Daniel A. Oakes, MD

Title(s)Associate Professor of Clinical Orthopaedic Surgery
SchoolKeck School of Medicine of Usc
AddressHC2 - 1520 San Pablo Street, #2000
Health Sciences Campus
Los Angeles CA 90033
Phone+1 323 442 6950
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    Collapse Biography 
    Collapse Awards and Honors
    Pasadena Magazine2010  - 2019Top Doctor
    Los Angeles Magazine2016  - 2022Super Doctor
    Castle Connolly2014  - 2020America's Top Doctors
    Los Angeles Magazine2018Top Doctors
    USC2011Residency Faculty Teaching Award
    USC2018Residency Faculty Teaching Award
    American Orthopaedic Society for Sports Medicine 2002Excellence in Research Award
    Mayo Clinic2004Mark B. Coventry Adult Reconstruction Fellowship Award

    Collapse Overview 
    Collapse Overview
    Dr. Oakes is an Associate Professor in the Department of Orthopaedic Surgery at the Keck School of Medicine of USC and the Director of the USC Joint Replacement Program.

    Dr. Oakes is nationally recognized for his expertise in knee and hip replacement and reconstruction. He has extensive experience with both primary and revision of hip and knee replacement procedures. Dr. Oakes is actively engaged in the role of emerging computer assisted navigation technologies for hip and knee joint replacement procedures and robotic surgery for full and partial knee replacement. Dr. Oakes performed the first robotic total knee surgery at Keck Medical Center of USC in 2018.

    Dr. Oakes is interested in the technology advances that improve the longevity implants and patient outcomes. He and his team have worked to develop strategies both to prevent and treat infected joint replacements. His active research focuses on the long-term outcomes of robotic partial and total knee replacement outcomes, of porous metal technology in complex primary and complex revision improving longevity of implant technologies and the prevention and treatment of infected joint replacements, of porous metal technology in complex revision knee replacements, of single stage treatments for infection and of hip resurfacing as an alternative to joint replacement.

    Dr. Oakes has consistently been voted a Top Doctor by Pasadena Magazine, Super Doctor by Los Angeles Magazine, and one of America’s Top Doctors by Castle Connolly. He is a fellow in the American Academy of Orthopaedic Surgeons (AAOS). He is a member of the American Association of Hip and Knee Surgeons(AAHKS) and has served as chair of its membership committee.

    Dr. Oakes received his medical degree from Harvard Medical School and completed his fellowship training at the Mayo Clinic, where he received the Mark B. Coventry Adult Reconstruction Fellowship Award.

    Dr. Oakes is both the Residency Program Director and the Joint Replacement fellowship director. He has twice been the recipient of the departments award for teaching excellence.

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Refining the Role of Routine Synovial Alpha-Defensin in Periprosthetic Joint Infection Following Total Knee Arthroplasty: An Analysis of Limitations. J Arthroplasty. 2023 Jun 08. Heckmann ND, Wang JC, Liu KC, Won P, Chung BC, Mayer LW, Longjohn DB, Oakes DA, Christ AB, Lieberman JR. PMID: 37295619.
      View in: PubMed   Mentions:    Fields:    
    2. Factors Associated With Failure Following Proximal Femoral Replacement for Salvage Hip Surgery for Nononcologic Indications. J Arthroplasty. 2023 May 19. Wier J, Liu KC, Piple AS, Christ AB, Longjohn DB, Oakes DA, Heckmann ND. PMID: 37209911.
      View in: PubMed   Mentions:    Fields:    
    3. Positive COVID-19 Diagnosis Following Primary Elective Total Joint Arthroplasty: Increased Complication and Mortality Rates. J Arthroplasty. 2023 May 02. Heckmann ND, Wang JC, Piple AS, Bouz GJ, Chung BC, Oakes DA, Christ AB, Lieberman JR. PMID: 37142066; PMCID: PMC10151250.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. A double-blinded, placebo-controlled, randomized study to evaluate the efficacy of perioperative dextromethorphan compared to placebo for the treatment of postoperative pain: a study protocol. Trials. 2023 Mar 29; 24(1):238. Jones IA, Piple AS, Yan PY, Longjohn DB, Gilbert PK, Lieberman JR, Gucev GV, Oakes DA, Ratto CE, Christ AB, Heckmann ND. PMID: 36991450; PMCID: PMC10061841.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    5. Aspirin for Venous Thromboembolic Prophylaxis Following Total Hip and Total Knee Arthroplasty: An Analysis of Safety and Efficacy Accounting for Surgeon Selection Bias. J Arthroplasty. 2023 Mar 03. Heckmann ND, Piple AS, Wang JC, Richardson MK, Mayfield CK, Oakes DA, Christ AB, Lieberman JR. PMID: 36870517.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Drill Bone with Both Hands: Plunge Depth and Accuracy with 4 Bracing Positions. JB JS Open Access. 2023 Jan-Mar; 8(1). Patterson JT, Becerra JA, Duong A, Reddy A, Oakes DA. PMID: 36873137; PMCID: PMC9977482.
      View in: PubMed   Mentions:
    7. Peripheral Nerve Block Utilization is Associated With Decreased Postoperative Opioid Consumption and Shorter Length of Stay Following Total Knee Arthroplasty. Arthroplast Today. 2023 Apr; 20:101101. Wang JC, Piple AS, Mayfield CK, Chung BC, Oakes DA, Gucev G, Lieberman JR, Christ AB, Heckmann ND. PMID: 36891161; PMCID: PMC9988417.
      View in: PubMed   Mentions: 1  
    8. The Persistent Effects of the COVID-19 Pandemic on Total Joint Arthroplasty Changes in Practice Patterns in the United States From 2020 to 2021. J Arthroplasty. 2023 08; 38(8):1438-1443.e1. Piple AS, Wang JC, Bouz GJ, Chung BC, Mayfield CK, Richardson MK, Oakes DA, Lieberman JR, Christ AB, Heckmann ND. PMID: 36754335; PMCID: PMC9902285.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsPHPublic Health
    9. Does Prednisone Dose Affect Rates of Periprosthetic Joint Infection Following Primary Total Hip and Total Knee Arthroplasty? J Arthroplasty. 2023 06; 38(6):1024-1031. Piple AS, Wang JC, Kebaish KJ, Mills ES, Oakes DA, Lieberman JR, Christ AB, Heckmann ND. PMID: 36566997.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Influence of donor age and comorbidities on transduced human adipose-derived stem cell in vitro osteogenic potential. Gene Ther. 2023 04; 30(3-4):369-376. Collon K, Bell JA, Gallo MC, Chang SW, Bougioukli S, Sugiyama O, Tassey J, Hollis R, Heckmann N, Oakes DA, Longjohn DB, Evseenko D, Kohn DB, Lieberman JR. PMID: 36216880; PMCID: PMC10086075.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    11. Tranexamic Acid and Prothrombotic Complications Following Total Hip and Total Knee Arthroplasty: A Population-Wide Safety Analysis Accounting for Surgeon Selection Bias. J Arthroplasty. 2023 02; 38(2):215-223. Heckmann ND, Haque TF, Piple AS, Mayfield CK, Bouz GJ, Mayer LW, Oakes DA, Lieberman JR, Christ AB. PMID: 36007755.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Monomicrobial Joint Infection by Leclercia adecarboxylata in an Immunocompetent Patient After Knee Arthroscopy: A Case Report. JBJS Case Connect. 2022 07 01; 12(3). Householder NA, Harris CS, Kugler KM, Oakes DA, Powell SE. PMID: 35833641.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    13. Systematic Review and Meta-Analysis of Intrawound Vancomycin in Total Hip and Total Knee Arthroplasty: A Continued Call for a Prospective Randomized Trial. J Arthroplasty. 2022 07; 37(7):1405-1415.e1. Movassaghi K, Wang JC, Gettleman BS, Mayfield CK, Oakes DA, Lieberman JR, Heckmann ND. PMID: 35314283.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    14. Elective Inpatient Total Joint Arthroplasty Case Volume in the United States in 2020: Effects of the COVID-19 Pandemic. J Bone Joint Surg Am. 2022 07 06; 104(13):e56. Heckmann ND, Bouz GJ, Piple AS, Chung BC, Wang JC, Mayfield CK, Stambough JB, Oakes DA, Christ AB, Lieberman JR. PMID: 35275853.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    15. Modern Proximal Femoral Replacement in Revision Total Hip Arthroplasty for Nononcologic Indications. J Arthroplasty. 2022 08; 37(8S):S958-S963. Heckmann ND, Nakata HL, Chung BC, Baker JR, Longjohn DB, Christ AB, Oakes DA. PMID: 35189288.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. Utilization of technology-assisted total hip arthroplasty in the United States from 2005 to 2018. Arthroplast Today. 2021 Dec; 12:36-44. Korber S, Antonios JK, Sivasundaram L, Mayfield CK, Kang HP, Chung BC, Oakes DA, Heckmann ND. PMID: 34761092; PMCID: PMC8567325.
      View in: PubMed   Mentions:
    17. Regional Gene Therapy with Transduced Human Cells: The Influence of "Cell Dose" on Bone Repair. Tissue Eng Part A. 2021 11; 27(21-22):1422-1433. Ihn H, Kang H, Iglesias B, Sugiyama O, Tang A, Hollis R, Bougioukli S, Skorka T, Park S, Longjohn D, Oakes DA, Kohn DB, Lieberman JR. PMID: 33882718; PMCID: PMC8827114.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    18. Dose-Dependent Early Postoperative Opioid Use Is Associated with Periprosthetic Joint Infection and Other Complications in Primary TJA. J Bone Joint Surg Am. 2021 08 18; 103(16):1531-1542. Chung BC, Bouz GJ, Mayfield CK, Nakata H, Christ AB, Oakes DA, Lieberman JR, Heckmann ND. PMID: 34043598.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    19. Patient Perception Regarding the Safety of Elective Joint Arthroplasty Surgery During the COVID-19 Pandemic. Arthroplast Today. 2021 Oct; 11:113-121. Chen XT, Chung BC, Jones IA, Christ AB, Oakes DA, Gilbert PK, Longjohn DB, Lieberman JR, Heckmann ND. PMID: 34493982; PMCID: PMC8414990.
      View in: PubMed   Mentions: 1  
    20. Regional gene therapy for bone healing using a 3D printed scaffold in a rat femoral defect model. J Biomed Mater Res A. 2021 11; 109(11):2346-2356. Kang HP, Ihn H, Robertson DM, Chen X, Sugiyama O, Tang A, Hollis R, Skorka T, Longjohn D, Oakes D, Shah R, Kohn D, Jakus AE, Lieberman JR. PMID: 34018305.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    21. Population-based Survivorship of Computer-navigated Versus Conventional Total Knee Arthroplasty. J Am Acad Orthop Surg. 2020 Oct 15; 28(20):857-864. Antonios JK, Kang HP, Robertson D, Oakes DA, Lieberman JR, Heckmann ND. PMID: 31934926.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    22. Limited potential of AAV-mediated gene therapy in transducing human mesenchymal stem cells for bone repair applications. Gene Ther. 2021 12; 28(12):729-739. Bougioukli S, Chateau M, Morales H, Vakhshori V, Sugiyama O, Oakes D, Longjohn D, Cannon P, Lieberman JR. PMID: 32807899.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    23. Ex vivo gene therapy using human bone marrow cells overexpressing BMP-2: "Next-day" gene therapy versus standard "two-step" approach. Bone. 2019 11; 128:115032. Bougioukli S, Alluri R, Pannell W, Sugiyama O, Vega A, Tang A, Skorka T, Park SH, Oakes D, Lieberman JR. PMID: 31398502; PMCID: PMC6813891.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    24. Systematic Review and Meta-Analysis of Intrawound Vancomycin in Total Hip and Total Knee Arthroplasty: A Call for a Prospective Randomized Trial. J Arthroplasty. 2019 Aug; 34(8):1815-1822. Heckmann ND, Mayfield CK, Culvern CN, Oakes DA, Lieberman JR, Della Valle CJ. PMID: 31005433.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    25. Trends in computer navigation and robotic assistance for total knee arthroplasty in the United States: an analysis of patient and hospital factors. Arthroplast Today. 2019 Mar; 5(1):88-95. Antonios JK, Korber S, Sivasundaram L, Mayfield C, Kang HP, Oakes DA, Heckmann ND. PMID: 31020030; PMCID: PMC6470347.
      View in: PubMed   Mentions: 34  
    26. Complex Reconstruction of the Knee with a Free Vertical Rectus Abdominis Flap after Periprosthetic Soft Tissue Necrosis. Cureus. 2019 Jan 28; 11(1):e3969. Perrault D, Manrique OJ, Lee G, Carre AL, Oakes DA, Wong AK. PMID: 30956921; PMCID: PMC6438685.
      View in: PubMed   Mentions: 1  
    27. In vitro evaluation of a lentiviral two-step transcriptional amplification system using GAL4FF transactivator for gene therapy applications in bone repair. Gene Ther. 2018 07; 25(4):260-268. Bougioukli S, Sugiyama O, Alluri RK, Yoho R, Oakes DA, Lieberman JR. PMID: 29907876.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    28. Gene Therapy for Bone Repair Using Human Cells: Superior Osteogenic Potential of Bone Morphogenetic Protein 2-Transduced Mesenchymal Stem Cells Derived from Adipose Tissue Compared to Bone Marrow. Hum Gene Ther. 2018 04; 29(4):507-519. Bougioukli S, Sugiyama O, Pannell W, Ortega B, Tan MH, Tang AH, Yoho R, Oakes DA, Lieberman JR. PMID: 29212377; PMCID: PMC5909082.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    29. The Cost of Getting Into Orthopedic Residency: Analysis of Applicant Demographics, Expenditures, and the Value of Away Rotations. J Surg Educ. 2016 Sep-Oct; 73(5):886-91. Camp CL, Sousa PL, Hanssen AD, Karam MD, Haidukewych GJ, Oakes DA, Turner NS. PMID: 27184179.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    30. Orthopedic Surgery Applicants: What They Want in an Interview and How They Are Influenced by Post-Interview Contact. J Surg Educ. 2016 Jul-Aug; 73(4):709-14. Camp CL, Sousa PL, Hanssen AD, Karam MD, Haidukewych GJ, Oakes DA, Turner NS. PMID: 27137662.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    31. Effect of proximal femoral bone support on the fixation of a press-fit noncemented total hip replacement femoral component. J Appl Biomater Funct Mater. 2013 Jun 24; 11(1):e26-34. Sangiorgio SN, Ebramzadeh E, Borkowski SL, Oakes DA, Reid JJ, Bengs BC. PMID: 23413131.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    32. Disappointing short-term results with the DePuy ASR XL metal-on-metal total hip arthroplasty. J Arthroplasty. 2012 Apr; 27(4):539-44. Bernthal NM, Celestre PC, Stavrakis AI, Ludington JC, Oakes DA. PMID: 22000575.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansPHPublic Health
    33. How long do endoprosthetic reconstructions for proximal femoral tumors last? Clin Orthop Relat Res. 2010 Nov; 468(11):2867-74. Bernthal NM, Schwartz AJ, Oakes DA, Kabo JM, Eckardt JJ. PMID: 20440661; PMCID: PMC2947672.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    34. Acetabular morphology in bladder exstrophy complex. Clin Orthop Relat Res. 2007 May; 458:125-30. Nehme A, Oakes D, Perry MJ, Hawatmeh SI, Trousdale RT. PMID: 17308482.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    35. Impaction bone grafting for revision hip arthroplasty: biology and clinical applications. J Am Acad Orthop Surg. 2006 Oct; 14(11):620-8. Oakes DA, Cabanela ME. PMID: 17030595.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    36. Magnetic resonance imaging with metal suppression for evaluation of periprosthetic osteolysis after total knee arthroplasty. J Arthroplasty. 2006 Sep; 21(6):826-31. Vessely MB, Frick MA, Oakes D, Wenger DE, Berry DJ. PMID: 16950034.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    37. Safety of rasagiline in elderly patients with Parkinson disease. Neurology. 2006 May 09; 66(9):1427-9. Goetz CG, Schwid SR, Eberly SW, Oakes D, Shoulson I, Parkinson Study Group TEMPO and PRESTO Investigators. PMID: 16682679.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    38. Persistent bladder entrapment following acetabular fracture with subsequent vesical injury during total hip arthroplasty. A case report. J Bone Joint Surg Am. 2005 Apr; 87(4):870-3. Nehme A, Maalouf G, Oakes D, Ghantous I, Trousdale RT. PMID: 15805219.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    39. Compressive intrapelvic synovial cysts: an early complication of an HA-coated cup. Clin Orthop Relat Res. 2005 Jan; (430):232-6. Nehme A, Oakes DA, Marcheix B, Gomez-Brouchet A, Puget J. PMID: 15662329.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    40. Bilateral total knee replacement using the same anesthetic is not justified by assessment of the risks. Clin Orthop Relat Res. 2004 Nov; (428):87-91. Oakes DA, Hanssen AD. PMID: 15534525.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    41. The effect of femoral tunnel position on graft forces during inlay posterior cruciate ligament reconstruction. Am J Sports Med. 2003 Sep-Oct; 31(5):667-72. Oakes DA, Markolf KL, McWilliams J, Young CR, McAllister DR. PMID: 12975184.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    42. An evaluation of human demineralized bone matrices in a rat femoral defect model. Clin Orthop Relat Res. 2003 Aug; (413):281-90. Oakes DA, Lee CC, Lieberman JR. PMID: 12897620.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimals
    43. Failure of heat shrinkage for treatment of a posterior cruciate ligament tear. Arthroscopy. 2003 Jul-Aug; 19(6):E1-4. Oakes DA, McAllister DR. PMID: 12861215.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    44. The impact of the garden classification on proposed operative treatment. Clin Orthop Relat Res. 2003 Apr; (409):232-40. Oakes DA, Jackson KR, Davies MR, Ehrhart KM, Zohman GL, Koval KJ, Lieberman JR. PMID: 12671507.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    45. Effects of notchplasty and femoral tunnel position on excursion patterns of an anterior cruciate ligament graft. Arthroscopy. 2003 Apr; 19(4):340-5. Hame SL, Markolf KL, Hunter DM, Oakes DA, Zoric B. PMID: 12671615.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    46. Biomechanical effects of medial-lateral tibial tunnel placement in posterior cruciate ligament reconstruction. J Orthop Res. 2003 Jan; 21(1):177-82. Markolf KL, McAllister DR, Young CR, McWilliams J, Oakes DA. PMID: 12507596.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    47. Injury to the anterior cruciate ligament during alpine skiing: a biomechanical analysis of tibial torque and knee flexion angle. Am J Sports Med. 2002 Jul-Aug; 30(4):537-40. Hame SL, Oakes DA, Markolf KL. PMID: 12130408.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    48. A biomechanical comparison of tibial inlay and tibial tunnel posterior cruciate ligament reconstruction techniques: graft pretension and knee laxity. Am J Sports Med. 2002 May-Jun; 30(3):312-7. McAllister DR, Markolf KL, Oakes DA, Young CR, McWilliams J. PMID: 12016068.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    49. Biomechanical effects of femoral notchplasty in anterior cruciate ligament reconstruction. Am J Sports Med. 2002 Jan-Feb; 30(1):83-9. Markolf KL, Hame SL, Hunter DM, Oakes D, Gause P. PMID: 11799001.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    50. An atypical appearance of a posterior dislocation of the shoulder with a fracture of the proximal humerus. J Shoulder Elbow Surg. 2001 Mar-Apr; 10(2):182-5. Oakes DA, McAllister DR. PMID: 11307083.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    51. Osteoinductive applications of regional gene therapy: ex vivo gene transfer. Clin Orthop Relat Res. 2000 Oct; (379 Suppl):S101-12. Oakes DA, Lieberman JR. PMID: 11039758.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    52. Covering the "open abdomen": a better technique. Am Surg. 1998 Sep; 64(9):854-7. Sherck J, Seiver A, Shatney C, Oakes D, Cobb L. PMID: 9731813.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    53. Development of a risk assessment for BSE in the aquatic environment. J Appl Microbiol. 1998 Apr; 84(4):467-77. Gale P, Young C, Stanfield G, Oakes D. PMID: 9633645.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    54. A randomized, double-blind, placebo-controlled trial of systemically administered interferon-alpha, -beta, or -gamma in combination with cryotherapy for the treatment of condyloma acuminatum. J Infect Dis. 1995 May; 171(5):1081-9. Bonnez W, Oakes D, Bailey-Farchione A, Choi A, Hallahan D, Pappas P, Holloway M, Corey L, Barnum G, Dunne A, et al. PMID: 7538546.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials