Laura A. Kalayjian, MD

Title(s)Associate Professor of Clinical Neurology, Director, Neurophysiology Lab LAC + USC Medical Center
SchoolKeck School of Medicine of Usc
AddressHCC 3rd Floor Room 3000
Health Sciences Campus
Los Angeles CA 90089-9405
Phone+1 323 442 5710
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    Collapse Biography 
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    Pasadena Magazine 2011Top Doctor

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    Dr. Laura Kalayjian is Chief of Neurology and Director of the EEG Lab at LAC+USC Medical Center. She completed medical school at the University of Massachusetts in Worcester, MA and completed her neurology residency at Stanford University, Palo Alto, CA. She was fellowship trained in epilepsy and neurophysiology under Dr. Martha Morrell at Columbia Presbyterian, New York. She accepted a position at USC in July 2000. She has been active as co-director of the comprehensive epilepsy program and continues to pursue her research interests in women with epilepsy, hormonal influences and pregnancy and quality of life issues in persons with epilepsy.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Association of Prenatal Exposure to Antiseizure Medications With Creative and Executive Function at Age 4.5 Years. Neurology. 2024 Jun 25; 102(12):e209448. Meador KJ, Cohen MJ, Loring DW, Matthews AG, Brown CA, Robalino C, Carmack A, Sumners S, Birnbaum AK, Kalayjian LA, Gedzelman E, Voinescu PE, Gerard EE, Hanna J, Cavitt J, Sam M, Hwang ST, Pack AM, Tsai JJ, Pennell PB, Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs Investigator Group. PMID: 38810172; PMCID: PMC11226309.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Behavioral Outcomes and Neurodevelopmental Disorders Among Children of Women With Epilepsy. JAMA Neurol. 2024 Jan 01; 81(1):19-29. Cohen MJ, Meador KJ, Loring DW, Matthews AG, Brown C, Robalino CP, Birnbaum AK, Voinescu PE, Kalayjian LA, Gerard EE, Gedzelman ER, Hanna J, Cavitt J, Sam MC, French JA, Hwang ST, Pack AM, Pennell PB, Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD) Investigator Group. PMID: 37983058; PMCID: PMC10660252.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    3. Initiation and Duration of Breastfeeding in the Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs Study. Neurology. 2023 Nov 27; 101(22):e2266-e2276. Gerard EE, Meador KJ, Robalino CP, Brown CA, Matthews AG, Voinescu PE, Kalayjian LA, Gedzelman E, Hanna J, Cavitt J, Sam M, French JA, Pack AM, Hwang ST, Tsai JJ, Taylor C, Pennell PB, MONEAD Investigator Study Group. PMID: 37816636; PMCID: PMC10727216.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    4. Cognitive outcomes at age 3 years in children with fetal exposure to antiseizure medications (MONEAD study) in the USA: a prospective, observational cohort study. Lancet Neurol. 2023 08; 22(8):712-722. Meador KJ, Cohen MJ, Loring DW, Matthews AG, Brown C, Robalino CP, Birnbaum AK, Voinescu PE, Kalayjian LA, Gerard EE, Gedzelman ER, Hanna J, Cavitt J, Sam M, French JA, Hwang S, Pack AM, Pennell PB, MONEAD Investigator Group. PMID: 37479375; PMCID: PMC10423009.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    5. Assessing the efficacy of magnesium oxide and riboflavin as preventative treatment of migraines in pregnancy. Arch Gynecol Obstet. 2023 12; 308(6):1749-1754. Mazza GR, Solorio C, Stek AM, Kalayjian LA, Wilson ML, Gordon BJ. PMID: 36495328.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. Effect of Epilepsy on Sleep Quality During Pregnancy and Postpartum. Neurology. 2022 Oct 10; 99(15):e1584-e1597. Toprani S, Meador KJ, Robalino CP, Brown CA, Matthews AG, Gerard EE, Penovich P, Gedzelman E, Cavitt J, Hwang ST, Kalayjian LA, Sam M, Pack A, Pennell PB, MONEAD. PMID: 35853745; PMCID: PMC9559942.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Prospective Cohort Study of Depression During Pregnancy and the Postpartum Period in Women With Epilepsy vs Control Groups. Neurology. 2022 10 11; 99(15):e1573-e1583. Meador KJ, Stowe ZN, Brown C, Robalino CP, Matthews AG, Kalayjian LA, Voinescu PE, Gerard EE, Penovich P, Gedzelman ER, Cavitt J, Pennell PB, MONEAD Investigator Group. PMID: 35977832; PMCID: PMC9559950.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    8. Altered adult neurogenesis and gliogenesis in patients with mesial temporal lobe epilepsy. Nat Neurosci. 2022 04; 25(4):493-503. Ammothumkandy A, Ravina K, Wolseley V, Tartt AN, Yu PN, Corona L, Zhang N, Nune G, Kalayjian L, Mann JJ, Rosoklija GB, Arango V, Dwork AJ, Lee B, Smith JAD, Song D, Berger TW, Heck C, Chow RH, Boldrini M, Liu CY, Russin JJ, Bonaguidi MA. PMID: 35383330; PMCID: PMC9097543.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    9. Antiseizure Medication Concentrations During Pregnancy: Results From the Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD) Study. JAMA Neurol. 2022 04 01; 79(4):370-379. Pennell PB, Karanam A, Meador KJ, Gerard E, Kalayjian L, Penovich P, Matthews A, McElrath TM, Birnbaum AK, MONEAD Study Group. PMID: 35157004; PMCID: PMC8845026.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    10. Two-Year-Old Cognitive Outcomes in Children of Pregnant Women With Epilepsy in the Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs Study. JAMA Neurol. 2021 08 01; 78(8):927-936. Meador KJ, Cohen MJ, Loring DW, May RC, Brown C, Robalino CP, Matthews AG, Kalayjian LA, Gerard EE, Gedzelman ER, Penovich PE, Cavitt J, Hwang S, Sam M, Pack AM, French J, Tsai JJ, Pennell PB, Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs Investigator Group. PMID: 34096986; PMCID: PMC8185630.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    11. Changes in Seizure Frequency and Antiepileptic Therapy during Pregnancy. N Engl J Med. 2020 12 24; 383(26):2547-2556. Pennell PB, French JA, May RC, Gerard E, Kalayjian L, Penovich P, Gedzelman E, Cavitt J, Hwang S, Pack AM, Sam M, Miller JW, Wilson SH, Brown C, Birnbaum AK, Meador KJ, MONEAD Study Group. PMID: 33369356; PMCID: PMC7919187.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    12. Pregnancy outcomes of refractory epilepsy patients treated with Brain-responsive neurostimulation. Epilepsy Res. 2021 01; 169:106532. Li Y, Eliashiv D, LaHue SC, Rao VR, Martini ML, Panov F, Oster JM, Yoshii-Contreras J, Skidmore CT, Kalayjian LA, Millett D, Meador KJ. PMID: 33360540.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    13. Antiepileptic Drug Exposure in Infants of Breastfeeding Mothers With Epilepsy. JAMA Neurol. 2020 04 01; 77(4):441-450. Birnbaum AK, Meador KJ, Karanam A, Brown C, May RC, Gerard EE, Gedzelman ER, Penovich PE, Kalayjian LA, Cavitt J, Pack AM, Miller JW, Stowe ZN, Pennell PB, MONEAD Investigator Group. PMID: 31886825; PMCID: PMC6990802.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    14. Fetal loss and malformations in the MONEAD study of pregnant women with epilepsy. Neurology. 2020 04 07; 94(14):e1502-e1511. Meador KJ, Pennell PB, May RC, Van Marter L, McElrath TF, Brown C, Gerard E, Kalayjian L, Gedzelman E, Penovich P, Cavitt J, French J, Hwang S, Pack AM, Sam M, Birnbaum AK, Finnell R, MONEAD Investigator Group. PMID: 31806691; PMCID: PMC7251524.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    15. Dual responsive neurostimulation implants for epilepsy. J Neurosurg. 2020 01 01; 132(1):225-231. Barbaro MF, Chesney K, Kramer DR, Kellis S, Peng T, Blumenfeld Z, Gogia AS, Lee MB, Greenwood J, Nune G, Kalayjian LA, Heck CN, Liu CY, Lee B. PMID: 30684944.
      View in: PubMed   Mentions: 1     Fields:    
    16. Fetal antiepileptic drug exposure and learning and memory functioning at 6 years of age: The NEAD prospective observational study. Epilepsy Behav. 2019 03; 92:154-164. Cohen MJ, Meador KJ, May R, Loblein H, Conrad T, Baker GA, Bromley RL, Clayton-Smith J, Kalayjian LA, Kanner A, Liporace JD, Pennell PB, Privitera M, Loring DW, NEAD Study Group. PMID: 30660966.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    17. Changes in antiepileptic drug-prescribing patterns in pregnant women with epilepsy. Epilepsy Behav. 2018 07; 84:10-14. Meador KJ, Pennell PB, May RC, Gerard E, Kalayjian L, Velez-Ruiz N, Penovich P, Cavitt J, French J, Hwang S, Pack AM, Sam M, Moore E, Ippolito DM, MONEAD Investigator Group. PMID: 29730500; PMCID: PMC6016834.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    18. A Single-Center Experience with the NeuroPace RNS System: A Review of Techniques and Potential Problems. World Neurosurg. 2015 Sep; 84(3):719-26. Lee B, Zubair MN, Marquez YD, Lee DM, Kalayjian LA, Heck CN, Liu CY. PMID: 25940211.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    19. Valproate and pregnancy: think again. Neurology. 2015 Jan 27; 84(4):e25-6. Kalayjian LA. PMID: 25628438.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. Predictive factors of neurological complications and one-month mortality after liver transplantation. Front Neurol. 2014; 5:275. Fu KA, DiNorcia J, Sher L, Velani SA, Akhtar S, Kalayjian LA, Sanossian N. PMID: 25566180; PMCID: PMC4269112.
      View in: PubMed   Mentions: 7  
    21. Breastfeeding in children of women taking antiepileptic drugs: cognitive outcomes at age 6 years. JAMA Pediatr. 2014 Aug; 168(8):729-36. Meador KJ, Baker GA, Browning N, Cohen MJ, Bromley RL, Clayton-Smith J, Kalayjian LA, Kanner A, Liporace JD, Pennell PB, Privitera M, Loring DW, Neurodevelopmental Effects of Antiepileptic Drugs (NEAD) Study Group. PMID: 24934501; PMCID: PMC4122685.
      View in: PubMed   Mentions: 50     Fields:    Translation:Humans
    22. Fetal antiepileptic drug exposure: Adaptive and emotional/behavioral functioning at age 6years. Epilepsy Behav. 2013 Nov; 29(2):308-15. Cohen MJ, Meador KJ, Browning N, May R, Baker GA, Clayton-Smith J, Kalayjian LA, Kanner A, Liporace JD, Pennell PB, Privitera M, Loring DW, NEAD study group. PMID: 24012508; PMCID: PMC3902100.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    23. Fetal antiepileptic drug exposure and cognitive outcomes at age 6 years (NEAD study): a prospective observational study. Lancet Neurol. 2013 Mar; 12(3):244-52. Meador KJ, Baker GA, Browning N, Cohen MJ, Bromley RL, Clayton-Smith J, Kalayjian LA, Kanner A, Liporace JD, Pennell PB, Privitera M, Loring DW, NEAD Study Group. PMID: 23352199; PMCID: PMC3684942.
      View in: PubMed   Mentions: 193     Fields:    Translation:HumansCTClinical Trials
    24. Differential effects of antiepileptic drugs on neonatal outcomes. Epilepsy Behav. 2012 Aug; 24(4):449-56. Pennell PB, Klein AM, Browning N, Baker GA, Clayton-Smith J, Kalayjian LA, Liporace JD, Privitera M, Crawford T, Loring DW, Meador KJ, NEAD Study Group. PMID: 22749607; PMCID: PMC3483041.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    25. Progesterone vs placebo therapy for women with epilepsy: A randomized clinical trial. Neurology. 2012 Jun 12; 78(24):1959-66. Herzog AG, Fowler KM, Smithson SD, Kalayjian LA, Heck CN, Sperling MR, Liporace JD, Harden CL, Dworetzky BA, Pennell PB, Massaro JM, Progesterone Trial Study Group. PMID: 22649214; PMCID: PMC3369508.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCTClinical Trials
    26. Effects of fetal antiepileptic drug exposure: outcomes at age 4.5 years. Neurology. 2012 Apr 17; 78(16):1207-14. Meador KJ, Baker GA, Browning N, Cohen MJ, Bromley RL, Clayton-Smith J, Kalayjian LA, Kanner A, Liporace JD, Pennell PB, Privitera M, Loring DW, NEAD Study Group. PMID: 22491865; PMCID: PMC3324322.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    27. Fetal antiepileptic drug exposure: motor, adaptive, and emotional/behavioral functioning at age 3 years. Epilepsy Behav. 2011 Oct; 22(2):240-6. Cohen MJ, Meador KJ, Browning N, Baker GA, Clayton-Smith J, Kalayjian LA, Kanner A, Liporace JD, Pennell PB, Privitera M, Loring DW. PMID: 21783425; PMCID: PMC3185140.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    28. Variation of seizure frequency with ovulatory status of menstrual cycles. Epilepsia. 2011 Oct; 52(10):1843-8. Herzog AG, Fowler KM, Sperling MR, Liporace JD, Kalayjian LA, Heck CN, Krauss GL, Dworetzky BA, Pennell PB, Progesterone Trial Study Group. PMID: 21756250; PMCID: PMC4572701.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    29. Premenstrual dysphoric disorder in women with epilepsy: relationships to potential epileptic, antiepileptic drug, and reproductive endocrine factors. Epilepsy Behav. 2011 Aug; 21(4):391-6. Herzog AG, Smithson SD, Fowler KM, Krishnamurthy KB, Sundstrom D, Kalayjian LA, Heck CN, Oviedo S, Correl-Leyva G, Garcia E, Gleason KA, Dworetzky BA. PMID: 21724471.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    30. Relationship of child IQ to parental IQ and education in children with fetal antiepileptic drug exposure. Epilepsy Behav. 2011 Jun; 21(2):147-52. Meador KJ, Baker GA, Browning N, Clayton-Smith J, Cohen MJ, Kalayjian LA, Kanner A, Liporace JD, Pennell PB, Privitera M, Loring DW. PMID: 21546316; PMCID: PMC3114203.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    31. Foetal antiepileptic drug exposure and verbal versus non-verbal abilities at three years of age. Brain. 2011 Feb; 134(Pt 2):396-404. Meador KJ, Baker GA, Browning N, Cohen MJ, Clayton-Smith J, Kalayjian LA, Kanner A, Liporace JD, Pennell PB, Privitera M, Loring DW, NEAD Study Group. PMID: 21224309; PMCID: PMC3030767.
      View in: PubMed   Mentions: 52     Fields:    Translation:Humans
    32. Effects of breastfeeding in children of women taking antiepileptic drugs. Neurology. 2010 Nov 30; 75(22):1954-60. Meador KJ, Baker GA, Browning N, Clayton-Smith J, Combs-Cantrell DT, Cohen M, Kalayjian LA, Kanner A, Liporace JD, Pennell PB, Privitera M, Loring DW, NEAD Study Group. PMID: 21106960; PMCID: PMC3014232.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    33. Antiepileptic drug use in women of childbearing age. Epilepsy Behav. 2009 Jul; 15(3):339-43. Meador KJ, Penovich P, Baker GA, Pennell PB, Bromfield E, Pack A, Liporace JD, Sam M, Kalayjian LA, Thurman DJ, Moore E, Loring DW, NEAD Study Group. PMID: 19410654; PMCID: PMC2741411.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    34. Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs. N Engl J Med. 2009 Apr 16; 360(16):1597-605. Meador KJ, Baker GA, Browning N, Clayton-Smith J, Combs-Cantrell DT, Cohen M, Kalayjian LA, Kanner A, Liporace JD, Pennell PB, Privitera M, Loring DW, NEAD Study Group. PMID: 19369666; PMCID: PMC2737185.
      View in: PubMed   Mentions: 189     Fields:    Translation:Humans
    35. In utero antiepileptic drug exposure: fetal death and malformations. Neurology. 2006 Aug 08; 67(3):407-12. Meador KJ, Baker GA, Finnell RH, Kalayjian LA, Liporace JD, Loring DW, Mawer G, Pennell PB, Smith JC, Wolff MC, NEAD Study Group. PMID: 16894099; PMCID: PMC1986655.
      View in: PubMed   Mentions: 77     Fields:    Translation:Humans
    36. Sexual dysfunction, sex steroid hormone abnormalities, and depression in women with epilepsy treated with antiepileptic drugs. Epilepsy Behav. 2005 May; 6(3):360-5. Morrell MJ, Flynn KL, Doñe S, Flaster E, Kalayjian L, Pack AM. PMID: 15820344.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCTClinical Trials
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