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Author Correction: Engineering programmable material-to-cell pathways via synthetic notch receptors to spatially control differentiation in multicellular constructs. Nat Commun. 2024 Aug 01; 15(1):6490.
Garibyan M, Hoffman T, Makaske T, Do SK, Wu Y, Williams BA, March AR, Cho N, Pedroncelli N, Lima RE, Soto J, Jackson B, Santoso JW, Khademhosseini A, Thomson M, Li S, McCain ML, Morsut L. PMID: 39090120; PMCID: PMC11294467.
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PubMed Mentions: Fields:
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Engineering programmable material-to-cell pathways via synthetic notch receptors to spatially control differentiation in multicellular constructs. Nat Commun. 2024 Jul 13; 15(1):5891.
Garibyan M, Hoffman T, Makaske T, Do SK, Wu Y, Williams BA, March AR, Cho N, Pedroncelli N, Lima RE, Soto J, Jackson B, Santoso JW, Khademhosseini A, Thomson M, Li S, McCain ML, Morsut L. PMID: 39003263; PMCID: PMC11246427.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Hypoxic-Normoxic Crosstalk Activates Pro-Inflammatory Signaling in Human Cardiac Fibroblasts and Myocytes in a Post-Infarct Myocardium on a Chip. Adv Healthc Mater. 2024 Jul 12; e2401478.
Khalil NN, Rexius-Hall ML, Gupta D, McCarthy L, Verma R, Kellogg AC, Takamoto K, Xu M, Nejatpoor T, Parker SJ, McCain ML. PMID: 39001626.
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PubMed Mentions: Fields:
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Regulation of oxytocin-induced calcium transients and gene expression in engineered myometrial tissues by tissue architecture and matrix rigidity. Curr Res Physiol. 2023; 6:100108.
Maxey AP, Travis JM, McCain ML. PMID: 38107790; PMCID: PMC10724203.
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Methods for dynamic and whole volume imaging of the zebrafish heart. Dev Biol. 2023 12; 504:75-85.
Bakis I, Sun Y, Abd Elmagid L, Feng X, Garibyan M, Yip JK, Yu FZ, Chowdhary S, Fernandez GE, Cao J, McCain ML, Lien CL, Harrison MR. PMID: 37708968; PMCID: PMC10841891.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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User-friendly microfluidic system reveals native-like morphological and transcriptomic phenotypes induced by shear stress in proximal tubule epithelium. APL Bioeng. 2023 Sep; 7(3):036106.
Khalil NN, Petersen AP, Song CJ, Chen Y, Takamoto K, Kellogg AC, Chen EZ, McMahon AP, McCain ML. PMID: 37584027; PMCID: PMC10424157.
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PubMed Mentions:
1
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Engineering Programmable Material-To-Cell Pathways Via Synthetic Notch Receptors To Spatially Control Cellular Phenotypes In Multi-Cellular Constructs. bioRxiv. 2023 May 20.
Garibyan M, Hoffman T, Makaske T, Do S, March AR, Cho N, Pedroncelli N, Lima RE, Soto J, Jackson B, Khademhosseini A, Li S, McCain M, Morsut L. PMID: 37293089; PMCID: PMC10245658.
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A myocardial infarct border-zone-on-a-chip demonstrates distinct regulation of cardiac tissue function by an oxygen gradient. Sci Adv. 2022 Dec 09; 8(49):eabn7097.
Rexius-Hall ML, Khalil NN, Escopete SS, Li X, Hu J, Yuan H, Parker SJ, McCain ML. PMID: 36475790; PMCID: PMC9728975.
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PubMed Mentions:
4 Fields:
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Editorial: Modeling neuromuscular diseases to determine molecular drivers of pathology and for drug discovery. Front Cell Dev Biol. 2022; 10:1017356.
Smith AST, McCain ML, Bothwell M, Mack DL. PMID: 36274836; PMCID: PMC9581269.
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PubMed Mentions:
1
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Modeling Patient-Specific Muscular Dystrophy Phenotypes and Therapeutic Responses in Reprogrammed Myotubes Engineered on Micromolded Gelatin Hydrogels. Front Cell Dev Biol. 2022; 10:830415.
Barthélémy F, Santoso JW, Rabichow L, Jin R, Little I, Nelson SF, McCain ML, Miceli MC. PMID: 35465312; PMCID: PMC9020228.
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PubMed Mentions:
3
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Heterogeneous pdgfrb+ cells regulate coronary vessel development and revascularization during heart regeneration. Development. 2022 02 15; 149(4).
Kapuria S, Bai H, Fierros J, Huang Y, Ma F, Yoshida T, Aguayo A, Kok F, Wiens KM, Yip JK, McCain ML, Pellegrini M, Nagashima M, Hitchcock PF, Mochizuki N, Lawson ND, Harrison MMR, Lien CL. PMID: 35088848; PMCID: PMC8918812.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Quantifying Propagation Velocity from Engineered Cardiac Tissues with High-Speed Fluorescence Microscopy and Automated Analysis Software. Methods Mol Biol. 2022; 2485:133-145.
Petersen AP, McCain ML. PMID: 35618903.
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HumansAnimalsCells
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Engineering the Cellular Microenvironment of Post-infarct Myocardium on a Chip. Front Cardiovasc Med. 2021; 8:709871.
Khalil NN, McCain ML. PMID: 34336962; PMCID: PMC8316619.
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PubMed Mentions:
4
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Engineering skeletal muscle tissues with advanced maturity improves synapse formation with human induced pluripotent stem cell-derived motor neurons. APL Bioeng. 2021 Sep; 5(3):036101.
Santoso JW, Li X, Gupta D, Suh GC, Hendricks E, Lin S, Perry S, Ichida JK, Dickman D, McCain ML. PMID: 34286174; PMCID: PMC8282350.
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PubMed Mentions:
10
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Contact photolithography-free integration of patterned and semi-transparent indium tin oxide stimulation electrodes into polydimethylsiloxane-based heart-on-a-chip devices for streamlining physiological recordings. Lab Chip. 2021 02 23; 21(4):674-687.
Yip JK, Sarkar D, Petersen AP, Gipson JN, Tao J, Kale S, Rexius-Hall ML, Cho N, Khalil NN, Kapadia R, McCain ML. PMID: 33439202; PMCID: PMC7968549.
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PubMed Mentions:
3 Fields:
Translation:
Animals
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Tools, techniques, and future opportunities for characterizing the mechanobiology of uterine myometrium. Exp Biol Med (Maywood). 2021 05; 246(9):1025-1035.
Maxey AP, McCain ML. PMID: 33554648; PMCID: PMC8113740.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Characterization of Gelatin Hydrogels Cross-Linked with Microbial Transglutaminase as Engineered Skeletal Muscle Substrates. Bioengineering (Basel). 2021 Jan 06; 8(1).
Gupta D, Santoso JW, McCain ML. PMID: 33418892; PMCID: PMC7825108.
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PubMed Mentions:
20
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Engineering Shape-Controlled Microtissues on Compliant Hydrogels with Tunable Rigidity and Extracellular Matrix Ligands. Methods Mol Biol. 2021; 2258:57-72.
Rexius-Hall ML, Ariyasinghe NR, McCain ML. PMID: 33340354.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Mitochondrial architecture in cardiac myocytes depends on cell shape and matrix rigidity. J Mol Cell Cardiol. 2021 01; 150:32-43.
Lyra-Leite DM, Petersen AP, Ariyasinghe NR, Cho N, McCain ML. PMID: 33038389.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Optical Clearing of Skeletal Muscle Bundles Engineered in 3-D Printed Templates. Ann Biomed Eng. 2021 Feb; 49(2):523-535.
Ariyasinghe NR, Santoso JW, Gupta D, Pincus MJ, August PR, McCain ML. PMID: 32748107.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Mitochondrial division inhibitor 1 (mdivi-1) increases oxidative capacity and contractile stress generated by engineered skeletal muscle. FASEB J. 2020 09; 34(9):11562-11576.
Rexius-Hall ML, Khalil NN, Andres AM, McCain ML. PMID: 32652761.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Neuromuscular disease modeling on a chip. Dis Model Mech. 2020 07 07; 13(7).
Santoso JW, McCain ML. PMID: 32817118; PMCID: PMC7358135.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Regulation of calcium dynamics and propagation velocity by tissue microstructure in engineered strands of cardiac tissue. Integr Biol (Camb). 2020 03 06; 12(2):34-46.
Petersen AP, Cho N, Lyra-Leite DM, Santoso JW, Gupta D, Ariyasinghe NR, McCain ML. PMID: 32118279.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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Extended culture and imaging of normal and regenerating adult zebrafish hearts in a fluidic device. Lab Chip. 2020 01 21; 20(2):274-284.
Yip JK, Harrison M, Villafuerte J, Fernandez GE, Petersen AP, Lien CL, McCain ML. PMID: 31872200; PMCID: PMC8015799.
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PubMed Mentions:
9 Fields:
Translation:
Animals
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Matrix-guided control of mitochondrial function in cardiac myocytes. Acta Biomater. 2019 10 01; 97:281-295.
Lyra-Leite DM, Andres AM, Cho N, Petersen AP, Ariyasinghe NR, Kim SS, Gottlieb RA, McCain ML. PMID: 31401347; PMCID: PMC6801042.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Engineering cardiac microphysiological systems to model pathological extracellular matrix remodeling. Am J Physiol Heart Circ Physiol. 2018 10 01; 315(4):H771-H789.
Ariyasinghe NR, Lyra-Leite DM, McCain ML. PMID: 29906229; PMCID: PMC6230901.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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Microenvironmental Modulation of Calcium Wave Propagation Velocity in Engineered Cardiac Tissues. Cell Mol Bioeng. 2018 Oct; 11(5):337-352.
Petersen AP, Lyra-Leite DM, Ariyasinghe NR, Cho N, Goodwin CM, Kim JY, McCain ML. PMID: 31719889; PMCID: PMC6816715.
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PubMed Mentions:
12
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Featured Article: TGF-β1 dominates extracellular matrix rigidity for inducing differentiation of human cardiac fibroblasts to myofibroblasts. Exp Biol Med (Maywood). 2018 04; 243(7):601-612.
Cho N, Razipour SE, McCain ML. PMID: 29504479; PMCID: PMC6582399.
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PubMed Mentions:
23 Fields:
Translation:
HumansCells
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Engineering micromyocardium to delineate cellular and extracellular regulation of myocardial tissue contractility. Integr Biol (Camb). 2017 09 18; 9(9):730-741.
Ariyasinghe NR, Reck CH, Viscio AA, Petersen AP, Lyra-Leite DM, Cho N, McCain ML. PMID: 28726917.
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PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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Mitochondrial function in engineered cardiac tissues is regulated by extracellular matrix elasticity and tissue alignment. Am J Physiol Heart Circ Physiol. 2017 Oct 01; 313(4):H757-H767.
Lyra-Leite DM, Andres AM, Petersen AP, Ariyasinghe NR, Cho N, Lee JA, Gottlieb RA, McCain ML. PMID: 28733449; PMCID: PMC5668604.
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PubMed Mentions:
29 Fields:
Translation:
AnimalsCells
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Toward improved myocardial maturity in an organ-on-chip platform with immature cardiac myocytes. Exp Biol Med (Maywood). 2017 11; 242(17):1643-1656.
Sheehy SP, Grosberg A, Qin P, Behm DJ, Ferrier JP, Eagleson MA, Nesmith AP, Krull D, Falls JG, Campbell PH, McCain ML, Willette RN, Hu E, Parker KK. PMID: 28343439; PMCID: PMC5786366.
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PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
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Fabrication of Micromolded Gelatin Hydrogels for Long-Term Culture of Aligned Skeletal Myotubes. Methods Mol Biol. 2017; 1668:147-163.
Suh GC, Bettadapur A, Santoso JW, McCain ML. PMID: 28842908.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Prolonged Culture of Aligned Skeletal Myotubes on Micromolded Gelatin Hydrogels. Sci Rep. 2016 06 28; 6:28855.
Bettadapur A, Suh GC, Geisse NA, Wang ER, Hua C, Huber HA, Viscio AA, Kim JY, Strickland JB, McCain ML. PMID: 27350122; PMCID: PMC4924097.
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PubMed Mentions:
64 Fields:
Translation:
AnimalsCells
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Coupling primary and stem cell-derived cardiomyocytes in an in vitro model of cardiac cell therapy. J Cell Biol. 2016 Feb 15; 212(4):389-97.
Aratyn-Schaus Y, Pasqualini FS, Yuan H, McCain ML, Ye GJ, Sheehy SP, Campbell PH, Parker KK. PMID: 26858266; PMCID: PMC4754718.
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PubMed Mentions:
26 Fields:
Translation:
AnimalsCells
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Angiotensin II Induced Cardiac Dysfunction on a Chip. PLoS One. 2016; 11(1):e0146415.
Horton RE, Yadid M, McCain ML, Sheehy SP, Pasqualini FS, Park SJ, Cho A, Campbell P, Parker KK. PMID: 26808388; PMCID: PMC4725954.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Cytoskeletal prestress regulates nuclear shape and stiffness in cardiac myocytes. Exp Biol Med (Maywood). 2015 Nov; 240(11):1543-54.
Lee H, Adams WJ, Alford PW, McCain ML, Feinberg AW, Sheehy SP, Goss JA, Parker KK. PMID: 25908635; PMCID: PMC4778402.
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PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
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Human airway musculature on a chip: an in vitro model of allergic asthmatic bronchoconstriction and bronchodilation. Lab Chip. 2014 Oct 21; 14(20):3925-36.
Nesmith AP, Agarwal A, McCain ML, Parker KK. PMID: 25093641; PMCID: PMC4167568.
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PubMed Mentions:
38 Fields:
Translation:
HumansCells
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Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies. Nat Med. 2014 Jun; 20(6):616-23.
Wang G, McCain ML, Yang L, He A, Pasqualini FS, Agarwal A, Yuan H, Jiang D, Zhang D, Zangi L, Geva J, Roberts AE, Ma Q, Ding J, Chen J, Wang DZ, Li K, Wang J, Wanders RJ, Kulik W, Vaz FM, Laflamme MA, Murry CE, Chien KR, Kelley RI, Church GM, Parker KK, Pu WT. PMID: 24813252; PMCID: PMC4172922.
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PubMed Mentions:
434 Fields:
Translation:
HumansCells
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Engineering cardiac cell junctions in vitro to study the intercalated disc. Cell Commun Adhes. 2014 Jun; 21(3):181-91.
McCain ML, Desplantez T, Kléber AG. PMID: 24754499.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Micromolded gelatin hydrogels for extended culture of engineered cardiac tissues. Biomaterials. 2014 Jul; 35(21):5462-71.
McCain ML, Agarwal A, Nesmith HW, Nesmith AP, Parker KK. PMID: 24731714; PMCID: PMC4057039.
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PubMed Mentions:
82 Fields:
Translation:
AnimalsCells
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Matrix elasticity regulates the optimal cardiac myocyte shape for contractility. Am J Physiol Heart Circ Physiol. 2014 Jun 01; 306(11):H1525-39.
McCain ML, Yuan H, Pasqualini FS, Campbell PH, Parker KK. PMID: 24682394; PMCID: PMC4042196.
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PubMed Mentions:
57 Fields:
Translation:
AnimalsCells
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Microfluidic heart on a chip for higher throughput pharmacological studies. Lab Chip. 2013 Sep 21; 13(18):3599-608.
Agarwal A, Goss JA, Cho A, McCain ML, Parker KK. PMID: 23807141; PMCID: PMC3786400.
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PubMed Mentions:
192 Fields:
Translation:
AnimalsCells
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Micropatterning Alginate Substrates for in vitro Cardiovascular Muscle on a Chip. Adv Funct Mater. 2013 Aug 12; 23(30):3738-3746.
Agarwal A, Farouz Y, Nesmith AP, Deravi LF, McCain ML, Parker KK. PMID: 26213529; PMCID: PMC4511503.
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PubMed Mentions:
45
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Recapitulating maladaptive, multiscale remodeling of failing myocardium on a chip. Proc Natl Acad Sci U S A. 2013 Jun 11; 110(24):9770-5.
McCain ML, Sheehy SP, Grosberg A, Goss JA, Parker KK. PMID: 23716679; PMCID: PMC3683774.
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PubMed Mentions:
72 Fields:
Translation:
HumansAnimalsCells
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A tissue-engineered jellyfish with biomimetic propulsion. Nat Biotechnol. 2012 Aug; 30(8):792-7.
Nawroth JC, Lee H, Feinberg AW, Ripplinger CM, McCain ML, Grosberg A, Dabiri JO, Parker KK. PMID: 22820316; PMCID: PMC4026938.
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PubMed Mentions:
149 Fields:
Translation:
AnimalsCells
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Cooperative coupling of cell-matrix and cell-cell adhesions in cardiac muscle. Proc Natl Acad Sci U S A. 2012 Jun 19; 109(25):9881-6.
McCain ML, Lee H, Aratyn-Schaus Y, Kléber AG, Parker KK. PMID: 22675119; PMCID: PMC3382528.
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PubMed Mentions:
75 Fields:
Translation:
AnimalsCells
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Electrical coupling and propagation in engineered ventricular myocardium with heterogeneous expression of connexin43. Circ Res. 2012 May 25; 110(11):1445-53.
Beauchamp P, Desplantez T, McCain ML, Li W, Asimaki A, Rigoli G, Parker KK, Saffitz JE, Kleber AG. PMID: 22518032; PMCID: PMC3381798.
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PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
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Muscle on a chip: in vitro contractility assays for smooth and striated muscle. J Pharmacol Toxicol Methods. 2012 May-Jun; 65(3):126-35.
Grosberg A, Nesmith AP, Goss JA, Brigham MD, McCain ML, Parker KK. PMID: 22521339; PMCID: PMC4184427.
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PubMed Mentions:
66 Fields:
Translation:
HumansAnimalsCells
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Connexin43 ablation in foetal atrial myocytes decreases electrical coupling, partner connexins, and sodium current. Cardiovasc Res. 2012 Apr 01; 94(1):58-65.
Desplantez T, McCain ML, Beauchamp P, Rigoli G, Rothen-Rutishauser B, Parker KK, Kleber AG. PMID: 22287588; PMCID: PMC3307380.
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PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
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Cell-to-cell coupling in engineered pairs of rat ventricular cardiomyocytes: relation between Cx43 immunofluorescence and intercellular electrical conductance. Am J Physiol Heart Circ Physiol. 2012 Jan; 302(2):H443-50.
McCain ML, Desplantez T, Geisse NA, Rothen-Rutishauser B, Oberer H, Parker KK, Kleber AG. PMID: 22081700; PMCID: PMC3339855.
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PubMed Mentions:
34 Fields:
Translation:
AnimalsCells
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Ensembles of engineered cardiac tissues for physiological and pharmacological study: heart on a chip. Lab Chip. 2011 Dec 21; 11(24):4165-73.
Grosberg A, Alford PW, McCain ML, Parker KK. PMID: 22072288; PMCID: PMC4038963.
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PubMed Mentions:
214 Fields:
Translation:
AnimalsCells
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Mechanotransduction: the role of mechanical stress, myocyte shape, and cytoskeletal architecture on cardiac function. Pflugers Arch. 2011 Jul; 462(1):89-104.
McCain ML, Parker KK. PMID: 21499986.
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PubMed Mentions:
113 Fields:
Translation:
Cells
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Connexin 43 expression delineates two discrete pathways in the human atrioventricular junction. Anat Rec (Hoboken). 2008 Feb; 291(2):204-15.
Hucker WJ, McCain ML, Laughner JI, Iaizzo PA, Efimov IR. PMID: 18085635; PMCID: PMC2756604.
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PubMed Mentions:
33 Fields:
Translation:
HumansCells