Alessandro Altoe, PhD

Title(s)Instructor Of Research Otolaryngology-Head and Neck Surgery
SchoolKeck School of Medicine of Usc
Address1537 Norfolk St.
Health Sciences Campus
Los Angeles CA 90033
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    Dr. Altoè is an Electrical Engineer and Acoustician. Since 2018 he has been a member of the Auditory Physics Group, where he studies cochlear mechanics. His research has a keen focus on identifying the signal processing strategies within the cochlea that enable healthy ears outperform man-made technology.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Intracochlear overdrive: Characterizing nonlinear wave amplification in the mouse apex. J Acoust Soc Am. 2023 11 01; 154(5):3414-3428. Altoè A, Charaziak KK. PMID: 38015028; PMCID: PMC10686682.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    2. Otoacoustic emissions reveal the micromechanical role of organ-of-Corti cytoarchitecture in cochlear amplification. Proc Natl Acad Sci U S A. 2023 10 10; 120(41):e2305921120. Shera CA, Altoè A. PMID: 37796989; PMCID: PMC10576130.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    3. Estimating cochlear impulse responses using frequency sweeps. J Acoust Soc Am. 2023 04 01; 153(4):2251. Charaziak KK, Altoè A. PMID: 37092917; PMCID: PMC10104686.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    4. The Long Outer-Hair-Cell RC Time Constant: A Feature, Not a Bug, of the Mammalian Cochlea. J Assoc Res Otolaryngol. 2023 04; 24(2):129-145. Altoè A, Shera CA. PMID: 36725778; PMCID: PMC10121995.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    5. The Remarkable Outer Hair Cell: Proceedings of a Symposium in Honour of W. E. Brownell. J Assoc Res Otolaryngol. 2023 04; 24(2):117-127. Ashmore JF, Oghalai JS, Dewey JB, Olson ES, Strimbu CE, Wang Y, Shera CA, Altoè A, Abdala C, Elgoyhen AB, Eatock RA, Raphael RM. PMID: 36648734; PMCID: PMC10121982.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    6. Crucial 3-D viscous hydrodynamic contributions to the theoretical modeling of the cochlear response. J Acoust Soc Am. 2023 01; 153(1):77. Sisto R, Belardinelli D, Altoè A, Shera CA, Moleti A. PMID: 36732225; PMCID: PMC10167633.
      View in: PubMed   Mentions: 2     Fields:    
    7. Overturning the mechanisms of cochlear amplification via area deformations of the organ of Corti. J Acoust Soc Am. 2022 10; 152(4):2227. Altoè A, Dewey JB, Charaziak KK, Oghalai JS, Shera CA. PMID: 36319240; PMCID: PMC9578757.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    8. Cochlear outer hair cell electromotility enhances organ of Corti motion on a cycle-by-cycle basis at high frequencies in vivo. Proc Natl Acad Sci U S A. 2021 10 26; 118(43). Dewey JB, Altoè A, Shera CA, Applegate BE, Oghalai JS. PMID: 34686590; PMCID: PMC8639341.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    9. The Elusive Cochlear Filter: Wave Origin of Cochlear Cross-Frequency Masking. J Assoc Res Otolaryngol. 2021 12; 22(6):623-640. Altoè A, Charaziak KK, Dewey JB, Moleti A, Sisto R, Oghalai JS, Shera CA. PMID: 34677710; PMCID: PMC8599594.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    10. The cochlear ear horn: geometric origin of tonotopic variations in auditory signal processing. Sci Rep. 2020 11 25; 10(1):20528. Altoè A, Shera CA. PMID: 33239701; PMCID: PMC7689495.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    11. Optimized Tuning of Auditory Inner Hair Cells to Encode Complex Sound through Synergistic Activity of Six Independent K+ Current Entities. Cell Rep. 2020 07 07; 32(1):107869. Dierich M, Altoè A, Koppelmann J, Evers S, Renigunta V, Schäfer MK, Naumann R, Verhulst S, Oliver D, Leitner MG. PMID: 32640234.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    12. Asymmetry and Microstructure of Temporal-Suppression Patterns in Basilar-Membrane Responses to Clicks: Relation to Tonal Suppression and Traveling-Wave Dispersion. J Assoc Res Otolaryngol. 2020 04; 21(2):151-170. Charaziak KK, Dong W, Altoè A, Shera CA. PMID: 32166602; PMCID: PMC7270478.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    13. Nonlinear cochlear mechanics without direct vibration-amplification feedback. Phys Rev Res. 2020 Feb-Apr; 2(1). Altoè A, Shera CA. PMID: 33403361; PMCID: PMC7781069.
      View in: PubMed   Mentions: 13  
    14. Constraints imposed by zero-crossing invariance on cochlear models with two mechanical degrees of freedom. J Acoust Soc Am. 2019 09; 146(3):1685. Sisto R, Shera CA, Altoè A, Moleti A. PMID: 31590512; PMCID: PMC6756920.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    15. The effects of the activation of the inner-hair-cell basolateral K+ channels on auditory nerve responses. Hear Res. 2018 07; 364:68-80. Altoè A, Pulkki V, Verhulst S. PMID: 29678326.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    16. Computational modeling of the human auditory periphery: Auditory-nerve responses, evoked potentials and hearing loss. Hear Res. 2018 03; 360:55-75. Verhulst S, Altoè A, Vasilkov V. PMID: 29472062.
      View in: PubMed   Mentions: 48     Fields:    Translation:Humans
    17. Dynamics of cochlear nonlinearity: Automatic gain control or instantaneous damping? J Acoust Soc Am. 2017 12; 142(6):3510. Altoè A, Charaziak KK, Shera CA. PMID: 29289066; PMCID: PMC5726976.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    18. Model-based estimation of the frequency tuning of the inner-hair-cell stereocilia from neural tuning curves. J Acoust Soc Am. 2017 06; 141(6):4438. Altoè A, Pulkki V, Verhulst S. PMID: 28679269.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    19. Decoupling the level dependence of the basilar membrane gain and phase in nonlinear cochlea models. J Acoust Soc Am. 2015 Aug; 138(2):EL155-60. Sisto R, Moleti A, Altoè A. PMID: 26328742.
      View in: PubMed   Mentions: 8     Fields:    
    20. Integrated processing of spatial cues in human auditory cortex. Hear Res. 2015 Sep; 327:143-52. Salminen NH, Takanen M, Santala O, Lamminsalo J, Altoè A, Pulkki V. PMID: 26074304.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    21. Human cortical sensitivity to interaural time difference in high-frequency sounds. Hear Res. 2015 May; 323:99-106. Salminen NH, Altoè A, Takanen M, Santala O, Pulkki V. PMID: 25668126.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    22. Transmission line cochlear models: improved accuracy and efficiency. J Acoust Soc Am. 2014 Oct; 136(4):EL302-8. Altoè A, Pulkki V, Verhulst S. PMID: 25324114.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
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    NIH Funding Acknowledgment: Important - All publications resulting from the utilization of SC CTSI resources are required to credit the SC CTSI grant by including the NIH funding acknowledgment and must comply with the NIH Public Access Policy.

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