Parakrama Chandrasoma

Title(s)Retired Faculty
SchoolKeck School of Medicine of Usc
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    1. Intestinal Metaplasia of the "Cardia": Accurate Differentiation of Gastric or Esophageal Origin With an Expanded Biopsy Protocol. Am J Surg Pathol. 2021 07 01; 45(7):945-950. Yung E, Li X, Chandrasoma P. PMID: 33739789.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    2. Proposed approach to the challenging management of progressive gastroesophageal reflux disease. World J Gastrointest Endosc. 2018 Sep 16; 10(9):175-183. Labenz J, Chandrasoma PT, Knapp LJ, DeMeester TR. PMID: 30283600; PMCID: PMC6162253.
      View in: PubMed   Mentions: 3  
    3. How the pathologist can aid in the assessment of gastroesophageal reflux disease. Curr Opin Gastroenterol. 2018 07; 34(4):233-242. Chandrasoma P. PMID: 29708896.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    4. A Summary of the 2016 James W. Freston Conference of the American Gastroenterological Association: Intestinal Metaplasia in the Esophagus and Stomach: Origins, Differences, Similarities and Significance. Gastroenterology. 2017 Jul; 153(1):e6-e13. Spechler SJ, Merchant JL, Wang TC, Chandrasoma P, Fox JG, Genta RM, Goldenring JR, Hayakawa Y, Kuipers EJ, Lund PK, McKeon F, Mills JC, Odze RD, Peek RM, Pham T, Que J, Rustgi AK, Shaheen NJ, Shivdasani RA, Souza RF, Storz P, Todisco A, Wang DH, Wright NA. PMID: 28583825; PMCID: PMC5828164.
      View in: PubMed   Mentions: 13     Fields:    
    5. Intestinal Metaplasia is Present in Most if Not All Patients Who Have Undergone Endoscopic Mucosal Resection for Esophageal Adenocarcinoma. Am J Surg Pathol. 2016 Apr; 40(4):537-43. Smith J, Garcia A, Zhang R, DeMeester S, Vallone J, Chandrasoma P. PMID: 26813746.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    6. A New Pathologic Assessment of Gastroesophageal Reflux Disease: The Squamo-Oxyntic Gap. Adv Exp Med Biol. 2016; 908:41-78. Chandrasoma P, DeMeester T. PMID: 27573767.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    7. Emerging Concepts for the Endoscopic Management of Superficial Esophageal Adenocarcinoma. J Gastrointest Surg. 2016 Apr; 20(4):851-60. Greene CL, Worrell SG, Attwood SE, Chandrasoma P, Chang K, DeMeester TR, Lord RV, Montgomery E, Pech O, Vallone J, Vieth M, Wang KK, DeMeester SR. PMID: 26691147.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    8. Inter-Observer Variability in the Interpretation of Endoscopic Mucosal Resection Specimens of Esophageal Adenocarcinoma: Interpretation of ER specimens. J Gastrointest Surg. 2016 Jan; 20(1):140-4; discussion 144-5. Worrell SG, Boys JA, Chandrasoma P, Vallone JG, Dunst CM, Johnson CS, Lada MJ, Louie BE, Watson TJ, DeMeester SR. PMID: 26503261.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    9. Can the Risk of Lymph Node Metastases Be Gauged in Endoscopically Resected Submucosal Esophageal Adenocarcinomas? A Multi-Center Study. J Gastrointest Surg. 2016 Jan; 20(1):6-12; discussion 12. Boys JA, Worrell SG, Chandrasoma P, Vallone JG, Maru DM, Zhang L, Blackmon SH, Dickinson KJ, Dunst CM, Hofstetter WL, Lada MJ, Louie BE, Molena D, Watson TJ, DeMeester SR. PMID: 26408330.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    10. Inverted lymphoglandular polyp in descending colon. Case Rep Pathol. 2015; 2015:646270. Zhou S, Ma Y, Chandrasoma P. PMID: 25767731; PMCID: PMC4342070.
      View in: PubMed   Mentions: 3  
    11. Small bowel dissemination of coccidioidomycosis. Case Rep Pathol. 2015; 2015:403671. Zhou S, Ma Y, Chandrasoma P. PMID: 25685582; PMCID: PMC4313680.
      View in: PubMed   Mentions: 5  
    12. Strongyloidiasis hyperinfection in a patient with a history of systemic lupus erythematosus. Am J Trop Med Hyg. 2014 Oct; 91(4):806-9. Yung EE, Lee CM, Boys J, Grabo DJ, Buxbaum JL, Chandrasoma PT. PMID: 25092815; PMCID: PMC4183409.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    13. Histologic definition of gastro-esophageal reflux disease. Curr Opin Gastroenterol. 2013 Jul; 29(4):460-7. Chandrasoma PT. PMID: 23674188.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    14. Effect of Barrett's esophagus surveillance on esophageal preservation, tumor stage, and survival with esophageal adenocarcinoma. J Thorac Cardiovasc Surg. 2013 Jul; 146(1):31-7. Grant KS, DeMeester SR, Kreger V, Oh D, Hagen JA, Chandrasoma P, DeMeester TR. PMID: 23312980.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansPHPublic Health
    15. Columnar-lined esophagus without intestinal metaplasia has no proven risk of adenocarcinoma. Am J Surg Pathol. 2012 Jan; 36(1):1-7. Chandrasoma P, Wijetunge S, DeMeester S, Ma Y, Hagen J, Zamis L, DeMeester T. PMID: 21959311.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    16. The dilated distal esophagus: a new entity that is the pathologic basis of early gastroesophageal reflux disease. Am J Surg Pathol. 2011 Dec; 35(12):1873-81. Chandrasoma P, Wijetunge S, Ma Y, Demeester S, Hagen J, Demeester T. PMID: 21989338.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    17. Intraluminal pH and goblet cell density in Barrett's esophagus. J Gastrointest Surg. 2012 Mar; 16(3):469-74. Theodorou D, Ayazi S, DeMeester SR, Zehetner J, Peyre CG, Grant KS, Augustin F, Oh DS, Lipham JC, Chandrasoma PT, Hagen JA, DeMeester TR. PMID: 22095525.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    18. The histologic squamo-oxyntic gap: an accurate and reproducible diagnostic marker of gastroesophageal reflux disease. Am J Surg Pathol. 2010 Nov; 34(11):1574-81. Chandrasoma P, Wijetunge S, Demeester SR, Hagen J, Demeester TR. PMID: 20871393.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    19. Association of adenocarcinomas of the distal esophagus, "gastroesophageal junction," and "gastric cardia" with gastric pathology. Am J Surg Pathol. 2010 Oct; 34(10):1521-7. Wijetunge S, Ma Y, DeMeester S, Hagen J, DeMeester T, Chandrasoma P. PMID: 20871225.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    20. Prediction of patients with acute cholecystitis requiring emergent cholecystectomy: a simple score. Gastroenterol Res Pract. 2010; 2010:901739. Yacoub WN, Petrosyan M, Sehgal I, Ma Y, Chandrasoma P, Mason RJ. PMID: 20631896; PMCID: PMC2902011.
      View in: PubMed   Mentions: 22  
    21. Genetic variations in angiogenesis pathway genes predict tumor recurrence in localized adenocarcinoma of the esophagus. Ann Surg. 2010 May; 251(5):857-64. Lurje G, Leers JM, Pohl A, Oezcelik A, Zhang W, Ayazi S, Winder T, Ning Y, Yang D, Klipfel NE, Chandrasoma P, Hagen JA, DeMeester SR, DeMeester TR, Lenz HJ. PMID: 20101173.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    22. Progressive mucosal injury in patients with gastroesophageal reflux disease and increasing peripheral blood eosinophil counts. Arch Surg. 2010 Apr; 145(4):363-6. Banki F, Flanagan P, Zehetner J, Armstrong A, Hagen JA, Joshi A, Sinha R, Oh D, Oezcelik A, DeMeester SR, Abate E, Lipham JC, Chandrasoma P, Crookes PF, DeMeester TR. PMID: 20404287.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    23. Indications for routine pathologic examination of specimens removed during trauma operations. World J Surg. 2010 Apr; 34(4):733-7. Gertz R, Salim A, Teixeira P, Ley EJ, Inaba K, Chandrasoma P, Anderson D, Margulies DR. PMID: 20145929.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    24. Esophageal intraepithelial eosinophils in dysphagic patients with gastroesophageal reflux disease. Dig Dis Sci. 2010 Apr; 55(4):967-72. Ayazi S, Hagen JA, Chandrasoma P, Gholami P, Zehetner J, Oezcelik A, Lipham JC, Demeester SR, Demeester TR, Kline MM. PMID: 19960255.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    25. Phlegmonous gastritis in a patient with myeloid sarcoma: a case report. Appl Immunohistochem Mol Morphol. 2009 Oct; 17(5):458-62. Guo J, Young SK, Lorenzo CR, Lee CM, Kanel GC, Brynes RK, Chandrasoma P, Naritoku WY. PMID: 19644358.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    26. Esophageal pH exposure and epithelial cell differentiation. Dis Esophagus. 2009; 22(7):596-9. Chiu PW, Ayazi S, Hagen JA, Lipham JC, Zehetner J, Abate E, Oezcelik A, Hsieh CC, DeMeester SR, Banki F, Chandrasoma P, DeMeester TR. PMID: 19392851.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    27. Validation of a rodent model of Barrett's esophagus using quantitative gene expression profiling. Surg Endosc. 2009 Jun; 23(6):1346-52. Oh DS, DeMeester SR, Dunst CM, Mori R, Lehman BJ, Kuramochi H, Danenberg K, Danenberg P, Hagen JA, Chandrasoma P, DeMeester TR. PMID: 18813976.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    28. The price of doubt is esophageal adenocarcinoma. Ann Surg. 2008 Mar; 247(3):558-9; author reply 559-60. Chandrasoma P. PMID: 18376213.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    29. Carditis is esophageal and caused by GERD; it is not gastric. Am J Surg Pathol. 2008 Feb; 32(2):341-2; author reply 342. Chandrasoma P. PMID: 18223343.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    30. High intraepithelial eosinophil counts in esophageal squamous epithelium are not specific for eosinophilic esophagitis in adults. Am J Gastroenterol. 2008 Feb; 103(2):435-42. Rodrigo S, Abboud G, Oh D, DeMeester SR, Hagen J, Lipham J, DeMeester TR, Chandrasoma P. PMID: 18289205.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansCells
    31. What is adenocarcinoma of the esophagogastric junction? Am J Gastroenterol. 2008 Feb; 103(2):492-3. Chandrasoma P. PMID: 18289219.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    32. Lack of reversal of carditis by PPI therapy only means that acid in refluxate is not responsible for carditis. Dig Dis Sci. 2008 May; 53(5):1426-7. Chandrasoma PT. PMID: 18231853.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    33. Histopathology of the endoscopic esophagogastric junction in patients with gastroesophageal reflux disease. Wien Klin Wochenschr. 2008; 120(11-12):350-9. Ringhofer C, Lenglinger J, Izay B, Kolarik K, Zacherl J, Eisler M, Wrba F, Chandrasoma PT, Cosentini EP, Prager G, Riegler M. PMID: 18709523.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    34. Four directed biopsies are better than eight random biopsies to find intestinal metaplasia in columnar lined esophagus. Am J Gastroenterol. 2007 Oct; 102(10):2352-3; author reply 2353-4. Chandrasoma P. PMID: 17897347.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    35. Towards the molecular characterization of disease: comparison of molecular and histological analysis of esophageal epithelia. J Gastrointest Surg. 2007 Sep; 11(9):1095-104. Vallböhmer D, Marjoram P, Kuramochi H, Shimizu D, Jung H, DeMeester SR, Oh D, Chandrasoma PT, Danenberg KD, DeMeester TR, Danenberg PV, Peters JH. PMID: 17623264.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    36. Anti-reflux surgery is superior to medical management in patients with Barrett's esophagus with low-grade dysplasia. Am J Gastroenterol. 2007 Sep; 102(9):2111-2. Chandrasoma P. PMID: 17727447.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    37. Reduction of interleukin 8 gene expression in reflux esophagitis and Barrett's esophagus with antireflux surgery. Arch Surg. 2007 Jun; 142(6):554-9; discussion 559-60. Oh DS, DeMeester SR, Vallbohmer D, Mori R, Kuramochi H, Hagen JA, Lipham J, Danenberg KD, Danenberg PV, Chandrasoma P, DeMeester TR. PMID: 17576892.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    38. Adenocarcinomas of the distal esophagus and "gastric cardia" are predominantly esophageal carcinomas. Am J Surg Pathol. 2007 Apr; 31(4):569-75. Chandrasoma P, Wickramasinghe K, Ma Y, DeMeester T. PMID: 17414104.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    39. Is intestinal metaplasia a necessary precursor lesion for adenocarcinomas of the distal esophagus, gastroesophageal junction and gastric cardia? Dis Esophagus. 2007; 20(1):36-41. Chandrasoma P, Wickramasinghe K, Ma Y, DeMeester T. PMID: 17227308.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    40. Body mass index is associated with Barrett esophagus and cardiac mucosal metaplasia. Dig Dis Sci. 2006 Sep; 51(9):1589-94. Bu X, Ma Y, Der R, Demeester T, Bernstein L, Chandrasoma PT. PMID: 16927134.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    41. Increasing cyclooxygenase-2 (cox-2) gene expression in the progression of Barrett's esophagus to adenocarcinoma correlates with that of Bcl-2. Int J Cancer. 2006 Aug 15; 119(4):765-70. Shimizu D, Vallböhmer D, Kuramochi H, Uchida K, Schneider S, Chandrasoma PT, Shimada H, DeMeester TR, Danenberg KD, Peters JH, DeMeester SR, Danenberg PV. PMID: 16550596.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    42. Antireflux surgery normalizes cyclooxygenase-2 expression in squamous epithelium of the distal esophagus. Am J Gastroenterol. 2006 Jul; 101(7):1458-66. Vallböhmer D, DeMeester SR, Oh DS, Banki F, Kuramochi H, Shimizu D, Hagen JA, Danenberg KD, Danenberg PV, Chandrasoma PT, Peters JH, DeMeester TR. PMID: 16863546.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    43. Clinical biology and surgical therapy of intramucosal adenocarcinoma of the esophagus. J Am Coll Surg. 2006 Aug; 203(2):152-61. Oh DS, Hagen JA, Chandrasoma PT, Dunst CM, Demeester SR, Alavi M, Bremner CG, Lipham J, Rizzetto C, Cote R, Demeester TR. PMID: 16864027.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    44. Molecular determinants in targeted therapy for esophageal adenocarcinoma. Arch Surg. 2006 May; 141(5):476-81; discussion 481-2. Vallböhmer D, Peters JH, Kuramochi H, Oh D, Yang D, Shimizu D, DeMeester SR, Hagen JA, Chandrasoma PT, Danenberg KD, Danenberg PV, DeMeester TR. PMID: 16702519.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    45. RE: Odze RD. unraveling the mystery of the gastroesophageal junction: a pathologist's perspective. Am J Gastroenterol. 2006 Jan; 101(1):199; author reply 199-200. Chandrasoma P. PMID: 16405557.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    46. A proposal for a new validated histological definition of the gastroesophageal junction. Hum Pathol. 2006 Jan; 37(1):40-7. Chandrasoma P, Makarewicz K, Wickramasinghe K, Ma Y, Demeester T. PMID: 16360414.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    47. Survivin, a potential biomarker in the development of Barrett's adenocarcinoma. Surgery. 2005 Oct; 138(4):701-6; discussion 706-7. Vallböhmer D, Peters JH, Oh D, Kuramochi H, Shimizu D, Demeester SR, Hagen JA, Chandrasoma PT, Danenberg KD, DeMeester TR, Danenberg P. PMID: 16269299.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    48. Controversies of the cardiac mucosa and Barrett's oesophagus. Histopathology. 2005 Apr; 46(4):361-73. Chandrasoma P. PMID: 15810947.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    49. Quantitative, tissue-specific analysis of cyclooxygenase gene expression in the pathogenesis of Barrett's adenocarcinoma. J Gastrointest Surg. 2004 Dec; 8(8):1007-16; discussion 1016-7. Kuramochi H, Vallböhmer D, Uchida K, Schneider S, Hamoui N, Shimizu D, Chandrasoma PT, DeMeester TR, Danenberg KD, Danenberg PV, Peters JH. PMID: 15585388.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    50. Identification of hibernating myocardium by acoustic microscopy. Ultrasound Med Biol. 2004 May; 30(5):693-6. Ng DW, Sathish S, Khan A, Chandrasoma P, Wijns W, Chandraratna PA. PMID: 15183236.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    51. Pathological basis of gastroesophageal reflux disease. World J Surg. 2003 Sep; 27(9):986-93. Chandrasoma P. PMID: 14560363.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    52. Histologic classification of patients based on mapping biopsies of the gastroesophageal junction. Am J Surg Pathol. 2003 Jul; 27(7):929-36. Chandrasoma PT, Der R, Ma Y, Peters J, Demeester T. PMID: 12826885.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    53. Barrett's esophagus can and does regress after antireflux surgery: a study of prevalence and predictive features. J Am Coll Surg. 2003 May; 196(5):706-12; discussion 712-3. Gurski RR, Peters JH, Hagen JA, DeMeester SR, Bremner CG, Chandrasoma PT, DeMeester TR. PMID: 12742201.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    54. Cardiac mucosal changes in a pediatric population. Am J Surg Pathol. 2003 Feb; 27(2):274-5; author reply 276-7. Chandrasoma P. PMID: 12548179.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    55. Histopathology of the gastroesophageal junction: a study on 36 operation specimens. Am J Surg Pathol. 2003 Feb; 27(2):277-8. Chandrasoma P. PMID: 12548180.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    56. Cytokeratin and DAS-1 immunostaining reveal similarities among cardiac mucosa, CIM, and Barrett's esophagus. Am J Gastroenterol. 2002 Oct; 97(10):2514-23. DeMeester SR, Wickramasinghe KS, Lord RV, Friedman A, Balaji NS, Chandrasoma PT, Hagen JA, Peters JH, DeMeester TR. PMID: 12385432.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    57. Fasciola hepatica and parasitic eosinophilic granuloma of the Liver. Am J Surg Pathol. 2002 Sep; 26(9):1238. Vercelli-Retta J, Lagios MD, Chandrasoma P. PMID: 12218584.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    58. Detection of Barrett's epithelium by acoustic microscopy. Ultrasound Med Biol. 2002 Feb; 28(2):203-7. Wickramasinghe KS, Chandrasoma PT, Chandraratna PA. PMID: 11937283.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    59. Microcalcification in the breast and the pathologist. Am J Surg Pathol. 2002 Jan; 26(1):135-6. Chandrasoma PT. PMID: 11756783.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
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