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DNA methylation-dependent and -independent binding of CDX2 directs activation of distinct developmental and homeostatic genes. bioRxiv. 2024 Feb 17.
Lorzadeh A, Ye G, Sharma S, Jadhav U. PMID: 38405700; PMCID: PMC10888781.
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Ornithine aminotransferase supports polyamine synthesis in pancreatic cancer. Nature. 2023 04; 616(7956):339-347.
Lee MS, Dennis C, Naqvi I, Dailey L, Lorzadeh A, Ye G, Zaytouni T, Adler A, Hitchcock DS, Lin L, Hoffman MT, Bhuiyan AM, Barth JL, Machacek ME, Mino-Kenudson M, Dougan SK, Jadhav U, Clish CB, Kalaany NY. PMID: 36991126.
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14 Fields:
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HumansAnimals
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Polycomb contraction differentially regulates terminal human hematopoietic differentiation programs. BMC Biol. 2022 05 13; 20(1):104.
Lorzadeh A, Hammond C, Wang F, Knapp DJHF, Wong JC, Zhu JYA, Cao Q, Heravi-Moussavi A, Carles A, Wong M, Sharafian Z, Steif J, Moksa M, Bilenky M, Lavoie PM, Eaves CJ, Hirst M. PMID: 35550087; PMCID: PMC9102747.
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5 Fields:
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HumansCells
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Epigenetic Regulation of Intestinal Stem Cells and Disease: A Balancing Act of DNA and Histone Methylation. Gastroenterology. 2021 06; 160(7):2267-2282.
Lorzadeh A, Romero-Wolf M, Goel A, Jadhav U. PMID: 33775639; PMCID: PMC8169626.
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10 Fields:
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HumansCells
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MYC-induced human acute myeloid leukemia requires a continuing IL-3/GM-CSF costimulus. Blood. 2020 12 10; 136(24):2764-2773.
Bulaeva E, Pellacani D, Nakamichi N, Hammond CA, Beer PA, Lorzadeh A, Moksa M, Carles A, Bilenky M, Lefort S, Shu J, Wilhelm BT, Weng AP, Hirst M, Eaves CJ. PMID: 33301029.
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11 Fields:
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HumansAnimalsCells
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MicroRNA-708 is a novel regulator of the Hoxa9 program in myeloid cells. Leukemia. 2020 05; 34(5):1253-1265.
Schneider E, Pochert N, Ruess C, MacPhee L, Escano L, Miller C, Krowiorz K, Delsing Malmberg E, Heravi-Moussavi A, Lorzadeh A, Ashouri A, Grasedieck S, Sperb N, Kumar Kopparapu P, Iben S, Staffas A, Xiang P, Rösler R, Kanduri M, Larsson E, Fogelstrand L, Döhner H, Döhner K, Wiese S, Hirst M, Keith Humphries R, Palmqvist L, Kuchenbauer F, Rouhi A. PMID: 31768018.
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9 Fields:
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HumansAnimalsCells
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Synthetic modeling reveals HOXB genes are critical for the initiation and maintenance of human leukemia. Nat Commun. 2019 07 02; 10(1):2913.
Kusakabe M, Sun AC, Tyshchenko K, Wong R, Nanda A, Shanna C, Gusscott S, Chavez EA, Lorzadeh A, Zhu A, Hill A, Hung S, Brown S, Babaian A, Wang X, Holt RA, Steidl C, Karsan A, Humphries RK, Eaves CJ, Hirst M, Weng AP. PMID: 31266935; PMCID: PMC6606637.
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4 Fields:
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HumansAnimals
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Autophagy Regulation of Metabolism Is Required for CD8+ T Cell Anti-tumor Immunity. Cell Rep. 2019 04 09; 27(2):502-513.e5.
DeVorkin L, Pavey N, Carleton G, Comber A, Ho C, Lim J, McNamara E, Huang H, Kim P, Zacharias LG, Mizushima N, Saitoh T, Akira S, Beckham W, Lorzadeh A, Moksa M, Cao Q, Murthy A, Hirst M, DeBerardinis RJ, Lum JJ. PMID: 30970253.
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93 Fields:
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HumansAnimalsCells
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Epigenetic Restoration of Fetal-like IGF1 Signaling Inhibits Leukemia Stem Cell Activity. Cell Stem Cell. 2018 11 01; 23(5):714-726.e7.
Giambra V, Gusscott S, Gracias D, Song R, Lam SH, Panelli P, Tyshchenko K, Jenkins CE, Hoofd C, Lorzadeh A, Carles A, Hirst M, Eaves CJ, Weng AP. PMID: 30269902.
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PubMed Mentions:
10 Fields:
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AnimalsCells
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Generation of Native Chromatin Immunoprecipitation Sequencing Libraries for Nucleosome Density Analysis. J Vis Exp. 2017 12 12; (130).
Lorzadeh A, Lopez Gutierrez R, Jackson L, Moksa M, Hirst M. PMID: 29286469; PMCID: PMC5755553.
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PubMed Mentions:
4 Fields:
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Cells
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Death by HDAC Inhibition in Synovial Sarcoma Cells. Mol Cancer Ther. 2017 Dec; 16(12):2656-2667.
Laporte AN, Poulin NM, Barrott JJ, Wang XQ, Lorzadeh A, Vander Werff R, Jones KB, Underhill TM, Nielsen TO. PMID: 28878027.
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18 Fields:
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HumansAnimalsCells
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Atrophin controls developmental signaling pathways via interactions with Trithorax-like. Elife. 2017 03 22; 6.
Yeung K, Boija A, Karlsson E, Holmqvist PH, Tsatskis Y, Nisoli I, Yap D, Lorzadeh A, Moksa M, Hirst M, Aparicio S, Fanto M, Stenberg P, Mannervik M, McNeill H. PMID: 28327288; PMCID: PMC5409829.
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8 Fields:
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AnimalsCells
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Nucleosome Density ChIP-Seq Identifies Distinct Chromatin Modification Signatures Associated with MNase Accessibility. Cell Rep. 2016 11 15; 17(8):2112-2124.
Lorzadeh A, Bilenky M, Hammond C, Knapp DJHF, Li L, Miller PH, Carles A, Heravi-Moussavi A, Gakkhar S, Moksa M, Eaves CJ, Hirst M. PMID: 27851972.
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24 Fields:
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HumansCells
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Thermographic analysis of the radiant heat of chicken and duck eggs in relation to the embryo's oxygen consumption. J Therm Biol. 2015 Feb; 48:77-84.
Mortola JP, Kim J, Lorzadeh A, Leurer C. PMID: 25660634.
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Animals
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Regulatory variation: an emerging vantage point for cancer biology. Wiley Interdiscip Rev Syst Biol Med. 2014 Jan-Feb; 6(1):37-59.
Li L, Lorzadeh A, Hirst M. PMID: 24254976.
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2 Fields:
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Humans