Alexander N. Fedenko, MD

Title(s)Associate Professor of Clinical Pathology
SchoolKeck School of Medicine of Usc
AddressHC4 1450 San Pablo Street
Health Sciences Campus
Los Angeles CA 90089-9092
Phone+1 323 442 8576
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    1. Complete response to talazoparib in patient with pancreatic adenocarcinoma harboring somatic PALB2 mutation: A case report and literature review. Front Oncol. 2022; 12:953908. Kachmazov A, Bolotina L, Kornietskaya A, Kuznetsova O, Ivanov M, Fedenko A. PMID: 36119518; PMCID: PMC9478540.
      View in: PubMed   Mentions:
    2. Remission of a Primary, Recurrent Thoracic Ewing Sarcoma in a 74-year-old woman. Rare Tumors. 2022; 14:20363613221110836. Tungate RM, Lara K, Patel D, Fedenko A, Hu J. PMID: 35813490; PMCID: PMC9260570.
      View in: PubMed   Mentions: 1  
    3. Soft tissue and visceral sarcomas: ESMO-EURACAN-GENTURIS Clinical Practice Guidelines for diagnosis, treatment and follow-up☆. Ann Oncol. 2021 11; 32(11):1348-1365. Gronchi A, Miah AB, Dei Tos AP, Abecassis N, Bajpai J, Bauer S, Biagini R, Bielack S, Blay JY, Bolle S, Bonvalot S, Boukovinas I, Bovee JVMG, Boye K, Brennan B, Brodowicz T, Buonadonna A, De Álava E, Del Muro XG, Dufresne A, Eriksson M, Fagioli F, Fedenko A, Ferraresi V, Ferrari A, Frezza AM, Gasperoni S, Gelderblom H, Gouin F, Grignani G, Haas R, Hassan AB, Hecker-Nolting S, Hindi N, Hohenberger P, Joensuu H, Jones RL, Jungels C, Jutte P, Kager L, Kasper B, Kawai A, Kopeckova K, Krákorová DA, Le Cesne A, Le Grange F, Legius E, Leithner A, Lopez-Pousa A, Martin-Broto J, Merimsky O, Messiou C, Mir O, Montemurro M, Morland B, Morosi C, Palmerini E, Pantaleo MA, Piana R, Piperno-Neumann S, Reichardt P, Rutkowski P, Safwat AA, Sangalli C, Sbaraglia M, Scheipl S, Schöffski P, Sleijfer S, Strauss D, Strauss S, Sundby Hall K, Trama A, Unk M, van de Sande MAJ, van der Graaf WTA, van Houdt WJ, Frebourg T, Casali PG, Stacchiotti S, ESMO Guidelines Committee, EURACAN and GENTURIS. Electronic address: clinicalguidelines@esmo.org. PMID: 34303806.
      View in: PubMed   Mentions: 249     Fields:    Translation:Humans
    4. Systemic therapies in advanced epithelioid haemangioendothelioma: A retrospective international case series from the World Sarcoma Network and a review of literature. Cancer Med. 2021 04; 10(8):2645-2659. Frezza AM, Ravi V, Lo Vullo S, Vincenzi B, Tolomeo F, Chen TW, Teterycz P, Baldi GG, Italiano A, Penel N, Brunello A, Duffaud F, Hindi N, Iwata S, Smrke A, Fedenko A, Gelderblom H, Van Der Graaf W, Vozy A, Connolly E, Grassi M, Benjamin RS, Broto JM, Grignani G, Jones RL, Kawai A, Tysarowski A, Mariani L, Casali PG, Stacchiotti S. PMID: 33713582; PMCID: PMC8026938.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    5. Bizarre parosteal osteochondromatous proliferation: Rare case affecting distal ulna and review of literature. Clin Imaging. 2021 Jan; 69:233-237. Washington E, Menendez L, Fedenko A, Tomasian A. PMID: 32977195.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    6. Effect of Doxorubicin Plus Olaratumab vs Doxorubicin Plus Placebo on Survival in Patients With Advanced Soft Tissue Sarcomas: The ANNOUNCE Randomized Clinical Trial. JAMA. 2020 04 07; 323(13):1266-1276. Tap WD, Wagner AJ, Schöffski P, Martin-Broto J, Krarup-Hansen A, Ganjoo KN, Yen CC, Abdul Razak AR, Spira A, Kawai A, Le Cesne A, Van Tine BA, Naito Y, Park SH, Fedenko A, Pápai Z, Soldatenkova V, Shahir A, Mo G, Wright J, Jones RL, ANNOUNCE Investigators. PMID: 32259228; PMCID: PMC7139275.
      View in: PubMed   Mentions: 111     Fields:    Translation:HumansCTClinical Trials
    7. Systemic treatments in MDM2 positive intimal sarcoma: A multicentre experience with anthracycline, gemcitabine, and pazopanib within the World Sarcoma Network. Cancer. 2020 01 01; 126(1):98-104. Frezza AM, Assi T, Lo Vullo S, Ben-Ami E, Dufresne A, Yonemori K, Noguchi E, Siontis B, Ferraro R, Teterycz P, Duffaud F, Ravi V, Vincenzi B, Gelderblom H, Pantaleo MA, Baldi GG, Desar I, Fedenko A, Maki RG, Jones RL, Benjamin RS, Blay JY, Kawai A, Gounder M, Gronchi A, Le Cesne A, Mir O, Czarnecka AM, Schuetze S, Wagner AJ, Adam J, Barisella M, Sbaraglia M, Hornick JL, Meurgey A, Mariani L, Casali PG, Thornton K, Stacchiotti S. PMID: 31536651; PMCID: PMC9187112.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    8. Bone sarcomas: ESMO-PaedCan-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2018 10 01; 29(Suppl 4):iv79-iv95. Casali PG, Bielack S, Abecassis N, Aro HT, Bauer S, Biagini R, Bonvalot S, Boukovinas I, Bovee JVMG, Brennan B, Brodowicz T, Broto JM, Brugières L, Buonadonna A, De Álava E, Dei Tos AP, Del Muro XG, Dileo P, Dhooge C, Eriksson M, Fagioli F, Fedenko A, Ferraresi V, Ferrari A, Ferrari S, Frezza AM, Gaspar N, Gasperoni S, Gelderblom H, Gil T, Grignani G, Gronchi A, Haas RL, Hassan B, Hecker-Nolting S, Hohenberger P, Issels R, Joensuu H, Jones RL, Judson I, Jutte P, Kaal S, Kager L, Kasper B, Kopeckova K, Krákorová DA, Ladenstein R, Le Cesne A, Lugowska I, Merimsky O, Montemurro M, Morland B, Pantaleo MA, Piana R, Picci P, Piperno-Neumann S, Pousa AL, Reichardt P, Robinson MH, Rutkowski P, Safwat AA, Schöffski P, Sleijfer S, Stacchiotti S, Strauss SJ, Sundby Hall K, Unk M, Van Coevorden F, van der Graaf WTA, Whelan J, Wardelmann E, Zaikova O, Blay JY, ESMO Guidelines Committee, PaedCan and ERN EURACAN. PMID: 30285218.
      View in: PubMed   Mentions: 238     Fields:    Translation:Humans
    9. Soft tissue and visceral sarcomas: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2018 10 01; 29(Suppl 4):iv268-iv269. Casali PG, Abecassis N, Aro HT, Bauer S, Biagini R, Bielack S, Bonvalot S, Boukovinas I, Bovee JVMG, Brodowicz T, Broto JM, Buonadonna A, De Álava E, Dei Tos AP, Del Muro XG, Dileo P, Eriksson M, Fedenko A, Ferraresi V, Ferrari A, Ferrari S, Frezza AM, Gasperoni S, Gelderblom H, Gil T, Grignani G, Gronchi A, Haas RL, Hassan B, Hohenberger P, Issels R, Joensuu H, Jones RL, Judson I, Jutte P, Kaal S, Kasper B, Kopeckova K, Krákorová DA, Le Cesne A, Lugowska I, Merimsky O, Montemurro M, Pantaleo MA, Piana R, Picci P, Piperno-Neumann S, Pousa AL, Reichardt P, Robinson MH, Rutkowski P, Safwat AA, Schöffski P, Sleijfer S, Stacchiotti S, Sundby Hall K, Unk M, Van Coevorden F, van der Graaf WTA, Whelan J, Wardelmann E, Zaikova O, Blay JY, ESMO Guidelines Committee and EURACAN. PMID: 30285214.
      View in: PubMed   Mentions: 84     Fields:    
    10. Soft tissue and visceral sarcomas: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2018 10 01; 29(Suppl 4):iv51-iv67. Casali PG, Abecassis N, Aro HT, Bauer S, Biagini R, Bielack S, Bonvalot S, Boukovinas I, Bovee JVMG, Brodowicz T, Broto JM, Buonadonna A, De Álava E, Dei Tos AP, Del Muro XG, Dileo P, Eriksson M, Fedenko A, Ferraresi V, Ferrari A, Ferrari S, Frezza AM, Gasperoni S, Gelderblom H, Gil T, Grignani G, Gronchi A, Haas RL, Hassan B, Hohenberger P, Issels R, Joensuu H, Jones RL, Judson I, Jutte P, Kaal S, Kasper B, Kopeckova K, Krákorová DA, Le Cesne A, Lugowska I, Merimsky O, Montemurro M, Pantaleo MA, Piana R, Picci P, Piperno-Neumann S, Pousa AL, Reichardt P, Robinson MH, Rutkowski P, Safwat AA, Schöffski P, Sleijfer S, Stacchiotti S, Sundby Hall K, Unk M, Van Coevorden F, van der Graaf WTA, Whelan J, Wardelmann E, Zaikova O, Blay JY, ESMO Guidelines Committee and EURACAN. PMID: 29846498.
      View in: PubMed   Mentions: 284     Fields:    Translation:Humans
    11. Anthracycline, Gemcitabine, and Pazopanib in Epithelioid Sarcoma: A Multi-institutional Case Series. JAMA Oncol. 2018 09 01; 4(9):e180219. Frezza AM, Jones RL, Lo Vullo S, Asano N, Lucibello F, Ben-Ami E, Ratan R, Teterycz P, Boye K, Brahmi M, Palmerini E, Fedenko A, Vincenzi B, Brunello A, Desar IME, Benjamin RS, Blay JY, Broto JM, Casali PG, Gelderblom H, Grignani G, Gronchi A, Hall KS, Mir O, Rutkowski P, Wagner AJ, Anurova O, Collini P, Dei Tos AP, Flucke U, Hornick JL, Lobmaier I, Philippe T, Picci P, Ranchere D, Renne SL, Sbaraglia M, Thway K, Wagrodzki M, Wang WL, Yoshida A, Mariani L, Kawai A, Stacchiotti S. PMID: 29800950; PMCID: PMC6143006.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    12. Human Acellular Dermis as Spacer for Small-Joint Arthroplasty: Analysis of Revascularization in a Rabbit Trapeziectomy Model. Plast Reconstr Surg. 2018 09; 142(3):679-686. Banks K, Squitieri L, Bramos A, Johnson MB, Gardner DJ, Pourmoussa AJ, Jung E, Lee GK, Perrault DP, Fedenko A, Kim GH, Han B, Hong YK, Kulber DA, Wong AK. PMID: 29878993.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    13. Porcine Mesothelium-Wrapped Diced Cartilage Grafts for Nasal Reconstruction. Tissue Eng Part A. 2018 04; 24(7-8):672-681. Bramos A, Perrault DP, Fedenko AN, Kim GH, Bougioukli S, Lieberman JR, Calvert JW, Wong AK. PMID: 28922982.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    14. Activity of Pazopanib and Trabectedin in Advanced Alveolar Soft Part Sarcoma. Oncologist. 2018 01; 23(1):62-70. Stacchiotti S, Mir O, Le Cesne A, Vincenzi B, Fedenko A, Maki RG, Somaiah N, Patel S, Brahmi M, Blay JY, Boye K, Sundby Hall K, Gelderblom H, Hindi N, Martin-Broto J, Kosela H, Rutkowski P, Italiano A, Duffaud F, Kobayashi E, Casali PG, Provenzano S, Kawai A. PMID: 28754721; PMCID: PMC5759809.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    15. Calcifying Fibrous Pseudotumor of the Posterior Mediastinum With Encapsulation of the Thoracic Duct. Ann Thorac Surg. 2016 Jul; 102(1):e39-40. Dissanayake SN, Hagen J, Fedenko A, Lee C. PMID: 27343527.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    16. First-Line Aldoxorubicin vs Doxorubicin in Metastatic or Locally Advanced Unresectable Soft-Tissue Sarcoma: A Phase 2b Randomized Clinical Trial. JAMA Oncol. 2015 Dec; 1(9):1272-80. Chawla SP, Papai Z, Mukhametshina G, Sankhala K, Vasylyev L, Fedenko A, Khamly K, Ganjoo K, Nagarkar R, Wieland S, Levitt DJ. PMID: 26378637.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCTClinical Trials
    17. Immunohistochemical panel to differentiate endometrial stromal sarcoma, uterine leiomyosarcoma and leiomyoma: something old and something new. J Clin Pathol. 2015 Sep; 68(9):710-7. Hwang H, Matsuo K, Duncan K, Pakzamir E, Pham HQ, Correa A, Fedenko A, Mhawech-Fauceglia P. PMID: 25991737; PMCID: PMC7528441.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    18. Prognostic value of necrosis after neoadjuvant therapy for soft tissue sarcoma. J Surg Oncol. 2015 Feb; 111(2):152-7. Vaynrub M, Taheri N, Ahlmann ER, Yao C, Fedenko AN, Allison DC, Chawla SP, Menendez LR. PMID: 25175933.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    19. Bilateral primary xanthoma of the humeri with pathologic fractures: A case report. World J Radiol. 2013 Sep 28; 5(9):345-8. Ali S, Fedenko A, Syed AB, Matcuk G, Patel D, Gottsegen C, White E. PMID: 24198913; PMCID: PMC3817293.
      View in: PubMed   Mentions: 3  
    20. Lipoma arborescens of the biceps tendon sheath. Skeletal Radiol. 2013 Oct; 42(10):1461-4. White EA, Omid R, Matcuk GR, Domzalski JT, Fedenko AN, Gottsegen CJ, Forrester DM, Patel DB. PMID: 23677483.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    21. Clavicular eosinophilic granuloma causing adult shoulder pain. Rare Tumors. 2013 Feb 11; 5(1):e8. Sugi MT, Fedenko AN, Menendez LR, Allison DC. PMID: 23772307; PMCID: PMC3682460.
      View in: PubMed   Mentions: 1  
    22. Combined surgical resection and radiofrequency ablation as treatment for metastatic ocular melanoma. Surg Today. 2013 Apr; 43(4):367-71. Derek E, Matsuoka L, Alexopoulos S, Fedenko A, Genyk Y, Selby R. PMID: 22766897.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    23. Near Complete Necrosis of a Giant Cell Tumor After Treatment with Denosumab: A Case Report. JBJS Case Connect. 2012 Jul-Sep; 2(3):e37. Ahlmann ER, Wang L, Correa AJ, Fedenko AN. PMID: 29252535.
      View in: PubMed   Mentions:    Fields:    
    24. A meta-analysis of osteosarcoma outcomes in the modern medical era. Sarcoma. 2012; 2012:704872. Allison DC, Carney SC, Ahlmann ER, Hendifar A, Chawla S, Fedenko A, Angeles C, Menendez LR. PMID: 22550423; PMCID: PMC3329715.
      View in: PubMed   Mentions: 194  
    25. Human knee synovial fluid cytokines correlated with grade of knee osteoarthritis--a pilot study. Bull NYU Hosp Jt Dis. 2011; 69(2):122-7. Vangsness CT, Burke WS, Narvy SJ, MacPhee RD, Fedenko AN. PMID: 22035391.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    26. A comparison of fine-needle aspiration, core biopsy, and surgical biopsy in the diagnosis of extremity soft tissue masses. Clin Orthop Relat Res. 2010 Nov; 468(11):2992-3002. Kasraeian S, Allison DC, Ahlmann ER, Fedenko AN, Menendez LR. PMID: 20512437; PMCID: PMC2947686.
      View in: PubMed   Mentions: 67     Fields:    Translation:Humans
    27. F-18 FDG PET and PET/CT evaluation of response to chemotherapy in bone and soft tissue sarcomas. Clin Nucl Med. 2008 Jan; 33(1):8-13. Iagaru A, Masamed R, Chawla SP, Menendez LR, Fedenko A, Conti PS. PMID: 18097248.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    28. Cryoablation and resection influences patient survival for soft tissue sarcomas: impact on survivorship and local recurrence. Clin Orthop Relat Res. 2007 Jun; 459:174-81. Ahlmann ER, Falkinstein Y, Fedenko AN, Menendez LR. PMID: 17415009.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    29. Tumor necrosis has no prognostic value in neoadjuvant chemotherapy for soft tissue sarcoma. Clin Orthop Relat Res. 2007 Feb; 455:219-24. Menendez LR, Ahlmann ER, Savage K, Cluck M, Fedenko AN. PMID: 17016226.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    30. Influence of cryosurgery on treatment outcome of low-grade chondrosarcoma. Clin Orthop Relat Res. 2006 Oct; 451:201-7. Ahlmann ER, Menendez LR, Fedenko AN, Learch T. PMID: 16788412.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    31. A rare case of periosteal osteoblastoma located in the frontal cranial bone. Arch Pathol Lab Med. 2005 Jun; 129(6):787-9. Lin YC, Commins DL, Fedenko AN, Pinsky GS. PMID: 15913430.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    32. A prolonged case of Mycobacterium marinum flexor tenosynovitis: radiographic and histological correlation, and review of the literature. Skeletal Radiol. 2003 Sep; 32(9):542-5. Wongworawat MD, Holtom P, Learch TJ, Fedenko A, Stevanovic MV. PMID: 12879295.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    33. Norepinephrine producing renal cell carcinoma. J Urol. 2001 Aug; 166(2):603. Koh CJ, Bochner BH, Stein JP, Fedenko AN, Dequattro V, Skinner DG. PMID: 11458078.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    34. The role of access of joint fluid to bone in periarticular osteolysis. A report of four cases. J Bone Joint Surg Am. 1997 Mar; 79(3):447-52. Schmalzried TP, Akizuki KH, Fedenko AN, Mirra J. PMID: 9070538.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    35. Giant bone island of femur. Case report, literature review, and its distinction from low grade osteosarcoma. Skeletal Radiol. 1995 Oct; 24(7):546-50. Brien EW, Mirra JM, Latanza L, Fedenko A, Luck J. PMID: 8545657.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    36. Case report 827: Miliary osteosarcomatosis. Skeletal Radiol. 1994 Feb; 23(2):143-7. Ippolito V, Mirra JM, Fedenko A, Brien EW, Rosen P, Chap L. PMID: 8191301.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    37. [The characteristics of eicosanoid synthesis in osteogenic sarcoma in children at puberty]. Vopr Onkol. 1992; 38(8):929-35. Kushlinskii NE, Bassalyk LS, Liakina LT, Solov'ev IuN, Pashkov IuV, Amiraslanov AT, Siniukov PA, Valentei LV, Fedenko AN, Abaev VM, et al. PMID: 1300802.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    38. [Polypeptide growth factors and their interrelation with hormones in the blood plasma of patients with primary bone tumors]. Vopr Onkol. 1991; 37(6):676-83. Kushlinskii NE, Bassalyk LS, Kuz'mina ZV, Solov'ev IuN, Eremina LA, Amiraslanov AT, Shatskaia VA, Demina DG, Fedenko AN, Siniukov PA, et al. PMID: 1843144.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    39. [Clear-cell chondrosarcoma of bone]. Arkh Patol. 1990; 52(5):55-8. Povísil C, Siniukov PA, Fedenko AN. PMID: 2396920.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    40. [The results of using high-dose methotrexate in treating osteogenic sarcoma]. Vopr Onkol. 1990; 36(6):667-71. Perevodchikova NI, Eremina LA, Manziuk LV, Siniukov PA, Fedenko AN, Singin AS, Moldovanova LK. PMID: 2378085.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    41. [The relationship between the prostaglandin E level in the tumor and the times of the metastasis of primary osteogenic sarcoma]. Vopr Onkol. 1989; 35(11):1301-5. Bassalyk LS, Kushlinskii NE, Solov'ev IuN, Siniukov PA, Fedenko AN. PMID: 2609517.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    42. [Malignant fibrous histiocytoma of the soft tissues]. Arkh Patol. 1985; 47(9):20-8. Fedenko AN, Blinov VM, Solov'ev IuN. PMID: 3000323.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
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