Sanjeet Patel

Photo of Sanjeet Patel
Title(s)Assistant Professor of Clinical Surgery
SchoolKeck School of Medicine of Usc
Address1520 San Pablo St.
Health Sciences Campus
Los Angeles CA 90033
ORCID ORCID Icon0000-0002-3303-4253 Additional info
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    Sanjeet G. Patel, MD, PhD, is an Assistant Professor of Clinical Surgery in the Division of Cardiothoracic Surgery at the Keck School of Medicine of USC and an attending cardiac surgeon at Keck Hospital of USC. His clinical practice covers adult cardiac surgery, with emphasis on mechanical circulatory support, heart transplantation, aortic and valve surgery, and hypertrophic obstructive cardiomyopathy, for which he serves as Surgical Director. He directs the Physician Scientist Training Program at the Keck School of Medicine. His research spans human pluripotent stem cell biology and cardiac cell therapy, machine learning for outcome prediction after cardiac surgery and mechanical circulatory support, and the genetic and metabolic mechanisms of atypical diabetes and aortopathy.

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    Collapse education and training
    Baylor College of Medicine, TexasMD06/2008Medicine
    UCLA, California06/2017General Surgery
    UCLA, California06/2014Molecular Biology
    USC, California06/2020Cardiothoracic Surgery
    Collapse awards and honors
    University of California, Los Angeles2017Wilma Miley Morton Award, Outstanding Research
    University of California, Los Angeles2017H & H Lee Travel Grant
    University of California, Los Angeles2014Dissertation of the Year, Molecular Biology Interdepartmental Program
    University of California, Los Angeles2011  - 2016Outstanding Student Teaching Award, General Surgery
    California Institute for Regenerative Medicine2011  - 2013CIRM Clinical Fellow Training Grant and competitive renewals

    Collapse Research 
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    USC Stimulating Access to Research in Residency (USC-StARR) Program
    NIH / National Heart, Lung, and Blood Institute 2R38HL155773Mar 1, 2024 - Jul 31, 2030
    Role: Principal Investigator (Multiple PI)
    Description: Multiple Principal Investigator with Fumito Ito. Competitive renewal awarded September 2025.
    Embryonic stem cell-derived extracellular vesicles for heart failure
    Children’s Hospital Los Angeles CHLA Core Pilot AwardJan 1, 2024 - Jun 30, 2024
    Role: Principal Investigator
    Description: Pilot award to test embryonic stem cell-derived extracellular vesicles as a cell-free therapy for heart failure.
    Health status outcomes after mitral valve surgery (CTSN CAROL ACT supplement)
    NIH / National Heart, Lung, and Blood Institute 3UM1HL117924-10S1Sep 1, 2023 - Feb 28, 2025
    Role: Co-Investigator
    Description: Led the patient-reported health status analysis for the Cardiothoracic Surgical Trials Network mitral valve cohort.
    Center for Identification and Study of Individuals with Atypical Diabetes Mellitus (RADIANT)
    NIH / National Institute of Diabetes and Digestive and Kidney Diseases U54DK118638Sep 1, 2018 - Jun 30, 2028
    Role: Site Principal Investigator (USC) and Co-Investigator
    Description: Leads the USC site of the RADIANT consortium; partner member of the metabolomics and genomics special interest group.
    USC-Saint Luke’s Mid America Heart Institute Cardiothoracic Surgical Trials Network Linked Clinical Research Center
    NIH / National Heart, Lung, and Blood Institute UM1HL117924Jul 15, 2013 - Feb 28, 2027
    Role: Co-Investigator
    Description: Surgical investigator for CTSN trials at Keck Medical Center of USC; no-cost extension through February 2027.
    Epigenetic instability of the X chromosome in human pluripotent stem cells
    California Institute for Regenerative Medicine TG2-01169Jul 1, 2010 - Jun 30, 2013
    Role: CIRM Clinical Fellow (predoctoral trainee)
    Description: CIRM Clinical Fellow training award held during doctoral research in the Plath laboratory at UCLA.
    Viral mechanisms of adipocyte dysfunction: role of Vpr
    NIH / National Institute of Diabetes and Digestive and Kidney Diseases R01DK081553May 1, 2009 - Mar 31, 2013
    Role: Collaborator
    Description: Stable isotope flux studies and analysis of adipose and hepatic dysfunction.
    Pathogenesis of ketosis-prone diabetes
    NIH / National Institute of Diabetes and Digestive and Kidney Diseases R21DK082827Apr 1, 2009 - Mar 31, 2011
    Role: Collaborator
    Description: Metabolic phenotyping and analysis of A-beta-positive ketosis-prone diabetes.

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    Collapse Bibliographic 
    Collapse publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Quality of life after mitral valve surgery: Results from the Cardiothoracic Surgical Trials Network. J Thorac Cardiovasc Surg. 2026 03; 171(3):615-622.e6. Patel SG, Spertus JA, Fu Z, Jones PG, Gelijns AC, Patel K, Raymond S, Ferket BS, Bagiella E, Smith PK, Acker MA, Starnes V, Arnold SV. PMID: 40885466; PMCID: PMC12552109.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    2. Comparison of waitlist and post-transplant outcomes in patients supported with total artificial heart versus continuous biventricular assist devices. Artif Organs. 2025 Feb; 49(2):281-291. Ferrall J, Vaidya AS, Kawaguchi ES, Patel SG, Lee RC, Lee ES, Wolfson AM. PMID: 39382237.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    3. An alternative technique in management of recipient left superior vena cava in orthotopic heart transplantation. JTCVS Tech. 2024 Dec; 28:109-111. Clothier JS, Harding A, Praeger J, Kobsa S, Patel S, Vaidya A, Dhillon A, Hackmann A, Baker C, Barr M, Starnes V, Lee R. PMID: 39669342; PMCID: PMC11632386.
      View in: PubMed   Mentions:
    4. The double barrel Impella exchange: A reliable method for uninterrupted mechanical circulatory support. J Heart Lung Transplant. 2024 Dec; 43(12):2031-2035. Clothier JS, Kobsa S, Praeger J, Bojko M, Barr M, Patel S, Dhillon A, Cash J, Lee R. PMID: 39029638.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Genetic architecture of heart mitochondrial proteome influencing cardiac hypertrophy. Elife. 2023 06 05; 12. Chella Krishnan K, El Hachem EJ, Keller MP, Patel SG, Carroll L, Vegas AD, Gerdes Gyuricza I, Light C, Cao Y, Pan C, Kaczor-Urbanowicz KE, Shravah V, Anum D, Pellegrini M, Lee CF, Seldin MM, Rosenthal NA, Churchill GA, Attie AD, Parker B, James DE, Lusis AJ. PMID: 37276142; PMCID: PMC10241513.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    6. Data Mining Framework for Discovering and Clustering Phenotypes of Atypical Diabetes. J Clin Endocrinol Metab. 2023 Mar 10; 108(4):834-846. Parikh HM, Remedios CL, Hampe CS, Balasubramanyam A, Fisher-Hoch SP, Choi YJ, Patel S, McCormick JB, Redondo MJ, Krischer JP. PMID: 36314086; PMCID: PMC10211492.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    7. Pancreatic Differentiation of Stem Cells Reveals Pathogenesis of a Syndrome of Ketosis-Prone Diabetes. Diabetes. 2021 Oct; 70(10):2419-2429. Yang D, Patel S, Szlachcic WJ, Chmielowiec J, Scaduto D, Putluri N, Sreekumar A, Suliburk J, Metzker M, Balasubramanyam A, Borowiak M. PMID: 34344789; PMCID: PMC8576504.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    8. Metabolomics Profiling of Patients With A-β+ Ketosis-Prone Diabetes During Diabetic Ketoacidosis. Diabetes. 2021 08; 70(8):1898-1909. Jahoor F, Hsu JW, Mehta PB, Keene KR, Gaba R, Mulukutla SN, Caducoy E, Peacock WF, Patel SG, Bennet R, Lernmark A, Balasubramanyam A. PMID: 34021044; PMCID: PMC8385613.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    9. Commentary: Standing on similar, but different, shoulders. J Thorac Cardiovasc Surg. 2020 08; 160(2):e81-e82. Patel S, Kim AW. PMID: 32037242.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Commentary: TiME may actually tell good from bad. J Thorac Cardiovasc Surg. 2020 04; 159(4):1613-1614. Patel S, Kim AW. PMID: 31982115.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    11. HIV-1 viral protein R (Vpr) induces fatty liver in mice via LXRa and PPARa dysregulation: implications for HIV-specific pathogenesis of NAFLD. Sci Rep. 2017 Oct 17; 7(1):13362. Agarwal N, Iyer D, Gabbi C, Saha P, Patel SG, Mo Q, Chang B, Goswami B, Schubert U, Kopp JB, Lewis DE, Balasubramanyam A. PMID: 29042644; PMCID: PMC5645472.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    12. Histone deacetylase inhibitors provoke a tumor supportive phenotype in pancreatic cancer associated fibroblasts. Oncotarget. 2017 Mar 21; 8(12):19074-19088. Nguyen AH, Elliott IA, Wu N, Matsumura C, Vogelauer M, Attar N, Dann A, Ghukasyan R, Toste PA, Patel SG, Williams JL, Li L, Dawson DW, Radu C, Kurdistani SK, Donahue TR. PMID: 27894105; PMCID: PMC5386671.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    13. Human Embryonic Stem Cells Do Not Change Their X Inactivation Status during Differentiation. Cell Rep. 2017 01 03; 18(1):54-67. Patel S, Bonora G, Sahakyan A, Kim R, Chronis C, Langerman J, Fitz-Gibbon S, Rubbi L, Skelton RJP, Ardehali R, Pellegrini M, Lowry WE, Clark AT, Plath K. PMID: 27989715; PMCID: PMC5214931.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansCells
    14. Chemotherapy-Induced Inflammatory Gene Signature and Protumorigenic Phenotype in Pancreatic CAFs via Stress-Associated MAPK. Mol Cancer Res. 2016 05; 14(5):437-47. Toste PA, Nguyen AH, Kadera BE, Duong M, Wu N, Gawlas I, Tran LM, Bikhchandani M, Li L, Patel SG, Dawson DW, Donahue TR. PMID: 26979711; PMCID: PMC4867256.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    15. p85α is a microRNA target and affects chemosensitivity in pancreatic cancer. J Surg Res. 2015 Jun 15; 196(2):285-293. Toste PA, Li L, Kadera BE, Nguyen AH, Tran LM, Wu N, Madnick DL, Patel SG, Dawson DW, Donahue TR. PMID: 25846727; PMCID: PMC4442711.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    16. X chromosome reactivation dynamics reveal stages of reprogramming to pluripotency. Cell. 2014 Dec 18; 159(7):1681-97. Pasque V, Tchieu J, Karnik R, Uyeda M, Sadhu Dimashkie A, Case D, Papp B, Bonora G, Patel S, Ho R, Schmidt R, McKee R, Sado T, Tada T, Meissner A, Plath K. PMID: 25525883; PMCID: PMC4282187.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    17. HIV-1 Vpr induces adipose dysfunction in vivo through reciprocal effects on PPAR/GR co-regulation. Sci Transl Med. 2013 Nov 27; 5(213):213ra164. Agarwal N, Iyer D, Patel SG, Sekhar RV, Phillips TM, Schubert U, Oplt T, Buras ED, Samson SL, Couturier J, Lewis DE, Rodriguez-Barradas MC, Jahoor F, Kino T, Kopp JB, Balasubramanyam A. PMID: 24285483; PMCID: PMC4009012.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    18. Proteomic and genomic approaches reveal critical functions of H3K9 methylation and heterochromatin protein-1γ in reprogramming to pluripotency. Nat Cell Biol. 2013 Jul; 15(7):872-82. Sridharan R, Gonzales-Cope M, Chronis C, Bonora G, McKee R, Huang C, Patel S, Lopez D, Mishra N, Pellegrini M, Carey M, Garcia BA, Plath K. PMID: 23748610; PMCID: PMC3733997.
      View in: PubMed   Mentions: 147     Fields:    Translation:AnimalsCells
    19. Pathogenesis of A?ß? ketosis-prone diabetes. Diabetes. 2013 Mar; 62(3):912-22. Patel SG, Hsu JW, Jahoor F, Coraza I, Bain JR, Stevens RD, Iyer D, Nalini R, Ozer K, Hampe CS, Newgard CB, Balasubramanyam A. PMID: 23160531; PMCID: PMC3581228.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    20. Integrative survival-based molecular profiling of human pancreatic cancer. Clin Cancer Res. 2012 Mar 01; 18(5):1352-63. Donahue TR, Tran LM, Hill R, Li Y, Kovochich A, Calvopina JH, Patel SG, Wu N, Hindoyan A, Farrell JJ, Li X, Dawson DW, Wu H. PMID: 22261810; PMCID: PMC3816537.
      View in: PubMed   Mentions: 129     Fields:    Translation:HumansCells
    21. Human monocytes accelerate proliferation and blunt differentiation of preadipocytes in association with suppression of C/EBPΑ mRNA. Obesity (Silver Spring). 2012 Feb; 20(2):253-62. Couturier J, Patel SG, Iyer D, Balasubramanyam A, Lewis DE. PMID: 21869759; PMCID: PMC4364279.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    22. Deficient synthesis of glutathione underlies oxidative stress in aging and can be corrected by dietary cysteine and glycine supplementation. Am J Clin Nutr. 2011 Sep; 94(3):847-53. Sekhar RV, Patel SG, Guthikonda AP, Reid M, Balasubramanyam A, Taffet GE, Jahoor F. PMID: 21795440; PMCID: PMC3155927.
      View in: PubMed   Mentions: 153     Fields:    Translation:HumansCellsCTClinical Trials
    23. Glutathione synthesis is diminished in patients with uncontrolled diabetes and restored by dietary supplementation with cysteine and glycine. Diabetes Care. 2011 Jan; 34(1):162-7. Sekhar RV, McKay SV, Patel SG, Guthikonda AP, Reddy VT, Balasubramanyam A, Jahoor F. PMID: 20929994; PMCID: PMC3005481.
      View in: PubMed   Mentions: 189     Fields:    Translation:Humans
    24. Effects of rosiglitazone on abnormal lipid kinetics in HIV-associated dyslipidemic lipodystrophy: a stable isotope study. Metabolism. 2011 Jun; 60(6):754-60. Sekhar RV, Patel SG, D'Amico S, Shi J, Balasubramanyam A, Rehman K, Jahoor F, Visnegarwala F. PMID: 20832829.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    25. Presence or absence of a known diabetic ketoacidosis precipitant defines distinct syndromes of "A-β+" ketosis-prone diabetes based on long-term β-cell function, human leukocyte antigen class II alleles, and sex predilection. Metabolism. 2010 Oct; 59(10):1448-55. Nalini R, Ozer K, Maldonado M, Patel SG, Hampe CS, Guthikonda A, Villanueva J, O'Brian Smith E, Gaur LK, Balasubramanyam A. PMID: 20170930; PMCID: PMC2888957.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    26. Microarray analysis of somatostatin receptor 5-regulated gene expression profiles in murine pancreas. World J Surg. 2009 Apr; 33(4):630-7. Patel SG, Zhou G, Liu SH, Li M, Jeong JW, DeMayo FJ, Gingras MC, Gibbs RA, Fisher WE, Brunicardi FC. PMID: 19137362.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
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