Zhiheng He

Title(s)Assistant Professor of Molecular Microbiology and Immunology
SchoolKeck School of Medicine of Usc
Phone+1 323 865 0657
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Decoding the mosaic of inflammatory bowel disease: Illuminating insights with single-cell RNA technology. Comput Struct Biotechnol J. 2024 Dec; 23:2911-2923. Liu L, Davidorf B, Dong P, Peng A, Song Q, He Z. PMID: 39421242; PMCID: PMC11485491.
      View in: PubMed   Mentions:
    2. Distinct inflammatory Th17 subsets emerge in autoimmunity and infection. J Exp Med. 2023 10 02; 220(10). Bouch RJ, Zhang J, Miller BC, Robbins CJ, Mosher TH, Li W, Krupenko SA, Nagpal R, Zhao J, Bloomfeld RS, Lu Y, Nikiforov MA, Song Q, He Z. PMID: 37367944; PMCID: PMC10300431.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    3. Decoupling the role of RORγt in the differentiation and effector function of TH17 cells. Sci Adv. 2022 Oct 21; 8(42):eadc9221. Zhong X, Wu H, Zhang W, Gwack Y, Shang W, Lee KO, Isakov N, He Z, Sun Z. PMID: 36269826; PMCID: PMC9586477.
      View in: PubMed   Mentions: 1     Fields:    
    4. Correction: Oncogenic Herpesvirus KSHV Hijacks BMP-Smad1-Id Signaling to Promote Tumorigenesis. PLoS Pathog. 2022 Mar; 18(3):e1010390. Liang D, Hu H, Li S, Dong J, Wang X, Wang Y, He L, He Z, Gao Y, Gao SJ, Lan K. PMID: 35286345; PMCID: PMC8920289.
      View in: PubMed   Mentions: 1     Fields:    
    5. USP19 Suppresses Th17-Driven Pathogenesis in Autoimmunity. J Immunol. 2021 07 01; 207(1):23-33. Zhang J, Bouch RJ, Blekhman MG, He Z. PMID: 34135062; PMCID: PMC8674369.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    6. Correction: PRMT1 Plays a Critical Role in Th17 Differentiation by Regulating Reciprocal Recruitment of STAT3 and STAT5. J Immunol. 2019 Oct 01; 203(7):2021-2022. Sen S, He Z, Ghosh S, Dery KJ, Yang L, Zhang J, Sun Z. PMID: 31462503.
      View in: PubMed   Mentions:    Fields:    
    7. SRC3 Is a Cofactor for RORγt in Th17 Differentiation but Not Thymocyte Development. J Immunol. 2019 02 01; 202(3):760-769. He Z, Zhang J, Du Q, Xu J, Gwack Y, Sun Z. PMID: 30567733; PMCID: PMC6344289.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    8. Sumoylation of RORγt regulates TH17 differentiation and thymocyte development. Nat Commun. 2018 11 19; 9(1):4870. He Z, Zhang J, Huang Z, Du Q, Li N, Zhang Q, Chen Y, Sun Z. PMID: 30451821; PMCID: PMC6242824.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    9. PRMT1 Plays a Critical Role in Th17 Differentiation by Regulating Reciprocal Recruitment of STAT3 and STAT5. J Immunol. 2018 07 15; 201(2):440-450. Sen S, He Z, Ghosh S, Dery KJ, Yang L, Zhang J, Sun Z. PMID: 29794014; PMCID: PMC6039255.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    10. TCF-1 Inhibits IL-17 Gene Expression To Restrain Th17 Immunity in a Stage-Specific Manner. J Immunol. 2018 05 15; 200(10):3397-3406. Zhang J, He Z, Sen S, Wang F, Zhang Q, Sun Z. PMID: 29632143; PMCID: PMC5940498.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    11. SRC1 promotes Th17 differentiation by overriding Foxp3 suppression to stimulate RORγt activity in a PKC-θ-dependent manner. Proc Natl Acad Sci U S A. 2018 01 16; 115(3):E458-E467. Sen S, Wang F, Zhang J, He Z, Ma J, Gwack Y, Xu J, Sun Z. PMID: 29282318; PMCID: PMC5776998.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    12. A two-amino-acid substitution in the transcription factor RORγt disrupts its function in TH17 differentiation but not in thymocyte development. Nat Immunol. 2017 Oct; 18(10):1128-1138. He Z, Ma J, Wang R, Zhang J, Huang Z, Wang F, Sen S, Rothenberg EV, Sun Z. PMID: 28846085; PMCID: PMC5678981.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    13. Regulation of Th17 Differentiation by IKKα-Dependent and -Independent Phosphorylation of RORγt. J Immunol. 2017 08 01; 199(3):955-964. He Z, Wang F, Zhang J, Sen S, Pang Q, Luo S, Gwack Y, Sun Z. PMID: 28667162; PMCID: PMC5531059.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    14. Fine-Tuning of the Kaposi's Sarcoma-Associated Herpesvirus Life Cycle in Neighboring Cells through the RTA-JAG1-Notch Pathway. PLoS Pathog. 2016 Oct; 12(10):e1005900. Li S, Hu H, He Z, Liang D, Sun R, Lan K. PMID: 27760204; PMCID: PMC5070770.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    15. Ubiquitination of RORγt at Lysine 446 Limits Th17 Differentiation by Controlling Coactivator Recruitment. J Immunol. 2016 08 15; 197(4):1148-58. He Z, Wang F, Ma J, Sen S, Zhang J, Gwack Y, Zhou Y, Sun Z. PMID: 27430721; PMCID: PMC4976012.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    16. Oncogenic herpesvirus KSHV Hijacks BMP-Smad1-Id signaling to promote tumorigenesis. PLoS Pathog. 2014 Jul; 10(7):e1004253. Liang D, Hu H, Li S, Dong J, Wang X, Wang Y, He L, He Z, Gao Y, Gao SJ, Lan K. PMID: 25010525; PMCID: PMC4092152.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    17. Latency-associated nuclear antigen of Kaposi sarcoma-associated herpesvirus promotes angiogenesis through targeting notch signaling effector Hey1. Cancer Res. 2014 Apr 01; 74(7):2026-37. Wang X, He Z, Xia T, Li X, Liang D, Lin X, Wen H, Lan K. PMID: 24523441.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    18. NF-κB activation coordinated by IKKβ and IKKε enables latent infection of Kaposi's sarcoma-associated herpesvirus. J Virol. 2014 Jan; 88(1):444-55. He Z, Zhao J, Zhang J, Jung JU, Feng P. PMID: 24155403; PMCID: PMC3911695.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    19. Carboxyl-terminal amino acids 1052 to 1082 of the latency-associated nuclear antigen (LANA) interact with RBP-Jκ and are responsible for LANA-mediated RTA repression. J Virol. 2012 May; 86(9):4956-69. Jin Y, He Z, Liang D, Zhang Q, Zhang H, Deng Q, Robertson ES, Lan K. PMID: 22379075; PMCID: PMC3347342.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    20. miR-K12-7-5p encoded by Kaposi's sarcoma-associated herpesvirus stabilizes the latent state by targeting viral ORF50/RTA. PLoS One. 2011 Jan 20; 6(1):e16224. Lin X, Liang D, He Z, Deng Q, Robertson ES, Lan K. PMID: 21283761; PMCID: PMC3024408.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansCells
    21. A human herpesvirus miRNA attenuates interferon signaling and contributes to maintenance of viral latency by targeting IKKε. Cell Res. 2011 May; 21(5):793-806. Liang D, Gao Y, Lin X, He Z, Zhao Q, Deng Q, Lan K. PMID: 21221132; PMCID: PMC3325102.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansAnimalsCells
    22. Cellular corepressor TLE2 inhibits replication-and-transcription- activator-mediated transactivation and lytic reactivation of Kaposi's sarcoma-associated herpesvirus. J Virol. 2010 Feb; 84(4):2047-62. He Z, Liu Y, Liang D, Wang Z, Robertson ES, Lan K. PMID: 19939918; PMCID: PMC2812399.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    23. Inhibition of KSHV-infected primary effusion lymphomas in NOD/SCID mice by gamma-secretase inhibitor. Cancer Biol Ther. 2009 Nov; 8(22):2136-43. Lan K, Murakami M, Bajaj B, Kaul R, He Z, Gan R, Feldman M, Robertson ES. PMID: 19783901; PMCID: PMC5965683.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
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    NIH Funding Acknowledgment: Important - All publications resulting from the utilization of SC CTSI resources are required to credit the SC CTSI grant by including the NIH funding acknowledgment and must comply with the NIH Public Access Policy.

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