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Clinico-Virological Outcomes and Mutational Profile of SARS-CoV-2 in Adults Treated with Ribavirin Aerosol for COVID-19 Pneumonia. Microorganisms. 2024 Jun 05; 12(6).
Morsica G, Messina E, Bagaglio S, Galli L, Lolatto R, Sampaolo M, Barakat M, Israel RJ, Castagna A, Clementi N. PMID: 38930529; PMCID: PMC11205916.
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Impact of Patient Subgroups on the Efficacy and Safety of Methylnaltrexone for Opioid-Induced Constipation in Patients with Advanced Illness. J Pain Res. 2023; 16:3529-3543.
Mehta N, Slatkin NE, Israel RJ, Stambler N, Shah ED. PMID: 37881233; PMCID: PMC10595216.
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PubMed Mentions:
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Methylnaltrexone Treatment for Opioid-Induced Constipation in Patients with and without Cancer: Effect of Initial Dose. J Pain Res. 2023; 16:2595-2607.
Chamberlain BH, Rhiner M, Slatkin NE, Stambler N, Israel RJ. PMID: 37533563; PMCID: PMC10391063.
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PubMed Mentions: Translation:
CTClinical Trials
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Reductions in All-Cause Mortality Associated with the Use of Methylnaltrexone for Opioid-Induced Bowel Disorders: A Pooled Analysis. Pain Med. 2023 Mar 01; 24(3):341-350.
Webster LR, Brenner D, Israel RJ, Stambler N, Slatkin NE. PMID: 36102822; PMCID: PMC9977130.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Subcutaneous Methylnaltrexone as Treatment for Opioid-Induced Constipation in Patients with Advanced Cancer and Noncancer Illnesses: A Post Hoc Analysis of Two Clinical Trials. J Pain Res. 2023; 16:395-406.
Shah ED, Chamberlain BH, Rhiner M, Slatkin NE, Stambler N, Israel RJ. PMID: 36798078; PMCID: PMC9926929.
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Cumulative Laxation Response with Methylnaltrexone: Implications for Hospitalized Patients with Advanced Illness and Opioid-Induced Constipation. Curr Ther Res Clin Exp. 2023; 98:100694.
Farchadi D, Slatkin NE, Stambler N, Israel RJ, Matus M. PMID: 36875317; PMCID: PMC9981808.
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A Randomized, Double-Blind, Parallel Design Thorough QT Study With a Nested Crossover to Compare the Cardiac Safety of Amiselimod With Placebo and Positive Control in Healthy Volunteers. Clin Pharmacol Drug Dev. 2023 03; 12(3):236-248.
Lee J, Lester R, O'Reilly T, Lowe ER, Slatkin NE, Franklin H, Israel RJ. PMID: 36708138.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Ribavirin aerosol in hospitalized adults with respiratory distress and COVID-19: An open-label trial. Clin Transl Sci. 2023 01; 16(1):165-174.
Poulakou G, Barakat M, Israel RJ, Bacci MR, Virazole Collaborator Group for COVID-19 Respiratory Distress. PMID: 36326174; PMCID: PMC9841304.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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A randomized, placebo-controlled study to evaluate safety and pharmacokinetics of inhaled ribavirin. Clin Transl Sci. 2022 09; 15(9):2159-2171.
Couroux P, Brkovic A, Vittitow JL, Israel RJ, Pamidi C, Patel J, Barakat M. PMID: 35677972; PMCID: PMC9468560.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Dosing of Rifaximin Soluble Solid Dispersion Tablets in Adults With Cirrhosis: 2 Randomized, Placebo-controlled Trials. Clin Gastroenterol Hepatol. 2023 03; 21(3):723-731.e9.
Bajaj JS, Hassanein TI, Pyrsopoulos NT, Sanyal AJ, Rahimi RS, Heimanson Z, Israel RJ, Rockey DC. PMID: 35750249.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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First-Dose Efficacy of Methylnaltrexone in Patients with Severe Medical Illness and Opioid-Induced Constipation: A Pooled Analysis. J Emerg Med. 2022 Feb; 62(2):231-239.
Peacock WF, Slatkin NE, Israel RJ, Stambler N. PMID: 34893381.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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P029 Pharmacokinetic/Pharmacodynamic Analysis of Amiselimod, a Selective Sphingosine 1-Phosphate Receptor Modulator, in Healthy Subjects: Results From a Phase 1 Study. Am J Gastroenterol. 2021 Dec 01; 116(Suppl 1):S7.
Lee J, Lester R, O'Reilly T, Lowe E, Slatkin N, Franklin H, Israel R. PMID: 37461948.
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PubMed Mentions:
1 Fields:
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Attrition of methylnaltrexone treatment-emergent adverse events in patients with chronic noncancer pain and opioid-induced constipation: a post hoc pooled analysis of two clinical trials. F1000Res. 2021; 10:891.
Mehta N, Slatkin NE, Israel RJ, Stambler N. PMID: 34631030; PMCID: PMC8485099.
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PubMed Mentions:
1 Fields:
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Subcutaneous Methylnaltrexone for Treatment of Opioid-Induced Constipation in Cancer versus Noncancer Patients: An Analysis of Efficacy and Safety Variables from Two Studies. J Pain Res. 2021; 14:2687-2697.
Chamberlain BH, Rhiner M, Slatkin NE, Stambler N, Israel RJ. PMID: 34512008; PMCID: PMC8420564.
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PubMed Mentions:
4
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Ribavirin Aerosol in the Treatment of SARS-CoV-2: A Case Series. Infect Dis Ther. 2021 Dec; 10(4):2791-2804.
Messina E, Danise A, Ferrari G, Andolina A, Chiurlo M, Razanakolona M, Barakat M, Israel RJ, Castagna A. PMID: 34302258; PMCID: PMC8302211.
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PubMed Mentions:
6
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The influence of brain metastases on the central nervous system effects of methylnaltrexone: a post hoc analysis of 3 randomized, double-blind studies. Support Care Cancer. 2021 Sep; 29(9):5209-5218.
Brenner DM, Slatkin NE, Stambler N, Israel RJ, Coluzzi PH. PMID: 33629189; PMCID: PMC8295095.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Malignancy Rates in Brodalumab Clinical Studies for Psoriasis. Am J Clin Dermatol. 2020 Jun; 21(3):421-430.
Gottlieb A, Lebwohl M, Liu C, Israel RJ, Jacobson A. PMID: 32207067; PMCID: PMC7275023.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Subcutaneous methylnaltrexone for opioid-induced constipation in advanced-illness patients with or without active cancer. Pain Manag. 2020 Mar; 10(2):73-84.
Chamberlain BH, Rhiner M, Slatkin NE, Stambler N, Israel RJ. PMID: 31951150.
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PubMed Mentions:
6 Fields:
Translation:
HumansCTClinical Trials
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Efficacy, Safety, and Patient-Reported Outcomes in Patients with Moderate-to-Severe Plaque Psoriasis Treated with Brodalumab for 5 Years in a Long-Term, Open-Label, Phase II Study. Am J Clin Dermatol. 2019 Dec; 20(6):863-871.
Lebwohl MG, Blauvelt A, Menter A, Papp KA, Guenthner S, Pillai R, Israel RJ, Jacobson A. PMID: 31493163; PMCID: PMC6872506.
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PubMed Mentions:
15 Fields:
Translation:
HumansCTClinical Trials
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Immunogenicity and skin clearance recapture in clinical studies of brodalumab. J Am Acad Dermatol. 2020 Feb; 82(2):344-351.
Bagel J, Lebwohl M, Israel RJ, Jacobson A. PMID: 31175910.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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Efficacy and safety of brodalumab in patients with psoriasis who had inadequate responses to ustekinumab: subgroup analysis of two randomized phase III trials. Br J Dermatol. 2019 02; 180(2):306-314.
Langley RG, Armstrong AW, Lebwohl MG, Blauvelt A, Hsu S, Tyring S, Rastogi S, Pillai R, Israel R. PMID: 30328108.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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Safety of oral methylnaltrexone for opioid-induced constipation in patients with chronic noncancer pain. J Pain Res. 2019; 12:139-150.
Rauck RL, Slatkin NE, Stambler N, Israel RJ. PMID: 30613162; PMCID: PMC6307492.
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PubMed Mentions:
3
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Oral methylnaltrexone is efficacious and well tolerated for the treatment of opioid-induced constipation in patients with chronic noncancer pain receiving concomitant methadone. J Pain Res. 2018; 11:2509-2516.
Webster LR, Israel RJ. PMID: 30425563; PMCID: PMC6205130.
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PubMed Mentions:
1
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Long-term safety results from a phase 3 open-label study of a fixed combination halobetasol propionate 0.01% and tazarotene 0.045% lotion in moderate-to-severe plaque psoriasis. J Am Acad Dermatol. 2019 Jan; 80(1):282-285.
Lebwohl MG, Sugarman JL, Gold LS, Pariser DM, Lin T, Pillai R, Martin G, Harris S, Israel R. PMID: 30227193.
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PubMed Mentions:
7 Fields:
Translation:
HumansCTClinical Trials
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Oral methylnaltrexone does not negatively impact analgesia in patients with opioid-induced constipation and chronic noncancer pain. J Pain Res. 2018; 11:1503-1510.
Webster LR, Israel RJ. PMID: 30147355; PMCID: PMC6095122.
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PubMed Mentions:
6
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Rifaximin is associated with modest, transient decreases in multiple taxa in the gut microbiota of patients with diarrhoea-predominant irritable bowel syndrome. Gut Microbes. 2019; 10(1):22-33.
Fodor AA, Pimentel M, Chey WD, Lembo A, Golden PL, Israel RJ, Carroll IM. PMID: 29708822; PMCID: PMC6363070.
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PubMed Mentions:
37 Fields:
Translation:
HumansCTClinical Trials
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Impact of previous biologic use on the efficacy and safety of brodalumab and ustekinumab in patients with moderate-to-severe plaque psoriasis: integrated analysis of the randomized controlled trials AMAGINE-2 and AMAGINE-3. Br J Dermatol. 2018 08; 179(2):320-328.
Papp KA, Gordon KB, Langley RG, Lebwohl MG, Gottlieb AB, Rastogi S, Pillai R, Israel RJ. PMID: 29488226.
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PubMed Mentions:
25 Fields:
Translation:
HumansCTClinical Trials
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Safety and efficacy of a fixed combination of halobetasol and tazarotene in the treatment of moderate-to-severe plaque psoriasis: Results of 2 phase 3 randomized controlled trials. J Am Acad Dermatol. 2018 Aug; 79(2):287-293.
Gold LS, Lebwohl MG, Sugarman JL, Pariser DM, Lin T, Martin G, Pillai R, Israel R, Ramakrishna T. PMID: 29614243.
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PubMed Mentions:
19 Fields:
Translation:
HumansCTClinical Trials
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Psychiatric adverse events during treatment with brodalumab: Analysis of psoriasis clinical trials. J Am Acad Dermatol. 2018 Jan; 78(1):81-89.e5.
Lebwohl MG, Papp KA, Marangell LB, Koo J, Blauvelt A, Gooderham M, Wu JJ, Rastogi S, Harris S, Pillai R, Israel RJ. PMID: 28985956.
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PubMed Mentions:
63 Fields:
Translation:
Humans
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Long-Term Safety and Efficacy of Subcutaneous Methylnaltrexone in Patients with Opioid-Induced Constipation and Chronic Noncancer Pain: A Phase 3, Open-Label Trial. Pain Med. 2017 Aug 01; 18(8):1496-1504.
Webster LR, Michna E, Khan A, Israel RJ, Harper JR. PMID: 28810695; PMCID: PMC5914419.
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PubMed Mentions:
12 Fields:
Translation:
HumansCTClinical Trials
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Rapid onset of action in patients with moderate-to-severe psoriasis treated with brodalumab: A pooled analysis of data from two phase 3 randomized clinical trials (AMAGINE-2 and AMAGINE-3). J Am Acad Dermatol. 2017 08; 77(2):372-374.
Blauvelt A, Papp KA, Lebwohl MG, Green LJ, Hsu S, Bhatt V, Rastogi S, Pillai R, Israel R. PMID: 28711089.
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PubMed Mentions:
25 Fields:
Translation:
Humans
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Randomized, Double-Blind Trial of Oral Methylnaltrexone for the Treatment of Opioid-Induced Constipation in Patients with Chronic Noncancer Pain. Pain Pract. 2017 07; 17(6):820-828.
Rauck R, Slatkin NE, Stambler N, Harper JR, Israel RJ. PMID: 27860208.
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PubMed Mentions:
29 Fields:
Translation:
HumansCTClinical Trials
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Antimicrobial Susceptibility of Staphylococcus Isolates from the Skin of Patients with Diarrhea-Predominant Irritable Bowel Syndrome Treated with Repeat Courses of Rifaximin. Antimicrob Agents Chemother. 2017 01; 61(1).
DuPont HL, Wolf RA, Israel RJ, Pimentel M. PMID: 27795384; PMCID: PMC5192100.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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An Open Letter to the Food and Drug Administration Regarding the Use of Morcellation Procedures in Women Having Surgery for Presumed Uterine Myomas. J Minim Invasive Gynecol. 2016 Mar-Apr; 23(3):303-8.
Parker W, Berek JS, Pritts E, Olive D, Kaunitz AM, Chalas E, Clarke-Pearson D, Goff B, Bristow R, Taylor HS, Farias-Eisner R, Fader AN, Maxwell GL, Goodwin SC, Love S, Gibbons WE, Foshag LJ, Leppert PC, Norsigian J, Nager CW, Johnson T, Guzick DS, As-Sanie S, Paulson RJ, Farquhar C, Bradley L, Scheib SA, Bilchik AJ, Rice LW, Dionne C, Jacoby A, Ascher-Walsh C, Kilpatrick SJ, Adamson GD, Siedhoff M, Israel R, Paraiso MF, Frumovitz MM, Lurain JR, Al-Hendy A, Benrubi GI, Raman SS, Kho RM, Anderson TL, Reynolds RK, DeLancey J. PMID: 26773577.
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PubMed Mentions:
3 Fields:
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Fixed-Dose Subcutaneous Methylnaltrexone in Patients with Advanced Illness and Opioid-Induced Constipation: Results of a Randomized, Placebo-Controlled Study and Open-Label Extension. J Palliat Med. 2015 Jul; 18(7):593-600.
Bull J, Wellman CV, Israel RJ, Barrett AC, Paterson C, Forbes WP. PMID: 25973526; PMCID: PMC4492709.
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PubMed Mentions:
29 Fields:
Translation:
Humans
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Characterization of abdominal pain during methylnaltrexone treatment of opioid-induced constipation in advanced illness: a post hoc analysis of two clinical trials. J Pain Symptom Manage. 2011 Nov; 42(5):754-60.
Slatkin NE, Lynn R, Su C, Wang W, Israel RJ. PMID: 22045373.
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PubMed Mentions:
14 Fields:
Translation:
Humans
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Methylnaltrexone for treatment of opioid-induced constipation in advanced illness patients. J Support Oncol. 2009 Jan-Feb; 7(1):39-46.
Slatkin N, Thomas J, Lipman AG, Wilson G, Boatwright ML, Wellman C, Zhukovsky DS, Stephenson R, Portenoy R, Stambler N, Israel R. PMID: 19278178.
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PubMed Mentions:
61 Fields:
Translation:
Humans
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Methylnaltrexone for opioid-induced constipation in advanced illness. N Engl J Med. 2008 May 29; 358(22):2332-43.
Thomas J, Karver S, Cooney GA, Chamberlain BH, Watt CK, Slatkin NE, Stambler N, Kremer AB, Israel RJ. PMID: 18509120.
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PubMed Mentions:
137 Fields:
Translation:
HumansCTClinical Trials
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Subcutaneous methylnaltrexone for the treatment of opioid-induced constipation in patients with advanced illness: a double-blind, randomized, parallel group, dose-ranging study. J Pain Symptom Manage. 2008 May; 35(5):458-68.
Portenoy RK, Thomas J, Moehl Boatwright ML, Tran D, Galasso FL, Stambler N, Von Gunten CF, Israel RJ. PMID: 18440447.
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PubMed Mentions:
41 Fields:
Translation:
Humans
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The relationship between physicians and industry: Faustian or symbiotic? Am J Obstet Gynecol. 2003 Jun; 188(6):1530-40.
Israel R. PMID: 12824990.
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Translation:
Humans
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Evaluation of a large cohort of men presenting for a screening semen analysis. Fertil Steril. 2000 Mar; 73(3):595-7.
Acacio BD, Gottfried T, Israel R, Sokol RZ. PMID: 10689019.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansCells