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Michael E. Selsted, MD, PhD

Title(s)Chair and Professor of Pathology
AddressHMR 2011 Zonal Ave
Health Sciences Campus
Los Angeles CA 90089-9092
Phone+1 323 442 1180
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    Dr. Selsted is an internationally renowned scholar in the field of innate immunity and pathogenesis whose research discoveries have resulted in more than 20 U.S. patents. In addition to his pioneering research and clinical science, Dr. Selsted is a prolific author and experienced administrator. Under his leadership, National Institutes of Health and total research funding at the University of California, Irvine Department of Pathology and Laboratory Medicine increased more than four-fold to $6.6 million.

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    Host defense-stimulating macrocyclic peptides for treatment of MDR bacterial infections
    NIH/NIAID R01AI125141May 1, 2016 - Apr 30, 2021
    Role: Principal Investigator
    Regulation of Mucosal Immunity by Pro- and Anti-inflammatory Salivary Defensins
    NIH/NIDCR R01DE021341Aug 12, 2010 - May 31, 2015
    Role: Principal Investigator
    Physiologic Peptide Cyclization in Myeloid Cells
    NIH/NIAID R01AI058129Jun 1, 2004 - May 31, 2009
    Role: Principal Investigator
    Molecular Ontogeny of Oral Mucosal Resistance to SIV
    NIH/NIDCR R01DE015517Dec 15, 2003 - Nov 30, 2009
    Role: Principal Investigator
    DRUG DISCOVERY FOR TREATMENT OF CRYPTOCOCCAL DISEASE
    NIH/NIAID U01AI031696Aug 1, 1991 - Jul 31, 1995
    Role: Principal Investigator
    MOLECULAR ASPECTS OF LEUKOCYTE ANTIMICROBIAL PEPTIDES
    NIH/NIAID R37AI022931Jul 1, 1989 - Mar 31, 2012
    Role: Principal Investigator
    Molecular Aspects of Leukocyte Antimicrobial Peptides
    NIH/NIAID R01AI022931Jul 1, 1986 - Oct 31, 1989
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. RTD-1 therapeutically normalizes synovial gene signatures in rat autoimmune arthritis and suppresses proinflammatory mediators in RA synovial fibroblasts. Physiol Genomics. 2019 12 01; 51(12):657-667. Tongaonkar P, Punj V, Subramanian A, Tran DQ, Trinh KK, Schaal JB, Laragione T, Ouellette AJ, Gulko PS, Selsted ME. PMID: 31762409.
      View in: PubMed   Mentions:    Fields:    
    2. Rhesus Theta Defensin 1 Promotes Long Term Survival in Systemic Candidiasis by Host Directed Mechanisms. Sci Rep. 2019 11 15; 9(1):16905. Basso V, Tran DQ, Schaal JB, Tran P, Eriguchi Y, Ngole D, Cabebe AE, Park AY, Beringer PM, Ouellette AJ, Selsted ME. PMID: 31729441.
      View in: PubMed   Mentions:    Fields:    
    3. Essential role of IFN-? in T cell-associated intestinal inflammation. JCI Insight. 2018 09 20; 3(18). Eriguchi Y, Nakamura K, Yokoi Y, Sugimoto R, Takahashi S, Hashimoto D, Teshima T, Ayabe T, Selsted ME, Ouellette AJ. PMID: 30232288.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    4. Fungicidal Potency and Mechanisms of ?-Defensins against Multidrug-Resistant Candida Species. Antimicrob Agents Chemother. 2018 06; 62(6). Basso V, Garcia A, Tran DQ, Schaal JB, Tran P, Ngole D, Aqeel Y, Tongaonkar P, Ouellette AJ, Selsted ME. PMID: 29610196.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    5. Rhesus ?-Defensin-1 Attenuates Endotoxin-induced Acute Lung Injury by Inhibiting Proinflammatory Cytokines and Neutrophil Recruitment. Am J Respir Cell Mol Biol. 2018 03; 58(3):310-319. Jayne JG, Bensman TJ, Schaal JB, Park AYJ, Kimura E, Tran D, Selsted ME, Beringer PM. PMID: 28954201.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    6. Macrocyclic ?-defensins suppress tumor necrosis factor-a (TNF-a) shedding by inhibition of TNF-a-converting enzyme. J Biol Chem. 2018 02 23; 293(8):2725-2734. Schaal JB, Maretzky T, Tran DQ, Tran PA, Tongaonkar P, Blobel CP, Ouellette AJ, Selsted ME. PMID: 29317500.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    7. Suppression and resolution of autoimmune arthritis by rhesus ?-defensin-1, an immunomodulatory macrocyclic peptide. PLoS One. 2017; 12(11):e0187868. Schaal JB, Tran DQ, Subramanian A, Patel R, Laragione T, Roberts KD, Trinh K, Tongaonkar P, Tran PA, Minond D, Fields GB, Beringer P, Ouellette AJ, Gulko PS, Selsted ME. PMID: 29145473.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    8. Efficacy of Rhesus Theta-Defensin-1 in Experimental Models of Pseudomonas aeruginosa Lung Infection and Inflammation. Antimicrob Agents Chemother. 2017 08; 61(8). Bensman TJ, Jayne JG, Sun M, Kimura E, Meinert J, Wang JC, Schaal JB, Tran D, Rao AP, Akbari O, Selsted ME, Beringer PM. PMID: 28559270.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    9. Rhesus ?-defensin-1 (RTD-1) exhibits in vitro and in vivo activity against cystic fibrosis strains of Pseudomonas aeruginosa. J Antimicrob Chemother. 2016 Jan; 71(1):181-8. Beringer PM, Bensman TJ, Ho H, Agnello M, Denovel N, Nguyen A, Wong-Beringer A, She R, Tran DQ, Moskowitz SM, Selsted ME. PMID: 26433781.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    10. Rhesus macaque ?-defensin RTD-1 inhibits proinflammatory cytokine secretion and gene expression by inhibiting the activation of NF-?B and MAPK pathways. J Leukoc Biol. 2015 Dec; 98(6):1061-70. Tongaonkar P, Trinh KK, Schaal JB, Tran D, Gulko PS, Ouellette AJ, Selsted ME. PMID: 26269197.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    11. ?-Defensin RTD-1 improves insulin action and normalizes plasma glucose and FFA levels in diet-induced obese rats. Am J Physiol Endocrinol Metab. 2015 Jul 15; 309(2):E154-60. Oh YT, Tran D, Buchanan TA, Selsted ME, Youn JH. PMID: 25991648.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    12. Hydrophobic determinants of a-defensin bactericidal activity. Infect Immun. 2014 Jun; 82(6):2195-202. Tai KP, Le VV, Selsted ME, Ouellette AJ. PMID: 24614658.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    13. Differential Susceptibility of Bacteria to Mouse Paneth Cell a-Defensins under Anaerobic Conditions. Antibiotics (Basel). 2014; 3(4):493-508. Mastroianni JR, Lu W, Selsted ME, Ouellette AJ. PMID: 25383215.
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    14. Killing of staphylococci by ?-defensins involves membrane impairment and activation of autolytic enzymes. Antibiotics (Basel). 2014; 3(4):617-31. Wilmes M, Stockem M, Bierbaum G, Schlag M, Götz F, Tran DQ, Schaal JB, Ouellette AJ, Selsted ME, Sahl HG. PMID: 25632351.
      View in: PubMed   Mentions:
    15. Microbicidal effects of a- and ?-defensins against antibiotic-resistant Staphylococcus aureus and Pseudomonas aeruginosa. Innate Immun. 2015 Jan; 21(1):17-29. Tai KP, Kamdar K, Yamaki J, Le VV, Tran D, Tran P, Selsted ME, Ouellette AJ, Wong-Beringer A. PMID: 24345876.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    16. Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. Nat Prod Rep. 2013 Jan; 30(1):108-60. Arnison PG, Bibb MJ, Bierbaum G, Bowers AA, Bugni TS, Bulaj G, Camarero JA, Campopiano DJ, Challis GL, Clardy J, Cotter PD, Craik DJ, Dawson M, Dittmann E, Donadio S, Dorrestein PC, Entian KD, Fischbach MA, Garavelli JS, Göransson U, Gruber CW, Haft DH, Hemscheidt TK, Hertweck C, Hill C, Horswill AR, Jaspars M, Kelly WL, Klinman JP, Kuipers OP, Link AJ, Liu W, Marahiel MA, Mitchell DA, Moll GN, Moore BS, Müller R, Nair SK, Nes IF, Norris GE, Olivera BM, Onaka H, Patchett ML, Piel J, Reaney MJ, Rebuffat S, Ross RP, Sahl HG, Schmidt EW, Selsted ME, Severinov K, Shen B, Sivonen K, Smith L, Stein T, Süssmuth RD, Tagg JR, Tang GL, Truman AW, Vederas JC, Walsh CT, Walton JD, Wenzel SC, Willey JM, van der Donk WA. PMID: 23165928.
      View in: PubMed   Mentions: 377     Fields:    Translation:HumansCells
    17. Rhesus macaque theta defensins suppress inflammatory cytokines and enhance survival in mouse models of bacteremic sepsis. PLoS One. 2012; 7(12):e51337. Schaal JB, Tran D, Tran P, Ösapay G, Trinh K, Roberts KD, Brasky KM, Tongaonkar P, Ouellette AJ, Selsted ME. PMID: 23236475.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    18. Immunology. HD6 defensin nanonets. Science. 2012 Jul 27; 337(6093):420-1. Ouellette AJ, Selsted ME. PMID: 22837514.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    19. ?-Defensins: cyclic peptides with endless potential. J Biol Chem. 2012 Aug 03; 287(32):27014-9. Lehrer RI, Cole AM, Selsted ME. PMID: 22700960.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    20. High fidelity processing and activation of the human a-defensin HNP1 precursor by neutrophil elastase and proteinase 3. PLoS One. 2012; 7(3):e32469. Tongaonkar P, Golji AE, Tran P, Ouellette AJ, Selsted ME. PMID: 22448222.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    21. RTD-1mimic containing ?PNA scaffold exhibits broad-spectrum antibacterial activities. J Am Chem Soc. 2012 Mar 07; 134(9):4041-4. Rapireddy S, Nhon L, Meehan RE, Franks J, Stolz DB, Tran D, Selsted ME, Ly DH. PMID: 22332599.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    22. Alternative luminal activation mechanisms for paneth cell a-defensins. J Biol Chem. 2012 Mar 30; 287(14):11205-12. Mastroianni JR, Costales JK, Zaksheske J, Selsted ME, Salzman NH, Ouellette AJ. PMID: 22334698.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    23. Cycloquest: identification of cyclopeptides via database search of their mass spectra against genome databases. J Proteome Res. 2011 Oct 07; 10(10):4505-12. Mohimani H, Liu WT, Mylne JS, Poth AG, Colgrave ML, Tran D, Selsted ME, Dorrestein PC, Pevzner PA. PMID: 21851130.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    24. Criterion for amino acid composition of defensins and antimicrobial peptides based on geometry of membrane destabilization. J Am Chem Soc. 2011 May 04; 133(17):6720-7. Schmidt NW, Mishra A, Lai GH, Davis M, Sanders LK, Tran D, Garcia A, Tai KP, McCray PB, Ouellette AJ, Selsted ME, Wong GC. PMID: 21473577.
      View in: PubMed   Mentions: 61     Fields:    Translation:AnimalsCells
    25. Rhesus macaque ?-defensin isoforms: expression, antimicrobial activities, and demonstration of a prominent role in neutrophil granule microbicidal activities. J Leukoc Biol. 2011 Feb; 89(2):283-90. Tongaonkar P, Tran P, Roberts K, Schaal J, Osapay G, Tran D, Ouellette AJ, Selsted ME. PMID: 21084627.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    26. Cyclic and acyclic defensins inhibit human immunodeficiency virus type-1 replication by different mechanisms. PLoS One. 2010 Mar 17; 5(3):e9737. Seidel A, Ye Y, de Armas LR, Soto M, Yarosh W, Marcsisin RA, Tran D, Selsted ME, Camerini D. PMID: 20305815.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    27. Rhesus theta-defensin prevents death in a mouse model of severe acute respiratory syndrome coronavirus pulmonary disease. J Virol. 2009 Nov; 83(21):11385-90. Wohlford-Lenane CL, Meyerholz DK, Perlman S, Zhou H, Tran D, Selsted ME, McCray PB. PMID: 19710146.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    28. SDF2L1, a component of the endoplasmic reticulum chaperone complex, differentially interacts with {alpha}-, {beta}-, and {theta}-defensin propeptides. J Biol Chem. 2009 Feb 27; 284(9):5602-9. Tongaonkar P, Selsted ME. PMID: 19109254.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    29. The cell-penetrating peptide, Pep-1, has activity against intracellular chlamydial growth but not extracellular forms of Chlamydia trachomatis. J Antimicrob Chemother. 2009 Jan; 63(1):115-23. Park N, Yamanaka K, Tran D, Chandrangsu P, Akers JC, de Leon JC, Morrissette NS, Selsted ME, Tan M. PMID: 18957395.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    30. Synthesis, structure, and activities of an oral mucosal alpha-defensin from rhesus macaque. J Biol Chem. 2008 Dec 19; 283(51):35869-77. Vasudevan S, Yuan J, Osapay G, Tran P, Tai K, Liang W, Kumar V, Selsted ME, Cocco MJ. PMID: 18930922.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    31. Isolation, synthesis, and antimicrobial activities of naturally occurring theta-defensin isoforms from baboon leukocytes. Infect Immun. 2008 Dec; 76(12):5883-91. Garcia AE, Osapay G, Tran PA, Yuan J, Selsted ME. PMID: 18852242.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    32. Microbicidal properties and cytocidal selectivity of rhesus macaque theta defensins. Antimicrob Agents Chemother. 2008 Mar; 52(3):944-53. Tran D, Tran P, Roberts K, Osapay G, Schaal J, Ouellette A, Selsted ME. PMID: 18160518.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    33. A pocket guide to explorations of the defensin field. Curr Pharm Des. 2007; 13(30):3061-4. Selsted ME. PMID: 17979748.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    34. Bovine peptidoglycan recognition protein-S: antimicrobial activity, localization, secretion, and binding properties. J Immunol. 2006 Jan 15; 176(2):1154-62. Tydell CC, Yuan J, Tran P, Selsted ME. PMID: 16394004.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    35. Mammalian defensins in the antimicrobial immune response. Nat Immunol. 2005 Jun; 6(6):551-7. Selsted ME, Ouellette AJ. PMID: 15908936.
      View in: PubMed   Mentions: 319     Fields:    Translation:HumansAnimalsCells
    36. Theta-defensins: cyclic antimicrobial peptides produced by binary ligation of truncated alpha-defensins. Curr Protein Pept Sci. 2004 Oct; 5(5):365-71. Selsted ME. PMID: 15544531.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    37. Paneth cell alpha-defensins from rhesus macaque small intestine. Infect Immun. 2004 Mar; 72(3):1470-8. Tanabe H, Yuan J, Zaragoza MM, Dandekar S, Henschen-Edman A, Selsted ME, Ouellette AJ. PMID: 14977952.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    38. Structure-activity determinants in paneth cell alpha-defensins: loss-of-function in mouse cryptdin-4 by charge-reversal at arginine residue positions. J Biol Chem. 2004 Mar 19; 279(12):11976-83. Tanabe H, Qu X, Weeks CS, Cummings JE, Kolusheva S, Walsh KB, Jelinek R, Vanderlick TK, Selsted ME, Ouellette AJ. PMID: 14702345.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    39. In vitro activity of naturally occurring peptides (defensins) against Listeria monocytogenes. Cad Saude Publica. 1994 Dec; 10(4):440-5. Nascimento Mda G, Cullor JS, Selsted ME. PMID: 14676929.
      View in: PubMed   Mentions:    Fields:    
    40. Alpha-defensin expression during myelopoiesis: identification of cis and trans elements that regulate expression of NP-3 in rat promyelocytes. J Leukoc Biol. 2004 Feb; 75(2):332-41. Yamamoto CM, Banaiee N, Yount NY, Patel B, Selsted ME. PMID: 14634060.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    41. Quantitative interactions between cryptdin-4 amino terminal variants and membranes. Peptides. 2003 Nov; 24(11):1795-805. Satchell DP, Sheynis T, Kolusheva S, Cummings J, Vanderlick TK, Jelinek R, Selsted ME, Ouellette AJ. PMID: 15019212.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    42. alpha-Defensins can have anti-HIV activity but are not CD8 cell anti-HIV factors. AIDS. 2003 Sep 26; 17(14):F23-32. Mackewicz CE, Yuan J, Tran P, Diaz L, Mack E, Selsted ME, Levy JA. PMID: 14502030.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    43. Susceptibility of human and murine Chlamydia trachomatis serovars to granulocyte- and epithelium-derived antimicrobial peptides. J Pept Res. 2003 May; 61(5):237-42. Chong-Cerrillo C, Selsted ME, Peterson EM, de la Maza LM. PMID: 12662357.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    44. Antimicrobial properties of the Escherichia coli R1 plasmid host killing peptide. J Biotechnol. 2003 Jan 09; 100(1):1-12. Pecota DC, Osapay G, Selsted ME, Wood TK. PMID: 12413781.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    45. Antimicrobial peptides from human platelets. Infect Immun. 2002 Dec; 70(12):6524-33. Tang YQ, Yeaman MR, Selsted ME. PMID: 12438321.
      View in: PubMed   Mentions: 110     Fields:    Translation:HumansAnimalsCells
    46. Cryptdin 3 forms anion selective channels in cytoplasmic membranes of human embryonic kidney cells. Am J Physiol Gastrointest Liver Physiol. 2002 May; 282(5):G757-65. Yue G, Merlin D, Selsted ME, Lencer WI, Madara JL, Eaton DC. PMID: 11960772.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    47. Isolation, characterization, and antimicrobial properties of bovine oligosaccharide-binding protein. A microbicidal granule protein of eosinophils and neutrophils. J Biol Chem. 2002 May 31; 277(22):19658-64. Tydell CC, Yount N, Tran D, Yuan J, Selsted ME. PMID: 11880375.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    48. Homodimeric theta-defensins from rhesus macaque leukocytes: isolation, synthesis, antimicrobial activities, and bacterial binding properties of the cyclic peptides. J Biol Chem. 2002 Feb 01; 277(5):3079-84. Tran D, Tran PA, Tang YQ, Yuan J, Cole T, Selsted ME. PMID: 11675394.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    49. Cryptdin-3 induces novel apical conductance(s) in Cl- secretory, including cystic fibrosis, epithelia. Am J Physiol Cell Physiol. 2001 Feb; 280(2):C296-302. Merlin D, Yue G, Lencer WI, Selsted ME, Madara JL. PMID: 11208524.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    50. Human neutrophil-mediated nonoxidative antifungal activity against Cryptococcus neoformans. Infect Immun. 2000 Nov; 68(11):6257-64. Mambula SS, Simons ER, Hastey R, Selsted ME, Levitz SM. PMID: 11035733.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    51. Characterization of luminal paneth cell alpha-defensins in mouse small intestine. Attenuated antimicrobial activities of peptides with truncated amino termini. J Biol Chem. 2000 Oct 27; 275(43):33969-73. Ouellette AJ, Satchell DP, Hsieh MM, Hagen SJ, Selsted ME. PMID: 10942762.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    52. Identification of constituents of human neutrophil azurophil granules that mediate fungistasis against Histoplasma capsulatum. Infect Immun. 2000 Oct; 68(10):5668-72. Newman SL, Gootee L, Gabay JE, Selsted ME. PMID: 10992469.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    53. Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria. Nat Immunol. 2000 Aug; 1(2):113-8. Ayabe T, Satchell DP, Wilson CL, Parks WC, Selsted ME, Ouellette AJ. PMID: 11248802.
      View in: PubMed   Mentions: 268     Fields:    Translation:AnimalsCells
    54. Formation and characterization of a single Trp-Trp cross-link in indolicidin that confers protease stability without altering antimicrobial activity. J Biol Chem. 2000 Apr 21; 275(16):12017-22. Osapay K, Tran D, Ladokhin AS, White SH, Henschen AH, Selsted ME. PMID: 10766833.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    55. Peptide localization and gene structure of cryptdin 4, a differentially expressed mouse paneth cell alpha-defensin. Infect Immun. 1999 Dec; 67(12):6643-51. Ouellette AJ, Darmoul D, Tran D, Huttner KM, Yuan J, Selsted ME. PMID: 10569786.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    56. Isolation, characterization, cDNA cloning, and antimicrobial properties of two distinct subfamilies of alpha-defensins from rhesus macaque leukocytes. Infect Immun. 1999 Nov; 67(11):6139-44. Tang YQ, Yuan J, Miller CJ, Selsted ME. PMID: 10531277.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    57. A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated alpha-defensins. Science. 1999 Oct 15; 286(5439):498-502. Tang YQ, Yuan J, Osapay G, Osapay K, Tran D, Miller CJ, Ouellette AJ, Selsted ME. PMID: 10521339.
      View in: PubMed   Mentions: 166     Fields:    Translation:HumansAnimalsCells
    58. CD spectra of indolicidin antimicrobial peptides suggest turns, not polyproline helix. Biochemistry. 1999 Sep 21; 38(38):12313-9. Ladokhin AS, Selsted ME, White SH. PMID: 10493799.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    59. Cloning and expression of bovine neutrophil beta-defensins. Biosynthetic profile during neutrophilic maturation and localization of mature peptide to novel cytoplasmic dense granules. J Biol Chem. 1999 Sep 10; 274(37):26249-58. Yount NY, Yuan J, Tarver A, Castro T, Diamond G, Tran PA, Levy JN, McCullough C, Cullor JS, Bevins CL, Selsted ME. PMID: 10473579.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    60. Anti-HIV-1 activity of indolicidin, an antimicrobial peptide from neutrophils. J Leukoc Biol. 1998 Jan; 63(1):94-100. Robinson WE, McDougall B, Tran D, Selsted ME. PMID: 9469478.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    61. The t(8;21) fusion product, AML-1-ETO, associates with C/EBP-alpha, inhibits C/EBP-alpha-dependent transcription, and blocks granulocytic differentiation. Mol Cell Biol. 1998 Jan; 18(1):322-33. Westendorf JJ, Yamamoto CM, Lenny N, Downing JR, Selsted ME, Hiebert SW. PMID: 9418879.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansAnimalsCells
    62. Semidry electroblotting of peptides and proteins from acid-urea polyacrylamide gels. Anal Biochem. 1997 Nov 15; 253(2):225-30. Wang MS, Pang JS, Selsted ME. PMID: 9367507.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    63. Critical role of lipid composition in membrane permeabilization by rabbit neutrophil defensins. J Biol Chem. 1997 Sep 26; 272(39):24224-33. Hristova K, Selsted ME, White SH. PMID: 9305875.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    64. Induction of epithelial chloride secretion by channel-forming cryptdins 2 and 3. Proc Natl Acad Sci U S A. 1997 Aug 05; 94(16):8585-9. Lencer WI, Cheung G, Strohmeier GR, Currie MG, Ouellette AJ, Selsted ME, Madara JL. PMID: 9238020.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    65. Sizing membrane pores in lipid vesicles by leakage of co-encapsulated markers: pore formation by melittin. Biophys J. 1997 Apr; 72(4):1762-6. Ladokhin AS, Selsted ME, White SH. PMID: 9083680.
      View in: PubMed   Mentions: 54     Fields:    
    66. Purification and in vitro activities of rabbit platelet microbicidal proteins. Infect Immun. 1997 Mar; 65(3):1023-31. Yeaman MR, Tang YQ, Shen AJ, Bayer AS, Selsted ME. PMID: 9038312.
      View in: PubMed   Mentions: 56     Fields:    Translation:AnimalsCells
    67. Bilayer interactions of indolicidin, a small antimicrobial peptide rich in tryptophan, proline, and basic amino acids. Biophys J. 1997 Feb; 72(2 Pt 1):794-805. Ladokhin AS, Selsted ME, White SH. PMID: 9017204.
      View in: PubMed   Mentions: 41     Fields:    Translation:Animals
    68. HPLC methods for purification of antimicrobial peptides. Methods Mol Biol. 1997; 78:17-33. Selsted ME. PMID: 9276294.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    69. Cryptdin gene expression in developing mouse small intestine. Am J Physiol. 1997 Jan; 272(1 Pt 1):G197-206. Darmoul D, Brown D, Selsted ME, Ouellette AJ. PMID: 9038894.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    70. Interactions of monomeric rabbit neutrophil defensins with bilayers: comparison with dimeric human defensin HNP-2. Biochemistry. 1996 Sep 10; 35(36):11888-94. Hristova K, Selsted ME, White SH. PMID: 8794771.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    71. Paneth cell defensins: endogenous peptide components of intestinal host defense. FASEB J. 1996 Sep; 10(11):1280-9. Ouellette AJ, Selsted ME. PMID: 8836041.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimalsCells
    72. Purification, primary structures, and antibacterial activities of beta-defensins, a new family of antimicrobial peptides from bovine neutrophils. J Biol Chem. 1996 Jul 05; 271(27):16430. Selsted ME, Tang YQ, Morris WL, McGuire PA, Novotny MJ, Smith W, Henschen AH, Cullor JS. PMID: 8690735.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    73. Rat neutrophil defensins. Precursor structures and expression during neutrophilic myelopoiesis. J Immunol. 1995 Nov 01; 155(9):4476-84. Yount NY, Wang MS, Yuan J, Banaiee N, Ouellette AJ, Selsted ME. PMID: 7594610.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    74. Solution structure of bovine neutrophil beta-defensin-12: the peptide fold of the beta-defensins is identical to that of the classical defensins. Biochemistry. 1995 Oct 17; 34(41):13663-71. Zimmermann GR, Legault P, Selsted ME, Pardi A. PMID: 7577957.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    75. Structure, function, and membrane integration of defensins. Curr Opin Struct Biol. 1995 Aug; 5(4):521-7. White SH, Wimley WC, Selsted ME. PMID: 8528769.
      View in: PubMed   Mentions: 89     Fields:    Translation:HumansAnimalsCells
    76. Liposomal entrapment of the neutrophil-derived peptide indolicidin endows it with in vivo antifungal activity. Biochim Biophys Acta. 1995 Jul 26; 1237(2):109-14. Ahmad I, Perkins WR, Lupan DM, Selsted ME, Janoff AS. PMID: 7632702.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    77. Synthesis and characterization of indolicidin, a tryptophan-rich antimicrobial peptide from bovine neutrophils. Int J Pept Protein Res. 1995 May; 45(5):401-9. van Abel RJ, Tang YQ, Rao VS, Dobbs CH, Tran D, Barany G, Selsted ME. PMID: 7591479.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    78. Defensins in granules of phagocytic and non-phagocytic cells. Trends Cell Biol. 1995 Mar; 5(3):114-9. Selsted ME, Ouellette AJ. PMID: 14732166.
      View in: PubMed   Mentions: 22     Fields:    
    79. Killing of Giardia lamblia by cryptdins and cationic neutrophil peptides. Infect Immun. 1994 Dec; 62(12):5397-403. Aley SB, Zimmerman M, Hetsko M, Selsted ME, Gillin FD. PMID: 7960119.
      View in: PubMed   Mentions: 56     Fields:    Translation:AnimalsCells
    80. Mouse Paneth cell defensins: primary structures and antibacterial activities of numerous cryptdin isoforms. Infect Immun. 1994 Nov; 62(11):5040-7. Ouellette AJ, Hsieh MM, Nosek MT, Cano-Gauci DF, Huttner KM, Buick RN, Selsted ME. PMID: 7927786.
      View in: PubMed   Mentions: 61     Fields:    Translation:AnimalsCells
    81. Interactions between human defensins and lipid bilayers: evidence for formation of multimeric pores. Protein Sci. 1994 Sep; 3(9):1362-73. Wimley WC, Selsted ME, White SH. PMID: 7833799.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansCells
    82. Structure and dynamics of the neutrophil defensins NP-2, NP-5, and HNP-1: NMR studies of amide hydrogen exchange kinetics. Proteins. 1994 Sep; 20(1):52-67. Skalicky JJ, Selsted ME, Pardi A. PMID: 7824523.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    83. Myeloperoxidase (MPO) gene mutation in hereditary MPO deficiency. Blood. 1994 Apr 01; 83(7):1935-40. Kizaki M, Miller CW, Selsted ME, Koeffler HP. PMID: 8142659.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    84. Structure and diversity of the murine cryptdin gene family. Genomics. 1994 Feb; 19(3):448-53. Huttner KM, Selsted ME, Ouellette AJ. PMID: 8188287.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    85. Fungicidal properties of defensin NP-1 and activity against Cryptococcus neoformans in vitro. Antimicrob Agents Chemother. 1993 Dec; 37(12):2628-32. Alcouloumre MS, Ghannoum MA, Ibrahim AS, Selsted ME, Edwards JE. PMID: 8109927.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    86. Molecular analysis of myeloperoxidase deficiency shows heterogeneous patterns of the complete deficiency state manifested at the genomic, mRNA, and protein levels. Blood. 1993 Aug 15; 82(4):1317-22. Selsted ME, Miller CW, Novotny MJ, Morris WL, Koeffler HP. PMID: 8394754.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    87. Defensins promote fusion and lysis of negatively charged membranes. Protein Sci. 1993 Aug; 2(8):1301-12. Fujii G, Selsted ME, Eisenberg D. PMID: 8401215.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    88. Defensins are mitogenic for epithelial cells and fibroblasts. J Cell Physiol. 1993 May; 155(2):408-13. Murphy CJ, Foster BA, Mannis MJ, Selsted ME, Reid TW. PMID: 8482733.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    89. Purification, primary structures, and antibacterial activities of beta-defensins, a new family of antimicrobial peptides from bovine neutrophils. J Biol Chem. 1993 Mar 25; 268(9):6641-8. Selsted ME, Tang YQ, Morris WL, McGuire PA, Novotny MJ, Smith W, Henschen AH, Cullor JS. PMID: 8454635.
      View in: PubMed   Mentions: 85     Fields:    Translation:AnimalsCells
    90. Characterization of the disulfide motif in BNBD-12, an antimicrobial beta-defensin peptide from bovine neutrophils. J Biol Chem. 1993 Mar 25; 268(9):6649-53. Tang YQ, Selsted ME. PMID: 8454636.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    91. Investigational approaches for studying the structures and biological functions of myeloid antimicrobial peptides. Genet Eng (N Y). 1993; 15:131-47. Selsted ME. PMID: 7763838.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    92. NMR studies of defensin antimicrobial peptides. 2. Three-dimensional structures of rabbit NP-2 and human HNP-1. Biochemistry. 1992 Nov 24; 31(46):11357-64. Pardi A, Zhang XL, Selsted ME, Skalicky JJ, Yip PF. PMID: 1445873.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    93. NMR studies of defensin antimicrobial peptides. 1. Resonance assignment and secondary structure determination of rabbit NP-2 and human HNP-1. Biochemistry. 1992 Nov 24; 31(46):11348-56. Zhang XL, Selsted ME, Pardi A. PMID: 1445872.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    94. Enteric defensins: antibiotic peptide components of intestinal host defense. J Cell Biol. 1992 Aug; 118(4):929-36. Selsted ME, Miller SI, Henschen AH, Ouellette AJ. PMID: 1500431.
      View in: PubMed   Mentions: 82     Fields:    Translation:AnimalsCells
    95. Purification and primary structure of murine cryptdin-1, a Paneth cell defensin. FEBS Lett. 1992 Jun 15; 304(2-3):146-8. Ouellette AJ, Miller SI, Henschen AH, Selsted ME. PMID: 1618314.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    96. Indolicidin, a novel bactericidal tridecapeptide amide from neutrophils. J Biol Chem. 1992 Mar 05; 267(7):4292-5. Selsted ME, Novotny MJ, Morris WL, Tang YQ, Smith W, Cullor JS. PMID: 1537821.
      View in: PubMed   Mentions: 78     Fields:    Translation:AnimalsCells
    97. Bactericidal potency and mechanistic specificity of neutrophil defensins against bovine mastitis pathogens. Vet Microbiol. 1991 Sep; 29(1):49-58. Cullor JS, Wood S, Smith W, Panico L, Selsted ME. PMID: 1949554.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    98. Antimicrobial activity of rabbit leukocyte defensins against Treponema pallidum subsp. pallidum. Infect Immun. 1991 Apr; 59(4):1359-67. Borenstein LA, Selsted ME, Lehrer RI, Miller JN. PMID: 2004816.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    99. Crystal structure of defensin HNP-3, an amphiphilic dimer: mechanisms of membrane permeabilization. Science. 1991 Mar 22; 251(5000):1481-5. Hill CP, Yee J, Selsted ME, Eisenberg D. PMID: 2006422.
      View in: PubMed   Mentions: 97     Fields:    Translation:HumansAnimalsCells
    100. Defensins: endogenous antibiotic peptides of animal cells. Cell. 1991 Jan 25; 64(2):229-30. Lehrer RI, Ganz T, Selsted ME. PMID: 1988144.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsCells
    101. In vitro sensitivity of oral, gram-negative, facultative bacteria to the bactericidal activity of human neutrophil defensins. Infect Immun. 1990 Dec; 58(12):3934-40. Miyasaki KT, Bodeau AL, Ganz T, Selsted ME, Lehrer RI. PMID: 2254020.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    102. Killing of oral, gram-negative, facultative bacteria by the rabbit defensin, NP-1. Oral Microbiol Immunol. 1990 Dec; 5(6):315-9. Miyasaki KT, Bodeau AL, Selsted ME, Ganz T, Lehrer RI. PMID: 2098709.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    103. Characterization of defensin resistance phenotypes associated with mutations in the phoP virulence regulon of Salmonella typhimurium. Infect Immun. 1990 Nov; 58(11):3706-10. Miller SI, Pulkkinen WS, Selsted ME, Mekalanos JJ. PMID: 2172166.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimalsCells
    104. In vitro antimicrobial activity of defensins against ocular pathogens. Arch Ophthalmol. 1990 Jun; 108(6):861-4. Cullor JS, Mannis MJ, Murphy CJ, Smith WL, Selsted ME, Reid TW. PMID: 2112378.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    105. Defensins. Eur J Haematol. 1990 Jan; 44(1):1-8. Ganz T, Selsted ME, Lehrer RI. PMID: 2407547.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansAnimalsCells
    106. Antimicrobial defensin peptides form voltage-dependent ion-permeable channels in planar lipid bilayer membranes. Proc Natl Acad Sci U S A. 1990 Jan; 87(1):210-4. Kagan BL, Selsted ME, Ganz T, Lehrer RI. PMID: 1688654.
      View in: PubMed   Mentions: 138     Fields:    Translation:Cells
    107. Monocyte-chemotactic activity of defensins from human neutrophils. J Clin Invest. 1989 Dec; 84(6):2017-20. Territo MC, Ganz T, Selsted ME, Lehrer R. PMID: 2592571.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansCells
    108. Interaction of human defensins with Escherichia coli. Mechanism of bactericidal activity. J Clin Invest. 1989 Aug; 84(2):553-61. Lehrer RI, Barton A, Daher KA, Harwig SS, Ganz T, Selsted ME. PMID: 2668334.
      View in: PubMed   Mentions: 199     Fields:    Translation:HumansCells
    109. Purification and antimicrobial properties of three defensins from rat neutrophils. Infect Immun. 1989 Jul; 57(7):2021-7. Eisenhauer PB, Harwig SS, Szklarek D, Ganz T, Selsted ME, Lehrer RI. PMID: 2543629.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    110. Evidence for a pretranslational defect in hereditary and acquired myeloperoxidase deficiency. Blood. 1989 May 15; 73(7):1980-6. Tobler A, Selsted ME, Miller CW, Johnson KR, Novotny MJ, Rovera G, Koeffler HP. PMID: 2540860.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    111. Determination of the disulfide array in the human defensin HNP-2. A covalently cyclized peptide. J Biol Chem. 1989 Mar 05; 264(7):4003-7. Selsted ME, Harwig SS. PMID: 2917986.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    112. Regulation of gene expression of myeloperoxidase during myeloid differentiation. J Cell Physiol. 1988 Aug; 136(2):215-25. Tobler A, Miller CW, Johnson KR, Selsted ME, Rovera G, Koeffler HP. PMID: 2842344.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    113. Neutrophils and host defense. Ann Intern Med. 1988 Jul 15; 109(2):127-42. Lehrer RI, Ganz T, Selsted ME, Babior BM, Curnutte JT. PMID: 3289431.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansCells
    114. Solution structures of the rabbit neutrophil defensin NP-5. J Mol Biol. 1988 Jun 05; 201(3):625-36. Pardi A, Hare DR, Selsted ME, Morrison RD, Bassolino DA, Bach AC. PMID: 2843652.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    115. Synergistic cytolysis mediated by hydrogen peroxide combined with peptide defensins. Cell Immunol. 1988 Jun; 114(1):104-16. Lichtenstein AK, Ganz T, Selsted ME, Lehrer RI. PMID: 2836069.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    116. Modulation of the in vitro candidacidal activity of human neutrophil defensins by target cell metabolism and divalent cations. J Clin Invest. 1988 Jun; 81(6):1829-35. Lehrer RI, Ganz T, Szklarek D, Selsted ME. PMID: 3290255.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimalsCells
    117. Characterization of two crystal forms of human defensin neutrophil cationic peptide 1, a naturally occurring antimicrobial peptide of leukocytes. J Biol Chem. 1988 Apr 25; 263(12):5933-5. Stanfield RL, Westbrook EM, Selsted ME. PMID: 3356711.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    118. Mechanism of target cytolysis by peptide defensins. Target cell metabolic activities, possibly involving endocytosis, are crucial for expression of cytotoxicity. J Immunol. 1988 Apr 15; 140(8):2686-94. Lichtenstein AK, Ganz T, Nguyen TM, Selsted ME, Lehrer RI. PMID: 3162745.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    119. Inhibition of protein kinase C by defensins, antibiotic peptides from human neutrophils. Biochem Pharmacol. 1988 Mar 01; 37(5):951-6. Charp PA, Rice WG, Raynor RL, Reimund E, Kinkade JM, Ganz T, Selsted ME, Lehrer RI, Kuo JF. PMID: 3345204.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    120. Oxygen-independent bactericidal systems. Mechanisms and disorders. Hematol Oncol Clin North Am. 1988 Mar; 2(1):159-69. Lehrer RI, Ganz T, Selsted ME. PMID: 3279018.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    121. Purification, primary structure, and antimicrobial activities of a guinea pig neutrophil defensin. Infect Immun. 1987 Sep; 55(9):2281-6. Selsted ME, Harwig SS. PMID: 3623703.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    122. Defensin-rich dense granules of human neutrophils. Blood. 1987 Sep; 70(3):757-65. Rice WG, Ganz T, Kinkade JM, Selsted ME, Lehrer RI, Parmley RT. PMID: 3040155.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    123. Two-dimensional NMR studies of the antimicrobial peptide NP-5. Biochemistry. 1987 Jul 14; 26(14):4389-97. Bach AC, Selsted ME, Pardi A. PMID: 3663594.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    124. Characterization of cDNA clones for human myeloperoxidase: predicted amino acid sequence and evidence for multiple mRNA species. Nucleic Acids Res. 1987 Mar 11; 15(5):2013-28. Johnson KR, Nauseef WM, Care A, Wheelock MJ, Shane S, Hudson S, Koeffler HP, Selsted M, Miller C, Rovera G. PMID: 3031585.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    125. Direct inactivation of viruses by human granulocyte defensins. J Virol. 1986 Dec; 60(3):1068-74. Daher KA, Selsted ME, Lehrer RI. PMID: 3023659.
      View in: PubMed   Mentions: 114     Fields:    Translation:HumansCells
    126. In vitro tumor cell cytolysis mediated by peptide defensins of human and rabbit granulocytes. Blood. 1986 Dec; 68(6):1407-10. Lichtenstein A, Ganz T, Selsted ME, Lehrer RI. PMID: 3779104.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimalsCells
    127. In vitro killing of spores and hyphae of Aspergillus fumigatus and Rhizopus oryzae by rabbit neutrophil cationic peptides and bronchoalveolar macrophages. J Infect Dis. 1986 Sep; 154(3):483-9. Levitz SM, Selsted ME, Ganz T, Lehrer RI, Diamond RD. PMID: 3525696.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    128. Eosin Y: a reversible stain for detecting electrophoretically resolved protein. Anal Biochem. 1986 Jun; 155(2):270-4. Selsted ME, Becker HW. PMID: 2425660.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    129. Synergistic activity of rabbit granulocyte peptides against Candida albicans. Infect Immun. 1986 Jun; 52(3):902-4. Lehrer RI, Szklarek D, Ganz T, Selsted ME. PMID: 3519465.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    130. Antimicrobial activity of phagocyte granule proteins. Semin Respir Infect. 1986 Jun; 1(2):107-17. Ganz T, Selsted ME, Lehrer RI. PMID: 3317602.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    131. Defensins. Natural peptide antibiotics of human neutrophils. J Clin Invest. 1985 Oct; 76(4):1427-35. Ganz T, Selsted ME, Szklarek D, Harwig SS, Daher K, Bainton DF, Lehrer RI. PMID: 2997278.
      View in: PubMed   Mentions: 336     Fields:    Translation:HumansAnimalsCells
    132. Newborn rabbit alveolar macrophages are deficient in two microbicidal cationic peptides, MCP-1 and MCP-2. Am Rev Respir Dis. 1985 Oct; 132(4):901-4. Ganz T, Sherman MP, Selsted ME, Lehrer RI. PMID: 4051325.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    133. Primary structures of three human neutrophil defensins. J Clin Invest. 1985 Oct; 76(4):1436-9. Selsted ME, Harwig SS, Ganz T, Schilling JW, Lehrer RI. PMID: 4056036.
      View in: PubMed   Mentions: 125     Fields:    Translation:HumansAnimalsCells
    134. Activity of rabbit leukocyte peptides against Candida albicans. Infect Immun. 1985 Jul; 49(1):202-6. Selsted ME, Szklarek D, Ganz T, Lehrer RI. PMID: 3891624.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    135. Correlation of binding of rabbit granulocyte peptides to Candida albicans with candidacidal activity. Infect Immun. 1985 Jul; 49(1):207-11. Lehrer RI, Szklarek D, Ganz T, Selsted ME. PMID: 3891625.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    136. Direct inactivation of viruses by MCP-1 and MCP-2, natural peptide antibiotics from rabbit leukocytes. J Virol. 1985 May; 54(2):467-72. Lehrer RI, Daher K, Ganz T, Selsted ME. PMID: 2985808.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    137. Opsonic activity of MCP-1 and MCP-2, cationic peptides from rabbit alveolar macrophages. Diagn Microbiol Infect Dis. 1985 May; 3(3):233-42. Fleischmann J, Selsted ME, Lehrer RI. PMID: 3888509.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    138. In vitro effect of phagocyte cationic peptides on Coccidioides immitis. J Infect Dis. 1985 May; 151(5):890-4. Segal GP, Lehrer RI, Selsted ME. PMID: 3989323.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    139. Primary structures of six antimicrobial peptides of rabbit peritoneal neutrophils. J Biol Chem. 1985 Apr 25; 260(8):4579-84. Selsted ME, Brown DM, DeLange RJ, Harwig SS, Lehrer RI. PMID: 3988726.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    140. Divergent expression of cytotoxic and microbicidal functions of rabbit alveolar and peritoneal macrophages: effects of non-specific activation and a natural microbicidal peptide, MCP-1. Aust J Exp Biol Med Sci. 1985 Feb; 63 ( Pt 1):53-63. Sorrell TC, Lehrer RI, Ferrari LG, Müller M, Selsted ME. PMID: 3893405.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    141. Characterization of two crystal forms of neutrophil cationic protein NP2, a naturally occurring broad-spectrum antimicrobial agent from leukocytes. J Mol Biol. 1984 Sep 25; 178(3):783-5. Westbrook EM, Lehrer RI, Selsted ME. PMID: 6492164.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    142. Purification and characterization of human T-lymphocyte-derived erythroid-potentiating activity. J Biol Chem. 1984 Aug 25; 259(16):9992-6. Westbrook CA, Gasson JC, Gerber SE, Selsted ME, Golde DW. PMID: 6332112.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    143. Purification and antibacterial activity of antimicrobial peptides of rabbit granulocytes. Infect Immun. 1984 Jul; 45(1):150-4. Selsted ME, Szklarek D, Lehrer RI. PMID: 6735465.
      View in: PubMed   Mentions: 98     Fields:    Translation:AnimalsCells
    144. Primary structures of MCP-1 and MCP-2, natural peptide antibiotics of rabbit lung macrophages. J Biol Chem. 1983 Dec 10; 258(23):14485-9. Selsted ME, Brown DM, DeLange RJ, Lehrer RI. PMID: 6643497.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    145. Antibacterial activity of microbicidal cationic proteins 1 and 2, natural peptide antibiotics of rabbit lung macrophages. Infect Immun. 1983 Oct; 42(1):10-4. Lehrer RI, Selsted ME, Szklarek D, Fleischmann J. PMID: 6413408.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    146. Isolation and purification of bactericides from human tears. Exp Eye Res. 1982 Mar; 34(3):305-18. Selsted ME, Martinez RJ. PMID: 7067743.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    147. Increased content of microbicidal cationic peptides in rabbit alveolar macrophages elicited by complete Freund adjuvant. Infect Immun. 1981 Sep; 33(3):775-8. Lehrer RI, Szklarek D, Selsted ME, Fleischmann J. PMID: 7287180.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    148. Microbicidal and cytotoxic properties of soluble components from quaternary aminoethyl-sephadex. Infect Immun. 1980 Dec; 30(3):887-9. Selsted ME, Martinez RJ. PMID: 7228393.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    149. A simple and ultrasensitive enzymatic assay for the quantitative determination of lysozyme in the picogram range. Anal Biochem. 1980 Nov 15; 109(1):67-70. Selsted ME, Martinez RJ. PMID: 7469020.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    150. Lysozyme: primary bactericidin in human plasma serum active against Bacillus subtilis. Infect Immun. 1978 Jun; 20(3):782-91. Selsted ME, Martinez RJ. PMID: 97236.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
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