Tina Jaskoll, BA, PhD

SchoolHerman Ostrow School of Dentistry of USC
Phone+1 213 740 1400
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    Collapse Research 
    Collapse Research Activities and Funding
    CMV-Induced Embryonic Cochlear Pathogenesis
    NIH/NIDCD R21DC010424Dec 4, 2009 - Nov 30, 2013
    Role: Principal Investigator
    Eda/Edar Regulation of Embryonic SMG Development
    NIH/NIDCR R01DE014535Jul 1, 2003 - Jun 30, 2010
    Role: Principal Investigator
    NIH/NIDCR R01DE011942Sep 30, 1996 - Jul 31, 2003
    Role: Principal Investigator
    NIH/NIDCR R01DE010376Jul 1, 1993 - Jun 30, 1999
    Role: Principal Investigator
    NIH/NIDCR R01DE008190Aug 1, 1988 - Jul 31, 1992
    Role: Principal Investigator
    NIH/NHLBI R01HL041477Apr 1, 1988 - Mar 31, 1993
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Melnick M, Jaskoll T. CMV-induced embryonic mouse organ of corti dysplasia: Network architecture of dysfunctional lateral inhibition. Birth Defects Res A Clin Mol Teratol. 2015 Jul; 103(7):573-82. PMID: 26178632; PMCID: PMC4509978.
    2. Melnick M, Deluca KA, Jaskoll T. CMV-induced pathology: pathway and gene-gene interaction analysis. Exp Mol Pathol. 2014 Aug; 97(1):154-65. PMID: 24984270.
      View in: PubMed
    3. Melnick M, Deluca KA, Sedghizadeh PP, Jaskoll T. Cytomegalovirus-induced salivary gland pathology: AREG, FGF8, TNF-a, and IL-6 signal dysregulation and neoplasia. Exp Mol Pathol. 2013 Apr; 94(2):386-97. PMID: 23399805.
      View in: PubMed
    4. Melnick M, Sedghizadeh PP, Deluca KA, Jaskoll T. Cytomegalovirus-induced salivary gland pathology: resistance to kinase inhibitors of the upregulated host cell EGFR/ERK pathway is associated with CMV-dependent stromal overexpression of IL-6 and fibronectin. Herpesviridae. 2013 Jan 23; 4(1):1. PMID: 23342981; PMCID: PMC3602079.
    5. Melnick M, Jaskoll T. An in vitro mouse model of congenital cytomegalovirus-induced pathogenesis of the inner ear cochlea. Birth Defects Res A Clin Mol Teratol. 2013 Feb; 97(2):69-78. PMID: 23281115; PMCID: PMC4476032.
    6. Melnick M, Sedghizadeh PP, Allen CM, Jaskoll T. Human cytomegalovirus and mucoepidermoid carcinoma of salivary glands: cell-specific localization of active viral and oncogenic signaling proteins is confirmatory of a causal relationship. Exp Mol Pathol. 2012 Feb; 92(1):118-25. PMID: 22101257.
      View in: PubMed
    7. Billington CJ, Fiebig JE, Forsman CL, Pham L, Burbach N, Sun M, Jaskoll T, Mansky K, Gopalakrishnan R, O'Connor MB, Mueller TD, Petryk A. Glycosylation of Twisted Gastrulation is Required for BMP Binding and Activity during Craniofacial Development. Front Physiol. 2011; 2:59. PMID: 21941513; PMCID: PMC3170884.
    8. Melnick M, Abichaker G, Htet K, Sedghizadeh P, Jaskoll T. Small molecule inhibitors of the host cell COX/AREG/EGFR/ERK pathway attenuate cytomegalovirus-induced pathogenesis. Exp Mol Pathol. 2011 Aug; 91(1):400-10. PMID: 21565184; PMCID: PMC3139723.
    9. Jaskoll T, Htet K, Abichaker G, Kaye FJ, Melnick M. CRTC1 expression during normal and abnormal salivary gland development supports a precursor cell origin for mucoepidermoid cancer. Gene Expr Patterns. 2011 Jan-Feb; 11(1-2):57-63. PMID: 20837164; PMCID: PMC3033996.
    10. Jaskoll T, Abichaker G, Htet K, Bringas P, Morita S, Sedghizadeh PP, Melnick M. Cytomegalovirus induces stage-dependent enamel defects and misexpression of amelogenin, enamelin and dentin sialophosphoprotein in developing mouse molars. Cells Tissues Organs. 2010; 192(4):221-39. PMID: 20484882.
      View in: PubMed
    11. Melnick M, Phair RD, Lapidot SA, Jaskoll T. Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009 Jun 06; 9:32. PMID: 19500387; PMCID: PMC2700095.
    12. Jaskoll T, Abichaker G, Sedghizadeh PP, Bringas P, Melnick M. Cytomegalovirus induces abnormal chondrogenesis and osteogenesis during embryonic mandibular development. BMC Dev Biol. 2008 Mar 27; 8:33. PMID: 18371224; PMCID: PMC2330031.
    13. Jaskoll T, Abichaker G, Jangaard N, Bringas P, Melnick M. Cytomegalovirus inhibition of embryonic mouse tooth development: a model of the human amelogenesis imperfecta phenocopy. Arch Oral Biol. 2008 May; 53(5):405-15. PMID: 18201685; PMCID: PMC2279100.
    14. Melnick M, Mocarski ES, Abichaker G, Huang J, Jaskoll T. Cytomegalovirus-induced embryopathology: mouse submandibular salivary gland epithelial-mesenchymal ontogeny as a model. BMC Dev Biol. 2006 Sep 07; 6:42. PMID: 16959038; PMCID: PMC1601957.
    15. Melnick M, Petryk A, Abichaker G, Witcher D, Person AD, Jaskoll T. Embryonic salivary gland dysmorphogenesis in Twisted gastrulation deficient mice. Arch Oral Biol. 2006 May; 51(5):433-8. PMID: 16289463; PMCID: PMC1440928.
    16. Jaskoll T, Abichaker G, Witcher D, Sala FG, Bellusci S, Hajihosseini MK, Melnick M. FGF10/FGFR2b signaling plays essential roles during in vivo embryonic submandibular salivary gland morphogenesis. BMC Dev Biol. 2005 Jun 22; 5:11. PMID: 15972105; PMCID: PMC1184065.
    17. Melnick M, Witcher D, Bringas P, Carlsson P, Jaskoll T. Meckel's cartilage differentiation is dependent on hedgehog signaling. Cells Tissues Organs. 2005; 179(4):146-57. PMID: 16046861.
      View in: PubMed
    18. Jaskoll T, Witcher D, Toreno L, Bringas P, Moon AM, Melnick M. FGF8 dose-dependent regulation of embryonic submandibular salivary gland morphogenesis. Dev Biol. 2004 Apr 15; 268(2):457-69. PMID: 15063181.
      View in: PubMed
    19. Jaskoll T, Leo T, Witcher D, Ormestad M, Astorga J, Bringas P, Carlsson P, Melnick M. Sonic hedgehog signaling plays an essential role during embryonic salivary gland epithelial branching morphogenesis. Dev Dyn. 2004 Apr; 229(4):722-32. PMID: 15042696.
      View in: PubMed
    20. Jaskoll T, Zhou YM, Trump G, Melnick M. Ectodysplasin receptor-mediated signaling is essential for embryonic submandibular salivary gland development. Anat Rec A Discov Mol Cell Evol Biol. 2003 Apr; 271(2):322-31. PMID: 12629675.
      View in: PubMed
    21. Jaskoll T, Zhou YM, Chai Y, Makarenkova HP, Collinson JM, West JD, Hajihosseini MK, Lee J, Melnick M. Embryonic submandibular gland morphogenesis: stage-specific protein localization of FGFs, BMPs, Pax6 and Pax9 in normal mice and abnormal SMG phenotypes in FgfR2-IIIc(+/Delta), BMP7(-/-) and Pax6(-/-) mice. Cells Tissues Organs. 2002; 170(2-3):83-98. PMID: 11731698.
      View in: PubMed
    22. Hu CC, Jaskoll TF, Minkin C, Melnick M. Mouse major histocompatibility complex (H-2) and fetal lung development: implications for human pulmonary maturation. Am J Med Genet. 1990 Jan; 35(1):126-31. PMID: 2301462.
      View in: PubMed
    23. Jaskoll TF, Don-Wheeler G, Johnson R, Slavkin HC. Embryonic mouse lung morphogenesis and type II cytodifferentiation in serumless, chemically defined medium using prolonged in vitro cultures. Cell Differ. 1988 Jul; 24(2):105-17. PMID: 3061659.
      View in: PubMed
    24. Slavkin HC, Jaskoll TF, MacDougall M, Zeichner-David M. Hormonal and non-hormonal features of selected epithelial-mesenchymal interactions during development. Prog Clin Biol Res. 1986; 226:93-102. PMID: 3543971.
      View in: PubMed
    25. Slavkin HC, Snead ML, Zeichner-David M, Jaskoll TF, Smith BT. Concepts of epithelial-mesenchymal interactions during development: tooth and lung organogenesis. J Cell Biochem. 1984; 26(2):117-25. PMID: 6396310.
      View in: PubMed