Loading...

Janet Laurie Sobell, PhD

Title(s)Associate Professor of Research Psychiatry and the Behavioral Sciences
AddressZNI 401 1501 San Pablo Street
Health Sciences Campus
Los Angeles CA 90089-2821
Phone+1 424 240 9310
vCardDownload vCard

    Collapse Research 
    Collapse Research Activities and Funding
    GENETIC EPIDEMIOLOGY OF SCHIZOPHRENIA--5 HT AND NM
    NIH R01MH054232Sep 30, 1995 - Aug 31, 1998
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Investigating rare pathogenic/likely pathogenic exonic variation in bipolar disorder. Mol Psychiatry. 2021 Jan 22. Jia X, Goes FS, Locke AE, Palmer D, Wang W, Cohen-Woods S, Genovese G, Jackson AU, Jiang C, Kvale M, Mullins N, Nguyen H, Pirooznia M, Rivera M, Ruderfer DM, Shen L, Thai K, Zawistowski M, Zhuang Y, Abecasis G, Akil H, Bergen S, Burmeister M, Champion S, DelaBastide M, Juréus A, Kang HM, Kwok PY, Li JZ, Levy SE, Monson ET, Moran J, Sobell J, Watson S, Willour V, Zöllner S, Adolfsson R, Blackwood D, Boehnke M, Breen G, Corvin A, Craddock N, DiFlorio A, Hultman CM, Landen M, Lewis C, McCarroll SA, Richard McCombie W, McGuffin P, McIntosh A, McQuillin A, Morris D, Myers RM, O'Donovan M, Ophoff R, Boks M, Kahn R, Ouwehand W, Owen M, Pato C, Pato M, Posthuma D, Potash JB, Reif A, Sklar P, Smoller J, Sullivan PF, Vincent J, Walters J, Neale B, Purcell S, Risch N, Schaefer C, Stahl EA, Zandi PP, Scott LJ. PMID: 33483695.
      View in: PubMed   Mentions:    Fields:    
    2. Gene Expression in Patient-Derived Neural Progenitors Implicates WNT5A Signaling in the Etiology of Schizophrenia. Biol Psychiatry. 2020 Aug 01; 88(3):236-247. Evgrafov OV, Armoskus C, Wrobel BB, Spitsyna VN, Souaiaia T, Herstein JS, Walker CP, Nguyen JD, Camarena A, Weitz JR, Kim JMH, Lopez Duarte E, Wang K, Simpson GM, Sobell JL, Medeiros H, Pato MT, Pato CN, Knowles JA. PMID: 32143829.
      View in: PubMed   Mentions:    Fields:    
    3. Contributions of common genetic variants to risk of schizophrenia among individuals of African and Latino ancestry. Mol Psychiatry. 2020 10; 25(10):2455-2467. Bigdeli TB, Genovese G, Georgakopoulos P, Meyers JL, Peterson RE, Iyegbe CO, Medeiros H, Valderrama J, Achtyes ED, Kotov R, Stahl EA, Abbott C, Azevedo MH, Belliveau RA, Bevilacqua E, Bromet EJ, Byerley W, Carvalho CB, Chapman SB, DeLisi LE, Dumont AL, O'Dushlaine C, Evgrafov OV, Fochtmann LJ, Gage D, Kennedy JL, Kinkead B, Macedo A, Moran JL, Morley CP, Dewan MJ, Nemesh J, Perkins DO, Purcell SM, Rakofsky JJ, Scolnick EM, Sklar BM, Sklar P, Smoller JW, Sullivan PF, Macciardi F, Marder SR, Gur RC, Gur RE, Braff DL, Nicolini H, Escamilla MA, Vawter MP, Sobell JL, Malaspina D, Lehrer DS, Buckley PF, Rapaport MH, Knowles JA, Fanous AH, Pato MT, McCarroll SA, Pato CN. PMID: 31591465.
      View in: PubMed   Mentions: 6     Fields:    
    4. Genome-wide association study identifies 30 loci associated with bipolar disorder. Nat Genet. 2019 05; 51(5):793-803. Stahl EA, Breen G, Forstner AJ, McQuillin A, Ripke S, Trubetskoy V, Mattheisen M, Wang Y, Coleman JRI, Gaspar HA, de Leeuw CA, Steinberg S, Pavlides JMW, Trzaskowski M, Byrne EM, Pers TH, Holmans PA, Richards AL, Abbott L, Agerbo E, Akil H, Albani D, Alliey-Rodriguez N, Als TD, Anjorin A, Antilla V, Awasthi S, Badner JA, Bækvad-Hansen M, Barchas JD, Bass N, Bauer M, Belliveau R, Bergen SE, Pedersen CB, Bøen E, Boks MP, Boocock J, Budde M, Bunney W, Burmeister M, Bybjerg-Grauholm J, Byerley W, Casas M, Cerrato F, Cervantes P, Chambert K, Charney AW, Chen D, Churchhouse C, Clarke TK, Coryell W, Craig DW, Cruceanu C, Curtis D, Czerski PM, Dale AM, de Jong S, Degenhardt F, Del-Favero J, DePaulo JR, Djurovic S, Dobbyn AL, Dumont A, Elvsåshagen T, Escott-Price V, Fan CC, Fischer SB, Flickinger M, Foroud TM, Forty L, Frank J, Fraser C, Freimer NB, Frisén L, Gade K, Gage D, Garnham J, Giambartolomei C, Pedersen MG, Goldstein J, Gordon SD, Gordon-Smith K, Green EK, Green MJ, Greenwood TA, Grove J, Guan W, Guzman-Parra J, Hamshere ML, Hautzinger M, Heilbronner U, Herms S, Hipolito M, Hoffmann P, Holland D, Huckins L, Jamain S, Johnson JS, Juréus A, Kandaswamy R, Karlsson R, Kennedy JL, Kittel-Schneider S, Knowles JA, Kogevinas M, Koller AC, Kupka R, Lavebratt C, Lawrence J, Lawson WB, Leber M, Lee PH, Levy SE, Li JZ, Liu C, Lucae S, Maaser A, MacIntyre DJ, Mahon PB, Maier W, Martinsson L, McCarroll S, McGuffin P, McInnis MG, McKay JD, Medeiros H, Medland SE, Meng F, Milani L, Montgomery GW, Morris DW, Mühleisen TW, Mullins N, Nguyen H, Nievergelt CM, Adolfsson AN, Nwulia EA, O'Donovan C, Loohuis LMO, Ori APS, Oruc L, Ösby U, Perlis RH, Perry A, Pfennig A, Potash JB, Purcell SM, Regeer EJ, Reif A, Reinbold CS, Rice JP, Rivas F, Rivera M, Roussos P, Ruderfer DM, Ryu E, Sánchez-Mora C, Schatzberg AF, Scheftner WA, Schork NJ, Shannon Weickert C, Shehktman T, Shilling PD, Sigurdsson E, Slaney C, Smeland OB, Sobell JL, Søholm Hansen C, Spijker AT, St Clair D, Steffens M, Strauss JS, Streit F, Strohmaier J, Szelinger S, Thompson RC, Thorgeirsson TE, Treutlein J, Vedder H, Wang W, Watson SJ, Weickert TW, Witt SH, Xi S, Xu W, Young AH, Zandi P, Zhang P, Zöllner S, Adolfsson R, Agartz I, Alda M, Backlund L, Baune BT, Bellivier F, Berrettini WH, Biernacka JM, Blackwood DHR, Boehnke M, Børglum AD, Corvin A, Craddock N, Daly MJ, Dannlowski U, Esko T, Etain B, Frye M, Fullerton JM, Gershon ES, Gill M, Goes F, Grigoroiu-Serbanescu M, Hauser J, Hougaard DM, Hultman CM, Jones I, Jones LA, Kahn RS, Kirov G, Landén M, Leboyer M, Lewis CM, Li QS, Lissowska J, Martin NG, Mayoral F, McElroy SL, McIntosh AM, McMahon FJ, Melle I, Metspalu A, Mitchell PB, Morken G, Mors O, Mortensen PB, Müller-Myhsok B, Myers RM, Neale BM, Nimgaonkar V, Nordentoft M, Nöthen MM, O'Donovan MC, Oedegaard KJ, Owen MJ, Paciga SA, Pato C, Pato MT, Posthuma D, Ramos-Quiroga JA, Ribasés M, Rietschel M, Rouleau GA, Schalling M, Schofield PR, Schulze TG, Serretti A, Smoller JW, Stefansson H, Stefansson K, Stordal E, Sullivan PF, Turecki G, Vaaler AE, Vieta E, Vincent JB, Werge T, Nurnberger JI, Wray NR, Di Florio A, Edenberg HJ, Cichon S, Ophoff RA, Scott LJ, Andreassen OA, Kelsoe J, Sklar P. PMID: 31043756.
      View in: PubMed   Mentions: 103     Fields:    Translation:Humans
    5. Genome-wide Burden of Rare Short Deletions Is Enriched in Major Depressive Disorder in Four Cohorts. Biol Psychiatry. 2019 06 15; 85(12):1065-1073. Zhang X, Abdellaoui A, Rucker J, de Jong S, Potash JB, Weissman MM, Shi J, Knowles JA, Pato C, Pato M, Sobell J, Smit JH, Hottenga JJ, de Geus EJC, Lewis CM, Buttenschøn HN, Craddock N, Jones I, Jones L, McGuffin P, Mors O, Owen MJ, Preisig M, Rietschel M, Rice JP, Rivera M, Uher R, Gejman PV, Sanders AR, Boomsma D, Penninx BWJH, Breen G, Levinson DF. PMID: 31003785.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. Contribution of Rare Copy Number Variants to Bipolar Disorder Risk Is Limited to Schizoaffective Cases. Biol Psychiatry. 2019 07 15; 86(2):110-119. Charney AW, Stahl EA, Green EK, Chen CY, Moran JL, Chambert K, Belliveau RA, Forty L, Gordon-Smith K, Lee PH, Bromet EJ, Buckley PF, Escamilla MA, Fanous AH, Fochtmann LJ, Lehrer DS, Malaspina D, Marder SR, Morley CP, Nicolini H, Perkins DO, Rakofsky JJ, Rapaport MH, Medeiros H, Sobell JL, Backlund L, Bergen SE, Juréus A, Schalling M, Lichtenstein P, Knowles JA, Burdick KE, Jones I, Jones LA, Hultman CM, Perlis R, Purcell SM, McCarroll SA, Pato CN, Pato MT, Di Florio A, Craddock N, Landén M, Smoller JW, Ruderfer DM, Sklar P. PMID: 30686506.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    7. Evidence for genetic heterogeneity between clinical subtypes of bipolar disorder. Transl Psychiatry. 2017 01 10; 7(1):e993. PMID: 28072414.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    8. Association of DNA Methylation Differences With Schizophrenia in an Epigenome-Wide Association Study. JAMA Psychiatry. 2016 05 01; 73(5):506-14. PMID: 27074206.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    9. LINE1 insertions as a genomic risk factor for schizophrenia: Preliminary evidence from an affected family. . 2016 06; 171(4):534-45. PMID: 26990047.
      View in: PubMed   Mentions:
    10. Substance use associated with short sleep duration in patients with schizophrenia or schizoaffective disorder. . 2016 06; 171(4):525-33. PMID: 26345478.
      View in: PubMed   Mentions:
    11. Traumatic brain injury and bipolar psychosis in the Genomic Psychiatry Cohort. . 2016 06; 171(4):506-12. PMID: 26224022.
      View in: PubMed   Mentions:
    12. Paternal age effect: Replication in schizophrenia with intriguing dissociation between bipolar with and without psychosis. . 2016 06; 171(4):495-505. PMID: 26183902.
      View in: PubMed   Mentions:
    13. Comorbidity of severe psychotic disorders with measures of substance use. JAMA Psychiatry. 2014 Mar; 71(3):248-54. PMID: 24382686.
      View in: PubMed   Mentions: 62     Fields:    Translation:Humans
    14. Transposable elements and psychiatric disorders. . 2014 Apr; 165B(3):201-16. PMID: 24585726.
      View in: PubMed   Mentions:
    15. The genomic psychiatry cohort: partners in discovery. . 2013 Jun; 162B(4):306-12. PMID: 23650244.
      View in: PubMed   Mentions:
    16. A system architecture for sharing de-identified, research-ready brain scans and health information across clinical imaging centers. Stud Health Technol Inform. 2012; 175:19-28. PMID: 22941984.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    17. Evaluation of a susceptibility gene for schizophrenia: genotype based meta-analysis of RGS4 polymorphisms from thirteen independent samples. Biol Psychiatry. 2006 Jul 15; 60(2):152-62. Talkowski ME, Seltman H, Bassett AS, Brzustowicz LM, Chen X, Chowdari KV, Collier DA, Cordeiro Q, Corvin AP, Deshpande SN, Egan MF, Gill M, Kendler KS, Kirov G, Heston LL, Levitt P, Lewis DA, Li T, Mirnics K, Morris DW, Norton N, O'Donovan MC, Owen MJ, Richard C, Semwal P, Sobell JL, St Clair D, Straub RE, Thelma BK, Vallada H, Weinberger DR, Williams NM, Wood J, Zhang F, Devlin B, Nimgaonkar VL. PMID: 16631129.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    18. Failure to confirm association between RGS4 haplotypes and schizophrenia in Caucasians. . 2005 Nov 05; 139B(1):23-7. Sobell JL, Richard C, Wirshing DA, Heston LL. PMID: 16082709.
      View in: PubMed   Mentions:
    19. Multiple missense mutations in the diazepam binding inhibitor (DBI) gene identified in schizophrenia but lack of disease association. . 2004 Feb 15; 125B(1):10-9. Niu N, Rice SR, Heston LL, Sobell JL. PMID: 14755437.
      View in: PubMed   Mentions:
    20. Genetics and etiopathophysiology of schizophrenia. Mayo Clin Proc. 2002 Oct; 77(10):1068-82. Sobell JL, Mikesell MJ, McMurray CT. PMID: 12374251.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    21. Alteration of branch site consensus sequence and enhanced pre-mRNA splicing of an NMDAR1 intron not associated with schizophrenia. Am J Med Genet. 2002 Aug 08; 114(6):631-6. Hammond L, Castanotto D, Rice SR, Nimgaonkar VL, Wirshing DA, Rossi JJ, Heston LL, Sobell JL. PMID: 12210277.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    22. Identification of single nucleotide polymorphisms (SNPs) and other sequence changes and estimation of nucleotide diversity in coding and flanking regions of the NMDAR1 receptor gene in schizophrenic patients. Mol Psychiatry. 2001 May; 6(3):274-84. Rice SR, Niu N, Berman DB, Heston LL, Sobell JL. PMID: 11326295.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    23. Histamine N-methyltransferase functional polymorphism: lack of association with schizophrenia. Am J Med Genet. 2000 Jun 12; 96(3):404-6. Yan L, Szumlanski CL, Rice SR, Sobell JL, Lachman HM, Weinshilboum RM. PMID: 10898922.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    24. Variants in the alpha2A AR adrenergic receptor gene in psychiatric patients. Am J Med Genet. 1998 Sep 07; 81(5):405-10. Feng J, Sobell JL, Heston LL, Goldman D, Cook E, Kranzler HR, Gelernter J, Sommer SS. PMID: 9754626.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    25. Scanning of the dopamine D1 and D5 receptor genes by REF in neuropsychiatric patients reveals a novel missense change at a highly conserved amino acid. Am J Med Genet. 1998 Mar 28; 81(2):172-8. Feng J, Sobell JL, Heston LL, Cook EH, Goldman D, Sommer SS. PMID: 9613858.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    26. Gly(247)-->Asp proenkephalin A mutation is rare in schizophrenia populations. Am J Med Genet. 1997 Apr 18; 74(2):213-5. Mikesell MJ, Barron YD, Nimgaonkar VL, Sobell JL, Sommer SS, McMurray CT. PMID: 9129728.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    27. Screening the monoamine oxidase B gene in 100 male patients with schizophrenia: a cluster of polymorphisms in African-Americans but lack of functionally significant sequence changes. Am J Med Genet. 1997 Feb 21; 74(1):44-9. Sobell JL, Lind TJ, Hebrink DD, Heston LL, Sommer SS. PMID: 9034005.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    28. Identification of a missense mutation and several polymorphisms in the proenkephalin A gene of schizophrenic patients. Am J Med Genet. 1996 Sep 20; 67(5):459-67. Mikesell MJ, Sobell JL, Sommer SS, McMurray CT. PMID: 8886162.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    29. Genotype-to-phenotype analysis: search for clinical characteristics of a missense change in the GABAA-beta 1 receptor gene. Am J Med Genet. 1996 Feb 16; 67(1):81-4. Sobell JL, Sigurdson DC, Heston LL, Byerley WF, Sommer SS. PMID: 8678120.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    30. Screening the dopamine D1 receptor gene in 131 schizophrenics and eight alcoholics: identification of polymorphisms but lack of functionally significant sequence changes. Am J Med Genet. 1995 Apr 24; 60(2):165-71. Liu Q, Sobell JL, Heston LL, Sommer SS. PMID: 7485254.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    31. The D5 dopamine receptor gene in schizophrenia: identification of a nonsense change and multiple missense changes but lack of association with disease. Hum Mol Genet. 1995 Apr; 4(4):507-14. Sobell JL, Lind TJ, Sigurdson DC, Zald DH, Snitz BE, Grove WM, Heston LL, Sommer SS. PMID: 7633397.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    32. S311C D2DR variant: no association with schizophrenia. Lancet. 1994 Aug 27; 344(8922):621-2. Sobell J, Sigurdson DC, Heston L, Sommer S. PMID: 7914994.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    33. Screening the dystrophin gene suggests a high rate of polymorphism in general but no exonic deletions in schizophrenics. Am J Med Genet. 1994 Mar 15; 54(1):1-4. Lindor NM, Sobell JL, Heston LL, Thibodeau SN, Sommer SS. PMID: 7909988.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    34. Search for mutations in the beta 1 GABAA receptor subunit gene in patients with schizophrenia. Am J Med Genet. 1994 Mar 15; 54(1):12-20. Coon H, Sobell J, Heston L, Sommer S, Hoff M, Holik J, Umar F, Robertson M, Reimherr F, Wender P. PMID: 8178835.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    35. A common exonic polymorphism in the human D5 dopamine receptor gene. Hum Genet. 1993 Dec; 92(6):633-4. Sommer SS, Sobell JL, Heston LL. PMID: 8262527.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    36. APP mutations and schizophrenia. Biol Psychiatry. 1993 Nov 15; 34(10):739-40. Arnholt JC, Sobell JL, Heston LL, Sommer SS. PMID: 8292675.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    37. Dopamine D4 receptor variants in unrelated schizophrenic cases and controls. Am J Med Genet. 1993 Jul 15; 48(2):90-3. Sommer SS, Lind TJ, Heston LL, Sobell JL. PMID: 8103294.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    38. Novel association approach for determining the genetic predisposition to schizophrenia: case-control resource and testing of a candidate gene. Am J Med Genet. 1993 May 01; 48(1):28-35. Sobell JL, Heston LL, Sommer SS. PMID: 8357034.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    39. Eight novel polymorphisms in the dystrophin gene of African-Americans: the rate of polymorphism is high. Hum Mutat. 1993; 2(6):485-8. Lindor NM, Sommer SS, Sobell J, Heston L, Thibodeau SN. PMID: 7906594.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    40. Delineation of genetic predisposition to multifactorial disease: a general approach on the threshold of feasibility. Genomics. 1992 Jan; 12(1):1-6. Sobell JL, Heston LL, Sommer SS. PMID: 1733846.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    41. Direct sequencing of the dopamine D2 receptor (DRD2) in schizophrenics reveals three polymorphisms but no structural change in the receptor. Genomics. 1991 Sep; 11(1):8-14. Sarkar G, Kapelner S, Grandy DK, Marchionni M, Civelli O, Sobell J, Heston L, Sommer SS. PMID: 1837284.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    42. A novel method for detecting point mutations or polymorphisms and its application to population screening for carriers of phenylketonuria. Mayo Clin Proc. 1989 Nov; 64(11):1361-72. Sommer SS, Cassady JD, Sobell JL, Bottema CD. PMID: 2687596.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    43. Application of DNA-based diagnosis to patient care: the example of hemophilia A. Mayo Clin Proc. 1987 May; 62(5):387-404. Sommer SS, Sobell JL. PMID: 3553754.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    Janet's Networks
    Concepts (181)
    Derived automatically from this person's publications.
    Explore
    _
    Co-Authors (20)
    People in Profiles who have published with this person.
    Explore
    _
    Similar People (60)
    People who share similar concepts with this person.
    Explore
    _
    Same Department
    Search Department
    _
    ↑