Paul S. Gaynon, MD

Title(s)Professor of Pediatrics
SchoolKeck School of Medicine of Usc
AddressCHL Mail Stop 54
Off Campus
Los Angeles CA 90089
Phone+1 323 361 2163
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    CHILDRENS CANCER GROUP
    NIH U10CA005436Dec 1, 1978 - Nov 30, 1998
    Role: Co-Principal Investigator
    CHILDRENS CANCER GROUP
    NIH U10CA002649Dec 1, 1976 - Nov 30, 2002
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Development of second genetically distinct T-lymphoblastic leukemia in a pediatric patient. Pediatr Blood Cancer. 2024 Aug; 71(8):e31050. Hultquist H, Rodriguez A, Ferreira JE, Placek A, Miller KP, Wood BL, Bhojwani D, Kapoor N, Raca G, Gaynon P, Kovach AE. PMID: 38736199; PMCID: PMC11208117.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Efficacy and safety of FLAG-IDA as front-line therapy in de novo paediatric acute myeloid leukaemia population. Br J Haematol. 2023 07; 202(1):e3-e6. Doan A, Huang HKT, Hadar AJ, Malvar J, Rushing T, Raca G, Kovach AE, Freyer DR, Parekh C, Stokke J, Posch LC, Dao J, Bhojwani D, Gaynon P, Orgel E. PMID: 37129267; PMCID: PMC10330637.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Temsirolimus combined with cyclophosphamide and etoposide for pediatric patients with relapsed/refractory acute lymphoblastic leukemia: a Therapeutic Advances in Childhood Leukemia Consortium trial (TACL 2014-001). Haematologica. 2022 10 01; 107(10):2295-2303. Tasian SK, Silverman LB, Whitlock JA, Sposto R, Loftus JP, Schafer ES, Schultz KR, Hutchinson RJ, Gaynon PS, Orgel E, Bateman CM, Cooper TM, Laetsch TW, Sulis ML, Chi YY, Malvar J, Wayne AS, Rheingold SR. PMID: 35112552; PMCID: PMC9521241.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    4. Nelarabine, etoposide, and cyclophosphamide in relapsed pediatric T-acute lymphoblastic leukemia and T-lymphoblastic lymphoma (study T2008-002 NECTAR). Pediatr Blood Cancer. 2022 Nov; 69(11):e29901. Whitlock JA, Malvar J, Dalla-Pozza L, Goldberg JM, Silverman LB, Ziegler DS, Attarbaschi A, Brown PA, Gardner RA, Gaynon PS, Hutchinson R, Huynh VT, Jeha S, Marcus L, Messinger Y, Schultz KR, Cassar J, Locatelli F, Zwaan CM, Wood BL, Sposto R, Gore L. PMID: 35989458.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    5. Survival of pediatric Hodgkin lymphoma patients treated with doxorubicin, bleomycin, vincristine, etoposide, prednisone, and cyclophosphamide (ABVE-PC) versus doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD) at a single institution. Pediatr Blood Cancer. 2022 05; 69(5):e29601. de Armas S, Huertas-Ayala C, Chan RY, Chi YY, Huh WW, Termuhlen A, Gaynon PS, Kovach AE, Doan A. PMID: 35187850; PMCID: PMC10257525.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Acute myeloid leukemia with t(X;6)9p11;q23);MYB-GATA1 and female sex: GATA1 insufficiency may be insufficient for pathogenesis. Cancer Genet. 2022 01; 260-261:37-40. Kovach AE, Zerkalenkova E, Zemtsova L, Borkovskaya A, Gaskova M, Kazanov M, Popov A, Baidun L, Maschan M, Maschan A, Gaynon PS, Bhojwani D, Novichkova G, Olshanskaya Y, Raca G. PMID: 34915342.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    7. A new standard of care for childhood T-cell acute lymphoblastic leukemia? Pediatr Blood Cancer. 2021 10; 68(10):e29238. Gaynon PS, Parekh C. PMID: 34302711.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    8. Preexisting or therapy-induced mutations in relapsed acute lymphoblastic leukemia? Blood. 2020 11 05; 136(19):2233-2235. Gaynon PS, Orgel E, Ji L. PMID: 32603411.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    9. A phase I study of panobinostat in children with relapsed and refractory hematologic malignancies. Pediatr Hematol Oncol. 2020 Sep; 37(6):465-474. Goldberg J, Sulis ML, Bender J, Jeha S, Gardner R, Pollard J, Aquino V, Laetsch T, Winick N, Fu C, Marcus L, Sun W, Verma A, Burke M, Ho P, Manley T, Mody R, Tcheng W, Thomson B, Park J, Sposto R, Messinger Y, Hijiya N, Gaynon P, Barredo J. PMID: 32338562.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCTClinical Trials
    10. Decitabine and Vorinostat with Chemotherapy in Relapsed Pediatric Acute Lymphoblastic Leukemia: A TACL Pilot Study. Clin Cancer Res. 2020 05 15; 26(10):2297-2307. Burke MJ, Kostadinov R, Sposto R, Gore L, Kelley SM, Rabik C, Trepel JB, Lee MJ, Yuno A, Lee S, Bhojwani D, Jeha S, Chang BH, Sulis ML, Hermiston ML, Gaynon P, Huynh V, Verma A, Gardner R, Heym KM, Dennis RM, Ziegler DS, Laetsch TW, Oesterheld JE, Dubois SG, Pollard JA, Glade-Bender J, Cooper TM, Kaplan JA, Farooqi MS, Yoo B, Guest E, Wayne AS, Brown PA. PMID: 31969338; PMCID: PMC7477726.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCTClinical Trials
    11. Methotrexate and asparaginase: not so simple. Leuk Lymphoma. 2019 12; 60(12):2849-2850. Gaynon PS. PMID: 31558076.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Excellent long-term survival of children with Down syndrome and standard-risk ALL: a report from the Children's Oncology Group. Blood Adv. 2019 06 11; 3(11):1647-1656. Matloub Y, Rabin KR, Ji L, Devidas M, Hitzler J, Xu X, Bostrom BC, Stork LC, Winick N, Gastier-Foster JM, Heerema NA, Stonerock E, Carroll WL, Hunger SP, Gaynon PS. PMID: 31160295; PMCID: PMC6560340.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCTClinical Trials
    13. Treatment of higher risk acute lymphoblastic leukemia in young people (CCG-1961), long-term follow-up: a report from the Children's Oncology Group. Leukemia. 2019 09; 33(9):2144-2154. Steinherz PG, Seibel NL, Sather H, Ji L, Xu X, Devidas M, Gaynon PS. PMID: 30816331; PMCID: PMC6713627.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    14. Improved Survival for Children and Young Adults With T-Lineage Acute Lymphoblastic Leukemia: Results From the Children's Oncology Group AALL0434 Methotrexate Randomization. J Clin Oncol. 2018 10 10; 36(29):2926-2934. Winter SS, Dunsmore KP, Devidas M, Wood BL, Esiashvili N, Chen Z, Eisenberg N, Briegel N, Hayashi RJ, Gastier-Foster JM, Carroll AJ, Heerema NA, Asselin BL, Gaynon PS, Borowitz MJ, Loh ML, Rabin KR, Raetz EA, Zweidler-Mckay PA, Winick NJ, Carroll WL, Hunger SP. PMID: 30138085; PMCID: PMC6366301.
      View in: PubMed   Mentions: 97     Fields:    Translation:Humans
    15. Myeloid lineage switch following chimeric antigen receptor T-cell therapy in a patient with TCF3-ZNF384 fusion-positive B-lymphoblastic leukemia. Pediatr Blood Cancer. 2018 09; 65(9):e27265. Oberley MJ, Gaynon PS, Bhojwani D, Pulsipher MA, Gardner RA, Hiemenz MC, Ji J, Han J, O'Gorman MRG, Wayne AS, Raca G. PMID: 29797659; PMCID: PMC7469918.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    16. First pediatric experience of SL-401, a CD123-targeted therapy, in patients with blastic plasmacytoid dendritic cell neoplasm: report of three cases. J Hematol Oncol. 2018 05 02; 11(1):61. Sun W, Liu H, Kim Y, Karras N, Pawlowska A, Toomey D, Kyono W, Gaynon P, Rosenthal J, Stein A. PMID: 29720227; PMCID: PMC5932872.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    17. Outcome of children with multiply relapsed B-cell acute lymphoblastic leukemia: a therapeutic advances in childhood leukemia & lymphoma study. Leukemia. 2018 11; 32(11):2316-2325. Sun W, Malvar J, Sposto R, Verma A, Wilkes JJ, Dennis R, Heym K, Laetsch TW, Widener M, Rheingold SR, Oesterheld J, Hijiya N, Sulis ML, Huynh V, Place AE, Bittencourt H, Hutchinson R, Messinger Y, Chang B, Matloub Y, Ziegler DS, Gardner R, Cooper T, Ceppi F, Hermiston M, Dalla-Pozza L, Schultz KR, Gaynon P, Wayne AS, Whitlock JA. PMID: 29728694; PMCID: PMC6224404.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    18. A phase 1 study of azacitidine combined with chemotherapy in childhood leukemia: a report from the TACL consortium. Blood. 2018 03 08; 131(10):1145-1148. Sun W, Triche T, Malvar J, Gaynon P, Sposto R, Yang X, Bittencourt H, Place AE, Messinger Y, Fraser C, Dalla-Pozza L, Salhia B, Jones P, Wayne AS, Gore L, Cooper TM, Liang G. PMID: 29339403; PMCID: PMC5863703.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCTClinical Trials
    19. Remission is good - relapse is bad. Haematologica. 2018 01; 103(1):4-5. Gaynon PS. PMID: 29290629; PMCID: PMC5777185.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    20. Redefining treatment failure for pediatric acute leukemia in the era of minimal residual disease testing. Pediatr Hematol Oncol. 2017 Sep - Oct; 34(6-7):395-408. Huynh V, Laetsch TW, Schore RJ, Gaynon P, O'Brien MM. PMID: 29190162.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    21. Therapeutic Advances in Childhood Leukemia and Lymphoma (TACL): Overview and introduction to the proceedings of the 2016 TACL investigator meeting. Pediatr Hematol Oncol. 2017 Sep - Oct; 34(6-7):349-354. Wayne AS, Shin-Kashiyama E, Sposto R, Gaynon P. PMID: 29120691; PMCID: PMC6122960.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    22. A neoplasm with FIP1L1-PDGFRA fusion presenting as pediatric T-cell lymphoblastic leukemia/lymphoma without eosinophilia. Cancer Genet. 2017 Oct; 216-217:91-99. Oberley MJ, Denton C, Ji J, Hiemenz M, Bhojwani D, Ostrow D, Wu S, Gaynon P, Raca G. PMID: 29025601; PMCID: PMC7469920.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    23. Mercaptopurine in childhood acute lymphoblastic leukaemia. Lancet Oncol. 2017 04; 18(4):425-426. Gaynon PS. PMID: 28258829.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    24. Historical Controls? Haematologica. 2017 03; 102(3):e117. Gaynon PS. PMID: 28250008; PMCID: PMC5394945.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    25. "The Second Time is Sweeter After All". Br J Haematol. 2017 02; 176(4):511-512. Gaynon PS. PMID: 28145575.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    26. Bortezomib, Dexamethasone, Mitoxantrone, and Vinorelbine (BDMV): An Active Reinduction Regimen for Children With Relapsed Acute Lymphoblastic Leukemia and Asparaginase Intolerance. J Pediatr Hematol Oncol. 2016 07; 38(5):345-9. Yeo KK, Gaynon PS, Fu CH, Wayne AS, Sun W. PMID: 27352191; PMCID: PMC7451259.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    27. Oligoclonality and new agent evaluation in acute lymphoblastic leukaemia. Br J Haematol. 2016 Jun; 173(6):950-7. Gaynon PS, Sun W. PMID: 27221005.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCellsPHPublic Health
    28. A Phase I Study of Quizartinib Combined with Chemotherapy in Relapsed Childhood Leukemia: A Therapeutic Advances in Childhood Leukemia & Lymphoma (TACL) Study. Clin Cancer Res. 2016 Aug 15; 22(16):4014-22. Cooper TM, Cassar J, Eckroth E, Malvar J, Sposto R, Gaynon P, Chang BH, Gore L, August K, Pollard JA, DuBois SG, Silverman LB, Oesterheld J, Gammon G, Magoon D, Annesley C, Brown PA. PMID: 26920889.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCTClinical Trials
    29. Reply: T-Cell Acute Lymphoblastic Leukemia, Minimal Residual Disease, and Lymphocyte Recovery. Pediatr Blood Cancer. 2016 May; 63(5):945. Parekh C, Gaynon PS, Abdel-Azim H. PMID: 26766623.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    30. Outcome of Children with Standard-Risk T-Lineage Acute Lymphoblastic Leukemia--Comparison among Different Treatment Strategies. Pediatr Blood Cancer. 2016 Feb; 63(2):255-61. Matloub Y, Stork L, Asselin B, Hunger SP, Borowitz M, Jones T, Bostrom B, Gastier-Foster JM, Heerema NA, Carroll A, Winick N, Carroll WL, Camitta B, Devidas M, Gaynon PS. PMID: 26485054; PMCID: PMC4715507.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    31. ALL and osteonecrosis. Blood. 2015 Oct 08; 126(15):1734-5. Gaynon PS. PMID: 26450951.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    32. Feasibility Study of a Novel Experimental Induction Protocol Combining B43-PAP (Anti-CD19) Immunotoxin With Standard Induction Chemotherapy in Children and Adolescents With Relapsed B-Lineage ALL: A Report From the Children's Oncology Group. J Immunother. 2015 Sep; 38(7):299-305. Meany HJ, Seibel NL, Krailo M, Villaluna D, Chen Z, Gaynon P, Neglia JP, Park JR, Hutchinson R, Sato JK, Wells RJ, Woods WG, Reaman G. PMID: 26261894; PMCID: PMC4536569.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCellsCTClinical Trials
    33. Allergic reactions and antiasparaginase antibodies in children with high-risk acute lymphoblastic leukemia: A children's oncology group report. Cancer. 2015 Dec 01; 121(23):4205-11. Ko RH, Jones TL, Radvinsky D, Robison N, Gaynon PS, Panosyan EH, Avramis IA, Avramis VI, Rubin J, Ettinger LJ, Seibel NL, Dhall G. PMID: 26308766; PMCID: PMC4795901.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    34. Comparative Toxicity by Sex Among Children Treated for Acute Lymphoblastic Leukemia: A Report From the Children's Oncology Group. Pediatr Blood Cancer. 2015 Dec; 62(12):2140-9. Meeske KA, Ji L, Freyer DR, Gaynon P, Ruccione K, Butturini A, Avramis VI, Siegel S, Matloub Y, Seibel NL, Sposto R. PMID: 26173904; PMCID: PMC4624005.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCTClinical Trials
    35. End of induction minimal residual disease alone is not a useful determinant for risk stratified therapy in pediatric T-cell acute lymphoblastic leukemia. Pediatr Blood Cancer. 2015 Nov; 62(11):2040-3. Parekh C, Gaynon PS, Abdel-Azim H. PMID: 25976383; PMCID: PMC4583337.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    36. Improving access to novel agents for childhood leukemia. Cancer. 2015 Jun 15; 121(12):1927-36. Sun W, Gaynon PS, Sposto R, Wayne AS. PMID: 25678105; PMCID: PMC4457598.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    37. Increased post-induction intensification improves outcome in children and adolescents with a markedly elevated white blood cell count (≥200 × 10(9) /l) with T cell acute lymphoblastic leukaemia but not B cell disease: a report from the Children's Oncology Group. Br J Haematol. 2015 Feb; 168(4):533-46. Hastings C, Gaynon PS, Nachman JB, Sather HN, Lu X, Devidas M, Seibel NL. PMID: 25308804; PMCID: PMC4314336.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    38. High-resolution melting curve analysis, a rapid and affordable method for mutation analysis in childhood acute myeloid leukemia. Front Pediatr. 2014; 2:96. Liu Y, Tang J, Wakamatsu P, Xue H, Chen J, Gaynon PS, Shen S, Sun W. PMID: 25250304; PMCID: PMC4158872.
      View in: PubMed   Mentions: 4  
    39. CD19-antigen specific nanoscale liposomal formulation of a SYK P-site inhibitor causes apoptotic destruction of human B-precursor leukemia cells. Integr Biol (Camb). 2014 Aug; 6(8):766-80. Myers DE, Yiv S, Qazi S, Ma H, Cely I, Shahidzadeh A, Arellano M, Finestone E, Gaynon PS, Termuhlen A, Cheng J, Uckun FM. PMID: 24910947; PMCID: PMC4158964.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    40. A phase I study of EZN-3042, a novel survivin messenger ribonucleic acid (mRNA) antagonist, administered in combination with chemotherapy in children with relapsed acute lymphoblastic leukemia (ALL): a report from the therapeutic advances in childhood leukemia and lymphoma (TACL) consortium. J Pediatr Hematol Oncol. 2014 Aug; 36(6):458-63. Raetz EA, Morrison D, Romanos-Sirakis E, Gaynon P, Sposto R, Bhojwani D, Bostrom BC, Brown P, Eckroth E, Cassar J, Malvar J, Buchbinder A, Carroll WL. PMID: 24276047; PMCID: PMC4238428.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCellsCTClinical Trials
    41. Impact on survival and toxicity by duration of weight extremes during treatment for pediatric acute lymphoblastic leukemia: A report from the Children's Oncology Group. J Clin Oncol. 2014 May 01; 32(13):1331-7. Orgel E, Sposto R, Malvar J, Seibel NL, Ladas E, Gaynon PS, Freyer DR. PMID: 24687836; PMCID: PMC3992723.
      View in: PubMed   Mentions: 59     Fields:    Translation:Humans
    42. Long-term follow-up of imatinib in pediatric Philadelphia chromosome-positive acute lymphoblastic leukemia: Children's Oncology Group study AALL0031. Leukemia. 2014 Jul; 28(7):1467-71. Schultz KR, Carroll A, Heerema NA, Bowman WP, Aledo A, Slayton WB, Sather H, Devidas M, Zheng HW, Davies SM, Gaynon PS, Trigg M, Rutledge R, Jorstad D, Winick N, Borowitz MJ, Hunger SP, Carroll WL, Camitta B, Children’s Oncology Group. PMID: 24441288; PMCID: PMC4282929.
      View in: PubMed   Mentions: 185     Fields:    Translation:Humans
    43. Philadelphia chromosome-negative very high-risk acute lymphoblastic leukemia in children and adolescents: results from Children's Oncology Group Study AALL0031. Leukemia. 2014 Apr; 28(4):964-7. Schultz KR, Devidas M, Bowman WP, Aledo A, Slayton WB, Sather H, Zheng HW, Davies SM, Gaynon PS, Trigg M, Rutledge R, Jorstad D, Carroll AJ, Heerema N, Winick N, Borowitz MJ, Hunger SP, Carroll WL, Camitta B, Children’s Oncology Group. PMID: 24434862; PMCID: PMC4283793.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    44. Recent advances in acute lymphoblastic leukemia in children and adolescents: an expert panel discussion. Curr Opin Oncol. 2013 Dec; 25 Suppl 3:S1-13; quiz S14-6. Asselin BL, Gaynon P, Whitlock JA. PMID: 24305505.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    45. Constitutive function of the Ikaros transcription factor in primary leukemia cells from pediatric newly diagnosed high-risk and relapsed B-precursor ALL patients. PLoS One. 2013; 8(11):e80732. Uckun FM, Ma H, Ishkhanian R, Arellano M, Shahidzadeh A, Termuhlen A, Gaynon PS, Qazi S. PMID: 24278314; PMCID: PMC3835424.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    46. Once upon a time--a personal view on episodes in leukemia research in Germany, and beyond. Klin Padiatr. 2013 May; 225 Suppl 1:S5. Gaynon P. PMID: 23700056.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    47. The principle and practice of reinduction therapy (in ALL): repetita iuvant! Klin Padiatr. 2013 May; 225 Suppl 1:S57-61. Masera G, Conter V, Gaynon PS. PMID: 23700058.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    48. Nanoscale liposomal formulation of a SYK P-site inhibitor against B-precursor leukemia. Blood. 2013 May 23; 121(21):4348-54. Uckun FM, Qazi S, Cely I, Sahin K, Shahidzadeh A, Ozercan I, Yin Q, Gaynon P, Termuhlen A, Cheng J, Yiv S. PMID: 23568490; PMCID: PMC3663427.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    49. Subcutaneous Panniculitis-like T-cell lymphoma in two pediatric patients: an HIV-positive adolescent and a 4-month-old infant. Fetal Pediatr Pathol. 2013 Jun; 32(3):175-83. Acree SC, Tovar JP, Pattengale PK, Wang LL, Church JA, Gaynon PS, Cassarino DS. PMID: 23092204.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    50. ABT-751 in relapsed childhood acute lymphoblastic leukemia. J Pediatr Hematol Oncol. 2012 Oct; 34(7):583-4. Gaynon PS, Harned TM, Therapeutic Advances in Childhood Leukemia/Lymphoma Consortium. PMID: 22584778.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    51. Effect of alternate-week versus continuous dexamethasone scheduling on the risk of osteonecrosis in paediatric patients with acute lymphoblastic leukaemia: results from the CCG-1961 randomised cohort trial. Lancet Oncol. 2012 Sep; 13(9):906-15. Mattano LA, Devidas M, Nachman JB, Sather HN, Hunger SP, Steinherz PG, Gaynon PS, Seibel NL, Children's Oncology Group. PMID: 22901620; PMCID: PMC3448283.
      View in: PubMed   Mentions: 69     Fields:    Translation:Humans
    52. Bortezomib with chemotherapy is highly active in advanced B-precursor acute lymphoblastic leukemia: Therapeutic Advances in Childhood Leukemia & Lymphoma (TACL) Study. Blood. 2012 Jul 12; 120(2):285-90. Messinger YH, Gaynon PS, Sposto R, van der Giessen J, Eckroth E, Malvar J, Bostrom BC, Therapeutic Advances in Childhood Leukemia & Lymphoma (TACL) Consortium. PMID: 22653976.
      View in: PubMed   Mentions: 101     Fields:    Translation:HumansCTClinical Trials
    53. Anaphylactic reaction to etoposide phosphate. Pediatr Blood Cancer. 2012 Oct; 59(4):765. Lindsay H, Gaynon P. PMID: 22522419.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    54. Outcomes after induction failure in childhood acute lymphoblastic leukemia. N Engl J Med. 2012 Apr 12; 366(15):1371-81. Schrappe M, Hunger SP, Pui CH, Saha V, Gaynon PS, Baruchel A, Conter V, Otten J, Ohara A, Versluys AB, Escherich G, Heyman M, Silverman LB, Horibe K, Mann G, Camitta BM, Harbott J, Riehm H, Richards S, Devidas M, Zimmermann M. PMID: 22494120; PMCID: PMC3374496.
      View in: PubMed   Mentions: 124     Fields:    Translation:Humans
    55. The role of cytotoxic therapy with hematopoietic stem cell transplantation in the treatment of pediatric acute lymphoblastic leukemia: update of the 2005 evidence-based review. ASBMT Position Statement. Biol Blood Marrow Transplant. 2012 Jul; 18(7):979-81. Oliansky DM, Camitta B, Gaynon P, Nieder ML, Parsons SK, Pulsipher MA, Dillon H, Ratko TA, Wall D, McCarthy PL, Hahn T. PMID: 22490784.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    56. Improved survival for children and adolescents with acute lymphoblastic leukemia between 1990 and 2005: a report from the children's oncology group. J Clin Oncol. 2012 May 10; 30(14):1663-9. Hunger SP, Lu X, Devidas M, Camitta BM, Gaynon PS, Winick NJ, Reaman GH, Carroll WL. PMID: 22412151; PMCID: PMC3383113.
      View in: PubMed   Mentions: 520     Fields:    Translation:Humans
    57. Role of cytotoxic therapy with hematopoietic stem cell transplantation in the treatment of pediatric acute lymphoblastic leukemia: update of the 2005 evidence-based review. Biol Blood Marrow Transplant. 2012 Apr; 18(4):505-22. Oliansky DM, Camitta B, Gaynon P, Nieder ML, Parsons SK, Pulsipher MA, Dillon H, Ratko TA, Wall D, McCarthy PL, Hahn T, American Society for Blood and Marrow Transplantation. PMID: 22209888.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    58. CD22 Exon 12 deletion is a characteristic genetic defect of therapy-refractory clones in paediatric acute lymphoblastic leukaemia. Br J Haematol. 2012 Jan; 156(1):89-98. Ma H, Qazi S, Ozer Z, Gaynon P, Reaman GH, Uckun FM. PMID: 22017452.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    59. Phase 2 trial of clofarabine in combination with etoposide and cyclophosphamide in pediatric patients with refractory or relapsed acute lymphoblastic leukemia. Blood. 2011 Dec 01; 118(23):6043-9. Hijiya N, Thomson B, Isakoff MS, Silverman LB, Steinherz PG, Borowitz MJ, Kadota R, Cooper T, Shen V, Dahl G, Thottassery JV, Jeha S, Maloney K, Paul JA, Barry E, Carroll WL, Gaynon PS. PMID: 21967976; PMCID: PMC3731655.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCTClinical Trials
    60. A remembrance: James B. Nachman 1948-2011. Pediatr Blood Cancer. 2011 Oct; 57(4):533-4. Gaynon PS. PMID: 21826779.
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    62. Escalating intravenous methotrexate improves event-free survival in children with standard-risk acute lymphoblastic leukemia: a report from the Children's Oncology Group. Blood. 2011 Jul 14; 118(2):243-51. Matloub Y, Bostrom BC, Hunger SP, Stork LC, Angiolillo A, Sather H, La M, Gastier-Foster JM, Heerema NA, Sailer S, Buckley PJ, Thomson B, Cole C, Nachman JB, Reaman G, Winick N, Carroll WL, Devidas M, Gaynon PS. PMID: 21562038; PMCID: PMC3138679.
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    63. Postrelapse survival in childhood acute lymphoblastic leukemia is independent of initial treatment intensity: a report from the Children's Oncology Group. Blood. 2011 Mar 17; 117(11):3010-5. Freyer DR, Devidas M, La M, Carroll WL, Gaynon PS, Hunger SP, Seibel NL. PMID: 21193696; PMCID: PMC3062307.
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    64. Outcome for children treated for relapsed or refractory acute myelogenous leukemia (rAML): a Therapeutic Advances in Childhood Leukemia (TACL) Consortium study. Pediatr Blood Cancer. 2010 Sep; 55(3):421-9. Gorman MF, Ji L, Ko RH, Barnette P, Bostrom B, Hutchinson R, Raetz E, Seibel NL, Twist CJ, Eckroth E, Sposto R, Gaynon PS, Loh ML. PMID: 20658611.
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    65. Phase I study of bortezomib combined with chemotherapy in children with relapsed childhood acute lymphoblastic leukemia (ALL): a report from the therapeutic advances in childhood leukemia (TACL) consortium. Pediatr Blood Cancer. 2010 Aug; 55(2):254-9. Messinger Y, Gaynon P, Raetz E, Hutchinson R, Dubois S, Glade-Bender J, Sposto R, van der Giessen J, Eckroth E, Bostrom BC. PMID: 20582937.
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    66. Toxicity assessment of molecularly targeted drugs incorporated into multiagent chemotherapy regimens for pediatric acute lymphocytic leukemia (ALL): review from an international consensus conference. Pediatr Blood Cancer. 2010 Jul 01; 54(7):872-8. Horton TM, Sposto R, Brown P, Reynolds CP, Hunger SP, Winick NJ, Raetz EA, Carroll WL, Arceci RJ, Borowitz MJ, Gaynon PS, Gore L, Jeha S, Maurer BJ, Siegel SE, Biondi A, Kearns PR, Narendran A, Silverman LB, Smith MA, Zwaan CM, Whitlock JA, ALLNA 2008 Conference. PMID: 20127846; PMCID: PMC2857540.
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    67. Population pharmacokinetics of clofarabine and its metabolite 6-ketoclofarabine in adult and pediatric patients with cancer. Cancer Chemother Pharmacol. 2011 Apr; 67(4):875-90. Bonate PL, Cunningham CC, Gaynon P, Jeha S, Kadota R, Lam GN, Razzouk B, Rytting M, Steinherz P, Weitman S. PMID: 20582417.
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    68. Oral 6-mercaptopurine versus oral 6-thioguanine and veno-occlusive disease in children with standard-risk acute lymphoblastic leukemia: report of the Children's Oncology Group CCG-1952 clinical trial. Blood. 2010 Apr 08; 115(14):2740-8. Stork LC, Matloub Y, Broxson E, La M, Yanofsky R, Sather H, Hutchinson R, Heerema NA, Sorrell AD, Masterson M, Bleyer A, Gaynon PS. PMID: 20124218; PMCID: PMC2854423.
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    69. Long-term results of the children's cancer group studies for childhood acute lymphoblastic leukemia 1983-2002: a Children's Oncology Group Report. Leukemia. 2010 Feb; 24(2):285-97. Gaynon PS, Angiolillo AL, Carroll WL, Nachman JB, Trigg ME, Sather HN, Hunger SP, Devidas M, Children's Oncology Group. PMID: 20016531; PMCID: PMC2906139.
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    70. Prospective monitoring for invasive aspergillosis using galactomannan and polymerase chain reaction in high risk pediatric patients. J Pediatr Hematol Oncol. 2009 Dec; 31(12):920-6. Armenian SH, Nash KA, Kapoor N, Franklin JL, Gaynon PS, Ross LA, Hoffman JA. PMID: 19855303.
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    71. Outcome of patients treated for relapsed or refractory acute lymphoblastic leukemia: a Therapeutic Advances in Childhood Leukemia Consortium study. J Clin Oncol. 2010 Feb 01; 28(4):648-54. Ko RH, Ji L, Barnette P, Bostrom B, Hutchinson R, Raetz E, Seibel NL, Twist CJ, Eckroth E, Sposto R, Gaynon PS, Loh ML. PMID: 19841326; PMCID: PMC2815999.
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    72. Improved early event-free survival with imatinib in Philadelphia chromosome-positive acute lymphoblastic leukemia: a children's oncology group study. J Clin Oncol. 2009 Nov 01; 27(31):5175-81. Schultz KR, Bowman WP, Aledo A, Slayton WB, Sather H, Devidas M, Wang C, Davies SM, Gaynon PS, Trigg M, Rutledge R, Burden L, Jorstad D, Carroll A, Heerema NA, Winick N, Borowitz MJ, Hunger SP, Carroll WL, Camitta B. PMID: 19805687; PMCID: PMC2773475.
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    73. Young adults with acute lymphoblastic leukemia have an excellent outcome with chemotherapy alone and benefit from intensive postinduction treatment: a report from the children's oncology group. J Clin Oncol. 2009 Nov 01; 27(31):5189-94. Nachman JB, La MK, Hunger SP, Heerema NA, Gaynon PS, Hastings C, Mattano LA, Sather H, Devidas M, Freyer DR, Steinherz PG, Seibel NL. PMID: 19805689; PMCID: PMC3053149.
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    74. An adjustment for patient heterogeneity in the design of two-stage phase II trials. Stat Med. 2009 Sep 10; 28(20):2566-79. Sposto R, Gaynon PS. PMID: 19521973.
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    75. A multi-center phase I study of clofarabine, etoposide and cyclophosphamide in combination in pediatric patients with refractory or relapsed acute leukemia. Leukemia. 2009 Dec; 23(12):2259-64. Hijiya N, Gaynon P, Barry E, Silverman L, Thomson B, Chu R, Cooper T, Kadota R, Rytting M, Steinherz P, Shen V, Jeha S, Abichandani R, Carroll WL. PMID: 19741725.
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    76. Phase II study of clofarabine in pediatric patients with refractory or relapsed acute myeloid leukemia. J Clin Oncol. 2009 Sep 10; 27(26):4392-7. Jeha S, Razzouk B, Rytting M, Rheingold S, Albano E, Kadota R, Luchtman-Jones L, Bomgaars L, Gaynon P, Goldman S, Ritchey K, Arceci R, Altman A, Stine K, Steinherz L, Steinherz P. PMID: 19652076; PMCID: PMC2744276.
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    77. Relapsed acute lymphoblastic leukemia: current status and future opportunities. Curr Oncol Rep. 2008 Nov; 10(6):453-8. Harned TM, Gaynon P. PMID: 18928659.
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    78. Factors influencing survival after relapse from acute lymphoblastic leukemia: a Children's Oncology Group study. Leukemia. 2008 Dec; 22(12):2142-50. Nguyen K, Devidas M, Cheng SC, La M, Raetz EA, Carroll WL, Winick NJ, Hunger SP, Gaynon PS, Loh ML, Children's Oncology Group. PMID: 18818707; PMCID: PMC2872117.
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    79. Reinduction platform for children with first marrow relapse of acute lymphoblastic Leukemia: A Children's Oncology Group Study[corrected]. J Clin Oncol. 2008 Aug 20; 26(24):3971-8. Raetz EA, Borowitz MJ, Devidas M, Linda SB, Hunger SP, Winick NJ, Camitta BM, Gaynon PS, Carroll WL. PMID: 18711187; PMCID: PMC2654313.
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    80. Ten-year survival of children with acute lymphoblastic leukemia: a report from the Children's Oncology Group. Leuk Lymphoma. 2008 Jun; 49(6):1142-54. Trigg ME, Sather HN, Reaman GH, Tubergen DG, Steinherz PG, Gaynon PS, Uckun FM, Hammond GD, Children's Oncology Group. PMID: 18569638.
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    81. What determines the outcomes for adolescents and young adults with acute lymphoblastic leukemia treated on cooperative group protocols? A comparison of Children's Cancer Group and Cancer and Leukemia Group B studies. Blood. 2008 Sep 01; 112(5):1646-54. Stock W, La M, Sanford B, Bloomfield CD, Vardiman JW, Gaynon P, Larson RA, Nachman J, Children's Cancer Group, Cancer and Leukemia Group B studies. PMID: 18502832; PMCID: PMC2518876.
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    82. Treating refractory leukemias in childhood, role of clofarabine. Ther Clin Risk Manag. 2008 Apr; 4(2):327-36. Harned TM, Gaynon PS. PMID: 18728851; PMCID: PMC2504075.
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    83. Outcome after relapse among children with standard-risk acute lymphoblastic leukemia: Children's Oncology Group study CCG-1952. J Clin Oncol. 2007 Dec 20; 25(36):5800-7. Malempati S, Gaynon PS, Sather H, La MK, Stork LC, Children's Oncology Group. PMID: 18089878.
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    84. Early postinduction intensification therapy improves survival for children and adolescents with high-risk acute lymphoblastic leukemia: a report from the Children's Oncology Group. Blood. 2008 Mar 01; 111(5):2548-55. Seibel NL, Steinherz PG, Sather HN, Nachman JB, Delaat C, Ettinger LJ, Freyer DR, Mattano LA, Hastings CA, Rubin CM, Bertolone K, Franklin JL, Heerema NA, Mitchell TL, Pyesmany AF, La MK, Edens C, Gaynon PS. PMID: 18039957; PMCID: PMC2254538.
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    85. Specific extra chromosomes occur in a modal number dependent pattern in pediatric acute lymphoblastic leukemia. Genes Chromosomes Cancer. 2007 Jul; 46(7):684-93. Heerema NA, Raimondi SC, Anderson JR, Biegel J, Camitta BM, Cooley LD, Gaynon PS, Hirsch B, Magenis RE, McGavran L, Patil S, Pettenati MJ, Pullen J, Rao K, Roulston D, Schneider NR, Shuster JJ, Sanger W, Sutcliffe MJ, van Tuinen P, Watson MS, Carroll AJ. PMID: 17431878.
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    86. Treatment of pediatric acute lymphoblastic leukemia: progress achieved and challenges remaining. Curr Hematol Malig Rep. 2007 Jul; 2(3):193-201. Gaynon PS. PMID: 20425369.
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    87. Obesity and outcome in pediatric acute lymphoblastic leukemia. J Clin Oncol. 2007 May 20; 25(15):2063-9. Butturini AM, Dorey FJ, Lange BJ, Henry DW, Gaynon PS, Fu C, Franklin J, Siegel SE, Seibel NL, Rogers PC, Sather H, Trigg M, Bleyer WA, Carroll WL. PMID: 17513811.
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    88. Risk- and response-based classification of childhood B-precursor acute lymphoblastic leukemia: a combined analysis of prognostic markers from the Pediatric Oncology Group (POG) and Children's Cancer Group (CCG). Blood. 2007 Feb 01; 109(3):926-35. Schultz KR, Pullen DJ, Sather HN, Shuster JJ, Devidas M, Borowitz MJ, Carroll AJ, Heerema NA, Rubnitz JE, Loh ML, Raetz EA, Winick NJ, Hunger SP, Carroll WL, Gaynon PS, Camitta BM. PMID: 17003380; PMCID: PMC1785141.
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    89. Asparagine depletion after pegylated E. coli asparaginase treatment and induction outcome in children with acute lymphoblastic leukemia in first bone marrow relapse: a Children's Oncology Group study (CCG-1941). Pediatr Blood Cancer. 2006 Aug; 47(2):141-6. Jarrar M, Gaynon PS, Periclou AP, Fu C, Harris RE, Stram D, Altman A, Bostrom B, Breneman J, Steele D, Trigg M, Zipf T, Avramis VI. PMID: 16425271.
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    90. Bone marrow transplantation versus prolonged intensive chemotherapy for children with acute lymphoblastic leukemia and an initial bone marrow relapse within 12 months of the completion of primary therapy: Children's Oncology Group study CCG-1941. J Clin Oncol. 2006 Jul 01; 24(19):3150-6. Gaynon PS, Harris RE, Altman AJ, Bostrom BC, Breneman JC, Hawks R, Steele D, Zipf T, Stram DO, Villaluna D, Trigg ME. PMID: 16717292.
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    91. Phase II study of clofarabine in pediatric patients with refractory or relapsed acute lymphoblastic leukemia. J Clin Oncol. 2006 Apr 20; 24(12):1917-23. Jeha S, Gaynon PS, Razzouk BI, Franklin J, Kadota R, Shen V, Luchtman-Jones L, Rytting M, Bomgaars LR, Rheingold S, Ritchey K, Albano E, Arceci RJ, Goldman S, Griffin T, Altman A, Gordon B, Steinherz L, Weitman S, Steinherz P. PMID: 16622268.
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    92. Intrathecal triple therapy decreases central nervous system relapse but fails to improve event-free survival when compared with intrathecal methotrexate: results of the Children's Cancer Group (CCG) 1952 study for standard-risk acute lymphoblastic leukemia, reported by the Children's Oncology Group. Blood. 2006 Aug 15; 108(4):1165-73. Matloub Y, Lindemulder S, Gaynon PS, Sather H, La M, Broxson E, Yanofsky R, Hutchinson R, Heerema NA, Nachman J, Blake M, Wells LM, Sorrell AD, Masterson M, Kelleher JF, Stork LC, Children's Oncology Group. PMID: 16609069; PMCID: PMC1895867.
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    93. Treatment adherence and 6-mercaptopurine metabolites. Pediatr Blood Cancer. 2006 Feb; 46(2):120-1. Gaynon PS. PMID: 16200555.
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    94. The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of acute lymphoblastic leukemia in adults: an evidence-based review. Biol Blood Marrow Transplant. 2006 Jan; 12(1):1-30. Hahn T, Wall D, Camitta B, Davies S, Dillon H, Gaynon P, Larson RA, Parsons S, Seidenfeld J, Weisdorf D, McCarthy PL. PMID: 16399566.
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    95. Childhood acute lymphoblastic leukaemia and relapse. Br J Haematol. 2005 Dec; 131(5):579-87. Gaynon PS. PMID: 16351633.
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    96. The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of acute lymphoblastic leukemia in children: an evidence-based review. Biol Blood Marrow Transplant. 2005 Nov; 11(11):823-61. Hahn T, Wall D, Camitta B, Davies S, Dillon H, Gaynon P, Larson RA, Parsons S, Seidenfeld J, Weisdorf D, McCarthy PL. PMID: 16275588.
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    97. Clinical characteristics and outcome of children with Down syndrome and acute lymphoblastic leukemia: a Children's Cancer Group study. Blood. 2005 Dec 15; 106(13):4043-9. Whitlock JA, Sather HN, Gaynon P, Robison LL, Wells RJ, Trigg M, Heerema NA, Bhatia S. PMID: 16109782.
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    98. The seventh international childhood acute lymphoblastic leukemia workshop report: Palermo, Italy, January 29--30, 2005. Leukemia. 2005 Jul; 19(7):1145-52. Aricó M, Baruchel A, Bertrand Y, Biondi A, Conter V, Eden T, Gadner H, Gaynon P, Horibe K, Hunger SP, Janka-Schaub G, Masera G, Nachman J, Pieters R, Schrappe M, Schmiegelow K, Valsecchi MG, Pui CH. PMID: 15902295.
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    99. Phase II study of nelarabine (compound 506U78) in children and young adults with refractory T-cell malignancies: a report from the Children's Oncology Group. J Clin Oncol. 2005 May 20; 23(15):3376-82. Berg SL, Blaney SM, Devidas M, Lampkin TA, Murgo A, Bernstein M, Billett A, Kurtzberg J, Reaman G, Gaynon P, Whitlock J, Krailo M, Harris MB, Children's Oncology Group. PMID: 15908649.
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    100. High concordance from independent studies by the Children's Cancer Group (CCG) and Pediatric Oncology Group (POG) associating favorable prognosis with combined trisomies 4, 10, and 17 in children with NCI Standard-Risk B-precursor Acute Lymphoblastic Leukemia: a Children's Oncology Group (COG) initiative. Leukemia. 2005 May; 19(5):734-40. Sutcliffe MJ, Shuster JJ, Sather HN, Camitta BM, Pullen J, Schultz KR, Borowitz MJ, Gaynon PS, Carroll AJ, Heerema NA. PMID: 15789069.
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    101. No prognostic effect of additional chromosomal abnormalities in children with acute lymphoblastic leukemia and 11q23 abnormalities. Leukemia. 2005 Apr; 19(4):557-63. Moorman AV, Raimondi SC, Pui CH, Baruchel A, Biondi A, Carroll AJ, Forestier E, Gaynon PS, Harbott J, Harms DO, Heerema N, Pieters R, Schrappe M, Silverman LB, Vilmer E, Harrison CJ, Ponte di Legno Working Group. PMID: 15744345.
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    102. Statement by members of the Ponte di Legno group on the right of children with leukemia to have full access to essential treatment for acute lymphoblastic leukemia. Ann Oncol. 2005 Jan; 16(1):169-70. Tognoni G, Masera G, Pui CH, Eden T, Nachman J, Gadner H, Gaynon PS, Evans WE, Schrappe M. PMID: 15598956.
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    103. Lymphoblast biology and outcome among children with Down syndrome and ALL treated on CCG-1952. Pediatr Blood Cancer. 2005 Jan; 44(1):21-8. Bassal M, La MK, Whitlock JA, Sather HN, Heerema NA, Gaynon PS, Stork LC. PMID: 15368546.
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    104. Population pharmacokinetics of clofarabine, a second-generation nucleoside analog, in pediatric patients with acute leukemia. J Clin Pharmacol. 2004 Nov; 44(11):1309-22. Bonate PL, Craig A, Gaynon P, Gandhi V, Jeha S, Kadota R, Lam GN, Plunkett W, Razzouk B, Rytting M, Steinherz P, Weitman S. PMID: 15496649.
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    105. Statement by members of the Ponte di Legno Group on the right of children to have full access to essential treatment for acute lymphoblastic leukemia. Pediatr Blood Cancer. 2004 Aug; 43(2):103-4. Masera G, Eden T, Schrappe M, Nachman J, Gadner H, Gaynon P, Evans WE, Pui CH, Ponte di Legno Group. PMID: 15236273.
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    106. Ponte di Legno Working Group: statement on the right of children with leukemia to have full access to essential treatment and report on the Sixth International Childhood Acute Lymphoblastic Leukemia Workshop. Leukemia. 2004 Jun; 18(6):1043-53. Pui CH, Schrappe M, Masera G, Nachman J, Gadner H, Eden OB, Evans WE, Gaynon P, Ponte di Legno Working Group. PMID: 15085155.
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    107. Deletion of 7p or monosomy 7 in pediatric acute lymphoblastic leukemia is an adverse prognostic factor: a report from the Children's Cancer Group. Leukemia. 2004 May; 18(5):939-47. Heerema NA, Nachman JB, Sather HN, La MK, Hutchinson R, Lange BJ, Bostrom B, Steinherz PG, Gaynon PS, Uckun FM, Children's Cancer Group. PMID: 14999294.
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    108. Asparaginase antibody and asparaginase activity in children with higher-risk acute lymphoblastic leukemia: Children's Cancer Group Study CCG-1961. J Pediatr Hematol Oncol. 2004 Apr; 26(4):217-26. Panosyan EH, Seibel NL, Martin-Aragon S, Gaynon PS, Avramis IA, Sather H, Franklin J, Nachman J, Ettinger LJ, La M, Steinherz P, Cohen LJ, Siegel SE, Avramis VI, Children's Cancer Group Study CCG-1961. PMID: 15087948.
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    109. Secondary cytogenetic aberrations in childhood Philadelphia chromosome positive acute lymphoblastic leukemia are nonrandom and may be associated with outcome. Leukemia. 2004 Apr; 18(4):693-702. Heerema NA, Harbott J, Galimberti S, Camitta BM, Gaynon PS, Janka-Schaub G, Kamps W, Basso G, Pui CH, Schrappe M, Auclerc MF, Carroll AJ, Conter V, Harrison CJ, Pullen J, Raimondi SC, Richards S, Riehm H, Sather HN, Shuster JJ, Silverman LB, Valsecchi MG, Aricò M, Acute Lymphoblastic Leukemia Study Groups, ALL-BFM, CoALL, AIEOP, DCLSG, FRALLE, CCG, DFCI, POG, St Jude, UKALL. PMID: 15044926.
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    110. RAS oncogene mutations and outcome of therapy for childhood acute lymphoblastic leukemia. Leukemia. 2004 Apr; 18(4):685-92. Perentesis JP, Bhatia S, Boyle E, Shao Y, Shu XO, Steinbuch M, Sather HN, Gaynon P, Kiffmeyer W, Envall-Fox J, Robison LL. PMID: 14990973.
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    111. Deamination of glutamine is a prerequisite for optimal asparagine deamination by asparaginases in vivo (CCG-1961). Anticancer Res. 2004 Mar-Apr; 24(2C):1121-5. Panosyan EH, Grigoryan RS, Avramis IA, Seibel NL, Gaynon PS, Siegel SE, Fingert HJ, Avramis VI. PMID: 15154634.
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    112. Changes of amino acid serum levels in pediatric patients with higher-risk acute lymphoblastic leukemia (CCG-1961). In Vivo. 2004 Mar-Apr; 18(2):107-12. Grigoryan RS, Panosyan EH, Seibel NL, Gaynon PS, Avramis IA, Avramis VI. PMID: 15113036.
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    113. Altered patterns of T cell cytokine production induced by relapsed pre-B ALL cells. Leuk Res. 2003 Dec; 27(12):1135-42. Reid GS, Terrett L, Alessandri AJ, Grubb S, Stork L, Seibel N, Gaynon P, Schultz KR. PMID: 12921952.
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    114. Reduced folate carrier and dihydrofolate reductase expression in acute lymphocytic leukemia may predict outcome: a Children's Cancer Group Study. J Pediatr Hematol Oncol. 2003 Sep; 25(9):688-95. Levy AS, Sather HN, Steinherz PG, Sowers R, La M, Moscow JA, Gaynon PS, Uckun FM, Bertino JR, Gorlick R, Children's Cancer Group Study. PMID: 12972803.
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    115. Preponderant mitotic activity of nonleukemic cells plays an important role in failures to detect abnormal clone in childhood acute lymphoblastic leukemia. J Pediatr Hematol Oncol. 2003 Jul; 25(7):520-5. Wu SQ, Weinberg KI, Joo WJ, Quinn JJ, Franklin J, Siegel SE, Gaynon PS. PMID: 12847317.
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    116. CNS-directed therapy for childhood acute lymphoblastic leukemia: Childhood ALL Collaborative Group overview of 43 randomized trials. J Clin Oncol. 2003 May 01; 21(9):1798-809. Clarke M, Gaynon P, Hann I, Harrison G, Masera G, Peto R, Richards S, Childhood ALL Collaborative Group. PMID: 12721257.
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    117. Intensification of therapy for children with lower-risk acute lymphoblastic leukemia: long-term follow-up of patients treated on Children's Cancer Group Trial 1881. J Clin Oncol. 2003 May 01; 21(9):1790-7. Hutchinson RJ, Gaynon PS, Sather H, Bertolone SJ, Cooper HA, Tannous R, Wells LM, Heerema NA, Sailer S, Trigg ME, Children's Cancer Group/Children's Oncology Group. PMID: 12721256.
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    118. Clinical heterogeneity in childhood acute lymphoblastic leukemia with 11q23 rearrangements. Leukemia. 2003 Apr; 17(4):700-6. Pui CH, Chessells JM, Camitta B, Baruchel A, Biondi A, Boyett JM, Carroll A, Eden OB, Evans WE, Gadner H, Harbott J, Harms DO, Harrison CJ, Harrison PL, Heerema N, Janka-Schaub G, Kamps W, Masera G, Pullen J, Raimondi SC, Richards S, Riehm H, Sallan S, Sather H, Shuster J, Silverman LB, Valsecchi MG, Vilmer E, Zhou Y, Gaynon PS, Schrappe M. PMID: 12682627.
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    119. Dexamethasone versus prednisone and daily oral versus weekly intravenous mercaptopurine for patients with standard-risk acute lymphoblastic leukemia: a report from the Children's Cancer Group. Blood. 2003 May 15; 101(10):3809-17. Bostrom BC, Sensel MR, Sather HN, Gaynon PS, La MK, Johnston K, Erdmann GR, Gold S, Heerema NA, Hutchinson RJ, Provisor AJ, Trigg ME, Children's Cancer Group. PMID: 12531809.
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    120. Racial and ethnic differences in survival of children with acute lymphoblastic leukemia. Blood. 2002 Sep 15; 100(6):1957-64. Bhatia S, Sather HN, Heerema NA, Trigg ME, Gaynon PS, Robison LL. PMID: 12200352.
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    121. Response to Donadieu and Hill "Clinical trials in childhood acute lymphoblastic leukemia: a common prognostic classification and a common induction therapy are now warranted". J Pediatr Hematol Oncol. 2002 Aug-Sep; 24(6):426-8. Gaynon PS. PMID: 12218587.
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    122. Glutathione S-transferase genotypes, genetic susceptibility, and outcome of therapy in childhood acute lymphoblastic leukemia. Blood. 2002 Jul 01; 100(1):67-71. Davies SM, Bhatia S, Ross JA, Kiffmeyer WR, Gaynon PS, Radloff GA, Robison LL, Perentesis JP. PMID: 12070010.
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    123. Low incidence of second neoplasms among children diagnosed with acute lymphoblastic leukemia after 1983. Blood. 2002 Jun 15; 99(12):4257-64. Bhatia S, Sather HN, Pabustan OB, Trigg ME, Gaynon PS, Robison LL. PMID: 12036851.
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    124. Outcome of treatment in childhood acute lymphoblastic leukaemia with rearrangements of the 11q23 chromosomal region. Lancet. 2002 Jun 01; 359(9321):1909-15. Pui CH, Gaynon PS, Boyett JM, Chessells JM, Baruchel A, Kamps W, Silverman LB, Biondi A, Harms DO, Vilmer E, Schrappe M, Camitta B. PMID: 12057554.
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    125. A randomized comparison of native Escherichia coli asparaginase and polyethylene glycol conjugated asparaginase for treatment of children with newly diagnosed standard-risk acute lymphoblastic leukemia: a Children's Cancer Group study. Blood. 2002 Mar 15; 99(6):1986-94. Avramis VI, Sencer S, Periclou AP, Sather H, Bostrom BC, Cohen LJ, Ettinger AG, Ettinger LJ, Franklin J, Gaynon PS, Hilden JM, Lange B, Majlessipour F, Mathew P, Needle M, Neglia J, Reaman G, Holcenberg JS, Stork L. PMID: 11877270.
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    126. A pharmacoeconomic analysis of pegaspargase versus native Escherichia coli L-asparaginase for the treatment of children with standard-risk, acute lymphoblastic leukemia: the Children's Cancer Group study (CCG-1962). J Pediatr Hematol Oncol. 2002 Mar-Apr; 24(3):175-81. Kurre HA, Ettinger AG, Veenstra DL, Gaynon PS, Franklin J, Sencer SF, Reaman GH, Lange BJ, Holcenberg JS. PMID: 11990302.
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    127. From where do clinical trials come? J Pediatr Hematol Oncol. 2002 Mar-Apr; 24(3):172-4. Gaynon PS. PMID: 11990301.
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    128. Abnormalities of chromosome bands 15q13-15 in childhood acute lymphoblastic leukemia. Cancer. 2002 Feb 15; 94(4):1102-10. Heerema NA, Sather HN, Sensel MG, La MK, Hutchinson RJ, Nachman JB, Reaman GH, Lange BJ, Steinherz PG, Bostrom BC, Gaynon PS, Uckun FM. PMID: 11920481.
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    129. Expression of TEL-AML1 fusion transcripts and response to induction therapy in standard risk acute lymphoblastic leukemia. Leuk Lymphoma. 2001 Jun; 42(1-2):41-56. Uckun FM, Pallisgaard N, Hokland P, Navara C, Narla R, Gaynon PS, Sather H, Heerema N. PMID: 11699220.
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    130. Duration of hospitalization as a measure of cost on Children's Cancer Group acute lymphoblastic leukemia studies. J Clin Oncol. 2001 Apr 01; 19(7):1916-25. Gaynon PS, Bostrom BC, Hutchinson RJ, Lange BJ, Nachman JB, Steinherz PG, Sensel MG, Lee MK, Stram DO, Sather HN. PMID: 11283123.
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    131. Bone marrow leukemic progenitor cell content in pediatric T-lineage acute lymphoblastic leukemia patients with an isolated extramedullary first relapse. Leuk Lymphoma. 2001 Jan; 40(3-4):279-85. Uckun FM, Gaynon PS, Stram DO, Sensel MG, Sarquis MB, Willoughby M. PMID: 11426549.
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    132. Long-term results of large prospective trials in childhood acute lymphoblastic leukemia. Leukemia. 2000 Dec; 14(12):2193-4. Schrappe M, Camitta B, Pui CH, Eden T, Gaynon P, Gustafsson G, Janka-Schaub GE, Kamps W, Masera G, Sallan S, Tsuchida M, Vilmer E. PMID: 11187910.
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    133. Children's Cancer Group trials in childhood acute lymphoblastic leukemia: 1983-1995. Leukemia. 2000 Dec; 14(12):2223-33. Gaynon PS, Trigg ME, Heerema NA, Sensel MG, Sather HN, Hammond GD, Bleyer WA. PMID: 11187913.
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    134. Abnormalities of chromosome bands 13q12 to 13q14 in childhood acute lymphoblastic leukemia. J Clin Oncol. 2000 Nov 15; 18(22):3837-44. Heerema NA, Sather HN, Sensel MG, Lee MK, Hutchinson RJ, Nachman JB, Reaman GH, Lange BJ, Steinherz PG, Bostrom BC, Gaynon PS, Uckun FM. PMID: 11078497.
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    135. Prognostic factors in acute lymphoblastic leukemia. J Pediatr Hematol Oncol. 2000 Sep-Oct; 22(5):403-4. Gaynon PS. PMID: 11037849.
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    136. Residual bone marrow leukemic progenitor cell burden after induction chemotherapy in pediatric patients with acute lymphoblastic leukemia. Clin Cancer Res. 2000 Aug; 6(8):3123-30. Uckun FM, Stork L, Seibel N, Sarquis M, Bedros C, Sather H, Sensel M, Reaman GH, Gaynon PS. PMID: 10955793.
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    137. Prognostic impact of trisomies of chromosomes 10, 17, and 5 among children with acute lymphoblastic leukemia and high hyperdiploidy (> 50 chromosomes). J Clin Oncol. 2000 May; 18(9):1876-87. Heerema NA, Sather HN, Sensel MG, Zhang T, Hutchinson RJ, Nachman JB, Lange BJ, Steinherz PG, Bostrom BC, Reaman GH, Gaynon PS, Uckun FM. PMID: 10784628.
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    138. Prognostic significance of cytogenetic abnormalities of chromosome arm 12p in childhood acute lymphoblastic leukemia: a report from the Children's Cancer Group. Cancer. 2000 Apr 15; 88(8):1945-54. Heerema NA, Sather HN, Sensel MG, Lee MK, Hutchinson R, Nachman JB, Lange BJ, Steinherz PG, Bostrom B, Gaynon PS, Uckun FM. PMID: 10760773.
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    139. Outcome of treatment in children with Philadelphia chromosome-positive acute lymphoblastic leukemia. N Engl J Med. 2000 Apr 06; 342(14):998-1006. Aricò M, Valsecchi MG, Camitta B, Schrappe M, Chessells J, Baruchel A, Gaynon P, Silverman L, Janka-Schaub G, Kamps W, Pui CH, Masera G. PMID: 10749961.
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    140. Clinical significance of deletions of chromosome arm 6q in childhood acute lymphoblastic leukemia: a report from the Children's Cancer Group. Leuk Lymphoma. 2000 Feb; 36(5-6):467-78. Heerema NA, Sather HN, Sensel MG, Lee MK, Hutchinson R, Lange BJ, Bostrom BC, Nachman JB, Steinherz PG, Gaynon PS, Uckun FM. PMID: 10784391.
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    141. Early testicular biopsy in males with acute lymphoblastic leukemia: lack of impact on subsequent event-free survival. J Pediatr Hematol Oncol. 2000 Jan-Feb; 22(1):27-33. Trigg ME, Steinherz PG, Chappell R, Johnstone HS, Gaynon PS, Kersey JH, Cherlow JM, Grossman NJ, Sather HN, Hammond GD. PMID: 10695818.
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    142. Hypodiploidy with less than 45 chromosomes confers adverse risk in childhood acute lymphoblastic leukemia: a report from the children's cancer group. Blood. 1999 Dec 15; 94(12):4036-45. Heerema NA, Nachman JB, Sather HN, Sensel MG, Lee MK, Hutchinson R, Lange BJ, Steinherz PG, Bostrom B, Gaynon PS, Uckun F. PMID: 10590047.
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    143. Expression of aberrantly spliced oncogenic ikaros isoforms in childhood acute lymphoblastic leukemia. J Clin Oncol. 1999 Dec; 17(12):3753-66. Sun L, Goodman PA, Wood CM, Crotty ML, Sensel M, Sather H, Navara C, Nachman J, Steinherz PG, Gaynon PS, Seibel N, Vassilev A, Juran BD, Reaman GH, Uckun FM. PMID: 10577847.
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    144. Association of chromosome arm 9p abnormalities with adverse risk in childhood acute lymphoblastic leukemia: A report from the Children's Cancer Group. Blood. 1999 Sep 01; 94(5):1537-44. Heerema NA, Sather HN, Sensel MG, Liu-Mares W, Lange BJ, Bostrom BC, Nachman JB, Steinherz PG, Hutchinson R, Gaynon PS, Arthur DC, Uckun FM. PMID: 10477677.
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    145. Paucity of leukemic progenitor cells in the bone marrow of pediatric B-lineage acute lymphoblastic leukemia patients with an isolated extramedullary first relapse. Clin Cancer Res. 1999 Sep; 5(9):2415-20. Uckun FM, Gaynon PS, Stram DO, Sensel MG, Sarquis MB, Lazarus KH, Willoughby M. PMID: 10499612.
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    146. Expression of dominant-negative Ikaros isoforms in T-cell acute lymphoblastic leukemia. Clin Cancer Res. 1999 Aug; 5(8):2112-20. Sun L, Crotty ML, Sensel M, Sather H, Navara C, Nachman J, Steinherz PG, Gaynon PS, Seibel N, Mao C, Vassilev A, Reaman GH, Uckun FM. PMID: 10473095.
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    147. Poor treatment outcome of Philadelphia chromosome-positive pediatric acute lymphoblastic leukemia despite intensive chemotherapy. Leuk Lymphoma. 1999 Mar; 33(1-2):101-6. Uckun FM, Nachman JB, Sather HN, Sensel MG, Kraft P, Steinherz PG, Lange B, Hutchinson R, Reaman GH, Gaynon PS, Heerema NA. PMID: 10194126.
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    148. Treatment outcome and prognostic factors for infants with acute lymphoblastic leukemia treated on two consecutive trials of the Children's Cancer Group. J Clin Oncol. 1999 Feb; 17(2):445-55. Reaman GH, Sposto R, Sensel MG, Lange BJ, Feusner JH, Heerema NA, Leonard M, Holmes EJ, Sather HN, Pendergrass TW, Johnstone HS, O'Brien RT, Steinherz PG, Zeltzer PM, Gaynon PS, Trigg ME, Uckun FM. PMID: 10080584.
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    149. Prognostic significance of T-lineage leukemic cell growth in SCID mice: a Children's Cancer Group study. Leuk Lymphoma. 1999 Feb; 32(5-6):475-87. Uckun FM, Waurzyniak BJ, Sather HN, Sensel MG, Chelstrom L, Nachman J, Gaynon PS, Bostrom B, Ek O, Sarquis M, Steinherz PG, Reaman GH. PMID: 10048420.
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    150. Glucocorticosteroid therapy in childhood acute lymphoblastic leukemia. Adv Exp Med Biol. 1999; 457:593-605. Gaynon PS, Carrel AL. PMID: 10500839.
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    151. Low-dose cyclosporin A therapy in children with refractory immune thrombocytopenic purpura. J Pediatr Hematol Oncol. 1999 Jan-Feb; 21(1):77-9. Moskowitz IP, Gaynon PS, Shahidi NT, Cripe TP. PMID: 10029820.
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    152. Distinct in vivo engraftment and growth patterns of t(1;19)+/E2A-PBX1+ and t(9;22)+/BCR-ABL+ human leukemia cells in SCID mice. Leuk Lymphoma. 1998 Dec; 32(1-2):77-87. Waurzyniak BJ, Heerema N, Sensel MG, Gaynon PS, Kraft P, Sather HN, Chelstrom L, Reaman GH, Uckun FM. PMID: 10037003.
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    153. Clinical significance of Philadelphia chromosome positive pediatric acute lymphoblastic leukemia in the context of contemporary intensive therapies: a report from the Children's Cancer Group. Cancer. 1998 Nov 01; 83(9):2030-9. Uckun FM, Nachman JB, Sather HN, Sensel MG, Kraft P, Steinherz PG, Lange B, Hutchinson R, Reaman GH, Gaynon PS, Heerema NA. PMID: 9806664.
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    154. Treatment of human B-cell precursor leukemia in SCID mice by using a combination of the anti-CD19 immunotoxin B43-PAP with the standard chemotherapeutic drugs vincristine, methylprednisolone, and L-asparaginase. Leuk Lymphoma. 1998 Sep; 31(1-2):143-9. Ek O, Gaynon P, Zeren T, Chelstrom LM, Myers DE, Uckun FM. PMID: 9720724.
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    155. Prognostic significance of B-lineage leukemic cell growth in SCID mice: a Children's Cancer Group Study. Leuk Lymphoma. 1998 Aug; 30(5-6):503-14. Uckun FM, Sather HN, Waurzyniak BJ, Sensel MG, Chelstrom L, Ek O, Sarquis MB, Nachman J, Bostrom B, Reaman GH, Gaynon PS. PMID: 9711913.
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    156. Clinical significance of MLL-AF4 fusion transcript expression in the absence of a cytogenetically detectable t(4;11)(q21;q23) chromosomal translocation. Blood. 1998 Aug 01; 92(3):810-21. Uckun FM, Herman-Hatten K, Crotty ML, Sensel MG, Sather HN, Tuel-Ahlgren L, Sarquis MB, Bostrom B, Nachman JB, Steinherz PG, Gaynon PS, Heerema N. PMID: 9680349.
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    157. Primary blasts from infants with acute lymphoblastic leukemia cause overt leukemia in SCID mice. Leuk Lymphoma. 1998 Jul; 30(3-4):269-77. Uckun FM, Waurzyniak BJ, Sensel MG, Chelstrom L, Crotty ML, Gaynon PS, Reaman GH. PMID: 9713959.
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    158. Augmented post-induction therapy for children with high-risk acute lymphoblastic leukemia and a slow response to initial therapy. N Engl J Med. 1998 Jun 04; 338(23):1663-71. Nachman JB, Sather HN, Sensel MG, Trigg ME, Cherlow JM, Lukens JN, Wolff L, Uckun FM, Gaynon PS. PMID: 9614257.
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    159. Frequency and clinical significance of cytogenetic abnormalities in pediatric T-lineage acute lymphoblastic leukemia: a report from the Children's Cancer Group. J Clin Oncol. 1998 Apr; 16(4):1270-8. Heerema NA, Sather HN, Sensel MG, Kraft P, Nachman JB, Steinherz PG, Lange BJ, Hutchinson RS, Reaman GH, Trigg ME, Arthur DC, Gaynon PS, Uckun FM. PMID: 9552025.
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    160. Survival after relapse in childhood acute lymphoblastic leukemia: impact of site and time to first relapse--the Children's Cancer Group Experience. Cancer. 1998 Apr 01; 82(7):1387-95. Gaynon PS, Qu RP, Chappell RJ, Willoughby ML, Tubergen DG, Steinherz PG, Trigg ME. PMID: 9529033.
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    161. Response of children with high-risk acute lymphoblastic leukemia treated with and without cranial irradiation: a report from the Children's Cancer Group. J Clin Oncol. 1998 Mar; 16(3):920-30. Nachman J, Sather HN, Cherlow JM, Sensel MG, Gaynon PS, Lukens JN, Wolff L, Trigg ME. PMID: 9508174.
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    162. Clinical significance of translocation t(1;19) in childhood acute lymphoblastic leukemia in the context of contemporary therapies: a report from the Children's Cancer Group. J Clin Oncol. 1998 Feb; 16(2):527-35. Uckun FM, Sensel MG, Sather HN, Gaynon PS, Arthur DC, Lange BJ, Steinherz PG, Kraft P, Hutchinson R, Nachman JB, Reaman GH, Heerema NA. PMID: 9469337.
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    163. Treatment of patients with acute lymphoblastic leukemia with bulky extramedullary disease and T-cell phenotype or other poor prognostic features: randomized controlled trial from the Children's Cancer Group. Cancer. 1998 Feb 01; 82(3):600-12. Steinherz PG, Gaynon PS, Breneman JC, Cherlow JM, Grossman NJ, Kersey JH, Johnstone HS, Sather HN, Trigg ME, Uckun FM, Bleyer WA. PMID: 9452280.
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    164. Biology and treatment of childhood T-lineage acute lymphoblastic leukemia. Blood. 1998 Feb 01; 91(3):735-46. Uckun FM, Sensel MG, Sun L, Steinherz PG, Trigg ME, Heerema NA, Sather HN, Reaman GH, Gaynon PS. PMID: 9446631.
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    165. Early response to therapy and outcome in childhood acute lymphoblastic leukemia: a review. Cancer. 1997 Nov 01; 80(9):1717-26. Gaynon PS, Desai AA, Bostrom BC, Hutchinson RJ, Lange BJ, Nachman JB, Reaman GH, Sather HN, Steinherz PG, Trigg ME, Tubergen DG, Uckun FM. PMID: 9351539.
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    166. Prognostic significance of the CD10+CD19+CD34+ B-progenitor immunophenotype in children with acute lymphoblastic leukemia: a report from the Children's Cancer Group. Leuk Lymphoma. 1997 Nov; 27(5-6):445-57. Uckun FM, Sather H, Gaynon P, Arthur D, Nachman J, Sensel M, Steinherz P, Hutchinson R, Trigg M, Reaman G. PMID: 9477126.
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    167. A phase II study of carboplatin as a treatment for children with acute leukemia recurring in bone marrow: a report of the Children's Cancer Group. Cancer. 1997 Jul 15; 80(2):311-6. Ettinger LJ, Ivy P, Gaynon PS, Ettinger AG, Liu-Mares W, Krailo MD. PMID: 9217045.
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    168. Importance of the day 7 bone marrow biopsy as a prognostic measure of the outcome in children with acute lymphoblastic leukemia. Med Pediatr Oncol. 1997 Jul; 29(1):16-22. Schultz KR, Massing B, Spinelli JJ, Gaynon PS, Wadsworth L. PMID: 9142200.
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    169. Clinical features and treatment outcome of children with myeloid antigen positive acute lymphoblastic leukemia: a report from the Children's Cancer Group. Blood. 1997 Jul 01; 90(1):28-35. Uckun FM, Sather HN, Gaynon PS, Arthur DC, Trigg ME, Tubergen DG, Nachman J, Steinherz PG, Sensel MG, Reaman GH. PMID: 9207434.
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    170. Expression of BCR-ABL, E2A-PBX1, and MLL-AF4 fusion transcripts in newly diagnosed children with acute lymphoblastic leukemia: a Children's Cancer Group initiative. Leuk Lymphoma. 1997 Jun; 26(1-2):57-65. Gaynon PS, Crotty ML, Sather HN, Bostrom BC, Nachman JB, Steinherz PG, Heerema NA, Sarquis M, Tuel-Ahlgren L, Uckun FM. PMID: 9250788.
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    171. Clinical features and treatment outcome of childhood T-lineage acute lymphoblastic leukemia according to the apparent maturational stage of T-lineage leukemic blasts: a Children's Cancer Group study. J Clin Oncol. 1997 Jun; 15(6):2214-21. Uckun FM, Gaynon PS, Sensel MG, Nachman J, Trigg ME, Steinherz PG, Hutchinson R, Bostrom BC, Sather HN, Reaman GH. PMID: 9196133.
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    172. Augmented Berlin-Frankfurt-Munster therapy abrogates the adverse prognostic significance of slow early response to induction chemotherapy for children and adolescents with acute lymphoblastic leukemia and unfavorable presenting features: a report from the Children's Cancer Group. J Clin Oncol. 1997 Jun; 15(6):2222-30. Nachman J, Sather HN, Gaynon PS, Lukens JN, Wolff L, Trigg ME. PMID: 9196134.
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    173. Cellular expression of antiapoptotic BCL-2 oncoprotein in newly diagnosed childhood acute lymphoblastic leukemia: a Children's Cancer Group Study. Blood. 1997 May 15; 89(10):3769-77. Uckun FM, Yang Z, Sather H, Steinherz P, Nachman J, Bostrom B, Crotty L, Sarquis M, Ek O, Zeren T, Tubergen D, Reaman G, Gaynon P. PMID: 9160683.
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    174. Clinical features and treatment outcome of children with biphenotypic CD2+ CD19+ acute lymphoblastic leukemia: a Children's Cancer Group study. Blood. 1997 Apr 01; 89(7):2488-93. Uckun FM, Gaynon P, Sather H, Arthur D, Trigg M, Tubergen D, Nachman J, Steinherz P, Sensel MG, Reaman GR. PMID: 9116293.
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    175. Acute lymphoblastic leukaemia: a guide to asparaginase and pegaspargase therapy. BioDrugs. 1997 Jan; 7(1):30-9. Ettinger LJ, Ettinger AG, Avramis VI, Gaynon PS. PMID: 18031078.
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    176. Improved clinical outcome for children with T-lineage acute lymphoblastic leukemia after contemporary chemotherapy: a Children's Cancer Group Study. Leuk Lymphoma. 1996 Dec; 24(1-2):57-70. Uckun FM, Reaman G, Steinherez PG, Arthur DC, Sather H, Trigg M, Tubergen D, Gaynon P. PMID: 9049962.
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    177. CD2 antigen expression on leukemic cells as a predictor of event-free survival after chemotherapy for T-lineage acute lymphoblastic leukemia: a Children's Cancer Group study. Blood. 1996 Dec 01; 88(11):4288-95. Uckun FM, Steinherz PG, Sather H, Trigg M, Arthur D, Tubergen D, Gaynon P, Reaman G. PMID: 8943865.
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    178. Craniospinal irradiation for acute lymphoblastic leukemia with central nervous system disease at diagnosis: a report from the Children's Cancer Group. Int J Radiat Oncol Biol Phys. 1996 Aug 01; 36(1):19-27. Cherlow JM, Sather H, Steinherz P, Gaynon P, Tubergen D, Trigg M, Novak L, Bleyer WA. PMID: 8823255.
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    179. Cytoreduction and prognosis in acute lymphoblastic leukemia--the importance of early marrow response: report from the Childrens Cancer Group. J Clin Oncol. 1996 Feb; 14(2):389-98. Steinherz PG, Gaynon PS, Breneman JC, Cherlow JM, Grossman NJ, Kersey JH, Johnstone HS, Sather HN, Trigg ME, Chappell R, Hammond D, Bleyer WA. PMID: 8636748.
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    180. Uniform approach to risk classification and treatment assignment for children with acute lymphoblastic leukemia. J Clin Oncol. 1996 Jan; 14(1):18-24. Smith M, Arthur D, Camitta B, Carroll AJ, Crist W, Gaynon P, Gelber R, Heerema N, Korn EL, Link M, Murphy S, Pui CH, Pullen J, Reamon G, Sallan SE, Sather H, Shuster J, Simon R, Trigg M, Tubergen D, Uckun F, Ungerleider R. PMID: 8558195.
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    181. Acute leukemia in children. Curr Opin Hematol. 1995 Jul; 2(4):240-6. Gaynon PS. PMID: 9372003.
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    182. Tibial stress fracture mimicking neuroblastoma metastasis in two young children. Skeletal Radiol. 1995 May; 24(4):287-90. Tuite MJ, De Smet AA, Gaynon PS. PMID: 7644943.
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    183. Leukemic cell growth in SCID mice as a predictor of relapse in high-risk B-lineage acute lymphoblastic leukemia. Blood. 1995 Feb 15; 85(4):873-8. Uckun FM, Sather H, Reaman G, Shuster J, Land V, Trigg M, Gunther R, Chelstrom L, Bleyer A, Gaynon P, et al. PMID: 7849309.
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    184. The use of glucocorticoids in acute lymphoblastic leukemia of childhood. Molecular, cellular, and clinical considerations. J Pediatr Hematol Oncol. 1995 Feb; 17(1):1-12. Gaynon PS, Lustig RH. PMID: 7743230.
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    185. Carboplatin in pediatric malignancies. Semin Oncol. 1994 Oct; 21(5 Suppl 12):65-76. Gaynon PS. PMID: 7992069.
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    186. A phase II study of carboplatin in children with recurrent or progressive solid tumors. A report from the Childrens Cancer Group. Cancer. 1994 Feb 15; 73(4):1297-301. Ettinger LJ, Gaynon PS, Krailo MD, Ru N, Baum ES, Siegel SE, Hammond GD. PMID: 8313334.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCTClinical Trials
    187. The role of radiation therapy in the treatment of acute lymphoblastic leukemia with lymphomatous presentation: a report from the Childrens Cancer Group. Int J Radiat Oncol Biol Phys. 1993 Dec 01; 27(5):1001-9. Cherlow JM, Steinherz PG, Sather HN, Gaynon PS, Grossman NJ, Kersey JH, Johnstone HS, Breneman JC, Trigg ME, Hammond GD. PMID: 8262820.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    188. Improved therapy for children with acute lymphoblastic leukemia and unfavorable presenting features: a follow-up report of the Childrens Cancer Group Study CCG-106. J Clin Oncol. 1993 Nov; 11(11):2234-42. Gaynon PS, Steinherz PG, Bleyer WA, Ablin AR, Albo VC, Finklestein JZ, Grossman NJ, Novak LJ, Pyesmany AF, Reaman GH, et al. PMID: 8229139.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCTClinical Trials
    189. A phase I study of carboplatin in children with acute leukemia in bone marrow relapse. A report from the Childrens Cancer Group. Cancer. 1993 Aug 01; 72(3):917-22. Ettinger LJ, Krailo MD, Gaynon PS, Hammond GD. PMID: 8334645.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCTClinical Trials
    190. Young adults 16-21 years of age at diagnosis entered on Childrens Cancer Group acute lymphoblastic leukemia and acute myeloblastic leukemia protocols. Results of treatment. Cancer. 1993 May 15; 71(10 Suppl):3377-85. Nachman J, Sather HN, Buckley JD, Gaynon PS, Steinherz PG, Tubergen DG, Lampkin BC, Hammond GD. PMID: 8490886.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    191. Association of delivered drug dose and outcome for children with acute lymphoblastic leukemia and unfavorable presenting features. Med Pediatr Oncol. 1991; 19(4):221-7. Gaynon PS, Steinherz PG, Bleyer WA, Finklestein JZ, Miller DR, Reaman GH, Sather HN, Hammond GD. PMID: 2056967.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    192. Prolonged response to carboplatin in an infant with brain stem glioma. Cancer. 1991 Jan 01; 67(1):43-7. Zeltzer PM, Epport K, Nelson MD, Huff K, Gaynon P. PMID: 1985722.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    193. Granulocytic sarcoma of the ileum treated by bone marrow transplantation. Am J Pediatr Hematol Oncol. 1991; 13(1):34-8. Kowal-Vern A, Johnson FL, Trujillo Y, Nachman J, Radhakrishnan J, Conard P, Gaynon P. PMID: 2029076.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    194. Carboplatin in childhood brain tumors. A Children's Cancer Study Group Phase II trial. Cancer. 1990 Dec 15; 66(12):2465-9. Gaynon PS, Ettinger LJ, Baum ES, Siegel SE, Krailo MD, Hammond GD. PMID: 2249186.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCTClinical Trials
    195. Primary treatment of childhood acute lymphoblastic leukemia of non-T cell lineage (including infants). Hematol Oncol Clin North Am. 1990 Oct; 4(5):915-36. Gaynon PS. PMID: 2262485.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    196. Day 7 marrow response and outcome for children with acute lymphoblastic leukemia and unfavorable presenting features. Med Pediatr Oncol. 1990; 18(4):273-9. Gaynon PS, Bleyer WA, Steinherz PG, Finklestein JZ, Littman P, Miller DR, Reaman G, Sather H, Hammond GD. PMID: 2355886.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    197. Intensive therapy for children with acute lymphoblastic leukaemia and unfavourable presenting features. Early conclusions of study CCG-106 by the Childrens Cancer Study Group. Lancet. 1988 Oct 22; 2(8617):921-4. Gaynon PS, Steinherz PG, Bleyer WA, Ablin AR, Albo VC, Finklestein JZ, Grossman NJ, Littman PS, Novak LT, Pyesmany AF, et al. PMID: 2902379.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCTClinical Trials
    198. The effect of initial management of hyperleukocytosis on early complications and outcome of children with acute lymphoblastic leukemia. J Clin Oncol. 1988 Sep; 6(9):1425-32. Maurer HS, Steinherz PG, Gaynon PS, Finklestein JZ, Sather HN, Reaman GH, Bleyer WA, Hammond GD. PMID: 3166486.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansPHPublic Health
    199. Modified BFM therapy for children with previously untreated acute lymphoblastic leukemia and unfavorable prognostic features. Report of Children's Cancer Study Group Study CCG-193P. Am J Pediatr Hematol Oncol. 1988; 10(1):42-50. Gaynon PS, Bleyer WA, Steinherz PG, Finklestein JZ, Littman PS, Miller DR, Reaman GH, Sather HN, Hammond GD. PMID: 3056061.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    200. Pediatric phase I trial of carboplatin: a Childrens Cancer Study Group report. Cancer Treat Rep. 1987 Nov; 71(11):1039-42. Gaynon PS, Ettinger LJ, Moel D, Siegel SE, Baum ES, Krivit W, Hammond GD. PMID: 3315195.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    201. Improved survival of infants less than 1 year of age with acute lymphoblastic leukemia treated with intensive multiagent chemotherapy. Cancer Treat Rep. 1987 Nov; 71(11):1033-8. Reaman GH, Steinherz PG, Gaynon PS, Bleyer WA, Finklestein JZ, Evans R, Miller DR, Sather HN, Hammond GD. PMID: 3315194.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    202. Microcomputer-assisted data management for multiinstitutional pediatric clinical cancer trials. Am J Pediatr Hematol Oncol. 1987; 9(1):33-41. Gaynon PS, Baum ES, Samsel C, Sather H. PMID: 3473944.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    203. Strategies for the treatment of children with acute lymphoblastic leukemia and unfavorable presenting features. Haematol Blood Transfus. 1987; 30:167-72. Gaynon PS, Steinherz PG, Reaman GH, Bleyer WA, Sather H, Hammond GD. PMID: 3305193.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    204. Improved disease-free survival of children with acute lymphoblastic leukemia at high risk for early relapse with the New York regimen--a new intensive therapy protocol: a report from the Childrens Cancer Study Group. J Clin Oncol. 1986 May; 4(5):744-52. Steinherz PG, Gaynon P, Miller DR, Reaman G, Bleyer A, Finklestein J, Evans RG, Meyers P, Steinherz LJ, Sather H, et al. PMID: 3517244.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCTClinical Trials
    205. Cerebral gigantism associated with Wilms' tumor. Am J Dis Child. 1984 May; 138(5):486-8. Maldonado V, Gaynon PS, Poznanski AK. PMID: 6324572.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    206. Exaggerated eosinophilia and acute lymphoid leukemia. Am J Pediatr Hematol Oncol. 1984; 6(3):334-7. Gaynon PS, Gonzalez-Crussi F. PMID: 6595948.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    207. Continuous infusion of 5-azacytidine as induction for acute nonlymphocytic leukemia in patients with previous exposure to 5-azacytidine. Oncology. 1983; 40(3):192-4. Gaynon PS, Baum ES. PMID: 6189042.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    208. Phase II trial of prednimustine in children with recurrent cancer: a Children's Cancer Study Group report. Cancer Treat Rep. 1982 Jul; 66(7):1583-4. Gaynon PS, Baum ES, Krivit W, Hammond D. PMID: 6284362.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    209. Phase II trail cisplatin in refractory childhood cancer: Children's Cancer Study Group Report. Cancer Treat Rep. 1981 Sep-Oct; 65(9-10):815-22. Baum ES, Gaynon P, Greenberg L, Krivit W, Hammond D. PMID: 6944156.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    210. Profile of a dictionary compiled from scanning over one million words of surgical pathology narrative text. Comput Biomed Res. 1980 Aug; 13(4):382-98. Wong RL, Reno JD, Hain TC, Platt RC, Gaynon PS, Joseph DM. PMID: 6996906.
      View in: PubMed   Mentions: 2     Fields:    
    211. Phase II study of cis-dichlorodiammineplatinum(II) in childhood osteosarcoma: Children's Cancer Study Group Report. Cancer Treat Rep. 1979 Sep-Oct; 63(9-10):1621-7. Baum ES, Gaynon P, Greenberg L, Krivit W, Hammond D. PMID: 291484.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    212. A computer-based system for management of clinical and laboratory data of a comprehensive sickle cell center. Methods Inf Med. 1974 Oct; 13(4):216. Gaynon P, Honig GR. PMID: 4437396.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    213. POLARS: a Pathology On-line Logging And Reporting System. Comput Biomed Res. 1974 Feb; 7(1):83-99. Platt RC, Wong RL, Lantner KW, Gaynon PS. PMID: 4817288.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    214. A retrieval system for a library of pathology reports, slides and kodachromes. Methods Inf Med. 1972 Jul; 11(3):152-62. Gaynon P, Wong RL. PMID: 4114655.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    215. An automated parsing routine for diagnostic statements of surgical pathology reports. Methods Inf Med. 1971 Jul; 10(3):168-75. Wong RL, Gaynon P. PMID: 4937156.
      View in: PubMed   Mentions: 2     Fields:    
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