 Kai Chen, PhD
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| Title(s) | Associate Professor of Research Radiology |
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| School | Keck School of Medicine of USC |
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| Phone | +1 323 442 3582 |
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| vCard | Download vCard |
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 Bibliographic
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Lin X, Chen K, Tang H, Huang X, Wei C, Xiao Z. Comparison of anchor screw fixation versus mini-plate fixation in unilateral expansive open-door laminoplasty for the treatment of multi-level cervical spondylotic myelopathy. Medicine (Baltimore). 2018 Dec; 97(49):e13534. PMID: 30544458.
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Zhang F, Zhu G, Jacobson O, Liu Y, Chen K, Yu G, Ni Q, Fan J, Yang Z, Xu F, Fu X, Wang Z, Ma Y, Niu G, Zhao X, Chen X. Transformative Nanomedicine of an Amphiphilic Camptothecin Prodrug for Long Circulation and High Tumor Uptake in Cancer Therapy. ACS Nano. 2017 09 26; 11(9):8838-8848. PMID: 28858467.
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Jadvar H, Park R, Yap LP, Chen K, Hughes L, Conti P. Effect of Androgen on Normal Biodistribution of [18F]-2'-Fluoro-5-methyl-1-beta-D-arabinofuranosyluracil (18F-FMAU) in Athymic Non-tumor-bearing Male Mice. Anticancer Res. 2017 02; 37(2):475-479. PMID: 28179292.
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Choi JS, Zhu Y, Li H, Peyda P, Nguyen TT, Shen MY, Yang YM, Zhu J, Liu M, Lee MM, Sun SS, Yang Y, Yu HH, Chen K, Chuang GS, Tseng HR. Cross-Linked Fluorescent Supramolecular Nanoparticles as Finite Tattoo Pigments with Controllable Intradermal Retention Times. ACS Nano. 2017 01 24; 11(1):153-162. PMID: 27997116.
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Ma W, Shao Y, Yang W, Li G, Zhang Y, Zhang M, Zuo C, Chen K, Wang J. Evaluation of (188)Re-labeled NGR-VEGI protein for radioimaging and radiotherapy in mice bearing human fibrosarcoma HT-1080 xenografts. Tumour Biol. 2016 Jul; 37(7):9121-9. PMID: 26768609.
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Hou S, Choi JS, Garcia MA, Xing Y, Chen KJ, Chen YM, Jiang ZK, Ro T, Wu L, Stout DB, Tomlinson JS, Wang H, Chen K, Tseng HR, Lin WY. Pretargeted Positron Emission Tomography Imaging That Employs Supramolecular Nanoparticles with in Vivo Bioorthogonal Chemistry. ACS Nano. 2016 Jan 26; 10(1):1417-24. PMID: 26731174; PMCID: PMC4893318.
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Huang R, Conti PS, Chen K. In Vivo Tumor Angiogenesis Imaging Using Peptide-Based Near-Infrared Fluorescent Probes. Methods Mol Biol. 2016; 1444:73-84. PMID: 27283419.
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Liu Z, Chen H, Chen K, Shao Y, Kiesewetter DO, Niu G, Chen X. Boramino acid as a marker for amino acid transporters. Sci Adv. 2015 Sep; 1(8):e1500694. PMID: 26601275; PMCID: PMC4643766.
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Jadvar H, Chen K, Ukimura O. Targeted Prostate Gland Biopsy With Combined Transrectal Ultrasound, mpMRI, and 18F-FMAU PET/CT. Clin Nucl Med. 2015 Aug; 40(8):e426-8. PMID: 26018690.
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Huang R, Wang M, Zhu Y, Conti PS, Chen K. Development of PET probes for cancer imaging. Curr Top Med Chem. 2015; 15(8):795-819. PMID: 25732787.
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Ma W, Li G, Wang J, Yang W, Zhang Y, Conti PS, Chen K. In vivo NIRF imaging-guided delivery of a novel NGR-VEGI fusion protein for targeting tumor vasculature. Amino Acids. 2014 Dec; 46(12):2721-32. PMID: 25182731.
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Cheng Y, Zhao J, Qiao W, Chen K. Recent advances in diagnosis and treatment of gliomas using chlorotoxin-based bioconjugates. Am J Nucl Med Mol Imaging. 2014; 4(5):385-405. PMID: 25143859; PMCID: PMC4138135.
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Shao Y, Liang W, Kang F, Yang W, Ma X, Li G, Zong S, Chen K, Wang J. 68Ga-labeled cyclic NGR peptide for microPET imaging of CD13 receptor expression. Molecules. 2014 Aug 05; 19(8):11600-12. PMID: 25100253.
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Li G, Wang X, Zong S, Wang J, Conti PS, Chen K. MicroPET imaging of CD13 expression using a (64)Cu-labeled dimeric NGR peptide based on sarcophagine cage. Mol Pharm. 2014 Nov 03; 11(11):3938-46. PMID: 25054774.
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Shao Y, Liang W, Kang F, Yang W, Ma X, Li G, Zong S, Chen K, Wang J. A direct comparison of tumor angiogenesis with 68Ga-labeled NGR and RGD peptides in HT-1080 tumor xenografts using microPET imaging. Amino Acids. 2014 Oct; 46(10):2355-64. PMID: 24990522.
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Li G, Xing Y, Wang J, Conti PS, Chen K. Near-infrared fluorescence imaging of CD13 receptor expression using a novel Cy5.5-labeled dimeric NGR peptide. Amino Acids. 2014 Jun; 46(6):1547-56. PMID: 24652439.
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Xing Y, Zhao J, Conti PS, Chen K. Radiolabeled nanoparticles for multimodality tumor imaging. Theranostics. 2014; 4(3):290-306. PMID: 24505237; PMCID: PMC3915092.
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Ma W, Kang F, Wang Z, Yang W, Li G, Ma X, Li G, Chen K, Zhang Y, Wang J. (99m)Tc-labeled monomeric and dimeric NGR peptides for SPECT imaging of CD13 receptor in tumor-bearing mice. Amino Acids. 2013 May; 44(5):1337-45. PMID: 23456486.
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Chen K, Ma W, Li G, Wang J, Yang W, Yap LP, Hughes LD, Park R, Conti PS. Synthesis and evaluation of 64Cu-labeled monomeric and dimeric NGR peptides for MicroPET imaging of CD13 receptor expression. Mol Pharm. 2013 Jan 07; 10(1):417-27. PMID: 23190134.
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Li G, Xiang L, Yang W, Wang Z, Wang J, Chen K. Efficient multicistronic co-expression of hNIS and hTPO in prostate cancer cells for nonthyroidal tumor radioiodine therapy. Am J Nucl Med Mol Imaging. 2012; 2(4):483-98. PMID: 23145364; PMCID: PMC3484425.
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Chen K, Wang X, Lin WY, Shen CK, Yap LP, Hughes LD, Conti PS. Strain-Promoted Catalyst-Free Click Chemistry for Rapid Construction of (64)Cu-Labeled PET Imaging Probes. ACS Med Chem Lett. 2012 Dec 13; 3(12):1019-23. PMID: 24900423; PMCID: PMC4025793.
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Jadvar H, Yap LP, Park R, Li Z, Chen K, Hughes L, Kouhi A, Conti P. [18F]-2'-Fluoro-5-methyl-1-beta-D-arabinofuranosyluracil (18F-FMAU) in prostate cancer: initial preclinical observations. Mol Imaging. 2012 Sep-Oct; 11(5):426-32. PMID: 22954187; PMCID: PMC3443080.
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Chen K, Li Z, Conti PS. Microwave-assisted one-pot radiosynthesis of 2'-deoxy-2'-[18F]fluoro-5-methyl-1-ß-d-arabinofuranosyluracil ([18F]-FMAU). Nucl Med Biol. 2012 Oct; 39(7):1019-25. PMID: 22503457.
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Chen K, Sun X, Niu G, Ma Y, Yap LP, Hui X, Wu K, Fan D, Conti PS, Chen X. Evaluation of 64Cu labeled GX1: a phage display peptide probe for PET imaging of tumor vasculature. Mol Imaging Biol. 2012 Feb; 14(1):96-105. PMID: 21360213.
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Huang CW, Li Z, Cai H, Chen K, Shahinian T, Conti PS. Design, synthesis and validation of integrin a2ß1-targeted probe for microPET imaging of prostate cancer. Eur J Nucl Med Mol Imaging. 2011 Jul; 38(7):1313-22. PMID: 21350963.
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Chen K, Chen X. Integrin targeted delivery of chemotherapeutics. Theranostics. 2011 Feb 17; 1:189-200. PMID: 21547159; PMCID: PMC3086622.
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Chen K, Chen X. Positron emission tomography imaging of cancer biology: current status and future prospects. Semin Oncol. 2011 Feb; 38(1):70-86. PMID: 21362517.
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Chen K, Yap LP, Park R, Hui X, Wu K, Fan D, Chen X, Conti PS. A Cy5.5-labeled phage-displayed peptide probe for near-infrared fluorescence imaging of tumor vasculature in living mice. Amino Acids. 2012 Apr; 42(4):1329-37. PMID: 21212998.
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Chen K, Conti PS. Target-specific delivery of peptide-based probes for PET imaging. Adv Drug Deliv Rev. 2010 Aug 30; 62(11):1005-22. PMID: 20851156.
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Sun X, Niu G, Yan Y, Yang M, Chen K, Ma Y, Chan N, Shen B, Chen X. Phage display-derived peptides for osteosarcoma imaging. Clin Cancer Res. 2010 Aug 15; 16(16):4268-77. PMID: 20570932.
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Anderson CJ, Bulte JW, Chen K, Chen X, Khaw BA, Shokeen M, Wooley KL, VanBrocklin HF. Design of targeted cardiovascular molecular imaging probes. J Nucl Med. 2010 May 01; 51 Suppl 1:3S-17S. PMID: 20395345.
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Chen K, Chen X. Design and development of molecular imaging probes. Curr Top Med Chem. 2010; 10(12):1227-36. PMID: 20388106.
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