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Uri Elkayam, MD

Title(s)Clinical Professor of Medicine (Part-Time)
Phone+1 323 226 7541
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    Collapse Biography 
    Collapse Awards and Honors
    8th World Congress on Heart Failure 2002Melvin L. Marcus Memorial Award for Distinguished Contribution as a Gifted Teacher
    Department of Maternal- Fetal Medicine, USC Women's & Children's Hospital 2002Award for Education of Residents and Fellows
    International Academy of Cardiology2007Distinguished Fellowship Award- Cardiology

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    Collapse Overview
    Uri Elkayam, MD is a Professor of Medicine and a Professor of Obstetrics and Gynecology at the University of Southern California. He is a nationally and internationally known expert in heart failure and heart disease in pregnancy. Dr Elkayam is a past member of the executive council of the Heart Failure Society of America and the chairman of its corporate affairs committee. He is a present or past editorial board member of the Journal of the American College of Cardiology , American Journal of Cardiology, Journal of Cardiac Failure, Heart Failure, Heart Failure Reviews, Journal of Preventive Cardiology and Cardiology in Review.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Elkayam U, Schäfer A, Chieffo A, Lansky A, Hall S, Arany Z, Grines C. Use of Impella heart pump for management of women with peripartum cardiogenic shock. Clin Cardiol. 2019 Oct; 42(10):974-981. PMID: 31436333.
      View in: PubMed
    2. Koczo A, Marino A, Jeyabalan A, Elkayam U, Cooper LT, Fett J, Briller J, Hsich E, Blauwet L, McTiernan C, Morel PA, Hanley-Yanez K, McNamara DM. Breastfeeding, Cellular Immune Activation, and Myocardial Recovery in Peripartum Cardiomyopathy. JACC Basic Transl Sci. 2019 Jun; 4(3):291-300. PMID: 31312753.
      View in: PubMed
    3. Honigberg MC, Elkayam U, Rajagopalan N, Modi K, Briller JE, Drazner MH, Wells GL, McNamara DM, Givertz MM. Electrocardiographic findings in peripartum cardiomyopathy. Clin Cardiol. 2019 May; 42(5):524-529. PMID: 30843220.
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    4. Damp JA, Arany Z, Fett JD, Blauwet L, Elkayam U. Imbalanced Angiogenesis in Peripartum Cardiomyopathy (PPCM). Circ J. 2018 09 25; 82(10):2689. PMID: 30122728.
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    5. Peterson EJ, Ng TMH, Patel KA, Lou M, Elkayam U. Association of admission vs. nadir serum albumin concentration with short-term treatment outcomes in patients with acute heart failure. J Int Med Res. 2018 Sep; 46(9):3665-3674. PMID: 29865919.
      View in: PubMed
    6. Elkayam U. How to Predict Pregnancy Risk in an Individual Woman With Heart Disease. J Am Coll Cardiol. 2018 05 29; 71(21):2431-2433. PMID: 29793632.
      View in: PubMed
    7. Goland S, Elkayam U. Peripartum cardiomyopathy: approach to management. Curr Opin Cardiol. 2018 05; 33(3):347-353. PMID: 29601327.
      View in: PubMed
    8. Elkayam U, Havakuk O. Pregnancy-Associated Coronary Artery Dissection: A Therapeutic Dilemma. J Am Coll Cardiol. 2018 01 30; 71(4):469-470. PMID: 29389369.
      View in: PubMed
    9. Goland S, Elkayam U. Pregnancy and Marfan syndrome. Ann Cardiothorac Surg. 2017 Nov; 6(6):642-653. PMID: 29270376.
      View in: PubMed
    10. Elkayam U. Can I get pregnant again? Eur J Heart Fail. 2017 12; 19(12):1729-1731. PMID: 29027340.
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    11. Elkayam U. Peripartum cardiomyopathy for the clinician: the known and the unknown. Eur J Heart Fail. 2017 09; 19(9):1142-1144. PMID: 28653358.
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    12. Elkayam U. Anticoagulation Therapy for Pregnant Women With Mechanical Prosthetic Heart Valves: How to Improve Safety? J Am Coll Cardiol. 2017 06 06; 69(22):2692-2695. PMID: 28571632.
      View in: PubMed
    13. Schelbert EB, Elkayam U, Cooper LT, Givertz MM, Alexis JD, Briller J, Felker GM, Chaparro S, Kealey A, Pisarcik J, Fett JD, McNamara DM. Myocardial Damage Detected by Late Gadolinium Enhancement Cardiac Magnetic Resonance Is Uncommon in Peripartum Cardiomyopathy. J Am Heart Assoc. 2017 Apr 03; 6(4). PMID: 28373243.
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    14. Havakuk O, King KS, Grazette L, Yoon AJ, Fong M, Bregman N, Elkayam U, Kloner RA. Heart Failure-Induced Brain Injury. J Am Coll Cardiol. 2017 Mar 28; 69(12):1609-1616. PMID: 28335844.
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    15. Havakuk O, Goland S, Mehra A, Elkayam U. Pregnancy and the Risk of Spontaneous Coronary Artery Dissection: An Analysis of 120 Contemporary Cases. Circ Cardiovasc Interv. 2017 Mar; 10(3). PMID: 28302642.
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    16. Havakuk O, Elkayam U. Angiotensin Receptor-Neprilysin Inhibition. J Cardiovasc Pharmacol Ther. 2017 07; 22(4):356-364. PMID: 28587583.
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    17. Elkayam U. Reply: CT Rather Than Invasive Angiography for Pregnant Patients With NSTEMI? More Delay and More Radiation. J Am Coll Cardiol. 2016 12 20; 68(24):2717-2718. PMID: 27978960.
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    18. Liu S, Elkayam U, Naqvi TZ. Echocardiography in Pregnancy: Part 1. Curr Cardiol Rep. 2016 09; 18(9):92. PMID: 27491768.
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    19. Narayanan M, Elkayam U, Naqvi TZ. Echocardiography in Pregnancy: Part 2. Curr Cardiol Rep. 2016 09; 18(9):90. PMID: 27457084.
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    20. Arany Z, Elkayam U. Response by Arany and Elkayam to Letter Regarding Article, "Peripartum Cardiomyopathy". Circulation. 2016 Aug 16; 134(7):e83-4. PMID: 27528651.
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    21. Elkayam U, Goland S, Pieper PG, Silverside CK. High-Risk Cardiac Disease in Pregnancy: Part I. J Am Coll Cardiol. 2016 07 26; 68(4):396-410. PMID: 27443437.
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    22. Elkayam U, Goland S, Pieper PG, Silversides CK. High-Risk Cardiac Disease in Pregnancy: Part II. J Am Coll Cardiol. 2016 Aug 02; 68(5):502-516. PMID: 27443948.
      View in: PubMed
    23. Ng TM, Goland S, Elkayam U. Relaxin for the Treatment of Acute Decompensated Heart Failure: Pharmacology, Mechanisms of Action, and Clinical Evidence. Cardiol Rev. 2016 Jul-Aug; 24(4):194-204. PMID: 26331289.
      View in: PubMed
    24. Elkayam U, Habakuk O. The Search for a Crystal Ball to Predict Early Recovery From Peripartum Cardiomyopathy? JACC Heart Fail. 2016 05; 4(5):389-91. PMID: 27126284.
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    25. Arany Z, Elkayam U. Peripartum Cardiomyopathy. Circulation. 2016 Apr 05; 133(14):1397-409. PMID: 27045128.
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    26. Sheppard R, Hsich E, Damp J, Elkayam U, Kealey A, Ramani G, Zucker M, Alexis JD, Horne BD, Hanley-Yanez K, Pisarcik J, Halder I, Fett JD, McNamara DM. GNB3 C825T Polymorphism and Myocardial Recovery in Peripartum Cardiomyopathy: Results of the Multicenter Investigations of Pregnancy-Associated Cardiomyopathy Study. Circ Heart Fail. 2016 Mar; 9(3):e002683. PMID: 26915373.
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    27. McNamara DM, Elkayam U, Cooper L, Fett JD. Reply: Comparison of the American PPCM Registry Data With International Registries. J Am Coll Cardiol. 2016 Feb 16; 67(6):734-735. PMID: 26868699.
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    28. Ware JS, Li J, Mazaika E, Yasso CM, DeSouza T, Cappola TP, Tsai EJ, Hilfiker-Kleiner D, Kamiya CA, Mazzarotto F, Cook SA, Halder I, Prasad SK, Pisarcik J, Hanley-Yanez K, Alharethi R, Damp J, Hsich E, Elkayam U, Sheppard R, Kealey A, Alexis J, Ramani G, Safirstein J, Boehmer J, Pauly DF, Wittstein IS, Thohan V, Zucker MJ, Liu P, Gorcsan J, McNamara DM, Seidman CE, Seidman JG, Arany Z. Shared Genetic Predisposition in Peripartum and Dilated Cardiomyopathies. N Engl J Med. 2016 Jan 21; 374(3):233-41. PMID: 26735901.
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    29. McNamara DM, Elkayam U, Alharethi R, Damp J, Hsich E, Ewald G, Modi K, Alexis JD, Ramani GV, Semigran MJ, Haythe J, Markham DW, Marek J, Gorcsan J, Wu WC, Lin Y, Halder I, Pisarcik J, Cooper LT, Fett JD. Clinical Outcomes for Peripartum Cardiomyopathy in North America: Results of the IPAC Study (Investigations of Pregnancy-Associated Cardiomyopathy). J Am Coll Cardiol. 2015 Aug 25; 66(8):905-14. PMID: 26293760.
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    30. Goland S, Elkayam U. "Of mice and (wo)men": The need to confirm results of animal experimentations with solid clinical data. Trends Cardiovasc Med. 2015 Aug; 25(6):505-7. PMID: 25908533.
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    31. Elkayam U. Risk of subsequent pregnancy in women with a history of peripartum cardiomyopathy. J Am Coll Cardiol. 2014 Oct 14; 64(15):1629-36. PMID: 25301468.
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    32. Ruys TP, Maggioni A, Johnson MR, Sliwa K, Tavazzi L, Schwerzmann M, Nihoyannopoulos P, Kozelj M, Marelli A, Elkayam U, Hall R, Roos-Hesselink JW. Cardiac medication during pregnancy, data from the ROPAC. Int J Cardiol. 2014 Nov 15; 177(1):124-8. PMID: 25499355.
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    33. Kazory A, Elkayam U. Cardiorenal interactions in acute decompensated heart failure: contemporary concepts facing emerging controversies. J Card Fail. 2014 Dec; 20(12):1004-11. PMID: 25230240.
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    34. Ng TM, Cao DX, Patel KA, Wong YM, Prasad M, Lou M, Elkayam U. Association of hyponatremia to diuretic response and incidence of increased serum creatinine levels in hospitalized patients with acute decompensated heart failure. Cardiology. 2014; 128(4):333-42. PMID: 24942293.
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    35. Elkayam U, Jalnapurkar S, Barakkat MN, Khatri N, Kealey AJ, Mehra A, Roth A. Pregnancy-associated acute myocardial infarction: a review of contemporary experience in 150 cases between 2006 and 2011. Circulation. 2014 Apr 22; 129(16):1695-702. PMID: 24753549.
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    36. Ferdinand KC, Elkayam U, Mancini D, Ofili E, Piña I, Anand I, Feldman AM, McNamara D, Leggett C. Use of isosorbide dinitrate and hydralazine in African-Americans with heart failure 9 years after the African-American Heart Failure Trial. Am J Cardiol. 2014 Jul 01; 114(1):151-9. PMID: 24846808.
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    37. Goland S, Schwartzenberg S, Fan J, Kozak N, Khatri N, Elkayam U. Monitoring of anti-Xa in pregnant patients with mechanical prosthetic valves receiving low-molecular-weight heparin: peak or trough levels? J Cardiovasc Pharmacol Ther. 2014 Sep; 19(5):451-6. PMID: 24607762.
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    38. Sliwa K, Hilfiker-Kleiner D, Mebazaa A, Petrie MC, Maggioni AP, Regitz-Zagrosek V, Schaufelberger M, Tavazzi L, van Veldhuisen DJ, Roos-Hesslink JW, Shah AJ, Seferovic PM, Elkayam U, van Spaendonck-Zwarts K, Bachelier-Walenta K, Mouquet F, Kraigher-Krainer E, Hall R, Ponikowski P, McMurray JJ, Pieske B. EURObservational Research Programme: a worldwide registry on peripartum cardiomyopathy (PPCM) in conjunction with the Heart Failure Association of the European Society of Cardiology Working Group on PPCM. Eur J Heart Fail. 2014 May; 16(5):583-91. PMID: 24591060.
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    39. Gleicher N, Elkayam U. Some more on preventing congenital heart block. Autoimmun Rev. 2014 Jan; 13(1):73-4. PMID: 24035837.
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    40. Packer M, Carson P, Elkayam U, Konstam MA, Moe G, O'Connor C, Rouleau JL, Schocken D, Anderson SA, DeMets DL. Effect of amlodipine on the survival of patients with severe chronic heart failure due to a nonischemic cardiomyopathy: results of the PRAISE-2 study (prospective randomized amlodipine survival evaluation 2). JACC Heart Fail. 2013 Aug; 1(4):308-314. PMID: 24621933.
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    41. Schwartzenberg S, Perlman S, Levy R, Elkayam U, Goland S. Mechanical heart valve thrombosis in pregnancy. J Heart Valve Dis. 2013 Jul; 22(4):603-6. PMID: 24224428.
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    42. Gleicher N, Elkayam U. Preventing congenital neonatal heart block in offspring of mothers with anti-SSA/Ro and SSB/La antibodies: a review of published literature and registered clinical trials. Autoimmun Rev. 2013 Sep; 12(11):1039-45. PMID: 23684701.
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    43. Goland S, Modi K, Hatamizadeh P, Elkayam U. Differences in clinical profile of African-American women with peripartum cardiomyopathy in the United States. J Card Fail. 2013 Apr; 19(4):214-8. PMID: 23582086.
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    44. Ng TM, Konopka E, Hyderi AF, Hshieh S, Tsuji Y, Kim BJ, Han SY, Phan DH, Jeng AI, Lou M, Elkayam U. Comparison of bumetanide- and metolazone-based diuretic regimens to furosemide in acute heart failure. J Cardiovasc Pharmacol Ther. 2013 Jul; 18(4):345-53. PMID: 23538300.
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    45. Colletti PM, Lee KH, Elkayam U. Cardiovascular imaging of the pregnant patient. AJR Am J Roentgenol. 2013 Mar; 200(3):515-21. PMID: 23436839.
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    46. Goland S, Elkayam U. Anticoagulation in pregnancy. Cardiol Clin. 2012 Aug; 30(3):395-405. PMID: 22813365.
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    47. Elkayam U, Jalnapurkar S, Barakat M. Peripartum cardiomyopathy. Cardiol Clin. 2012 Aug; 30(3):435-40. PMID: 22813368.
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    48. Ouzounian JG, Elkayam U. Physiologic changes during normal pregnancy and delivery. Cardiol Clin. 2012 Aug; 30(3):317-29. PMID: 22813360.
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    49. Sahni G, Elkayam U. Cardiovascular disease in pregnancy. Preface. Cardiol Clin. 2012 Aug; 30(3):xi-xii. PMID: 22813373.
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    50. Frishman WH, Elkayam U, Aronow WS. Cardiovascular drugs in pregnancy. Cardiol Clin. 2012 Aug; 30(3):463-91. PMID: 22813371.
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    51. Ng TM, Hshieh S, Chan CY, Elkayam U. Clinical experience with low-dose continuous infusion of furosemide in acute heart failure: assessment of efficacy and safety. J Cardiovasc Pharmacol Ther. 2012 Dec; 17(4):373-81. PMID: 22610091.
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    52. Naqvi TZ, Elkayam U. Serial echocardiographic assessment of the human heart in normal pregnancy. Circ Cardiovasc Imaging. 2012 May 01; 5(3):283-5. PMID: 22592007.
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    53. Elkayam U, Goland S. The search for a safe and effective anticoagulation regimen in pregnant women with mechanical prosthetic heart valves. J Am Coll Cardiol. 2012 Mar 20; 59(12):1116-8. PMID: 22421306.
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    54. Elkayam U. Clinical characteristics of peripartum cardiomyopathy in the United States: diagnosis, prognosis, and management. J Am Coll Cardiol. 2011 Aug 09; 58(7):659-70. PMID: 21816300.
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    55. Ng TM, Ackerbauer KA, Hyderi AF, Hshieh S, Elkayam U. Comparative effects of nesiritide and nitroglycerin on renal function, and incidence of renal injury by traditional and RIFLE criteria in acute heart failure. J Cardiovasc Pharmacol Ther. 2012 Mar; 17(1):79-85. PMID: 21536855.
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    56. Goland S, Bitar F, Modi K, Safirstein J, Ro A, Mirocha J, Khatri N, Elkayam U. Evaluation of the clinical relevance of baseline left ventricular ejection fraction as a predictor of recovery or persistence of severe dysfunction in women in the United States with peripartum cardiomyopathy. J Card Fail. 2011 May; 17(5):426-30. PMID: 21549301.
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    57. Abraham WT, Aranda JM, Boehmer JP, Elkayam U, Gilbert EM, Gottlieb SS, Hasenfuss G, Kukin M, Lowes BD, O'Connell JB, Tavazzi L, Feldman AM, Ticho B, Orlandi C. Rationale and design of the treatment of hyponatremia based on lixivaptan in NYHA class III/IV cardiac patient evaluation (THE BALANCE) study. Clin Transl Sci. 2010 Oct; 3(5):249-53. PMID: 20973922.
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    58. Sliwa K, Hilfiker-Kleiner D, Petrie MC, Mebazaa A, Pieske B, Buchmann E, Regitz-Zagrosek V, Schaufelberger M, Tavazzi L, van Veldhuisen DJ, Watkins H, Shah AJ, Seferovic PM, Elkayam U, Pankuweit S, Papp Z, Mouquet F, McMurray JJ. Current state of knowledge on aetiology, diagnosis, management, and therapy of peripartum cardiomyopathy: a position statement from the Heart Failure Association of the European Society of Cardiology Working Group on peripartum cardiomyopathy. Eur J Heart Fail. 2010 Aug; 12(8):767-78. PMID: 20675664.
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    59. Giles TD, Elkayam U, Bhattacharya M, Perez A, Miller AB. Comparison of pioglitazone vs glyburide in early heart failure: insights from a randomized controlled study of patients with type 2 diabetes and mild cardiac disease. Congest Heart Fail. 2010 May-Jun; 16(3):111-7. PMID: 20557330.
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    60. Elkayam U, Goland S. Bromocriptine for the treatment of peripartum cardiomyopathy. Circulation. 2010 Apr 06; 121(13):1463-4. PMID: 20308620.
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    61. Goland S, Tsai F, Habib M, Janmohamed M, Goodwin TM, Elkayam U. Favorable outcome of pregnancy with an elective use of epoprostenol and sildenafil in women with severe pulmonary hypertension. Cardiology. 2010; 115(3):205-8. PMID: 20173324.
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    62. Ng TM, Tsai F, Khatri N, Barakat MN, Elkayam U. Venous thromboembolism in hospitalized patients with heart failure: incidence, prognosis, and prevention. Circ Heart Fail. 2010 Jan; 3(1):165-73. PMID: 20086221.
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    63. Falk RH, Elkayam U. Cardiomyopathy: the importance of recognizing the uncommon diagnosis. Prog Cardiovasc Dis. 2010 Jan-Feb; 52(4):262-3. PMID: 20109596.
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    64. Sarma RJ, Chana A, Elkayam U. Left ventricular noncompaction. Prog Cardiovasc Dis. 2010 Jan-Feb; 52(4):264-73. PMID: 20109597.
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    65. Metra M, Eichhorn E, Abraham WT, Linseman J, Böhm M, Corbalan R, DeMets D, De Marco T, Elkayam U, Gerber M, Komajda M, Liu P, Mareev V, Perrone SV, Poole-Wilson P, Roecker E, Stewart J, Swedberg K, Tendera M, Wiens B, Bristow MR. Effects of low-dose oral enoximone administration on mortality, morbidity, and exercise capacity in patients with advanced heart failure: the randomized, double-blind, placebo-controlled, parallel group ESSENTIAL trials. Eur Heart J. 2009 Dec; 30(24):3015-26. PMID: 19700774.
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    66. Cordasco KM, Asch SM, Bell DS, Guterman JJ, Gross-Schulman S, Ramer L, Elkayam U, Franco I, Leatherwood CL, Mangione CM. A low-literacy medication education tool for safety-net hospital patients. Am J Prev Med. 2009 Dec; 37(6 Suppl 1):S209-16. PMID: 19896021.
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    67. Goland S, Barakat M, Khatri N, Elkayam U. Pregnancy in Marfan syndrome: maternal and fetal risk and recommendations for patient assessment and management. Cardiol Rev. 2009 Nov-Dec; 17(6):253-62. PMID: 19829173.
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    68. Hameed AB, Chan K, Ghamsary M, Elkayam U. Longitudinal changes in the B-type natriuretic peptide levels in normal pregnancy and postpartum. Clin Cardiol. 2009 Aug; 32(8):E60-2. PMID: 19455566.
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    69. Elkayam U. Beta-blockers in the treatment of aortic regurgitation a new opportunity? J Am Coll Cardiol. 2009 Jul 28; 54(5):458-9. PMID: 19628122.
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    70. Goland S, Modi K, Bitar F, Janmohamed M, Mirocha JM, Czer LS, Illum S, Hatamizadeh P, Elkayam U. Clinical profile and predictors of complications in peripartum cardiomyopathy. J Card Fail. 2009 Oct; 15(8):645-50. PMID: 19786252.
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    71. Palardy M, Stevenson LW, Tasissa G, Hamilton MA, Bourge RC, Disalvo TG, Elkayam U, Hill JA, Reimold SC. Reduction in mitral regurgitation during therapy guided by measured filling pressures in the ESCAPE trial. Circ Heart Fail. 2009 May; 2(3):181-8. PMID: 19808338.
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    72. Elkayam U, Janmohamed M, Hatamizadeh P, Heywood JT, Wei LJ, Mills RM. Impact of acute serum creatinine elevation in patients treated with nesiritide. Clin Cardiol. 2009 Apr; 32(4):215-9. PMID: 19353723.
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    73. Goland S, Elkayam U. Cardiovascular problems in pregnant women with marfan syndrome. Circulation. 2009 Feb 03; 119(4):619-23. PMID: 19188522.
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    74. Gleicher N, Elkayam U. Peripartum cardiomyopathy, an autoimmune manifestation of allograft rejection? Autoimmun Rev. 2009 Mar; 8(5):384-7. PMID: 19087892.
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    75. Elkayam U, Akhter MW, Liu M, Hatamizadeh P, Barakat MN. Assessment of renal hemodynamic effects of nesiritide in patients with heart failure using intravascular Doppler and quantitative angiography. JACC Cardiovasc Imaging. 2008 Nov; 1(6):765-71. PMID: 19356514.
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    76. Puri P, Mehra A, Elkayam U. Cheyne-Stokes respiration and cardiac hemodynamics in heart failure. Catheter Cardiovasc Interv. 2008 Oct 01; 72(4):581-5. PMID: 18798251.
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    77. Roth A, Elkayam U. Acute myocardial infarction associated with pregnancy. J Am Coll Cardiol. 2008 Jul 15; 52(3):171-80. PMID: 18617065.
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    78. Goldsmith SR, Elkayam U, Haught WH, Barve A, He W. Efficacy and safety of the vasopressin V1A/V2-receptor antagonist conivaptan in acute decompensated heart failure: a dose-ranging pilot study. J Card Fail. 2008 Oct; 14(8):641-7. PMID: 18926434.
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    79. Giles TD, Miller AB, Elkayam U, Bhattacharya M, Perez A. Pioglitazone and heart failure: results from a controlled study in patients with type 2 diabetes mellitus and systolic dysfunction. J Card Fail. 2008 Aug; 14(6):445-52. PMID: 18672190.
      View in: PubMed
    80. Elkayam U, Ng TM, Hatamizadeh P, Janmohamed M, Mehra A. Renal Vasodilatory Action of Dopamine in Patients With Heart Failure: Magnitude of Effect and Site of Action. Circulation. 2008 Jan 15; 117(2):200-205. PMID: 18172028.
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    81. Elkayam U, Janmohamed M, Habib M, Hatamizadeh P. Vasodilators in the management of acute heart failure. Crit Care Med. 2008 Jan; 36(1 Suppl):S95-105. PMID: 18158484.
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    82. Hameed AB, Goodwin TM, Elkayam U. Effect of pulmonary stenosis on pregnancy outcomes--a case-control study. Am Heart J. 2007 Nov; 154(5):852-4. PMID: 17967589.
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    83. Elkayam U, Hatamizadeh P, Janmohamed M. The challenge of correcting volume overload in hospitalized patients with decompensated heart failure. J Am Coll Cardiol. 2007 Feb 13; 49(6):684-6. PMID: 17291933.
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    84. Elkayam U, Tasissa G, Binanay C, Stevenson LW, Gheorghiade M, Warnica JW, Young JB, Rayburn BK, Rogers JG, DeMarco T, Leier CV. Use and impact of inotropes and vasodilator therapy in hospitalized patients with severe heart failure. Am Heart J. 2007 Jan; 153(1):98-104. PMID: 17174645.
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    85. Payvar S, Orlandi C, Stough WG, Elkayam U, Ouyang J, Casscells SW, Gheorghiade M. Comparison of 60-day mortality in hospitalized heart failure patients with versus without hypothermia. Am J Cardiol. 2006 Dec 01; 98(11):1485-8. PMID: 17126655.
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    86. Bitar F, Lerman A, Akhter MW, Hatamizadeh P, Janmohamed M, Khan S, Elkayam U. Variable response of conductance and resistance coronary arteries to endothelial stimulation in patients with heart failure due to nonischemic dilated cardiomyopathy. J Cardiovasc Pharmacol Ther. 2006 Sep; 11(3):197-202. PMID: 17056833.
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    87. Sliwa K, Fett J, Elkayam U. Peripartum cardiomyopathy. Lancet. 2006 Aug 19; 368(9536):687-93. PMID: 16920474.
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    88. Tsai FS, Heidary S, Sarma R, Elkayam U. Safety of exercise testing in the chest pain unit: 31-mm ST elevation in variant angina. J Electrocardiol. 2006 Jul; 39(3):309. PMID: 16697394.
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    89. Elkayam U, Bitar F. Effects of nitrates and hydralazine in heart failure: clinical evidence before the african american heart failure trial. Am J Cardiol. 2005 Oct 10; 96(7B):37i-43i. PMID: 16226934.
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    90. Elkayam U, Bitar F. Valvular heart disease and pregnancy: part II: prosthetic valves. J Am Coll Cardiol. 2005 Aug 02; 46(3):403-10. PMID: 16053950.
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    91. Hameed A, Akhter MW, Bitar F, Khan SA, Sarma R, Goodwin TM, Elkayam U. Left atrial thrombosis in pregnant women with mitral stenosis and sinus rhythm. Am J Obstet Gynecol. 2005 Aug; 193(2):501-4. PMID: 16098877.
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    92. Elkayam U, Bitar F. Valvular heart disease and pregnancy part I: native valves. J Am Coll Cardiol. 2005 Jul 19; 46(2):223-30. PMID: 16022946.
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    93. Seshadri N, Goldhaber SZ, Elkayam U, Grimm RA, Groce JB, Heit JA, Spinler SA, Turpie AG, Bosker G, Klein AL. The clinical challenge of bridging anticoagulation with low-molecular-weight heparin in patients with mechanical prosthetic heart valves: an evidence-based comparative review focusing on anticoagulation options in pregnant and nonpregnant patients. Am Heart J. 2005 Jul; 150(1):27-34. PMID: 16084147.
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    94. Elkayam U, Akhter MW, Singh H, Khan S, Bitar F, Hameed A, Shotan A. Pregnancy-associated cardiomyopathy: clinical characteristics and a comparison between early and late presentation. Circulation. 2005 Apr 26; 111(16):2050-5. PMID: 15851613.
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    96. Gullestad L, Wikstrand J, Deedwania P, Hjalmarson A, Egstrup K, Elkayam U, Gottlieb S, Rashkow A, Wedel H, Bermann G, Kjekshus J. What resting heart rate should one aim for when treating patients with heart failure with a beta-blocker? Experiences from the Metoprolol Controlled Release/Extended Release Randomized Intervention Trial in Chronic Heart Failure (MERIT-HF). J Am Coll Cardiol. 2005 Jan 18; 45(2):252-9. PMID: 15653024.
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    97. Bitar F, Akhter MW, Khan S, Singh H, Elkayam U. Survey of the use of organic nitrates for the treatment of chronic congestive heart failure in the United States. Am J Cardiol. 2004 Dec 01; 94(11):1465-8. PMID: 15566930.
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    98. Elkayam U, Bitar F, Akhter MW, Khan S, Patrus S, Derakhshani M. Intravenous nitroglycerin in the treatment of decompensated heart failure: potential benefits and limitations. J Cardiovasc Pharmacol Ther. 2004 Dec; 9(4):227-41. PMID: 15678242.
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    99. Akhter MW, Aronson D, Bitar F, Khan S, Singh H, Singh RP, Burger AJ, Elkayam U. Effect of elevated admission serum creatinine and its worsening on outcome in hospitalized patients with decompensated heart failure. Am J Cardiol. 2004 Oct 01; 94(7):957-60. PMID: 15464689.
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    100. Qasqas SA, McPherson C, Frishman WH, Elkayam U. Cardiovascular pharmacotherapeutic considerations during pregnancy and lactation. Cardiol Rev. 2004 Sep-Oct; 12(5):240-61. PMID: 15316305.
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    101. Qasqas SA, McPherson C, Frishman WH, Elkayam U. Cardiovascular pharmacotherapeutic considerations during pregnancy and lactation. Cardiol Rev. 2004 Jul-Aug; 12(4):201-21. PMID: 15191632.
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    102. Elkayam U, Singh H, Irani A, Akhter MW. Anticoagulation in pregnant women with prosthetic heart valves. J Cardiovasc Pharmacol Ther. 2004 Jun; 9(2):107-15. PMID: 15309247.
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    103. Gheorghiade M, Gattis WA, O'Connor CM, Adams KF, Elkayam U, Barbagelata A, Ghali JK, Benza RL, McGrew FA, Klapholz M, Ouyang J, Orlandi C. Effects of tolvaptan, a vasopressin antagonist, in patients hospitalized with worsening heart failure: a randomized controlled trial. JAMA. 2004 Apr 28; 291(16):1963-71. PMID: 15113814.
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    104. Elkayam U, Akhter MW, Singh H, Khan S, Usman A. Comparison of effects on left ventricular filling pressure of intravenous nesiritide and high-dose nitroglycerin in patients with decompensated heart failure. Am J Cardiol. 2004 Jan 15; 93(2):237-40. PMID: 14715359.
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    105. Canetti M, Akhter MW, Lerman A, Karaalp IS, Zell JA, Singh H, Mehra A, Elkayam U. Evaluation of myocardial blood flow reserve in patients with chronic congestive heart failure due to idiopathic dilated cardiomyopathy. Am J Cardiol. 2003 Nov 15; 92(10):1246-9. PMID: 14609613.
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    106. Torre-Amione G, Young JB, Colucci WS, Lewis BS, Pratt C, Cotter G, Stangl K, Elkayam U, Teerlink JR, Frey A, Rainisio M, Kobrin I. Hemodynamic and clinical effects of tezosentan, an intravenous dual endothelin receptor antagonist, in patients hospitalized for acute decompensated heart failure. J Am Coll Cardiol. 2003 Jul 02; 42(1):140-7. PMID: 12849674.
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    107. Gheorghiade M, Gattis WA, Barbagelata A, Adams KF, Elkayam U, Orlandi C, O'Connor CM. Rationale and study design for a multicenter, randomized, double-blind, placebo-controlled study of the effects of tolvaptan on the acute and chronic outcomes of patients hospitalized with worsening congestive heart failure. Am Heart J. 2003 Feb; 145(2 Suppl):S51-4. PMID: 12594452.
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    108. Burger AJ, Horton DP, LeJemtel T, Ghali JK, Torre G, Dennish G, Koren M, Dinerman J, Silver M, Cheng ML, Elkayam U. Effect of nesiritide (B-type natriuretic peptide) and dobutamine on ventricular arrhythmias in the treatment of patients with acutely decompensated congestive heart failure: the PRECEDENT study. Am Heart J. 2002 Dec; 144(6):1102-8. PMID: 12486437.
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    109. Elkayam U, Akhter MW, Tummala P, Khan S, Singh H. Nesiritide: a new drug for the treatment of decompensated heart failure. J Cardiovasc Pharmacol Ther. 2002 Jul; 7(3):181-94. PMID: 12232567.
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    110. Silver MA, Horton DP, Ghali JK, Elkayam U. Effect of nesiritide versus dobutamine on short-term outcomes in the treatment of patients with acutely decompensated heart failure. J Am Coll Cardiol. 2002 Mar 06; 39(5):798-803. PMID: 11869844.
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    111. Elkayam U, Khan S, Mehboob A, Ahsan N. Impaired endothelium-mediated vasodilation in heart failure: clinical evidence and the potential for therapy. J Card Fail. 2002 Feb; 8(1):15-20. PMID: 11862578.
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    112. Elkayam U, Prakash M, Subbiah S, Mehdi S, Nikitina A, Akhter W. Endothelial function in patients with chronic heart failure. J Cardiovasc Pharmacol. 2001 Nov; 38 Suppl 2:S47-8. PMID: 11811377.
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    113. Elkayam U, Tummala PP, Rao K, Akhter MW, Karaalp IS, Wani OR, Hameed A, Gviazda I, Shotan A. Maternal and fetal outcomes of subsequent pregnancies in women with peripartum cardiomyopathy. N Engl J Med. 2001 May 24; 344(21):1567-71. PMID: 11372007.
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    114. Hameed A, Karaalp IS, Tummala PP, Wani OR, Canetti M, Akhter MW, Goodwin I, Zapadinsky N, Elkayam U. The effect of valvular heart disease on maternal and fetal outcome of pregnancy. J Am Coll Cardiol. 2001 Mar 01; 37(3):893-9. PMID: 11693767.
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    115. Hameed AB, Tummala PP, Goodwin TM, Nuno I, Wani OR, Karaalp IS, Elkayam U. Unstable angina during pregnancy in two patients with premature coronary atherosclerosis and aortic stenosis in association with familial hypercholesterolemia. Am J Obstet Gynecol. 2000 May; 182(5):1152-5. PMID: 10819851.
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    116. Elkayam U, Johnson JV, Shotan A, Bokhari S, Solodky A, Canetti M, Wani OR, Karaalp IS. Double-blind, placebo-controlled study to evaluate the effect of organic nitrates in patients with chronic heart failure treated with angiotensin-converting enzyme inhibition. Circulation. 1999 May 25; 99(20):2652-7. PMID: 10338458.
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    117. Elkayam U, Karaalp IS, Wani OR, Tummala P, Akhter MW. The role of organic nitrates in the treatment of heart failure. Prog Cardiovasc Dis. 1999 Jan-Feb; 41(4):255-64. PMID: 10362348.
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    118. Goodwin TM, Gherman RB, Hameed A, Elkayam U. Favorable response of Eisenmenger syndrome to inhaled nitric oxide during pregnancy. Am J Obstet Gynecol. 1999 Jan; 180(1 Pt 1):64-7. PMID: 9914580.
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    119. Hurst AK, Shotan A, Hoffman K, Johnson J, Goodwin TM, Koda R, Elkayam U. Pharmacokinetic and pharmacodynamic evaluation of atenolol during and after pregnancy. Pharmacotherapy. 1998 Jul-Aug; 18(4):840-6. PMID: 9692658.
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    120. Elkayam U, Mehra A, Cohen G, Tummala PP, Karaalp IS, Wani OR, Canetti M. Renal circulatory effects of adenosine in patients with chronic heart failure. J Am Coll Cardiol. 1998 Jul; 32(1):211-5. PMID: 9669272.
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    121. Elkayam U. Calcium channel blockers in heart failure. Cardiology. 1998; 89 Suppl 1:38-46. PMID: 9570428.
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    122. Shotan A, Ostrzega E, Mehra A, Johnson JV, Elkayam U. Incidence of arrhythmias in normal pregnancy and relation to palpitations, dizziness, and syncope. Am J Cardiol. 1997 Apr 15; 79(8):1061-4. PMID: 9114764.
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    123. Elkayam U, Cohen G, Gogia H, Mehra A, Johnson JV, Chandraratna PA. Renal vasodilatory effect of endothelial stimulation in patients with chronic congestive heart failure. J Am Coll Cardiol. 1996 Jul; 28(1):176-82. PMID: 8752811.
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    124. Elkayam UR. Anticoagulation in pregnant women with prosthetic heart valves: a double jeopardy. J Am Coll Cardiol. 1996 Jun; 27(7):1704-6. PMID: 8636557.
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    125. Elkayam U. Nitrates in the treatment of congestive heart failure. Am J Cardiol. 1996 May 30; 77(13):41C-51C. PMID: 8638526.
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    126. Elkayam U. Prevention of nitrate tolerance with concomitant administration of hydralazine. Can J Cardiol. 1996 May; 12 Suppl C:17C-21C. PMID: 8634919.
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    127. Gogia H, Mehra A, Parikh S, Raman M, Ajit-Uppal J, Johnson JV, Elkayam U. Prevention of tolerance to hemodynamic effects of nitrates with concomitant use of hydralazine in patients with chronic heart failure. J Am Coll Cardiol. 1995 Dec; 26(7):1575-80. PMID: 7594088.
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    128. Mehra A, Shotan A, Ostrzega E, Vasquez-Johnson J, Elkayam U. Escalating nitrate dose overcomes early attenuation of hemodynamic effect caused by nitrate tolerance in patients with heart failure. Am Heart J. 1995 Oct; 130(4):798-805. PMID: 7572589.
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    129. Elkayam U, Ostrzega E, Shotan A, Mehra A. Cardiovascular problems in pregnant women with the Marfan syndrome. Ann Intern Med. 1995 Jul 15; 123(2):117-22. PMID: 7778824.
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    130. Elkayam U, Goodwin TM. Adenosine therapy for supraventricular tachycardia during pregnancy. Am J Cardiol. 1995 Mar 01; 75(7):521-3. PMID: 7864004.
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    131. Keung YK, Lau S, Elkayam U, Chen SC, Douer D. Cardiac arrhythmia after infusion of cryopreserved stem cells. Bone Marrow Transplant. 1994 Sep; 14(3):363-7. PMID: 7994256.
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    132. Mehra A, Shotan A, Ostrzega E, Hsueh W, Vasquez-Johnson J, Elkayam U. Potentiation of isosorbide dinitrate effects with N-acetylcysteine in patients with chronic heart failure. Circulation. 1994 Jun; 89(6):2595-600. PMID: 8205670.
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    133. Shotan A, Widerhorn J, Hurst A, Elkayam U. Risks of angiotensin-converting enzyme inhibition during pregnancy: experimental and clinical evidence, potential mechanisms, and recommendations for use. Am J Med. 1994 May; 96(5):451-6. PMID: 8192177.
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    134. Elkayam U. Nitrates in heart failure. Cardiol Clin. 1994 Feb; 12(1):73-85. PMID: 8181027.
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    135. Shotan A, Mehra A, Ostrzega E, Hsueh W, Do YS, Fisher DA, Hurst A, Johnson JV, Elkayam U. Plasma cyclic guanosine monophosphate in chronic heart failure: hemodynamic and neurohormonal correlations and response to nitrate therapy. Clin Pharmacol Ther. 1993 Dec; 54(6):638-44. PMID: 7903916.
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    136. Elkayam U, Shotan A, Mehra A, Ostrzega E. Calcium channel blockers in heart failure. J Am Coll Cardiol. 1993 Oct; 22(4 Suppl A):139A-144A. PMID: 8376684.
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    137. Roth A, Shotan A, Elkayam U. A randomized comparison between the hemodynamic effects of hydralazine and nitroglycerin alone and in combination at rest and during isometric exercise in patients with chronic mitral regurgitation. Am Heart J. 1993 Jan; 125(1):155-63. PMID: 8417512.
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    138. Elkayam U, Mehra A, Shotan A, Osprzega E. Possible mechanisms of nitrate tolerance. Am J Cardiol. 1992 Nov 27; 70(17):49G-53G; discussion 53G-54G. PMID: 1449100.
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    139. Mehra A, Ostrzega E, Shotan A, Johnson JV, Elkayam U. Persistent hemodynamic improvement with short-term nitrate therapy in patients with chronic congestive heart failure already treated with captopril. Am J Cardiol. 1992 Nov 15; 70(15):1310-4. PMID: 1442583.
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    140. Elkayam U, Mehra A, Shotan A, Ostrzega E. Nitrate resistance and tolerance: potential limitations in the treatment of congestive heart failure. Am J Cardiol. 1992 Sep 24; 70(8):98B-104B. PMID: 1529933.
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    141. Widerhorn J, Widerhorn AL, Rahimtoola SH, Elkayam U. WPW syndrome during pregnancy: increased incidence of supraventricular arrhythmias. Am Heart J. 1992 Mar; 123(3):796-8. PMID: 1539536.
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    142. Elkayam U, Roth A, Mehra A, Ostrzega E, Shotan A, Kulick D, Jamison M, Johnston JV, Rahimtoola SH. Randomized study to evaluate the relation between oral isosorbide dinitrate dosing interval and the development of early tolerance to its effect on left ventricular filling pressure in patients with chronic heart failure. Circulation. 1991 Nov; 84(5):2040-8. PMID: 1934379.
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    143. Widerhorn J, Bhandari AK, Bughi S, Rahimtoola SH, Elkayam U. Fetal and neonatal adverse effects profile of amiodarone treatment during pregnancy. Am Heart J. 1991 Oct; 122(4 Pt 1):1162-6. PMID: 1927869.
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    144. Elkayam U. Tolerance to organic nitrates: evidence, mechanisms, clinical relevance, and strategies for prevention. Ann Intern Med. 1991 Apr 15; 114(8):667-77. PMID: 2003715.
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    145. Elkayam U, Amin J, Mehra A, Vasquez J, Weber L, Rahimtoola SH. A prospective, randomized, double-blind, crossover study to compare the efficacy and safety of chronic nifedipine therapy with that of isosorbide dinitrate and their combination in the treatment of chronic congestive heart failure. Circulation. 1990 Dec; 82(6):1954-61. PMID: 2242521.
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    146. Elkayam U. Can prognosis be altered by treating LV dysfunction? Clin Cardiol. 1989 Jul; 12(7 Suppl 3):III58-64. PMID: 2575022.
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    147. Jamison M, Widerhorn J, Weber L, Campese V, Vasquez J, Hovanessian L, Rahimtoola SH, Elkayam U. Central and renal hemodynamic effects of a new agonist at peripheral dopamine- and beta-2 adrenoreceptors (dopexamine) in patients with heart failure. Am Heart J. 1989 Mar; 117(3):607-14. PMID: 2537556.
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    148. Kulick D, Roth A, McIntosh N, Rahimtoola SH, Elkayam U. Resistance to isosorbide dinitrate in patients with severe chronic heart failure: incidence and attempt at hemodynamic prediction. J Am Coll Cardiol. 1988 Oct; 12(4):1023-8. PMID: 3417975.
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    149. Kulick DL, Hong R, Ryzen E, Rude RK, Rubin JN, Elkayam U, Rahimtoola SH, Bhandari AK. Electrophysiologic effects of intravenous magnesium in patients with normal conduction systems and no clinical evidence of significant cardiac disease. Am Heart J. 1988 Feb; 115(2):367-73. PMID: 3341171.
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    150. Elkayam U, Roth A, Kumar A, Kulick D, McIntosh N, McKay CR, Rahimtoola SH. Hemodynamic and volumetric effects of venodilation with nitroglycerin in chronic mitral regurgitation. Am J Cardiol. 1987 Nov 01; 60(13):1106-11. PMID: 3118694.
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    151. Widerhorn J, Rubin JN, Frishman WH, Elkayam U. Cardiovascular drugs in pregnancy. Cardiol Clin. 1987 Nov; 5(4):651-74. PMID: 2900070.
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