Melinda Chang, MD

Title(s)Assistant Professor of Clinical Ophthalmology
SchoolKeck School of Medicine of Usc
Address4640 West Sunset Blvd
Off Campus
Los Angeles CA 90027
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    Collapse Biography 
    Collapse Awards and Honors
    AOA2011Alpha Omega Alpha Honor Medical Society
    Stein Eye Institute2015  - 2017Excellence in Research Award
    ARVO National Eye Institute2016Travel Grant
    Heed2016Heed Ophthalmic Fellow
    North American Neuro-Ophthalmology Society (NANOS)2017Best Fellow Abstract Award

    Collapse Overview 
    Collapse Overview
    Dr. Chang specializes in the management of neurologic disorders that affect the eyes in children, including optic neuritis, idiopathic intracranial hypertension, myasthenia gravis, cortical visual impairment, metabolic and genetic disorders, and brain and optic nerve tumors. She also has an interest in ophthalmologic problems that occur in children with neuro-developmental disorders, such as autism spectrum disorder (ASD). Additionally, she sees patients with general pediatric ophthalmologic concerns, such as amblyopia and strabismus.

    As a dual fellowship trained pediatric and neuro-ophthalmologist, Dr. Chang is committed to providing the highest level of specialty care to children with neurologic and neuro-developmental disorders that affect the eyes. She combines medical and surgical expertise with a translational research program focused on improved understanding and treatment of pediatric neuro-ophthalmologic disorders.

    Dr. Chang completed a double bachelor’s degree in Neuroscience and Kinesiology, graduating summa cum laude from the University of Southern California. She earned her medical degree at Washington University in St. Louis, then completed ophthalmology residency and pediatric ophthalmology fellowship at the Stein Eye Institute at the University of California, Los Angeles. She concluded her training as the first neuro-ophthalmology fellow at the combined Stein Eye Institute-Doheny Eye Institute at UCLA.

    Dr. Chang is a member of the American Academy of Ophthalmology (AAO), American Association of Pediatric Ophthalmology and Strabismus (AAPOS), North American Neuro-Ophthalmology Society (NANOS), and Association for Research in Vision and Ophthalmology (ARVO). She serves as an editor for Cochrane Eyes and Vision, and is a reviewer for numerous journals. She has published in major ophthalmology journals and is the recipient of the prestigious Heed Ophthalmic Fellowship, in addition to institutional and national awards during medical school, residency, and fellowship.

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Reply. Ophthalmology. 2023 Aug; 130(8):e30. Chang MY, Kim SJ, Pineles SL. PMID: 37140506.
      View in: PubMed   Mentions:    Fields:    
    2. Evaluation of Streamed Hardware-to-Software Telemedicine Strabismus Consultations Utilizing Video Glasses. Clin Ophthalmol. 2022; 16:3927-3933. Li J, Nguyen AM, Kolin T, Chang MY, Reid MW, Lee TC, Nallasamy S. PMID: 36471728; PMCID: PMC9719262.
      View in: PubMed   Mentions:
    3. Surgical Treatments to Improve Visual Acuity in Infantile Nystagmus Syndrome: A Report by the American Academy of Ophthalmology. Ophthalmology. 2023 03; 130(3):331-344. Chang MY, Binenbaum G, Heidary G, Cavuoto KM, Morrison DG, Trivedi RH, Kim SJ, Pineles SL. PMID: 36435636; PMCID: PMC9979093.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Effectiveness of Laser Refractive Surgery to Address Anisometropic Amblyogenic Refractive Error in Children: A Report by the American Academy of Ophthalmology. Ophthalmology. 2022 11; 129(11):1323-1331. Cavuoto KM, Chang MY, Heidary G, Morrison DG, Trivedi RH, Binenbaum G, Kim SJ, Pineles SL. PMID: 35987663; PMCID: PMC9982261.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Neovascularization of the optic disc and peripheral retinal ischemia in a child with a novel variant in ALMS1 (Alström syndrome). Am J Ophthalmol Case Rep. 2022 Jun; 26:101506. Chang MY, Borchert MS, Schmidt R, Nagiel A. PMID: 35355858; PMCID: PMC8958466.
      View in: PubMed   Mentions:
    6. Characteristics and Outcomes of Idiopathic and Non-idiopathic Ocular Motor Apraxia in Children. J Pediatr Ophthalmol Strabismus. 2022 Sep-Oct; 59(5):326-331. Chang MY, Grosrenaud P, Borchert MS. PMID: 35192381; PMCID: PMC9840404.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Delayed Diagnosis of Childhood-Onset Huntington Disease in an 8-Year-Old Boy With Ocular Motor Apraxia. J Neuroophthalmol. 2023 Dec 01; 43(4):e304-e305. Im DH, Borchert MS, Chang MY. PMID: 34924521.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Increase in Pediatric Pseudotumor Cerebri Syndrome Emergency Department Visits, Inpatient Admissions, and Surgeries During the COVID-19 Pandemic. J Neuroophthalmol. 2022 03 01; 42(1):e87-e92. Chang MY, Yim CK, Borchert MS. PMID: 34803141; PMCID: PMC9842394.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    9. Paroxysmal tonic upgaze (PTU) associated with CACNA1A mutation and gross motor delay. J AAPOS. 2021 12; 25(6):353-353.e1. Chang MY, Yuen T, Vyas A, Borchert MS. PMID: 34775063.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    10. Validity and reliability of eye tracking for visual acuity assessment in children with cortical visual impairment. J AAPOS. 2021 12; 25(6):334.e1-334.e5. Chang MY, Borchert MS. PMID: 34687876.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    11. Adjustable Sutures in the Treatment of Strabismus: A Report by the American Academy of Ophthalmology. Ophthalmology. 2022 01; 129(1):100-109. Heidary G, Aakalu VK, Binenbaum G, Chang MY, Morrison DG, VanderVeen DK, Lambert SR, Trivedi RH, Galvin JA, Pineles SL. PMID: 34446304; PMCID: PMC10187043.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    12. Etiology and Outcomes of Acquired Pediatric Sixth Nerve Palsies. J Neuroophthalmol. 2022 03 01; 42(1):e254-e259. Chang MY, Borchert MS. PMID: 34417775.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    13. Ophthalmologic characteristics and outcomes of children with cortical visual impairment and cerebral palsy. J AAPOS. 2021 08; 25(4):223.e1-223.e6. West MR, Borchert MS, Chang MY. PMID: 34271208.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    14. Botulinum Toxin Injection for the Treatment of Strabismus: A Report by the American Academy of Ophthalmology. Ophthalmology. 2021 12; 128(12):1766-1776. Binenbaum G, Chang MY, Heidary G, Morrison DG, Trivedi RH, Galvin JA, Pineles SL. PMID: 34176652.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    15. Home- and Office-Based Vergence and Accommodative Therapies for Treatment of Convergence Insufficiency in Children and Young Adults: A Report by the American Academy of Ophthalmology. Ophthalmology. 2021 12; 128(12):1756-1765. Chang MY, Morrison DG, Binenbaum G, Heidary G, Trivedi RH, Galvin JA, Pineles SL. PMID: 34172337.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    16. Prospective Cross-Sectional Study of Repeatability of Peripapillary Capillary Density Measurement Using Optical Coherence Tomography Angiography in Eyes With Optic Nerve and Retinal Vascular Pathology. J Neuroophthalmol. 2022 03 01; 42(1):73-78. Vu AF, Alber SA, Chang MY, Park SS. PMID: 33870951; PMCID: PMC8514563.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    17. Cortical Visual Impairment Treated by Plasmapheresis in a Child With Metronidazole-Induced Encephalopathy. J Neuroophthalmol. 2021 03 01; 41(1):e66-e68. Chang MY, Borchert MS. PMID: 31834198.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    18. Methods of visual assessment in children with cortical visual impairment. Curr Opin Neurol. 2021 02 01; 34(1):89-96. Chang MY, Borchert MS. PMID: 33230032.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    19. Office- or Facility-Based Probing for Congenital Nasolacrimal Duct Obstruction: A Report by the American Academy of Ophthalmology. Ophthalmology. 2021 06; 128(6):920-927. Morrison DG, Binenbaum G, Chang MY, Heidary G, Trivedi RH, Galvin JA, Pineles SL. PMID: 33358412.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    20. Prevalence of Ophthalmologic Diagnoses in Children With Autism Spectrum Disorder Using the Optum Dataset: APopulation-Based Study. Am J Ophthalmol. 2021 01; 221:147-153. Chang MY, Doppee D, Yu F, Perez C, Coleman AL, Pineles SL. PMID: 32896499.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansPHPublic Health
    21. Review of Cohort Studies: A Companion Article to Malmqvist et al "Progression Over 5 Years of Prelaminar Hyperreflective Lines to Optic Disc Drusen in the Copenhagen Child Cohort 2000 Eye Study". J Neuroophthalmol. 2020 09; 40(3):286-291. Tseng VL, Chang MY. PMID: 32796285.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    22. Compartmental Strabismus. J Binocul Vis Ocul Motil. 2020 Jul-Sep; 70(3):71-78. Pineles SL, Chang MY, Velez FG. PMID: 32463321.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    23. Imaging Methods for Differentiating Pediatric Papilledema from Pseudopapilledema: A Report by the American Academy of Ophthalmology. Ophthalmology. 2020 10; 127(10):1416-1423. Chang MY, Binenbaum G, Heidary G, Morrison DG, Galvin JA, Trivedi RH, Pineles SL. PMID: 32386809.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    24. Advances in the evaluation and management of cortical/cerebral visual impairment in children. Surv Ophthalmol. 2020 Nov - Dec; 65(6):708-724. Chang MY, Borchert MS. PMID: 32199940.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    25. Papilledema Treated by Cranial Expansion in a 5-Year-Old Boy with Camurati-Engelmann Syndrome. Ophthalmology. 2019 11; 126(11):1579. Chang MY, Borchert MS. PMID: 31635703.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    26. Ophthalmologic disorders and risk factors in children with autism spectrum disorder. J AAPOS. 2019 12; 23(6):337.e1-337.e6. Chang MY, Gandhi N, O'Hara M. PMID: 31676470.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    27. Risk Factors for Fellow Eye Involvement in Nonarteritic Anterior Ischemic Optic Neuropathy. J Neuroophthalmol. 2019 06; 39(2):147-152. Chang MY, Keltner JL. PMID: 30300257.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    28. Innovative techniques for the treatment of adult strabismus. J AAPOS. 2019 06; 23(3):132-139. Pineles SL, Chang MY, Holmes JM, Kekunnaya R, Özkan SB, Velez FG. PMID: 31004784.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    29. Reply. Ophthalmology. 2018 09; 125(9):e63. Chang MY, Velez FG, Demer JL, Bonelli L, Quiros PA, Arnold AC, Sadun AA, Pineles SL. PMID: 30143103.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    30. Reply. Ophthalmology. 2018 03; 125(3):e24. Chang MY, Velez FG, Demer JL, Bonelli L, Quiros PA, Arnold AC, Sadun AA, Pineles SL. PMID: 29458839.
      View in: PubMed   Mentions:    Fields:    
    31. Surgical interventions for vertical strabismus in superior oblique palsy. Cochrane Database Syst Rev. 2017 11 27; 11:CD012447. Chang MY, Coleman AL, Tseng VL, Demer JL. PMID: 29178265; PMCID: PMC5805462.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    32. Foveal and Peripapillary Vascular Decrement in Migraine With Aura Demonstrated by Optical Coherence Tomography Angiography. Invest Ophthalmol Vis Sci. 2017 10 01; 58(12):5477-5484. Chang MY, Phasukkijwatana N, Garrity S, Pineles SL, Rahimi M, Sarraf D, Johnston M, Charles A, Arnold AC. PMID: 29059314; PMCID: PMC5656414.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    33. Aqueous shunts for glaucoma. Cochrane Database Syst Rev. 2017 07 28; 7:CD004918. Tseng VL, Coleman AL, Chang MY, Caprioli J. PMID: 28750481; PMCID: PMC5580949.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    34. Accuracy of Diagnostic Imaging Modalities for Classifying Pediatric Eyes as Papilledema Versus Pseudopapilledema. Ophthalmology. 2017 12; 124(12):1839-1848. Chang MY, Velez FG, Demer JL, Bonelli L, Quiros PA, Arnold AC, Sadun AA, Pineles SL. PMID: 28732589.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    35. Necrotizing Tenon's capsule infection in a lymphopenic Down syndrome patient following strabismus surgery. J AAPOS. 2017 Aug; 21(4):333-335. Chang MY, Liu W, Glasgow BJ, Isenberg SJ, Velez FG. PMID: 28625468.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    36. Reply. Am J Ophthalmol. 2017 07; 179:210. Velez FG, Chang MY, Pineles SL. PMID: 28528084.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    37. Decreased Binocular Summation in Strabismic Amblyopes and Effect of Strabismus Surgery. Strabismus. 2017 06; 25(2):73-80. Chang MY, Demer JL, Isenberg SJ, Velez FG, Pineles SL. PMID: 28463606; PMCID: PMC6077119.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    38. Pediatric Optic Neuritis. Semin Pediatr Neurol. 2017 05; 24(2):122-128. Chang MY, Pineles SL. PMID: 28941527.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    39. Inferior Rectus Transposition: A Novel Procedure for Abducens Palsy. Am J Ophthalmol. 2017 May; 177:126-130. Velez FG, Chang MY, Pineles SL. PMID: 28254627; PMCID: PMC5410180.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    40. Deformation of Optic Nerve Head and Peripapillary Tissues by Horizontal Duction. Am J Ophthalmol. 2017 Feb; 174:85-94. Chang MY, Shin A, Park J, Nagiel A, Lalane RA, Schwartz SD, Demer JL. PMID: 27751810; PMCID: PMC5812679.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    41. Surgery for superior oblique tendon anteriorization and entrapment following scleral buckle. J AAPOS. 2016 Apr; 20(2):165.e1-2. Chang MY, Yulek F, Pineles SL, Velez FG. PMID: 27079609; PMCID: PMC4860355.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    42. Optic disk drusen in children. Surv Ophthalmol. 2016 Nov - Dec; 61(6):745-758. Chang MY, Pineles SL. PMID: 27033945; PMCID: PMC5042815.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    43. UNTREATED IRIS MELANOMA COMPLICATED BY HYPHEMA AND UNCONTROLLED GLAUCOMA RESPONSIVE TO IODINE-125 BRACHYTHERAPY. Retin Cases Brief Rep. 2016; 10(1):44-7. Chang MY, McCannel CA, McCannel TA. PMID: 26383516.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    44. Adjustable small-incision selective tenotomy and plication for correction of incomitant vertical strabismus and torsion. J AAPOS. 2015 Oct; 19(5):410-6. Chang MY, Pineles SL, Velez FG. PMID: 26486021; PMCID: PMC4637275.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    45. Quality of life in adults with strabismus. Am J Ophthalmol. 2015 Mar; 159(3):539-44.e2. Chang MY, Velez FG, Demer JL, Isenberg SJ, Coleman AL, Pineles SL. PMID: 25498355; PMCID: PMC4329264.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    46. Comparison of uveal melanoma cytopathologic sample retrieval in trans-scleral versus vitrectomy-assisted transvitreal fine needle aspiration biopsy. Br J Ophthalmol. 2014 Dec; 98(12):1654-8. Chang MY, McCannel TA. PMID: 24997179.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    47. Heterogeneity of monosomy 3 in fine needle aspiration biopsy of choroidal melanoma. Mol Vis. 2013; 19:1892-900. Chang MY, Rao NP, Burgess BL, Johnson L, McCannel TA. PMID: 24049435; PMCID: PMC3774574.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    48. Local treatment failure after globe-conserving therapy for choroidal melanoma. Br J Ophthalmol. 2013 Jul; 97(7):804-11. Chang MY, McCannel TA. PMID: 23645818; PMCID: PMC3686322.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    49. Intraoperative ultrasonography-guided positioning of iodine 125 plaque brachytherapy in the treatment of choroidal melanoma. Ophthalmology. 2012 May; 119(5):1073-7. Chang MY, Kamrava M, Demanes DJ, Leu M, Agazaryan N, Lamb J, Moral JN, Almanzor R, McCannel TA. PMID: 22297030.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    50. Multi-year follow-up of fine-needle aspiration biopsy in choroidal melanoma. Ophthalmology. 2012 Mar; 119(3):606-10. McCannel TA, Chang MY, Burgess BL. PMID: 22226884.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
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