Justin Schaal, PhD

Title(s)Assistant Professor of Research Pathology
SchoolKeck School of Medicine of Usc
Phone+1 323 442 7814
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Preclinical Pharmacokinetics and Safety of Intravenous RTD-1. Antimicrob Agents Chemother. 2022 03 15; 66(3):e0212521. Park AYJ, Tran DQ, Schaal JB, Wang M, Selsted ME, Beringer PM. PMID: 35041507; PMCID: PMC8923172.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    2. A host-directed macrocyclic peptide therapeutic for MDR gram negative bacterial infections. Sci Rep. 2021 12 06; 11(1):23447. Schaal JB, Eriguchi Y, Tran DQ, Tran PA, Hawes C, Cabebe AE, Pike K, Trinh K, Ouellette AJ, Selsted ME. PMID: 34873199; PMCID: PMC8648872.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    3. RTD-1 therapeutically normalizes synovial gene signatures in rat autoimmune arthritis and suppresses proinflammatory mediators in RA synovial fibroblasts. Physiol Genomics. 2019 12 01; 51(12):657-667. Tongaonkar P, Punj V, Subramanian A, Tran DQ, Trinh KK, Schaal JB, Laragione T, Ouellette AJ, Gulko PS, Selsted ME. PMID: 31762409; PMCID: PMC6962595.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    4. Rhesus Theta Defensin 1 Promotes Long Term Survival in Systemic Candidiasis by Host Directed Mechanisms. Sci Rep. 2019 11 15; 9(1):16905. Basso V, Tran DQ, Schaal JB, Tran P, Eriguchi Y, Ngole D, Cabebe AE, Park AY, Beringer PM, Ouellette AJ, Selsted ME. PMID: 31729441; PMCID: PMC6858451.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    5. Fungicidal Potency and Mechanisms of θ-Defensins against Multidrug-Resistant Candida Species. Antimicrob Agents Chemother. 2018 06; 62(6). Basso V, Garcia A, Tran DQ, Schaal JB, Tran P, Ngole D, Aqeel Y, Tongaonkar P, Ouellette AJ, Selsted ME. PMID: 29610196; PMCID: PMC5971616.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    6. Rhesus θ-Defensin-1 Attenuates Endotoxin-induced Acute Lung Injury by Inhibiting Proinflammatory Cytokines and Neutrophil Recruitment. Am J Respir Cell Mol Biol. 2018 03; 58(3):310-319. Jayne JG, Bensman TJ, Schaal JB, Park AYJ, Kimura E, Tran D, Selsted ME, Beringer PM. PMID: 28954201; PMCID: PMC5854954.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    7. Macrocyclic θ-defensins suppress tumor necrosis factor-α (TNF-α) shedding by inhibition of TNF-α-converting enzyme. J Biol Chem. 2018 02 23; 293(8):2725-2734. Schaal JB, Maretzky T, Tran DQ, Tran PA, Tongaonkar P, Blobel CP, Ouellette AJ, Selsted ME. PMID: 29317500; PMCID: PMC5827436.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    8. Suppression and resolution of autoimmune arthritis by rhesus θ-defensin-1, an immunomodulatory macrocyclic peptide. PLoS One. 2017; 12(11):e0187868. Schaal JB, Tran DQ, Subramanian A, Patel R, Laragione T, Roberts KD, Trinh K, Tongaonkar P, Tran PA, Minond D, Fields GB, Beringer P, Ouellette AJ, Gulko PS, Selsted ME. PMID: 29145473; PMCID: PMC5690597.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    9. Efficacy of Rhesus Theta-Defensin-1 in Experimental Models of Pseudomonas aeruginosa Lung Infection and Inflammation. Antimicrob Agents Chemother. 2017 08; 61(8). Bensman TJ, Jayne JG, Sun M, Kimura E, Meinert J, Wang JC, Schaal JB, Tran D, Rao AP, Akbari O, Selsted ME, Beringer PM. PMID: 28559270; PMCID: PMC5527632.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    10. Rhesus macaque θ-defensin RTD-1 inhibits proinflammatory cytokine secretion and gene expression by inhibiting the activation of NF-κB and MAPK pathways. J Leukoc Biol. 2015 Dec; 98(6):1061-70. Tongaonkar P, Trinh KK, Schaal JB, Tran D, Gulko PS, Ouellette AJ, Selsted ME. PMID: 26269197; PMCID: PMC4661038.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    11. Killing of staphylococci by θ-defensins involves membrane impairment and activation of autolytic enzymes. Antibiotics (Basel). 2014; 3(4):617-31. Wilmes M, Stockem M, Bierbaum G, Schlag M, Götz F, Tran DQ, Schaal JB, Ouellette AJ, Selsted ME, Sahl HG. PMID: 25632351; PMCID: PMC4306331.
      View in: PubMed   Mentions: 13  
    12. Rhesus macaque theta defensins suppress inflammatory cytokines and enhance survival in mouse models of bacteremic sepsis. PLoS One. 2012; 7(12):e51337. Schaal JB, Tran D, Tran P, Ösapay G, Trinh K, Roberts KD, Brasky KM, Tongaonkar P, Ouellette AJ, Selsted ME. PMID: 23236475; PMCID: PMC3516535.
      View in: PubMed   Mentions: 37     Fields:    Translation:Animals
    13. Rhesus macaque θ-defensin isoforms: expression, antimicrobial activities, and demonstration of a prominent role in neutrophil granule microbicidal activities. J Leukoc Biol. 2011 Feb; 89(2):283-90. Tongaonkar P, Tran P, Roberts K, Schaal J, Osapay G, Tran D, Ouellette AJ, Selsted ME. PMID: 21084627; PMCID: PMC3024902.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    14. Microbicidal properties and cytocidal selectivity of rhesus macaque theta defensins. Antimicrob Agents Chemother. 2008 Mar; 52(3):944-53. Tran D, Tran P, Roberts K, Osapay G, Schaal J, Ouellette A, Selsted ME. PMID: 18160518; PMCID: PMC2258523.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
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    NIH Funding Acknowledgment: Important - All publications resulting from the utilization of SC CTSI resources are required to credit the SC CTSI grant by including the NIH funding acknowledgment and must comply with the NIH Public Access Policy.

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