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Kai Chen, PhD

Title(s)Associate Professor Of Research Radiology
Phone+1 323 442 3582
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Lin X, Chen K, Tang H, Huang X, Wei C, Xiao Z. Comparison of anchor screw fixation versus mini-plate fixation in unilateral expansive open-door laminoplasty for the treatment of multi-level cervical spondylotic myelopathy. Medicine (Baltimore). 2018 Dec; 97(49):e13534. PMID: 30544458.
      View in: PubMed
    2. Zhang F, Zhu G, Jacobson O, Liu Y, Chen K, Yu G, Ni Q, Fan J, Yang Z, Xu F, Fu X, Wang Z, Ma Y, Niu G, Zhao X, Chen X. Transformative Nanomedicine of an Amphiphilic Camptothecin Prodrug for Long Circulation and High Tumor Uptake in Cancer Therapy. ACS Nano. 2017 09 26; 11(9):8838-8848. PMID: 28858467.
      View in: PubMed
    3. Jadvar H, Park R, Yap LP, Chen K, Hughes L, Conti P. Effect of Androgen on Normal Biodistribution of [18F]-2'-Fluoro-5-methyl-1-beta-D-arabinofuranosyluracil (18F-FMAU) in Athymic Non-tumor-bearing Male Mice. Anticancer Res. 2017 02; 37(2):475-479. PMID: 28179292.
      View in: PubMed
    4. Choi JS, Zhu Y, Li H, Peyda P, Nguyen TT, Shen MY, Yang YM, Zhu J, Liu M, Lee MM, Sun SS, Yang Y, Yu HH, Chen K, Chuang GS, Tseng HR. Cross-Linked Fluorescent Supramolecular Nanoparticles as Finite Tattoo Pigments with Controllable Intradermal Retention Times. ACS Nano. 2017 01 24; 11(1):153-162. PMID: 27997116.
      View in: PubMed
    5. Ma W, Shao Y, Yang W, Li G, Zhang Y, Zhang M, Zuo C, Chen K, Wang J. Evaluation of (188)Re-labeled NGR-VEGI protein for radioimaging and radiotherapy in mice bearing human fibrosarcoma HT-1080 xenografts. Tumour Biol. 2016 Jul; 37(7):9121-9. PMID: 26768609.
      View in: PubMed
    6. Hou S, Choi JS, Garcia MA, Xing Y, Chen KJ, Chen YM, Jiang ZK, Ro T, Wu L, Stout DB, Tomlinson JS, Wang H, Chen K, Tseng HR, Lin WY. Pretargeted Positron Emission Tomography Imaging That Employs Supramolecular Nanoparticles with in Vivo Bioorthogonal Chemistry. ACS Nano. 2016 Jan 26; 10(1):1417-24. PMID: 26731174; PMCID: PMC4893318.
    7. Huang R, Conti PS, Chen K. In Vivo Tumor Angiogenesis Imaging Using Peptide-Based Near-Infrared Fluorescent Probes. Methods Mol Biol. 2016; 1444:73-84. PMID: 27283419.
      View in: PubMed
    8. Liu Z, Chen H, Chen K, Shao Y, Kiesewetter DO, Niu G, Chen X. Boramino acid as a marker for amino acid transporters. Sci Adv. 2015 Sep; 1(8):e1500694. PMID: 26601275.
      View in: PubMed
    9. Jadvar H, Chen K, Ukimura O. Targeted Prostate Gland Biopsy With Combined Transrectal Ultrasound, mpMRI, and 18F-FMAU PET/CT. Clin Nucl Med. 2015 Aug; 40(8):e426-8. PMID: 26018690.
      View in: PubMed
    10. Huang R, Wang M, Zhu Y, Conti PS, Chen K. Development of PET probes for cancer imaging. Curr Top Med Chem. 2015; 15(8):795-819. PMID: 25732787.
      View in: PubMed
    11. Ma W, Li G, Wang J, Yang W, Zhang Y, Conti PS, Chen K. In vivo NIRF imaging-guided delivery of a novel NGR-VEGI fusion protein for targeting tumor vasculature. Amino Acids. 2014 Dec; 46(12):2721-32. PMID: 25182731.
      View in: PubMed
    12. Cheng Y, Zhao J, Qiao W, Chen K. Recent advances in diagnosis and treatment of gliomas using chlorotoxin-based bioconjugates. Am J Nucl Med Mol Imaging. 2014; 4(5):385-405. PMID: 25143859.
      View in: PubMed
    13. Shao Y, Liang W, Kang F, Yang W, Ma X, Li G, Zong S, Chen K, Wang J. 68Ga-labeled cyclic NGR peptide for microPET imaging of CD13 receptor expression. Molecules. 2014 Aug 05; 19(8):11600-12. PMID: 25100253.
      View in: PubMed
    14. Li G, Wang X, Zong S, Wang J, Conti PS, Chen K. MicroPET imaging of CD13 expression using a (64)Cu-labeled dimeric NGR peptide based on sarcophagine cage. Mol Pharm. 2014 Nov 03; 11(11):3938-46. PMID: 25054774.
      View in: PubMed
    15. Shao Y, Liang W, Kang F, Yang W, Ma X, Li G, Zong S, Chen K, Wang J. A direct comparison of tumor angiogenesis with 68Ga-labeled NGR and RGD peptides in HT-1080 tumor xenografts using microPET imaging. Amino Acids. 2014 Oct; 46(10):2355-64. PMID: 24990522.
      View in: PubMed
    16. Li G, Xing Y, Wang J, Conti PS, Chen K. Near-infrared fluorescence imaging of CD13 receptor expression using a novel Cy5.5-labeled dimeric NGR peptide. Amino Acids. 2014 Jun; 46(6):1547-56. PMID: 24652439.
      View in: PubMed
    17. Xing Y, Zhao J, Conti PS, Chen K. Radiolabeled nanoparticles for multimodality tumor imaging. Theranostics. 2014; 4(3):290-306. PMID: 24505237.
      View in: PubMed
    18. Ma W, Kang F, Wang Z, Yang W, Li G, Ma X, Li G, Chen K, Zhang Y, Wang J. (99m)Tc-labeled monomeric and dimeric NGR peptides for SPECT imaging of CD13 receptor in tumor-bearing mice. Amino Acids. 2013 May; 44(5):1337-45. PMID: 23456486.
      View in: PubMed
    19. Chen K, Ma W, Li G, Wang J, Yang W, Yap LP, Hughes LD, Park R, Conti PS. Synthesis and evaluation of 64Cu-labeled monomeric and dimeric NGR peptides for MicroPET imaging of CD13 receptor expression. Mol Pharm. 2013 Jan 07; 10(1):417-27. PMID: 23190134.
      View in: PubMed
    20. Li G, Xiang L, Yang W, Wang Z, Wang J, Chen K. Efficient multicistronic co-expression of hNIS and hTPO in prostate cancer cells for nonthyroidal tumor radioiodine therapy. Am J Nucl Med Mol Imaging. 2012; 2(4):483-98. PMID: 23145364.
      View in: PubMed
    21. Chen K, Wang X, Lin WY, Shen CK, Yap LP, Hughes LD, Conti PS. Strain-Promoted Catalyst-Free Click Chemistry for Rapid Construction of (64)Cu-Labeled PET Imaging Probes. ACS Med Chem Lett. 2012 Dec 13; 3(12):1019-23. PMID: 24900423.
      View in: PubMed
    22. Jadvar H, Yap LP, Park R, Li Z, Chen K, Hughes L, Kouhi A, Conti P. [18F]-2'-Fluoro-5-methyl-1-beta-D-arabinofuranosyluracil (18F-FMAU) in prostate cancer: initial preclinical observations. Mol Imaging. 2012 Sep-Oct; 11(5):426-32. PMID: 22954187.
      View in: PubMed
    23. Chen K, Li Z, Conti PS. Microwave-assisted one-pot radiosynthesis of 2'-deoxy-2'-[18F]fluoro-5-methyl-1-ß-d-arabinofuranosyluracil ([18F]-FMAU). Nucl Med Biol. 2012 Oct; 39(7):1019-25. PMID: 22503457.
      View in: PubMed
    24. Chen K, Sun X, Niu G, Ma Y, Yap LP, Hui X, Wu K, Fan D, Conti PS, Chen X. Evaluation of 64Cu labeled GX1: a phage display peptide probe for PET imaging of tumor vasculature. Mol Imaging Biol. 2012 Feb; 14(1):96-105. PMID: 21360213.
      View in: PubMed
    25. Huang CW, Li Z, Cai H, Chen K, Shahinian T, Conti PS. Design, synthesis and validation of integrin a2ß1-targeted probe for microPET imaging of prostate cancer. Eur J Nucl Med Mol Imaging. 2011 Jul; 38(7):1313-22. PMID: 21350963.
      View in: PubMed
    26. Chen K, Chen X. Integrin targeted delivery of chemotherapeutics. Theranostics. 2011 Feb 17; 1:189-200. PMID: 21547159.
      View in: PubMed
    27. Chen K, Chen X. Positron emission tomography imaging of cancer biology: current status and future prospects. Semin Oncol. 2011 Feb; 38(1):70-86. PMID: 21362517.
      View in: PubMed
    28. Chen K, Yap LP, Park R, Hui X, Wu K, Fan D, Chen X, Conti PS. A Cy5.5-labeled phage-displayed peptide probe for near-infrared fluorescence imaging of tumor vasculature in living mice. Amino Acids. 2012 Apr; 42(4):1329-37. PMID: 21212998.
      View in: PubMed
    29. Chen K, Conti PS. Target-specific delivery of peptide-based probes for PET imaging. Adv Drug Deliv Rev. 2010 Aug 30; 62(11):1005-22. PMID: 20851156.
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    30. Sun X, Niu G, Yan Y, Yang M, Chen K, Ma Y, Chan N, Shen B, Chen X. Phage display-derived peptides for osteosarcoma imaging. Clin Cancer Res. 2010 Aug 15; 16(16):4268-77. PMID: 20570932.
      View in: PubMed
    31. Anderson CJ, Bulte JW, Chen K, Chen X, Khaw BA, Shokeen M, Wooley KL, VanBrocklin HF. Design of targeted cardiovascular molecular imaging probes. J Nucl Med. 2010 May 01; 51 Suppl 1:3S-17S. PMID: 20395345.
      View in: PubMed
    32. Chen K, Chen X. Design and development of molecular imaging probes. Curr Top Med Chem. 2010; 10(12):1227-36. PMID: 20388106.
      View in: PubMed