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Ellis Fan-Chuin Meng, PhD

Title(s)Professor of Biomedical Engineering
Phone+1 213 740 6952
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    Collapse Biography 
    Collapse Awards and Honors
    NSF Career Award

    Collapse Overview 
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    Ellis Meng is an Associate Professor of biomedical and electrical engineering and chair of the Women in Science and Engineering program in the Viterbi School of Engineering. Dr. Meng directs the Biomedical Microsystems Laboratory which specializes in focuses on advancing medicine using enabling micromachining, micro- sensor and actuator, microfluidic, and microsystems technologies. She completed her graduate work in electrical engineering at the California Institute of Technology in 2003. She is a recipient of the National Science Foundation CAREER and Wallace H. Coulter Foundation Early Career Awards. Ellis was recognized as a 2009 TR35 Young Innovator Under 35 for her work in next generation drug delivery pumps. In 2012, she was names one of the Medical Device and Diagnostic Industry’s MedTech 40 under 40. Dr. Meng is a strong proponent of translation of microtechnologies in medicine; she is an inventor of novel pumping technology that is being commercialized by Fluid Synchrony LLC which she co-founded. She currently serves at the chair of the Viterbi School of Engineering Committee of the Women in Science and Engineering Program. She also an active educator and authored a textbook on bioMEMS. Her professional memberships include Tau Beta Pi, IEEE, ASME, ASEE, and BMES.

    Collapse Research 
    Collapse Research Activities and Funding
    Flexible neural probe arrays for large-scale cortical and subcortical recording
    NIH/NINDS U01NS099703Sep 30, 2016 - Jun 30, 2019
    Role: Principal Investigator
    Wirelessly-operated Implantable MEMS Micropumps for Drug Infusion in Mice
    NIH/NIGMS R21GM104583Aug 20, 2012 - Jun 30, 2015
    Role: Principal Investigator
    Implantable MEMS Drug Delivery Device for Glaucoma Management
    NIH/NEI R21EY018490Sep 1, 2007 - Aug 31, 2010
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Shackleford GM, Mahdi MY, Moats RA, Hawes D, Tran HC, Finlay JL, Hoang TQ, Meng EF, Erdreich-Epstein A. Continuous and bolus intraventricular topotecan prolong survival in a mouse model of leptomeningeal medulloblastoma. PLoS One. 2019; 14(1):e0206394. PMID: 30608927.
      View in: PubMed
    2. Ortigoza-Diaz J, Scholten K, Larson C, Cobo A, Hudson T, Yoo J, Baldwin A, Weltman Hirschberg A, Meng E. Techniques and Considerations in the Microfabrication of Parylene C Microelectromechanical Systems. Micromachines (Basel). 2018 Aug 22; 9(9). PMID: 30424355.
      View in: PubMed
    3. Xu H, Hirschberg AW, Scholten K, Meng E, Berger TW, Song D. Application of Parylene-Based Flexible Multi-Electrode Array for Recording From Subcortical Brain Regions From Behaving Rats. Conf Proc IEEE Eng Med Biol Soc. 2018 Jul; 2018:4599-4602. PMID: 30441376.
      View in: PubMed
    4. Scholten K, Meng E. A review of implantable biosensors for closed-loop glucose control and other drug delivery applications. Int J Pharm. 2018 Jun 15; 544(2):319-334. PMID: 29458204.
      View in: PubMed
    5. Xu H, Hirschberg AW, Scholten K, Berger TW, Song D, Meng E. Acute in vivo testing of a conformal polymer microelectrode array for multi-region hippocampal recordings. J Neural Eng. 2018 Feb; 15(1):016017. PMID: 29044049.
      View in: PubMed
    6. Baldwin A, Yu L, Pratt M, Scholten K, Meng E. Passive, wireless transduction of electrochemical impedance across thin-film microfabricated coils using reflected impedance. Biomed Microdevices. 2017 Sep 25; 19(4):87. PMID: 28948395.
      View in: PubMed
    7. Weltman A, Scholten K, Meng E, Berger TW. Chronic multi-region recording from the rat hippocampus in vivo with a flexible Parylene-based multi-electrode array. Conf Proc IEEE Eng Med Biol Soc. 2017 07; 2017:1716-1719. PMID: 29060217.
      View in: PubMed
    8. Scholten K, Meng E. Electron-beam lithography for polymer bioMEMS with submicron features. Microsyst Nanoeng. 2016; 2:16053. PMID: 31057839.
      View in: PubMed
    9. Hara SA, Kim BJ, Kuo JT, Lee CD, Meng E, Pikov V. Long-term stability of intracortical recordings using perforated and arrayed Parylene sheath electrodes. J Neural Eng. 2016 12; 13(6):066020. PMID: 27819256.
      View in: PubMed
    10. Weltman A, Yoo J, Meng E. Flexible, Penetrating Brain Probes Enabled by Advances in Polymer Microfabrication. Micromachines (Basel). 2016 Oct 04; 7(10). PMID: 30404353.
      View in: PubMed
    11. Kim BJ, Jin W, Baldwin A, Yu L, Christian E, Krieger MD, McComb JG, Meng E. Parylene MEMS patency sensor for assessment of hydrocephalus shunt obstruction. Biomed Microdevices. 2016 10; 18(5):87. PMID: 27589973.
      View in: PubMed
    12. Weltman A, Scholten K, Meng E, Berger TW. A flexible parylene probe for in vivo recordings from multiple subregions of the rat hippocampus. Conf Proc IEEE Eng Med Biol Soc. 2016 08; 2016:2806-2809. PMID: 28268901.
      View in: PubMed
    13. Cobo A, Sheybani R, Tu H, Meng E. A Wireless Implantable Micropump for Chronic Drug Infusion Against Cancer. Sens Actuators A Phys. 2016 Mar 01; 239:18-25. PMID: 26855476.
      View in: PubMed
    14. Sheybani R, Meng E. Acceleration Techniques for Recombination of Gases in Electrolysis Microactuators with Nafion®-Coated Electrocatalyst. Sens Actuators B Chem. 2015 Dec 31; 221:914-922. PMID: 26251561.
      View in: PubMed
    15. Scholten K, Meng E. Materials for microfabricated implantable devices: a review. Lab Chip. 2015 Nov 21; 15(22):4256-72. PMID: 26400550.
      View in: PubMed
    16. Sheybani R, Cobo A, Meng E. Wireless programmable electrochemical drug delivery micropump with fully integrated electrochemical dosing sensors. Biomed Microdevices. 2015 Aug; 17(4):74. PMID: 26149696.
      View in: PubMed
    17. Lee CD, Hara SA, Yu L, Kuo JT, Kim BJ, Hoang T, Pikov V, Meng E. Matrigel coatings for Parylene sheath neural probes. J Biomed Mater Res B Appl Biomater. 2016 Feb; 104(2):357-68. PMID: 25809504.
      View in: PubMed
    18. Cobo A, Sheybani R, Meng E. MEMS: Enabled Drug Delivery Systems. Adv Healthc Mater. 2015 May; 4(7):969-82. PMID: 25703045.
      View in: PubMed
    19. Xu H, Weltman A, Hsiao MC, Scholten K, Meng E, Berger TW, Song D. Design of a flexible parylene-based multi-electrode array for multi-region recording from the rat hippocampus. Conf Proc IEEE Eng Med Biol Soc. 2015; 2015:7139-42. PMID: 26737938.
      View in: PubMed
    20. Meng E, Sheybani R. Micro- and nano-fabricated implantable drug-delivery systems: current state and future perspectives. Ther Deliv. 2014 Nov; 5(11):1167-70. PMID: 25491666.
      View in: PubMed
    21. Yu L, Kim BJ, Meng E. Chronically implanted pressure sensors: challenges and state of the field. Sensors (Basel). 2014 Oct 31; 14(11):20620-44. PMID: 25365461.
      View in: PubMed
    22. Meng E, Sheybani R. Insight: implantable medical devices. Lab Chip. 2014 Sep 07; 14(17):3233-40. PMID: 24903337.
      View in: PubMed
    23. Kuo JT, Li C, Meng E. Fabrication and characterization of a microfluidic module for chemical gradient generation utilizing passive pumping. Conf Proc IEEE Eng Med Biol Soc. 2014; 2014:4415-8. PMID: 25570971.
      View in: PubMed
    24. Sheybani R, Meng E. On-demand wireless infusion rate control in an implantable micropump for patient-tailored treatment of chronic conditions. Conf Proc IEEE Eng Med Biol Soc. 2014; 2014:882-5. PMID: 25570100.
      View in: PubMed
    25. Kim BJ, Kuo JT, Hara SA, Lee CD, Yu L, Gutierrez CA, Hoang TQ, Pikov V, Meng E. 3D Parylene sheath neural probe for chronic recordings. J Neural Eng. 2013 Aug; 10(4):045002. PMID: 23723130.
      View in: PubMed
    26. Song P, Tng DJ, Hu R, Lin G, Meng E, Yong KT. An electrochemically actuated MEMS device for individualized drug delivery: an in vitro study. Adv Healthc Mater. 2013 Aug; 2(8):1170-8. PMID: 23495127.
      View in: PubMed
    27. Kuo JT, Kim BJ, Hara SA, Lee CD, Gutierrez CA, Hoang TQ, Meng E. Novel flexible Parylene neural probe with 3D sheath structure for enhancing tissue integration. Lab Chip. 2013 Feb 21; 13(4):554-61. PMID: 23160191.
      View in: PubMed
    28. Sheybani R, Gensler H, Meng E. A MEMS electrochemical bellows actuator for fluid metering applications. Biomed Microdevices. 2013 Feb; 15(1):37-48. PMID: 22833156.
      View in: PubMed
    29. Meng E, Hoang T. Micro- and nano-fabricated implantable drug-delivery systems. Ther Deliv. 2012 Dec; 3(12):1457-67. PMID: 23323562.
      View in: PubMed
    30. Gianchandani Y, Meng E. Emerging micro- and nanotechnologies at the interface of engineering, science, and medicine for the development of novel drug delivery devices and systems. (Preface). Adv Drug Deliv Rev. 2012 Nov; 64(14):1545-6. PMID: 23000238.
      View in: PubMed
    31. Meng E, Hoang T. MEMS-enabled implantable drug infusion pumps for laboratory animal research, preclinical, and clinical applications. Adv Drug Deliv Rev. 2012 Nov; 64(14):1628-38. PMID: 22926321.
      View in: PubMed
    32. Berger T, Meng E, George S, Khoo M, Marmarelis V, McCulloch A, Cauwenberghs G, Ohno-Machado L, Schultz J, Johnson JP. Southern California: a hotbed of biomedical engineering: nine bioengineers describe their research and why Southern California has the biotech market cornered. IEEE Pulse. 2012 Jul; 3(4):14-21. PMID: 23008840.
      View in: PubMed
    33. Gensler H, Sheybani R, Li PY, Mann RL, Meng E. An implantable MEMS micropump system for drug delivery in small animals. Biomed Microdevices. 2012 Jun; 14(3):483-96. PMID: 22273985.
      View in: PubMed
    34. Hara SA, Kim BJ, Kuo JT, Lee C, Gutierrez CA, Hoang T, Meng E. Pre-implantation electrochemical characterization of a Parylene C sheath microelectrode array probe. Conf Proc IEEE Eng Med Biol Soc. 2012; 2012:5126-9. PMID: 23367082.
      View in: PubMed
    35. Sheybani R, Cabrera-Munoz NE, Sanchez T, Meng E. Design, fabrication, and characterization of an electrochemically-based dose tracking system for closed-loop drug delivery. Conf Proc IEEE Eng Med Biol Soc. 2012; 2012:519-22. PMID: 23365943.
      View in: PubMed
    36. Saati S, Lo R, Li PY, Meng E, Varma R, Humayun MS. Mini drug pump for ophthalmic use. Curr Eye Res. 2010 Mar; 35(3):192-201. PMID: 20373877.
      View in: PubMed
    37. Li PY, Sheybani R, Gutierrez CA, Kuo JT, Meng E. A Parylene Bellows Electrochemical Actuator. J Microelectromech Syst. 2010 Jan 01; 19(1):215-228. PMID: 21318081.
      View in: PubMed
    38. Saati S, Lo R, Li PY, Meng E, Varma R, Humayun MS. Mini drug pump for ophthalmic use. Trans Am Ophthalmol Soc. 2009 Dec; 107:60-70. PMID: 20126483.
      View in: PubMed
    39. Li PY, Givrad TK, Holschneider DP, Maarek JM, Meng E. A Parylene MEMS Electrothermal Valve. J Microelectromech Syst. 2009 Dec; 18(6):1184-1197. PMID: 21350679.
      View in: PubMed
    40. Li PY, Givrad TK, Sheybani R, Holschneider DP, Maarek JM, Meng E. A low power, on demand electrothermal valve for wireless drug delivery applications. Lab Chip. 2010 Jan 07; 10(1):101-10. PMID: 20024057.
      View in: PubMed
    41. Lo R, Li PY, Saati S, Agrawal RN, Humayun MS, Meng E. A passive MEMS drug delivery pump for treatment of ocular diseases. Biomed Microdevices. 2009 Oct; 11(5):959-70. PMID: 19396548.
      View in: PubMed
    42. Meng E, Li PY, Lo R, Sheybani R, Gutierrez C. Implantable MEMS drug delivery pumps for small animal research. Conf Proc IEEE Eng Med Biol Soc. 2009; 2009:6696-8. PMID: 19964178.
      View in: PubMed
    43. Meng E, Gutierrez C. Parylene-based encapsulated fluid MEMS sensors. Conf Proc IEEE Eng Med Biol Soc. 2009; 2009:1039-41. PMID: 19964947.
      View in: PubMed
    44. Lo R, Li PY, Saati S, Agrawal R, Humayun MS, Meng E. A refillable microfabricated drug delivery device for treatment of ocular diseases. Lab Chip. 2008 Jul; 8(7):1027-30. PMID: 18584074.
      View in: PubMed
    45. Tunc M, Cheng X, Ratner BD, Meng E, Humayun M. Reversible thermosensitive glue for retinal implants. Retina. 2007 Sep; 27(7):938-42. PMID: 17891020.
      View in: PubMed
    46. Tooker A, Meng E, Erickson J, Tai YC, Pine J. Biocompatible parylene neurocages. Developing a robust method for live neural network studies. IEEE Eng Med Biol Mag. 2005 Nov-Dec; 24(6):30-3. PMID: 16382802.
      View in: PubMed
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