunol. 2017 Jul 21; 2(13). Kim JT, Liu Y, Kulkarni RP, Lee KK, Dai B, Lovely G, Ouyang Y, Wang P, Yang L, Baltimore D. PMID: 28733470; PMCID: PMC5845465.
      View in: PubMed   Mentions: 4     Fields:    
    19. Adnectin-Based Design of Chimeric Antigen Receptor for T Cell Engineering. Mol Ther. 2017 11 01; 25(11):2466-2476. Han X, Cinay GE, Zhao Y, Guo Y, Zhang X, Wang P. PMID: 28784559; PMCID: PMC5675441.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    20. Designed Ankyrin Repeat Proteins as Her2 Targeting Domains in Chimeric Antigen Receptor-Engineered T Cells. Hum Gene Ther. 2017 09; 28(9):726-736. Siegler E, Li S, Kim YJ, Wang P. PMID: 28796529; PMCID: PMC5582591.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    21. Co-delivery of carboplatin and paclitaxel via cross-linked multilamellar liposomes for ovarian cancer treatment. RSC Adv. 2017 Apr 03; 7(32):19685-19693. Zhang X, Liu Y, Kim YJ, Mac J, Zhuang R, Wang P. PMID: 28603607; PMCID: PMC5450007.
      View in: PubMed   Mentions: 6  
    22. Masked Chimeric Antigen Receptor for Tumor-Specific Activation. Mol Ther. 2017 01 04; 25(1):274-284. Han X, Bryson PD, Zhao Y, Cinay GE, Li S, Guo Y, Siriwon N, Wang P. PMID: 28129121; PMCID: PMC5363190.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    23. Directed Evolution of Scanning Unnatural-Protease-Resistant (SUPR) Peptides for in Vivo Applications. Chembiochem. 2016 09 02; 17(17):1643-51. Fiacco SV, Kelderhouse LE, Hardy A, Peleg Y, Hu B, Ornelas A, Yang P, Gammon ST, Howell SM, Wang P, Takahashi TT, Millward SW, Roberts RW. PMID: 27465925; PMCID: PMC5167532.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    24. Predictive Model of Lymphocyte-Specific Protein Tyrosine Kinase (LCK) Autoregulation. Cell Mol Bioeng. 2016; 9:351-367. Rohrs JA, Wang P, Finley SD. PMID: 27547268; PMCID: PMC4978775.
      View in: PubMed   Mentions: 10  
    25. A multi-antigen vaccine in combination with an immunotoxin targeting tumor-associated fibroblast for treating murine melanoma. Mol Ther Oncolytics. 2016; 3:16007. Fang J, Hu B, Li S, Zhang C, Liu Y, Wang P. PMID: 27119119; PMCID: PMC4824564.
      View in: PubMed   Mentions: 10  
    26. A potent immunotoxin targeting fibroblast activation protein for treatment of breast cancer in mice. Int J Cancer. 2016 Feb 15; 138(4):1013-23. Fang J, Xiao L, Joo KI, Liu Y, Zhang C, Liu S, Conti PS, Li Z, Wang P. PMID: 26334777; PMCID: PMC4715643.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    27. Co-Eradication of Breast Cancer Cells and Cancer Stem Cells by Cross-Linked Multilamellar Liposomes Enhances Tumor Treatment. Mol Pharm. 2015 Aug 03; 12(8):2811-22. Kim YJ, Liu Y, Li S, Rohrs J, Zhang R, Zhang X, Wang P. PMID: 26098197.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    28. Generation of Targeted Adeno-Associated Virus (AAV) Vectors for Human Gene Therapy. Curr Pharm Des. 2015; 21(22):3248-56. Liu Y, Siriwon N, Rohrs JA, Wang P. PMID: 26027561.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    29. Pseudotyping lentiviral vectors with lymphocytic choriomeningitis virus glycoproteins for transduction of dendritic cells and in vivo immunization. Hum Gene Ther Methods. 2014 Dec; 25(6):328-38. Zhang C, Hu B, Xiao L, Liu Y, Wang P. PMID: 25416034; PMCID: PMC4268581.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    30. Codelivery of chemotherapeutics via crosslinked multilamellar liposomal vesicles to overcome multidrug resistance in tumor. PLoS One. 2014; 9(10):e110611. Liu Y, Fang J, Joo KI, Wong MK, Wang P. PMID: 25330237; PMCID: PMC4201570.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    31. Clickable protein nanocapsules for targeted delivery of recombinant p53 protein. J Am Chem Soc. 2014 Oct 29; 136(43):15319-25. Zhao M, Liu Y, Hsieh RS, Wang N, Tai W, Joo KI, Wang P, Gu Z, Tang Y. PMID: 25289975.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    32. In situ modulation of dendritic cells by injectable thermosensitive hydrogels for cancer vaccines in mice. Biomacromolecules. 2014 Oct 13; 15(10):3836-45. Liu Y, Xiao L, Joo KI, Hu B, Fang J, Wang P. PMID: 25207465; PMCID: PMC4195289.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    33. Serum stable natural peptides designed by mRNA display. Sci Rep. 2014 Sep 19; 4:6008. Howell SM, Fiacco SV, Takahashi TT, Jalali-Yazdi F, Millward SW, Hu B, Wang P, Roberts RW. PMID: 25234472; PMCID: PMC4168267.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    34. Codelivery of doxorubicin and paclitaxel by cross-linked multilamellar liposome enables synergistic antitumor activity. Mol Pharm. 2014 May 05; 11(5):1651-61. Liu Y, Fang J, Kim YJ, Wong MK, Wang P. PMID: 24673622; PMCID: PMC4018157.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    35. Enhancing gene delivery of adeno-associated viruses by cell-permeable peptides. Mol Ther Methods Clin Dev. 2014; 1:12. Liu Y, Kim YJ, Ji M, Fang J, Siriwon N, Zhang LI, Wang P. PMID: 26015948; PMCID: PMC4365833.
      View in: PubMed   Mentions: 17  
    36. Passive immunization against HIV/AIDS by antibody gene transfer. Viruses. 2014 Jan 27; 6(2):428-47. Yang L, Wang P. PMID: 24473340; PMCID: PMC3939464.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    37. Visualization of intracellular pathways of engineered baculovirus in mammalian cells. Virus Res. 2014 Mar 06; 181:81-91. Liu Y, Joo KI, Lei Y, Wang P. PMID: 24457070; PMCID: PMC4439417.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    38. Advances and challenges in the use of nanoparticles to optimize PK/PD interactions of combined anti-cancer therapies. Curr Drug Metab. 2014; 15(8):818-28. Liu Y, Rohrs J, Wang P. PMID: 25705903.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    39. Synthetic niches for differentiation of human embryonic stem cells bypassing embryoid body formation. J Biomed Mater Res B Appl Biomater. 2014 Jul; 102(5):1101-12. Liu Y, Fox V, Lei Y, Hu B, Joo KI, Wang P. PMID: 24327412.
      View in: PubMed   Mentions: 4  Translation:HumansCells
    40. Visualization of DC-SIGN-mediated entry pathway of engineered lentiviral vectors in target cells. PLoS One. 2013; 8(6):e67400. Liu Y, Tai A, Joo KI, Wang P. PMID: 23840690; PMCID: PMC3696072.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    41. A tetracycline-regulated cell line produces high-titer lentiviral vectors that specifically target dendritic cells. J Vis Exp. 2013 Jun 19; (76). Bryson PD, Zhang C, Lee CL, Wang P. PMID: 23851977; PMCID: PMC3727697.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    42. Enhanced therapeutic efficacy of iRGD-conjugated crosslinked multilayer liposomes for drug delivery. Biomed Res Int. 2013; 2013:378380. Liu Y, Ji M, Wong MK, Joo KI, Wang P. PMID: 23691500; PMCID: PMC3652104.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    43. Antibody-mimetic ligand selected by mRNA display targets DC-SIGN for dendritic cell-directed antigen delivery. ACS Chem Biol. 2013 May 17; 8(5):967-77. Xiao L, Hung KC, Takahashi TT, Joo KI, Lim M, Roberts RW, Wang P. PMID: 23427768.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    44. Genome mining of a prenylated and immunosuppressive polyketide from pathogenic fungi. Org Lett. 2013 Feb 15; 15(4):780-3. Chooi YH, Fang J, Liu H, Filler SG, Wang P, Tang Y. PMID: 23368997; PMCID: PMC3576815.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    45. Crosslinked multilamellar liposomes for controlled delivery of anticancer drugs. Biomaterials. 2013 Apr; 34(12):3098-109. Joo KI, Xiao L, Liu S, Liu Y, Lee CL, Conti PS, Wong MK, Li Z, Wang P. PMID: 23375392; PMCID: PMC3995748.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    46. Dendritic cell-directed vaccination with a lentivector encoding PSCA for prostate cancer in mice. PLoS One. 2012; 7(11):e48866. Xiao L, Joo KI, Lim M, Wang P. PMID: 23139820; PMCID: PMC3490948.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCellsPHPublic Health
    47. Site-specific modification of adeno-associated viruses via a genetically engineered aldehyde tag. Small. 2013 Feb 11; 9(3):421-9. Liu Y, Fang Y, Zhou Y, Zandi E, Lee CL, Joo KI, Wang P. PMID: 23038676.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    48. Discovery and characterization of a group of fungal polycyclic polyketide prenyltransferases. J Am Chem Soc. 2012 Jun 06; 134(22):9428-37. Chooi YH, Wang P, Fang J, Li Y, Wu K, Wang P, Tang Y. PMID: 22590971; PMCID: PMC3904230.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    49. Endocytic processing of adeno-associated virus type 8 vectors for transduction of target cells. Gene Ther. 2013 Mar; 20(3):308-17. Liu Y, Joo KI, Wang P. PMID: 22622241.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    50. PD-1/PD-L1 blockade can enhance HIV-1 Gag-specific T cell immunity elicited by dendritic cell-directed lentiviral vaccines. Mol Ther. 2012 Sep; 20(9):1800-9. Dai B, Xiao L, Bryson PD, Fang J, Wang P. PMID: 22588271; PMCID: PMC3437589.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    51. A TLR4 agonist synergizes with dendritic cell-directed lentiviral vectors for inducing antigen-specific immune responses. Vaccine. 2012 Mar 28; 30(15):2570-81. Xiao L, Kim J, Lim M, Dai B, Yang L, Reed SG, Baltimore D, Wang P. PMID: 22314134; PMCID: PMC3360926.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    52. Construction of stable producer cells to make high-titer lentiviral vectors for dendritic cell-based vaccination. Biotechnol Bioeng. 2012 Jun; 109(6):1551-60. Lee CL, Chou M, Dai B, Xiao L, Wang P. PMID: 22179950; PMCID: PMC3330149.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCellsPHPublic Health
    53. Engineered lentiviral vectors pseudotyped with a CD4 receptor and a fusogenic protein can target cells expressing HIV-1 envelope proteins. Virus Res. 2011 Sep; 160(1-2):340-50. Lee CL, Dang J, Joo KI, Wang P. PMID: 21802459; PMCID: PMC3495169.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    54. Virus-receptor mediated transduction of dendritic cells by lentiviruses enveloped with glycoproteins derived from Semliki Forest virus. PLoS One. 2011; 6(6):e21491. Froelich S, Tai A, Kennedy K, Zubair A, Wang P. PMID: 21738680; PMCID: PMC3124512.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    55. Pseudotyping lentiviral vectors with aura virus envelope glycoproteins for DC-SIGN-mediated transduction of dendritic cells. Hum Gene Ther. 2011 Oct; 22(10):1281-91. Froelich S, Tai A, Kennedy K, Zubair A, Wang P. PMID: 21452926; PMCID: PMC3205794.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    56. Redox-responsive nanocapsules for intracellular protein delivery. Biomaterials. 2011 Aug; 32(22):5223-30. Zhao M, Biswas A, Hu B, Joo KI, Wang P, Gu Z, Tang Y. PMID: 21514660.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    57. Enhanced real-time monitoring of adeno-associated virus trafficking by virus-quantum dot conjugates. ACS Nano. 2011 May 24; 5(5):3523-35. Joo KI, Fang Y, Liu Y, Xiao L, Gu Z, Tai A, Lee CL, Tang Y, Wang P. PMID: 21473596; PMCID: PMC3132586.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    58. Dendritic cell-directed lentivector vaccine induces antigen-specific immune responses against murine melanoma. Cancer Gene Ther. 2011 May; 18(5):370-80. Yang HG, Hu BL, Xiao L, Wang P. PMID: 21372855.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    59. Gene editing of human embryonic stem cells via an engineered baculoviral vector carrying zinc-finger nucleases. Mol Ther. 2011 May; 19(5):942-50. Lei Y, Lee CL, Joo KI, Zarzar J, Liu Y, Dai B, Fox V, Wang P. PMID: 21326219; PMCID: PMC3098635.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    60. Production of lentiviral vectors with enhanced efficiency to target dendritic cells by attenuating mannosidase activity of mammalian cells. J Biol Eng. 2011 Jan 28; 5(1):1. Tai A, Froelich S, Joo KI, Wang P. PMID: 21276219; PMCID: PMC3039557.
      View in: PubMed   Mentions: 4  
    61. Endoprotease-mediated intracellular protein delivery using nanocapsules. ACS Nano. 2011 Feb 22; 5(2):1385-94. Biswas A, Joo KI, Liu J, Zhao M, Fan G, Wang P, Gu Z, Tang Y. PMID: 21268592.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    62. Immunization delivered by lentiviral vectors for cancer and infectious diseases. Immunol Rev. 2011 Jan; 239(1):45-61. Hu B, Tai A, Wang P. PMID: 21198664; PMCID: PMC3030993.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    63. Batch fabrication of high-performance planar patch-clamp devices in quartz. Adv Mater. 2010 Nov 02; 22(41):4622-7. Nagarah JM, Paek E, Luo Y, Wang P, Hwang GS, Heath JR. PMID: 20830714.
      View in: PubMed   Mentions: 6  
    64. Imaging multiple intermediates of single-virus membrane fusion mediated by distinct fusion proteins. Microsc Res Tech. 2010 Sep; 73(9):886-900. Joo KI, Tai A, Lee CL, Wong C, Wang P. PMID: 20232362; PMCID: PMC2930027.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    65. Vaccines delivered by integration-deficient lentiviral vectors targeting dendritic cells induces strong antigen-specific immunity. Vaccine. 2010 Sep 24; 28(41):6675-83. Hu B, Dai B, Wang P. PMID: 20709004; PMCID: PMC2956406.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    66. Probing protease activity by single-fluorescent-protein nanocapsules. Chem Commun (Camb). 2010 Sep 21; 46(35):6467-9. Gu Z, Biswas A, Joo KI, Hu B, Wang P, Tang Y. PMID: 20657917.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    67. Lentiviral vectors for immune cells targeting. Immunopharmacol Immunotoxicol. 2010 Jun; 32(2):208-18. Froelich S, Tai A, Wang P. PMID: 20085508; PMCID: PMC2864798.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    68. Targeting lentiviral vector to specific cell types through surface displayed single chain antibody and fusogenic molecule. Virol J. 2010 Feb 11; 7:35. Lei Y, Joo KI, Zarzar J, Wong C, Wang P. PMID: 20149250; PMCID: PMC2830192.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    69. Protein nanocapsule weaved with enzymatically degradable polymeric network. Nano Lett. 2009 Dec; 9(12):4533-8. Gu Z, Yan M, Hu B, Joo KI, Biswas A, Huang Y, Lu Y, Wang P, Tang Y. PMID: 19995089.
      View in: PubMed   Mentions: 26  Translation:HumansCells
    70. Nonintegrating lentiviral vectors can effectively deliver ovalbumin antigen for induction of antitumor immunity. Hum Gene Ther. 2009 Dec; 20(12):1652-64. Hu B, Yang H, Dai B, Tai A, Wang P. PMID: 19663564; PMCID: PMC2799785.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    71. HIV-1 Gag-specific immunity induced by a lentivector-based vaccine directed to dendritic cells. Proc Natl Acad Sci U S A. 2009 Dec 01; 106(48):20382-7. Dai B, Yang L, Yang H, Hu B, Baltimore D, Wang P. PMID: 19918062; PMCID: PMC2777969.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    72. Introduction of an aliphatic ketone into recombinant proteins in a bacterial strain that overexpresses an editing-impaired leucyl-tRNA synthetase. Chembiochem. 2009 Sep 04; 10(13):2188-90. Tang Y, Wang P, Van Deventer JA, Link AJ, Tirrell DA. PMID: 19670197; PMCID: PMC3184883.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
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