Prasad C. Tongaonkar, PhD

Title(s)Associate Professor of Research Pathology
SchoolKeck School of Medicine of Usc
AddressNRT 1450 Biggy St
Health Sciences Campus
Los Angeles CA 90089-9601
Phone+1 323 442 7960
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    Post-translational processing of myeloid alpha-defensins.
    NIH R56AI078321Aug 15, 2010 - Jul 31, 2013
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Inhibition of miR-146a Expression and Regulation of Endotoxin Tolerance by Rhesus Theta-Defensin-1. Mediators Inflamm. 2023; 2023:8387330. Tongaonkar P, Trinh KK, Ouellette AJ, Selsted ME. PMID: 37101596; PMCID: PMC10125762.
      View in: PubMed   Mentions: 2     Fields:    
    2. RTD-1 therapeutically normalizes synovial gene signatures in rat autoimmune arthritis and suppresses proinflammatory mediators in RA synovial fibroblasts. Physiol Genomics. 2019 12 01; 51(12):657-667. Tongaonkar P, Punj V, Subramanian A, Tran DQ, Trinh KK, Schaal JB, Laragione T, Ouellette AJ, Gulko PS, Selsted ME. PMID: 31762409; PMCID: PMC6962595.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    3. Fungicidal Potency and Mechanisms of θ-Defensins against Multidrug-Resistant Candida Species. Antimicrob Agents Chemother. 2018 06; 62(6). Basso V, Garcia A, Tran DQ, Schaal JB, Tran P, Ngole D, Aqeel Y, Tongaonkar P, Ouellette AJ, Selsted ME. PMID: 29610196; PMCID: PMC5971616.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    4. Macrocyclic θ-defensins suppress tumor necrosis factor-α (TNF-α) shedding by inhibition of TNF-α-converting enzyme. J Biol Chem. 2018 02 23; 293(8):2725-2734. Schaal JB, Maretzky T, Tran DQ, Tran PA, Tongaonkar P, Blobel CP, Ouellette AJ, Selsted ME. PMID: 29317500; PMCID: PMC5827436.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    5. Suppression and resolution of autoimmune arthritis by rhesus θ-defensin-1, an immunomodulatory macrocyclic peptide. PLoS One. 2017; 12(11):e0187868. Schaal JB, Tran DQ, Subramanian A, Patel R, Laragione T, Roberts KD, Trinh K, Tongaonkar P, Tran PA, Minond D, Fields GB, Beringer P, Ouellette AJ, Gulko PS, Selsted ME. PMID: 29145473; PMCID: PMC5690597.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    6. Rhesus macaque θ-defensin RTD-1 inhibits proinflammatory cytokine secretion and gene expression by inhibiting the activation of NF-κB and MAPK pathways. J Leukoc Biol. 2015 Dec; 98(6):1061-70. Tongaonkar P, Trinh KK, Schaal JB, Tran D, Gulko PS, Ouellette AJ, Selsted ME. PMID: 26269197; PMCID: PMC4661038.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    7. Rhesus macaque theta defensins suppress inflammatory cytokines and enhance survival in mouse models of bacteremic sepsis. PLoS One. 2012; 7(12):e51337. Schaal JB, Tran D, Tran P, Ösapay G, Trinh K, Roberts KD, Brasky KM, Tongaonkar P, Ouellette AJ, Selsted ME. PMID: 23236475; PMCID: PMC3516535.
      View in: PubMed   Mentions: 40     Fields:    Translation:Animals
    8. High fidelity processing and activation of the human α-defensin HNP1 precursor by neutrophil elastase and proteinase 3. PLoS One. 2012; 7(3):e32469. Tongaonkar P, Golji AE, Tran P, Ouellette AJ, Selsted ME. PMID: 22448222; PMCID: PMC3308943.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    9. Rhesus macaque θ-defensin isoforms: expression, antimicrobial activities, and demonstration of a prominent role in neutrophil granule microbicidal activities. J Leukoc Biol. 2011 Feb; 89(2):283-90. Tongaonkar P, Tran P, Roberts K, Schaal J, Osapay G, Tran D, Ouellette AJ, Selsted ME. PMID: 21084627; PMCID: PMC3024902.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    10. SDF2L1, a component of the endoplasmic reticulum chaperone complex, differentially interacts with {alpha}-, {beta}-, and {theta}-defensin propeptides. J Biol Chem. 2009 Feb 27; 284(9):5602-9. Tongaonkar P, Selsted ME. PMID: 19109254; PMCID: PMC2645818.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    11. Transcription of multiple yeast ribosomal DNA genes requires targeting of UAF to the promoter by Uaf30. Mol Cell Biol. 2008 Nov; 28(21):6709-19. Hontz RD, French SL, Oakes ML, Tongaonkar P, Nomura M, Beyer AL, Smith JS. PMID: 18765638; PMCID: PMC2573240.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    12. Histones are required for transcription of yeast rRNA genes by RNA polymerase I. Proc Natl Acad Sci U S A. 2005 Jul 19; 102(29):10129-34. Tongaonkar P, French SL, Oakes ML, Vu L, Schneider DA, Beyer AL, Nomura M. PMID: 16002464; PMCID: PMC1177414.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    13. Rad23 stabilizes Rad4 from degradation by the Ub/proteasome pathway. Nucleic Acids Res. 2004; 32(22):6490-500. Ortolan TG, Chen L, Tongaonkar P, Madura K. PMID: 15601997; PMCID: PMC545455.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    14. SIR2 regulates recombination between different rDNA repeats, but not recombination within individual rRNA genes in yeast. Cell. 2004 May 14; 117(4):441-53. Kobayashi T, Horiuchi T, Tongaonkar P, Vu L, Nomura M. PMID: 15137938.
      View in: PubMed   Mentions: 135     Fields:    Translation:AnimalsCells
    15. Purification and assay of upstream activation factor, core factor, Rrn3p, and yeast RNA polymerase I. Methods Enzymol. 2003; 370:109-20. Tongaonkar P, Dodd JA, Nomura M. PMID: 14712638.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    16. Evidence for separable functions of Srp1p, the yeast homolog of importin alpha (Karyopherin alpha): role for Srp1p and Sts1p in protein degradation. Mol Cell Biol. 2000 Aug; 20(16):6062-73. Tabb MM, Tongaonkar P, Vu L, Nomura M. PMID: 10913188; PMCID: PMC86082.
      View in: PubMed   Mentions: 34     Fields:    Translation:Animals
    17. Evidence for an interaction between ubiquitin-conjugating enzymes and the 26S proteasome. Mol Cell Biol. 2000 Jul; 20(13):4691-8. Tongaonkar P, Chen L, Lambertson D, Ko B, Madura K. PMID: 10848595; PMCID: PMC85887.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    18. Characterization of a temperature-sensitive mutant of a ubiquitin-conjugating enzyme and its use as a heat-inducible degradation signal. Anal Biochem. 1999 Aug 01; 272(2):263-9. Tongaonkar P, Beck K, Shinde UP, Madura K. PMID: 10415098.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    19. Reconstituting ubiquitination reactions with affinity-purified components and 32P-ubiquitin. Anal Biochem. 1998 Jul 01; 260(2):135-41. Tongaonkar P, Madura K. PMID: 9657869.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    20. Sequence elements that contribute to the degradation of yeast G alpha. Genes Cells. 1998 May; 3(5):307-19. Schauber C, Chen L, Tongaonkar P, Vega I, Madura K. PMID: 9685182.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    21. Rad23 links DNA repair to the ubiquitin/proteasome pathway. Nature. 1998 Feb 12; 391(6668):715-8. Schauber C, Chen L, Tongaonkar P, Vega I, Lambertson D, Potts W, Madura K. PMID: 9490418.
      View in: PubMed   Mentions: 161     Fields:    Translation:HumansAnimalsCells
    22. A semi-empirical method for prediction of antigenic determinants on protein antigens. FEBS Lett. 1990 Dec 10; 276(1-2):172-4. Kolaskar AS, Tongaonkar PC. PMID: 1702393.
      View in: PubMed   Mentions: 521     Fields:    Translation:HumansAnimalsCells
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