Jonathan Santoro

Title(s)Associate Professor Of Clinical Neurology and Pediatrics
SchoolKeck School of Medicine of Usc
AddressCHLA 4650 W. Sunset Blvd., MS #82
Off Campus
Los Angeles CA 90026
ORCID ORCID Icon0000-0002-8350-8234 Additional info
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    Collapse Biography 
    Collapse Education and Training
    Tulane University, New Orleans, LABS05/2007Neuroscience
    Tulan University, New Orleans, LAMS05/2008Neuroscience
    Tulane University, New Orleans, LAMD05/2013Medicine
    Stanford University, Palo Alto, CA06/2015Pediatrics Residency
    Stanford University, Palo Alto, CA06/2018Child Neurology Residency
    Harvard University, Boston, MA06/2019Neuroimmunology Fellowship

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Development and Validation of the Down Syndrome Regression Rating Scales
    NIH R01HD113711Sep 20, 2023 - Aug 31, 2028
    Role: Co-Investigator
    Mechanistic investigation of therapies for Down Syndrome Regression Disorder
    NIH R61HD109748Sep 9, 2022 - Jun 30, 2024
    Role: Co-Investigator
    Non-invasive biometric screening for cerebrovascular disorders in persons with Down syndrome.
    NIH K23HL155898Feb 17, 2021 - Jan 31, 2026
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Evidence of blood-brain barrier dysfunction and CSF immunoglobulin synthesis in Down Syndrome Regression Disorder. Ann Clin Transl Neurol. 2025 Feb 25. Santoro JD, Eduthan NP, Khoshnood MM, Jafarpour S, Boyd NK, Vogel BN, Nguyen L, Kazerooni L, Britton E, Lyford HR, Galbraith MD, Rachubinski AL, Espinosa JM. PMID: 39996411.
      View in: PubMed   Mentions:    Fields:    
    2. Immunotherapy Responsive Recurrent Post-Infectious Ataxia Associated With Recurrent ATP2B2 Gene Variant. Neurol Genet. 2025 Feb; 11(1):e200239. Vancura J, Banerjee AK, Boyd NK, Kazerooni L, Nishimori NA, Ferris R, Vogel BN, Nguyen L, Santoro JD. PMID: 39834499; PMCID: PMC11744605.
      View in: PubMed   Mentions:
    3. Correction: Jean Aicardi (1926-2015). J Neurol. 2025 Jan 09; 272(1):105. Huang A, Jafarpour S, Nishimori NA, Kazerooni L, Santoro JD. PMID: 39786646; PMCID: PMC11717840.
      View in: PubMed   Mentions:    Fields:    
    4. Diagnostic abnormalities, disease severity and immunotherapy responsiveness in individuals with Down syndrome regression disorder. Sci Rep. 2024 12 28; 14(1):30865. Santoro JD, Jafarpour S, Keehan L, Khoshnood MM, Kazerooni L, Boyd NK, Vogel BN, Nguyen L, Manning M, Nagesh D, Spinazzi NA, Besterman AD, Quinn EA, Rafii MS. PMID: 39730779; PMCID: PMC11680819.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Safety and Tolerability of Home Infusions in Down Syndrome Regression Disorder. Clin Ther. 2025 Feb; 47(2):e27-e33. Santoro JD, Nguyen L, Nishimori NA, Ferris R, Vogel BN, Boyd NK, Kazerooni L, Pia S, Khoshnood MM, Jafarpour S. PMID: 39690018.
      View in: PubMed   Mentions:    Fields:    
    6. Central nervous system manifestations in acute and chronic graft-versus-host disease. Brain. 2024 Oct 23. Lambert N, Forte F, El Moussaoui M, Monseur J, Raus N, Polushin A, Michonneau D, Shultz C, Hogan WJ, Balaguer-Roselló A, Gil-Perotìn S, Brijs J, Chauvet P, Gavriilaki M, Carre M, Dulamea AO, Chalandon Y, Salmenniemi U, Duminuco A, Ram R, García-Cadenas I, Porto G, Nguyen S, Smallbone P, González-Vicent M, Santoro JD, Willems E, Baron F, Servais S, Beguin Y, Maquet P, CNS-GvHD Study Group . PMID: 39442000.
      View in: PubMed   Mentions:    Fields:    
    7. Jean Aicardi (1926-2015). J Neurol. 2024 Nov; 271(11):7363-7365. Huang A, Jafarpour S, Nishimori NA, Kazerooni L, Santoro JD. PMID: 39254700; PMCID: PMC11561047.
      View in: PubMed   Mentions:    Fields:    
    8. Anti-CD20 Therapy in Children With Severe Epstein-Barr Virus-Associated Meningoencephalitis. J Child Neurol. 2025 Jan; 40(1):61-66. Ahsan S, Jafarpour S, Khoshnood MM, Nagesh D, Ho E, Ahsan N, Santoro JD. PMID: 39234699.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    9. JAK inhibition in Down Syndrome Regression Disorder. J Neuroimmunol. 2024 Oct 15; 395:578442. Rachubinski AL, Patel LR, Sannar EM, Kammeyer RM, Sanders J, Enriquez-Estrada BA, Worek KR, Fidler DJ, Santoro JD, Espinosa JM. PMID: 39216159; PMCID: PMC11533451.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    10. The Neurologist's Guide to Drug Pricing in the United States. Continuum (Minneap Minn). 2024 Aug 01; 30(4):1259-1271. Nair KV, Santoro JD. PMID: 39088295.
      View in: PubMed   Mentions:    Fields:    
    11. Isolated Psychiatric Symptoms in Children With Anti-N-Methyl-d Aspartate Receptor Encephalitis. Pediatr Neurol. 2024 Oct; 159:12-15. Gombolay G, Brenton JN, Yang JH, Stredny CM, Kammeyer R, Fisher KS, Sandweiss AJ, Erickson TA, Kannan V, Otten C, Steriade C, Vu N, Santoro JD, Robles-Lopez K, Goodrich R, Otallah S, Arellano J, Christiana A, Morris M, Gorman MP, Kornbluh AB, Kahn I, Sepeta L, Jiang Y, Muscal E, Murray KO, Moodley M, Hardy D. PMID: 39094249; PMCID: PMC11381152.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. A systematic review of the epidemiology of pediatric autoimmune encephalitis: disease burden and clinical decision-making. Front Neurol. 2024; 15:1408606. Santoro JD, Demakakos P, He S, Kumar S, Murton M, Tennigkeit F, Hemingway C. PMID: 39040538; PMCID: PMC11262030.
      View in: PubMed   Mentions:
    13. Down Syndrome and Autoimmune Disease. Clin Rev Allergy Immunol. 2024 Jun; 66(3):261-273. Hom B, Boyd NK, Vogel BN, Nishimori N, Khoshnood MM, Jafarpour S, Nagesh D, Santoro JD. PMID: 38913142; PMCID: PMC11422465.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    14. De novo variants in immune regulatory genes in Down syndrome regression disorder. J Neurol. 2024 Aug; 271(8):5567-5576. Jafarpour S, Banerjee AK, Khoshnood MM, Vogel BN, Boyd NK, Nguyen L, Partridge R, Santoro SL, Gombolay GY, Fisher KS, de Asua DR, Del Ortega MC, Franklin C, Rafii MS, Santoro JD. PMID: 38909119; PMCID: PMC11319504.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. Sexual Health Education and Quality of Counseling in Pediatric-Onset Multiple Sclerosis. Pediatr Neurol. 2024 Aug; 157:108-113. Burk K, Pagarkar D, Khoshnood MM, Jafarpour S, Ahsan N, Mitchell WG, Santoro JD. PMID: 38905743.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. Delayed initiation of disease modifying therapy increases relapse frequency and motor disability in pediatric onset multiple sclerosis. Mult Scler Relat Disord. 2024 Jul; 87:105669. Jafarpour S, Pinto S, Vu MH, Khoshnood MM, Ahsan N, Saucier LE, Santoro JD. PMID: 38749351.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. Bridging the Divide: An Integrated Neurobio-Psycho-Social Approach to Treating Antibody Negative Inflammatory Encephalitis in a School-Aged Child. Harv Rev Psychiatry. 2024 May-Jun 01; 32(3):101-116. Hawkes C, Dale RC, Scher S, Cornish JL, Perez DL, Santoro JD, Fernandes S, Kozlowska K. PMID: 38728570.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    18. The diagnostic workup of children with the radiologically isolated syndrome differs by age and by sex. J Neurol. 2024 Jul; 271(7):4019-4027. Makhani N, Lebrun-Frenay C, Siva A, Shabanova V, Wassmer E, Santoro JD, Narula S, Brenton JN, Mar S, Durand-Dubief F, Zephir H, Mathey G, Rojas JI, de Seze J, Tenembaum S, Stone RT, Casez O, Carra-Dallière C, Neuteboom RF, Ahsan N, Arroyo HA, Cabre P, Gombolay G, Inglese M, Louapre C, Margoni M, Palavra F, Pohl D, Reich DS, Ruet A, Thouvenot E, Timby N, Tintore M, Uygunoglu U, Vargas W, Venkateswaran S, Verhelst H, Wickstrom R, Azevedo CJ, Kantarci O, Shapiro ED, Okuda DT, Pelletier D, Observatoire Francophone de la Sclérose en Plaques (OFSEP), Société Francophone de la Sclérose en Pl. PMID: 38564056; PMCID: PMC11323224.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    19. Consensus guidelines for the monitoring and management of metachromatic leukodystrophy in the United States. Cytotherapy. 2024 Jul; 26(7):739-748. Adang LA, Bonkowsky JL, Boelens JJ, Mallack E, Ahrens-Nicklas R, Bernat JA, Bley A, Burton B, Darling A, Eichler F, Eklund E, Emrick L, Escolar M, Fatemi A, Fraser JL, Gaviglio A, Keller S, Patterson MC, Orchard P, Orthmann-Murphy J, Santoro JD, Schöls L, Sevin C, Srivastava IN, Rajan D, Rubin JP, Van Haren K, Wasserstein M, Zerem A, Fumagalli F, Laugwitz L, Vanderver A. PMID: 38613540; PMCID: PMC11348704.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    20. Neuropathologic Impacts of JAK Inhibitor Treatment in Aicardi-Goutières Syndrome. J Clin Immunol. 2024 02 21; 44(3):68. Jafarpour S, Suddock J, Hawes D, Santoro JD. PMID: 38381212.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    21. Neuroimaging abnormalities associated with immunotherapy responsiveness in Down syndrome regression disorder. Ann Clin Transl Neurol. 2024 Apr; 11(4):1034-1045. Santoro JD, Khoshnood MM, Jafarpour S, Nguyen L, Boyd NK, Vogel BN, Kammeyer R, Patel L, Manning MA, Rachubinski AL, Filipink RA, Baumer NT, Santoro SL, Franklin C, Tamrazi B, Yeom KW, Worley G, Espinosa JM, Rafii MS. PMID: 38375538; PMCID: PMC11021615.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    22. Prescription Drug Prices: An AAN Position Statement. Neurology. 2024 Mar 12; 102(5):e209132. Santoro JD, Sico JJ, Burke JF, Sarkar K, Turbes M, Evans DA, Jordan JT, AAN Health Policy Subcommittee. PMID: 38335469.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    23. Safety and tolerability of intravenous immunoglobulin infusion in Down syndrome regression disorder. Am J Med Genet A. 2024 05; 194(5):e63524. Santoro JD, Jafarpour S, Khoshnood MM, Boyd NK, Vogel BN, Nguyen L, Saucier LE, Partridge R, Tiongson E, Ramos-Platt L, Nagesh D, Ho E, Rosser T, Ahsan N, Mitchell WG, Rafii MS. PMID: 38169137.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    24. Impact of endocrine dysregulation on disability and non-motor symptoms in pediatric onset multiple sclerosis. Front Neurol. 2023; 14:1304610. Abe J, Jafarpour S, Vu MH, O'Brien D, Boyd NK, Vogel BN, Nguyen L, Paulsen KC, Saucier LE, Ahsan N, Mitchell WG, Santoro JD. PMID: 38130835; PMCID: PMC10733457.
      View in: PubMed   Mentions:
    25. Diagnostic Yield of Epilepsy-Genes Sequencing and Chromosomal Microarray in Pediatric Epilepsy. Pediatr Neurol. 2024 Jan; 150:50-56. Burk KC, Kaneko M, Quindipan C, Vu MH, Cepin MF, Santoro JD, Van Hirtum-Das M, Holder D, Raca G. PMID: 37979304.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    26. Hypovitaminosis D in persons with Down syndrome and autism spectrum disorder. J Neurodev Disord. 2023 10 25; 15(1):35. Boyd NK, Nguyen J, Khoshnood MM, Jiang T, Nguyen L, Mendez L, Spinazzi NA, Manning MA, Rafii MS, Santoro JD. PMID: 37880588; PMCID: PMC10599027.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    27. Rapidly progressive moyamoya vasculopathy stabilized with immunotherapy in aicardi-goutières syndrome. J Neurol. 2024 Feb; 271(2):1019-1022. Vancura J, Boyd NK, Vogel BN, Nagesh D, Ho E, Santoro JD. PMID: 37855872.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    28. Ophthalmologic and neuro-ophthalmologic findings in children with Down syndrome. Am J Med Genet C Semin Med Genet. 2023 12; 193(4):e32068. Jain A, Boyd NK, Paulsen KC, Vogel BN, Nguyen L, Santoro JD. PMID: 37794641.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    29. Brain Magnetic Resonance Imaging Abnormalities in Acute Flaccid Myelitis. Pediatr Neurol. 2023 Dec; 149:56-62. Caceres JA, Saucier L, Murphy OC, Gordon-Lipkin EM, Santoro JD, Van Haren K, Pardo CA, Hopkins S. PMID: 37797356; PMCID: PMC11954972.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    30. Thiamine metabolism dysfunction syndrome 5 (THMD5) mimicking acute disseminated encephalomyelitis. Am J Med Genet A. 2023 12; 191(12):2868-2872. Thompson ZE, Boyd NK, Khoshnood MM, Santoro JD. PMID: 37589194.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    31. Alternative Diagnoses in the Work Up of Down Syndrome Regression Disorder. J Autism Dev Disord. 2023 Aug 16. Santoro JD, Khoshnood MM, Nguyen L, Vogel BN, Boyd NK, Paulsen KC, Rafii MS. PMID: 37584771.
      View in: PubMed   Mentions: 1     Fields:    
    32. Immunotherapy responsiveness and risk of relapse in Down syndrome regression disorder. Transl Psychiatry. 2023 08 08; 13(1):276. Santoro JD, Spinazzi NA, Filipink RA, Hayati-Rezvan P, Kammeyer R, Patel L, Sannar EA, Dwyer L, Banerjee AK, Khoshnood M, Jafarpour S, Boyd NK, Partridge R, Gombolay GY, Christy AL, Real de Asua D, Del Carmen Ortega M, Manning MA, Van Mater H, Worley G, Franklin C, Stanley MA, Brown R, Capone GT, Quinn EA, Rafii MS. PMID: 37553347; PMCID: PMC10409776.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    33. Publisher Correction: Patient Pathway to Diagnosis of Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD): Findings from a Multinational Survey of 204 Patients. Neurol Ther. 2023 Aug; 12(4):1103. Santoro JD, Gould J, Panahloo Z, Thompson E, Lefelar J, Palace J. PMID: 37162722; PMCID: PMC10310650.
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    34. A Case of Pediatric Guillain-Barré Syndrome After Respiratory Syncytial Virus Infection. Pediatr Neurol. 2023 09; 146:129-131. Gupta M, Monjazeb S, Rosser T, Santoro JD, Ahsan N. PMID: 37481934.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    35. The Impact of Neuroimmunologic Disease and Developing Nervous System. Pediatr Neurol. 2023 Nov; 148:189-197. Santoro JD, Jafarpour S, Boyd NK, Nguyen L, Khoshnood MM. PMID: 37442652.
      View in: PubMed   Mentions:    Fields:    
    36. Your note, your way: how to write an inpatient progress note accurately and efficiently as an intern. Postgrad Med J. 2023 Jun 08; 99(1171):492-497. Wei M, Salgado E, Girard CE, Santoro JD, Lepore N. PMID: 37294720.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    37. MRI Features and Their Association With Outcomes in Children With Anti-NMDA Receptor Encephalitis. Neurol Neuroimmunol Neuroinflamm. 2023 07; 10(4). Gombolay G, Brenton JN, Yang JH, Stredny CM, Kammeyer R, Otten CE, Vu N, Santoro JD, Robles-Lopez K, Christiana A, Steriade C, Morris M, Gorman M, Moodley M, Hardy D, Kornbluh AB, Kahn I, Sepeta LN, Yeshokumar A, Conquering Neuroinflammation and Epilepsies Consortium (CONNECT). PMID: 37236807; PMCID: PMC10219134.
      View in: PubMed   Mentions: 4     Fields:    
    38. Myelin Oligodendrocyte Glycoprotein (MOG) Associated Diseases: Updates in Pediatric Practice. Semin Pediatr Neurol. 2023 07; 46:101056. Khoshnood MM, Santoro JD. PMID: 37451753.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    39. Patient Pathway to Diagnosis of Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD): Findings from a Multinational Survey of 204 Patients. Neurol Ther. 2023 Aug; 12(4):1081-1101. Santoro JD, Gould J, Panahloo Z, Thompson E, Lefelar J, Palace J. PMID: 37024731; PMCID: PMC10310677.
      View in: PubMed   Mentions: 3  
    40. Adverse childhood experiences and the development of Down syndrome regression disorder. Am J Med Genet A. 2023 07; 191(7):1769-1782. Wang S, Patel L, Sannar EA, Khoshnood M, Boyd NK, Mendez L, Spinazzi NA, Quinn EA, Rafii MS, Santoro JD. PMID: 37017126.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    41. Attack phenotypes and disease course in pediatric MOGAD. Ann Clin Transl Neurol. 2023 05; 10(5):672-685. Santoro JD, Beukelman T, Hemingway C, Hokkanen SRK, Tennigkeit F, Chitnis T. PMID: 37000895; PMCID: PMC10187731.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    42. Co-occurring conditions in children with Down syndrome and autism: a retrospective study. J Neurodev Disord. 2023 03 02; 15(1):9. Spinazzi NA, Santoro JD, Pawlowski K, Anzueto G, Howe YJ, Patel LR, Baumer NT. PMID: 36864370; PMCID: PMC9979529.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    43. Immunotherapy Responsiveness and Risk of Relapse in Down Syndrome Regression Disorder. Res Sq. 2023 Feb 13. Santoro J, Spinazzi N, Filipink R, Hayati-Rezvan P, Kammeyer R, Patel L, Sannar E, Dwyer L, Banerjee A, Khoshnood M, Jafarpour S, Boyd N, Partridge R, Gombolay G, Christy A, Real de Asua D, Del Carmen Ortega M, Manning M, Van Mater H, Worley G, Franklin C, Stanley M, Brown R, Capone G, Quinn E, Rafii M. PMID: 36824719; PMCID: PMC9949176.
      View in: PubMed   Mentions:
    44. Down syndrome regression disorder: updates and therapeutic advances. Curr Opin Psychiatry. 2023 03 01; 36(2):96-103. Santoro JD, Filipink RA, Baumer NT, Bulova PD, Handen BL. PMID: 36705008.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    45. Innovating Therapies for Down Syndrome: An International Virtual Conference of the T21 Research Society. Mol Syndromol. 2023 Apr; 14(2):89-100. Hamlett ED, Flores-Aguilar L, Handen B, Potier MC, Granholm AC, Sherman S, Puig V, Santoro JD, Carmona-Iragui M, Rebillat AS, Head E, Strydom A, Busciglio J. PMID: 37064334; PMCID: PMC10090974.
      View in: PubMed   Mentions:
    46. Immunotherapy responsive neuroinflammation in a child with FAS-associated death-domain mutation. Clin Genet. 2023 02; 103(2):252-253. Vogel B, Boyd NK, Kuo CY, Kohn LA, Soldatos A, Santoro JD. PMID: 36254101.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    47. The Genetic Landscape of Ischemic Stroke in Children - Current Knowledge and Future Perspectives. Semin Pediatr Neurol. 2022 12; 44:100999. Hausman-Kedem M, Herring R, Torres MD, Santoro JD, Kaseka ML, Vargas C, Amico G, Bertamino M, Nagesh D, Tilley J, Schenk A, Ben-Shachar S, Musolino PL. PMID: 36456039.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    48. Association of rare variants in genes of immune regulation with pediatric autoimmune CNS diseases. J Neurol. 2022 Dec; 269(12):6512-6529. Jafarpour S, Banerjee A, Boyd NK, Vogel BN, Paulsen KC, Ahsan N, Mitchell WG, Jeste SS, Santoro JD. PMID: 35960392; PMCID: PMC9372976.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    49. Assessment and Diagnosis of Down Syndrome Regression Disorder: International Expert Consensus. Front Neurol. 2022; 13:940175. Santoro JD, Patel L, Kammeyer R, Filipink RA, Gombolay GY, Cardinale KM, Real de Asua D, Zaman S, Santoro SL, Marzouk SM, Khoshnood M, Vogel BN, Tanna R, Pagarkar D, Dhanani S, Ortega MDC, Partridge R, Stanley MA, Sanders JS, Christy A, Sannar EM, Brown R, McCormick AA, Van Mater H, Franklin C, Worley G, Quinn EA, Capone GT, Chicoine B, Skotko BG, Rafii MS. PMID: 35911905; PMCID: PMC9335003.
      View in: PubMed   Mentions: 15  
    50. Child Neurology: Neurodegenerative Encephalomyelopathy Associated With ACOX1 Gain-of-Function Variation Partially Responsive to Immunotherapy. Neurology. 2022 08 23; 99(8):341-346. Jafarpour S, Khoshnood M, Santoro JD. PMID: 35715200.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    51. Early Onset Diffusion Abnormalities in Refractory Headache Disorders. Front Neurol. 2022; 13:898219. Santoro JD, Moon PK, Han M, McKenna ES, Tong E, MacEachern SJ, Forkert ND, Yeom KW. PMID: 35775057; PMCID: PMC9237368.
      View in: PubMed   Mentions:
    52. Evidence of neuroinflammation and immunotherapy responsiveness in individuals with down syndrome regression disorder. J Neurodev Disord. 2022 06 03; 14(1):35. Santoro JD, Partridge R, Tanna R, Pagarkar D, Khoshnood M, Rehmani M, Kammeyer RM, Gombolay GY, Fisher K, Conravey A, El-Dahr J, Christy AL, Patel L, Manning MA, Van Mater H, Rafii MS, Quinn EA. PMID: 35659536; PMCID: PMC9164321.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    53. Prognostic indicators and outcomes of hospitalised COVID-19 patients with neurological disease: An individual patient data meta-analysis. PLoS One. 2022; 17(6):e0263595. Singh B, Lant S, Cividini S, Cattrall JWS, Goodwin LC, Benjamin L, Michael BD, Khawaja A, Matos AMB, Alkeridy W, Pilotto A, Lahiri D, Rawlinson R, Mhlanga S, Lopez EC, Sargent BF, Somasundaran A, Tamborska A, Webb G, Younas K, Al Sami Y, Babu H, Banks T, Cavallieri F, Cohen M, Davies E, Dhar S, Fajardo Modol A, Farooq H, Harte J, Hey S, Joseph A, Karthikappallil D, Kassahun D, Lipunga G, Mason R, Minton T, Mond G, Poxon J, Rabas S, Soothill G, Zedde M, Yenkoyan K, Brew B, Contini E, Cysique L, Zhang X, Maggi P, van Pesch V, Lechien J, Saussez S, Heyse A, Brito Ferreira ML, Soares CN, Elicer I, Eugenín-von Bernhardi L, Ñancupil Reyes W, Yin R, Azab MA, Abd-Allah F, Elkady A, Escalard S, Corvol JC, Delorme C, Tattevin P, Bigaut K, Lorenz N, Hornuss D, Hosp J, Rieg S, Wagner D, Knier B, Lingor P, Winkler AS, Sharifi-Razavi A, Moein ST, SeyedAlinaghi S, JamaliMoghadamSiahkali S, Morassi M, Padovani A, Giunta M, Libri I, Beretta S, Ravaglia S, Foschi M, Calabresi P, Primiano G, Servidei S, Biagio Mercuri N, Liguori C, Pierantozzi M, Sarmati L, Boso F, Garazzino S, Mariotto S, Patrick KN, Costache O, Pincherle A, Klok FA, Meza R, Cabreira V, Valdoleiros SR, Oliveira V, Kaimovsky I, Guekht A, Koh J, Fernández Díaz E, Barrios-López JM, Guijarro-Castro C, Beltrán-Corbellini Á, Martínez-Poles J, Diezma-Martín AM, Morales-Casado MI, García García S, Breville G, Coen M, Uginet M, Bernard-Valnet R, Du Pasquier R, Kaya Y, Abdelnour LH, Rice C, Morrison H, Defres S, Huda S, Enright N, Hassell J, D'Anna L, Benger M, Sztriha L, Raith E, Chinthapalli K, Nortley R, Paterson R, Chandratheva A, Werring DJ, Dervisevic S, Harkness K, Pinto A, Jillella D, Beach S, Gunasekaran K, Rocha Ferreira Da Silva I, Nalleballe K, Santoro J, Scullen T, Kahn L, Kim CY, Thakur KT, Jain R, Umapathi T, Nicholson TR, Sejvar JJ, Hodel EM, Brain Infections Global COVID-Neuro Network Study Group, Tudur Smith C, Solomon T. PMID: 35653330; PMCID: PMC9162376.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    54. Intracranial Vascular Tortuosity in an Infant With Dysmorphic Facies. Pediatr Neurol. 2022 06; 131:20-22. Tempchin AF, Nagesh D, Paulsen KC, Ho E, Santoro JD. PMID: 35462107.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    55. International Prevalence and Mechanisms of SARS-CoV-2 in Childhood Arterial Ischemic Stroke During the COVID-19 Pandemic. Stroke. 2022 08; 53(8):2497-2503. Beslow LA, Agner SC, Santoro JD, Ram D, Wilson JL, Harrar D, Appavu B, Fraser SM, Rossor T, Torres MD, Kossorotoff M, Zuñiga Zambrano YC, Hernández-Chávez M, Hassanein SMA, Zafeiriou D, Dowling MM, Kopyta I, Stence NV, Bernard TJ, Dlamini N, International Pediatric Stroke Study Group. PMID: 35380052; PMCID: PMC9311284.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCellsPHPublic Health
    56. Autoimmune Encephalitis. Pediatr Rev. 2022 Apr 01; 43(4):198-211. Jafarpour S, Santoro JD. PMID: 35362030.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    57. Acetazolamide-Challenged Arterial Spin Labeling Detects Augmented Cerebrovascular Reserve After Surgery for Moyamoya. Stroke. 2022 04; 53(4):1354-1362. Rao VL, Prolo LM, Santoro JD, Zhang M, Quon JL, Jin M, Iyer A, Yedavalli V, Lober RM, Steinberg GK, Yeom KW, Grant GA. PMID: 34865510.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    58. Inadequate Vaccine Responses in Children With Multiple Sclerosis. Front Pediatr. 2021; 9:790159. Santoro JD, Saucier LE, Tanna R, Wiegand SE, Pagarkar D, Tempchin AF, Khoshnood M, Ahsan N, Van Haren K. PMID: 34926358; PMCID: PMC8678906.
      View in: PubMed   Mentions: 2  
    59. Increased Autoimmunity in Individuals With Down Syndrome and Moyamoya Disease. Front Neurol. 2021; 12:724969. Santoro JD, Lee S, Wang AC, Ho E, Nagesh D, Khoshnood M, Tanna R, Durazo-Arvizu RA, Manning MA, Skotko BG, Steinberg GK, Rafii MS. PMID: 34566869; PMCID: PMC8455812.
      View in: PubMed   Mentions: 12  
    60. Increased Prevalence of Familial Autoimmune Disease in Children With Opsoclonus-Myoclonus Syndrome. Neurol Neuroimmunol Neuroinflamm. 2021 11; 8(6). Santoro JD, Kerr LM, Codden R, Casper TC, Greenberg BM, Waubant E, Kong SW, Mandl KD, Gorman MP. PMID: 34475249; PMCID: PMC8422990.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    61. Pliny the Elder: Lessons from the Naturalist as an Early Neuroscientist. Neuroscientist. 2023 04; 29(2):150-157. Chu DT, Rosso M, Santoro JD. PMID: 34160310.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    62. Post-infectious inflammatory syndrome associated with SARS-CoV-2 in a paediatric patient with Down syndrome. BMJ Case Rep. 2021 Apr 15; 14(4). Khoshnood M, Mahabir R, Shillingford NM, Santoro JD. PMID: 33858888; PMCID: PMC8054062.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    63. Metabolic stroke-like episode in a child with FARS2 mutation and SARS-CoV-2 positive cerebrospinal fluid. Mol Genet Metab Rep. 2021 Jun; 27:100756. Powers KT, Santoro JD. PMID: 33875935; PMCID: PMC8045429.
      View in: PubMed   Mentions:
    64. Sleep positions in children with Down syndrome and obstructive sleep apnea. Sleep Med. 2021 05; 81:463-465. Santoro JD, Del Rosario J, Osterbauer B, Gillett ES, Don DM. PMID: 33865077.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    65. Underutilization of Contraception in Young Females with Demyelinating Disorders. Mult Scler Relat Disord. 2021 Jun; 51:102881. Santoro JD, Hurtubise B, Rosario JD, Pagarkar D, Wiegand SE, Su E, Ahsan N. PMID: 33730609.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    66. Triad of hypovitaminosis A, hyperostosis, and optic neuropathy in males with autism spectrum disorders. Nutr Neurosci. 2022 Aug; 25(8):1697-1703. Godfrey D, Stone RT, Lee M, Chitnis T, Santoro JD. PMID: 33666531.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    67. Immunotherapy responsive SARS-CoV-2 infection exacerbating opsoclonus myoclonus syndrome. Mult Scler Relat Disord. 2021 May; 50:102855. Wiegand SE, Mitchell WG, Santoro JD. PMID: 33677410; PMCID: PMC7899919.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    68. Myelin oligodendrocyte glycoprotein antibody encephalitis following severe acute respiratory syndrome coronavirus 2 in a pediatric patient. Clin Exp Pediatr. 2021 Jun; 64(6):310-312. Ahsan N, Jafarpour S, Santoro JD. PMID: 33539698; PMCID: PMC8181016.
      View in: PubMed   Mentions: 15  
    69. William Gordon Lennox (1884-1960). J Neurol. 2021 Sep; 268(9):3512-3513. Rosso M, Chu D, Santoro JD. PMID: 33417002.
      View in: PubMed   Mentions: 1     Fields:    
    70. Biotinidase Deficiency as a Mimic of Neuromyelitis Optica Spectrum Disorder in Childhood. JAMA Neurol. 2020 Oct 05. Santoro JD, Paulsen KC. PMID: 33016994; PMCID: PMC7536621.
      View in: PubMed   Mentions: 3     Fields:    
    71. Down syndrome with co-occurring Marfan syndrome. BMJ Case Rep. 2020 Sep 23; 13(9). Wei M, Lepore N, Paulsen K, Santoro JD. PMID: 32967946; PMCID: PMC7513568.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    72. Neurologic complications of Down syndrome: a systematic review. J Neurol. 2021 Dec; 268(12):4495-4509. Santoro JD, Pagarkar D, Chu DT, Rosso M, Paulsen KC, Levitt P, Rafii MS. PMID: 32920658.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    73. MOG-IgG1 and co-existence of neuronal autoantibodies. Mult Scler. 2021 07; 27(8):1175-1186. Kunchok A, Flanagan EP, Krecke KN, Chen JJ, Caceres JA, Dominick J, Ferguson I, Kinkel R, Probasco JC, Ruvalcaba M, Santoro JD, Sieloff K, Timothy J, Weinshenker BG, McKeon A, Pittock SJ. PMID: 32907470; PMCID: PMC8454216.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    74. Bell's palsy in a pediatric patient with hyper IgM syndrome and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Brain Dev. 2021 Feb; 43(2):357-359. Theophanous C, Santoro JD, Itani R. PMID: 32950319; PMCID: PMC7472970.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    75. Pediatric Multiple Sclerosis Severity Score in a large US cohort. Neurology. 2020 09 29; 95(13):e1844-e1853. Santoro JD, Waltz M, Aaen G, Belman A, Benson L, Gorman M, Goyal MS, Graves JS, Harris Y, Krupp L, Lotze T, Mar S, Moodley M, Ness J, Rensel M, Rodriguez M, Schreiner T, Tillema JM, Waubant E, Weinstock-Guttman B, Hurtubise BF, Roalstad S, Rose J, Casper TC, Chitnis T, US Network of Pediatric MS Centers. PMID: 32690790; PMCID: PMC7682820.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    76. Down Syndrome Disintegrative Disorder: A Clinical Regression Syndrome of Increasing Importance. Pediatrics. 2020 06; 145(6). Rosso M, Fremion E, Santoro SL, Oreskovic NM, Chitnis T, Skotko BG, Santoro JD. PMID: 32471843.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    77. Genetic Acute Necrotizing Encephalopathy Associated with RANBP2: Clinical and Therapeutic Implications in Pediatrics. Mult Scler Relat Disord. 2020 Aug; 43:102194. Levine JM, Ahsan N, Ho E, Santoro JD. PMID: 32426208; PMCID: PMC7228726.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    78. Reader response: Characteristics of graduating US allopathic medical students pursuing a career in neurology. Neurology. 2020 04 28; 94(17):762-763. Santoro JD. PMID: 32341201.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    79. Diminished Blood Pressure Profiles in Children With Down Syndrome. Hypertension. 2020 03; 75(3):819-825. Santoro JD, Lee S, Mlynash M, Mayne EW, Rafii MS, Skotko BG. PMID: 31928114.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    80. A Probable Case of Recurrent Bickerstaff Brainstem Encephalitis With Fulminant Course in a Pediatric Patient. Neurologist. 2020 Jan; 25(1):14-16. Chamsi Basha A, Kolko N, Santoro JD, Alomani H. PMID: 31876654.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    81. Children with epilepsy demonstrate macro- and microstructural changes in the thalamus, putamen, and amygdala. Neuroradiology. 2020 Mar; 62(3):389-397. MacEachern SJ, Santoro JD, Hahn KJ, Medress ZA, Stecher X, Li MD, Hahn JS, Yeom KW, Forkert ND. PMID: 31853588.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    82. HHV-6-Associated Neurological Disease in Children: Epidemiologic, Clinical, Diagnostic, and Treatment Considerations. Pediatr Neurol. 2020 04; 105:10-20. Eliassen E, Hemond CC, Santoro JD. PMID: 31932119.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    83. Wilhelm Uhthoff and Uhthoff's phenomenon. Mult Scler. 2020 11; 26(13):1790-1796. Jain A, Rosso M, Santoro JD. PMID: 31621479.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    84. Diagnostic Considerations in Acute Disseminated Encephalomyelitis and the Interface with MOG Antibody. Neuropediatrics. 2019 10; 50(5):273-279. Santoro JD, Chitnis T. PMID: 31340401; PMCID: PMC7117081.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    85. Ketamine use in refractory status epilepticus associated with anti-NMDA receptor antibody encephalitis. Epilepsy Behav Rep. 2019; 12:100326. Santoro JD, Filippakis A, Chitnis T. PMID: 31453565; PMCID: PMC6657533.
      View in: PubMed   Mentions: 11  
    86. Cluster Randomized Controlled Trial of Disability Education Module During Clinical Clerkship. Clin Pediatr (Phila). 2019 11; 58(13):1387-1393. Santoro JD, Whitgob EE, Huffman LC. PMID: 31113214.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    87. Strokelike Episodes in a Patient With Chronic Gait Abnormalities. JAMA Neurol. 2019 05 01; 76(5):621-622. Santoro JD, Chitnis T. PMID: 30801629.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    88. Long-term Sequelae of Pediatric Bickerstaff Brainstem Encephalitis Includes Autonomic and Sleep Dysregulation. J Child Neurol. 2019 03; 34(3):153-160. Santoro JD. PMID: 30604651.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    89. Commentary. J Neurosci Rural Pract. 2019 Jan-Mar; 10(1):162-163. Santoro JD, Santoro TN. PMID: 30765997; PMCID: PMC6337974.
      View in: PubMed   Mentions:
    90. Jacques Jean Lhermitte and Lhermitte's sign. Mult Scler. 2020 04; 26(4):501-504. Chu DT, Hautecoeur P, Santoro JD. PMID: 30570397.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    91. Racial Bias in the US Opioid Epidemic: A Review of the History of Systemic Bias and Implications for Care. Cureus. 2018 Dec 14; 10(12):e3733. Santoro TN, Santoro JD. PMID: 30800543; PMCID: PMC6384031.
      View in: PubMed   Mentions: 57  
    92. Pioneers in neurology: Michel Jouvet (1925-2017). J Neurol. 2019 10; 266(10):2590-2591. Castro-Mendoza PB, Chu DT, Santoro JD. PMID: 30536107.
      View in: PubMed   Mentions:    Fields:    
    93. Safety, tolerability, and efficacy of fluoxetine as an antiviral for acute flaccid myelitis. Neurology. 2019 04 30; 92(18):e2118-e2126. Messacar K, Sillau S, Hopkins SE, Otten C, Wilson-Murphy M, Wong B, Santoro JD, Treister A, Bains HK, Torres A, Zabrocki L, Glanternik JR, Hurst AL, Martin JA, Schreiner T, Makhani N, DeBiasi RL, Kruer MC, Tremoulet AH, Van Haren K, Desai J, Benson LA, Gorman MP, Abzug MJ, Tyler KL, Dominguez SR. PMID: 30413631; PMCID: PMC6512883.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    94. Human herpesvirus 6 associated post-transplant acute limbic encephalitis: Clinical observations of biomarkers for risk of seizure in a pediatric population. Transpl Infect Dis. 2019 Feb; 21(1):e13003. Santoro JD, Hemond CC. PMID: 30256500.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    95. 50 Years Ago in The Journal of Pediatrics: Abnormally Small Head Size and Intellect in Children. J Pediatr. 2018 10; 201:159. Santoro JD. PMID: 30244726.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    96. Blood Pressure Elevation and Risk of Moyamoya Syndrome in Patients With Trisomy 21. Pediatrics. 2018 10; 142(4). Santoro JD, Lee S, Mlynash M, Nguyen T, Lazzareschi DV, Kraler LD, Mayne EW, Steinberg GK. PMID: 30190347.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    97. Use of electronic medical record templates improves quality of care for patients with infantile spasms. Health Inf Manag. 2021 Jan-May; 50(1-2):47-54. Santoro JD, Sandoval Karamian AG, Ruzhnikov M, Brimble E, Chadwick W, Wusthoff CJ. PMID: 30124080.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    98. Continued Presence of Period Limb Movements During REM Sleep in Patients With Chronic Static Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS). J Clin Sleep Med. 2018 07 15; 14(7):1187-1192. Santoro JD, Frankovich J, Bhargava S. PMID: 29991427; PMCID: PMC6040797.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    99. Ethics of End of Life Decisions in Pediatrics: A Narrative Review of the Roles of Caregivers, Shared Decision-Making, and Patient Centered Values. Behav Sci (Basel). 2018 Apr 26; 8(5). Santoro JD, Bennett M. PMID: 29701637; PMCID: PMC5981236.
      View in: PubMed   Mentions: 15  
    100. Refractory focal epilepsy in a paediatric patient with primary familial brain calcification. Seizure. 2018 Mar; 56:50-52. Knowles JK, Santoro JD, Porter BE, Baumer FM. PMID: 29448117; PMCID: PMC5899664.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    101. Pediatric Bickerstaff brainstem encephalitis: a systematic review of literature and case series. J Neurol. 2018 Jan; 265(1):141-150. Santoro JD, Lazzareschi DV, Campen CJ, Van Haren KP. PMID: 29177548.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    102. Child Neurology Residency-Finding the Right Fit. Pediatr Neurol. 2017 02; 67:3-6. Santoro JD, Fisher PG. PMID: 27908656.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    103. Edwin Bickerstaff (1920-2008). J Neurol. 2017 Mar; 264(3):619-620. Yedla M, Lazzareschi DV, Santoro JD. PMID: 27671481.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    104. Assessing the Immunogenic Response of a Single Center's Pneumococcal Vaccination Protocol in Sickle Cell Disease. J Pediatr Hematol Oncol. 2016 Apr; 38(3):e102-6. Santoro JD, Myers L, Kanter J. PMID: 26886376; PMCID: PMC4801650.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansPHPublic Health
    105. Iodine Supplementation for Pediatric Patients Receiving Long-Term Parenteral Nutrition. Nutr Clin Pract. 2016 Apr; 31(2):245-9. Santoro JD, Nespor C, Poole RL, Kerner JA. PMID: 26507189.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    106. Multimodality Renal Failure in a Patient with OEIS Complex. AJP Rep. 2015 Oct; 5(2):e161-4. Santoro JD, Chao S, Hsieh MH, Lee HC. PMID: 26495176; PMCID: PMC4603852.
      View in: PubMed   Mentions:
    107. Pulmonary nocardiosis in an immunocompetent patient with cystic fibrosis. Case Rep Pulmonol. 2015; 2015:984171. Schoen L, Santoro JD, Milla C, Bhargava S. PMID: 25960909; PMCID: PMC4414227.
      View in: PubMed   Mentions: 2  
    108. A case of rhabdomyolysis in the presence of multiple risk factors and dextroamphetamine use. Am J Med Sci. 2013 Jun; 345(6):494-6. Santoro JD, Black JM, Hamm LL. PMID: 23276898.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    109. A case of invasive Streptococcus pneumoniae in an afebrile adolescent with sickle cell disease. Clin Pediatr (Phila). 2013 Dec; 52(12):1173-5. Santoro JD, Case AE, El-Dahr J, Kanter J. PMID: 23589086.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    110. Diagnosis and management of urinary tract infections in neonates and young infants. Clin Pediatr (Phila). 2013 Feb; 52(2):111-4. Santoro JD, Carroll VG, Steele RW. PMID: 23378477.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
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