Catherine Argyriou, PhD, MS
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| Title(s) | Assistant Professor of Research Ophthalmology |
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| School | Keck School of Medicine of Usc |
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| Address | 4650 Sunset Blvd.
Off Campus
Los Angeles CA 90027
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| vCard | Download vCard |
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Overview
My main research goal is to better understand the mechanisms of genetic diseases and to develop gene-based therapies to treat them, with a focus on peroxisomal disorders. Of particular interest are diseases that can affect multiple systems throughout the body, such as diseases that cause vision loss in conjunction with other organ involvement.
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Completed SC CTSI Mentor Training: Yes
Bibliographic
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media.
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Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication.
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Estimation of PEX1-mediated Zellweger spectrum disorder births and population prevalence by population genetics modeling. Genet Med Open. 2025; 3:103431.
Malone KE, Argyriou C, Zavacky E, Braverman N. PMID: 40519747; PMCID: PMC12166394.
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PubMed Mentions:
1
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Try before you buy: Empirical comparison of base editing approaches. Mol Ther. 2025 Apr 02; 33(4):1310-1311.
Argyriou C, Nagiel A. PMID: 40120588; PMCID: PMC11997487.
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PubMed Mentions: Fields:
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Using multiple modalities to confirm diagnosis in patients with suspected peroxisome biogenesis disorders. Mol Genet Metab. 2025 May; 145(1):109080.
Cheung ACT, Di Pietro E, Argyriou C, Bareke E, D'Souza Y, Puri RD, Muhammed Shabeer P, Ganetzky R, Goldstein A, Vanderver A, Mohan S, Majewski J, Yergeau C, Braverman N. PMID: 40112482; PMCID: PMC12301650.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Spatial characterization of RPE structure and lipids in the PEX1-p.Gly844Asp mouse model for Zellweger spectrum disorder. J Lipid Res. 2025 04; 66(4):100771.
Omri S, Argyriou C, Pryce RS, Di Pietro E, Chaurand P, Braverman N. PMID: 40058592; PMCID: PMC11999432.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
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Zellweger Spectrum Disorder: Ophthalmic Findings from a New Natural History Study Cohort and Scoping Literature Review. Ophthalmology. 2023 12; 130(12):1313-1326.
Yergeau C, Coussa RG, Antaki F, Argyriou C, Koenekoop RK, Braverman NE. PMID: 37541626.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Peroxisomes : novel findings and future directions. Histochem Cell Biol. 2023 May; 159(5):379-387.
Pedrosa AG, Reglinski K, Lismont C, Kors S, Costello J, Rodrigues TA, Marques M, Linka N, Argyriou C, Weinhofer I, Kocherlakota S, Riccio V, Ferreira V, Di Cara F, Ferreira AR, Francisco T, Azevedo JE, Ribeiro D. PMID: 37160800; PMCID: PMC10170047.
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PubMed Mentions:
1 Fields:
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Clinical, neuroradiological, and molecular characterization of patients with atypical Zellweger spectrum disorder caused by PEX16 mutations: a case series. Neurogenetics. 2022 04; 23(2):115-127.
Cheung A, Argyriou C, Yergeau C, D'Souza Y, Riou É, Lévesque S, Raymond G, Daba M, Rtskhiladze I, Tkemaladze T, Adang L, La Piana R, Bernard G, Braverman N. PMID: 35106698.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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AAV-mediated PEX1 gene augmentation improves visual function in the PEX1-Gly844Asp mouse model for mild Zellweger spectrum disorder. Mol Ther Methods Clin Dev. 2021 Dec 10; 23:225-240.
Argyriou C, Polosa A, Song JY, Omri S, Steele B, Cécyre B, McDougald DS, Di Pietro E, Bouchard JF, Bennett J, Hacia JG, Lachapelle P, Braverman NE. PMID: 34703844; PMCID: PMC8516995.
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PubMed Mentions:
11
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The biochemical basis of mitochondrial dysfunction in Zellweger Spectrum Disorder. EMBO Rep. 2021 10 05; 22(10):e51991.
Nuebel E, Morgan JT, Fogarty S, Winter JM, Lettlova S, Berg JA, Chen YC, Kidwell CU, Maschek JA, Clowers KJ, Argyriou C, Chen L, Wittig I, Cox JE, Roh-Johnson M, Braverman N, Bonkowsky J, Gygi SP, Rutter J. PMID: 34351705; PMCID: PMC8490991.
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PubMed Mentions:
27 Fields:
Translation:
HumansCells
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A longitudinal study of retinopathy in the PEX1-Gly844Asp mouse model for mild Zellweger Spectrum Disorder. Exp Eye Res. 2019 09; 186:107713.
Argyriou C, Polosa A, Cecyre B, Hsieh M, Di Pietro E, Cui W, Bouchard JF, Lachapelle P, Braverman N. PMID: 31254513.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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Zellweger spectrum disorder patient-derived fibroblasts with the PEX1-Gly843Asp allele recover peroxisome functions in response to flavonoids. J Cell Biochem. 2019 03; 120(3):3243-3258.
MacLean GE, Argyriou C, Di Pietro E, Sun X, Birjandian S, Saberian P, Hacia JG, Braverman NE. PMID: 30362618.
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PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Peroxisome biogenesis disorders. Transl Sci Rare Dis. 2016 Nov 07; 1(2):111-144.
Argyriou C, D'Agostino MD, Braverman N. PMID: 29152457; PMCID: PMC5678237.
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PubMed Mentions:
43
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An enhanced immune response of Mclk1⁺/⁻ mutant mice is associated with partial protection from fibrosis, cancer and the development of biomarkers of aging. PLoS One. 2012; 7(11):e49606.
Wang D, Wang Y, Argyriou C, Carrière A, Malo D, Hekimi S. PMID: 23166727; PMCID: PMC3498213.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text,
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