Ellis Fan-Chuin Meng, PhD

Title(s)Professor of Biomedical Engineering
SchoolViterbi School of Engineering, Bme
AddressDRB 140
University Park Campus
Los Angeles CA 90089-1111
Phone+1 213 740 6952
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    Collapse Biography 
    Collapse Awards and Honors
    NSF Career Award

    Collapse Overview 
    Collapse Overview
    Ellis Meng is an Associate Professor of biomedical and electrical engineering and chair of the Women in Science and Engineering program in the Viterbi School of Engineering. Dr. Meng directs the Biomedical Microsystems Laboratory which specializes in focuses on advancing medicine using enabling micromachining, micro- sensor and actuator, microfluidic, and microsystems technologies. She completed her graduate work in electrical engineering at the California Institute of Technology in 2003. She is a recipient of the National Science Foundation CAREER and Wallace H. Coulter Foundation Early Career Awards. Ellis was recognized as a 2009 TR35 Young Innovator Under 35 for her work in next generation drug delivery pumps. In 2012, she was names one of the Medical Device and Diagnostic Industry’s MedTech 40 under 40. Dr. Meng is a strong proponent of translation of microtechnologies in medicine; she is an inventor of novel pumping technology that is being commercialized by Fluid Synchrony LLC which she co-founded. She currently serves at the chair of the Viterbi School of Engineering Committee of the Women in Science and Engineering Program. She also an active educator and authored a textbook on bioMEMS. Her professional memberships include Tau Beta Pi, IEEE, ASME, ASEE, and BMES.

    Collapse Research 
    Collapse Research Activities and Funding
    Flexible bioelectronic sensors for non-contact detection of obstruction in pediatric vascular shunts
    NIH R21EB028399Jun 1, 2020 - Mar 31, 2022
    Role: Principal Investigator
    A Technology Resource for Polymer Microelectrode Arrays
    NIH U24NS113647Sep 30, 2019 - Jul 31, 2024
    Role: Principal Investigator
    Flexible neural probe arrays for large-scale cortical and subcortical recording
    NIH U01NS099703Sep 30, 2016 - Jun 30, 2021
    Role: Principal Investigator
    Wirelessly-operated Implantable MEMS Micropumps for Drug Infusion in Mice
    NIH R21GM104583Aug 20, 2012 - Jun 30, 2016
    Role: Principal Investigator
    Implantable MEMS Drug Delivery Device for Glaucoma Management
    NIH R21EY018490Sep 1, 2007 - Aug 31, 2010
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Interface-Mediated Neurogenic Signaling: The Impact of Surface Geometry and Chemistry on Neural Cell Behavior for Regenerative and Brain-Machine Interfacing Applications. Adv Mater. 2024 Aug; 36(33):e2401750. Sands I, Demarco R, Thurber L, Esteban-Linares A, Song D, Meng E, Chen Y. PMID: 38961531; PMCID: PMC11326983.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. Polymer Implantable Electrode Foundry: A shared resource for manufacturing polymer-based microelectrodes for neural interfaces. bioRxiv. 2023 Nov 06. Scholten K, Xu H, Lu Z, Jiang W, Ortigoza-Diaz J, Petrossians A, Orler S, Gallonio R, Liu X, Song D, Meng E. PMID: 37986740; PMCID: PMC10659271.
      View in: PubMed   Mentions:
    3. Characterization of thin film Parylene C device curvature and the formation of helices via thermoforming. J Micromech Microeng. 2023 Sep 01; 33(9):095007. Thielen B, Meng E. PMID: 37520061; PMCID: PMC10373221.
      View in: PubMed   Mentions: 2  
    4. A Library of Polymer-based Microelectrode Array Designs for Recording from the Brain of Different Animal Models. Annu Int Conf IEEE Eng Med Biol Soc. 2023 07; 2023:1-4. Xu H, Scholten K, Li Z, Meng E, Song D. PMID: 38083000.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    5. Making a case for endovascular approaches for neural recording and stimulation. J Neural Eng. 2023 01 25; 20(1). Thielen B, Xu H, Fujii T, Rangwala SD, Jiang W, Lin M, Kammen A, Liu C, Selvan P, Song D, Mack WJ, Meng E. PMID: 36603221; PMCID: PMC9928900.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    6. Acute in vivo Recording with a Generic Parylene Microelectrode Array Implanted with Dip-coating Method into the Rat Brain. Annu Int Conf IEEE Eng Med Biol Soc. 2022 07; 2022:214-217. Xu H, Scholten K, Jiang W, Ortigoza-Diaz JL, Lu Z, Liu X, Meng E, Song D. PMID: 36086181.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    7. A Parylene Neural Probe Array for Multi-Region Deep Brain Recordings. J Microelectromech Syst. 2020 Aug; 29(4):499-513. Wang X, Weltman Hirschberg A, Xu H, Slingsby-Smith Z, Lecomte A, Scholten K, Song D, Meng E. PMID: 35663261; PMCID: PMC9164222.
      View in: PubMed   Mentions: 21  
    8. A portable multi-sensor module for monitoring external ventricular drains. Biomed Microdevices. 2021 09 20; 23(4):45. Hudson TQ, Baldwin A, Samiei A, Lee P, McComb JG, Meng E. PMID: 34542705.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. A comparison of insertion methods for surgical placement of penetrating neural interfaces. J Neural Eng. 2021 04 26; 18(4). Thielen B, Meng E. PMID: 33845469; PMCID: PMC8600966.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    10. Bonding methods for chip integration with Parylene devices. J Micromech Microeng. 2021 Apr; 31(4). Yoo J, Meng E. PMID: 35592766; PMCID: PMC9116693.
      View in: PubMed   Mentions: 4  
    11. A 512-Channel Multi-Layer Polymer-Based Neural Probe Array. J Microelectromech Syst. 2020 Oct; 29(5):1054-1058. Scholten K, Larson CE, Xu H, Song D, Meng E. PMID: 33746477; PMCID: PMC7978043.
      View in: PubMed   Mentions: 10  
    12. Interfacing with the Peripheral Nervous System. J Neurosci Methods. 2020 07 01; 340:108745. Scholten K, Meng E, Knaack G, Song D. PMID: 32330467.
      View in: PubMed   Mentions:    Fields:    
    13. Corrigendum to "Acute in vivo testing of a polymer cuff electrode with integrated microfluidic channels for stimulation, recording, and drug delivery on rat sciatic nerve" [J. Neurosci. Methods 336 (April) (2020) 108634]. J Neurosci Methods. 2020 May 15; 338:108696. Elyahoodayan S, Larson C, Cobo A, Meng E, Song D. PMID: 32265070.
      View in: PubMed   Mentions:    Fields:    
    14. Acute in vivo testing of a polymer cuff electrode with integrated microfluidic channels for stimulation, recording, and drug delivery on rat sciatic nerve. J Neurosci Methods. 2020 04 15; 336:108634. Elyahoodayan S, Larson C, Cobo AM, Meng E, Song D. PMID: 32068010.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    15. A review for the peripheral nerve interface designer. J Neurosci Methods. 2020 02 15; 332:108523. Larson CE, Meng E. PMID: 31743684.
      View in: PubMed   Mentions: 38     Fields:    
    16. Continuous and bolus intraventricular topotecan prolong survival in a mouse model of leptomeningeal medulloblastoma. PLoS One. 2019; 14(1):e0206394. Shackleford GM, Mahdi MY, Moats RA, Hawes D, Tran HC, Finlay JL, Hoang TQ, Meng EF, Erdreich-Epstein A. PMID: 30608927; PMCID: PMC6319703.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    17. Techniques and Considerations in the Microfabrication of Parylene C Microelectromechanical Systems. Micromachines (Basel). 2018 Aug 22; 9(9). Ortigoza-Diaz J, Scholten K, Larson C, Cobo A, Hudson T, Yoo J, Baldwin A, Weltman Hirschberg A, Meng E. PMID: 30424355; PMCID: PMC6187609.
      View in: PubMed   Mentions: 35  
    18. Application of Parylene-Based Flexible Multi-Electrode Array for Recording From Subcortical Brain Regions From Behaving Rats. Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul; 2018:4599-4602. Xu H, Hirschberg AW, Scholten K, Meng E, Berger TW, Song D. PMID: 30441376; PMCID: PMC7153783.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    19. A review of implantable biosensors for closed-loop glucose control and other drug delivery applications. Int J Pharm. 2018 Jun 15; 544(2):319-334. Scholten K, Meng E. PMID: 29458204.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    20. Acute in vivo testing of a conformal polymer microelectrode array for multi-region hippocampal recordings. J Neural Eng. 2018 02; 15(1):016017. Xu H, Hirschberg AW, Scholten K, Berger TW, Song D, Meng E. PMID: 29044049; PMCID: PMC5792195.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    21. Passive, wireless transduction of electrochemical impedance across thin-film microfabricated coils using reflected impedance. Biomed Microdevices. 2017 Sep 25; 19(4):87. Baldwin A, Yu L, Pratt M, Scholten K, Meng E. PMID: 28948395.
      View in: PubMed   Mentions: 2     Fields:    
    22. Chronic multi-region recording from the rat hippocampus in vivo with a flexible Parylene-based multi-electrode array. Annu Int Conf IEEE Eng Med Biol Soc. 2017 Jul; 2017:1716-1719. Weltman A, Scholten K, Meng E, Berger TW. PMID: 29060217.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    23. Long-term stability of intracortical recordings using perforated and arrayed Parylene sheath electrodes. J Neural Eng. 2016 12; 13(6):066020. Hara SA, Kim BJ, Kuo JT, Lee CD, Meng E, Pikov V. PMID: 27819256.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    24. Electron-beam lithography for polymer bioMEMS with submicron features. Microsyst Nanoeng. 2016; 2:16053. Scholten K, Meng E. PMID: 31057839; PMCID: PMC6444738.
      View in: PubMed   Mentions: 11  
    25. Flexible, Penetrating Brain Probes Enabled by Advances in Polymer Microfabrication. Micromachines (Basel). 2016 Oct 04; 7(10). Weltman A, Yoo J, Meng E. PMID: 30404353; PMCID: PMC6190320.
      View in: PubMed   Mentions: 61  
    26. Parylene MEMS patency sensor for assessment of hydrocephalus shunt obstruction. Biomed Microdevices. 2016 10; 18(5):87. Kim BJ, Jin W, Baldwin A, Yu L, Christian E, Krieger MD, McComb JG, Meng E. PMID: 27589973.
      View in: PubMed   Mentions: 7     Fields:    Translation:PHPublic Health
    27. A flexible parylene probe for in vivo recordings from multiple subregions of the rat hippocampus. Annu Int Conf IEEE Eng Med Biol Soc. 2016 Aug; 2016:2806-2809. Weltman A, Scholten K, Meng E, Berger TW. PMID: 28268901.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    28. A Wireless Implantable Micropump for Chronic Drug Infusion Against Cancer. Sens Actuators A Phys. 2016 Mar 01; 239:18-25. Cobo A, Sheybani R, Tu H, Meng E. PMID: 26855476; PMCID: PMC4735729.
      View in: PubMed   Mentions: 9  
    29. Acceleration Techniques for Recombination of Gases in Electrolysis Microactuators with Nafion®-Coated Electrocatalyst. Sens Actuators B Chem. 2015 Dec 31; 221:914-922. Sheybani R, Meng E. PMID: 26251561; PMCID: PMC4522938.
      View in: PubMed   Mentions: 5  
    30. Materials for microfabricated implantable devices: a review. Lab Chip. 2015 Nov 21; 15(22):4256-72. Scholten K, Meng E. PMID: 26400550.
      View in: PubMed   Mentions: 45     Fields:    
    31. Wireless programmable electrochemical drug delivery micropump with fully integrated electrochemical dosing sensors. Biomed Microdevices. 2015 Aug; 17(4):74. Sheybani R, Cobo A, Meng E. PMID: 26149696.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    32. Matrigel coatings for Parylene sheath neural probes. J Biomed Mater Res B Appl Biomater. 2016 Feb; 104(2):357-68. Lee CD, Hara SA, Yu L, Kuo JT, Kim BJ, Hoang T, Pikov V, Meng E. PMID: 25809504.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    33. MEMS: Enabled Drug Delivery Systems. Adv Healthc Mater. 2015 May; 4(7):969-82. Cobo A, Sheybani R, Meng E. PMID: 25703045.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    34. Design of a flexible parylene-based multi-electrode array for multi-region recording from the rat hippocampus. Annu Int Conf IEEE Eng Med Biol Soc. 2015; 2015:7139-42. Xu H, Weltman A, Hsiao MC, Scholten K, Meng E, Berger TW, Song D. PMID: 26737938.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    35. Micro- and nano-fabricated implantable drug-delivery systems: current state and future perspectives. Ther Deliv. 2014 Nov; 5(11):1167-70. Meng E, Sheybani R. PMID: 25491666.
      View in: PubMed   Mentions: 2     Fields:    
    36. Chronically implanted pressure sensors: challenges and state of the field. Sensors (Basel). 2014 Oct 31; 14(11):20620-44. Yu L, Kim BJ, Meng E. PMID: 25365461; PMCID: PMC4279503.
      View in: PubMed   Mentions: 44     Fields:    
    37. Insight: implantable medical devices. Lab Chip. 2014 Sep 07; 14(17):3233-40. Meng E, Sheybani R. PMID: 24903337.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    38. On-demand wireless infusion rate control in an implantable micropump for patient-tailored treatment of chronic conditions. Annu Int Conf IEEE Eng Med Biol Soc. 2014; 2014:882-5. Sheybani R, Meng E. PMID: 25570100.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    39. Fabrication and characterization of a microfluidic module for chemical gradient generation utilizing passive pumping. Annu Int Conf IEEE Eng Med Biol Soc. 2014; 2014:4415-8. Kuo JT, Li C, Meng E. PMID: 25570971.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    40. 3D Parylene sheath neural probe for chronic recordings. J Neural Eng. 2013 Aug; 10(4):045002. Kim BJ, Kuo JT, Hara SA, Lee CD, Yu L, Gutierrez CA, Hoang TQ, Pikov V, Meng E. PMID: 23723130.
      View in: PubMed   Mentions: 59     Fields:    Translation:Animals
    41. An electrochemically actuated MEMS device for individualized drug delivery: an in vitro study. Adv Healthc Mater. 2013 Aug; 2(8):1170-8. Song P, Tng DJ, Hu R, Lin G, Meng E, Yong KT. PMID: 23495127.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    42. Novel flexible Parylene neural probe with 3D sheath structure for enhancing tissue integration. Lab Chip. 2013 Feb 21; 13(4):554-61. Kuo JT, Kim BJ, Hara SA, Lee CD, Gutierrez CA, Hoang TQ, Meng E. PMID: 23160191.
      View in: PubMed   Mentions: 37     Fields:    Translation:Cells
    43. A MEMS electrochemical bellows actuator for fluid metering applications. Biomed Microdevices. 2013 Feb; 15(1):37-48. Sheybani R, Gensler H, Meng E. PMID: 22833156; PMCID: PMC3755886.
      View in: PubMed   Mentions: 7     Fields:    
    44. Micro- and nano-fabricated implantable drug-delivery systems. Ther Deliv. 2012 Dec; 3(12):1457-67. Meng E, Hoang T. PMID: 23323562; PMCID: PMC3576846.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    45. Emerging micro- and nanotechnologies at the interface of engineering, science, and medicine for the development of novel drug delivery devices and systems. (Preface). Adv Drug Deliv Rev. 2012 Nov; 64(14):1545-6. Gianchandani Y, Meng E. PMID: 23000238.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    46. MEMS-enabled implantable drug infusion pumps for laboratory animal research, preclinical, and clinical applications. Adv Drug Deliv Rev. 2012 Nov; 64(14):1628-38. Meng E, Hoang T. PMID: 22926321; PMCID: PMC3488150.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimals
    47. Southern California: a hotbed of biomedical engineering: nine bioengineers describe their research and why Southern California has the biotech market cornered. IEEE Pulse. 2012 Jul; 3(4):14-21. Berger T, Meng E, George S, Khoo M, Marmarelis V, McCulloch A, Cauwenberghs G, Ohno-Machado L, Schultz J, Johnson JP. PMID: 23008840.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    48. An implantable MEMS micropump system for drug delivery in small animals. Biomed Microdevices. 2012 Jun; 14(3):483-96. Gensler H, Sheybani R, Li PY, Mann RL, Meng E. PMID: 22273985; PMCID: PMC3348997.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    49. Pre-implantation electrochemical characterization of a Parylene C sheath microelectrode array probe. Annu Int Conf IEEE Eng Med Biol Soc. 2012; 2012:5126-9. Hara SA, Kim BJ, Kuo JT, Lee C, Gutierrez CA, Hoang T, Meng E. PMID: 23367082.
      View in: PubMed   Mentions:    Fields:    
    50. Design, fabrication, and characterization of an electrochemically-based dose tracking system for closed-loop drug delivery. Annu Int Conf IEEE Eng Med Biol Soc. 2012; 2012:519-22. Sheybani R, Cabrera-Munoz NE, Sanchez T, Meng E. PMID: 23365943.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    51. Mini drug pump for ophthalmic use. Curr Eye Res. 2010 Mar; 35(3):192-201. Saati S, Lo R, Li PY, Meng E, Varma R, Humayun MS. PMID: 20373877; PMCID: PMC2888264.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    52. A Parylene Bellows Electrochemical Actuator. J Microelectromech Syst. 2010 Jan 01; 19(1):215-228. Li PY, Sheybani R, Gutierrez CA, Kuo JT, Meng E. PMID: 21318081; PMCID: PMC3035913.
      View in: PubMed   Mentions: 14  
    53. A Parylene MEMS Electrothermal Valve. J Microelectromech Syst. 2009 Dec; 18(6):1184-1197. Li PY, Givrad TK, Holschneider DP, Maarek JM, Meng E. PMID: 21350679; PMCID: PMC3042720.
      View in: PubMed   Mentions: 5  
    54. Mini drug pump for ophthalmic use. Trans Am Ophthalmol Soc. 2009 Dec; 107:60-70. Saati S, Lo R, Li PY, Meng E, Varma R, Humayun MS. PMID: 20126483; PMCID: PMC2814560.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    55. A low power, on demand electrothermal valve for wireless drug delivery applications. Lab Chip. 2010 Jan 07; 10(1):101-10. Li PY, Givrad TK, Sheybani R, Holschneider DP, Maarek JM, Meng E. PMID: 20024057; PMCID: PMC4134919.
      View in: PubMed   Mentions: 2     Fields:    
    56. A passive MEMS drug delivery pump for treatment of ocular diseases. Biomed Microdevices. 2009 Oct; 11(5):959-70. Lo R, Li PY, Saati S, Agrawal RN, Humayun MS, Meng E. PMID: 19396548.
      View in: PubMed   Mentions: 31     Fields:    Translation:Animals
    57. Implantable MEMS drug delivery pumps for small animal research. Annu Int Conf IEEE Eng Med Biol Soc. 2009; 2009:6696-8. Meng E, Li PY, Lo R, Sheybani R, Gutierrez C. PMID: 19964178.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    58. Parylene-based encapsulated fluid MEMS sensors. Annu Int Conf IEEE Eng Med Biol Soc. 2009; 2009:1039-41. Meng E, Gutierrez C. PMID: 19964947.
      View in: PubMed   Mentions:    Fields:    
    59. A refillable microfabricated drug delivery device for treatment of ocular diseases. Lab Chip. 2008 Jul; 8(7):1027-30. Lo R, Li PY, Saati S, Agrawal R, Humayun MS, Meng E. PMID: 18584074.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansPHPublic Health
    60. Reversible thermosensitive glue for retinal implants. Retina. 2007 Sep; 27(7):938-42. Tunc M, Cheng X, Ratner BD, Meng E, Humayun M. PMID: 17891020.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    61. Biocompatible parylene neurocages. Developing a robust method for live neural network studies. IEEE Eng Med Biol Mag. 2005 Nov-Dec; 24(6):30-3. Tooker A, Meng E, Erickson J, Tai YC, Pine J. PMID: 16382802.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
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