David Z D'Argenio, PhD

Title(s)Professor
AddressDRB 154
University Park Campus
Los Angeles CA 90089-1111
Phone+1 213 740 0341
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    David Z. D'Argenio received his Bachelors degree in Electrical Engineering from the University of Dayton in 1972, M.S. in Electrical Engineering from the Pennsylvania State University in 1974, and Ph.D. in Biomedical Engineering from USC in 1979. From 1993 to 1995 he served as Associate Dean for Academic Affairs in the School of Engineering and from 1996 to 2003 as Chairman of the Department of Biomedical Engineering. He also served as Interim Director of the Alfred E. Mann Institute for Biomedical Engineering from 1998-1999. Professor D'Argenio also serves on the Board of Trustees of the House Ear Institute and currently serves as the Chair of the Board.

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    Biomedical Simulations Resource (BMSR)
    NIH P41EB001978Sep 30, 1997 - Aug 31, 2020
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A whole-body circulatory neutrophil model with application to predicting clinical neutropenia from in vitro studies. CPT Pharmacometrics Syst Pharmacol. 2021 Jul; 10(7):671-683. Chen W, Boras B, Sung T, Hu W, Spilker ME, D'Argenio DZ. PMID: 33793091.
      View in: PubMed   Mentions:    Fields:    
    2. Characteristics of Passive Solute Transport across Primary Rat Alveolar Epithelial Cell Monolayers. Membranes (Basel). 2021 Apr 30; 11(5). Kim YH, Kim KJ, D'Argenio DZ, Crandall ED. PMID: 33946241.
      View in: PubMed   Mentions:
    3. An Analysis of Glucose Effectiveness in Subjects With or Without Type 2 Diabetes via Hierarchical Modeling. Front Endocrinol (Lausanne). 2021; 12:641713. Hu S, Lu Y, Tura A, Pacini G, D'Argenio DZ. PMID: 33854483.
      View in: PubMed   Mentions:
    4. The Funnel: a Screening Technique for Identifying Optimal Two-Drug Combination Chemotherapy Regimens. Antimicrob Agents Chemother. 2021 01 20; 65(2). Drusano GL, Kim S, Almoslem M, Schmidt S, D'Argenio DZ, Myrick J, Duncanson B, Nole J, Brown D, Peloquin CA, Neely M, Yamada W, Louie A. PMID: 33199386.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    5. Population Pharmacokinetic Modeling of Vancomycin in Thai Patients With Heterogeneous and Unstable Renal Function. Ther Drug Monit. 2020 12; 42(6):856-865. Jaisue S, Pongsakul C, D'Argenio DZ, Sermsappasuk P. PMID: 32947558.
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    6. Predicting Chemotherapy-Induced Neutropenia and Granulocyte Colony-Stimulating Factor Response Using Model-Based In Vitro to Clinical Translation. AAPS J. 2020 11 06; 22(6):143. Chen W, Boras B, Sung T, Hu W, Spilker ME, D'Argenio DZ. PMID: 33156437.
      View in: PubMed   Mentions:    Fields:    
    7. Biokinetic modeling of nanoparticle interactions with lung alveolar epithelial cells: uptake, intracellular processing, and egress. Am J Physiol Regul Integr Comp Physiol. 2021 01 01; 320(1):R36-R43. Chen W, D'Argenio DZ, Sipos A, Kim KJ, Crandall ED. PMID: 33085912.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    8. The Efficiency, Efficacy, and Retention of Task Practice in Chronic Stroke. Neurorehabil Neural Repair. 2020 10; 34(10):881-890. Wang C, Winstein C, D'Argenio DZ, Schweighofer N. PMID: 32830617.
      View in: PubMed   Mentions: 2     Fields:    
    9. Predicting monoclonal antibody pharmacokinetics following subcutaneous administration via whole-body physiologically-based modeling. J Pharmacokinet Pharmacodyn. 2020 10; 47(5):385-409. Hu S, D'Argenio DZ. PMID: 32500362.
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    10. A physiological model of granulopoiesis to predict clinical drug induced neutropenia from in vitro bone marrow studies: with application to a cell cycle inhibitor. J Pharmacokinet Pharmacodyn. 2020 04; 47(2):163-182. Chen W, Boras B, Sung T, Yu Y, Zheng J, Wang D, Hu W, Spilker ME, D'Argenio DZ. PMID: 32162138.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    11. Analytical solution of linear multi-compartment models with non-zero initial condition and its implementation with R. Transl Clin Pharmacol. 2019 Jun; 27(2):43-51. D'Argenio DZ, Bae KS. PMID: 32055580.
      View in: PubMed   Mentions:
    12. Pharmacokinetics of Tedizolid in Plasma and Sputum of Adults with Cystic Fibrosis. Antimicrob Agents Chemother. 2018 09; 62(9). Park AYJ, Wang J, Jayne J, Fukushima L, Rao AP, D'Argenio DZ, Beringer PM. PMID: 29914949.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    13. Pharmacokinetic-Pharmacodynamic Target Attainment Analyses To Determine Optimal Dosing of Ceftazidime-Avibactam for the Treatment of Acute Pulmonary Exacerbations in Patients with Cystic Fibrosis. Antimicrob Agents Chemother. 2017 10; 61(10). Bensman TJ, Wang J, Jayne J, Fukushima L, Rao AP, D'Argenio DZ, Beringer PM. PMID: 28784670.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCellsCTClinical Trials
    14. Population-based meta-analysis of roxithromycin pharmacokinetics: dosing implications of saturable absorption and protein binding. J Antimicrob Chemother. 2017 04 01; 72(4):1129-1136. Dolton MJ, D'Argenio DZ. PMID: 28039274.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    15. RAD-ADAPT: Software for modelling clonogenic assay data in radiation biology. DNA Repair (Amst). 2017 04; 52:24-30. Zhang Y, Hu K, Beumer JH, Bakkenist CJ, D'Argenio DZ. PMID: 28254357.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    16. Reply to Scagnolari et al. J Infect Dis. 2017 02 01; 215(3):493-494. Brown AN, Gallegos KM, D'Argenio DZ, Drusano GL. PMID: 28003357.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    17. Glucagon increases insulin levels by stimulating insulin secretion without effect on insulin clearance in mice. Peptides. 2017 02; 88:74-79. Song G, Pacini G, Ahrén B, D'Argenio DZ. PMID: 28012858.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    18. Feedback control indirect response models. J Pharmacokinet Pharmacodyn. 2016 08; 43(4):343-58. Zhang Y, D'Argenio DZ. PMID: 27394724.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    19. Modeling Ribavirin-Induced Anemia in Patients with Chronic Hepatitis C Virus. CPT Pharmacometrics Syst Pharmacol. 2016 Feb; 5(2):65-73. Wu LS, Jimmerson LC, MacBrayne CE, Kiser JJ, D'Argenio DZ. PMID: 26933517.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    20. Human insulin dynamics in women: a physiologically based model. . 2016 Feb 01; 310(3):R268-74. Weiss M, Tura A, Kautzky-Willer A, Pacini G, D'Argenio DZ. PMID: 26608654.
      View in: PubMed   Mentions:
    21. Population pharmacokinetic modeling of plasma and intracellular ribavirin concentrations in patients with chronic hepatitis C virus infection. Antimicrob Agents Chemother. 2015 Apr; 59(4):2179-88. Wu LS, Rower JE, Burton JR, Anderson PL, Hammond KP, Baouchi-Mokrane F, Everson GT, Urban TJ, D'Argenio DZ, Kiser JJ. PMID: 25645847.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    22. FLT3 and CDK4/6 inhibitors: signaling mechanisms and tumor burden in subcutaneous and orthotopic mouse models of acute myeloid leukemia. J Pharmacokinet Pharmacodyn. 2014 Dec; 41(6):675-91. Zhang Y, Hsu CP, Lu JF, Kuchimanchi M, Sun YN, Ma J, Xu G, Zhang Y, Xu Y, Weidner M, Huard J, D'Argenio DZ. PMID: 25326874.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    23. Integrated population pharmacokinetic/viral dynamic modelling of lopinavir/ritonavir in HIV-1 treatment-naïve patients. Clin Pharmacokinet. 2014 Apr; 53(4):361-71. Wang K, D'Argenio DZ, Acosta EP, Sheth AN, Delille C, Lennox JL, Kerstner-Wood C, Ofotokun I. PMID: 24311282.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    24. Glucagon clearance is regulated by nutritional state: evidence from experimental studies in mice. Diabetologia. 2014 Apr; 57(4):801-8. Zhou A, Pacini G, Ahrén B, D'Argenio DZ. PMID: 24370975.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    25. Analysis of intravenous glucose tolerance test data using parametric and nonparametric modeling: application to a population at risk for diabetes. J Diabetes Sci Technol. 2013 Jul 01; 7(4):952-62. Marmarelis VZ, Shin DC, Zhang Y, Kautzky-Willer A, Pacini G, D'Argenio DZ. PMID: 23911176.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    26. Population-based efficacy modeling of omalizumab in patients with severe allergic asthma inadequately controlled with standard therapy. AAPS J. 2013 Apr; 15(2):559-70. Zhu R, Zheng Y, Putnam WS, Visich J, Eisner MD, Matthews JG, Rosen KE, D'Argenio DZ. PMID: 23413101.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    27. TARGETgene: a tool for identification of potential therapeutic targets in cancer. PLoS One. 2012; 7(8):e43305. Wu CC, D'Argenio D, Asgharzadeh S, Triche T. PMID: 22952662.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    28. Intracellular-signaling tumor-regression modeling of the pro-apoptotic receptor agonists dulanermin and conatumumab. J Pharmacokinet Pharmacodyn. 2012 Oct; 39(5):577-90. Kay BP, Hsu CP, Lu JF, Sun YN, Bai S, Xin Y, D'Argenio DZ. PMID: 22932917.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    29. Isoniazid pharmacokinetics, pharmacodynamics, and dosing in South African infants. Ther Drug Monit. 2012 Aug; 34(4):446-51. Kiser JJ, Zhu R, D'Argenio DZ, Cotton MF, Bobat R, McSherry GD, Madhi SA, Carey VJ, Seifart HI, Werely CJ, Fletcher CV. PMID: 22695364.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    30. Affiliation between the American Society of Pharmacometrics and the Journal of Pharmacokinetics and Pharmacodynamics. J Pharmacokinet Pharmacodyn. 2012 Feb; 39(1):3. D'Argenio DZ, Gastonguay MR, Brundage RC, Miller R, Tannenbaum SJ, Pfister M. PMID: 22219000.
      View in: PubMed   Mentions:    Fields:    
    31. A local effect of CYP24 inhibition on lung tumor xenograft exposure to 1,25-dihydroxyvitamin D(3) is revealed using a novel LC-MS/MS assay. Steroids. 2012 Apr; 77(5):477-83. Beumer JH, Parise RA, Kanterewicz B, Petkovich M, D'Argenio DZ, Hershberger PA. PMID: 22285938.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    32. Editorial: TBME Letters special issue on multiscale modeling and analysis in computational biology and medicine--part-2. IEEE Trans Biomed Eng. 2011 Dec; 58(12):3434-9. Coatrieux JL, Frangi AF, Peng GC, D'Argenio DZ, Marmarelis VZ, Michailova A. PMID: 22105190.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    33. Pharmacokinetics of doxycycline in adults with cystic fibrosis. Antimicrob Agents Chemother. 2012 Jan; 56(1):70-4. Beringer PM, Owens H, Nguyen A, Benitez D, Rao A, D'Argenio DZ. PMID: 22024822.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    34. Editorial: Special issue on multiscale modeling and analysis in computational biology and medicine--part-1. IEEE Trans Biomed Eng. 2011 Oct; 58(10):2936-42. Frangi AF, Coatrieux JL, Peng GC, D'Argenio DZ, Marmarelis VZ, Michailova A. PMID: 21937299.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    35. The pharmacogenetics of NAT2 enzyme maturation in perinatally HIV exposed infants receiving isoniazid. J Clin Pharmacol. 2012 Apr; 52(4):511-9. Zhu R, Kiser JJ, Seifart HI, Werely CJ, Mitchell CD, D'Argenio DZ, Fletcher CV. PMID: 21558457.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCTClinical Trials
    36. Effects of increasing doses of glucagon-like peptide-1 on insulin-releasing phases during intravenous glucose administration in mice. . 2011 May; 300(5):R1126-33. Chan HM, Jain R, Ahrén B, Pacini G, D'Argenio DZ. PMID: 21307364.
      View in: PubMed   Mentions:
    37. The emerging scientific discipline of pharmacometrics. J Clin Pharmacol. 2010 Sep; 50(9 Suppl):6S. Pfister M, D'Argenio DZ. PMID: 20881211.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    38. ACoP: the tools, carpenters, and architects building the discipline of pharmacometrics. J Clin Pharmacol. 2010 Sep; 50(9 Suppl):7S-8S. Brundage RC, Pfister M, D'Argenio DZ, Gastonguay MR, Miller R, Tannenbaum SJ. PMID: 20881212.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    39. Bridging pharmacology and pathophysiology via systems modeling. J Clin Pharmacol. 2010 Sep; 50(9 Suppl):56S-57S. D'Argenio DZ, Mager DE. PMID: 20881218.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    40. Defining the future of pharmacometrics: the American Society of Pharmacometrics. J Clin Pharmacol. 2010 Sep; 50(9 Suppl):158S. Pfister M, Brundage RC, Gastonguay MR, Miller R, Tannenbaum SJ, D'Argenio DZ. PMID: 20881230.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    41. Plasma pharmacokinetics and oral bioavailability of the 3,4,5,6-tetrahydrouridine (THU) prodrug, triacetyl-THU (taTHU), in mice. Cancer Chemother Pharmacol. 2011 Feb; 67(2):421-30. Beumer JH, Eiseman JL, Gilbert JA, Holleran JL, Yellow-Duke AE, Clausen DM, D'Argenio DZ, Ames MM, Hershberger PA, Parise RA, Bai L, Covey JM, Egorin MJ. PMID: 20443002.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    42. Prediction of human functional genetic networks from heterogeneous data using RVM-based ensemble learning. Bioinformatics. 2010 Mar 15; 26(6):807-13. Wu CC, Asgharzadeh S, Triche TJ, D'Argenio DZ. PMID: 20134029.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    43. Vitreous VEGF clearance is increased after vitrectomy. Invest Ophthalmol Vis Sci. 2010 Apr; 51(4):2135-8. Lee SS, Ghosn C, Yu Z, Zacharias LC, Kao H, Lanni C, Abdelfattah N, Kuppermann B, Csaky KG, D'Argenio DZ, Burke JA, Hughes PM, Robinson MR. PMID: 20019364.
      View in: PubMed   Mentions: 26     Fields:    Translation:Animals
    44. Population Pharmacokinetic/Pharmacodyanamic Mixture Models via Maximum a Posteriori Estimation. Comput Stat Data Anal. 2009 Oct 01; 53(12):3907-3915. Wang X, Schumitzky A, D'Argenio DZ. PMID: 20161085.
      View in: PubMed   Mentions:
    45. Synergy of karenitecin and mafosfamide in pediatric leukemia, medulloblastoma, and neuroblastoma cell lines. Pediatr Blood Cancer. 2008 Apr; 50(4):757-60. Jacob E, Scorsone K, Blaney SM, D'Argenio DZ, Berg SL. PMID: 17849472.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    46. A note on population analysis of dissolution-absorption models using the inverse Gaussian function. J Clin Pharmacol. 2008 Jun; 48(6):719-25. Wang J, Weiss M, D'Argenio DZ. PMID: 18359921.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    47. Plasma pharmacokinetics and oral bioavailability of 3,4,5,6-tetrahydrouridine, a cytidine deaminase inhibitor, in mice. Cancer Chemother Pharmacol. 2008 Aug; 62(3):457-64. Beumer JH, Eiseman JL, Parise RA, Florian JA, Joseph E, D'Argenio DZ, Parker RS, Kay B, Covey JM, Egorin MJ. PMID: 18008070.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    48. Nonlinear Random Effects Mixture Models: Maximum Likelihood Estimation via the EM Algorithm. Comput Stat Data Anal. 2007 Aug 15; 51(12):6614-6623. Wang X, Schumitzky A, D'Argenio DZ. PMID: 19756256.
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    49. A mass balance and disposition study of the DNA methyltransferase inhibitor zebularine (NSC 309132) and three of its metabolites in mice. Clin Cancer Res. 2006 Oct 01; 12(19):5826-33. Beumer JH, Joseph E, Egorin MJ, Parker RS, D'argenio DZ, Covey JM, Eiseman JL. PMID: 17020990.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    50. Model for intracellular Lamivudine metabolism in peripheral blood mononuclear cells ex vivo and in human immunodeficiency virus type 1-infected adolescents. Antimicrob Agents Chemother. 2006 Aug; 50(8):2686-94. Zhou Z, Rodman JH, Flynn PM, Robbins BL, Wilcox CK, D'Argenio DZ. PMID: 16870759.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCellsCTClinical Trials
    51. Bortezomib interactions with chemotherapy agents in acute leukemia in vitro. Cancer Chemother Pharmacol. 2006 Jul; 58(1):13-23. Horton TM, Gannavarapu A, Blaney SM, D'Argenio DZ, Plon SE, Berg SL. PMID: 16292537.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    52. Plasma pharmacokinetics, oral bioavailability, and interspecies scaling of the DNA methyltransferase inhibitor, zebularine. Clin Cancer Res. 2005 May 15; 11(10):3862-8. Holleran JL, Parise RA, Joseph E, Eiseman JL, Covey JM, Glaze ER, Lyubimov AV, Chen YF, D'Argenio DZ, Egorin MJ. PMID: 15897587.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    53. Kinetic modeling of 5-fluorouracil anabolism in colorectal adenocarcinoma: a positron emission tomography study in rats. Cancer Res. 2003 Jul 01; 63(13):3667-74. Bading JR, Yoo PB, Fissekis JD, Alauddin MM, D'Argenio DZ, Conti PS. PMID: 12839957.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    54. Physiologically-based pharmacokinetics and molecular pharmacodynamics of 17-(allylamino)-17-demethoxygeldanamycin and its active metabolite in tumor-bearing mice. J Pharmacokinet Pharmacodyn. 2003 Jun; 30(3):185-219. Xu L, Eiseman JL, Egorin MJ, D'Argenio DZ. PMID: 14571691.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimals
    55. Pharmacodynamic model of topotecan-induced time course of neutropenia. Clin Cancer Res. 2001 Aug; 7(8):2301-8. Zamboni WC, D'Argenio DZ, Stewart CF, MacVittie T, Delauter BJ, Farese AM, Potter DM, Kubat NM, Tubergen D, Egorin MJ. PMID: 11489805.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    56. QscR, a modulator of quorum-sensing signal synthesis and virulence in Pseudomonas aeruginosa. Proc Natl Acad Sci U S A. 2001 Feb 27; 98(5):2752-7. Chugani SA, Whiteley M, Lee KM, D'Argenio D, Manoil C, Greenberg EP. PMID: 11226312; PMCID: PMC30211.
      View in: PubMed   Mentions:
    57. Use of drug effect interaction modeling with Monte Carlo simulation to examine the impact of dosing interval on the projected antiviral activity of the combination of abacavir and amprenavir. Antimicrob Agents Chemother. 2000 Jun; 44(6):1655-9. Drusano GL, D'Argenio DZ, Preston SL, Barone C, Symonds W, LaFon S, Rogers M, Prince W, Bye A, Bilello JA. PMID: 10817724.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    58. The triple combination indinavir-zidovudine-lamivudine is highly synergistic. Antimicrob Agents Chemother. 2000 Apr; 44(4):1051-8. Snyder S, D'Argenio DZ, Weislow O, Bilello JA, Drusano GL. PMID: 10722511.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    59. Nucleoside analog 1592U89 and human immunodeficiency virus protease inhibitor 141W94 are synergistic in vitro. Antimicrob Agents Chemother. 1998 Sep; 42(9):2153-9. Drusano GL, D'Argenio DZ, Symonds W, Bilello PA, McDowell J, Sadler B, Bye A, Bilello JA. PMID: 9736527.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    60. Fluid dynamics of a partially collapsible stenosis in a flow model of the coronary circulation. J Biomech Eng. 1996 Nov; 118(4):489-97. Siebes M, Campbell CS, D'Argenio DZ. PMID: 8950652.
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    61. On the correction for radioactive decay in pharmacokinetic modeling. Med Phys. 1995 Oct; 22(10):1619-26. Williams LE, Odom-Maryon TL, Liu A, Chai A, Raubitschek AA, Wong JY, D'Argenio DZ. PMID: 8551986.
      View in: PubMed   Mentions:
    62. Targeting the systemic exposure of teniposide in the population and the individual using a stochastic therapeutic objective. J Pharmacokinet Biopharm. 1993 Apr; 21(2):223-51. D'Argenio DZ, Rodman JH. PMID: 8229682.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    63. Analysis of segmental phosphate absorption in intact rats. A compartmental analysis approach. J Clin Invest. 1993 Mar; 91(3):915-22. Kayne LH, D'Argenio DZ, Meyer JH, Hu MS, Jamgotchian N, Lee DB. PMID: 8450069; PMCID: PMC288044.
      View in: PubMed   Mentions:
    64. Incorporating prior parameter uncertainty in the design of sampling schedules for pharmacokinetic parameter estimation experiments. Math Biosci. 1990 Apr; 99(1):105-18. D'Argenio DZ. PMID: 2134510.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    65. A kinetic model for 99mTc-DMSA in the rat. Eur J Nucl Med. 1990; 16(1):29-34. Maneval DC, D'Argenio DZ, Wolf W. PMID: 2155115.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    66. A minimal model of liver glycogen metabolism; feasibility for predicting flux rates. J Theor Biol. 1988 Dec 07; 135(3):343-58. Kurland IJ, D'Argenio DZ. PMID: 3256724.
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    67. Simulation of linear compartment models with application to nuclear medicine kinetic modeling. Comput Methods Programs Biomed. 1988 Jul-Aug; 27(1):47-54. D'Argenio DZ, Schumitzky A, Wolf W. PMID: 3409681.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    68. Implementation and evaluation of control strategies for individualizing dosage regimens, with application to the aminoglycoside antibiotics. J Pharmacokinet Biopharm. 1986 Oct; 14(5):523-37. Katz D, D'Argenio DZ. PMID: 3806374.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    69. Noninvasive estimation of bound and mobile platinum compounds in the kidney using a radiopharmacokinetic model. J Pharm Sci. 1986 Sep; 75(9):873-7. Brechner RR, D'Argenio DZ, Dahalan R, Wolf W. PMID: 3783454.
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    70. Computer assessment of hemodynamic severity of coronary artery stenosis from angiograms. Comput Methods Programs Biomed. 1985 Nov; 21(2):143-52. Siebes M, D'Argenio DZ, Selzer RH. PMID: 3853488.
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    71. Adaptive control of theophylline therapy: importance of blood sampling times. J Pharmacokinet Biopharm. 1983 Oct; 11(5):547-59. D'Argenio DZ, Khakmahd K. PMID: 6668559.
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    72. Experimental design for estimating integrals by numerical quadrature, with applications to pharmacokinetic studies. Biometrics. 1983 Sep; 39(3):621-8. Katz D, D'Argenio DZ. PMID: 6652198.
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    73. Sampling strategies for noncompartmental estimation of mean residence time. J Pharmacokinet Biopharm. 1983 Aug; 11(4):435-46. D'Argenio DZ, Katz D. PMID: 6668552.
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    74. Optimal inputs for parameter determination of inert gas washout from the lung. Respir Physiol. 1982 Oct; 50(1):111-27. Lewis SM, D'Argenio DZ, Bekey GA, Mittman C. PMID: 6294774.
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    75. Optimal sampling times for pharmacokinetic experiments. J Pharmacokinet Biopharm. 1981 Dec; 9(6):739-56. D'Argenio DZ. PMID: 7341758.
      View in: PubMed   Mentions:
    76. A program package for simulation and parameter estimation in pharmacokinetic systems. Comput Programs Biomed. 1979 Mar; 9(2):115-34. D'Argenio DZ, Schumitzky A. PMID: 761456.
      View in: PubMed   Mentions: 130     Fields:    Translation:Humans
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