Joni Kristin Doherty, MD, PhD

Title(s)Associate Professor of Clinical Otolaryngology-Head and Neck Surgery
SchoolKeck School of Medicine of Usc
Address1537 Norfolk Street Street
Health Sciences Campus
Los Angeles CA 90033
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    Other Positions
    Title(s)Division Chief of Otology, Neurotology, and Skull Base Surgery


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    Dr. Joni Kristin Doherty’s clinic interests include chronic ear disease, otosclerosis, cochlear implantation, vestibular disorders, and skull base tumors including acoustic neuromas and meningiomas.

    Dr. Doherty has conducted cutting-edge research on the genetics and biology of inner ear disorders at the House Ear Institute, the University of California, San Diego, and the University of California, Los Angeles funded by the National Institutes of Health (NIH).

    Dr. Doherty has authored numerous research publications and textbook chapters in her field. She is a member of the American Academy of Otolaryngology – Head and Neck Surgery. Dr. Doherty is committed to offering high quality, compassionate care to patients in her clinic, while pursuing clinical advancements in the field of Otology & Neurotology.

    Dr. Doherty graduated with Honors from UCLA, and earned her medical degree and doctorate degree (PhD) in Cell Biology from The Oregon Health & Sciences University. She completed her residency in Otolaryngology –Head and Neck Surgery here at our very own University of Southern California and her fellowship at the world renowned House Clinic in Los Angeles.

    After fellowship, she joined the faculty at UCSD and was awarded an NIH training grant for her research on vestibular schwannoma (a.k.a., acoustic neuroma) biology. She later joined the House Research Institute as a senior scientist while working half-time in Neurotology practice in Orange County before joining USC.


    https://keck.usc.edu/otolaryngology/
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    ErbB receptor regulation of Vestibular Schwannomas
    NIH K08DC008523Jul 6, 2007 - Jun 30, 2012
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. External Auditory Canal Exostosis and the California Surfer Population: A Cross-Sectional Study. Laryngoscope. 2025 Jan; 135(1):286-292. Davis RJ, Ayo-Ajibola O, Lin ME, Doherty JK. PMID: 39109803; PMCID: PMC11635140.
      View in: PubMed   Mentions:    Fields:    
    2. Music to Define a Generation: Factors Associated With Hearing Protection Use at Music Venues. Otol Neurotol. 2024 Aug 01; 45(7):745-753. Lin ME, Long R, Iyer A, Ayo-Ajibola O, Choi JS, Doherty JK. PMID: 38896784.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Utilization of Face-to-Face Vestibular Support Groups: A Comparison to Online Group Participation. Ann Otol Rhinol Laryngol. 2024 Aug; 133(8):713-719. Vanstrum EB, Jung Kim M, Ziltzer RS, Doherty JK, Bassett AM. PMID: 38738670; PMCID: PMC11290019.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Disparities in Sporadic Vestibular Schwannoma Initial Presentation Between a Public Safety Net Hospital and Tertiary Academic Medical Center at the Same Zip Code 2010 to 2020. Ann Otol Rhinol Laryngol. 2024 Jun; 133(6):605-612. Cutri RM, Lin J, Wilson ML, Doherty JK, Pan DW. PMID: 38517145.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Imaging as an early biomarker to predict sensitivity to everolimus for progressive NF2-related vestibular schwannoma. J Neurooncol. 2024 Apr; 167(2):339-348. Nghiemphu PL, Vitte J, Dombi E, Nguyen T, Wagle N, Ishiyama A, Sepahdari AR, Cachia D, Widemann BC, Brackmann DE, Doherty JK, Kalamarides M, Giovannini M. PMID: 38372904; PMCID: PMC11023969.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    6. New Paradigm of Music Listening: Hearing Protection Perceptions and Treatment Decision-Making Among Music Venue Attendees. Otolaryngol Head Neck Surg. 2024 Mar; 170(3):776-787. Long R, Lin ME, Iyer A, Ayo-Ajibola O, Choi JS, Doherty J. PMID: 37811692.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Association between Cannabis Use and Tinnitus in US Adults. Otol Neurotol. 2023 07 01; 44(6):611-618. Reyes Orozco F, Lin M, Clark B, Doherty JK, Oghalai JS, Voelker CCJ, Choi JS. PMID: 37254263.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    8. Comprehensive Management of Headache for the Otolaryngologist: A Summary. Otolaryngol Clin North Am. 2022 Jun; 55(3S):e1-e8. Kulich M, Setzen M, Doherty J. PMID: 35987560.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Nummular and Side-locked Headaches for the Otolaryngologist. Otolaryngol Clin North Am. 2022 Jun; 55(3):697-706. Zhou S, Badash I, Doherty JK. PMID: 35490038.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Idiopathic Intracranial Hypertension: Implications for the Otolaryngologist. Otolaryngol Clin North Am. 2022 Jun; 55(3):579-594. Pan DW, Vanstrum E, Doherty JK. PMID: 35490040.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    11. Comprehensive Headache Evaluation and Management for the Otolaryngologist. Otolaryngol Clin North Am. 2022 06; 55(3):xvii-xviii. Doherty JK, Setzen M. PMID: 35490041.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Headache in Pregnancy. Otolaryngol Clin North Am. 2022 Jun; 55(3):681-696. Magro I, Nurimba M, Doherty JK. PMID: 35490045.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Temporomandibular Joint Syndrome from an Ear Versus Dental-Related Standpoint. Otolaryngol Clin North Am. 2022 Jun; 55(3):649-658. Garcia E, Flores RE, Doherty JK. PMID: 35490046.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    14. Trends in Hearing Protection Use With Occupational Noise Exposure in the United States 1999 to 2016. Otol Neurotol. 2022 01 01; 43(1):e14-e22. Pan DW, Choi JS, Hokan A, Doherty JK. PMID: 34510117.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    15. An Exploration of Online Support Community Participation Among Patients With Vestibular Disorders. Laryngoscope. 2022 09; 132(9):1835-1842. Vanstrum EB, Doherty JK, Sinha UK, Voelker CCJ, Bassett AM. PMID: 34889460.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    16. Comparing Light-Driven Contact Hearing Aids with Acoustic Hearing Aids: Data and Clinical Tips. Audiol Neurootol. 2020; 25(5):283-290. Shohet J, Bibee J, Doherty J, Tanita C, Patzkowski G, Gende D. PMID: 32403110.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. Prevalence of Tinnitus and Associated Factors Among Asian Americans: Results From a National Sample. Laryngoscope. 2020 12; 130(12):E933-E940. Choi JS, Yu AJ, Voelker CCJ, Doherty JK, Oghalai JS, Fisher LM. PMID: 31977073.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    18. Contributions of Contemporary Human Temporal Bone Histopathology to Clinical Otology. Otolaryngol Head Neck Surg. 2019 11; 161(5):725-733. Tucci DL, Doherty JK. PMID: 31359831.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    19. Quality improvement in neurology: Neuro-otology quality measurement set. Neurology. 2018 10 09; 91(15):697-701. Rizk H, Agrawal Y, Barthel S, Bennett ML, Doherty JK, Gerend P, Gold DR, Morrill D, Oas JG, Roberts JK, Woodson E, Zapala DA, Bennett A, Shenoy AM. PMID: 30171079.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    20. Quality Improvement in Neurology: Neurotology Quality Measurement Set. Otolaryngol Head Neck Surg. 2018 10; 159(4):603-607. Rizk H, Agrawal Y, Barthel S, Bennett ML, Doherty JK, Gerend P, Gold DR, Morrill D, Oas JG, Roberts JK, Woodson E, Zapala DA, Bennett A, Shenoy AM. PMID: 30168353.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    21. Cochlear implant histopathology. World J Otorhinolaryngol Head Neck Surg. 2017 Dec; 3(4):211-213. Linthicum FH, Doherty JK, Lopez IA, Ishiyama A. PMID: 29780964; PMCID: PMC5956136.
      View in: PubMed   Mentions: 10  
    22. Post Hybrid Cochlear Implant Hearing Loss and Endolymphatic Hydrops. Otol Neurotol. 2016 12; 37(10):1516-1521. Ishiyama A, Doherty J, Ishiyama G, Quesnel AM, Lopez I, Linthicum FH. PMID: 27608418; PMCID: PMC5102757.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    23. Identification of target proteins involved in cochlear otosclerosis. Otol Neurotol. 2015 Jun; 36(5):923-31. Richard C, Doherty JK, Fayad JN, Cordero A, Linthicum FH. PMID: 25569361; PMCID: PMC4431897.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    24. Schwannomas exhibit distinct size-dependent gene-expression patterns. Future Oncol. 2015; 11(12):1751-8. Mehrian-Shai R, Freedman S, Shams S, Doherty J, Slattery W, Hsu NY, Reichardt JK, Andalibi A, Toren A. PMID: 26075443.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    25. Neurofibromatosis 2 invasion of the internal auditory canal wall: clinical significance. Otol Neurotol. 2014 Oct; 35(9):1662-8. Doherty J, Go JL, Linthicum FH. PMID: 25118583; PMCID: PMC4165688.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    26. Novel age-dependent targets in vestibular schwannomas. Hum Genomics. 2014 Jun 30; 8:10. Toren A, Reichardt JK, Andalibi A, Hsu NY, Doherty J, Slattery W, Mehrian-Shai R. PMID: 24980480; PMCID: PMC4097955.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    27. The periductal channels of the endolymphatic duct, hydrodynamic implications. Otolaryngol Head Neck Surg. 2014 Mar; 150(3):441-7. Linthicum FH, Doherty J, Webster P, Makarem A. PMID: 24376120; PMCID: PMC4034528.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    28. Idiopathic sudden sensorineural hearing loss: vascular or viral? Otolaryngol Head Neck Surg. 2013 Dec; 149(6):914-7. Linthicum FH, Doherty J, Berliner KI. PMID: 24067949; PMCID: PMC4068115.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    29. Temporal bone histopathology case of the month: Incidental discovery of a temporal bone chondroblastoma on an archived histopathologic section. Otol Neurotol. 2013 Jul; 34(5):e38-9. Richard C, Linthicum FH, Doherty JK. PMID: 23187929; PMCID: PMC3594476.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    30. Short-term histopathology effects of gamma knife radiosurgery on a vestibular schwannoma. Otolaryngol Head Neck Surg. 2013 Jun; 148(6):1056-8. Cassis A, Doherty JK, Daspit CP, Linthicum FH. PMID: 23426712; PMCID: PMC3862072.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    31. Recurrent schwannoma postirradiation: histological review reveals mixed schwannoma and meningioma. Otolaryngol Head Neck Surg. 2013 May; 148(5):886-8. Kimmel RA, Doherty J, Slattery WH, Linthicum FH. PMID: 23380761; PMCID: PMC3757934.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    32. Adipose replacing intracochlear architecture after meningioma removal. Otol Neurotol. 2013 Feb; 34(2):e8-9. Doherty JK, Linthicum FH. PMID: 22972425; PMCID: PMC3995125.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    33. Temporal bone histopathology case of the month: Modiolar dehiscence associated with sensorineural hearing loss. Otol Neurotol. 2013 Jan; 34(1):e4-5. Treadway JP, Doherty JK, Linthicum FH. PMID: 23235552; PMCID: PMC3995123.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    34. Activation of PDGFR and EGFR promotes the acquisition of a stem cell-like phenotype in schwannomas. Otol Neurotol. 2012 Dec; 33(9):1640-7. Yi D, Kuo SZ, Zheng H, Abhold EL, Brown CM, Doherty JK, Wang-Rodriguez J, Harris JP, Ongkeko WM. PMID: 22935817.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    35. Round window versus cochleostomy technique in cochlear implantation: histologic findings. Otol Neurotol. 2012 Sep; 33(7):1181-7. Richard C, Fayad JN, Doherty J, Linthicum FH. PMID: 22892806; PMCID: PMC3425957.
      View in: PubMed   Mentions: 51     Fields:    Translation:Humans
    36. ErbB expression, activation, and inhibition with lapatinib and tyrphostin (AG825) in human vestibular schwannomas. Otol Neurotol. 2011 Jul; 32(5):841-7. Ahmad ZK, Brown CM, Cueva RA, Ryan AF, Doherty JK. PMID: 21659924; PMCID: PMC3584631.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    37. Comparative case series of exostoses and osteomas of the internal auditory canal. Ann Otol Rhinol Laryngol. 2011 Apr; 120(4):255-60. Baik FM, Nguyen L, Doherty JK, Harris JP, Mafee MF, Nguyen QT. PMID: 21585156.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    38. EGF and bFGF promote invasion that is modulated by PI3/Akt kinase and Erk in vestibular schwannoma. Otol Neurotol. 2011 Feb; 32(2):308-14. Blair KJ, Kiang A, Wang-Rodriguez J, Yu MA, Doherty JK, Ongkeko WM. PMID: 21178801.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    39. Estrogen receptor expression in sporadic vestibular schwannomas. Otol Neurotol. 2011 Jan; 32(1):158-62. Brown CM, Ahmad ZK, Ryan AF, Doherty JK. PMID: 21099731; PMCID: PMC3073320.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    40. Potential role of imatinib mesylate (Gleevec, STI-571) in the treatment of vestibular schwannoma. Otol Neurotol. 2011 Jan; 32(1):163-70. Altuna X, Lopez JP, Yu MA, Arandazi MJ, Harris JP, Wang-Rodriguez J, An Y, Dobrow R, Doherty JK, Ongkeko WM. PMID: 21157293.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    41. Endolymphatic sac shunt, labyrinthectomy, and vestibular nerve section in Meniere's disease. Otolaryngol Clin North Am. 2010 Oct; 43(5):1091-111. Teufert KB, Doherty J. PMID: 20713247.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    42. Merlin knockdown in human Schwann cells: clues to vestibular schwannoma tumorigenesis. Otol Neurotol. 2010 Apr; 31(3):460-6. Ahmad Z, Brown CM, Patel AK, Ryan AF, Ongkeko R, Doherty JK. PMID: 20195187; PMCID: PMC2873969.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    43. Laterality of exostosis in surfers due to evaporative cooling effect. Otol Neurotol. 2010 Feb; 31(2):345-51. King JF, Kinney AC, Iacobellis SF, Alexander TH, Harris JP, Torre P, Doherty JK, Nguyen QT. PMID: 19806064.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    44. Exostoses and osteomas of the internal auditory canal. Laryngoscope. 2010; 120 Suppl 4:S215. Nguyen LT, Baik FM, Doherty JK, Harris JP, Nguyen QT. PMID: 21225813.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    45. Concordance of bilateral vestibular schwannoma growth and hearing changes in neurofibromatosis 2: neurofibromatosis 2 natural history consortium. Otol Neurotol. 2009 Sep; 30(6):835-41. Fisher LM, Doherty JK, Lev MH, Slattery WH. PMID: 19704365.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    46. Cellular targeting for cochlear gene therapy. Adv Otorhinolaryngol. 2009; 66:99-115. Ryan AF, Mullen LM, Doherty JK. PMID: 19494575; PMCID: PMC4379510.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    47. Vestibular schwannoma quantitative polymerase chain reaction expression of estrogen and progesterone receptors. Laryngoscope. 2008 Aug; 118(8):1458-63. Patel AK, Alexander TH, Andalibi A, Ryan AF, Doherty JK. PMID: 18670322; PMCID: PMC3570025.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    48. ErbB and Nrg: potential molecular targets for vestibular schwannoma pharmacotherapy. Otol Neurotol. 2008 Jan; 29(1):50-7. Doherty JK, Ongkeko W, Crawley B, Andalibi A, Ryan AF. PMID: 18199957.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    49. Distribution of nonvestibular cranial nerve schwannomas in neurofibromatosis 2. Otol Neurotol. 2007 Dec; 28(8):1083-90. Fisher LM, Doherty JK, Lev MH, Slattery WH. PMID: 18043434.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    50. Facial palsy and fallopian canal expansion associated with idiopathic intracranial hypertension. Otol Neurotol. 2007 Aug; 28(5):715-8. Brackmann DE, Doherty JK. PMID: 17667777.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    51. CPA melanoma: diagnosis and management. Otol Neurotol. 2007 Jun; 28(4):529-37. Brackmann DE, Doherty JK. PMID: 17414177.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    52. Endolymphatic sac tumor: a report of 3 cases and discussion of management. Ear Nose Throat J. 2007 Jan; 86(1):30-5. Doherty JK, Yong M, Maceri D. PMID: 17315832.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    53. Controversies in building a management algorithm for vestibular schwannomas. Curr Opin Otolaryngol Head Neck Surg. 2006 Oct; 14(5):305-13. Doherty JK, Friedman RA. PMID: 16974142.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    54. Meniere's disease: prevalence of contralateral ear involvement. Otol Neurotol. 2006 Apr; 27(3):355-61. House JW, Doherty JK, Fisher LM, Derebery MJ, Berliner KI. PMID: 16639274.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    55. Ossicular discontinuity and exostoses in Proteus syndrome: a case report. Ann Otol Rhinol Laryngol. 2005 Mar; 114(3):242-6. Doherty JK, Maceri DR. PMID: 15825577.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    56. Cochlear endosteal erosion with focal osteomyelitis induced by cochlear implantation. Otol Neurotol. 2004 Nov; 25(6):1029-30. Doherty JK, Linthicum FH. PMID: 15547439.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    57. Spiral ligament and stria vascularis changes in cochlear otosclerosis: effect on hearing level. Otol Neurotol. 2004 Jul; 25(4):457-64. Doherty JK, Linthicum FH. PMID: 15241221.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    58. Pathology quiz case 2. Pemphigus vulgaris (PV). Arch Otolaryngol Head Neck Surg. 2003 Feb; 129(2):254, 256-7. Doherty JK, Lum C, Doherty C. PMID: 12578463.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    59. Autologous fat grafting for the refractory patulous eustachian tube. Otolaryngol Head Neck Surg. 2003 Jan; 128(1):88-91. Doherty JK, Slattery WH. PMID: 12574764.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    60. Expression of herstatin, an autoinhibitor of HER-2/neu, inhibits transactivation of HER-3 by HER-2 and blocks EGF activation of the EGF receptor. Oncogene. 2001 Aug 23; 20(37):5199-209. Azios NG, Romero FJ, Denton MC, Doherty JK, Clinton GM. PMID: 11526509.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
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