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Immunopathology of immune thrombocytopenia. J Thromb Haemost. 2026 Feb 09.
Hillier K, Kim TO, Pincez T. PMID: 41672375.
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Predicting Development of Pediatric Chronic Immune Thrombocytopenia at Disease Onset Using a Statistical Risk Model. Blood. 2026 Feb 03.
Hillier K, Zobeck M, MacMath D, Chumsky J, Kirk SE, O'Farrell C, Lucari B, Ngwerume F, Gaerlan S, Konde P, Wang KG, Lambert MP, Grace RF, Grimes AB, Kim TO. PMID: 41632829.
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Pediatric Evans Syndrome Diagnostic Evaluation Patterns: Survey Results From the Pediatric ITP Consortium of North America. Pediatr Blood Cancer. 2026 Apr; 73(4):e70121.
Kim TO, Hillier K, Gunn E, Badawy SM, Grimes AB, Gilbert M, Remiker A, Lilla SAF, Kaicker S, Lambert MP, Grace RF, Terrell DR. PMID: 41518117.
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Translation:
Humans
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Eltrombopag for Newly Diagnosed Pediatric Immune Thrombocytopenia Requiring Treatment: The PINES Randomized Clinical Trial. JAMA. 2025 11 25; 334(20):1816-1826.
Shimano KA, Grimes AB, Kaicker S, Shah SJ, Gunn E, Bhat RV, Kochhar M, Rothman JA, Rose MJ, Briones M, Nakano TA, Lebensburger JD, Lambert MP, Fritch Lilla SA, Jesudas R, Lee-Miller CA, Thompson AA, Rifkin-Zenenberg S, Majumdar S, Crary SE, Hege K, Ford JB, Bies JJ, Fort J, Wynn TT, Hsieh L, Ruiz ME, Dinu B, Wong JMW, Kao PC, Kim TO, Arnold SD, Bennett CM, Despotovic JM, Klaassen RJ, Neufeld EJ, Neunert CE, London WB, Grace RF. PMID: 41123939; PMCID: PMC12547676.
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HumansCTClinical Trials
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Ubiquitous dysregulation of the Wnt pathway in immune thrombocytopenia genetic susceptibility. Blood Vessel Thromb Hemost. 2025 Nov; 2(4):100107.
Lecluze E, Da Silva Faria S, Saby M, Yu J, Lisi V, Lavallée VP, Kim TO, Scheurer ME, Grimes AB, Pincez T. PMID: 41235340; PMCID: PMC12607065.
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Genetic variants in canonical Wnt signaling pathway associated with pediatric immune thrombocytopenia. Blood Adv. 2024 11 12; 8(21):5529-5538.
Kim TO, Geris JM, Flanagan JM, Grace RF, Lambert MP, O'Farrell C, Rose MJ, Shimano KA, Niss O, Neunert C, Nakano TA, MacMath D, Dinu B, Kirk SE, Neufeld EJ, Despotovic JM, Scheurer ME, Grimes AB. PMID: 39189922; PMCID: PMC11538615.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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What is in a name: defining pediatric refractory ITP. Blood Adv. 2024 10 08; 8(19):5112-5117.
Nakano TA, Grimes AB, Klaassen RJ, Lambert MP, Neunert C, Rothman JA, Shimano KA, Amend C, Askew M, Badawy SM, Baker JM, Breakey V, Crary S, Davini M, Fritch Lilla S, Gilbert M, Hays T, Hege K, Hillier K, Jacobson-Kelly A, Kaicker S, Kim TO, Kochhar M, Leblanc T, Martinelli M, Nunez M, Remiker A, Schultz C, Sharma R, Grace RF. PMID: 39059013; PMCID: PMC11460440.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Immunoglobulins act as predictors of chronicity in pediatric immune thrombocytopenia. Blood Adv. 2024 10 08; 8(19):5118-5121.
Hillier K, MacMath D, Chumsky J, Kirk SE, O'Farrell C, Kim TO, Zobeck M, Grimes AB. PMID: 38935889; PMCID: PMC11460450.
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Humans
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Detection of novel duplication variant in ADAMTS13 gene using chromosomal microarray analysis. BMJ Case Rep. 2024 Jun 11; 17(6).
Helber HL, Kim TO, Han H. PMID: 38862189.
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Humans
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Pediatric autoimmune myelofibrosis: Experience from a large pediatric tertiary care center. Pediatr Blood Cancer. 2023 04; 70(4):e30144.
Kim TO, Curry CV, Wiszniewska J, Elghetany MT, Satter LRF, Grimes AB, Despotovic JM. PMID: 36661251.
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Humans
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Cold AIHA and the best treatment strategies. Hematology Am Soc Hematol Educ Program. 2022 12 09; 2022(1):90-95.
Despotovic JM, Kim TO. PMID: 36485161; PMCID: PMC9821124.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Risk factors and prognostic significance of platelet count abnormalities in children with HIV infection on antiretroviral therapy. AIDS. 2023 03 01; 37(3):413-421.
Lubega J, Kim TO, Airewele G, Grimes A, Bulsara S, Peckham E, Wanless SR, Haq H, Elyanu P, Musoke P, Lumumba M, Kekitiinwa A, Matshaba M, Scheurer M, Despotovic J. PMID: 36129118; PMCID: PMC9877116.
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Translation:
Humans
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Risk factors and prognostic significance of anemia in children with HIV infection on antiretroviral therapy. AIDS. 2022 12 01; 36(15):2139-2146.
Lubega J, Grimes A, Airewele G, Bulsara S, Kim TO, Haq H, Peckham-Gregory E, Wanless SR, Elyanu P, Musoke P, Lumumba M, Kekitiinwa A, Matshaba M, Despotovic J, Scheurer M. PMID: 36052537; PMCID: PMC9671853.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Spinal cord compression: An unusual sequela of sickle cell disease. Pediatr Blood Cancer. 2022 Nov; 69(11):e29709.
Shekar M, Casini G, Donoho D, Mohila C, Kim TO, Fasipe T, Porea T. PMID: 35373914.
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Immune cells surveil aberrantly sialylated O-glycans on megakaryocytes to regulate platelet count. Blood. 2021 12 09; 138(23):2408-2424.
Lee-Sundlov MM, Burns RT, Kim TO, Grozovsky R, Giannini S, Rivadeneyra L, Zheng Y, Glabere SH, Kahr WHA, Abdi R, Despotovic JM, Wang D, Hoffmeister KM. PMID: 34324649; PMCID: PMC8662070.
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PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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COVID-19 outcomes in a large pediatric hematology-oncology center in Houston, Texas. Pediatr Hematol Oncol. 2021 Nov; 38(8):695-706.
Kamdar KY, Kim TO, Doherty EE, Pfeiffer TM, Qasim SL, Suell MN, Yates AM, Blaney SM. PMID: 34032552.
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Refractory autoimmune cytopenias in pediatric Evans syndrome with underlying systemic immune dysregulation. Eur J Haematol. 2021 Jun; 106(6):783-787.
Grimes AB, Kim TO, Kirk SE, Flanagan J, Lambert MP, Grace RF, Despotovic JM. PMID: 33570766.
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Racial variation in ITP prevalence and chronic disease phenotype suggests biological differences. Blood. 2020 07 30; 136(5):640-643.
Kim TO, Grimes AB, Kirk SE, Gilbert MM, Reed HD, Staggers KA, Walker LA, Arulselvan A, Cohen AS, Lambert MP, Despotovic JM. PMID: 32559763; PMCID: PMC8212348.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Romiplostim for the Treatment of Immune Thrombocytopenia: Spotlight on Patient Acceptability and Ease of Use. Patient Prefer Adherence. 2020; 14:1237-1250.
Gilbert MM, Grimes AB, Kim TO, Despotovic JM. PMID: 32801654; PMCID: PMC7383044.
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PubMed Mentions:
5
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Genetic variants in toll-like receptor 4 are associated with lack of steroid-responsiveness in pediatric ITP patients. Am J Hematol. 2020 04; 95(4):395-400.
Kim TO, Flanagan JM, Habibi A, Arulselvan A, Lambert MP, Grace RF, Despotovic JM. PMID: 31903617.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Common variable immunodeficiency-associated endotoxemia promotes early commitment to the T follicular lineage. J Allergy Clin Immunol. 2019 12; 144(6):1660-1673.
Le Coz C, Bengsch B, Khanna C, Trofa M, Ohtani T, Nolan BE, Henrickson SE, Lambert MP, Kim TO, Despotovic JM, Feldman S, Fadugba OO, Takach P, Ruffner M, Jyonouchi S, Heimall J, Sullivan KE, Wherry EJ, Romberg N. PMID: 31445098; PMCID: PMC6900457.
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PubMed Mentions:
18 Fields:
Translation:
HumansCellsCTClinical Trials
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Primary and Secondary Immune Cytopenias: Evaluation and Treatment Approach in Children. Hematol Oncol Clin North Am. 2019 06; 33(3):489-506.
Kim TO, Despotovic JM. PMID: 31030815.
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11 Fields:
Translation:
Humans
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Association of a positive direct antiglobulin test with chronic immune thrombocytopenia and use of second line therapies in children: A multi-institutional review. Am J Hematol. 2019 04; 94(4):461-466.
Kim TO, Grimes AB, Kirk S, Arulselvan A, Lambert MP, Grace RF, Despotovic JM. PMID: 30663792.
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PubMed Mentions:
3 Fields:
Translation:
HumansCTClinical Trials
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Eltrombopag for use in children with immune thrombocytopenia. Blood Adv. 2018 02 27; 2(4):454-461.
Kim TO, Despotovic J, Lambert MP. PMID: 29487060; PMCID: PMC5858473.
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PubMed Mentions:
42 Fields:
Translation:
Humans