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Rong Lu, PhD

Photo of Rong Lu, PhD
Title(s)Professor of Stem Cell Biology & Regenerative Medicine, Biomedical Engineering and Gerontology
SchoolKeck School of Medicine of Usc
AddressBCC 306 1425 San Pablo Street
Health Sciences Campus
Los Angeles CA 90033
Phone+1 323 442 0169
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    Collapse Overview 

    Collapse Research 
    Collapse research activities and funding
    Investigating the heterogeneity and coordination of hematopoietic stem cells
    NIH R35HL150826Aug 1, 2020 - Jul 31, 2027
    Role: Principal Investigator
    Tracing the developmental origin of hematopoietic stem cell heterogeneity
    NIH R01HL138225Aug 28, 2017 - May 31, 2021
    Role: Principal Investigator
    Investigating the heterogeneous aging of individual hematopoietic stem cell clones
    NIH R01HL135292Aug 1, 2017 - Jul 31, 2022
    Role: Principal Investigator
    Lineage bias and clonal expansion of hematopoietic stem cell differentiation
    NIH R00HL113104Mar 10, 2014 - Feb 28, 2018
    Role: Principal Investigator
    Lineage bias and clonal expansion of hematopoietic stem cell differentiation
    NIH K99HL113104Jun 8, 2012 - Mar 31, 2014
    Role: Principal Investigator

    Collapse ORNG Applications 
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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Mitochondrial Protein Carboxyl-Terminal Alanine-Threonine Tailing Promotes Glioblastoma Tumor Growth by Regulating Mitochondrial Function. bioRxiv. 2025 Oct 22. Zhang B, Cai T, Reddy E, Wu Y, Mondal I, Tang Y, Gbufor AS, Wang J, Shen Y, Liu Q, Sun R, Ho WS, Lu RO, Wu Z. PMID: 38798583; PMCID: PMC11118334.
      View in: PubMed   Mentions:
    2. Advances in the understanding and therapeutic manipulation of cancer immune responsiveness: a Society for Immunotherapy of Cancer (SITC) review. J Immunother Cancer. 2025 Jan 16; 13(1). Cesano A, Augustin R, Barrea L, Bedognetti D, Bruno TC, Carturan A, Hammer C, Ho WS, Kather JN, Kirchhoff T, Lu RO, McQuade J, Najjar YG, Pietrobon V, Ruella M, Shen R, Soldati L, Spencer C, Betof Warner A, Warren S, Ziv E, Marincola FM. PMID: 39824527; PMCID: PMC11749597.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    3. Age-associated imbalance in immune cell regeneration varies across individuals and arises from a distinct subset of stem cells. Cell Mol Immunol. 2024 Dec; 21(12):1459-1473. Nogalska A, Eerdeng J, Akre S, Vergel-Rodriguez M, Lee Y, Bramlett C, Chowdhury AY, Wang B, Cess CG, Finley SD, Lu R. PMID: 39443746; PMCID: PMC11607082.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    4. A combination of protein phosphatase 2A inhibition and checkpoint immunotherapy: a perfect storm. Mol Oncol. 2024 Oct; 18(10):2333-2337. Clark MC, Lu RO, Ho WS, Dias MH, Bernards R, Forman SJ. PMID: 38932511; PMCID: PMC11459031.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    5. Interplay of RAP2 GTPase and the cytoskeleton in Hippo pathway regulation. J Biol Chem. 2024 05; 300(5):107257. Wu C, Cai X, Wang Y, Rodriguez CD, Zoaldi G, Herrmann L, Huang CY, Wang X, Sanghvi VR, Lu RO, Meng Z. PMID: 38574891; PMCID: PMC11067347.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    6. Interplay of RAP2 GTPase and the cytoskeleton in Hippo pathway regulation. bioRxiv. 2023 Oct 10. Wu C, Cai X, Wang Y, Rodriguez CD, Herrmann L, Zoaldi G, Huang CY, Wang X, Sanghvi VR, Lu RO, Meng Z. PMID: 37873252; PMCID: PMC10592777.
      View in: PubMed   Mentions:
    7. PP2Ac Deficiency Enhances Tumor Immunogenicity by Activating STING-Type I Interferon Signaling in Glioblastoma. Cancer Res. 2023 08 01; 83(15):2527-2542. Mondal I, Das O, Sun R, Gao J, Yu B, Diaz A, Behnan J, Dubey A, Meng Z, Eskandar E, Xu B, Lu RO, Ho WS. PMID: 37219874; PMCID: PMC10525036.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    8. PP2Ac/STRN4 negatively regulates STING-type I IFN signaling in tumor-associated macrophages. J Clin Invest. 2023 03 15; 133(6). Ho WS, Mondal I, Xu B, Das O, Sun R, Chiou P, Cai X, Tahmasebinia F, McFadden E, Wu CY, Wu Z, Matsui W, Lim M, Meng Z, Lu RO. PMID: 36757811; PMCID: PMC10014107.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    9. Acoustofluidic assembly of primary tumor-derived organotypic cell clusters for rapid evaluation of cancer immunotherapy. J Nanobiotechnology. 2023 Feb 04; 21(1):40. Wu Z, Ao Z, Cai H, Li X, Chen B, Tu H, Wang Y, Lu RO, Gu M, Cheng L, Lu X, Guo F. PMID: 36739414; PMCID: PMC9899402.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    10. Lineage tracking to reveal the fate of hematopoietic stem cells influenced by Flk2- multipotent progenitors after transplantation. Exp Mol Med. 2023 01; 55(1):205-214. Wang Z, Jiang D, Vergel-Rodriguez M, Nogalska A, Lu R. PMID: 36639717; PMCID: PMC9898540.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    11. Pantothenate kinase 2 interacts with PINK1 to regulate mitochondrial quality control via acetyl-CoA metabolism. Nat Commun. 2022 05 03; 13(1):2412. Huang Y, Wan Z, Tang Y, Xu J, Laboret B, Nallamothu S, Yang C, Liu B, Lu RO, Lu RO, Lu B, Feng J, Cao J, Hayflick S, Wu Z, Zhou B. PMID: 35504872; PMCID: PMC9065001.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    12. Deciphering intratumoral heterogeneity using integrated clonal tracking and single-cell transcriptome analyses. Nat Commun. 2021 11 11; 12(1):6522. Contreras-Trujillo H, Eerdeng J, Akre S, Jiang D, Contreras J, Gala B, Vergel-Rodriguez MC, Lee Y, Jorapur A, Andreasian A, Harton L, Bramlett CS, Nogalska A, Xiao G, Lee JW, Chan LN, Müschen M, Merchant AA, Lu R. PMID: 34764253; PMCID: PMC8586369.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    13. Inhibition of protein phosphatase-2A with LB-100 enhances antitumor immunity against glioblastoma. J Neurooncol. 2020 Jun; 148(2):231-244. Maggio D, Ho WS, Breese R, Walbridge S, Wang H, Cui J, Heiss JD, Gilbert MR, Kovach JS, Lu RO, Zhuang Z. PMID: 32342332; PMCID: PMC7467059.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    14. Clonal tracking using embedded viral barcoding and high-throughput sequencing. Nat Protoc. 2020 04; 15(4):1436-1458. Bramlett C, Jiang D, Nogalska A, Eerdeng J, Contreras J, Lu R. PMID: 32132718; PMCID: PMC7427513.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    15. Clonal-level lineage commitment pathways of hematopoietic stem cells in vivo. Proc Natl Acad Sci U S A. 2019 01 22; 116(4):1447-1456. Lu R, Czechowicz A, Seita J, Jiang D, Weissman IL. PMID: 30622181; PMCID: PMC6347684.
      View in: PubMed   Mentions: 55     Fields:    Translation:AnimalsCells
    16. Functional compensation between hematopoietic stem cell clones in vivo. EMBO Rep. 2018 08; 19(8). Nguyen L, Wang Z, Chowdhury AY, Chu E, Eerdeng J, Jiang D, Lu R. PMID: 29848511; PMCID: PMC6073208.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    17. Clonal reversal of ageing-associated stem cell lineage bias via a pluripotent intermediate. Nat Commun. 2017 02 22; 8:14533. Wahlestedt M, Erlandsson E, Kristiansen T, Lu R, Brakebusch C, Weissman IL, Yuan J, Martin-Gonzalez J, Bryder D. PMID: 28224997; PMCID: PMC5322498.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    18. Quantitative stability of hematopoietic stem and progenitor cell clonal output in rhesus macaques receiving transplants. Blood. 2017 03 16; 129(11):1448-1457. Koelle SJ, Espinoza DA, Wu C, Xu J, Lu R, Li B, Donahue RE, Dunbar CE. PMID: 28087539; PMCID: PMC5356453.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    19. Transplantation Dose Alters the Differentiation Program of Hematopoietic Stem Cells. Cell Rep. 2016 05 24; 15(8):1848-57. Brewer C, Chu E, Chin M, Lu R. PMID: 27184851; PMCID: PMC4880538.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    20. Sleeping beauty wakes up the clonal succession model for homeostatic hematopoiesis. Cell Stem Cell. 2014 Dec 04; 15(6):677-8. Lu R. PMID: 25479744.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    21. Clonal tracking of rhesus macaque hematopoiesis highlights a distinct lineage origin for natural killer cells. Cell Stem Cell. 2014 Apr 03; 14(4):486-499. Wu C, Li B, Lu R, Koelle SJ, Yang Y, Jares A, Krouse AE, Metzger M, Liang F, Loré K, Wu CO, Donahue RE, Chen ISY, Weissman I, Dunbar CE. PMID: 24702997; PMCID: PMC3979461.
      View in: PubMed   Mentions: 103     Fields:    Translation:HumansAnimalsCells
    22. Discriminating cellular heterogeneity using microwell-based RNA cytometry. Nat Commun. 2014 Mar 25; 5:3451. Dimov IK, Lu R, Lee EP, Seita J, Sahoo D, Park SM, Weissman IL, Lee LP. PMID: 24667995; PMCID: PMC4075946.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    23. Tracking single hematopoietic stem cells in vivo using high-throughput sequencing in conjunction with viral genetic barcoding. Nat Biotechnol. 2011 Oct 02; 29(10):928-33. Lu R, Neff NF, Quake SR, Weissman IL. PMID: 21964413; PMCID: PMC3196379.
      View in: PubMed   Mentions: 232     Fields:    Translation:AnimalsCells
    24. Systems-level dynamic analyses of fate change in murine embryonic stem cells. Nature. 2009 Nov 19; 462(7271):358-62. Lu R, Markowetz F, Unwin RD, Leek JT, Airoldi EM, MacArthur BD, Lachmann A, Rozov R, Ma'ayan A, Boyer LA, Troyanskaya OG, Whetton AD, Lemischka IR. PMID: 19924215; PMCID: PMC3199216.
      View in: PubMed   Mentions: 156     Fields:    Translation:AnimalsCells
    25. Automated microfluidic chromatin immunoprecipitation from 2,000 cells. Lab Chip. 2009 May 21; 9(10):1365-70. Wu AR, Hiatt JB, Lu R, Attema JL, Lobo NA, Weissman IL, Clarke MF, Quake SR. PMID: 19417902; PMCID: PMC4123551.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    26. A genomewide functional network for the laboratory mouse. PLoS Comput Biol. 2008 Sep 26; 4(9):e1000165. Guan Y, Myers CL, Lu R, Lemischka IR, Bult CJ, Troyanskaya OG. PMID: 18818725; PMCID: PMC2527685.
      View in: PubMed   Mentions: 71     Fields:    Translation:AnimalsCells
    27. Dissecting self-renewal in stem cells with RNA interference. Nature. 2006 Aug 03; 442(7102):533-8. Ivanova N, Dobrin R, Lu R, Kotenko I, Levorse J, DeCoste C, Schafer X, Lun Y, Lemischka IR. PMID: 16767105.
      View in: PubMed   Mentions: 476     Fields:    Translation:AnimalsCells
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    NIH Funding Acknowledgment: Important - All publications resulting from the utilization of SC CTSI resources are required to credit the SC CTSI grant by including the NIH funding acknowledgment and must comply with the NIH Public Access Policy.

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