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    Jeanmarie Bouteiller, PhD

    TitleResearch Assistant Professor
    SchoolViterbi School of Engineering, BME
    DepartmentBiomedical Engineering
    AddressHNB 412
    University Park Campus
    Los Angeles California 90089-1111
    Phone+1 213 821 4278

       Overview 
       Overview
      Jean-Marie Bouteiller joined the University of Southern California with a Masters in Electrical Engineering and Computer Science (from University of Montpellier, FRANCE) to start a PhD in Computational Neuroscience with Prof. Michel Baudry. With this dual competency in Neuroscience and Engineering, he joined in 2002 the laboratory of Prof. Theodore W. Berger to start the development of a unique computational synaptic modeling platform that would take into account the multitude of mechanisms that comprise presynaptic terminal, cleft and postsynaptic spine. This platform has substantially grown throughout the years to include a large number of mechanisms and modulatory pathways as well as astrocytic modulation, while extending its hierarchical structure to span multiple biological scales, from biomolecular mechanisms to synapse, neuron and neuronal network.


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       Bibliographic 
       Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Bingham CS, Loizos K. A large-scale detailed neuronal model of electrical stimulation of the dentate gyrus and perforant path as a platform for electrode design and optimization. Conf Proc IEEE Eng Med Biol Soc. 2016 Aug; 2016:2794-2797..
        View in: PubMed
      2. Hu EY, Bouteiller JC. Development of a detailed model of calcium dynamics at the postsynaptic spine of an excitatory synapse. Conf Proc IEEE Eng Med Biol Soc. 2016 Aug; 2016:6102-6105..
        View in: PubMed
      3. Keller A, Ambert N, Legendre A, Bedez M, Bouteiller JM, Bischoff S, Baudry M, Moussaoui S. Impact of synaptic localization and subunit composition of ionotropic glutamate receptors on synaptic function: modeling and simulation studies. IEEE/ACM Trans Comput Biol Bioinform. 2016 May 03..
        View in: PubMed
      4. Keller A, Ambert N, Legendre A, Bedez M, Bouteiller JM, Bischoff S, Baudry M, Moussaoui S. Impact of synaptic localization and subunit composition of ionotropic glutamate receptors on synaptic function: modeling and simulation studies. IEEE/ACM Trans Comput Biol Bioinform. 2016 May 03..
        View in: PubMed
      5. Greget R, Dadak S, Barbier L, Lauga F, Linossier-Pierre S, Pernot F, Legendre A, Ambert N, Bouteiller JM, Dorandeu F, Bischoff S, Baudry M, Fagni L, Moussaoui S. Modeling and simulation of organophosphate-induced neurotoxicity: Prediction and validation by experimental studies. Neurotoxicology. 2016 May; 54:140-52..
        View in: PubMed
      6. Allam SL, Bouteiller JM, Hu EY, Ambert N, Greget R, Bischoff S, Baudry M, Berger TW. Synaptic Efficacy as a Function of Ionotropic Receptor Distribution: A Computational Study. PLoS One. 2015; 10(10):e0140333..
        View in: PubMed
      7. Bedez M, Belhachmi Z, Haeberlé O, Greget R, Moussaoui S, Bouteiller JM, Bischoff S. A fully parallel in time and space algorithm for simulating the electrical activity of a neural tissue. J Neurosci Methods. 2016 Jan 15; 257:17-25..
        View in: PubMed
      8. Hu EY, Bouteiller JM, Song D, Baudry M, Berger TW. Volterra representation enables modeling of complex synaptic nonlinear dynamics in large-scale simulations. Front Comput Neurosci. 2015; 9:112..
        View in: PubMed
      9. Hu EY, Bouteiller JM. The volterra functional series is a viable alternative to kinetic models for synaptic modeling -calibration and benchmarking. Conf Proc IEEE Eng Med Biol Soc. 2015 Aug; 2015:3291-4..
        View in: PubMed
      10. Somogyi ET, Bouteiller JM, Glazier JA, König M, Medley JK, Swat MH, Sauro HM. libRoadRunner: a high performance SBML simulation and analysis library. Bioinformatics. 2015 Oct 15; 31(20):3315-21..
        View in: PubMed
      11. Hu EY, Bouteiller JM, Huang M. A comparison between direct and indirect measurements of neurotransmitter vesicle release dynamics: A computational study. Conf Proc IEEE Eng Med Biol Soc. 2014 Aug; 2014:1155-8..
        View in: PubMed
      12. Ghaderi VS, Song D, Bouteiller JM, Choma J, Berger TW. A programmable analog subthreshold biomimetic model for bi-directional communication with the brain. Conf Proc IEEE Eng Med Biol Soc. 2013; 2013:787-90..
        View in: PubMed
      13. Bouteiller JM, Allam SL, Ambert N, Greget R, Hu E, Bischoff S, Baudry M, Berger TW. Influence of ionotropic receptors localization on glutamatergic synaptic response to paired-pulse stimulation protocol. Conf Proc IEEE Eng Med Biol Soc. 2013; 2013:1037-40..
        View in: PubMed
      14. Bouteiller JM, Hu E, Allam SL, Ghaderi V, Song D, Berger TW. Insights on synaptic paired-pulse response using parametric and non-parametric models. Conf Proc IEEE Eng Med Biol Soc. 2013; 2013:1041-4..
        View in: PubMed
      15. Allam SL, Ghaderi VS, Bouteiller JM, Legendre A, Ambert N, Greget R, Bischoff S, Baudry M, Berger TW. A computational model to investigate astrocytic glutamate uptake influence on synaptic transmission and neuronal spiking. Front Comput Neurosci. 2012; 6:70..
        View in: PubMed
      16. Allam SL, Bouteiller JM, Hu E, Greget R, Ambert N, Bischoff S, Baudry M, Berger TW. Influence of ionotropic receptor location on their dynamics at glutamatergic synapses. Conf Proc IEEE Eng Med Biol Soc. 2012; 2012:1374-7..
        View in: PubMed
      17. Bouteiller JM, Legendre A, Allam SL, Ambert N, Hu EY, Greget R, Keller AF, Pernot F, Bischoff S, Baudry M, Berger TW. Modeling of the nervous system: from modulation of glutamatergic and gabaergic molecular dynamics to neuron spiking activity. Conf Proc IEEE Eng Med Biol Soc. 2012; 2012:6612-5..
        View in: PubMed
      18. Greget R, Pernot F, Bouteiller JM, Ghaderi V, Allam S, Keller AF, Ambert N, Legendre A, Sarmis M, Haeberle O, Faupel M, Bischoff S, Berger TW, Baudry M. Simulation of postsynaptic glutamate receptors reveals critical features of glutamatergic transmission. PLoS One. 2011; 6(12):e28380..
        View in: PubMed
      19. Bouteiller JM, Allam SL, Hu EY, Greget R, Ambert N, Keller AF, Pernot F, Bischoff S, Baudry M, Berger TW. Modeling of the nervous system: From molecular dynamics and synaptic modulation to neuron spiking activity. Conf Proc IEEE Eng Med Biol Soc. 2011 Aug; 2011:445-8..
        View in: PubMed
      20. Ghaderi VS, Allam SL, Ambert N, Bouteiller JM, Choma J, Berger TW. Modeling neuron-glia interactions: From parametric model to neuromorphic hardware. Conf Proc IEEE Eng Med Biol Soc. 2011 Aug; 2011:3581-4..
        View in: PubMed
      21. Bouteiller JM, Allam SL, Hu EY, Greget R, Ambert N, Keller AF, Bischoff S, Baudry M, Berger TW. Integrated multiscale modeling of the nervous system: predicting changes in hippocampal network activity by a positive AMPA receptor modulator. IEEE Trans Biomed Eng. 2011 Oct; 58(10):3008-11..
        View in: PubMed
      22. Bouteiller JM, Allam SL, Greget R, Ambert N, Hu EY, Bischoff S, Baudry M, Berger TW. Paired-pulse stimulation at glutamatergic synapses - pre- and postsynaptic components. Conf Proc IEEE Eng Med Biol Soc. 2010; 2010:787-90..
        View in: PubMed
      23. Ambert N, Greget R, Haeberlé O, Bischoff S, Berger TW, Bouteiller JM, Baudry M. Computational studies of NMDA receptors: differential effects of neuronal activity on efficacy of competitive and non-competitive antagonists. Open Access Bioinformatics. 2010; 2:113-125..
        View in: PubMed
      24. Bouteiller JM, Baudry M, Allam SL, Greget RJ, Bischoff S, Berger TW. Modeling glutamatergic synapses: insights into mechanisms regulating synaptic efficacy. J Integr Neurosci. 2008 Jun; 7(2):185-97..
        View in: PubMed
      25. Bouteiller JM, Qiu Y, Ziane MB, Baudry M, Berger TW. EONS: an online synaptic modeling platform. Conf Proc IEEE Eng Med Biol Soc. 2006; 1:4155-8..
        View in: PubMed
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