Stanford S Jhee

Title(s)Adjunct Assistant Professor
SchoolUSC School of Pharmacy
Address1540 Alcazar Street
Health Sciences Campus
Los Angeles CA 90033
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Robust Pharmacodynamic Effect of LY3202626, a Central Nervous System Penetrant, Low Dose BACE1 Inhibitor, in Humans and Nonclinical Species. J Alzheimers Dis Rep. 2022; 6(1):1-15. Willis BA, Lowe SL, Monk SA, Cocke PJ, Aluise CD, Boggs LN, Borders AR, Brier RA, Dean RA, Green SJ, James DE, Jhee SS, Lin Q, Lo AC, May PC, Watson BM, Winneroski LL, Yang Z, Zimmer JA, McKinzie DL, Mergott DJ. PMID: 35243208; PMCID: PMC8842743.
      View in: PubMed   Mentions:
    2. A Randomized, Double-Blind, Placebo- and Active-Controlled, Escalating Single-Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Profiles of Subcutaneous Eflapegrastim in Healthy Japanese and Caucasian Subjects. Drugs R D. 2022 Mar; 22(1):71-87. Jeon Y, Lee N, Baek S, Choi J, Jhee S, Lee H. PMID: 34993933; PMCID: PMC8885935.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    3. A first-in-human study to investigate the safety, tolerability, pharmacokinetics, and pharmacodynamics of KM-819 (FAS-associated factor 1 inhibitor), a drug for Parkinson's disease, in healthy volunteers. Drug Des Devel Ther. 2019; 13:1011-1022. Shin W, Lim KS, Kim MK, Kim HS, Hong J, Jhee S, Kim J, Yoo S, Chung YT, Lee JM, Cho DY. PMID: 30992659; PMCID: PMC6445238.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    4. Implementing a Memory Clinic Model to Facilitate Recruitment into Early Phase Clinical Trials for Mild Cognitive Impairment and Alzheimer's Disease. J Prev Alzheimers Dis. 2019; 6(2):135-138. Park L, Kouhanim C, Lee S, Mendoza Z, Patrick K, Gertsik L, Aguilar C, Gullaba D, Semenova S, Jhee S. PMID: 30756120.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Evaluation of the single-dose pharmacokinetics and pharmacodynamics of apixaban in healthy Japanese and Caucasian subjects. Clin Pharmacol. 2018; 10:153-163. Frost C, Shenker A, Jhee S, Yu Z, Wang J, Bragat A, Pursley J, LaCreta F. PMID: 30498375; PMCID: PMC6207247.
      View in: PubMed   Mentions: 2  
    6. Dihydroxyphenylglycol as a Biomarker of Norepinephrine Transporter Inhibition by Atomoxetine: Human Model to Assess Central and Peripheral Effects of Dosing. J Clin Psychopharmacol. 2016 Dec; 36(6):675-683. Bieck PR, Leibowitz M, Lachno DR, Ledent E, Padich R, Jhee S. PMID: 27755221.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    7. The BACE1 inhibitor verubecestat (MK-8931) reduces CNS β-amyloid in animal models and in Alzheimer's disease patients. Sci Transl Med. 2016 11 02; 8(363):363ra150. Kennedy ME, Stamford AW, Chen X, Cox K, Cumming JN, Dockendorf MF, Egan M, Ereshefsky L, Hodgson RA, Hyde LA, Jhee S, Kleijn HJ, Kuvelkar R, Li W, Mattson BA, Mei H, Palcza J, Scott JD, Tanen M, Troyer MD, Tseng JL, Stone JA, Parker EM, Forman MS. PMID: 27807285.
      View in: PubMed   Mentions: 135     Fields:    Translation:AnimalsCells
    8. Effects of the glycine reuptake inhibitors bitopertin and RG7118 on glycine in cerebrospinal fluid: results of two proofs of mechanism studies in healthy volunteers. Psychopharmacology (Berl). 2016 07; 233(13):2429-39. Hofmann C, Pizzagalli F, Boetsch C, Alberati D, Ereshefsky L, Jhee S, Patat A, Boutouyrie-Dumont B, Martin-Facklam M. PMID: 27178435.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    9. The effect of LCZ696 (sacubitril/valsartan) on amyloid-β concentrations in cerebrospinal fluid in healthy subjects. Br J Clin Pharmacol. 2016 May; 81(5):878-90. Langenickel TH, Tsubouchi C, Ayalasomayajula S, Pal P, Valentin MA, Hinder M, Jhee S, Gevorkyan H, Rajman I. PMID: 26663387; PMCID: PMC4834603.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    10. The potent BACE1 inhibitor LY2886721 elicits robust central Aβ pharmacodynamic responses in mice, dogs, and humans. J Neurosci. 2015 Jan 21; 35(3):1199-210. May PC, Willis BA, Lowe SL, Dean RA, Monk SA, Cocke PJ, Audia JE, Boggs LN, Borders AR, Brier RA, Calligaro DO, Day TA, Ereshefsky L, Erickson JA, Gevorkyan H, Gonzales CR, James DE, Jhee SS, Komjathy SF, Li L, Lindstrom TD, Mathes BM, Martényi F, Sheehan SM, Stout SL, Timm DE, Vaught GM, Watson BM, Winneroski LL, Yang Z, Mergott DJ. PMID: 25609634; PMCID: PMC6605527.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimals
    11. Peripheral and central nervous system inhibition of 11β-hydroxysteroid dehydrogenase type 1 in man by the novel inhibitor ABT-384. Transl Psychiatry. 2013 Aug 27; 3:e295. Katz DA, Liu W, Locke C, Jacobson P, Barnes DM, Basu R, An G, Rieser MJ, Daszkowski D, Groves F, Heneghan G, Shah A, Gevorkyan H, Jhee SS, Ereshefsky L, Marek GJ. PMID: 23982627; PMCID: PMC3756293.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    12. Pharmacokinetic Profile of Orally Administered Scyllo-Inositol (Elnd005) in Plasma, Cerebrospinal Fluid and Brain, and Corresponding Effect on Amyloid-Beta in Healthy Subjects. Clin Pharmacol Drug Dev. 2013 Apr; 2(2):186-94. Liang E, Garzone P, Cedarbaum JM, Koller M, Tran T, Xu V, Ross B, Jhee SS, Ereshefsky L, Pastrak A, Abushakra S. PMID: 27121673.
      View in: PubMed   Mentions: 5     Fields:    
    13. Clinically significant psychotropic drug-drug interactions in the primary care setting. Curr Psychiatry Rep. 2012 Aug; 14(4):376-90. English BA, Dortch M, Ereshefsky L, Jhee S. PMID: 22707017; PMCID: PMC4335312.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    14. Robust central reduction of amyloid-β in humans with an orally available, non-peptidic β-secretase inhibitor. J Neurosci. 2011 Nov 16; 31(46):16507-16. May PC, Dean RA, Lowe SL, Martenyi F, Sheehan SM, Boggs LN, Monk SA, Mathes BM, Mergott DJ, Watson BM, Stout SL, Timm DE, Smith Labell E, Gonzales CR, Nakano M, Jhee SS, Yen M, Ereshefsky L, Lindstrom TD, Calligaro DO, Cocke PJ, Greg Hall D, Friedrich S, Citron M, Audia JE. PMID: 22090477; PMCID: PMC6633289.
      View in: PubMed   Mentions: 137     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    15. Effect of human cerebrospinal fluid sampling frequency on amyloid-β levels. Alzheimers Dement. 2012 Jul; 8(4):295-303. Li J, Llano DA, Ellis T, LeBlond D, Bhathena A, Jhee SS, Ereshefsky L, Lenz R, Waring JF. PMID: 22047633.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    16. Cerebrospinal fluid beta-amyloid and dynabridging in Alzheimer's disease drug development. Biomark Med. 2009 Dec; 3(6):711-21. Ereshefsky L, Jhee S, Yen M, Moran S, Pretorius S, Adams J. PMID: 20477709.
      View in: PubMed   Mentions: 4     Fields:    
    17. Low penetration of oseltamivir and its carboxylate into cerebrospinal fluid in healthy Japanese and Caucasian volunteers. Antimicrob Agents Chemother. 2008 Oct; 52(10):3687-93. Jhee SS, Yen M, Ereshefsky L, Leibowitz M, Schulte M, Kaeser B, Boak L, Patel A, Hoffmann G, Prinssen EP, Rayner CR. PMID: 18676886; PMCID: PMC2565879.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    18. Pharmacokinetics and pharmacodynamics of the novel daily rivastigmine transdermal patch compared with twice-daily capsules in Alzheimer's disease patients. Clin Pharmacol Ther. 2008 Jan; 83(1):106-14. Lefèvre G, Sedek G, Jhee SS, Leibowitz MT, Huang HL, Enz A, Maton S, Ereshefsky L, Pommier F, Schmidli H, Appel-Dingemanse S. PMID: 17522596.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    19. Identifying pharmacodynamic protein markers of centrally active drugs in humans: a pilot study in a novel clinical model. J Proteome Res. 2007 Mar; 6(3):955-66. Patil ST, Higgs RE, Brandt JE, Knierman MD, Gelfanova V, Butler JP, Downing AM, Dorocke J, Dean RA, Potter WZ, Michelson D, Pan AX, Jhee SS, Hale JE. PMID: 17243662.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    20. Multiple-dose plasma pharmacokinetic and safety study of LY450108 and LY451395 (AMPA receptor potentiators) and their concentration in cerebrospinal fluid in healthy human subjects. J Clin Pharmacol. 2006 Apr; 46(4):424-32. Jhee SS, Chappell AS, Zarotsky V, Moran SV, Rosenthal M, Kim E, Chalon S, Toublanc N, Brandt J, Coutant DE, Ereshefsky L. PMID: 16554450.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    21. Antidepressant drug-drug interaction profile update. Drugs R D. 2005; 6(6):323-36. Ereshefsky L, Jhee S, Grothe D. PMID: 16274257.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    22. Similarity of insulin detemir pharmacokinetics, safety, and tolerability profiles in healthy caucasian and Japanese american subjects. J Clin Pharmacol. 2004 Mar; 44(3):258-64. Jhee SS, Lyness WH, Rojas PB, Leibowitz MT, Zarotsky V, Jacobsen LV. PMID: 14973299.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    23. Delayed onset of oculogyric crisis and torticollis with intramuscular haloperidol. Ann Pharmacother. 2003 Oct; 37(10):1434-7. Jhee SS, Zarotsky V, Mohaupt SM, Yones CL, Sims SJ. PMID: 14519055.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    24. First clinical evaluation of ganstigmine in patients with probable Alzheimer's disease. Clin Neuropharmacol. 2003 May-Jun; 26(3):164-9. Jhee SS, Fabbri L, Piccinno A, Monici P, Moran S, Zarotsky V, Tan EY, Frackiewicz EJ, Shiovitz T. PMID: 12782920.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    25. Centrally acting antiemetics mitigate nausea and vomiting in patients with Alzheimer's disease who receive rivastigmine. Clin Neuropharmacol. 2002 Mar-Apr; 25(2):122-3. Jhee SS, Shiovitz T, Hartman RD, Messina J, Anand R, Sramek J, Cutler NR. PMID: 11981242.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    26. Brasofensine treatment for Parkinson's disease in combination with levodopa/carbidopa. Ann Pharmacother. 2002 Feb; 36(2):225-30. Frackiewicz EJ, Jhee SS, Shiovitz TM, Webster J, Topham C, Dockens RC, Whigan D, Salazar DE, Cutler NR. PMID: 11847938.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCTClinical Trials
    27. Estimation of the absolute bioavailability of rivastigmine in patients with mild to moderate dementia of the Alzheimer's type. Clin Pharmacokinet. 2002; 41(3):225-34. Hossain M, Jhee SS, Shiovitz T, McDonald C, Sedek G, Pommier F, Cutler NR. PMID: 11929322.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCTClinical Trials
    28. Pharmacokinetic-pharmacodynamic modeling of rivastigmine, a cholinesterase inhibitor, in patients with Alzheimer's disease. J Clin Pharmacol. 2001 Oct; 41(10):1082-90. Gobburu JV, Tammara V, Lesko L, Jhee SS, Sramek JJ, Cutler NR, Yuan R. PMID: 11583476.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCTClinical Trials
    29. Beta-amyloid therapies in Alzheimer's disease. Expert Opin Investig Drugs. 2001 Apr; 10(4):593-605. Jhee S, Shiovitz T, Crawford AW, Cutler NR. PMID: 11281811.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    30. Pharmacokinetics and pharmacodynamics of the triptan antimigraine agents: a comparative review. Clin Pharmacokinet. 2001; 40(3):189-205. Jhee SS, Shiovitz T, Crawford AW, Cutler NR. PMID: 11327198.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimals
    31. Pharmacokinetics of rizatriptan tablets during and between migraine attacks. Headache. 1999 Apr; 39(4):264-9. Cutler NR, Jhee SS, Majumdar AK, McLaughlin D, Brucker MJ, Carides AD, Kramer MS, Matzura-Wolfe D, Reines SA, Goldberg MR. PMID: 15613223.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    32. A double-blind, randomized, crossover assessment of blood pressure following administration of avitriptan, sumatriptan, or placebo to patients with mild to moderate hypertension. Cephalalgia. 1999 Mar; 19(2):95-9. Jhee SS, Salazar DE, Ford NF, Fulmor IE, Sramek JJ, Cutler NR. PMID: 10214534.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    33. NXX-066 in patients with Alzheimer's disease: a bridging study. Life Sci. 1999; 64(14):1215-21. Sramek JJ, Hourani J, Jhee SS, Cutler NR. PMID: 10210264.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    34. Pharmacokinetics and pharmacodynamics of avitriptan in patients with migraine after oral dosing. Headache. 1998 Jun; 38(6):446-52. Cutler NR, Salazar DE, Jhee SS, Fulmor IE, Ford N, Smith RA, Sramek JJ. PMID: 9664749.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    35. Dose-dependent CSF acetylcholinesterase inhibition by SDZ ENA 713 in Alzheimer's disease. Acta Neurol Scand. 1998 Apr; 97(4):244-50. Cutler NR, Polinsky RJ, Sramek JJ, Enz A, Jhee SS, Mancione L, Hourani J, Zolnouni P. PMID: 9576639.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCTClinical Trials
    36. A bridging study of LU 25-109 in patients with probable Alzheimer's disease. Life Sci. 1998; 62(3):195-202. Sramek JJ, Forrest M, Mengel H, Jhee SS, Hourani J, Cutler NR. PMID: 9488097.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    37. Initial safety, tolerability pharmacodynamics, and pharmacokinetics of CI-1007 in patients with schizophrenia. Psychopharmacol Bull. 1998; 34(1):93-9. Sramek JJ, Eldon MA, Posvar E, Feng MR, Jhee SS, Hourani J, Sedman AJ, Cutler NR. PMID: 9564205.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    38. A bridging study of fananserin in schizophrenic patients. Psychopharmacol Bull. 1998; 34(4):811-8. Sramek JJ, Kirkesseli S, Paccaly-Moulin A, Davidson J, Jhee SS, Hourani J, Sémiond D, Cutler NR. PMID: 10513457.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    39. Safety and tolerability of metrifonate in patients with Alzheimer's disease: results of a maximum tolerated dose study. Life Sci. 1998; 62(16):1433-41. Cutler NR, Jhee SS, Cyrus P, Bieber F, TanPiengco P, Sramek JJ, Gulanski B. PMID: 9585171.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    40. Monitoring of acute migraine attacks: placebo response and safety data. Headache. 1998 Jan; 38(1):35-8. Jhee SS, Salazar DE, Ford NF, Fulmor IE, Sramek JJ, Cutler NR. PMID: 9505001.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    41. Two rapid-dose titrations of sertindole in patients with schizophrenia. J Clin Psychopharmacol. 1997 Oct; 17(5):419-22. Sramek JJ, Mack RJ, Awni W, Hourani J, Jhee SS, Barto S, Cutler NR. PMID: 9315993.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    42. Penetration of trovafloxacin into cerebrospinal fluid in humans following intravenous infusion of alatrofloxacin. Antimicrob Agents Chemother. 1997 Jun; 41(6):1298-300. Cutler NR, Vincent J, Jhee SS, Teng R, Wardle T, Lucas G, Dogolo LC, Sramek JJ. PMID: 9174187; PMCID: PMC163903.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    43. Establishing the maximum tolerated dose of lesopitron in patients with generalized anxiety disorder: a bridging study. J Clin Psychopharmacol. 1996 Dec; 16(6):454-8. Sramek JJ, Fresquet A, Marion-Landais G, Hourani J, Jhee SS, Martinez L, Jensen CM, Bolles K, Carrington AT, Cutler NR. PMID: 8959472.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    44. Evaluation of cycloserine in the treatment of Alzheimer's disease. J Geriatr Psychiatry Neurol. 1995 Oct; 8(4):226-30. Fakouhi TD, Jhee SS, Sramek JJ, Benes C, Schwartz P, Hantsburger G, Herting R, Swabb EA, Cutler NR. PMID: 8561836.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCTClinical Trials
    45. Piperacillin-tazobactam pharmacokinetics in patients with intraabdominal infections. Pharmacotherapy. 1995 Jul-Aug; 15(4):472-8. Jhee SS, Kern JW, Burm JP, Yellin AE, Gill MA. PMID: 7479200.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    46. Placebo-controlled evaluation of three doses of a controlled-onset, extended-release formulation of verapamil in the treatment of stable angina pectoris. Am J Cardiol. 1995 Jun 01; 75(16):1102-6. Cutler NR, Anders RJ, Jhee SS, Sramek JJ, Awan NA, Bultas J, Lahiri A, Woroszylska M. PMID: 7762493.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    47. Pharmacoeconomics of piperacillin/tazobactam and imipenem/cilastatin in the treatment of patients with intra-abdominal infections. Clin Ther. 1995 Jan-Feb; 17(1):126-35. Jhee SS, Gill MA, Yellin AE, Berne TV, Heseltine PN, Appleman MD. PMID: 7758055.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCTClinical Trials
    48. Orthostasis in Alzheimer disease: a retrospective analysis. Alzheimer Dis Assoc Disord. 1995; 9(4):243-6. Jhee SS, Sramek JJ, Wardle TS, Cutler NR. PMID: 8749615.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    49. Stability of paclitaxel and fluconazole during simulated Y-site administration. Am J Hosp Pharm. 1994 Nov 01; 51(21):2704-6. Burm JP, Choi JS, Jhee SS, Chin A, Ulrich RW, Gill MA. PMID: 7856586.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    50. Stability of piperacillin sodium-tazobactam sodium and ranitidine hydrochloride in 0.9% sodium chloride injection during simulated Y-site administration. Am J Hosp Pharm. 1994 Sep 15; 51(18):2273-6. Choi JS, Burm JP, Jhee SS, Chin A, Ulrich RW, Gill MA. PMID: 7801988.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    51. Comparison of aminoglycoside pharmacokinetics in Asian, Hispanic, and Caucasian patients by using population pharmacokinetic methods. Antimicrob Agents Chemother. 1994 Sep; 38(9):2073-7. Jhee SS, Burm JP, Gill MA. PMID: 7811021; PMCID: PMC284686.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    52. Stability of paclitaxel with ondansetron hydrochloride or ranitidine hydrochloride during simulated Y-site administration. Am J Hosp Pharm. 1994 May 01; 51(9):1201-4. Burm JP, Jhee SS, Chin A, Moon YS, Jeong E, Nii L, Fox JL, Gill MA. PMID: 7913797.
      View in: PubMed   Mentions:    Fields:    
    53. Stability of ranitidine hydrochloride with ondansetron hydrochloride or fluconazole during simulated Y-site administration. Am J Hosp Pharm. 1994 Feb 01; 51(3):391-4. Pompilio FM, Fox JL, Inagaki K, Burm JP, Jhee S, Gill MA. PMID: 8160697.
      View in: PubMed   Mentions: 1     Fields:    
    54. Stability of ondansetron hydrochloride stored in a disposable, elastomeric infusion device at 4 degrees C. Am J Hosp Pharm. 1993 Sep; 50(9):1918-20. Jhee SS, Jeong EW, Chin A, Inagaki K, Fox JL, Gill MA. PMID: 8135242.
      View in: PubMed   Mentions:    Fields:    Translation:PHPublic Health